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the role of adrenergic beta receptors for skin pigmentation

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Topical application <strong>of</strong> 1% Undecylenoyl Phenylalanine<br />

containing moisturizer reduced melanin amount in<br />

ex vivo human tissue model<br />

1% Undecylenoyl Phenylalanine-containing Moisturizer<br />

Reduces Melanin Amount in Human Skin Explant Model<br />

Melanin amount measured by image analysis <strong>of</strong><br />

stained cross-sectional images (day 6)<br />

800<br />

700<br />

600<br />

500<br />

400<br />

300<br />

200<br />

100<br />

0<br />

1% UP in Vehicle Vehicle moisturizer<br />

• Tissue from abdominal, Skin type III, Tissue was cultured with treatment <strong>for</strong> 6 days, N=6 samples <strong>for</strong> each

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