Combinatorial Chemistry and Drug Discovery Lab Jasmine ... - haspi

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Antibacterial Sites of Action
Concept Review • Analyze the graph by describing the phase of growth being represented by lines A thru E: LAG, LOG, STATIONARY, or DEATH. • If the graph shown is the result of antibiotic resistance testing, what is the effect of the antibiotics on the growth of the bacteria at A thru E: NORMAL, BACTERIOSTATIC, RESISTANT or BACTERICIDAL?
Page 1 and 2: Combinatorial Chemistry and Drug Di
Page 3 and 4: Overview • In this lab students w
Page 5 and 6: National Science Education Standard
Page 7 and 8: Chemicals CHEMICAL VENDOR CATALOG #
Page 9 and 10: Presenter Notes Preparing Overnight
Page 11 and 12: Presenter Notes Spectrophotometer 1
Page 13 and 14: Instructor Notes If mixtures are no
Page 15 and 16: Tips for handling E.coli: Lab Safet
Page 17 and 18: During the EXPONENTIAL or LOG PHASE
Page 19 and 20: Ouchterlony Test •A double diffus
Page 21 and 22: Label transfer pipettes 1. Label 6
Page 23 and 24: Label Petri dishes M1 M2 M4 M5 A#B1
Page 25 and 26: Prepare mixtures (libraries) 1. Mak
Page 27 and 28: Incubate at 37ºC or store at room
Page 29 and 30: Chemical Structures of Synthesized
Page 31 and 32: Data Analysis - + = no inhibition o
Page 33 and 34: Extension: Kirby-Bauer Test Determi
Page 35 and 36: Extension: Zone Size Interpretive C
Page 37 and 38: Results at Room Temperature
Page 39 and 40: Combinatorial Chemistry and Drug Di
Page 41 and 42: Three Major Classes of Antibacteria
Page 46: Great Job Jasmine Erfe!

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