Gracial ProdMonograph_cover - epgonline.org
Gracial ProdMonograph_cover - epgonline.org
Gracial ProdMonograph_cover - epgonline.org
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Introduction<br />
<strong>Gracial</strong><br />
A recent study in 2,278 women showed specific reasons for<br />
switching from their previous OC to <strong>Gracial</strong>, as shown in the<br />
figure below (Vree 2000).<br />
Incidence (%)<br />
50<br />
40<br />
30<br />
20<br />
10<br />
0<br />
41.3%<br />
Irregular<br />
bleeding<br />
27.0%<br />
Other<br />
menstrual<br />
disorders<br />
9.8%<br />
Migraine/ Decreased<br />
headache libido<br />
3.2% 2.8% 2.7%<br />
Increased<br />
body<br />
weight<br />
Main reason for switching to <strong>Gracial</strong><br />
Fig. 2: Reasons for switching from other OCs to<br />
<strong>Gracial</strong><br />
Acne<br />
Vree 2000<br />
<strong>Gracial</strong> is a Pill which is particularly suitable for women who<br />
want to switch to a different OC because of unacceptable<br />
irregular bleeding or subjective side effects. A number of<br />
studies have also shown <strong>Gracial</strong> to have beneficial effects on<br />
mild to moderate acne.<br />
This product monograph discusses the clinical properties<br />
of <strong>Gracial</strong>, an OC preparation with a unique combiphasic<br />
regimen. The preparation contains DSG and EE in a relatively<br />
estrogenic phase during the first seven days of the Pill cycle,<br />
followed by a progestogenic phase of 15 days for the<br />
remainder of the Pill cycle.<br />
3
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