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PASS Scripta Varia 21 - Pontifical Academy of Sciences

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RAFAEL VICUÑA<br />

tional aspects in a single definition. Obviously, this state <strong>of</strong> affairs has not<br />

stopped scientists and philosophers to confront this task, simply because the<br />

gene concept represents a central issue in the biological sciences. Somewhere<br />

in the way, investigators have advanced reasons to declare the concept<br />

<strong>of</strong> the gene dead, to be thereafter refuted with arguments showing just the<br />

opposite. 50 Fortunately, finding a univocal definition <strong>of</strong> the gene persists as<br />

an ongoing intellectual challenge, because it gives us the opportunity to<br />

witness a fascinating display <strong>of</strong> thoughts and ideas at the boundary <strong>of</strong><br />

knowledge. In the meantime, experimental molecular geneticists will continue<br />

to progress in the understanding <strong>of</strong> genome structure and expression.<br />

This situation evokes that <strong>of</strong> biology itself, in whose various branches scientists<br />

have been able to make paramount advances in spite <strong>of</strong> lacking a<br />

formal definition <strong>of</strong> living beings.<br />

50<br />

Hall, B.K. The gene is not dead, merely orphaned and seeking a home. Evol.&Dev.<br />

3:4, 225-228, 2001.<br />

<strong>21</strong>4 The Scientific Legacy <strong>of</strong> the 20 th Century

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