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The Frontal lobes - Mahidol University

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19/07/54<br />

Language Impairment<br />

Broca's area resides in the left frontal<br />

lobe and lesion of this area produces a<br />

well‐known impairment of language<br />

referred to as Broca's aphasia.<br />

Patients with dorsolateral frontal lobe<br />

lesions may also have additional<br />

language impairment that is distinct<br />

from Broca's aphasia.<br />

Language Impairment<br />

<strong>The</strong> first of these is a general reduction of<br />

language production although language<br />

utterances that are produced are fluent<br />

and maintain correct syntax.<br />

Patients with frontal lobe lesions have<br />

difficulty initiating speech and<br />

maintaining a complex, spontaneous<br />

conversation.<br />

Language Impairment<br />

This is referred to as a deficit in<br />

"verbal fluency", although language<br />

productions are actually fluent.<br />

Language Impairment<br />

Patients with frontal lesions in secondary<br />

motor control areas may also display<br />

mutism.<br />

In particular, lesions of the cingulum often<br />

result in essential mutism.<br />

Here, the patient comprehends language but<br />

cannot produce any vocalizations, including<br />

language.<br />

Language Impairment<br />

This is viewed as a deficit of the basic<br />

motor control of the oral apparatus to<br />

the point where there is no initiation of<br />

activity.<br />

<strong>The</strong> patient is often indifferent to<br />

communication in general and does<br />

not show the frustration characteristic<br />

of Broca's aphasia.<br />

Language Impairment<br />

A pure agraphia is also associated with<br />

lesions of supplemental motor areas of the<br />

left dorsolateral frontal lobe (Exner's<br />

area).<br />

Exner's area (Broadman area #46<br />

46) is above<br />

Broca's area (Broadman area #44,45) and<br />

anterior to the primary motor control area.<br />

In this disorder, the patient is not aphasic<br />

but has difficulty writing and reading.<br />

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