Role of glycated LDL in diabetic atherosclerosis

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? What about other LDL Modification
Naturally occurring atherogenic modifications of lipoproteins include oxidation, glycation & glycoxidation glycoxidation Modified LDL is considered to be a risk factor for the development and progression of atherosclerosis. glycated LDL is present in the circulation at much higher concentration than oxidized LDL, even in non-diabetic people & can stimulate foam cell formation. Witztum JL, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. J Clin Invest 1991; 88:1785–1792.& Tanaka, Akira Atherosclerosis, Volume 52 Springer Protocols – Jan 1, 2001
Page 1 and 2: Prof. Sanaa Gazareen, MD Head of Di
Page 3 and 4: Pathogenic mechanisms involved in t
Page 5 and 6: IN DM: LDLc Routine LAB. Measuremen
Page 7 and 8: The primary atherogenic lipoprotein
Page 9: LDL Oxidation • Although LDL oxid
Page 13 and 14: Small dense-LDL is the most glycate
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Page 17: Factors Influencing Plasma Level of
Page 20 and 21: “ Glycated LDL “Ultra-bad Chole
Page 22 and 23: • Prevention and treatment
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Page 27 and 28: Treatment of Diabetic Dyslipidemia
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Role of glycated LDL in diabetic atherosclerosis

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