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Combinatorial Chemistry and Drug Discovery Lab Jasmine ... - haspi

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Three Major Classes of<br />

Antibacterial Agents<br />

Controlling the growth of microorganims usually<br />

involves the use of physical or chemical agents which<br />

either kill or prevent the growth of microorganisms.<br />

1) Bactericidal – agents that kill bacteria are called cidal<br />

agents; also referred to as bactericides.<br />

2) Bacteriostatic – agents which inhibit the growth of cells<br />

(without killing them) are referred to as static agents.<br />

3) Bacteriolytic – agents that have the ability to lyse or<br />

break apart, dissolve, <strong>and</strong> destroy bacteria by the use of an<br />

enzyme or other agent.<br />

Bacteria have the ability to develop resistance following<br />

repeated or subclinical (insufficient) doses, so more<br />

advanced antibiotics <strong>and</strong> synthetic antimicrobials are<br />

continually required to overcome them.

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