Gracial ProdMonograph_cover - epgonline.org
Gracial ProdMonograph_cover - epgonline.org
Gracial ProdMonograph_cover - epgonline.org
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<strong>Gracial</strong> and mild to moderate acne<br />
<strong>Gracial</strong> has<br />
beneficial effects<br />
on mild to<br />
moderate acne<br />
These findings have been confirmed in a study by Volpe et al<br />
(1994) in which almost 80% of a group of 33 young women<br />
with acne were cured or greatly improved during 12 cycles of<br />
<strong>Gracial</strong> use.<br />
Dieben and Vromans (1994) carried out a comparative study<br />
of <strong>Gracial</strong> with a preparation containing 35 µg EE/2 mg<br />
cyproterone acetate (EE/CPA) per day and found that in both<br />
groups there was an equal reduction in degree of severity and<br />
number of acne lesions. Overall there was no statistically<br />
significant difference between the two preparations in their<br />
effects on acne (Figure 13).<br />
Mean acne grade<br />
1.0<br />
0.5<br />
0.69<br />
0.52<br />
0.54<br />
0.41<br />
0<br />
Pretreatment<br />
cycle<br />
EE/CPA<br />
Cycle 4<br />
Pretreatment<br />
cycle<br />
<strong>Gracial</strong><br />
Cycle 4<br />
Fig. 13: Effects of <strong>Gracial</strong> and EE/CPA on acne<br />
Dieben, Vromans 1994<br />
24
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