the role of adrenergic beta receptors for skin pigmentation
the role of adrenergic beta receptors for skin pigmentation
the role of adrenergic beta receptors for skin pigmentation
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Investigating <strong>the</strong> function <strong>of</strong> Adrenergic Receptor (ADR)<br />
– applying siRNA technique to B16 melanoma cells<br />
• Knocked down 9 ADR genes with siRNA and measure melanin syn<strong>the</strong>sis<br />
in B16 melanoma cell<br />
Melanocyte<br />
melanosome<br />
Ø<br />
Melanin Production<br />
Genome<br />
Nucleus<br />
ADR<br />
mRNA<br />
Small interfering (si) RNA<br />
<strong>for</strong> <strong>adrenergic</strong> receptor<br />
genes interfere ADR gene<br />
expression
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