PASS Scripta Varia 21 - Pontifical Academy of Sciences

TABLES • A. CIECHANOVER
Figure 2: The four digestive processes mediated by the lysosome: (i) specific receptor-mediated
endocytosis, (ii) pinocytosis (non-specific engulfment of cytosolic droplets containing extracellular
fluid), (iii) phagocytosis (of extracellular particles), and (iv) autophagy (micro- and macro-;
of intracellular proteins and organelles)(with permission from Nature Publishing Group. Published
originally in Ref. 83).
372 The Scientific Legacy of the 20 th Century