the role of adrenergic beta receptors for skin pigmentation
the role of adrenergic beta receptors for skin pigmentation
the role of adrenergic beta receptors for skin pigmentation
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Adrenergic Receptors<br />
Up-regulated Genes in Solar Lentigo Skin<br />
Acr Title Fold change spot vs. normal P-value<br />
ADRB1 Adrenergic Receptor <strong>beta</strong>-1 14.5 0.044<br />
• Adrenaline – related to stress deeply, a<br />
hormone, increases heart rate, contracts<br />
blood vessels, etc.<br />
• Adrenergic receptor - 2 main groups, α<br />
and β, with several subtypes<br />
• Adrenergic Receptor <strong>beta</strong>-2 antagonist<br />
accelerates <strong>skin</strong> barrier recovery and<br />
reduces epidermal hyperplasia induced<br />
by barrier disruption (JID 2003)<br />
• Adrenergic Receptor <strong>beta</strong>-2 UVB<br />
irradiation increases adrenaline release<br />
by keratinocytes, which can streng<strong>the</strong>n<br />
melanin syn<strong>the</strong>sis (JID 2008)<br />
Reference; wikipedia
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