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the role of adrenergic beta receptors for skin pigmentation

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Screening <strong>of</strong> ADRB Antagonist<br />

Undecylenoyl Phenylalanine works as an antagonist <strong>of</strong> ADRB1 & 2<br />

N-undecyl-10-L-phenylalanine<br />

Effect <strong>of</strong> Undecylenoyl Phenylalanine<br />

on Adrenergic Receptor B1<br />

Effect <strong>of</strong> Undecylenoyl Phenylalanine<br />

on Adrenergic Receptor B2<br />

100<br />

90<br />

120<br />

% Inhibition vs. control<br />

80<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

1.44E-05 0.00036 0.009 0.045<br />

Undecylenoyl Phenylalanine concentration [%]<br />

% inhibition vs. control<br />

100<br />

80<br />

60<br />

40<br />

20<br />

0<br />

0.0003 0.0009 0.0028 0.0084<br />

Undecylenoyl Phenylalanine concentration [%]

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