Metabolic and Biochemical Alterations in Alzheimer Disease: Facts ...
Metabolic and Biochemical Alterations in Alzheimer Disease: Facts ...
Metabolic and Biochemical Alterations in Alzheimer Disease: Facts ...
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<strong>Metabolic</strong> <strong>and</strong> <strong>Biochemical</strong> <strong>Alterations</strong><br />
<strong>in</strong> <strong>Alzheimer</strong> <strong>Disease</strong>: <strong>Facts</strong> <strong>and</strong> Fictions<br />
Prof. Mark A. Smith<br />
In situ oxidation of 3,3’ diam<strong>in</strong>obenzid<strong>in</strong>e<br />
(chelation)<br />
<strong>Alzheimer</strong> disease 10mM DFX 10mM DTPA<br />
Proc Natl Acad Sci U S A., 94, 9866-8 (1997)<br />
34<br />
Iron histochemistry<br />
AD<br />
Ctl<br />
DFX<br />
Proc Natl Acad Sci U S A., 94, 9866-8 (1997)<br />
DFX/Fe<br />
35<br />
Redox active metals are also <strong>in</strong> cytoplasm<br />
36<br />
The screen versions of these slides have full details of copyright <strong>and</strong> acknowledgements<br />
12
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