Biennial Report 2011â2012

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Doctoral theses Name Title Supervisor 2011 R. Gerasimaitė A directed evolution design of target specificity and kinetic prof. S.Klimašauskas analysis of conformational transitions in the HhaI methyltransferas I. Kučinskaitė-Kodzė Production, characterization and application of new dr. A. Žvirblienė monoclonal antibodies against viral antigens M. Juozapaitis Synthesis of Paramyxoviridae nucleoproteins in yeast prof. K. Sasnauskas Saccharomyces Cerevisiae and their application in viral diagnostics. E. Mažeikė Generation of model anticancer vaccine based on dr. A. Gedvilaitė virus-like particles E. Čiplys Analysis of maturation of measles virus hemaglutinin in yeast dr. R. Slibinskas S.cerevisiae and P.Pastoris secretory pathway and humanization prof. K.Sasnauskas of Yeast cells 2012 Z. Liutkevičiūtė DNA cytosine methyltransferase-directed reactions involving prof. S.Klimašauskas non-cofactor-like compounds A. Šilanskas Restriction endonuclease-triplex forming oligonucleotide prof. dr. V. Šikšnys conjugates with controllable catalytic activity D. Golovenko Structural and functional studies of restriction endonucleases dr. S. Gražulis EcoRII, BfiI and Bse634I prof. dr. V. Šikšnys G. Gasiūnas Mechanism of DNA interference by Type II CRISPR/Cas systems prof. dr. V. Šikšnys 14
Rūta Gerasimaitė enjoys a traditional gift from her colleagues From left to right altogether Arūnas Šilanskas, Giedrius Gasiūnas, Zita Liutkevičiūtė and Dmitrij Golovenko who defended PhD theses at the Institute of Biotechnology in 2012 Just „released“ doctor Dmitrij Golovenko with scientific consultants Dr. S.Gražulis (on left) and Prof. Dr. V. Šikšnys Eglė Mažeikė at the 14th International Congress of Immunology in Kobe, August 2010 Indrė Kučinskaitė-Kodzė with the award of the Lithuanian Academy of Sciences for PhD theses in the field of biotechnology, 2012 March Evaldas Čiplys enjoys the moment after defending his PhD theses Vilnius University Institute of Biotechnology <strong>Biennial</strong> report for 2011–2012 15
Page 1 and 2: Vilnius University Institute of Bio
Page 3 and 4: Vilnius University Institute of Bio
Page 5 and 6: Director’s note The Biennial repo
Page 7 and 8: Crystallographers Dr. Giedrė Tamul
Page 9 and 10: Financing Sources 2012 3.7 MEuros L
Page 11 and 12: European Economic Area Title Head o
Page 13 and 14: Interspecific hybrids of orchard pl
Page 15: AGENCY FOR SCIENCE, INNOVATION AND
Page 19 and 20: References 1. Gražulis, S.; Chatei
Page 21 and 22: A B Prof. Irutė Meškienė, PhD, D
Page 23 and 24: Rasa Rakauskaitė, PhD Engineering
Page 25 and 26: At this point we try to compare elo
Page 27 and 28: Project Management To ensure succes
Page 29 and 30: Research overview Structure and mol
Page 31 and 32: does not increase Bse634I fidelity
Page 33 and 34: This establishes a molecular basis
Page 35 and 36: Publications 2011-2012 1. Sinkunas
Page 37 and 38: AdoMet-dependent methyltransferases
Page 39 and 40: Engineering the catalytic reaction
Page 41 and 42: Archaeal C/D box RNPs: syntheticall
Page 43 and 44: Selected Publications 2011-2012 Pat
Page 45 and 46: Human metapneumovirus Human metapne
Page 47 and 48: Figure 3. Electron micrograph of Cs
Page 49 and 50: PhD students Robertas Galinis and J
Page 51 and 52: Publications 2011-2012 1. Zielonka
Page 53 and 54: Generation of recombinant virus-lik
Page 55 and 56: protein contains a bHLH domain and
Page 57 and 58: Publications 2011-2012 1. Kucinskai
Page 59 and 60: The Department of Biothermodynamics
Page 61 and 62: Figure 2. Contributions from linked
Page 63 and 64: Thermodynamics of the Hydrophobic e
Page 65 and 66: Publications 2011-2012 1. Čapkausk
Page 67 and 68:
At present computational methods ar
Page 69 and 70:
tion of experts in the field. The o
Page 71 and 72:
Collaborative interactions Selected
Page 73 and 74:
Sector of Applied Biocatalysis was
Page 75 and 76:
Start-ups UAB Baltymas is a small L
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Biennial Report 2011â2012