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Clinical Trials and Preclinical Infrastructure Asset Map - Life Sciences

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<strong>Clinical</strong> <strong>Trials</strong> <strong>and</strong><br />

<strong>Preclinical</strong> <strong>Infrastructure</strong><br />

<strong>Asset</strong> <strong>Map</strong><br />

Activities, Strengths, <strong>and</strong> Opportunities<br />

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It gives Genome British Columbia great pleasure to present BC’s first <strong>Clinical</strong> <strong>Trials</strong> <strong>and</strong> <strong>Preclinical</strong><br />

<strong>Infrastructure</strong> <strong>Asset</strong> <strong>Map</strong>. This document, which was developed by International BioPharma<br />

Solutions Ltd., strives to encapsulate the existing infrastructure <strong>and</strong> clinical trial activity of the<br />

last five years. The document will be used by the community to better underst<strong>and</strong> BC’s strengths<br />

<strong>and</strong> to identify new opportunities: to build upon past investments <strong>and</strong> successes <strong>and</strong> to create a<br />

world- class clinical research enterprise for the province.<br />

In order to implement this strategy, the UBC Medical School, BC Health Authorities, <strong>Life</strong> <strong>Sciences</strong><br />

BC, Michael Smith Foundation for Health Research <strong>and</strong> Genome British Columbia have collaborated<br />

<strong>and</strong> formed the British Columbia <strong>Clinical</strong> Research <strong>Infrastructure</strong> Network (BCCRIN).<br />

This network will focus on building infrastructure to support clinical research activities <strong>and</strong><br />

personnel within BC, to compete on the world stage <strong>and</strong> attract inward investment. BCCRIN will<br />

also endeavour to harmonize critical clinical research activities such as ethics, research<br />

agreements <strong>and</strong> quality systems resulting in streamlined processes <strong>and</strong> enhanced efficiencies across<br />

centres. Finally, investments in human resources, through training <strong>and</strong> development programs,<br />

will be implemented to improve the recruitment <strong>and</strong> retention of the sectors’ ‘best <strong>and</strong> brightest’.<br />

It is our hope that this asset map provides the foundation for a realistic business plan. Through the<br />

implementation of this plan it is our goal to move clinical research forward in BC - <strong>and</strong> foster an<br />

environment of collaboration which will result in increased private <strong>and</strong> public investmentbenefitting<br />

all British Columbians.<br />

BCCRIN has just appointed, Heather Harris-Harper, who comes with a wealth of 20 years clinical<br />

research experience in both industrial <strong>and</strong> academic settings.<br />

We look forward to working with the BC clinical research community to build a world-class research<br />

enterprise for BC.<br />

Pierre Meulien<br />

Chief Scientific Officer<br />

500 – 555 West 8 th Avenue, Vancouver BC V5Z 1C6 t. 604.738.8072 f. 604.738.8597 w. www.genomebc.ca


ii<br />

BRITISH COLUMBIA


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

1<br />

TABLE OF CONTENTS<br />

Executive Summary 2<br />

Introduction 4<br />

<strong>Clinical</strong> <strong>Trials</strong> <strong>Infrastructure</strong> 5<br />

Universities <strong>and</strong> Hospitals Involved in <strong>Clinical</strong> <strong>Trials</strong> 5<br />

<strong>Clinical</strong> <strong>Trials</strong> Units 6<br />

<strong>Clinical</strong> <strong>Trials</strong> Support Units 19<br />

Contract <strong>and</strong> Regulatory Support 20<br />

Quality Control/ Assurance 20<br />

Research Ethics Boards 21<br />

B.C.’s Ethics Review Structure 21<br />

Training Facilities 22<br />

Funding Sources for <strong>Clinical</strong> Research 23<br />

Industrial Funders 24<br />

Therapeutic Focus of <strong>Clinical</strong> <strong>Trials</strong> 24<br />

Types of <strong>Clinical</strong> <strong>Trials</strong> 26<br />

<strong>Clinical</strong> Investigators 28<br />

Patient Populations 29<br />

Other Public <strong>Clinical</strong> <strong>Trials</strong> Support <strong>Infrastructure</strong> 30<br />

Biorepositories 30<br />

Patient Registries 31<br />

Healthcare Research Centres 32<br />

Technology <strong>and</strong> Informatics Platforms 33<br />

Health Economics <strong>and</strong> Outcomes 33<br />

Epidemiology <strong>and</strong> Surveillance Facilities 35<br />

Biomarker Translation <strong>and</strong> Development 37<br />

Networks 37<br />

Independent Corporations Offering <strong>Clinical</strong> <strong>Trials</strong> Services 42<br />

Successes 44<br />

Organizations Offering <strong>Preclinical</strong> Services 45<br />

Comparative Positioning of B.C. Within Canada 46<br />

Opportunities for Collaboration 47<br />

Acknowledgements 48


2<br />

BRITISH COLUMBIA<br />

EXECUTIVE SUMMARY<br />

With its Province-wide single-payer government healthcare program, uniform treatment policies,<br />

ethnically diverse rapidly growing population of approximately 4.4 million people, <strong>and</strong> world class<br />

investigators, B.C. is a hot bed for clinical trials. The Province houses at least 59 clinical trials units (CTUs),<br />

centres, <strong>and</strong> study sites, as well as six clinical trials support units. All CTUs, centres, <strong>and</strong> study sites have<br />

Quality Control (QC) <strong>and</strong> Quality Assurance (QA) measures in place <strong>and</strong> work closely with the Province’s<br />

Research Ethics Boards (REBs).<br />

Over the past five years (2005/6 to 2009/10) B.C. physicians have conducted over 2,100 clinical trials,<br />

excluding investigator-initiated studies. These trials were sponsored with over $100M by industry,<br />

governments, patient groups, <strong>and</strong> other not-for-profit organizations. Sixty-two percent of the funds<br />

were obtained from 260 companies, including all of the world’s top pharmaceutical <strong>and</strong> biotech<br />

companies. This money financed 78% of the projects.<br />

<strong>Clinical</strong> trials in B.C. cover all major disease areas. The most important, based on number of studies over<br />

the past five years, are those conducted in cancer (23%). In terms of funding, clinical trials in infectious<br />

diseases/ infection receive the most money (24%). Cardiovascular/ cardiology <strong>and</strong> CNS disorders are<br />

also areas of clinical strength, accounting for 18% <strong>and</strong> 15% of individual trials <strong>and</strong> 9% <strong>and</strong> 17% of funds,<br />

respectively. Furthermore, of the Province’s 59 CTUs, centres, <strong>and</strong> study sites, 11 focus on cancer/<br />

hematology, 10 on CNS disorders, five on infectious diseases, <strong>and</strong> four on cardiology. In all disease<br />

areas, the main focus of clinical trials is drug therapies. Over the past five years 62% of all funds for<br />

single trials, <strong>and</strong> 80% of the studies, have been dedicated to pharmaceuticals.<br />

At least 560 investigators in B.C. have received funding to conduct clinical trials over the past five years,<br />

including 16 who hold endowed Chairs. The distribution of investigator expertise broadly reflects the<br />

number of clinical trials, with 127 working in cancer, 99 in cardiovascular diseases /cardiology, 85 in<br />

CNS disorders, <strong>and</strong> 48 in infectious diseases. With the largest full-service child health centre in Western<br />

Canada (B.C. Children’s Hospital) pediatrics is also an important area for clinical trials with at least 86<br />

investigators.<br />

<strong>Clinical</strong> trials have included major components in health economics, health outcomes other than<br />

response to experimental therapy, <strong>and</strong> epidemiology. Approximately 48 investigators have been<br />

involved in epidemiological aspects of clinical trials, 45 in health outcomes, <strong>and</strong> 15 in other aspects of<br />

health economics. In addition, the Province has nine health economics <strong>and</strong> health outcomes research<br />

facilities, <strong>and</strong> 13 centres that focus on epidemiology <strong>and</strong> surveillance.<br />

B.C.’s physicians have expertise in all Phases of clinical trials, from first human use studies to Phase IV.<br />

The Province’s strengths in the former are under-pinned by a number of cutting-edge technical <strong>and</strong><br />

informatics platforms, such as genomics, pharmacogenomics, proteomics, <strong>and</strong> microarrays, as well as<br />

expertise in the translation <strong>and</strong> development of biomarkers.<br />

B.C.’s physicians are also pivotal players in many national <strong>and</strong> international clinical research <strong>and</strong> trials<br />

networks, with a number of those networks based in the Province. Investigators are the founders or<br />

co-founders of the Canadian Pharmacogenomics Network for Drug Safety, the CIHR Canadian HIV


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

3<br />

<strong>Trials</strong> Network, PrioNet Canada, the SARS Accelerated Vaccine Initiative (SAVI), the Canadian Urologic<br />

Oncology Group, <strong>and</strong> various NCIC <strong>Clinical</strong> <strong>Trials</strong> Groups. These <strong>and</strong> other networks give B.C.’s<br />

investigators unsurpassed links to external experts <strong>and</strong> resources. Moreover, there are 13 Provincial<br />

healthcare-related networks that harness internal expertise <strong>and</strong> exp<strong>and</strong> the sum of the parts. Four of<br />

these are disease-based.<br />

B.C. also contains a great deal of other public infrastructure to support clinical trials. This includes<br />

comprehensive tissue databases <strong>and</strong> patient registries that are aligned with many Provincial research<br />

opportunities. Furthermore, B.C. has 24 disease-based <strong>and</strong> 14 population based (i.e., focused on<br />

children, youth, women, the elderly, aboriginals) healthcare research centres that conduct research to<br />

aid disease/ health management.<br />

As well as the public facilities described above, the Province is home to at least 25 independent<br />

organizations that offer clinical trials services, including 16 focused on clinical trials operations <strong>and</strong> five<br />

that offer analytical services. At least 21 of these organizations are home-grown companies. In addition<br />

to these clinical trials companies, B.C. has at least six major organizations offering preclinical services,<br />

including analytical services, medical device development, <strong>and</strong> preclinical drug development.<br />

The Province’s investigators <strong>and</strong> companies are keen to collaborate with companies, clinical trials<br />

networks, <strong>and</strong> other interested parties in the conduct of new clinical trials, particularly those that are<br />

research intensive (high content).


4<br />

BRITISH COLUMBIA<br />

INTRODUCTION<br />

With its Province-wide single-payer government healthcare program <strong>and</strong> resulting uniform treatment<br />

policies, B.C. is a hot bed for clinical trials. Its well-regarded teaching hospitals house many clinical<br />

opinion leaders in various therapeutic areas, particularly in cancer; conditions of the central nervous<br />

system (CNS); cardiology; cardiovascular, pulmonary <strong>and</strong> genitourinary diseases; infectious diseases;<br />

pediatrics; <strong>and</strong> transplantation.<br />

This <strong>Asset</strong> <strong>Map</strong> has been produced to facilitate new <strong>and</strong> ongoing medical product development<br />

programs managed by local, national, <strong>and</strong> international organizations. It is a snapshot of B.C.’s<br />

infrastructure <strong>and</strong> capabilities for clinical <strong>and</strong>, to a much lesser extent, preclinical studies. It includes an<br />

analysis of industry-sponsored clinical trials, as well as those funded by peer-reviewed research grants,<br />

that took place between April 2005 <strong>and</strong> March 2010.<br />

The term “clinical trials” is used here to cover the testing <strong>and</strong> evaluation of interventions <strong>and</strong> diagnostic<br />

or prognostic tests in clinical or community settings. Studies can involve the evaluation of therapeutics<br />

or vaccines, medical devices <strong>and</strong> instruments (including diagnostics <strong>and</strong> biomarkers), rehabilitation<br />

programs, <strong>and</strong>/or surgical, dietary, or psychological/ behavioural interventions in accordance with<br />

Good <strong>Clinical</strong> Practice (GCP) regulations/ guidelines. They can range from “first human use” studies<br />

(e.g., proof of concept, identification of mechanisms of pathophysiology or disease) 1 to post-marketing<br />

surveillance. Social/ behavioural studies, such as childhood development, family dynamics, youth<br />

behaviour, healthcare access, health <strong>and</strong> social services or policy, health education, health culture, <strong>and</strong><br />

health <strong>and</strong> safety are not defined as clinical trials <strong>and</strong> are not included in this report.<br />

In today’s health care environment, the socioeconomic value of novel methods within the context of<br />

the overall health care system is often included as part of clinical trials in the form of health economics<br />

(including health technology assessment <strong>and</strong>/or health outcomes research). Epidemiology studies,<br />

when combined with clinical research (new treatment options) <strong>and</strong>/ or interventions (lifestyle<br />

modification) are also included in this <strong>Asset</strong> <strong>Map</strong> as clinical trials. Furthermore, clinical studies often<br />

depend on other supporting infrastructure, such as technology <strong>and</strong> informatics expertise, health<br />

surveillance facilities, <strong>and</strong> more basic clinical research. Information on all these supporting disciplines is<br />

summarized in this report. B.C.’s wealth of research in disease etiology <strong>and</strong> the discovery <strong>and</strong> preclinical<br />

development of therapeutic interventions or diagnostics is generally excluded from this report.<br />

Information on some of this can be found in previous <strong>Asset</strong> <strong>Map</strong>s 2 .<br />

As well as clinical trials facilities, the Province is also home to a number of organizations offering<br />

preclinical services. These facilities can involve the chemical or engineering development,<br />

characterization, purification, stability, <strong>and</strong> manufacturing of new medical products; the safety <strong>and</strong><br />

efficacy testing of pharmaceuticals in nonhuman systems, such as animals <strong>and</strong> cell cultures; <strong>and</strong> the<br />

sensitivity, specificity, <strong>and</strong> reproducibility testing of devices using relevant tissues or fluids. Such tests<br />

are conducted in accordance with Good Laboratory Practice (GLP), <strong>and</strong> for manufacturing, Good<br />

Manufacturing Practice (GMP) regulations.<br />

1<br />

Also known as Experimental Medicine.<br />

2<br />

www.investbc.ca/assetmaps.htm.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

5<br />

CLINICAL TRIALS INFRASTRUCTURE<br />

Health Authorities, Hospitals, <strong>and</strong> Universities Involved in <strong>Clinical</strong> <strong>Trials</strong><br />

B.C. is covered by six health authorities 3 , five of which are involved in clinical trials. Table 1 lists the key<br />

hospitals/ agencies within these authorities involved in such studies. Many of the hospitals, particularly<br />

those within the Provincial Health Services Authority (PHSA) <strong>and</strong> Vancouver Coastal Health (VCH)<br />

provide tertiary care. The Province also has a single medical school at the University of British Columbia<br />

(UBC) (www.med.ubc.ca). This has clinical academic campuses at a number of the listed hospitals or<br />

agencies within the greater Vancouver area <strong>and</strong> Victoria (Vancouver Isl<strong>and</strong>), as well as in Prince George<br />

(Northern B.C.).<br />

TABLE 1. Health Authorities <strong>and</strong> Key Hospitals/ Agencies that Conduct <strong>Clinical</strong> <strong>Trials</strong><br />

Health Authority (URL) Key Facilities Location URL<br />

Fraser Health Authority (FHA)<br />

(www.fraserhealth.ca)<br />

Interior Health Authority (IHA)<br />

(www.interiorhealth.ca)<br />

Northern Health Authority<br />

(www.northernhealth.ca)<br />

Provincial Health Services Authority<br />

(PHSA) (www.phsa.ca)<br />

Vancouver Isl<strong>and</strong> Health Authority<br />

(VIHA) (www.viha.ca)<br />

Burnaby Hospital Burnaby www.fraserhealth.ca/find_us/locations/<br />

our_locationssite_id=1756<br />

Royal Columbian<br />

Hospital<br />

Surrey Memorial<br />

Hospital<br />

Kelowna General<br />

Hospital<br />

Penticton Regional<br />

Hospital<br />

New Westminster<br />

Surrey<br />

Kelowna<br />

Penticton<br />

www.fraserhealth.ca/find_us/locations/<br />

our_locationssite_id=1789<br />

www.fraserhealth.ca/find_us/locations/<br />

our_locationssite_id=1792<br />

www.interiorhealth.ca/health-services.<br />

aspxid=280<br />

www.interiorhealth.ca/health-services.<br />

aspxid=282<br />

Royal Inl<strong>and</strong> Hospital Kamloops www.interiorhealth.ca/health-services.<br />

aspxid=284<br />

Does not yet conduct<br />

clinical trials<br />

B.C. Cancer Agency<br />

(BCCA)<br />

B.C. Children’s<br />

Hospital (BCCH)<br />

B.C. Women’s<br />

Hospital <strong>and</strong> Health<br />

Centre<br />

Nanaimo Regional<br />

General Hospital<br />

Royal Jubilee<br />

Hospital<br />

Vancouver, Victoria,<br />

Kelowna, Surrey,<br />

Abbotsford<br />

Vancouver<br />

Vancouver<br />

Nanaimo<br />

Victoria<br />

www.bccancer.bc.ca<br />

www.bcchildrens.ca<br />

www.bcwomens.ca<br />

www.viha.ca/finding_care/facilities/nrgh.<br />

htm<br />

www.viha.ca/finding_care/facilities/royal_<br />

jubilee_hospital.htm<br />

3<br />

The Provincial Health Services Authority (PHSA), is responsible for provincial services, <strong>and</strong> five regional Authorities — Vancouver<br />

Coastal Health (VCH), Vancouver Isl<strong>and</strong> Health Authority, Fraser Health, Interior Health <strong>and</strong> Northern Health — deliver services in their<br />

respective geographic areas.


6<br />

BRITISH COLUMBIA<br />

TABLE 1. Health Authorities <strong>and</strong> Key Hospitals/ Agencies that Conduct <strong>Clinical</strong> <strong>Trials</strong> (cont’d)<br />

Health Authority (URL) Key Facilities Location URL<br />

Victoria General<br />

Hospital<br />

Victoria<br />

www.viha.ca/finding_care/facilities/victoria_general_hospital.htm<br />

Vancouver Coastal Health Authority<br />

UBC Hospital Vancouver n/a<br />

(VCH) (www.vch.ca)<br />

Vancouver General<br />

Hospital (VGH)<br />

Vancouver<br />

n/a<br />

Providence Health Care Society<br />

(Providence) 4 (www.providencehealthcare.org)<br />

St. Paul’s Hospital Vancouver www.providencehealthcare.org/info_<br />

stpauls_main.html<br />

Mount Saint Joseph<br />

Hospital<br />

Vancouver<br />

www.providencehealthcare.org/info_msj_<br />

main.html<br />

In addition, some clinical studies involve researchers (such as epidemiologists) at Simon Fraser<br />

University (SFU), UBC, the University of Victoria (UVic), <strong>and</strong> the B.C. Institute of Technology (BCIT).<br />

Furthermore, although they do not conduct clinical trials themselves, some other PHSA agencies may<br />

coordinate trials within their disease specialties: B.C. Mental Health & Addictions Services, B.C. Transplant<br />

Society, Cardiac Services B.C., Provincial Renal Agency, <strong>and</strong> Provincial Specialized Perinatal Services.<br />

<strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites<br />

B.C. has at least 59 clinical trials units (CTUs), centres 5 , study sites, <strong>and</strong> medical departments 6 that<br />

encourage clinical trials located in the hospitals <strong>and</strong> agencies listed in Table 1 7 . These are presented<br />

in Figure 1. The classification of the facilities by disease is shown in Figure 2, while a summary of<br />

each entity according to disease area can be found in Table 2. Appendix 1 contains details of each<br />

clinical trials unit, centre, <strong>and</strong> study site. Extrapolating from the responses of all 18 facilities that were<br />

interviewed in-depth specifically for this report 8 , all 59 units have the capacity <strong>and</strong> desire to conduct<br />

additional trials.<br />

A number of the facilities included in the listings are not fully fledged CTUs or <strong>Clinical</strong> <strong>Trials</strong> Centres.<br />

They generally employ study nurses or coordinators <strong>and</strong> are supported by one of the <strong>Clinical</strong> <strong>Trials</strong><br />

Support Units described below 9 . In addition, some of the Province’s smaller hospitals, such as Cowichan<br />

District, Langley Memorial, Chilliwack General, Ridge Meadows, <strong>and</strong> Vernon Jubilee, have individual<br />

investigators who perform clinical trials. These investigators are listed in Appendix 6.<br />

4<br />

Providence is an independent legal entity aligned with VCH for operational purposes.<br />

5<br />

For this report, a <strong>Clinical</strong> <strong>Trials</strong> Unit or <strong>Clinical</strong> <strong>Trials</strong> Centre has been defined as a cohesive entity with dedicated study nurses <strong>and</strong><br />

data managers. It acts as an independent management unit even if it has no dedicated space.<br />

6<br />

Medical departments that support clinical trials are, at the very least, study sites, <strong>and</strong> are often CTUs.<br />

7<br />

Note that the CTUs, centres, <strong>and</strong> study sites included here are probably not all-inclusive. The listings contain only those facilities that<br />

the authors were able to discover through extensive searches <strong>and</strong> discussions with hospital <strong>and</strong> health authority personnel.<br />

8<br />

These facilities are marked with a • in Table 2.<br />

9<br />

Although many of the facilities provide leadership in clinical trials, the way the data were collected did not generally allow a distinction<br />

between those that provided leadership <strong>and</strong> those that just provided patients (i.e., were study sites). Thus, for fairness to all the<br />

facilities, none have been tagged as leaders. The details presented in Appendix 1 provide some information of the leadership position<br />

for some centres.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

7<br />

All CTUs <strong>and</strong> <strong>Clinical</strong> Trial Centres offer:<br />

• Principal <strong>and</strong> associate investigators<br />

• Expertise in industry sponsored, investigator-initiated, <strong>and</strong> grant sponsored studies<br />

• Study nurses/ coordinators<br />

• Data managers/ coordinators<br />

• Pharmacy <strong>and</strong> laboratory staff as needed<br />

• Quality control/ assurance procedures, of which St<strong>and</strong>ard Operating Procedures (SOPs) <strong>and</strong> Good<br />

<strong>Clinical</strong> Practice (GCP) regulations <strong>and</strong> guidelines provide an integral part<br />

• Administrative services including contracts <strong>and</strong> other legal documents; budget negotiation;<br />

accounting; research ethics board (REB) submissions; regulatory documentation <strong>and</strong> coordination,<br />

including safety <strong>and</strong> other required reports.<br />

FIGURE 1. B.C.’s Hospital/Agency Based <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that<br />

Support <strong>Clinical</strong> <strong>Trials</strong><br />

PHSA<br />

Alzheimer’s Clinic<br />

Arthritis Research Centre<br />

Bladder Care Centre<br />

Cardiology/Research<br />

Centre for Ovulation &<br />

Menstrual Cycle Research<br />

Centre for Stroke &<br />

Cerebrovascular Diseases<br />

Dermatology CTU<br />

Diabetes Res. Centre<br />

Downtown ID Clinic<br />

Epilepsy Clinic<br />

Hematology Research<br />

& CTU<br />

VCHRI <strong>Clinical</strong><br />

Research Unit<br />

VCH<br />

The Lung Centre<br />

Mood Disorders Centre of<br />

Excellence CT Section<br />

Multiple Sclerosis Clinic<br />

Neurosurgery Division<br />

Pacific Parkinson’s Res.<br />

Centre<br />

The Vancouver Prostate<br />

Centre at VGH<br />

Psychiatry<br />

Administration Division<br />

Retinal Research Group<br />

Endocriminology &<br />

Metabolism<br />

Gastroenterology<br />

Nephrology Res.<br />

Unit/Group<br />

UBC Critical Care<br />

Medicine<br />

PHC<br />

AIDS Research Program<br />

CIHR Canadian HIV <strong>Trials</strong><br />

Network<br />

Emergency Medicine<br />

Res. Group<br />

Foot & Ankle Clinic<br />

Heart Centre<br />

Hematology Res. Group<br />

James Hogg iCAPTURE<br />

Centre<br />

Pacific Lung Health<br />

Centre<br />

PHCRI Centre for Health<br />

Evaluation <strong>and</strong> Outcome<br />

<strong>Sciences</strong><br />

BCCA<br />

Edward Miller <strong>Clinical</strong><br />

Research Unit<br />

Medical Oncology<br />

Vancouver Centre CTU<br />

Radiation Therapy (RT)<br />

Research Program<br />

Southern Interior CTU<br />

VIC RT Research<br />

Business Unit<br />

VIC Systemic<br />

Therapy CTU<br />

BCCH<br />

Vaccine Evaluation<br />

Centre<br />

Endocrinology<br />

& Diabetes Unit<br />

Neurosciences Program<br />

Neonatal Research Team<br />

Rheumatology Program<br />

Women & Family<br />

HIV Centre<br />

Pediatric Oncology/<br />

BMT Hematology<br />

Provincial Medical<br />

Genetics Program<br />

Pediatric Anesthesia<br />

Dept.<br />

General Surgery<br />

CFRI <strong>Clinical</strong> Research<br />

Support Unit<br />

BCWH<br />

BCCDC<br />

Labratory <strong>Clinical</strong><br />

Studies Unit<br />

FH<br />

Burnaby Hospital<br />

Regional Cancer Centre<br />

Cardiology <strong>Clinical</strong> <strong>Trials</strong><br />

Inc.<br />

Multiple Sclerosis Clinic<br />

IHA<br />

Penticton Regional<br />

Hospital Research Dept.<br />

VIHA<br />

Critical Care Group<br />

Orthopedics Dept.<br />

Ridge Meadows Hospital<br />

Dept. of Evaluation &<br />

Research Services<br />

Kidney Clinic<br />

UBC Obs&Gyn<br />

Anesthisiology Res.<br />

VIHA Research Dept.<br />

<strong>Clinical</strong> <strong>Trials</strong> Support<br />

Units<br />

CTUs/ Centres/ Sites &<br />

Depts. that Support<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Health Authorities/<br />

Agencies<br />

VCH-Vancouver Coastal Health PHC-Providence Health Care Society PHSA- Provincial Health Services Authority BCCA- B.C. Cancer Agency<br />

FH- Fraser Health Authority BCCH- B.C. Children’s Hospital BCWH- B.C. Women’s Hospital BCCDC- B.C. Centre for Disease Control<br />

IHA- Interior Health Authority VIHA- Vancouver Isl<strong>and</strong> Health Authority


8<br />

BRITISH COLUMBIA<br />

FIGURE 2. <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that Support <strong>Clinical</strong> <strong>Trials</strong> According<br />

to Disease Area<br />

Cancer/Hematology 11<br />

10<br />

5<br />

4<br />

4<br />

4<br />

CNS<br />

Infectious Disease<br />

Cardiovascular/Cardiology<br />

Genitourinary<br />

Obstetrics & Gynecology<br />

Pulmonary<br />

Metabolic/Endocrine<br />

Other Pediatric<br />

Anesthesiology<br />

Orthopedics<br />

Other<br />

2<br />

2<br />

3<br />

3<br />

3<br />

0 2 4 6 8 10 12<br />

“Other” includes arthritis, critical care, dermatology, emergency medicine, gastroenterology, medical genetics, retinal research, <strong>and</strong><br />

two multi-disease hospital research departments.<br />

Two units are included twice in this chart due to their trials focus in two conditions.<br />

10<br />

TABLE 2. <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that Support <strong>Clinical</strong> <strong>Trials</strong> by<br />

Disease Area<br />

Facility<br />

(URL if available)<br />

Anesthesiology<br />

Anesthesiology<br />

hospital departments<br />

affiliated<br />

with UBC (www.<br />

anesthesia.med.ubc.<br />

ca/cfmx/anesthesia/<br />

RCH/aboutus.cfm)<br />

Pediatric Anesthesia<br />

Department<br />

(www.bcchildrens.<br />

ca/Services/SurgeryAndSurgSuites/<br />

AnesthesiaService/<br />

default.htm)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

E.g. post-surgical<br />

pain, perioperative<br />

ischemia, postoperative<br />

thromboembolism<br />

New technology to<br />

reduce patient risk<br />

in anesthesia <strong>and</strong><br />

intensive care<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

III N/A E.g. St. Paul’s<br />

(Providence),<br />

VGH<br />

(VCH), Royal<br />

Columbian<br />

(FH))<br />

Investigators<br />

• Choi, Peter (VGH)<br />

• Cole, Colm (St.<br />

Paul’s)<br />

• Merchant,<br />

Richard (Royal<br />

Columbian)<br />

• Puil, Ernie<br />

• Warriner, Brian<br />

(VGH)<br />

Contact<br />

Cole, Colm. Head of Anesthesia,<br />

St. Paul’s Hospital.<br />

T: 604 806-8337. cole@<br />

providencehealth.bc.ca.<br />

Choi, Peter. Director<br />

of <strong>Clinical</strong> Research. T:<br />

604 875-4111 x 68433.<br />

petert.choi@vch.ca.<br />

n/a n/a BCCH (PHSA) • Ansermino, Mark Ansermino, Mark. Director<br />

of Research. T: 604-<br />

875-2711. anserminos@<br />

yahoo.ca.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

9<br />

Facility<br />

(URL if available)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

Investigators<br />

Contact<br />

Cancer/ Hematology<br />

Burnaby Hospital<br />

Regional Cancer<br />

Centre (http://<br />

research.fraserhealth.<br />

ca/clinical_trials/<br />

clinical_trials_research_groups/)<br />

Novel agents,<br />

exp<strong>and</strong>ed access,<br />

<strong>and</strong> supportive care<br />

studies<br />

II, III<br />

Sees<br />

approx.<br />

500<br />

new<br />

patients/<br />

yr<br />

Burnaby<br />

Hospital<br />

(FH)<br />

• Lam, Wendy<br />

Tkachuk, Ryan. Research<br />

Coordinator: T: 604-836-<br />

5340.<br />

tkservices@shaw.ca.<br />

Hematology Research<br />

<strong>and</strong> <strong>Clinical</strong><br />

<strong>Trials</strong> Unit (HRCTU)<br />

(www.leukemiabmtprogram.org)<br />

•<br />

All hematologic<br />

malignancies <strong>and</strong><br />

also works with stem<br />

cells<br />

I, II, III Approx.<br />

100<br />

VGH (VCH)<br />

• 12 investigators<br />

as listed in Appendix<br />

1<br />

Smith, Clay. Director<br />

Leukemia/BMT Program<br />

of B.C.<br />

T: 604-875-4863.<br />

clsmith@bccancer.bc.ca.<br />

Hematology Research<br />

Group (www.<br />

providencehealthcare.<br />

org/Dept_of_Medicine/researchers.<br />

html)<br />

Myelodysplastic<br />

syndromes,<br />

acute <strong>and</strong> chronic<br />

myeloid leukemias,<br />

chronic lymphocytic<br />

leukemia, idiopathic<br />

thrombocytopenic<br />

purpura, lymphoma<br />

in HIV patients, hemophilia,<br />

thrombosis<br />

N/A N/A St. Paul’s<br />

(Providence)<br />

5, including:<br />

• Vickars, Linda<br />

• Leitch, Heather<br />

Leitch, Heather. Director.<br />

Tel: 604 684-5794.<br />

hleitch@providencehematology.com.<br />

Centre for the<br />

Southern Interior<br />

CTU<br />

All cancer types:<br />

radiation, systemic,<br />

<strong>and</strong> palliative care<br />

I, II, III Approx.<br />

150<br />

BCCA-Centre<br />

for the<br />

Southern<br />

Interior<br />

(Kelowna)<br />

(PHSA)<br />

• 16 investigators<br />

as listed in Appendix<br />

1<br />

Broughton, S<strong>and</strong>ra<br />

Regional Administrator.<br />

T: 250-712-3903.<br />

sbroughton@bccancer.<br />

bc.ca.<br />

Edward Miller <strong>Clinical</strong><br />

Research Unit<br />

(www.bccancer.bc.ca/<br />

RS/FraserValleyCentre/research.htm)<br />

•<br />

All cancer types:<br />

radiation, systemic,<br />

<strong>and</strong> palliative care<br />

Primarily<br />

II, III;<br />

limited<br />

I; occasional<br />

70 BCCA - Fraser<br />

Valley Centre<br />

(Surrey)<br />

(PHSA)<br />

• 10 investigators<br />

as listed in Appendix<br />

1<br />

Lee, Christopher<br />

Medical Director.<br />

T: 604-930-4017.<br />

clee@bccancer.bc.ca.<br />

Medical Oncology,<br />

Vancouver Centre<br />

CTU<br />

All cancer types (especially<br />

breast, GU,<br />

lung, GI, lymphoma)<br />

0 10 , I,<br />

II, III<br />

400 BCCA-<br />

Vancouver<br />

Centre<br />

(PHSA)<br />

• 27 investigators<br />

as listed in Appendix<br />

1<br />

Chi, Kim. Director.<br />

T: 604-877-6000 x 2746.<br />

kchi@bccancer.bc.ca.<br />

10<br />

Phase 0 is a recent designation for exploratory, first-in-human trials conducted in accordance with the U.S. FDA 2006 Guidance on<br />

Exploratory Investigational New Drug (IND) Studies. Phase 0 trials are also known as human microdosing studies. Distinctive features<br />

of Phase 0 trials include the administration of single subtherapeutic doses of the study drug to a small number of subjects (10 to 15)<br />

to gather preliminary data on the agent’s pharmacokinetics <strong>and</strong> pharmacodynamics. Drug development companies carry out Phase<br />

0 studies to rank drug c<strong>and</strong>idates to take forward into further development.


10<br />

BRITISH COLUMBIA<br />

TABLE 2. <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that Support <strong>Clinical</strong> <strong>Trials</strong> by<br />

Disease Area (cont’d)<br />

Facility<br />

(URL if available)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

Investigators<br />

Contact<br />

Pediatric Oncology/<br />

BMT / Hematology<br />

Group<br />

Pediatric cancer <strong>and</strong><br />

complex blood disorders;<br />

bone marrow<br />

transplant<br />

III N/A B.C. Children’s<br />

Hospital<br />

(BCCH)<br />

(PHSA)<br />

• 7 investigators as<br />

listed in Appendix<br />

1<br />

Rogers, Paul. Medical<br />

Director.<br />

T: 604-875-2322. progers@cw.bc.ca.<br />

Radiation Therapy<br />

Research Program,<br />

Vancouver Centre<br />

(no URL)<br />

All cancers that<br />

require radiation<br />

therapy<br />

0, I, II,<br />

III, IV<br />

Approx.<br />

200<br />

BCCA –<br />

Vancouver<br />

Centre<br />

(PHSA)<br />

• 11 investigators<br />

as listed in Appendix<br />

1<br />

(1) French, John. Director<br />

of <strong>Clinical</strong> Operations.<br />

T: 604 877 6000 x 2780.<br />

JFrench2@bccancer.<br />

bc.ca.<br />

(2) Lim, Peter. Acting<br />

Professional Practice<br />

Leader - Radiation Oncology.<br />

T: 604-877-6000 x<br />

2650. plim@bccancer.<br />

bc.ca.<br />

The Vancouver<br />

Prostate Centre<br />

(also conducts genitourinary<br />

trials) (www.<br />

prostatecentre.com;<br />

www.pctriadd.com)<br />

Principally genitourinary<br />

cancers (e.g.,<br />

prostate, bladder,<br />

renal, testes)<br />

I, II, III,<br />

IV<br />

800 –<br />

1200<br />

(potential<br />

accrual)<br />

VGH (VCH)<br />

• 13 investigators<br />

as listed in Appendix<br />

1<br />

Palmer, Maureen. Study<br />

Coordinator <strong>and</strong> Nurse.<br />

T: 604-875-5675.<br />

maureen.palmer@vch.ca.<br />

Vancouver Isl<strong>and</strong><br />

Centre Radiation<br />

Therapy Research<br />

Business Unit<br />

(www.bccancer.bc.ca/<br />

RS/VancouverIsl<strong>and</strong>-<br />

Centre/research/clinicaltrials/rtrbu.htm)<br />

All cancers that<br />

involve testing of<br />

radiation therapy<br />

techniques in clinical<br />

setting<br />

I, II, III 82 –<br />

210/yr<br />

for the<br />

past 4<br />

years<br />

BCCA –<br />

Vancouver<br />

Isl<strong>and</strong> Centre<br />

(Victoria)<br />

(PHSA)<br />

• Berrang, Tanya<br />

• Pai, Howard<br />

• Truong, Pauline<br />

• Wai, Elaine<br />

1) Truong, Pauline.<br />

Radiation Oncologist. T:<br />

250 519 5500. ptruong@<br />

bccancer.bc.ca.<br />

(2) Beckham, Wayne.<br />

Head, Medical Physics.<br />

T: 250 519 5500. WBeckham@bccancer.bc.ca.<br />

VIC Systemic<br />

Therapy <strong>Clinical</strong><br />

<strong>Trials</strong> Unit (www.bccancer.bc.ca/RS/VancouverIsl<strong>and</strong>Centre/<br />

research/clinicaltrials/<br />

stctu/)<br />

All cancer types<br />

requiring systemic<br />

therapy<br />

II, III 60-75 BCCA -<br />

Vancouver<br />

Isl<strong>and</strong> Centre<br />

(Victoria)<br />

(PHSA)<br />

• 15 investigators<br />

as listed in Appendix<br />

1<br />

den Duyf, Johanna<br />

Director, Systemic<br />

Therapy <strong>and</strong> ST <strong>Clinical</strong><br />

<strong>Trials</strong> Unit.<br />

T: 250-519-5591.<br />

jdenduyf@bccancer.<br />

bc.ca.<br />

Cardiology<br />

Cardiology Research<br />

(no URL)<br />

Cardiac sciences II, III Several<br />

hundred<br />

VGH (VCH)<br />

• 14 investigators<br />

as listed in Appendix<br />

1<br />

Fox, Rebecca. Manager.<br />

T: 604-875-4065. r.fox@<br />

telus.net


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

11<br />

Facility<br />

(URL if available)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

Investigators<br />

Contact<br />

Cardiology <strong>Clinical</strong><br />

<strong>Trials</strong> Inc. (http://<br />

research.fraserhealth.<br />

ca/clinical_trials/<br />

clinical_trials_research_groups/)<br />

•<br />

James Hogg iCAP-<br />

TURE Centre (also<br />

conducts pulmonary<br />

trials) (www.icapture.<br />

ubc.ca)<br />

Heart Centre (www.<br />

heartcentre.ca)<br />

CNS<br />

Alzheimer Disease<br />

& Related Disorders’<br />

Clinic (http://<br />

ubc-alzclinic.vch.ca/<br />

index.html)<br />

B.C. Centre for<br />

Stroke <strong>and</strong> Cerebrovascular<br />

Diseases<br />

(www.bcstrokecentre.<br />

ca)<br />

Epilepsy Clinic<br />

(http://vch.eduhealth.<br />

ca/PDFs/FM/FM.470.<br />

V279.pdf)<br />

• Acute Coronary<br />

Syndromes<br />

• Congestive Heart<br />

Failure<br />

• Lipid lowering<br />

treatments<br />

• Cardiovascular<br />

disease <strong>and</strong> diabetes<br />

combined.<br />

Heart, blood vessel<br />

<strong>and</strong> lung diseases<br />

• The Healthy Heart<br />

Program<br />

• Interventional<br />

Cardiology<br />

• Atrial Fibrillation/<br />

Arrythmia Device<br />

• Cardiovascular<br />

Surgery Research<br />

• Heart Failure <strong>and</strong><br />

Acute Coronary<br />

Research<br />

Mild cognitive<br />

impairment, mild to<br />

moderate Alzheimer’s<br />

disease, use of<br />

neuroimaging<br />

Acute treatment of<br />

strokes <strong>and</strong> prevention<br />

of secondary<br />

strokes<br />

II, III, IV N/A Surrey<br />

Memorial<br />

Hospital (FH)<br />

II, III N/A St. Paul’s<br />

(Providence)<br />

I, II, III N/A St. Paul’s<br />

(Providence)<br />

II, III<br />

N/A.<br />

Sees<br />

over<br />

1,200<br />

patients/<br />

year<br />

UBC Hospital<br />

(VCH)<br />

• 8 investigators as<br />

listed in Appendix<br />

1<br />

• 13 investigators<br />

as listed in Appendix<br />

1<br />

• 25 investigators<br />

as listed in Appendix<br />

1<br />

• Feldman, Howard<br />

<strong>and</strong> five others<br />

Lynn Breakwell, RN. T:<br />

604-587-3720. lynn.<br />

breakwell@fraserhealth.<br />

ca.<br />

Hansen, Melanie.<br />

T: 604-806-9299. Melanie.Hansen@hli.ubc.ca.<br />

See www.heartcentre.<br />

ca/clinics.asp.<br />

O’Neill, Valarie. Senior<br />

<strong>Clinical</strong> Research Coordinator.<br />

T: 604-822-7990.<br />

I, II, III N/A VGH (VCH) • Teal, Philip T: 604-875-5295. teal@<br />

interchange.ubc.ca.<br />

N/A II, III N/A VGH (VCH) • Javidan, Mano<br />

• Townsend,<br />

Tiffany<br />

Javidan, Mano. Medical<br />

Director EEG Lab. T: 604<br />

875-4402. manouchehr.<br />

javidan@vch.ca.


12<br />

BRITISH COLUMBIA<br />

TABLE 2. <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that Support <strong>Clinical</strong> <strong>Trials</strong> by<br />

Disease Area (cont’d)<br />

Facility<br />

(URL if available)<br />

Mood Disorders<br />

Centre of Excellence<br />

UBC, <strong>Clinical</strong><br />

<strong>Trials</strong> Section<br />

(www.ubcmood.ca)<br />

Multiple Sclerosis<br />

Clinic (http://research.fraserhealth.<br />

ca/clinical_trials/<br />

clinical_trials_research_groups/)<br />

Multiple Sclerosis<br />

Clinic (www.<br />

ubcneurology.com/<br />

Research_MS.html)<br />

Neurosciences<br />

Program (www.bcchildrens.ca/Services/<br />

Neurosciences/ProgramsServices.htm)<br />

Neurosurgery Division<br />

(www.surgery.<br />

ubc.ca/neurosurgery)<br />

Pacific Parkinson’s<br />

Research Centre<br />

(www.parkinsons.<br />

ubc.ca/index.html)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Mood disorders<br />

(particularly depression<br />

<strong>and</strong> bipolar<br />

disorders)<br />

Therapeutic trials<br />

for MS<br />

Therapeutic trials<br />

for MS<br />

Pediatric trials in<br />

neurology, neuromuscular<br />

diseases.<br />

Cerebrovascular<br />

disease/ stroke<br />

Diagnosis <strong>and</strong><br />

management of<br />

Parkinson’s <strong>and</strong> other<br />

related disorders,<br />

such as tremor <strong>and</strong><br />

dystonia, using novel<br />

drugs, surgery, <strong>and</strong><br />

neuroimaging<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

I, II, III,<br />

IV<br />

II, III<br />

II, III<br />

Annual<br />

Patient<br />

Accrual<br />

Over<br />

100<br />

N/A.<br />

Clinic<br />

has<br />

3,000<br />

patients<br />

N/A.<br />

Over<br />

600<br />

new<br />

patients/<br />

yr<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

UBC Hospital<br />

(VCH)<br />

Burnaby<br />

Hospital<br />

(FH)<br />

UBC Hospital<br />

(VCH)<br />

Investigators<br />

• 16 investigators<br />

as listed in Appendix<br />

1<br />

• Vorobeychik,<br />

Galina<br />

• 7 investigators as<br />

listed in Appendix<br />

1<br />

Contact<br />

Woo, Cindy. Research<br />

Coordinator. T: 604-822-<br />

7627.<br />

cinw@interchange.ubc.<br />

ca.<br />

Vorobeychik, Galina.<br />

Principal Investigator<br />

<strong>and</strong> Clinic Director. T: 604<br />

412-6405.<br />

galina.vorobeychik@<br />

fraserhealth.ca.<br />

Traboulsee, A. Head of<br />

<strong>Clinical</strong> <strong>Trials</strong> Group. T:<br />

604 822-0788. trabouls@<br />

interchange.ubc.ca.<br />

N/A N/A BCCH (PHSA) • N/A Farrell, Kevin, <strong>Clinical</strong><br />

Neurologist. T: 604-875-<br />

2976. kfarrell@cw.bc.ca.<br />

II, III<br />

I, II, III,<br />

IV<br />

Approx.<br />

200<br />

may be<br />

eligible<br />

for<br />

clinical<br />

trials<br />

N/A<br />

VGH (VCH)<br />

UBC Hospital<br />

(VCH)<br />

• Haw, Charles<br />

• Heran, Manraj<br />

• Redekop, Gary<br />

• McKeown,<br />

Martin J.<br />

• Stoessl, Jonathan<br />

• Tsui, Joseph<br />

Redekop, Gary. Head,<br />

Division of Neurosurgery.<br />

T: 604-875-5235.<br />

gary.redekop@vch.ca.<br />

Babul, Shamin. Administrator.<br />

T: 604-822-7721.<br />

ndsb@interchange.<br />

ubc.ca


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

13<br />

Facility<br />

(URL if available)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

Investigators<br />

Contact<br />

Psychiatry Administration<br />

Division<br />

(no URL)<br />

Mental illness, particularly<br />

depression,<br />

schizophrenia, <strong>and</strong><br />

addiction<br />

III, IV<br />

Sees<br />

approx.<br />

500<br />

new<br />

patients/<br />

year<br />

VGH (VCH)<br />

• Ganesan, Soma<br />

• Lu, Shaohua<br />

• Mok, HIram<br />

• Singh, Kulbir<br />

Ganesan, Soma. T:<br />

604-875-4023. soma.<br />

ganesan@vch.ca.<br />

Genitourinary<br />

Bladder Care Centre<br />

(http://urology.ubc.<br />

ca/bladder-carecentre)<br />

Investigation of<br />

medicines, <strong>and</strong><br />

naturopathic <strong>and</strong><br />

complementary<br />

therapies<br />

N/A N/A UBC Hospital<br />

(VCH)<br />

• Stothers, Lynn<br />

Stothers, Lynn. Director<br />

of Research. T: 604-822-<br />

7616. lynns@interchange.ubc.ca.<br />

Nephrology<br />

Research Unit, associated<br />

with the<br />

B.C. Renal Agency<br />

(www.bcrenalagency.<br />

ca/)<br />

Chronic kidney disease,<br />

dialysis, kidney<br />

transplantation<br />

II, III, IV 800<br />

(potential<br />

accrual)<br />

VGH (VCH)<br />

<strong>and</strong> St Paul’s<br />

Hospital<br />

(Providence);<br />

B.C. Renal<br />

Agency<br />

(PHSA)<br />

• 18 investigators<br />

as listed in Appendix<br />

1<br />

Rogers, Daniel. UBC<br />

Division of Nephrology,<br />

<strong>Clinical</strong> Research<br />

Manager VGH.<br />

T. 604-875-4111x 67679.<br />

Daniel.rogers@vch.ca.<br />

The Vancouver<br />

Prostate Centre<br />

See above under<br />

“Cancer” for details<br />

Kidney Clinic (www.<br />

bcrenalagency.ca/<br />

kidneysvcs/Kidney-<br />

ServicesRegion/<br />

InteriorHealth/chronicClinics.htm)<br />

Dialysis, end stage<br />

renal disease<br />

III N/A Royal Inl<strong>and</strong><br />

Hospital<br />

(IHA)<br />

• Wijeyesinghe,<br />

ECR.<br />

Pennington, Carrie Mae.<br />

Manager. T: 250-314-<br />

2849.<br />

Infectious Diseases<br />

AIDS Research<br />

Program (www.<br />

cfenet.ubc.ca/content.<br />

phpid=18)<br />

HIV, Hepatitis C Virus<br />

(HCV) – HIV coinfection,<br />

<strong>and</strong> fungal<br />

infection<br />

II, III, IV 100 -<br />

200<br />

St Paul’s<br />

(Providence)<br />

• Montaner, Julio<br />

• Barrios, Rol<strong>and</strong>o<br />

• Guillemi, Silvia<br />

• Phillips, Peter<br />

• Tyndall, Mark<br />

Chau, William<br />

T: 604-806-8064.<br />

wchau@cfenet.ubc.ca.<br />

CIHR Canadian<br />

HIV <strong>Trials</strong> Network<br />

(www.hivnet.ubc.ca)<br />

HIV <strong>and</strong> related<br />

diseases<br />

II, III, IV<br />

417 in<br />

2008/9<br />

St. Paul’s<br />

(Providence)<br />

• Schechter, Martin<br />

• Anis, Aslam<br />

Pankovich, Jim.<br />

Chief Scientific Officer.<br />

T: 604-806-8340.<br />

jpankovich@mail.hivnet.<br />

ubc.ca.


14<br />

BRITISH COLUMBIA<br />

TABLE 2. <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that Support <strong>Clinical</strong> <strong>Trials</strong> by<br />

Disease Area (cont’d)<br />

Facility<br />

(URL if available)<br />

Downtown Infectious<br />

Diseases Clinic<br />

(no URL)<br />

Vaccine Evaluation<br />

Centre CTU<br />

(www.bcchildrens.<br />

ca/Research/Vaccine-<br />

EvaluationCentre)<br />

Women & Family<br />

HIV Centre (no URL)<br />

Pulmonary<br />

James Hogg iCAP-<br />

TURE Centre<br />

Pacific Lung Centre<br />

(www.pacificlung.<br />

com)<br />

The Lung Centre<br />

(http://lungcentre.<br />

vch.ca/)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

Investigators<br />

Mainly HIV <strong>and</strong> HCV II, III, IV 40 VGH (VCH) • Conway, Brian<br />

• Alenezi, Osamah<br />

• Reynolds, Robert<br />

Various infectious<br />

diseases<br />

Therapy, vaccines,<br />

<strong>and</strong> diagnostic/<br />

prognostic biomarkers<br />

in pregnant<br />

women, infants,<br />

children, <strong>and</strong> youth<br />

See above under<br />

“Cardiology” for<br />

details<br />

E.g. chronic obstructive<br />

pulmonary<br />

disease (bronchitis<br />

<strong>and</strong> emphysema),<br />

interstitial pulmonary<br />

fibrosis, chronic<br />

cough, cystic fibrosis,<br />

asthma<br />

E.g., asthma,<br />

emphysema,<br />

chronic bronchitis,<br />

bronchiectasis, lung<br />

cancer, occupational<br />

<strong>and</strong> environmental<br />

lung diseases, sarcoidosis,<br />

pnuemonia,<br />

tuberculosis, pulmonary<br />

hypertension<br />

<strong>and</strong> interstitial lung<br />

disease<br />

II, III, IV<br />

Not<br />

applicable<br />

BCCH (PHSA)<br />

• Scheifele, David<br />

• Dobson, Simon<br />

• Kollmann, Tobias<br />

• Bettinger, Julie<br />

• Sauve, Laura<br />

N/A N/A BCCH (PHSA) • Burdge, David<br />

• Forbes, John<br />

(Jack)<br />

II, III, IV N/A St Paul’s<br />

(Providence)<br />

• 11 investigators<br />

as listed in Appendix<br />

1<br />

II, III, IV 140 VGH (VCH) • 16 investigators<br />

as listed in Appendix<br />

1<br />

Contact<br />

Tossonian, Harout.<br />

Research Manager. T:<br />

604-642-6429 x 304.<br />

tossonian@exchange.<br />

ubc.ca.<br />

Bjornson, Gordean.<br />

T: 604-875-2422. gbjornson@cw.bc.ca.<br />

Forbes, John (Jack).<br />

Medical Director. T:<br />

604-875-2212. jforbes@<br />

cw.bc.ca.<br />

Tel: 604 806-9465. info@<br />

pacificlung.com.<br />

Tom, Freda. <strong>Clinical</strong> <strong>Trials</strong><br />

Coordinator.<br />

T: 604-875-4111 x<br />

67916.<br />

Freda.Tom@vch.ca.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

15<br />

Facility<br />

(URL if available)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Metabolic-Endocrine<br />

Diabetes Research<br />

Centre (http://diabetesresearch.net/)<br />

Endocrinology <strong>and</strong><br />

Diabetes Unit<br />

Endocrinology <strong>and</strong><br />

Metabolism (no<br />

URL)<br />

Novel drugs for<br />

diabetes, diabetes<br />

<strong>and</strong> cardiovascular<br />

disease<br />

Drug therapy <strong>and</strong><br />

biomarkers in pediatric<br />

patients<br />

Neuroendocrine<br />

disorders, diabetes,<br />

dyslipidemia, <strong>and</strong><br />

obesity<br />

Obstetrics & Gynecology<br />

Maternal Fetal<br />

Medicine Research<br />

Unit (no URL)<br />

Obstetrics <strong>and</strong><br />

Gynecology hospital<br />

departments<br />

affiliated with UBC<br />

(www.obstgyn.ca)<br />

Obstetrics Medicine<br />

Program (http://<br />

www.bcwomens.ca/<br />

ForProfessionals/<strong>Clinical</strong>Practice/SpecializedWomensHealth/<br />

Obstetric+Medicine.<br />

htm<br />

Centre for Menstrual<br />

Cycle <strong>and</strong><br />

Ovulation Research<br />

(www.cemcor.ubc.ca)<br />

Drug therapy; biomarkers;<br />

management<br />

of labour <strong>and</strong><br />

delivery, technology<br />

assessment<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

Investigators<br />

Contact<br />

III + N/A VGH (VCH) • Elliott, Tom Elliott, Tom. T: 604-875-<br />

5934. tom.elliott@vch.<br />

ca.<br />

N/A N/A BCCH (PHSA) • Amed, Shazhan<br />

• Chanoine, Jean-<br />

Pierre<br />

• Metzger, Daniel<br />

•Panagiotopoulos,<br />

Constadina<br />

II, III N/A VGH (VCH)<br />

<strong>and</strong> St Paul’s<br />

(Providence)<br />

N/A N/A B.C. Women’s<br />

Hospital<br />

(PHSA)<br />

N/A II, III N/A E.g. B.C.<br />

Women’s<br />

Hospital<br />

(PHSA), St.<br />

Paul’s (Providence),<br />

VGH<br />

(VCH), Royal<br />

Columbian<br />

(FH)<br />

Hypertensive disorders<br />

of pregnancy<br />

<strong>and</strong> diabetes<br />

Ovulation <strong>and</strong> the<br />

causes for <strong>and</strong> consequences<br />

of ovulation<br />

disturbances<br />

N/A N/A BCWH<br />

(PHSA)<br />

• Elliott, Tom<br />

• Sirrs, S<strong>and</strong>ra<br />

• Ur, Ehud<br />

• 13 investigators<br />

as listed in Appendix<br />

1<br />

• At least 18 investigators<br />

as listed in<br />

Appendix 1<br />

• Liston, Rob<br />

• Magee, Laura<br />

• Thompson, David<br />

Chanoine, Jean-Pierre.<br />

Head, Division of Pediatric<br />

Endocrinology. T: 604-<br />

875-2624. jchanoine@<br />

cw.bc.ca.<br />

Ur, Ehud. Division Head.<br />

T: 604 875-4552. ehud.<br />

ur@vch.ca<br />

Alain Gagnon. agagnon@<br />

cw.bc.ca.<br />

Fern<strong>and</strong>ez, Ariadne. Research<br />

Program Manager.<br />

afern<strong>and</strong>ez@phsa.ca.<br />

Magee, Laura. Senior<br />

Clinician Scientist. T: 604-<br />

875-2424 ext. 6012.<br />

lmagee@cw.bc.ca. .<br />

IV N/A VGH (VCH) • Prior, Jerilynn C. T: 604–875-5927. cemcor@interchange.ubc.ca


16<br />

BRITISH COLUMBIA<br />

TABLE 2. <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that Support <strong>Clinical</strong> <strong>Trials</strong> by<br />

Disease Area (cont’d)<br />

Facility<br />

(URL if available)<br />

Orthopedics<br />

Foot <strong>and</strong> Ankle<br />

Clinic Orthopedics<br />

Research Group<br />

(www.bcfoot<strong>and</strong>ankle.com)<br />

Orthopedics<br />

Department (http://<br />

research.fraserhealth.<br />

ca/clinical_trials/<br />

clinical_trials_research_groups/)<br />

Other Pediatric<br />

Neonatal Research<br />

Program (no URL)<br />

Pediatric General<br />

Surgery (www.bcchildrens.ca/Services/<br />

SurgeryAndSurg-<br />

Suites/GeneralSurgery/default.htm)<br />

Pediatric Rheumatology<br />

Program<br />

(www.bcchildrens.ca/<br />

Services/Specialized-<br />

Pediatrics/Rheumatology/default.htm)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Surgical techniques<br />

used to treat a<br />

variety of foot <strong>and</strong><br />

ankle ailments<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

I, II, III N/A St Paul’s<br />

Hospital<br />

(Providence)<br />

N/A II, III N/A Royal<br />

Columbian<br />

Hospital<br />

(FH)<br />

Effects of nutrition,<br />

oxidants, <strong>and</strong> antioxidants<br />

on biological<br />

markers <strong>and</strong> clinical<br />

outcome; stress/<br />

pain; role of immunity<br />

<strong>and</strong> genetics<br />

in neonatal disease;<br />

brain development<br />

<strong>and</strong> injury; neonatal<br />

ventilation; critical<br />

care therapies<br />

Fetal therapies,<br />

including gene<br />

replacement;<br />

outcomes<br />

Pediatric rheumatic<br />

diseases including<br />

chronic arthritis,<br />

systemic lupus<br />

erythematosus <strong>and</strong><br />

vasculitis<br />

I, II, III,<br />

IV<br />

Approx.<br />

700<br />

admissions/<br />

year<br />

BCCH (PHSA)<br />

Investigators<br />

• Younger, Alastair<br />

• Yang, Tung Chuo<br />

•Smith, Donna<br />

• McCormack,<br />

Robert<br />

• Perey, Bertr<strong>and</strong><br />

• Stone, Trevor<br />

• Chessex, Philippe<br />

(Head)<br />

• 12 others listed<br />

in Appendix 1<br />

Contact<br />

Bora, Biraj. <strong>Clinical</strong><br />

Research Coordinator. T:<br />

604-806-8743.<br />

Mauri Zomar, Research<br />

Coordinator,<br />

T: 604-520-4855. Mauri.<br />

Zomar@fraserhealth.ca.<br />

Claydon, Jennifer<br />

Research Program<br />

Manager.<br />

T: 604-875-2000 x 7408.<br />

jclaydon@cw.bc.ca.<br />

N/A N/A BCCH (PHSA) • Skarsgard, Erik Skarsgard, Erik. Head,<br />

Division of Pediatric<br />

General Surgery.<br />

T: 604-875-3744. eskarsgard@cw.bc.ca.<br />

N/A N/A BCCH (PHSA) • Cabral, David<br />

• Petty, Ross<br />

• Tucker, Lori<br />

Cabral, David. Director of<br />

Young Adult Rheumatic<br />

Disease (YARD) Clinic. T:<br />

604-875-2437. dcabral@<br />

cw.bc.ca.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

17<br />

Facility<br />

(URL if available)<br />

Other<br />

Arthritis Research<br />

Centre<br />

Critical Care<br />

Medicine hospital<br />

departments<br />

affiliated with UBC<br />

(www.ubccriticalcaremedicine.ca)<br />

(see below for Fraser<br />

Health group)<br />

Critical Care Group<br />

Fraser Health<br />

(http://research.<br />

fraserhealth.ca/<br />

clinical_trials/clinical_trials_research_<br />

groups/)<br />

Dermatology<br />

<strong>Clinical</strong> <strong>Trials</strong> Unit<br />

(www.derm.ubc.ca/<br />

research/clinical_trials_unit.htm)<br />

Emergency<br />

Medicine Research<br />

Group (www.<br />

sphemerg.ca/research)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Arthritis diagnosis,<br />

prognosis, prevention,<br />

care outcomes,<br />

<strong>and</strong> quality of life<br />

issues<br />

Sepsis <strong>and</strong> septic<br />

shock, prevention of<br />

thromboembolism,<br />

ARDS <strong>and</strong> other<br />

inflammatory lung<br />

diseases, apnea,<br />

<strong>and</strong> traumatic brain<br />

injury<br />

Thromboprophylaxis;<br />

ARDS; sedation<br />

management, life<br />

support outcomes<br />

for octogenarians;<br />

ventilator associated<br />

pneumonia; H1N1;<br />

sepsis; acute lung<br />

injury; antibiotics<br />

All areas of dermatology,<br />

including<br />

acne, psoriasis,<br />

eczema, warts, skin<br />

cancer, <strong>and</strong> hair<br />

disorders<br />

Infectious diseases<br />

(SSTI, Sepsis), Stroke<br />

Care, Patient Safety<br />

<strong>and</strong> Medical Decision<br />

Making<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

Investigators<br />

Contact<br />

N/A N/A VCH N/A Ellis, Nancy. Senior <strong>Clinical</strong><br />

<strong>Trials</strong> Coordinator. T:<br />

604-871-4573.<br />

II, III N/A e.g. St. Paul’s<br />

(Providence),<br />

VGH<br />

(VCH), B.C.<br />

Children’s<br />

Hospital<br />

(PHSA),<br />

Royal<br />

Columbian<br />

(FH), Surrey<br />

Memorial<br />

Hospital (FH)<br />

II, III N/A Royal<br />

Columbian<br />

(FH), Surrey<br />

Memorial<br />

Hospital (FH)<br />

I, II, III,<br />

IV<br />

N/A<br />

VGH/ UBC<br />

(VCH)<br />

III N/A St. Paul’s<br />

(Providence)<br />

• 10 investigators<br />

as listed in Appendix<br />

1<br />

• Reynolds, Steven<br />

• Keenan, Sean<br />

• 9 investigators as<br />

listed in Appendix<br />

1<br />

• Grafstein, Eric<br />

• Harris, Devin<br />

• Stenstrom,<br />

Robert<br />

Dhingra, Vinay. T: 604<br />

875-5949. vinay.dhingra@vch.ca.<br />

S vetik, Miroslav. ICU<br />

RCH Research Coordinator.<br />

miroslav.svetik@<br />

fraserhealth.ca.<br />

Sheilagh Mans, ICU SMH<br />

Research Coordinator.<br />

Sheilagh.Mans@fraserhealth.ca<br />

Lui, Harvey.<br />

T: 604 875-4747. harvey.<br />

lui@ubc.ca<br />

Stenstrom, Robert.<br />

Research Director. Tel:<br />

604-682-2344 x 68985.<br />

robstenstrom@shaw.ca.


18<br />

BRITISH COLUMBIA<br />

TABLE 2. <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites that Support <strong>Clinical</strong> <strong>Trials</strong> by<br />

Disease Area (cont’d)<br />

Facility<br />

(URL if available)<br />

Gastroenterology<br />

(no URL)<br />

Penticton Regional<br />

Hospital Research<br />

Department (No<br />

URL)<br />

Provincial Medical<br />

Genetics Program<br />

(www.bcchildrens.ca/<br />

Services/MedicalGenetics/default.htm)<br />

Ridge Meadows<br />

Hospital (http://<br />

research.fraserhealth.<br />

ca/clinical_trials/<br />

clinical_trials_research_groups/)<br />

Vancouver Retinal<br />

Research Group (No<br />

URL) •<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Disease Focus<br />

Colitis, Crohn’s,<br />

liver disease (e.g.,<br />

hepatitis, cancer),<br />

GERD <strong>and</strong> erosive<br />

esophagitis, motility<br />

Cardiology, Neurology,<br />

Nephrology,<br />

Gynecology,<br />

Pediatrics, Oncology,<br />

Rheumatology<br />

Identification <strong>and</strong><br />

experimental treatment<br />

of lysosomal<br />

storage diseases<br />

Cardiac research,<br />

antibiotics in<br />

pneumonia, asthma<br />

<strong>and</strong> COPD<br />

Macular degeneration,<br />

diabetic<br />

retinopathy, <strong>and</strong><br />

central retina vein<br />

occlusion<br />

Types<br />

of<br />

<strong>Trials</strong>*<br />

Annual<br />

Patient<br />

Accrual<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority)*<br />

II, III N/A VGH (VCH),<br />

St Paul’s<br />

(Providence)<br />

III, IV N/A Penticton<br />

Regional<br />

Hospital<br />

(IHA)<br />

Investigators<br />

• 6 investigators as<br />

listed in Appendix<br />

1<br />

• 9 investigators as<br />

listed in Appendix<br />

1<br />

Contact<br />

Byrne, Michael. T: 604<br />

875-5640. michael.<br />

byrne@vch.ca<br />

Susan Valley, Coordinator<br />

<strong>Clinical</strong> Research.<br />

T: 250-492-4000 x 2629.<br />

Susan.Valley@interiorhealth.ca.<br />

N/A N/A BCCH (PHSA) • N/A Clarke, Lorne. T: 604-875-<br />

2157. lclarke@cw.bc.ca.<br />

III N/A Ridge Meadows<br />

Hospital<br />

(FH)<br />

II, III N/A VGH/ UBC<br />

Eye Care<br />

Centre (VCH)<br />

• Auersperg,<br />

Edward<br />

• Ervin, Frank<br />

• Tsui, Winston<br />

• Albiani, David<br />

• Merkur, Andrew<br />

• Potter, Michael<br />

Ervin, Frank. T: 604-466-<br />

8199. flervin@telus.net.<br />

Gillies, Dawne. <strong>Clinical</strong><br />

Research Coordinator.<br />

T: 604-875-4253.<br />

dawne.gillies@vch.ca<br />

N/A = Not available<br />

• BioPharma Solutions conducted an in-depth review of these facilities including visits <strong>and</strong> interviews.<br />

• Hospitals/ Agencies: BCCA = B.C. Cancer Agency (www.bccancer.bc.ca); BCCH = B.C. Children’s Hospital (www.bcchildrens.ca); VGH<br />

= Vancouver General Hospital; Health Authorities: FH = Fraser Health Authority (www.fraserhealth.ca; http://research.fraserhealth.<br />

ca/); PHSA = Provincial Health Services Authority (www.phsa.ca); Providence = Providence Health Care Society (www.providencehealthcare.org);<br />

VCH = Vancouver Coastal Health Authority (www.vch.ca); IHA = Interior Health Authority (www.interiorhealth.ca).<br />

* Most, if not all, units also conduct investigator-initiated, cooperative research group, <strong>and</strong> grant sponsored studies.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

19<br />

<strong>Clinical</strong> <strong>Trials</strong> Support Units<br />

The health authorities have five clinical trials support units to aid individual investigators in their clinical<br />

trials. These are shown in Figure 1, summarized in Table 3, <strong>and</strong> described in Appendix 2. The units generally<br />

offer the following services:<br />

• Study design, methodology, <strong>and</strong> protocol development<br />

• Budget planning <strong>and</strong>/or review<br />

• Assistance with REB submission<br />

• Regulatory documentation<br />

• Statistical analysis <strong>and</strong> data management<br />

• Training in clinical trials procedures <strong>and</strong> GCP<br />

• Pharmacoeconomic analysis (at Vancouver Coastal Health Research Institute [VCHRI] [through<br />

the Centre for <strong>Clinical</strong> Epidemiology & Evaluation] <strong>and</strong> Providence Health Care Research Institute<br />

[through the Centre for Health Evaluation <strong>and</strong> Outcome <strong>Sciences</strong>])<br />

• Provision of trained nurses (at Child & Family Research Institute [CFRI] <strong>and</strong> VCHRI)<br />

• Provision of study/ clinic space (at CFRI, VCHRI <strong>and</strong> VIHA Research Department).<br />

In addition, the Laboratory-<strong>Clinical</strong> Studies Unit at the B.C. Centre for Disease Control (BCCDC) provides<br />

laboratory support <strong>and</strong> testing for clinical trials.<br />

TABLE 3. <strong>Clinical</strong> <strong>Trials</strong> Support Units<br />

Facility (URL if available)<br />

Types of<br />

<strong>Trials</strong> *<br />

CFRI <strong>Clinical</strong> Research Support<br />

Unit (www.cfri.ca/research_support/clinical_research_support/<br />

default.asp)<br />

Department of Evaluation <strong>and</strong><br />

Research Services<br />

(http://research.fraserhealth.ca/)<br />

Laboratory-<strong>Clinical</strong> Studies Unit<br />

(www.phsa.ca/bccdcpublichealthlab)<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority) *<br />

Investigators<br />

I, II, III, IV BCCH (PHSA) • Supports all<br />

CFRI clinical<br />

investigators<br />

II, III, IV plus<br />

screening,<br />

diagnostic,<br />

observational,<br />

interventional<br />

studies<br />

II, III, IV plus<br />

screening,<br />

diagnostic,<br />

observational,<br />

interventional<br />

studies<br />

mainly in<br />

HPV, HIV,<br />

Hepatitis<br />

Fraser Health<br />

(FH)<br />

BCCDC, PHSA<br />

• Supports all<br />

active FH clinical<br />

investigators<br />

• Mel Krajden<br />

• Petric, Martin<br />

Contact<br />

Junker, Anne. Director, <strong>Clinical</strong> & Population<br />

Health Studies, CFRI.<br />

T: 604-875-3591<br />

ajunker@cw.bc.ca<br />

Susan Chunick, Director, Department of<br />

Evaluation <strong>and</strong> Research Services.<br />

T: 604-587-4681<br />

susan.chunick@fraserhealth.ca<br />

Krajden, Mel. Associate Director, Laboratory<br />

Services.<br />

T: 604-707-2421.<br />

mel.krajden@bccdc.ca.


20<br />

BRITISH COLUMBIA<br />

TABLE 3. <strong>Clinical</strong> <strong>Trials</strong> Support Units (cont’d)<br />

Facility (URL if available)<br />

PHCRI <strong>and</strong> the Centre for Health<br />

Evaluation <strong>and</strong> Outcome <strong>Sciences</strong><br />

(www.cheos.ubc.ca)<br />

VCHRI <strong>Clinical</strong> Research Unit<br />

(www.vchri.ca/s/CRU.asp)<br />

VIHA Research Department<br />

(www.viha.ca/rnd/)<br />

Types of<br />

<strong>Trials</strong> *<br />

II, III, IV<br />

II, III, IV<br />

II, III, IV<br />

Hospital/<br />

Agency<br />

(Health<br />

Authority) *<br />

St. Paul’s (Providence)<br />

Institutes <strong>and</strong><br />

communities<br />

within VCH,<br />

including VG,<br />

UBC, Lion’s Gate<br />

<strong>and</strong> Richmond<br />

hospitals<br />

Hospitals within<br />

the VIHA<br />

Investigators<br />

• 45 affiliated<br />

clinical investigators<br />

• Supports all<br />

PIs at VGH, UBC<br />

<strong>and</strong> other VCH<br />

hospitals <strong>and</strong><br />

clinics<br />

• Supports<br />

30 clinical<br />

investigators<br />

at Vancouver<br />

Isl<strong>and</strong> hospitals<br />

* Also support investigator-initiated, cooperative research group, <strong>and</strong> grant sponsored studies.<br />

Contact<br />

Orr, John. Director of Operations<br />

T: 604-806-2294<br />

johnorr@mail.cheos.ubc.ca<br />

Feschuk, Connie. Manager.<br />

T: 604-875-5886. connie.feschuk@<br />

vch.ca<br />

Patel, Anika. Acting Regional Manager.<br />

T: 250-370-8764<br />

anika.patel@viha.ca.<br />

Contract <strong>and</strong> Regulatory Support<br />

As indicated in Appendices 1 <strong>and</strong> 2, individual CTUs, centres, study sites, <strong>and</strong> <strong>Clinical</strong> <strong>Trials</strong> Support<br />

Units employ study nurses <strong>and</strong> other staff who liaise between sponsors <strong>and</strong> services that provide<br />

expertise in negotiating <strong>and</strong> developing contracts. For clinical trials facilities affiliated with VCH, Providence,<br />

BCCH, B.C. Women’s Hospital, <strong>and</strong> Fraser Health, the expert facility is the UBC University-Industry<br />

Liaison Office (www.uilo.ubc.ca). For BCCA CTUs <strong>and</strong> centres, services are provided by the Technology<br />

Development Office (www.bccancer.bc.ca). A number of the investigators on Vancouver Isl<strong>and</strong> use<br />

the services of the VIHA Research Department (www.viha.ca/rnd/); otherwise, contracts are generally<br />

h<strong>and</strong>led in-house or by other external facilities. The majority of sites, if not all, provide support for REB<br />

submissions <strong>and</strong> regulatory documentation to, <strong>and</strong> coordination with, Health Canada <strong>and</strong> the U.S. Food<br />

<strong>and</strong> Drug Administration (FDA).<br />

Quality Control/ Assurance<br />

All B.C.’s CTUs, centres, <strong>and</strong> study sites have Quality Control (QC) <strong>and</strong> Quality Assurance (QA) measures<br />

in place, as indicated in Appendices 1 <strong>and</strong> 3.<br />

St<strong>and</strong>ard Operating Procedures (SOPs) comprise an integral part of each unit’s quality systems. SOPs<br />

cover study-related functions (including consent, collection of blood <strong>and</strong> other biological samples, data<br />

management, confidentiality, reporting <strong>and</strong> management of adverse events, study termination/ closure,<br />

<strong>and</strong> archiving), responsibilities, <strong>and</strong> training requirements. In the absence of SOPs, facilities ensure<br />

st<strong>and</strong>ardization by the use of other documents, such as checklists, or closely follow in-house guidelines.<br />

As required for clinical trials, SOPs or in-house guidelines are compliant with Health Canada, .FDA.), <strong>and</strong><br />

ICH Good <strong>Clinical</strong> Practices (GCP) regulations <strong>and</strong> guidelines. Quality is also assured by the fact that<br />

all staff <strong>and</strong> investigators are trained in their site-specific SOPs as well as GCP. Furthermore, all projects<br />

have to be approved by stringent REBs prior to initiation.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

21<br />

There is generally no requirement for st<strong>and</strong>ardized SOPs within a health authority or hospital. However,<br />

CTUs affiliated with the BCCA follow that agency’s SOPs. For industry sponsored trials, the sponsor generally<br />

provides a procedures manual specific to the study under investigation.<br />

QA annual audits are generally conducted for the REB <strong>and</strong>/or the clinical facility. For industry sponsored<br />

trials, audits are conducted by the study sponsor <strong>and</strong> may also be conducted by regulatory authorities.<br />

In addition, the UBC Office of Research Services, which manages the ethics review process for hospitals<br />

affiliated with UBC (see below), conducts internal reviews of r<strong>and</strong>omly selected studies that have<br />

received REB approval.<br />

Research Ethics Boards 11<br />

Regulatory Guidelines Followed by Research Ethics Boards in B.C.<br />

The responsibility for ethics in research involving human subjects in B.C. lies primarily with institutional<br />

REBs that follow <strong>and</strong> interpret sets of international <strong>and</strong> national guidelines, codes of ethics or policy<br />

statements to protect human subjects through risk/benefit evaluation, assurance of informed consent,<br />

<strong>and</strong> monitoring of ongoing studies 12 . Investigators intending to conduct human subject research in B.C.<br />

must seek REB approval from the involved institution(s) to satisfy funding <strong>and</strong> regulatory requirements,<br />

institutional policy requirements, <strong>and</strong> to meet criteria for publication in peer-reviewed journals. The<br />

1998 Tri-Council 13 Policy Statement (TCPS): “Ethical Conduct for Research Involving Humans” established<br />

ethical principles as well as requirements <strong>and</strong> prohibitions for REBs in Canada. The TCPS is widely accepted<br />

as the gold st<strong>and</strong>ard to which Canadian REBs aspire for ensuring efficiency <strong>and</strong> fairness to both<br />

human subjects <strong>and</strong> researchers.<br />

In 2006, B.C. REBs reviewed a total of 13,593 research protocols, including 4,465 new applications, 6,473<br />

amendments, <strong>and</strong> 2,655 renewals.<br />

B.C.’s Ethics Review Structure<br />

B.C. has 23 REBs that review research involving human subjects, representing 21 academic institutions,<br />

health authorities, <strong>and</strong> community-based organizations (see Appendix 4). In addition, the for-profit<br />

Canadian Western Institutional Review Board (WIRB) located in Vancouver B.C. <strong>and</strong> based in the U.S.,<br />

provides independent REB services to national multi-centre <strong>and</strong> international clinical trials (see Appendix<br />

11). Through an initiative sponsored by the Michael Smith Foundation for Health Research (MSFHR),<br />

the harmonization of REB processes is in progress. 14<br />

Each of B.C.’s six health authorities is responsible for ensuring ethics review of all research protocols to<br />

be carried out at or by an investigator affiliated with a health care facility within its jurisdiction. Geographically<br />

dispersed REBs provide opportunities to bring local perspectives to the review process, incorporating<br />

knowledge of rural communities, ethnic cultures, <strong>and</strong> other issues of local concern. Four of<br />

the six health authorities have established their own REBs, the other two (VCH <strong>and</strong> PHSA) have reached<br />

agreement with UBC to carry out ethics reviews on their behalf except for the PHSA’s adult oncology<br />

protocols, which are reviewed by the BCCA REB.<br />

11<br />

Extracted from The Ethics Review Process in British Columbia: An Environmental Scan. Michael Smith Foundation for Health Research.<br />

October 2007. www.msfhr.org/resources/public/Reports/BC_Scan.pdf. Accessed October 21, 2009.<br />

12<br />

Include: the Nuremberg Code (1948), the Helsinki Declaration (1964), the Belmont Report from The National Commission for the<br />

Protection of Human Subjects of Biomedical <strong>and</strong> Behavioral Research (1979), <strong>and</strong> the International Conference on Harmonization<br />

(ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use guidelines established in 1990 by the European<br />

Union, Japan <strong>and</strong> the U.S.<br />

13<br />

Tri-Council refers to Canada’s three federal research funding agencies: the Canadian Institutes of Health Research (CIHR), the Social<br />

<strong>Sciences</strong> <strong>and</strong> Humanities Research Council (SSHRC), <strong>and</strong> the Natural <strong>Sciences</strong> <strong>and</strong> Engineering Research Council (NSERC).<br />

14<br />

http://www.msfhr.org/special_initiatives/ethics_harmonization. Accessed October 21, 2009.


22<br />

BRITISH COLUMBIA<br />

Much clinical research - particularly cancer-related - is multi-centred <strong>and</strong> collaborative, thus subject to<br />

ethical review by each of the involved institutions. To minimize the requirement for multiple reviews<br />

of research presented to the UBC, Providence, <strong>and</strong> BCCA REBs, these institutions have agreed that the<br />

initial review may be conducted by any of their four REBs <strong>and</strong> that the other three will, in most cases,<br />

honour the outcome of the that review. Further, the REB that reviews <strong>and</strong> approves a protocol is responsible<br />

for subsequent supervision.<br />

The MSFHR-led “B.C. Ethics Harmonization Initiative” 14 is developing a harmonized provincial approach<br />

to ethics approval, including:<br />

• Creating common forms (e.g. application forms, informed consent)<br />

• Developing a shared/ common IT platform <strong>and</strong> tools accessible to researchers <strong>and</strong> institutions at<br />

which human subject research is undertaken in B.C.<br />

• Exploring how ethics review for multi-centre trials can be more efficient, consistent, <strong>and</strong> timely,<br />

possibly with some degree of inter-institutional reciprocity<br />

• Developing common educational <strong>and</strong> training resources to be shared by REBs.<br />

Training Facilities<br />

All B.C.’s CTUs, centres, <strong>and</strong> study sites ensure that their investigators <strong>and</strong> staff are trained in clinical trial<br />

procedures, SOPs, <strong>and</strong> appropriate (i.e., Health Canada, FDA, ICH) GCP regulations <strong>and</strong> guidelines, as<br />

indicated in Appendix 1. Such training is usually in-house or via on-line GCP courses. In addition, there<br />

are at least nine training programs in the Province that specifically focus on clinical trials. These are listed<br />

in Table 4 <strong>and</strong> detailed in Appendix 5.<br />

TABLE 4. <strong>Clinical</strong> <strong>Trials</strong> Training Facilities<br />

Facility (URL)<br />

Description<br />

ASKA Research (http://askaresearch.<br />

trainingcampus.net)<br />

CHEOS <strong>Clinical</strong> Research Education<br />

Series (no specific URL within www.cheos.<br />

ubc.ca)<br />

<strong>Clinical</strong> Research Professional Development<br />

(CRPD) Education Program (www.<br />

cfri-training.ca/training/<strong>Clinical</strong>ResearchCoordinators.asp)<br />

CFRI Monthly Education Forum (www.<br />

cfri-training.ca)<br />

Global Client Partners Consulting Inc.<br />

(www.gcpconsultants.com)<br />

Health Information Science, UVic (http://<br />

hinf.uvic.ca/)<br />

Offers on-line courses <strong>and</strong> guides on ICH/GCP regulations, roles <strong>and</strong> requirements;<br />

GCP-compliant clinical trials for investigators, coordinators, monitors, <strong>and</strong> sponsors;<br />

informed consent; <strong>and</strong> project management.<br />

Offers clinical research education to investigators <strong>and</strong> clinical research coordinators.<br />

Supports professional development of clinical research coordinators <strong>and</strong> research<br />

staff involved in all aspects of clinical research.<br />

Specific to <strong>Clinical</strong> Research Coordinators, an education forum focused on clinical<br />

research.<br />

Offers training in ICH: Good <strong>Clinical</strong> Practice Guidelines; Code of Federal Regulations;<br />

Investigator <strong>and</strong> Coordinator Meetings; St<strong>and</strong>ard Operating Procedures; Essential<br />

Documents; <strong>and</strong> the conduct of investigator-initiated studies.<br />

Offers a range of courses in healthcare management, epidemiology, <strong>and</strong> medical<br />

methodology; with some aspects of courses <strong>and</strong> training relevant to clinical trials<br />

management <strong>and</strong> clinical trials operations.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

23<br />

Facility (URL)<br />

School of Population & Public Health,<br />

UBC (www.spph.ubc.ca)<br />

Society of <strong>Clinical</strong> Research Associates,<br />

Inc., Vancouver Chapter (www.socra.org)<br />

Western Regional Training Centre for<br />

Health Services Research (WRTC) (http://<br />

wrtc-hsr.ca/)<br />

Description<br />

Offers a range of courses in epidemiology <strong>and</strong> healthcare; with several directly<br />

relevant to clinical trials management <strong>and</strong> clinical trials operations. Masters courses<br />

relevant to clinical trials training include:<br />

• The Design <strong>and</strong> Analysis of <strong>Clinical</strong> <strong>Trials</strong><br />

• <strong>Clinical</strong> Epidemiology<br />

• <strong>Clinical</strong> Decision Analysis<br />

• <strong>Clinical</strong> Research Methods for Surgical Procedures.<br />

A non-profit, professional organization dedicated to the continuing education <strong>and</strong><br />

development of clinical research professionals. It offers courses <strong>and</strong> workshops in<br />

subjects such as:<br />

• GCP<br />

• <strong>Trials</strong> management<br />

• SOPs<br />

• Monitoring<br />

• Legal, Ethical <strong>and</strong> Practical Considerations in Protecting Human Research Participants.<br />

A Western Canadian collaborative initiative that supports the postgraduate training<br />

of applied health services researchers across disciplines, sectors, <strong>and</strong> institutions.<br />

Relevant courses include:<br />

• Health Care Research Methods<br />

• Epidemiology of Health Care.<br />

Funding Sources for <strong>Clinical</strong> Research<br />

During the past five years (2005/6 to 2009/10) B.C. conducted over 2,100 clinical trials, excluding<br />

investigator-initiated studies 15 . The level of financial support for these trials was available for 83% of the<br />

studies <strong>and</strong> amounted to more than $100M. Funds were received from industry, governments, patient<br />

groups, <strong>and</strong> other not-for-profit organizations, with sponsor data available for 95% of studies.<br />

Industry sponsored 78% of the trials <strong>and</strong> supplied 62% of the funding (Figures 3 <strong>and</strong> 4). The most<br />

important government sponsor was the Canadian federal government’s Canadian Institutes of Health<br />

Research (Canada’s equivalent of the U.K.’s Medical Research Council or the U.S. National Institutes of<br />

Health [NIH]), which provided over three-quarters of government funding. Although governments provided<br />

33% of funds (Figure 3), such funds covered just 9% of the projects as they included national bulk<br />

funding for the CIHR Canadian HIV <strong>Trials</strong> Network (Figure 4).<br />

15<br />

All clinical trial numerical data in this report are based only on industry-, government-, <strong>and</strong> not-for-profit-sponsored trials. Investigator-initiated<br />

trials have not been included.


24<br />

BRITISH COLUMBIA<br />

FIGURE 3. Source of Funds for <strong>Clinical</strong> <strong>Trials</strong>, 2005/6 - 2009/10<br />

5%<br />

33%<br />

Government<br />

Industry<br />

Not-for-Profit<br />

62%<br />

FIGURE 4. Number of <strong>Clinical</strong> <strong>Trials</strong> According to Sponsor, 2005/6 - 2009/10<br />

N= 269 (13%)<br />

N= 184 (9%)<br />

Government<br />

Industry<br />

Not-for-Profit<br />

N= 1596 (78%)<br />

Industrial Funders<br />

Approximately 260 companies funded clinical trials in B.C. over the past five years. Industrial sponsors<br />

included small start-ups <strong>and</strong> major companies, with investments ranging from less than $1,000 to over<br />

$1M. Median sponsorship was $18,700, with 25% of projects receiving more than $53,000. Sponsors<br />

included all of the world’s top pharmaceutical <strong>and</strong> biotech companies.<br />

Therapeutic Focus of <strong>Clinical</strong> <strong>Trials</strong><br />

<strong>Clinical</strong> trials in B.C. cover all major disease areas. The most important, based on number of studies over<br />

the past five years, are those conducted in cancer, followed by cardiovascular diseases/ cardiology <strong>and</strong><br />

CNS disorders (Figure 5). In terms of dollars, clinical trials in infectious diseases/ infection received the<br />

most funds, in part because of national bulk funding for the CIHR Canadian HIV <strong>Trials</strong> Network. Cancer,<br />

CNS disorders <strong>and</strong> cardiovascular diseases/ cardiology received the next highest levels of funds (Figure<br />

6).


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

25<br />

FIGURE 5. Therapeutic Focus of <strong>Clinical</strong> <strong>Trials</strong> Based on a Number of Studies, 2005/6 - 2009/10<br />

7%<br />

14%<br />

23%<br />

Cancer<br />

CV/Cardiology<br />

CNS<br />

4%<br />

4%<br />

4%<br />

18%<br />

ID/Infection<br />

Gastrointestinal<br />

Genitourinary<br />

Metabolic/Endocrine<br />

11%<br />

15%<br />

Pulmonary<br />

Other<br />

FIGURE 6. Therapeutic Focus of <strong>Clinical</strong> <strong>Trials</strong> Based on Amount of Funding, 2005/06 - 2009/10<br />

6%<br />

6%<br />

9%<br />

23%<br />

Cancer<br />

CV/Cardiology<br />

CNS<br />

3%<br />

3%<br />

9%<br />

ID/Infection<br />

Gastrointestinal<br />

Genitourinary<br />

Metabolic/Endocrine<br />

24%<br />

17%<br />

Pulmonary<br />

Other<br />

“Other” includes anesthesiology, autoimmune, critical care, dental, dermatology, emergency medicine, hematology, musculo-skeletal,<br />

neonatology, obstetrics <strong>and</strong> gynecology, ophthalmology, surgery, <strong>and</strong> transplant.<br />

The distribution in terms of disease specialty <strong>and</strong> funding of the more than 200 pediatric trials included<br />

in this report is somewhat different to the overall pattern, as can be seen in Figure 7. <strong>Trials</strong> on diseases<br />

<strong>and</strong> disorders of the CNS, particularly epilepsy, Fetal Alcohol Spectrum Disorders, <strong>and</strong> Attention Deficit<br />

Hyperactivity Disorder, are the most common, followed by infectious diseases/ infection (mainly vaccine<br />

trials) 16 . The most common pulmonary trials targeted cystic fibrosis, respiratory syncytial virus, <strong>and</strong><br />

asthma.<br />

16<br />

Note that pediatric cancer trials do not come with individual trial funding <strong>and</strong> funding related to disease underestimates the<br />

amount of activity in this area. Using infrastructure funds from the international Children’s Oncology Group (COG), virtually every<br />

child is entered into cancer clinical trials that are seamlessly integrated into their health care.


26<br />

BRITISH COLUMBIA<br />

FIGURE 7. Therapeutic Focus of Pediatric <strong>Clinical</strong> <strong>Trials</strong> Based on Amount of Funding,<br />

2005/06 - 2009/10<br />

10% 6%<br />

Cancer<br />

12%<br />

33%<br />

CNS<br />

8%<br />

3%<br />

3%<br />

ID/Infection<br />

Genitourinary<br />

Hematology<br />

Obs&Gyne<br />

Pulmonary<br />

Other<br />

25%<br />

Types of <strong>Clinical</strong> <strong>Trials</strong><br />

The majority of single trials over the past five years have been dedicated to drug therapies, with diagnostics<br />

trials a distant second in terms of funding (Figure 8). Drug therapies are even more dominant in<br />

terms of number of studies, accounting for 4/5th of all trials. The second most important area according<br />

to study numbers was device treatments (Figure 9).<br />

FIGURE 8. Type of Product Testing in <strong>Clinical</strong> <strong>Trials</strong> Based on Amount of Funding,<br />

2005/06 - 2009/10<br />

10%<br />

5%<br />

13%<br />

62%<br />

10%<br />

Diagnostics<br />

Treatment-Devices<br />

Treatment-Drugs<br />

Treatment-Other<br />

Vaccines<br />

“Treatment Other” includes stem cells, surgery, vitamins, infant formula, <strong>and</strong> exercise.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

27<br />

FIGURE 9. Type of Product Tested in <strong>Clinical</strong> <strong>Trials</strong> Based on Number of Studies,<br />

2005/06 - 2009/10<br />

6%<br />

2%<br />

5%<br />

7%<br />

Diagnostics<br />

80%<br />

Treatment-Devices<br />

Treatment-Drugs<br />

Treatment-Other<br />

Vaccines<br />

<strong>Clinical</strong> trials have also included major components in health economics, health outcomes other than<br />

just a response to experimental therapy, <strong>and</strong> epidemiology. The number of such studies included in the<br />

more than 2,100 trials covered in this report is shown in Figure 10. These studies received $9M in funding<br />

over the past five years.<br />

FIGURE 10. <strong>Clinical</strong> <strong>Trials</strong> with Major Emphasis on Epidemiology, Health Economics,<br />

<strong>and</strong> Health Outcomes<br />

Health Economics 17<br />

Epidemiology 92<br />

Health Outcomes<br />

33<br />

0 20 40 60 80 100<br />

Number of Studies


28<br />

BRITISH COLUMBIA<br />

<strong>Clinical</strong> Investigators<br />

Over 560 investigators in B.C. have received funding to conduct clinical trials over the past five years.<br />

Many of these individuals are world-renowned, with 16 occupying endowed Chairs. All investigators<br />

included in the clinical trials analysis are listed in Appendix 6 in both alphabetical order <strong>and</strong> according<br />

to specialty. The main disease areas in which they work are shown in Figure 11, with some researchers<br />

specializing in more than one area. The distribution of investigator expertise broadly reflects the number<br />

of clinical trials conducted over the past five years, as shown in Figure 5.<br />

As well as specializing in disease areas, some investigators also participate in trials that involve epidemiology,<br />

health economics, health outcomes, <strong>and</strong> pediatrics. The number of such individuals can be seen<br />

in Figure 12. The large number of pediatric trialists reflects the fact that Canada ranks second only to the<br />

U.S. in the number of active, registered clinical trials being conducted in children 17 .<br />

FIGURE 11. Number of <strong>Clinical</strong> <strong>Trials</strong> Investigators According to Disease Specialization<br />

Unknown<br />

Emerency Medicine<br />

Dental<br />

Anethisiology<br />

Transplant<br />

Opthamology<br />

Neonatology<br />

Dermatology<br />

Autoimmune<br />

Surgery<br />

Hematology<br />

Musculo-Skeletal<br />

Gastrointestinal<br />

Critical Care<br />

Obstetrics/Gynecology<br />

Metabolic/Endocrine<br />

Pulmonary<br />

Genitourinary<br />

ID/Infection<br />

CNS<br />

CV/Cardiology<br />

Cancer<br />

6<br />

6<br />

5<br />

8<br />

8<br />

8<br />

9<br />

9<br />

9<br />

10<br />

11<br />

16<br />

19<br />

19<br />

23<br />

30<br />

34<br />

36<br />

48<br />

85<br />

99<br />

127<br />

0 30 60 90 120 150<br />

FIGURE 12. Number of <strong>Clinical</strong> <strong>Trials</strong> Researchers in Other Specialties<br />

Health Economics 15<br />

Health Outcomes 45<br />

Epidemiology 48<br />

Pediatrics 33<br />

86<br />

0 20 40 60 80 100<br />

17<br />

WHO. http://www.who.int/ictrp/child/search/en/. Accessed February 28th, 2010.


29<br />

CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

Hepatitis C 2,479 new case reports in 2008 25<br />

TABLE 5. B.C. Population <strong>and</strong> Largest Visible Minority Groups<br />

Total Population 2009 18<br />

All ages 0-14 years 15-64 years 65+ years<br />

4,455,200 685,500 3,113,400 656,300<br />

Populations 2006 19<br />

Total population 4,074,385<br />

Total visible minority population 1,008,855 (24.8%)<br />

Chinese<br />

407,225 (10% of total population, 40% of visible minority population)<br />

South Asian<br />

262,290 (6.4% of total population, 26% of visible minority population)<br />

First Nations (Aboriginals) 20<br />

196,075 (4.4% of total population)<br />

TABLE 6. Patient Populations for Common Diseases <strong>and</strong> Addictions in B.C.<br />

Disease Area Population Information 21<br />

CNS Conditions<br />

Alcohol addiction 344,000 prevalence 22<br />

Alzheimer’s Disease <strong>and</strong> related disorders<br />

Over 1,200 registered patients with UBC Clinic for Alzheimer’s<br />

Disease <strong>and</strong> Related Disorders 23<br />

Depression <strong>and</strong> anxiety 300,000 patients per year 24<br />

Multiple sclerosis (MS) Over 4,500 registered with UBC MS clinic 23<br />

Parkinson’s disease (PD) <strong>and</strong> Parkinson-like disorders (PLD) 1,100 with typical PD, 400 patients with PLD, 500 – 1,000 dystonia<br />

patients registered with UBC Movement Disorders Clinic 23<br />

Smokers 700,000 prevalence 22<br />

Infectious Diseases<br />

Patient Populations<br />

As B.C. has a single-payer government healthcare program there are no financial barriers to patient<br />

care. Thus, the demographics of potential study patients mirror those of disease occurrence within the<br />

general, ethnically diverse, rapidly growing population of approximately 4.4 million people. Table 5 summarizes<br />

the recent population information for the Province <strong>and</strong> includes the largest minority groups.<br />

Table 6 provides population figures for some of the Province’s most frequently occurring diseases <strong>and</strong><br />

addictions. More details on all populations, including those for many other diseases, can be found in<br />

Appendix 7.<br />

18<br />

Statistics Canada. http://www40.statcan.gc.ca/l01/cst01/demo31a-eng.htm. Accessed December 6, 2009.<br />

19<br />

Statistics Canada. http://www40.statcan.gc.ca/l01/cst01/demo52c-eng.htm. Accessed December 6, 2009.<br />

20<br />

Statistics Canada. www40.statcan.gc.ca/l01/cst01/demo40c-eng.htm. Accessed March 9, 2010. These are people who reported an Aboriginal<br />

identity. They are not included in the 1,008,855 visible minority population.<br />

21<br />

The type of population information varies for different diseases, based on data source.<br />

22<br />

Stepping Forward. Improving Addiction Care in British Columbia. B.C. Medical Association, 2009. http://www.bcma.org/files/Addiction_Stepping_Forward.pdf.<br />

p. 5. Accessed October 22, 2009.<br />

23<br />

Neurosciences <strong>Asset</strong> <strong>Map</strong> British Columbia. www.investbc.com/assetmaps.htm. Accessed October 15, 2009.<br />

24<br />

Stepping Out of the Shadows. Collaborating to Improve Services for Patients with Depression. https://www.bcma.org/files/Depression_paper_<br />

aug13.pdf. p. 12. Accessed October 22, 2009.<br />

25<br />

http://www.bccdc.ca/NR/rdonlyres/59BFCFBB-933D-4337-9305-E3E5FF30D272/0/EPI_Report_CDAnnual2008_20090806.pdf. Accessed November<br />

4, 2009.


30<br />

BRITISH COLUMBIA<br />

TABLE 6. Patient Populations for Common Diseases <strong>and</strong> Addictions in B.C. (cont’d)<br />

Disease Area Population Information 21<br />

HIV ~10,400 prevalence 26<br />

Other Conditions<br />

Arthritis 555,000 prevalence (2008) 27<br />

Asthma 280,600 prevalence (2008) 27<br />

Cancer (all types) 21,190 new cases/year 28 ; 72,300 prevalence (survivors over 10<br />

years) 29<br />

Diabetes 1<br />

87,000 prevalence (2008) 27<br />

Disease Area Population Information 21<br />

Hypertension<br />

55<br />

4,900 prevalence (2008) 27<br />

Obesity 18% of men, 20% of women (prevalence: 2004) 30<br />

Children<br />

Total children treated/ year at B.C. Children’s Hospital > 72,000 31<br />

Other Public <strong>Clinical</strong> <strong>Trials</strong> Support <strong>Infrastructure</strong><br />

B.C. contains a great deal of additional public infrastructure to support clinical trials. This is summarized<br />

below <strong>and</strong> detailed in Appendices 8 – 10.<br />

Biorepositories<br />

Because of its public health system <strong>and</strong> Province-wide tertiary care clinics, B.C. has an exceptional stateof-the-art<br />

collection of appropriately consented tissues, blood, DNA, other molecular data, images, <strong>and</strong><br />

protected clinical information. Tissues are available from patients with cancer, cardiovascular or pulmonary<br />

disease, <strong>and</strong> from those who have undergone organ transplantation or have donated organs. A<br />

brief description of the Province’s six biorepositories can be found in Table 7.<br />

TABLE 7. Biorepositories in B.C<br />

Biorepository Contact Comments<br />

Cancer<br />

Hematology Cell Bank of B.C. (www.<br />

leukemiabmtprogram.org/general_information/research/hematology_cell_bank.<br />

html)<br />

Anna Koochin<br />

T: 604-875-4111 x 67409<br />

akoochin@bccancer.bc.ca<br />

An initiative of the Leukemia/ BMT<br />

Program of B.C., this is a collection of more<br />

than 3,000 samples of blood, bone marrow<br />

material, peripheral blood stem cells, <strong>and</strong><br />

leukapheresis products, as well as related<br />

clinical data from persons with hematologic<br />

malignancies or disorders <strong>and</strong> from<br />

healthy donors for use in research.<br />

26<br />

B.C. Centre for Excellence in HIV/AIDS. http://www.cfenet.ubc.ca/content.phpid=18. Accessed November 22, 2009.<br />

27<br />

Statistics Canada. http://www40.statcan.gc.ca/l01/pro01/pro110-eng.htm. Accessed October 22, 2009.<br />

28<br />

B.C. Cancer Registry Statistics 2007 prepared by Population Oncology March 2009. Includes B.C. residents at diagnosis with any invasive cancer,<br />

excluding non-melanoma skin cancers (BCC, SCC - site C44: histology 8050-8084, 8090-8110). www.bccancer.bc.ca/NR/rdonlyres/27D69A84-8911-<br />

4B97-9073-96F5CEC13961/34420/NumberofCancerDiagnosis1.pdf. Accessed September 29, 2009.<br />

29<br />

Canadian Cancer Statistics, 2009. Canadian Cancer Society. B.C. prevalence is assumed to be approx. 10% of total Canadian prevalence.<br />

30<br />

Statistics Canada. www.statcan.gc.ca/pub/82-620-m/2005001/c-g/adults-adutles/4053576-eng.htm. Accessed March 9, 2010.<br />

31<br />

www.bcchildrens.ca/AboutUs/BCCH/Facts.htm. Accessed November 6, 2009.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

31<br />

Biorepository Contact Comments<br />

Tissue Bank at the Vancouver Prostate<br />

Centre (www.prostatecentre.com<br />

<strong>and</strong> www.pctriadd.com)<br />

Tumour Tissue Repository (TTR), BCCA<br />

(Deeley Research Centre, Victoria) (www.<br />

bccrc.ca/ttr/index.html)<br />

Transplantation<br />

Biomarkers in Transplantation<br />

Biorepository<br />

Other<br />

iCAPTURE BioBank (http://www.<br />

icapture.ubc.ca/home.shtml)<br />

Eye Bank of B.C.; Eye Donation <strong>and</strong><br />

Cornea Transplant Program (http://<br />

www2.vpl.vancouver.bc.ca/DBs/Redbook/orgPgs/3/3123.html)<br />

Antonio Hurtado-Coll<br />

T: 604-875-4111 x 61746.<br />

ahurtado@prostatecentre.com<br />

Peter Watson<br />

T: 250-519-5700 or 1-800-670-3322<br />

TTR@bccancer.bc.ca<br />

Janet McManus<br />

T: 604-806-8328<br />

JMcManus@mrl.ubc.ca<br />

Mike Allard<br />

T: 604-806-9292<br />

actinghead@pathology.ubc.ca<br />

Mark Elliot<br />

T: 604-806-8346 x 62709<br />

mark.elliott@hli.ubc.ca<br />

VGH<br />

T: 604-875-4567; 1-800-667-2060<br />

City wide REB approved biorepository for<br />

genitourinary tissues (prostate, urothelial,<br />

renal, <strong>and</strong> testes cancer) as well as serum<br />

<strong>and</strong> plasma bank.<br />

On behalf of the Province, the BCCA<br />

houses the TTR to support translational<br />

cancer research locally, nationally, <strong>and</strong><br />

internationally. The collection includes<br />

tissues, blood, <strong>and</strong> clinical information<br />

from patient donors <strong>and</strong> a range of tumor<br />

types, accrued under carefully crafted<br />

<strong>and</strong> st<strong>and</strong>ardized consent, collection <strong>and</strong><br />

operational protocols. A core component<br />

of the Canadian National Tumour Bank<br />

Network, the TTR has so far accrued over<br />

1,500 cases.<br />

Biomarkers of injury/ failure in kidney, liver<br />

<strong>and</strong> heart/lung.<br />

An amalgamation of the Cardiovascular<br />

<strong>and</strong> Pulmonary Registries, the locus for<br />

the registration, triage, <strong>and</strong> photography<br />

of all submitted specimens, including<br />

organs, tissues, cells, proteins or genes,<br />

computer images, or clinical information<br />

from humans, animals, cells, <strong>and</strong> cell-free<br />

systems.<br />

The Eye Care Centre at VGH is the provincial<br />

referral centre for the Eye Donation <strong>and</strong><br />

Cornea Transplant Program; it coordinates<br />

the collection, evaluation, <strong>and</strong> distribution<br />

of donor eyes.<br />

Patient Registries<br />

A number of important national <strong>and</strong> Provincial patient registries are housed in B.C., with a breakdown<br />

according to disease area shown in Figure 13. Details can be found in Appendix 8.


32<br />

BRITISH COLUMBIA<br />

FIGURE 13. Provincial <strong>and</strong> National Patient Registries Involving B.C. Investigators<br />

CV/Cardiology<br />

CNS<br />

Pulmonary<br />

Cancer<br />

Infectious Disease<br />

Other<br />

1<br />

2<br />

3<br />

3<br />

4<br />

5<br />

0 1 2 3 4 5<br />

Number<br />

“Other” includes dialysis, transplant, public health, trauma, childhood vasculitis<br />

Healthcare Research Centres<br />

B.C. has at least 60 healthcare research centres that conduct research to aid disease/ health management.<br />

The number of centres focused on each disease or population type are illustrated in Figure 14<br />

while details can be found in Appendix 9. Twenty-four centres are disease-based, while 14 focus on<br />

specific populations (e.g., children, youth, women, the elderly, aboriginals).<br />

FIGURE 14. Breakdown of Healthcare Research Centres According to Focus<br />

Broad-Based 3<br />

Neurosciences<br />

Cancer<br />

Infectious Diseases<br />

3<br />

Cardiovascular<br />

2<br />

Pulmonary<br />

2<br />

Autoimmune Diseases<br />

3<br />

Other Disease-Based<br />

3<br />

Child <strong>and</strong> Youth Health<br />

Women’s Health<br />

Ageing <strong>and</strong> Gerontology<br />

Rural <strong>and</strong> Aboriginal Health<br />

2<br />

Other Health Research<br />

Health Policy, Epidemiology, Health Economics<br />

Environmental Health<br />

2<br />

4<br />

4<br />

4<br />

5<br />

6<br />

9<br />

10<br />

0 2 4 6 8 10


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

33<br />

Technology <strong>and</strong> Informatics Platforms<br />

The Province has a number of cutting-edge technology platforms that offer important informatics, genomics,<br />

pharmacogenomics, proteomics, microarray, <strong>and</strong> other services to those interested in conducting<br />

research intensive (high content) clinical trials (Table 8). Details can be found in Appendix 9 (“Other<br />

Health Research Centres”, Sections 4 <strong>and</strong> 13).<br />

TABLE 8. Technology <strong>and</strong> Informatics Platforms to Support Research Intensive <strong>Clinical</strong> <strong>Trials</strong><br />

Facility (URL)<br />

Services<br />

Centre for Molecular Medicine <strong>and</strong> Therapeutics (CMMT) Multi-platform genotyping, DNA purification, <strong>and</strong> sequencing.<br />

(www.cmmt.ubc.ca)<br />

Centre for Translational <strong>and</strong> Applied Genomics (CTAG) Genomics <strong>and</strong> molecular pathology.<br />

(PHSA/BCCA) (www.phsa.ca/AgenciesAndServices/Services/<br />

PHSA-Labs/About-PHSA-Labs/CTAG.htm)<br />

Genome Research Lab, B.C. Centre for Disease Control Pathogen identification & characterization.<br />

(www.bccdc.ca)<br />

Michael Smith Genome <strong>Sciences</strong> Centre, B.C. Cancer<br />

Agency (PHSA/BCCA) (www.bcgsc.ca)<br />

UVic - Genome B.C. Proteomics Centre (www.proteincentre.<br />

com)<br />

UVic School of Health Information Science (http://hinf.uvic.<br />

ca/)<br />

The Vancouver Prostate Centre - Genome B.C. Microarray<br />

Facility (Vancouver General Hospital/VCH) (www.microarray.<br />

prostatecentre.com) <strong>and</strong> Translational Research Initiative for<br />

Accelerated Discovery <strong>and</strong> Development (PC-TRIADD) Centre of<br />

Excellence for Commercialization <strong>and</strong> Research (CECR) (www.<br />

pctriadd.com)<br />

Sequencing, bioinformatics, mapping, microarray, proteomics,<br />

expression cloning, <strong>and</strong> drug discovery.<br />

Biomarker discovery <strong>and</strong> validation, MALDI imaging, quantitative<br />

proteomics, structural proteomics, peptide synthesis,<br />

protein characterization, protein identification, bioinformatics,<br />

metabolomics.<br />

Consultative service on health informatics, as well as academic<br />

programs.<br />

Microarray facility: Multi-platform facility offering design,<br />

execution <strong>and</strong> interpretation of microarray experiments.<br />

CECR: supports high content clinical trials for GU cancer; only<br />

site in B.C. with Veridex Circulating Tumor Cell technology.<br />

Health Economics <strong>and</strong> Outcomes<br />

As well as individual scientists working in the areas of health economics <strong>and</strong> outcomes, some of whom<br />

are listed in Appendix 6, B.C. has a number of centres <strong>and</strong> programs dedicated to this discipline (Table<br />

9; details in Appendix 9, section 14 unless otherwise stated). These focus on health technology assessment<br />

<strong>and</strong>/or health outcomes research, as well as other areas of health economics.


34<br />

BRITISH COLUMBIA<br />

TABLE 9. Health Economics <strong>and</strong> Health Outcomes Facilities<br />

Name of Facility (URL) Description Contact<br />

Arthritis Research Centre of Canada,<br />

VGH (www.arthritisresearch.ca)<br />

Centre for <strong>Clinical</strong> Epidemiology &<br />

Evaluation (C2E2), VCHRI<br />

(www.c2e2.vchri.ca/)<br />

CFRI <strong>Clinical</strong> Research Support Unit<br />

(www.cfri.ca/research_support/clinical_research_support/default.asp)<br />

CIHR Canadian HIV <strong>Trials</strong> Network<br />

(www.hivnet.ubc.ca)<br />

Centre for Health Evaluation <strong>and</strong><br />

Outcome <strong>Sciences</strong> (CHEOS) (www.<br />

cheos.ubc.ca)<br />

Collaboration for Outcomes Research<br />

<strong>and</strong> Evaluation (CORE), UBC<br />

(www.core.ubc.ca/index.php)<br />

Division of Mathematical Modeling,<br />

UBC/ B.C. Centre for Disease Control<br />

(www.mathmodeling.cdc.ubc.ca/index.<br />

htm)<br />

Patient-oriented research centre, with a<br />

wide range of disciplines including epidemiology,<br />

biostatistics, health psychology,<br />

health economics <strong>and</strong> education.<br />

Focused on evidence-based health care.<br />

Also supports clinical trials investigators<br />

by offering expertise in study design, data<br />

collection <strong>and</strong> management, statistical<br />

analysis, systematic reviews, health<br />

economics.<br />

Offers expertise in epidemiology, statistics<br />

<strong>and</strong> economics. See Appendix 2.<br />

Pharmacoeconomics is a key activity<br />

within this Network, with the Pharmacoeconomics<br />

Program Director (Aslam<br />

Anis) also holding the position of national<br />

co-director of the Network.<br />

Conducts pharmacoeconomic analyses.<br />

Evaluates, interprets <strong>and</strong> disseminates<br />

health outcome information. See Appendix<br />

2<br />

A multidisciplinary group of researchers<br />

with expertise in clinical pharmacy,<br />

pharmacoepidemiology, health economics,<br />

health services research, program<br />

evaluation, <strong>and</strong> health promotion<br />

research. Works in clinical <strong>and</strong> economic<br />

research, <strong>and</strong> pharmaceutical outcomes<br />

assessment. Includes the Community<br />

Pharmacist Research Network (CPRN),<br />

which enables the collection of real-time,<br />

patient-specific data under conditions of<br />

routine clinical care.<br />

Provides mathematical modeling expertise<br />

to public health policy makers in B.C.;<br />

builds infectious disease transmission<br />

models to assist policy design in Canada.<br />

Projects include modeling HPV & influenza<br />

immunization strategies, treatments<br />

for HIV, hepatitis C <strong>and</strong> syphilis.<br />

Kellner, Shauneen. Executive Director.<br />

T: 604-879-7511.<br />

T: 604-875-4043.<br />

C2E2@vch.ca<br />

Junker, Anne, Director, <strong>Clinical</strong> & Population<br />

Health Studies, CFRI.<br />

T: 604-875-3591.<br />

ajunker@cw.bc.ca<br />

Pankovich, Jim. Chief Scientific Officer.<br />

T: 604-806-8340.<br />

jpankovich@mail.hivnet.ubc.ca<br />

Orr, John. Director of Operations.<br />

T: 604-806-2294.<br />

johnorr@mail.cheos.ubc.ca<br />

Marra, Carlo, Director.<br />

T: 604-827-3398.<br />

Carlo.marra@ubc.ca<br />

Westl<strong>and</strong>, Kristin.<br />

T: 604-822-9460. westl<strong>and</strong>@exchange.<br />

ubc.ca<br />

English, Krista. Program Manager.<br />

T: 604.707.2476.<br />

krista.english@bccdc.ca


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

35<br />

Name of Facility (URL) Description Contact<br />

Pharmaceutical Outcomes <strong>and</strong> Policy<br />

Innovations, B.C. Children’s Hospital<br />

(POPi) (www.popi.ubc.ca)<br />

University of Victoria Pharmaceutical<br />

Outcomes <strong>and</strong> Policy Innovation (no<br />

URL)<br />

Pediatric research unit that fosters<br />

pharmaceutical policy innovation through<br />

proactive policy research, training <strong>and</strong><br />

knowledge translation concerning the effectiveness,<br />

safety, <strong>and</strong> cost management<br />

of prescription drugs. Its three general<br />

components are: Drug Safety, Drug Effectiveness,<br />

Drug Policy.<br />

Research unit that studies drug effectiveness,<br />

safety <strong>and</strong> costs to provide decision<br />

makers with cost effective drug coverage<br />

strategies that produce the best health<br />

outcomes.<br />

Carleton, Bruce, Director.<br />

T: 604-875-3609.<br />

bcarleton@popi.ubc.ca<br />

Warburton, Rebecca. Assistant Professor.<br />

T: 250-721-8066.<br />

rnwarbur@uvic.ca<br />

Epidemiology <strong>and</strong> Surveillance Facilities<br />

B.C. is home to numerous epidemiologists who work in public/ population/ community/ environmental<br />

health. This <strong>Asset</strong> <strong>Map</strong> lists some of the researchers that combine epidemiology with new treatment<br />

options <strong>and</strong>/or interventions (lifestyle modification) in Appendix 6. In addition, a number of the Province’s<br />

health research centres have epidemiology or surveillance divisions. Thirteen of these are listed in<br />

Table 10; details can be found in Appendix 9 unless otherwise stated.<br />

TABLE 10. Epidemiology <strong>and</strong> Surveillance Facilities<br />

Facility (URL) Description Contact<br />

Arthritis Research Centre of Canada,<br />

VGH<br />

Described above in Table 9.<br />

B.C. Centre for Disease Control,<br />

Epidemiology Division <strong>and</strong> Immunization<br />

Programs<br />

(http://www.bccdc.ca/util/about/div/<br />

epidemioligy/default.htm)<br />

Centre for Aboriginal Health Research<br />

(CAHR) (www.cahr.uvic.ca)<br />

• Epidemiology Division - Provincial reporting<br />

centre for cases of communicable<br />

disease - monitors <strong>and</strong> evaluates cases<br />

<strong>and</strong> outbreaks, develops prevention <strong>and</strong><br />

control policies <strong>and</strong> programs, <strong>and</strong> supports<br />

the implementation of immunization<br />

programs<br />

• Adverse events surveillance system for<br />

monitoring the public administration<br />

of vaccines (part of its Immunization<br />

Programs).<br />

Research projects in diverse areas of<br />

Aboriginal health including: chronic<br />

disease, disability, First Nations health,<br />

knowledge translation, epidemiology,<br />

global indigenous health, participatory<br />

<strong>and</strong> collaborative community-based<br />

research, <strong>and</strong> health disparities.<br />

Epidemiology Division.<br />

T: 604-707-2510.<br />

Surveillance: Naus, Monika.<br />

T: 604-707-2400.<br />

Monika.naus@bccdc.ca<br />

Lalonde, Chris. Associate Director.<br />

T: 250-721-7535.<br />

lalonde@uvic.ca


36<br />

BRITISH COLUMBIA<br />

TABLE 10. Epidemiology <strong>and</strong> Surveillance Facilities (cont’d)<br />

Facility (URL) Description Contact<br />

Centre for <strong>Clinical</strong> Epidemiology &<br />

Evaluation (C2E2), VCHRI<br />

(www.c2e2.vchri.ca/)<br />

Described above in Table 9.<br />

Centre for Health Evaluation <strong>and</strong><br />

Outcome <strong>Sciences</strong> (CHEOS) (www.<br />

cheos.ubc.ca)<br />

CFRI <strong>Clinical</strong> Research Support Unit<br />

(www.cfri.ca/research_support/clinical_research_support/default.asp)<br />

Immunity & Infection Research<br />

Centre (IIRC), VCHRI (www.iirc.ca/Immunity_<strong>and</strong>_Infection_Research_Centre.<br />

htm)<br />

Integrated Public Health Information<br />

System (iPHIS)<br />

(www.phac-aspc.gc.ca/php-psp/ciphseng.php#wiphis)<br />

Pharmacoepidemiology Hub, B.C.<br />

Mental Health <strong>and</strong> Addictions Research<br />

Institute (BCMHARI) (no URL)<br />

Pharmaceutical Outcomes <strong>and</strong> Policy<br />

Innovations, B.C. Children’s Hospital<br />

(POPi) (www.popi.ubc.ca)<br />

School of Environmental Health<br />

(SOEH) UBC (www.soeh.ubc.ca)<br />

Vaccine Evaluation Centre, BCCH<br />

(www.bcchildrens.ca/Research/Vaccine-<br />

EvaluationCentre) (www.cps.ca/English/<br />

surveillance/impact/impact.htm)<br />

Women’s Health Research Institute<br />

(www.whri.org)<br />

Works in areas of epidemiology <strong>and</strong><br />

population health. See also Tables 3 <strong>and</strong><br />

9.<br />

Offers expertise in epidemiology, statistics<br />

<strong>and</strong> economics. See Appendix 2.<br />

Collaborative team of basic scientists,<br />

clinicians, <strong>and</strong> health professionals whose<br />

expertise includes epidemiology, health<br />

care delivery, <strong>and</strong> policy development.<br />

Automated, integrated, client health record<br />

<strong>and</strong> reporting system that supports<br />

public health provider interventions,<br />

tracking, follow-up, case management,<br />

<strong>and</strong> reporting. Includes surveillance components.<br />

More details in Appendix 9.<br />

Resource for researchers interested in<br />

using B.C.’s prescription database, PharmaNet,<br />

to study patterns of utilization of<br />

pharmacological agents in the treatment<br />

of mental illness <strong>and</strong> addiction.<br />

Described above in Table 9.<br />

SOEH research includes:<br />

• Determinants of exposure<br />

• Epidemiology <strong>and</strong> risk regulation<br />

• Knowledge translation<br />

A node of the Canadian Immunization<br />

Monitoring Program, Active [IMPACT] – a<br />

pediatric hospital-based national active<br />

surveillance network for adverse events<br />

following immunization, vaccine failures<br />

<strong>and</strong> selected infectious diseases in children.<br />

Also conducts epidemiological studies.<br />

Conducts epidemiology studies on<br />

the health <strong>and</strong> health care of girls <strong>and</strong><br />

women.<br />

Orr, John. Director of Operations.<br />

Tel: 604-806-2294.<br />

johnorr@mail.cheos.ubc.ca<br />

Junker, Anne, Director, <strong>Clinical</strong> & Population<br />

Health Studies, CFRI.<br />

T: 604-875-3591. ajunker@cw.bc.ca<br />

Helm, Jeffrey. Research Co-ordinator.<br />

T: 604-875-4111 x 68576.<br />

jhelm@interchange.ubc.ca<br />

S<strong>and</strong>rin, Dilma. iPHIS Program Manager,<br />

BCCDC.<br />

T: 604-707-2501.<br />

Hood, Jane .<br />

Tel: 604-707-6393.<br />

Hurrell, Christie. Executive Director, Centre<br />

for Health <strong>and</strong> Environment Research<br />

T: 604-827-5622.<br />

Bettinger, Julie.<br />

T: 604-875-2422.<br />

jbettinger@cw.bc.ca.<br />

Heath, Katherine. Manager, Research<br />

Development.<br />

T: 604-875-2424 x 4877.<br />

kheath@cw.bc.ca


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

37<br />

Biomarker Translation <strong>and</strong> Development<br />

B.C. has a large cohort of researchers who are identifying biomarkers of disease such as cardiovascular<br />

events, cancer, CNS <strong>and</strong> pulmonary diseases, infection, <strong>and</strong> transplant rejection, <strong>and</strong> translating these<br />

to clinical use. The key institutions involved in biomarker translation <strong>and</strong> development are listed in Table<br />

11. Information on each of these centres can be found in Appendix 9 (sections 3, 5, 7, <strong>and</strong> 13). Of the<br />

more than 2,100 trials included in this report, 27 (funded with over $1M) involved the translation of<br />

biomarkers.<br />

TABLE 11. Centres Involved in the Translation <strong>and</strong> Development of Biomarkers<br />

Centre (URL)<br />

Biomarker Translation <strong>and</strong> Development<br />

B.C. Cancer Research Centre (www.<br />

bccrc.ca)<br />

Centre for Molecular Medicine <strong>and</strong><br />

Therapeutics (www.cmmt.ubc.ca)<br />

Centre for Translational <strong>and</strong> Applied<br />

Genomics (CTAG) (www.phsa.ca/AgenciesAndServices/Services/PHSA-Labs/<br />

About-PHSA-Labs/CTAG.htm)<br />

James Hogg iCAPTURE Centre (Heart<br />

Lung Institute) (www.iCapture.ubc.ca)<br />

Prevention of Organ Failure Centre of<br />

Excellence (PROOF) (www.proof.hli.ubc.ca)<br />

Pharmaceutical Outcomes <strong>and</strong> Policy<br />

Innovations, B.C. Children’s Hospital<br />

(POPi) (www.popi.ubc.ca)<br />

The Vancouver Prostate Centre PC-<br />

TRIADD (www.pctriadd.com)<br />

Diagnostic, prognostic, <strong>and</strong> predictive tests for cancer using biomarkers. Research<br />

depts. involved in such development include the Terry Fox Laboratory <strong>and</strong> Michael<br />

Smith Genome <strong>Sciences</strong> Centre.<br />

Genetic markers that are predictive of severe ADRs for use in diagnostic screening<br />

programs; genetic markers of Huntington’s Disease.<br />

Diagnostics <strong>and</strong> prognostics for cancer, infectious diseases, <strong>and</strong> inherited syndromes.<br />

Licensed out unique single nucleotide polymorphisms that can predict whether a<br />

patient with sepsis will respond to certain treatments; these are being used in the<br />

development of a molecular diagnostic test.<br />

Blood biomarkers that can identify whether a transplanted organ is being rejected.<br />

Involved in the identification <strong>and</strong> translation of biomarkers predictive for drug<br />

adverse reactions.<br />

Development of microarrays <strong>and</strong> next generation sequencing technologies for use as<br />

cancer diagnostics <strong>and</strong> prognostics.<br />

Networks<br />

Provincial networks have been established to leverage expertise within individual B.C. institutions. These<br />

have produced broad-based capabilities that are a lot more than the sum of the parts. The 13 networks<br />

listed in Table 12 support clinical studies.<br />

TABLE 12. Provincial Networks That Support <strong>Clinical</strong> <strong>Trials</strong><br />

Network (URL)<br />

Description<br />

Disease-Based<br />

B.C. Mental Health <strong>and</strong> Addictions<br />

Research Network (www.mhanet.ca)<br />

B.C. Pediatric Oncology Network (www.<br />

bccancer.bc.ca/HPI/CancerManagement-<br />

Guidelines/Pediatric/default.htm)<br />

Builds research capacity <strong>and</strong> generates research that informs policy <strong>and</strong> practice in<br />

the field of mental health.<br />

Enhances the community care of children <strong>and</strong> families by bringing multidisciplinary<br />

teams together to diagnose, manage, <strong>and</strong> follow-up pediatric patients with malignancies<br />

<strong>and</strong> blood disorders.


38<br />

BRITISH COLUMBIA<br />

TABLE 12. Provincial Networks That Support <strong>Clinical</strong> <strong>Trials</strong> (cont’d)<br />

Network (URL)<br />

CardiABC (no URL; Director: Hamburger,<br />

Jaap VGH)<br />

Rick Hansen Spinal Cord Injury Network<br />

(www.rickhansen.com/sections/aboutsci<strong>and</strong>links/docs/YearEndSummary.pdf)<br />

Other<br />

B.C. BioLibrary (www.bcbiolibrary.ca)<br />

B.C. <strong>Clinical</strong> Genomics Network (www.<br />

bccgn.ca)<br />

B.C. <strong>Preclinical</strong> Research Consortium<br />

(www.bcprc.ca)<br />

B.C. Proteomics Network (www.bcpn.ca)<br />

Centre for Healthy Ageing (CHAP) (www.<br />

centreforhealthyaging.ca)<br />

Community Pharmacist Research<br />

Network, CORE, UBC<br />

www.core.ubc.ca/research.php<br />

Description<br />

Vancouver-wide international cardiology research program.<br />

Brings together people with spinal cord injury (SCI), researchers, <strong>and</strong> service providers<br />

to accelerate improvements to the quality of life of people with SCI.<br />

This MSFHR-funded technology/methodology platform complements existing B.C.<br />

biobanks by improving access to human biospecimens for research <strong>and</strong> creating<br />

a framework that promotes appropriate st<strong>and</strong>ards of quality, security, ethics <strong>and</strong><br />

privacy. By improving access to high quality, st<strong>and</strong>ardized biospecimens, it enables<br />

research studies, <strong>and</strong> clinical trials, <strong>and</strong> increases capacity for translational research.<br />

This MSFHR-funded technology/methodology platform assists B.C. clinicians <strong>and</strong><br />

clinical investigators to identify <strong>and</strong> exploit genetic factors involved in the development<br />

of, protection against, <strong>and</strong> treatment of genetic diseases. Provides access to<br />

state-of-the-art genomic technologies <strong>and</strong> services in project co-ordination, methodology,<br />

study design, statistical analysis, consent, ethics, <strong>and</strong> data management.<br />

Provides access to animal based research tools to investigate models of human disease<br />

<strong>and</strong> to assess safe <strong>and</strong> effective treatment solutions designed to alter the course<br />

of disease development <strong>and</strong> progression.<br />

This MSFHR-funded technology/methodology platform connects B.C.’s proteomics<br />

scientists <strong>and</strong> informatics experts; improves access to proteomics instruments/<br />

technology; <strong>and</strong> promotes <strong>and</strong> provides training to increase the underst<strong>and</strong>ing <strong>and</strong><br />

use of proteomics by researchers.<br />

Develops <strong>and</strong> fosters collaborative working relationships between hospitals, universities,<br />

community service providers <strong>and</strong> groups representing elders who share an<br />

interest <strong>and</strong> expertise in the health care needs of older adults in B.C. (see Appendix 9,<br />

Section 11).<br />

Consists of pharmacists in urban <strong>and</strong> rural communities throughout B.C. Enables<br />

collection of patient-specific data under conditions of routine clinical care that can be<br />

used in r<strong>and</strong>omized clinical trials <strong>and</strong> prospective <strong>and</strong> longitudinal studies.<br />

Network Environments for Aboriginal<br />

Research B.C. (www.nearbc.ca)<br />

Population Data B.C. (www.popdata.<br />

bc.ca)<br />

Women’s Health Research Network<br />

(www.whrn.ca)<br />

Increases capacity <strong>and</strong> funding in Aboriginal health research in B.C. by bringing<br />

together multidisciplinary teams from across the Province. Partnership between UVic<br />

<strong>and</strong> University of Northern B.C.<br />

This MSFHR-funded technology/methodology platform holds <strong>and</strong> develops linkages<br />

among population-wide individual-level data from the B.C. Ministry of Health,<br />

WorkSafe B.C., <strong>and</strong> other data stewards in B.C.; supports research access to the data,<br />

providing a hub for cross-sectoral, longitudinal, population-wide research; provides<br />

training in data use.<br />

Links innovative groupings of gender <strong>and</strong> women’s health researchers <strong>and</strong> research<br />

collaborations drawn from academic, health service, policy <strong>and</strong> community settings.<br />

Co-led by investigators at UVic, SFU, UBC.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

39<br />

Many of B.C.’s clinical trials’ investigators are also pivotal players in numerous pan-Canadian <strong>and</strong> international<br />

research networks, with 38 examples illustrated in Table 13 <strong>and</strong> details contained in Appendix<br />

10. Unless otherwise indicated, information on the listed investigators can be found in Appendix 6. A<br />

number of the registries described in Appendix 8 also double as clinical networks. In addition, B.C.’s physicians<br />

actively participate in clinical trials associated with numerous other networks, 32 of which are<br />

listed in Appendix 10. All these networks give B.C.’s investigators unsurpassed links to external experts<br />

<strong>and</strong> resources.<br />

TABLE 13. Examples of National <strong>and</strong> International Networks In Which B.C.’s <strong>Clinical</strong> Investigators<br />

Play a Pivotal Role<br />

Network<br />

B.C. Investigator’s Role<br />

CNS<br />

National<br />

Canadian Network of Multiple Sclerosis VCHRI’s Dessa Sadovnick is on the Executive Committee.<br />

Clinics (http://cnmsc.org/Canadian-Network-Of-Multiple-Sclerosis-Clinics.aspx)<br />

Canadian Northwest FASD Partnership Under the leadership of CFRI in Vancouver.<br />

(www.cnfasdpartnership.ca)<br />

Canadian Stroke Consortium (www. Chaired by UBC’s Phil Teal.<br />

strokeconsortium.ca)<br />

Canadian Stroke Network (www.canadianstrokenetwork.ca)<br />

Brian MacVicar, UBC, is one of the Theme Leaders (does not work in clinical trials).<br />

NeuroDevNet (www.neurodevnet.ca) Led by Dan Goldowitz of CMMT <strong>and</strong> CFRI (does not work in clinical trials).<br />

PrioNet Canada (www.prionetcanada.ca) Based at UBC in Vancouver <strong>and</strong> directed by UBC’s Neil Cashman (does not work in<br />

clinical trials).<br />

International<br />

Pacific Rim Workgroup Against Epilepsy CFRI’s Peter Wong is a founding member.<br />

(no URL)<br />

Cancer/ Hematology<br />

National<br />

Network<br />

B.C. Investigator’s Role<br />

The C17 Council (www.c17.ca)<br />

CFRI’s Paul Rogers is one of the Council members <strong>and</strong> Co-Chair of the Cancer Care for<br />

Adolescents <strong>and</strong> Young Adults Committee.<br />

Canadian Blood & Marrow Transplant CFRI’s Kirk Schultz is a prominent member.<br />

Group (www.cbmtg.org)<br />

Canadian Urologic Oncology Group<br />

(CUOG) (www.cuog.org)<br />

Children’s Oncology Group (COG) (www.<br />

childrensoncologygroup.org)<br />

Headquartered in Vancouver. VGH’s Martin Gleave is past Chair of <strong>and</strong> a continuing<br />

member of the Executive Committee; BCCA’s Tom Pickles <strong>and</strong> Kim Chi are members of<br />

the Executive Committee.<br />

CFRI’s Paul Rogers is a prominent member.


40<br />

BRITISH COLUMBIA<br />

TABLE 13. Examples of National <strong>and</strong> International Networks In Which B.C.’s <strong>Clinical</strong> Investigators<br />

Play a Pivotal Role (cont’d)<br />

Network<br />

National Cancer Institute of Canada<br />

<strong>Clinical</strong> <strong>Trials</strong> Group (NCIC CTG) (www.<br />

cancer.ca/research/)<br />

International<br />

Australian-Canadian Prostate Cancer<br />

Research Alliance (www.aus-canprostatealliance.org)<br />

National Cancer Institute (U.S.)-Canada<br />

<strong>Clinical</strong> <strong>Trials</strong> Group (www.cancer.gov/<br />

cancertopics/factsheet/NCI/clinical-trialscooperative-group)<br />

Pediatric Bone <strong>and</strong> Marrow Transplant<br />

Consortium (PBMTC) (www.pbmtc.org)<br />

Infectious Diseases<br />

National<br />

CAIRE - Canadian Association for Immunization<br />

Research (www.caire.ca)<br />

CIHR Canadian HIV <strong>Trials</strong> Network<br />

(www.hivnet.ubc.ca)<br />

Pan-Provincial Vaccine Enterprise (PRE-<br />

VENT) http://www.prevent-cecr.ca/<br />

Pediatric Investigators Collaborative<br />

Network on Infections in Canada (see<br />

www.ncbi.nlm.nih.gov/pmc/articles/<br />

PMC2827737/)<br />

PrioNet Canada (www.prionetcanada.ca)<br />

Public Health Agency of Canada -<br />

Canadian Institutes of Health Research<br />

Influenza Research Network (PCIRN)<br />

(www.pcirn.ca)<br />

International<br />

SARS Accelerated Vaccine Initiative<br />

(SAVI) (www.savi-info.ca)<br />

B.C. Investigator’s Role<br />

Kim Chi is on the Genitourinary (GU) Disease Site Executive Committee; Chair of the<br />

sub-site Advanced Prostate group; <strong>and</strong> Executive Committee Member <strong>and</strong> Chair-elect<br />

of the Investigational New Drug Site; Stephen Chia is on the <strong>Clinical</strong> <strong>Trials</strong> Committee<br />

<strong>and</strong> Breast Site Executive Committee; Hagan Kennecke is on the GI Executive<br />

Committee; Christopher Lee is on the Lung Site Executive Committee; Martin Gleave<br />

is past Chair of <strong>and</strong> continues to be a member of the GU <strong>Clinical</strong> <strong>Trials</strong> Group Executive<br />

Committee.<br />

The Vancouver Prostate Centre is the Canadian Hub of this alliance <strong>and</strong> a founding<br />

member.<br />

BCCA’s Kim Chi is on the Prostate Cancer Task Force Committee; BCCA’s Hagan Kennecke<br />

is on the Neuroendocrine Task Force Committee.<br />

CFRI’s Kirk Schultz is past Chair.<br />

BCCH’s David Scheifele is Chair.<br />

Based at St Paul’s Hospital, Vancouver B.C. National Director is Martin Schechter,<br />

PHCRI.<br />

A Canadian western regional office is located at BCCDC, Vancouver.<br />

BCCH’s David Scheifele is a leading member.<br />

Based at UBC, Vancouver B.C. See above.<br />

The Rapid Vaccine <strong>Trials</strong> are led by David Scheifele of BCCH, <strong>and</strong> BCCDC.<br />

Based at BCCDC <strong>and</strong> UBC, this is a B.C.-led international consortium.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

41<br />

Network<br />

B.C. Investigator’s Role<br />

Maternal <strong>and</strong> Child Health (not Disease Specific)<br />

National<br />

Canadian Mother Infant Child Youth Directed by Anne Junker, CFRI, Vancouver B.C.<br />

Research Network (MICYRN) (www.<br />

micyrn.ca)<br />

Canadian Neonatal Followup Network CFRI’s Anne Synnes is the Director <strong>and</strong> chairs the Steering Committee <strong>and</strong> Database<br />

(CFUN) (www.cnfun.ca)<br />

Working Group.<br />

Canadian Neonatal Network (www. Founded by ex-CFRI investigator, Shoo Lee.<br />

canadianneonatalnetwork.org)<br />

Canadian Perinatal Network (www. Led by Rob Liston <strong>and</strong> Laura Magee, CFRI, Vancouver.<br />

cpn-rpc.org)<br />

Canadian Pediatric Anesthesiology CFRI investigator Gillian Lauder is a co-founder. Others, including Martin Ansermino,<br />

Research Network (www.micyrn.ca/ are members.<br />

documents/PINC Meeting Report November<br />

5 2009.pdf)<br />

Canadian Pediatric Surgery Network Founded by CFRI’s Eric Skarsgard <strong>and</strong> coordinated by B.C. Children’s Hospital.<br />

(CAPSnet) (www.capsnetwork.org)<br />

International<br />

International Alliance for Better Medicines<br />

for Children (no URL)<br />

clinical trials).<br />

Leadership provided by Stuart MacLeod <strong>and</strong> Bob Peterson at CFRI (do not conduct<br />

North American Fetal Therapy Network CFRI’s Alain Gagnon is a founding member.<br />

(www.naftnet.org)<br />

Other<br />

National<br />

Canadian Thoracic Society (www.lung. VCHRI’s Mark Fitzgerald is on Executive Committee; VCHRI’s Jeremy Road is Chair of<br />

ca/cts-sct/about-propos_e.php)<br />

Research Committee.<br />

Canadian Urological Association (CUA) The Vancouver Prostate Centre’s Martin Gleave is Chair of the CUA Scholarship Foundation<br />

Research Council.<br />

(www.cua.org)<br />

International<br />

American Bronchology Association VCHRI’s Stephen Lam is past Director.<br />

(www.aabronchology.org)<br />

Canadian Alliance of Pediatric Rheumatology<br />

Investigators (CAPRI) (www. a PI on the REACCH OUT project.<br />

CFRI’s David Cabral is a member of the interim steering committee; <strong>and</strong> Lori Tucker is<br />

icaare.ca/index.phpoption=com_content&<br />

task=view&id=44&Itemid=80)<br />

Canadian Pharmacogenomics Network A joint initiative of POPi <strong>and</strong> CMMT (CFRI), Vancouver B.C.<br />

for Drug Safety<br />

Childhood Arthritis & Rheumatism Research<br />

Alliance (CARRA) (www.carragroup.<br />

CFRI’s David Cabral <strong>and</strong> Lori Tucker are co-founders.<br />

info; www.arthritis.org/carra.php)


42<br />

BRITISH COLUMBIA<br />

TABLE 13. Examples of National <strong>and</strong> International Networks In Which B.C.’s <strong>Clinical</strong> Investigators<br />

Play a Pivotal Role (cont’d)<br />

Network<br />

Integrative Analysis of Longitudinal<br />

Studies of Aging (IALSA) Research Network<br />

(http://lifelab.tss.oregonstate.edu/)<br />

International Photodynamic Association<br />

(IPA) (http://sites.pcmd.ac.uk/ipa/<br />

index.php)<br />

National Core for Neuroethics (www.<br />

neuroethics.ubc.ca)<br />

B.C. Investigator’s Role<br />

Co-directed by Scott Hofer, Victoria B.C.<br />

VCHRI’s Stephen Lam is a past President.<br />

Based at UBC in Vancouver B.C.<br />

Independent Corporations Offering <strong>Clinical</strong> <strong>Trials</strong> Services<br />

B.C. is home to at least 25 independent organizations that offer clinical trials services, as listed in Table<br />

14 <strong>and</strong> Appendix 11. These are generally for-profit (the exception is the Victoria Heart Institute Foundation).<br />

The focus of these companies is shown in Figure 15, with 64% involved in setting up <strong>and</strong> managing<br />

clinical trials. Of the eight investigator-operated clinical trials companies, five are disease-specific<br />

(one each dealing with cancer, urology, endocrinology, gastrointestinal, <strong>and</strong> cardiology). A number of<br />

the analytical services companies also offer preclinical services (see below).<br />

FIGURE 15. Focus on Independent <strong>Clinical</strong> <strong>Trials</strong> Organizations<br />

N= 4 (16%)<br />

N= 8 (32%)<br />

PI Managed <strong>Clinical</strong> <strong>Trials</strong> Company<br />

N= 5 (20%)<br />

Other <strong>Clinical</strong> <strong>Trials</strong> Management Companies<br />

Analytical Services<br />

Other<br />

N= 8 (32%)<br />

Other = two health outcomes consultancies; one REB; one medical software company


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

43<br />

TABLE 14. Independent <strong>Clinical</strong> <strong>Trials</strong> Organizations<br />

Company/ URL<br />

ASKA Research (www.askaresearch.com) *<br />

B.C. Biomedical Laboratories Ltd.<br />

(www.bcbio.com) *<br />

B.C. Community Oncology Trialists (COT)<br />

(no URL)*<br />

BRI Biopharmaceutical Research Inc.<br />

(www.bripharm.com) *<br />

Can-Med <strong>Clinical</strong> Research Inc (www.<br />

can-med.ca) *<br />

CanTest Ltd. (www.cantest.com) *<br />

(Acquired by Maxxam Analytics October<br />

23rd, 2009)<br />

Canadian Western Institutional Review<br />

Board (WIRB) (www.wirb.com)<br />

Discovery *<br />

Fraser <strong>Clinical</strong> Trial Inc. (no URL) *<br />

Global Client Partners Consulting Inc.<br />

(www.gcpconsultants.com) *<br />

Interior <strong>Clinical</strong> Research Consultants<br />

Ltd. (no URL) *<br />

LAIR Centre (www.laircentre.com) *<br />

<strong>Life</strong>Labs Medical Laboratory Services<br />

(www.lifelabs.com/<strong>Life</strong>Labs_BC/)<br />

MDIT Innovations Inc. (www.mditinnovations.com/)*<br />

Medical Arts Health Research Group<br />

(www.healthresearch.ca) *<br />

Nanaimo Research Institute (www.<br />

nri-nanaimo.ca) *<br />

Okanagan <strong>Clinical</strong> <strong>Trials</strong> (www.oktrials.<br />

ca) *<br />

Oxford Outcomes (www.oxfordoutcomes.<br />

com)<br />

Services<br />

All aspects of CT management <strong>and</strong> monitoring services through Phases I to IV in all<br />

areas of pharma. No data management or processing.<br />

Medical diagnostic services for the B.C. health care system, as well as providing<br />

collection, management, <strong>and</strong> testing services for clinical trials, scientific research <strong>and</strong><br />

other initiatives.<br />

Independent clinical trials company formed by oncologists that work outside the<br />

BCCA in community oncology sites.<br />

Provides specialized <strong>and</strong> integrated drug c<strong>and</strong>idate <strong>and</strong> preclinical drug development<br />

contract research services for worldwide regulatory submissions, as well as clinical<br />

Phase I/II bioanalytical assays.<br />

Conducts clinical trials in urology (including prostate <strong>and</strong> bladder cancer) on Vancouver<br />

Isl<strong>and</strong>. Also provides support services to other clinical investigators <strong>and</strong> sites.<br />

Offers integrated analytical <strong>and</strong> specialized testing to industries <strong>and</strong> regulators assessing<br />

environmental quality, pharmaceutical/ biotechnology efficacy, food quality,<br />

<strong>and</strong> drug residues. Provides pharmaceutical testing including GLP <strong>and</strong> non-GLP<br />

analytical testing for all stages of the drug development process.<br />

For-profit organization based in the U.S., with representatives located in Vancouver, B.C.<br />

Provides independent IRB services, often to industry-sponsored national multi-centre<br />

<strong>and</strong> international clinical trials for biomedical, behavioural, <strong>and</strong> social sciences studies.<br />

n/a<br />

Independent clinical trials company, conducting studies in cardiology, GI, <strong>and</strong> oncology.<br />

Provides services for investigator-initiated <strong>and</strong> biopharmaceutical clinical trials, such<br />

as protocol development, trial <strong>and</strong> data management, monitoring, regulatory issues,<br />

study reports. Also offers medical writing <strong>and</strong> training.<br />

Sets-up <strong>and</strong> manages mainly Phases II <strong>and</strong> III clinical trials in all areas of nephrology,<br />

cardiology, respirology, orthopedics, general surgery, <strong>and</strong> critical care.<br />

Located in Vancouver, conducts Phases I, II, <strong>and</strong> III clinical trials in patients with liver<br />

<strong>and</strong> inflammatory bowel disease.<br />

Provides clinical laboratory testing services across Canada with 80 service centres<br />

across B.C. Offers specialized services in B.C. for clinical trials.<br />

Provides clinical management systems (software) for the medical industry.<br />

A clinical research organization that conducts Phases II, III, <strong>and</strong> IV clinical trials in the<br />

Okanagan Valley. Covers chronic diseases in most therapeutic areas.<br />

Participates in Phase III <strong>and</strong> Phase IV national <strong>and</strong> global clinical research in cardiology/<br />

cardiovascular diseases, orthopedics, diabetes, <strong>and</strong> palliative care.<br />

Conducts clinical trials on an out-patient basis for the pharmaceutical industry. Phase<br />

II - IV trials in a variety of therapeutic areas.<br />

International health outcomes consultancy with offices in Vancouver. Specializes in<br />

health outcomes, health economics, epidemiology.


44<br />

BRITISH COLUMBIA<br />

TABLE 14. Independent <strong>Clinical</strong> <strong>Trials</strong> Organizations (cont’d)<br />

Company/ URL<br />

Pacific Nuclear Medicine Inc. (no URL) *<br />

PerCuro <strong>Clinical</strong> Research Ltd. (no URL) *<br />

PRA International (www.prainternational.com)<br />

ProHealth <strong>Clinical</strong> Research (www.<br />

prohealthcr.ca) *<br />

Syreon Corp. (www.syreon.com) *<br />

SLC Laboratories (www.slclabs.com) *<br />

Victoria Heart Institute Foundation<br />

(www.vhif.org) *<br />

*Home-grown companies.<br />

Services<br />

Located at Lions Gate Hospital; specializes in undertaking clinical trials for new biopharmaceuticals<br />

which are labeled with radioactive tracers for both radiodiagnosis<br />

<strong>and</strong> radiotherapy.<br />

Conducts Phases II-IV out patient clinical trials in the areas of rheumatology, dermatology,<br />

gastroenterology, <strong>and</strong> infectious diseases (in particular Hepatitis C).<br />

Large multi-national multi-capability CRO providing International services through<br />

all phases of clinical development with facilities in Victoria B.C.<br />

Specializes in Phases I – IV clinical trials in men’s health, postmenopausal women’s<br />

health, metabolic bone diseases (osteoporosis) <strong>and</strong> endocrine disease (including<br />

diabetes).<br />

<strong>Clinical</strong> trial research corporation providing expertise in molecular medicine,<br />

biostatistics, clinical therapeutics, economics, health outcomes measurement, <strong>and</strong><br />

economics. Conducts national <strong>and</strong> international Phase I to IV clinical <strong>and</strong> pharmacovigilance<br />

studies.<br />

Offers customized analytical <strong>and</strong> bioanalytical services to the pharmaceutical, natural<br />

health product, <strong>and</strong> functional food industries. It also provides experience in bioanalytical<br />

support for clinical studies in Japan in association with Japanese affiliate Epoch<br />

Medical International Inc.<br />

Non-profit, charitable organization dedicated to conducting <strong>and</strong> supporting cardiovascular<br />

research on Vancouver Isl<strong>and</strong>.<br />

Successes<br />

B.C.’s clinical trials successes are too numerous to mention. However, an indication of the world-class<br />

expertise available in the Province can be seen above in the number of trials, investigators, CTUs/<br />

centres/ study sites, <strong>and</strong> sponsors, as well as the central location of many national <strong>and</strong> international<br />

networks <strong>and</strong> other facilities. B.C. investigators are the founders or co-founders of the Canadian Pharmacogenomics<br />

Network for Drug Safety, the CIHR Canadian HIV <strong>Trials</strong> Network, the Pacific Rim Workgroup<br />

Against Epilepsy, PrioNet Canada, the SARS Accelerated Vaccine Initiative (SAVI), the Canadian Urologic<br />

Oncology Group, <strong>and</strong> various NCIC <strong>Clinical</strong> <strong>Trials</strong> Groups. They have also been first author on numerous<br />

peer-reviewed papers, including the most prestigious journals such as the New Engl<strong>and</strong> Journal of<br />

Medicine 32 ,. Furthermore, they hold large peer-reviewed grants from such international organizations<br />

as the U.S. National Cancer Institute <strong>and</strong> NIH, as well as Canadian funders including the National Cancer<br />

Institute of Canada (NCIC) (now the Canadian Cancer Society Research Institute), CIHR, <strong>and</strong> the National<br />

Science <strong>and</strong> Engineering Research Council (NSERC).<br />

The Province also has its commercial successes. As indicated in Table 14, at least 21 home-grown companies<br />

offering clinical trials services operate in B.C. A 22nd company, PRA International, has facilities in<br />

B.C. because it purchased a B.C. company, CroMedica.<br />

32<br />

A few examples: (1) Abu-Laban RB, Christenson JM, Innes GD, et al. Tissue plasminogen activator in cardiac arrest with pulseless electrical activity.<br />

N Engl J Med. 2002 May 16;346(20):1522-8. (2) Hogg JC, Chu F, Utokaparch S, et al. The nature of small-airway obstruction in chronic obstructive<br />

pulmonary disease. N Engl J Med. 2004 Jun 24;350(26):2645-53. (3) Russell JA, Walley KR, Singer J, et al; VASST Investigators. Vasopressin versus norepinephrine<br />

infusion in patients with septic shock. N Engl J Med. 2008 Feb 28;358(9):877-87. (4) Gleave ME, Mostafa E, Fradet Y, et al. Canadian Urologic<br />

Oncology Group. Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma. N Engl J Med. 1998;338:1305-1306.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

45<br />

ORGANIZATIONS OFFERING PRECLINICAL SERVICES<br />

There are at least six major organizations offering various preclinical services in B.C., as illustrated in<br />

Table 15. Companies offer analytical services (N=2), medical device development (N=2) <strong>and</strong> preclinical<br />

drug development (N=2). Details can be found in Appendices 11 <strong>and</strong> 12.<br />

TABLE 15. Organizations Offering Services for <strong>Preclinical</strong> Studies<br />

Organizations<br />

Services<br />

BCCA Investigational Drug Program<br />

(www.bccrc.ca/at/focus_investigationaldrugprogram.html)<br />

BRI Biopharmaceutical Research Inc.<br />

(www.bripharm.com)<br />

CanTest Ltd. (www.cantest.com)(Acquired<br />

by Maxxam Analytics October 23rd, 2009)<br />

Centre for Drug Research <strong>and</strong> Development<br />

(www.cdrd.ca)<br />

Product <strong>and</strong> Process Applied Research<br />

Team (PART) Technology Centre (www.bcit.<br />

ca/appliedresearch/part/)<br />

Star Fish Medical (www.starfishmedical.<br />

com)<br />

Provides facilities for the pharmaceutical formulation, manufacturing <strong>and</strong> pre-clinical<br />

testing of new parenteral drugs for Phase I <strong>and</strong> II clinical trials in a GLP Lab.<br />

See Table 14.<br />

See Table 14.<br />

Provides drug development expertise <strong>and</strong> infrastructure to enable researchers<br />

throughout B.C. to develop promising drug c<strong>and</strong>idates. Provides expertise in five divisions<br />

that mirror the drug-development process: Target Validation, Drug Screening,<br />

Medicinal Chemistry, Drug Delivery, Drug Evaluation.<br />

A specialist medical device consultancy that provides applied research services<br />

to validate <strong>and</strong> commercialize medical, industrial, <strong>and</strong> consumer products <strong>and</strong><br />

processes; performs contract services to researchers; <strong>and</strong> develops proof of concept<br />

prototypes.<br />

Designs, develops <strong>and</strong> manufactures medical devices. Specializes in electro-mechanical<br />

devices, diagnostic, <strong>and</strong> imaging equipment.


46<br />

BRITISH COLUMBIA<br />

COMPARATIVE POSITIONING OF B.C. WITHIN CANADA<br />

Since no other Canadian Province has conducted an in-depth review of its capabilities <strong>and</strong> infrastructure<br />

for pre-clinical studies <strong>and</strong> clinical trials, it is difficult to determine how B.C. compares. However, an<br />

indication of the Province’s ranking in clinical trials can found by comparing Canadian population statistics<br />

with the number of studies listed in clintrials.gov (a registry of U.S. federal <strong>and</strong> privately supported<br />

clinical trials conducted around the world) (Table 16) 33 . Using this surrogate method, B.C. compares<br />

quite well - it has the third largest population in Canada <strong>and</strong> manages the third highest number of clinical<br />

trials.<br />

TABLE 16. Comparative Positioning of B.C. in its Conduct of <strong>Clinical</strong> <strong>Trials</strong><br />

Region Name<br />

Number of <strong>Clinical</strong><br />

<strong>Trials</strong><br />

Ranking of Province<br />

by Number of<br />

<strong>Trials</strong><br />

Population ‘000<br />

Canada 6701 34 33,327.30<br />

Alberta 1866 4 3,595.90 4<br />

British Columbia 1912 3 4,383.80 3<br />

Manitoba 900 6 1,206.10 5<br />

New Brunswick 397 9 747.1 8<br />

Newfoundl<strong>and</strong> <strong>and</strong> Labrador 497 8 506.4 9<br />

Nova Scotia 1035 5 936.60 7<br />

Ontario 4404 1 12,936.30 1<br />

Prince Edward Isl<strong>and</strong> 113 10 139.5 10<br />

Quebec 2632 2 7,753.50 2<br />

Saskatchewan 707 7 1,013.60 6<br />

Ranking of Province<br />

by Population<br />

33<br />

http://clinicaltrials.gov/ct2/search/map/clickmap.x=139&map.y=107 <strong>and</strong> Statistics Canada: www40.statcan.ca/l01/cst01/demo02a-eng.htm.<br />

Accessed January 27, 2010.<br />

34<br />

More than one Province is generally involved in each study, hence the total figure for Canada is much lower than the sum of Provincial trials.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

47<br />

OPPORTUNITIES FOR COLLABORATION<br />

The aforementioned has highlighted B.C.’s infrastructure in clinical trials <strong>and</strong> supporting preclinical<br />

services. The Province’s physicians <strong>and</strong> companies provide collaborative opportunities for interested<br />

parties, whether they be not-for-profit organizations, governments, or companies. All CTUs, centres, <strong>and</strong><br />

study sites would welcome additional studies.<br />

B.C. has a particular capacity for research intensive (high content) clinical trials, with its expertise in biomarker<br />

translation <strong>and</strong> development <strong>and</strong> numerous Health Research Centres. The latter include worldclass<br />

facilities in informatics, genomics, proteomics, microarrays, pharmacogenomics, epidemiology,<br />

<strong>and</strong> health economics. Comprehensive tissue databases <strong>and</strong> patient registries are aligned with many<br />

Provincial clinical research opportunities <strong>and</strong> access to these is available to potential collaborators.<br />

Finally, the Province’s single-payer government healthcare program <strong>and</strong> associated uniform treatment<br />

policies ensures that there are a significant numbers of potential patients who can be asked to participate<br />

in trials.


48<br />

BRITISH COLUMBIA<br />

ACKNOWLEDGEMENTS<br />

This report could not have been completed without the participation of the numerous people who are<br />

listed in Appendix 13. We would particularly like to thank Genome B.C., which sponsored the study, <strong>and</strong><br />

International BioPharma Solutions Ltd. which conducted the work.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

49<br />

APPENDICES


50<br />

BRITISH COLUMBIA<br />

APPENDIX 1-2<br />

TABLE OF CONTENTS<br />

Appendix 1. Description of B.C.’s <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites<br />

Provincial Health Services Authority 52<br />

B.C. Cancer Agency 52<br />

BCCA Centre for the Southern Interior, <strong>Clinical</strong> <strong>Trials</strong> Unit 52<br />

Edward Miller <strong>Clinical</strong> Research Unit, BCCA - Fraser Valley Centre 54<br />

Medical Oncology <strong>Clinical</strong> <strong>Trials</strong> Unit, BCCA Vancouver Centre 54<br />

Radiation Therapy Research Program, BCCA Vancouver Centre 56<br />

Vancouver Isl<strong>and</strong> Centre Radiation Therapy Research Business Unit (VIC RT RBU) 56<br />

VIC Systemic Therapy <strong>Clinical</strong> <strong>Trials</strong> Unit, BCCA Vancouver Isl<strong>and</strong> Centre 57<br />

B.C. Children’s Hospital 59<br />

Endocrinology <strong>and</strong> Diabetes Unit 59<br />

General Surgery 59<br />

Neonatal Research Program 60<br />

Neurosciences Program 62<br />

Pediatric Anesthesia Department 62<br />

Pediatric Oncology/ BMT/ Hematology 62<br />

Pediatric Rheumatology Program 63<br />

Provincial Medical Genetics Program 63<br />

Vaccine Evaluation Centre 63<br />

Women & Family HIV Centre 64<br />

B.C. Women’s Hospital 65<br />

Obstetric Medicine Program 65<br />

Maternal Fetal Medicine Research Unit 65<br />

Fraser Health Authority 66<br />

Burnaby Hospital Regional Cancer Centre 66<br />

Cardiology <strong>Clinical</strong> <strong>Trials</strong> Inc., Surrey Memorial Hospital 66<br />

Fraser Health Critical Care Group 67<br />

Multiple Sclerosis Clinic 67<br />

Orthopedics Department 68<br />

Ridge Meadows Hospital 68<br />

Interior Health Authority 69<br />

Kidney Clinic 69<br />

Penticton Regional Hospital Research Department 69<br />

Providence Health Care Society 70<br />

St. Paul’s Hospital 70<br />

AIDS Research Program 70<br />

CIHR Canadian HIV <strong>Trials</strong> Network (CTN) 71<br />

Emergency Medicine Research Group 72<br />

Foot <strong>and</strong> Ankle Clinic Orthopedics Research Group 72<br />

Heart Centre 72<br />

Hematology Research Group 73<br />

James Hogg iCAPTURE Centre 73<br />

Pacific Lung Health Centre 74


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

51<br />

Vancouver Coastal Health 75<br />

Vancouver General Hospital 75<br />

Arthritis Research Centre 75<br />

B.C. Centre for Stroke <strong>and</strong> Cerebrovascular Diseases 75<br />

Cardiology Research 75<br />

Centre for Menstrual Cycle <strong>and</strong> Ovulation Research 76<br />

Dermatology <strong>Clinical</strong> <strong>Trials</strong> Unit 77<br />

Downtown Infectious Diseases Clinic 77<br />

Diabetes Research Centre 78<br />

Epilepsy Clinic 78<br />

Hematology Research <strong>and</strong> <strong>Clinical</strong> <strong>Trials</strong> Unit (HRCTU) 78<br />

The Lung Centre 79<br />

Nephrology Research Unit/ Group, VGH <strong>and</strong> St Paul’s Hospital 80<br />

Neurosurgery Division, VGH 82<br />

Psychiatry Administration - VGH 82<br />

The Vancouver Prostate Centre 83<br />

Vancouver Retinal Research Group 83<br />

UBC Hospital 84<br />

Alzheimer Disease & Related Disorders’ Clinic 84<br />

Bladder Care Centre 84<br />

Mood Disorders Centre of Excellence UBC: <strong>Clinical</strong> <strong>Trials</strong> Section 85<br />

Multiple Sclerosis Clinic 86<br />

Pacific Parkinson’s Research Centre 86<br />

University of British Columbia Medical Departments Supporting B.C. Hospitals 87<br />

Anesthesia Department 87<br />

Critical Care Medicine 87<br />

Endocrinology <strong>and</strong> Metabolism 87<br />

Gastroenterology 88<br />

Obstetrics <strong>and</strong> Gynecology Department 88<br />

Appendix 2. Description of B.C.’s <strong>Clinical</strong> <strong>Trials</strong> Support Units<br />

Providence Health Care Society 89<br />

Providence Health Care Research Institute (PHCRI) <strong>and</strong> the Centre for Health<br />

Evaluation <strong>and</strong> Outcome <strong>Sciences</strong> (CHEOS) 89<br />

Provincial Health Services Authority 94<br />

Child <strong>and</strong> Family Research Institute (CFRI) <strong>Clinical</strong> Research Support Unit 94<br />

Laboratory-<strong>Clinical</strong> Studies Unit 100<br />

Fraser Health Authority 101<br />

Fraser Health Research & Evaluation 101<br />

Vancouver Coastal Health 102<br />

Vancouver Coastal Health Research Institute (VCHRI) <strong>Clinical</strong> Research Unit 102<br />

Vancouver Isl<strong>and</strong> Health Authority 103<br />

VIHA Research Department 103


52<br />

BRITISH COLUMBIA<br />

APPENDIX 1.<br />

DESCRIPTION OF B.C.’S CLINICAL TRIALS UNITS, CENTRES,<br />

AND STUDY SITES<br />

PROVINCIAL HEALTH SERVICES AUTHORITY<br />

B.C. Cancer Agency<br />

The British Columbia Cancer Agency (BCCA) (www.bccancer.bc.ca) is responsible for both patient care<br />

<strong>and</strong> research within a single operational structure. It provides a population-based cancer care program,<br />

including prevention, screening <strong>and</strong> early detection, diagnosis <strong>and</strong> treatment services, rehabilitation<br />

support <strong>and</strong> community programs, research, <strong>and</strong> education. Thus, unlike most other jurisdictions which<br />

move patients from primary <strong>and</strong> secondary to tertiary care facilities as their disease progresses, B.C.’s<br />

cancer patients are generally managed by the same tumour specific team from first therapy to final outcome.<br />

A complete record of a patient’s management (e.g., therapy, outcomes, etc.) is housed within a<br />

centralized registry managed by the BCCA. Biological samples from each patient are stored in biorepositiories.<br />

Tumour teams are responsible for therapeutic protocols <strong>and</strong> policy decisions, rapidly translating<br />

experimental medicines <strong>and</strong> novel processes into routine care if the outcomes data support this.<br />

FIGURE A1. Key <strong>Clinical</strong> <strong>Trials</strong> <strong>and</strong> <strong>Preclinical</strong> Studies Facilities at the BCCA<br />

BCCA<br />

<strong>Clinical</strong> <strong>Trials</strong> Unit<br />

Advanced Therapeutics<br />

Investigational Drug Program<br />

Tumour Tissue Repository<br />

Medical Oncology,<br />

Vancouver Centre<br />

Edward Miller,<br />

Fraser Valley<br />

Centre for the<br />

Southern Interior<br />

Radiation Therapy Research<br />

Program, Vancouver Centre<br />

VIC Radiotherapy,<br />

Vancouver Isl<strong>and</strong><br />

VIC Systemic Therapy,<br />

Vancouver Isl<strong>and</strong><br />

The Agency has five clinical locations: Vancouver Centre, Abbotsford, Fraser Valley (in Surrey), Vancouver<br />

Isl<strong>and</strong> (in Victoria), <strong>and</strong> Southern Interior (in Kelowna). It contains a number of units important to the<br />

clinical <strong>and</strong> preclinical infrastructure in B.C., as shown in Figure A1. Details of the six clinical trials units<br />

(CTUs) are given below. Brief information on the Advanced Therapeutics Investigational Drug Program<br />

<strong>and</strong> Tumour Tissue Repository can be found in Appendix 12 <strong>and</strong> Table 7 of the main text.<br />

BCCA Centre for the Southern Interior, <strong>Clinical</strong> <strong>Trials</strong> Unit<br />

The BCCA’s Centre for the Southern Interior is based in Kelowna (www.bccancer.bc.ca/RS/Centreforthe-<br />

SouthernInterior/). It is the centre of cancer research, education, prevention, diagnosis <strong>and</strong> treatment


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

53<br />

in the Southern Interior of B.C. The Centre has 16 Principal Investigators as listed below, <strong>and</strong> 4 Associate<br />

Investigators. It has a matrix structure as shown in Figure A2. The facility has no independent URL.<br />

The Unit conducts Phases I, II, <strong>and</strong> III clinical trials. They accrue approximately 150 patients per year.<br />

The Principal Investigators at the Centre for the Southern Interior are as follows. Their details can be<br />

found in Appendix 6.<br />

• Czerkawski, Barbara • Mohamed, Islam<br />

• Delorme, Mike • Petrik, David<br />

• Ellard, Susan<br />

• Rao, Sanjay<br />

• Fyles, Gillian<br />

• Reed, Melanie<br />

• Halperin, Ross<br />

• Salhus, Terje<br />

• Hoegler, David • Sauciuc, Delia<br />

• Khoo, Kong<br />

• Sutherl<strong>and</strong>, Judy<br />

• Kim, David<br />

• Taylor, Marianne<br />

Unit staffing is as follows:<br />

Study Nurses 1<br />

Data Managers/ Coordinators<br />

Pharmacy Staff Laboratory Staff Administration<br />

3.9 4.6 1 6 1.6<br />

Potential clinical trials at the Centre are reviewed by a <strong>Clinical</strong> <strong>Trials</strong> Committee in the first instance. If approved,<br />

an application for study approval is submitted to the UBC-BCCA Research Ethics Board.<br />

FIGURE A2. Structure of the Centre for the Southern Interior CTU<br />

Director <strong>Clinical</strong><br />

Operations<br />

PPL Pharmacy Regional<br />

Medical Leader PI’s<br />

Administrator<br />

Radiation<br />

Therapists<br />

Pharmacist Nurses Data<br />

Coordinators<br />

Unit Clerk<br />

Laboratory<br />

Technician<br />

Secretary<br />

Pharmacy<br />

Technician<br />

Quality control/ assurance procedures are based on BCCA St<strong>and</strong>ard Operating Procedures compliant<br />

with Good <strong>Clinical</strong> Practice guidelines. All research staff are trained appropriately in GCP.<br />

Contact:<br />

Broughton, S<strong>and</strong>ra. Regional Administrator. Tel: 250-712-3903. sbroughton@bccancer.bc.ca.<br />

1<br />

Study nurses at CTUs/ centres, <strong>and</strong> study sites generally perform the role of a clinical research coordinator (defined as a link between a clinical trial<br />

sponsor, the investigator, <strong>and</strong> the study site), as well as conducting activities such as patient management, h<strong>and</strong>s-on patient care, REB submissions,<br />

regulatory documentation <strong>and</strong> coordination, training of assistants, etc).


54<br />

BRITISH COLUMBIA<br />

Edward Miller <strong>Clinical</strong> Research Unit, BCCA - Fraser Valley Centre<br />

The BCCA - Fraser Valley Centre (www.bccancer.bc.ca/RS/FraserValleyCentre/) is one of five full service<br />

cancer centres of the BCCA, providing oncology consultations, chemotherapy <strong>and</strong> radiotherapy treatments<br />

for people who live in the Fraser Valley. The BCCA - Fraser Valley Centre is an active research clinic.<br />

<strong>Clinical</strong> trials are an extremely important aspect of its clinical care <strong>and</strong> the Edward Miller <strong>Clinical</strong> Research<br />

Unit (CRU) is involved in a growing research program (www.bccancer.bc.ca/RS/FraserValleyCentre/research.htm).<br />

The 10 Principal Investigators at the Edward Miller CRU are as follows. Their details can be found in Appendix<br />

6.<br />

• Agranovich, Alex<strong>and</strong>er • Lee, Christopher<br />

• Al-Tourah, Abdul • Lee, Ursula<br />

• Chan, Theresa<br />

• Leong, Carson<br />

• Johal, Bal<br />

• Martin, Lee Ann<br />

• Kwan, Winkle<br />

• Pansegrau, Gary<br />

The Unit conducts primarily Phase II <strong>and</strong> III clinical trials. It conducts very limited Phase I activity <strong>and</strong> occasionally<br />

undertakes Phase IV trials. It accrues approximately 70 patients per year.<br />

Unit staffing is as follows:<br />

Study Nurses 1<br />

Data Managers/ Pharmacy Staff Laboratory Staff Administration*<br />

Coordinators<br />

2.6 FTE 2 2.6 FTE 0.5 FTE 0.5 FTE 1.4 FTE<br />

* Secretary, clerk.<br />

Potential clinical trials are reviewed at the Fraser Valley Centre by investigators, the CRU, <strong>and</strong> centre<br />

processes affected by a given trial prior to approval.<br />

Quality control procedures are based on extensive BCCA St<strong>and</strong>ard Operating Procedures compliant<br />

with Good <strong>Clinical</strong> Practice (GCP) guidelines. All research staff are trained appropriately in clinical trials<br />

<strong>and</strong> GCP.<br />

Contact:<br />

Lee, Christopher. Medical Director. Tel: 604-930-4017. clee@bccancer.bc.ca.<br />

Medical Oncology <strong>Clinical</strong> <strong>Trials</strong> Unit, BCCA Vancouver Centre<br />

The Medical Oncology CTU at the BCCA’s Vancouver Centre consists of three business units, each specializing<br />

in specific tumor sites (see Figure A3). Each business unit team is led by a dedicated oncologist/<br />

Principal Investigator.<br />

2<br />

Full-time equivalent.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

55<br />

FIGURE A3. Leadership Structure of the BCCA’s Medical Oncology CTU<br />

Susan O’Reilly<br />

Vice President,<br />

Cancer Care<br />

Mr. Kelly Uyeno<br />

CTU Business Manager<br />

Dr. Kim Chi<br />

Director,<br />

<strong>Clinical</strong> <strong>Trials</strong> Unit<br />

Ms. Roe<br />

CTU<br />

Operations Manager<br />

Dr. Stephen Chia<br />

Business Unit 1:<br />

Breast/Head <strong>and</strong> Neck/Sarcoma<br />

T: 604-877-6000 x 2746<br />

schia@bccancer.bc.ca<br />

Dr. Kim Chi<br />

Business Unit 2:<br />

GU/CNS/Lung/Phase I:<br />

T: 604-877-6000 x 2746<br />

kchi@bccancer.bc.ca<br />

Dr. Hagen Kennecke<br />

Business Unit 3:<br />

GI/Gyn/Skin/Lymphoma<br />

T: 604-877-6000 x 2746<br />

hkennecke@bccancer.bc.ca<br />

The total number of investigators in the Unit is 27 (listed below). Their details can be found in Appendix 6.<br />

Cheung, W Kennecke, H O’Reilly, S<br />

Chi, K Klasa, R Savage, K<br />

Chia, S Knowling, M Sehn, L<br />

Connors, J Kollmannsberger, C Shah, A<br />

Gelmon, K Laskin, J Shenkier, T<br />

Gill, S Lim, H Sun, S<br />

Hawley, P Lohrisch, C Swenerton, K<br />

Ho, C Melosky B Thiessen, B<br />

Hoskins, P Murray, N Tinker, A<br />

The Unit conducts all Phases of clinical trials except Phase IV (i.e., Phases 0, I, II, <strong>and</strong> III). They accrue approximately<br />

400 patients <strong>and</strong> open <strong>and</strong> complete approximately 40 trials per year. The facility has no<br />

independent URL.<br />

Unit staffing is as follows:<br />

Study Nurses 1 Data Coordinators Pharmacy Staff Laboratory Staff Administration*<br />

11 14** 3 (part-time) 5.5 (2 in CTU) 3<br />

* 2: Contracts <strong>and</strong> other legal documents, budget negotiation, accounting; 1: human resources, project management.<br />

**Deal with data entry, regulatory issues, <strong>and</strong> REB submissions.<br />

Quality control/ assurance procedures are based on extensive BCCA St<strong>and</strong>ard Operating Procedures compliant<br />

with Good <strong>Clinical</strong> Practice guidelines. All projects are approved by the REB prior to initiation <strong>and</strong> all<br />

research staff are trained appropriately in GCP <strong>and</strong> clinical trials.<br />

Contact:<br />

Chi, Kim. Director. Tel: 604-877-6000 x 2746. kchi@bccancer.bc.ca.


56<br />

BRITISH COLUMBIA<br />

Radiation Therapy Research Program, BCCA Vancouver Centre<br />

The Radiation Therapy Research Program conducts radiation therapy collaborative group clinical trials,<br />

industry sponsored clinical trials, developmental <strong>and</strong> technical research, <strong>and</strong> operations research. It also<br />

undertakes outcomes evaluation, dosimetry studies, <strong>and</strong> other qualitative research. It has no independent<br />

URL.<br />

The Program has a large pool of qualified investigators, some of whom are listed below <strong>and</strong> in Appendix<br />

6.<br />

• Duzenli, Cheryl • Nichol, Alan<br />

• Hay, John<br />

• Parsons, Christina<br />

• Keyes, Mira<br />

• Tyldesley, Scott<br />

• Lim, Peter<br />

• Weir, Lorna<br />

• McKenzie, Michael • Wu, Jonn<br />

• Morris, James<br />

The Unit conducts all Phases of clinical trials (0 – IV) <strong>and</strong> accrues approximately 200 patients per year.<br />

Unit staffing is as follows:<br />

Study Nurses 1<br />

All clinical staff participate<br />

in trials, equating<br />

to ~ 1 FTE at any one<br />

time<br />

Data Managers/ Research Pharmacy/ Lab Staff Administration/ Support<br />

Assistants 3 Staff<br />

2 0 1 part-time Manager<br />

New trials are approved by the RT Research Committee prior to submission to the REB.<br />

Quality control/ assurance procedures are based on extensive BCCA St<strong>and</strong>ard Operating Procedures<br />

compliant with Good <strong>Clinical</strong> Practice (GCP) guidelines. All research staff are trained appropriately in<br />

GCP, clinical trials, <strong>and</strong> these SOPs. There are extensive QA protocols for radiation therapy procedures,<br />

<strong>and</strong> the Radiation Therapy Research Program also ensures QA by using a QUARC model. All projects are<br />

approved by the REB prior to initiation.<br />

Contact:<br />

(1) French, John. Director of <strong>Clinical</strong> Operations. Tel: 604 877 6000 x 2780. JFrench2@bccancer.bc.ca.<br />

(2) Lim, Peter. Acting Professional Practice Leader - Radiation Oncology. Tel: 604-877-6000 x 2650. plim@<br />

bccancer.bc.ca.<br />

Vancouver Isl<strong>and</strong> Centre Radiation Therapy Research Business Unit (VIC RT RBU)<br />

The VIC RT RBU is part of the Vancouver Isl<strong>and</strong> Centre (VIC), one of the BCCA’s five full service cancer<br />

centres. The unit was established in 2006, with the m<strong>and</strong>ate of operating research studies <strong>and</strong> trials for<br />

the Radiation Therapy Program at the VIC. Many of the unit’s trials involve testing of innovative radiation<br />

therapy techniques in a clinical setting <strong>and</strong> include large, multi-centre cooperative trials (NCIC, NSABP,<br />

3<br />

Research Assistants generally support the study coordinators/nurses - assisting with forms, administrative duties, sample h<strong>and</strong>ling, etc.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

57<br />

OCOG, RTOG) to smaller Vancouver Isl<strong>and</strong> Centre-driven trials (e.g., in-house pilot studies) (http://www.<br />

bccancer.bc.ca/RS/VancouverIsl<strong>and</strong>Centre/research/clinicaltrials/rtrbu.htm <strong>and</strong> http://www.bccancer.<br />

bc.ca/RES/Clin<strong>Trials</strong>/Open<strong>Trials</strong>/VIC.htm). It conducts all aspects of clinical trials, from eligibility screening<br />

to data management <strong>and</strong> analysis.<br />

The Unit conducts Phases I, II, III clinical trials. Its accrual rate varies by year, depending on the number<br />

<strong>and</strong> type of trials open, ranging from 82 in 2008-9 to 210 in 2006-7.<br />

The RBU has four Principal Investigators, listed below (with details in Appendix 6), <strong>and</strong> 25-30 co-investigators<br />

<strong>and</strong> associates, including radiation oncologists, medical physicists, radiation therapists <strong>and</strong><br />

nurses.<br />

• Berrang, Tanya • Truong, Pauline<br />

• Pai, Howard<br />

• Wai, Elaine<br />

Unit staffing is as follows:<br />

Study Nurses 1 Research Assistants 3 Data Managers/ Coordinators<br />

Pharmacy Staff Admin./ Support<br />

1 1 0 0.7 FTE* 0.8 FTE<br />

*1 part-time pharmacist <strong>and</strong> 1 part-time pharmacy technician shared with the BCCA VIC Systemic Therapy CTU.<br />

The unit uses the Vancouver Isl<strong>and</strong> Centre <strong>and</strong> Vancouver Isl<strong>and</strong> Health Authority for its pharmacy* <strong>and</strong><br />

laboratory needs.<br />

New trials are reviewed <strong>and</strong> approved by the VIC RTRBU <strong>and</strong> VIC RT leadership, as well as the BCCA/UBC<br />

REB.<br />

Quality control/ assurance procedures are based on extensive BCCA St<strong>and</strong>ard Operating Procedures<br />

compliant with ICH, FDA, <strong>and</strong> Health Canada Good <strong>Clinical</strong> Practice (GCP) guidelines. All research staff<br />

are trained appropriately in GCP <strong>and</strong> these SOPs. For National Cancer Institute of Canada (NCIC) trials,<br />

certification of NCIC GCP is also required for investigators <strong>and</strong> RBU staff. All projects are reviewed <strong>and</strong><br />

approved by the UBC/BCCA REB prior to initiation.<br />

Contact:<br />

Truong, Pauline. Radiation Oncologist. Tel: 250-519-5500. ptruong@bccancer.bc.ca.<br />

Beckham, Wayne. Head, Medical Physics. Tel: 250-519-5500. WBeckham@bccancer.bc.ca.<br />

VIC Systemic Therapy <strong>Clinical</strong> <strong>Trials</strong> Unit, BCCA Vancouver Isl<strong>and</strong> Centre<br />

The BCCA Vancouver Isl<strong>and</strong> Centre (www.bccancer.bc.ca/RS/VancouverIsl<strong>and</strong>Centre/) is one of five full<br />

service cancer centres of the BCCA, providing oncology consultations, chemotherapy <strong>and</strong> radiotherapy<br />

treatments, as well as screening, genetic counseling, <strong>and</strong> supportive care, for people who live on<br />

Vancouver Isl<strong>and</strong>. The VIC Systemic Therapy <strong>Clinical</strong> <strong>Trials</strong> Unit (STCTU) (www.bccancer.bc.ca/RS/VancouverIsl<strong>and</strong>Centre/research/clinicaltrials/stctu/)<br />

is responsible for conducting most of the clinical trials for<br />

the department of Medical Oncology at the Vancouver Isl<strong>and</strong> Centre. These clinical trials are generally<br />

industry sponsored or intergroup studies, mainly involving drug therapy.


58<br />

BRITISH COLUMBIA<br />

The Unit has 15 Principal Investigators, listed below. Their details can be found in Appendix 6.<br />

• Allan, Sharon<br />

• Martins, Heidi<br />

• Anderson, Helen • McMurtrie, Elissa<br />

• Attwell, Andrew • Michels, Jorg<br />

• Bernstein, Vanessa • Souliere, Sheila<br />

• Fitzgerald, Catherine • Weinerman, Brian<br />

• Hart, Jason<br />

• Wilson, Kenneth<br />

• MacLean, Grant • Yee, Adrian<br />

• Macpherson, Nichol<br />

The Unit conducts primarily Phase II <strong>and</strong> III clinical trials. It conducts very limited Phase I activity <strong>and</strong><br />

rarely undertakes Phase IV trials. It accrues approximately 60 – 75 patients per year.<br />

Unit staffing is as follows:<br />

Study Nurses 1 Research Assistants<br />

3<br />

Data Managers/<br />

Coordinators<br />

2.3 FTE 1 FTE 2.2 FTE 0.4 Pharmacist,<br />

0.3 Technician<br />

* Shared with the BCCA VIC Radiation Therapy RBU.<br />

** 0.5 FTE CTU Manager, 1 FTE Clerk, 1 FTE Secretary.<br />

The STCTU’s structure is shown in Figure A4.<br />

FIGURE A4. VIC Systemic Therapy <strong>Clinical</strong> <strong>Trials</strong><br />

Provincial Systemic<br />

Therapy Program<br />

Leader<br />

Pharmacy Staff* Laboratory Staff Admin./ Support<br />

**<br />

Contracted to<br />

hospital<br />

2.5 FTE<br />

Director, <strong>Clinical</strong><br />

Operations Systemic<br />

Therapy VIC<br />

Manager<br />

Medical Director<br />

Principal<br />

Investigators Medical<br />

Oncology<br />

Nurse Coordinators Data Coordiantors Support Staff,<br />

Secretary, Clerk<br />

Research Assistant<br />

Pharmacy<br />

New trials are presented at monthly investigator meetings. All go through a Resource Impact Analysis<br />

that is completed by the investigator, clinical trials data coordinator, nurse coordinator, pharmacy, <strong>and</strong><br />

management.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

59<br />

Quality control/ assurance procedures are based on extensive BCCA St<strong>and</strong>ard Operating Procedures<br />

compliant with ICH, FDA, <strong>and</strong> Health Canada Good <strong>Clinical</strong> Practice (GCP) guidelines. All projects are<br />

approved by the REB prior to initiation <strong>and</strong> all research staff are trained appropriately in GCP <strong>and</strong> these<br />

SOPs. The Unit also participates in monitor visits <strong>and</strong> periodic audits.<br />

Contact:<br />

den Duyf, Johanna. Director, Systemic Therapy <strong>and</strong> ST <strong>Clinical</strong> <strong>Trials</strong> Unit. Tel: 250-519-5591. jdenduyf@<br />

bccancer.bc.ca.<br />

B.C. Children’s Hospital<br />

B.C. Children’s Hospital (BCCH) (www.bcchildrens.ca) is the only pediatric health centre <strong>and</strong> teaching<br />

hospital in B.C., <strong>and</strong> the largest full-service child health centre in Western Canada. As B.C.’s tertiary care<br />

facility, it delivers child <strong>and</strong> youth physical <strong>and</strong> mental health <strong>and</strong> rehabilitation services for the most seriously<br />

ill or injured children from across the province. It provides care for more than 72,000 children <strong>and</strong><br />

adolescents every year, including 900 children with cancer, 140 undergoing open-heart surgery, 1,200<br />

needing intensive care, <strong>and</strong> approximately 2,300 children for the assessment of developmental issues<br />

<strong>and</strong>/or requiring rehabilitation (the latter activities are conducted at BCCH’s Sunny Hill Health Centre for<br />

Children.<br />

Endocrinology <strong>and</strong> Diabetes Unit<br />

The Endocrinology & Diabetes Unit has an active program for both basic-science <strong>and</strong> clinical research,<br />

particularly in diabetes <strong>and</strong> healthy lifestyles (www.bcchildrens.ca/Services/SpecializedPediatrics/EndocrinologyDiabetesUnit/default.htm).<br />

<strong>Clinical</strong> investigators include the following whose details can be found in Appendix 6:<br />

• Amed, Shazhan • Metzger, Daniel<br />

• Chanoine, Jean-Pierre • Panagiotopoulos, Constadina<br />

Contact:<br />

Chanoine, Jean-Pierre. Head, Division of Pediatric Endocrinology. Tel: 604-875-2624. jchanoine@cw.bc.ca.<br />

General Surgery<br />

The General Surgery Division provides surgical treatment for head <strong>and</strong> neck, thoracic, digestive, <strong>and</strong><br />

oncologic diseases for children of all ages. The division plays an active role in the treatment of birth<br />

defects, traumatic injuries, <strong>and</strong> vascular access, including extracorporeal membrane oxygenation (www.<br />

bcchildrens.ca/Services/SurgeryAndSurgSuites/GeneralSurgery/default.htm). <strong>Clinical</strong> research includes<br />

novel fetal therapies, especially those, such as gene replacement, applicable via “minimally invasive”<br />

surgical techniques. The investigators are also interested in outcomes following neonatal surgery. Dr.<br />

Skarsgard is creating a surgical, Canada-wide database that will allow illness-severity stratification of<br />

specific surgical conditions <strong>and</strong> enable “best practice” assessments for a number of neonatal conditions<br />

requiring surgery after birth (see www.cfri.ca/our_research/researchers/search_researchers/researcher_<br />

detail.aspID=123).<br />

Contact:<br />

Skarsgard, Erik. Head, Division of Pediatric General Surgery. Tel: 604-875-3744. eskarsgard@cw.bc.ca.


60<br />

BRITISH COLUMBIA<br />

Neonatal Research Program<br />

Neonatology is an area of health care in which decisions can impact dramatically on the future quality<br />

of life of both patients <strong>and</strong> their families. To support this decision process, research is an integral part of<br />

the daily activities in the Program. A core group of health researchers are involved in individual activities<br />

that combine to create a comprehensive, complementary approach to minimizing the long-term<br />

effects of prematurity. The researchers have demonstrated expertise in: basic science (i.e., inflammation<br />

<strong>and</strong> oxidants), clinical research (i.e., r<strong>and</strong>omized controlled trials, neonatal brain imaging), health<br />

services research (i.e., ACoRN-community outreach) <strong>and</strong> population health (i.e., Neonatal Follow-up).<br />

Specific areas of clinical interest are: ventilation <strong>and</strong> critical care therapy, role of immunity <strong>and</strong> genetics<br />

in neonatal disease, nutrition, stress/pain, brain development <strong>and</strong> injury, <strong>and</strong> long-term neurodevelopment.<br />

The Program offers investigators:<br />

• Protocol, informed consent <strong>and</strong> budget review<br />

• Assistance with grant preparation/ submission<br />

• REB preparation <strong>and</strong> submission - including amendments, renewals <strong>and</strong> requests for acknowledgement<br />

• Set-up of study account <strong>and</strong> tracking financial expenses of study<br />

• Data collection, management <strong>and</strong> analysis<br />

• Liaising with pharmacy, laboratory, health records, neonatal intensive care unit (NICU) nursing or<br />

other groups as necessary to help with study initiation<br />

• Hiring <strong>and</strong> training of research staff<br />

• Review, preparation <strong>and</strong> submission of abstracts/manuscripts<br />

• Review/Development of sub-site clinical trial agreements<br />

• Access to the opportunity to conduct Phase I, II, III, <strong>and</strong> IV clinical trials <strong>and</strong> biomedical research<br />

within the NICU, which admits approximately 700 in-patients per year.<br />

The Program includes 13 Principal Investigators as listed below, <strong>and</strong> five Affiliated Investigators. Their<br />

details can be found in Appendix 6. Its structure is shown in Figure A5. It has no independent URL.<br />

Principal Investigators<br />

• Chessex, Philippe (Head)<br />

• Albersheim, Susan<br />

• Holsti, Liisa<br />

• Lavoie, Pascal<br />

• Lupton, Brian<br />

• Miller, Steven<br />

• Osiovich, Horacio<br />

• Sherlock, Rebecca<br />

• Singh, Avash<br />

• Smyth, John<br />

• Solimano, Alfonso<br />

• Synnes, Anne<br />

• Whitfield, Michael<br />

The following table shows all the research interests of each investigator in neonatology, not just clinical<br />

trials:<br />

Disease Focus Types of Studies Investigators<br />

Effects of nutrition, oxidants, <strong>and</strong> antioxidants Animal studies<br />

Chessex, Philippe<br />

on biological markers <strong>and</strong> clinical outcome R<strong>and</strong>omized clinical trials<br />

Ethics <strong>and</strong> decision-making in a vulnerable Qualitative research Albersheim, Susan<br />

population<br />

Stress/pain <strong>Clinical</strong> research Holsti, Liisa


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

61<br />

Disease Focus Types of Studies Investigators<br />

Role of immunity <strong>and</strong> genetics in neonatal Basic science<br />

Lavoie, Pascal<br />

disease<br />

<strong>Clinical</strong> research<br />

Quality Improvement<br />

Lupton, Brian<br />

Brain development <strong>and</strong> injury<br />

<strong>Clinical</strong> research<br />

Miller, Steven<br />

Advanced MRI technologies<br />

Critical care therapies <strong>Clinical</strong> research Osiovich, Horacio<br />

Neonatal ventilation<br />

Epidemiology<br />

Sherlock, Rebecca<br />

R<strong>and</strong>omized clinical trials<br />

Critical care therapies Pharmaceutical trials Singh, Avash<br />

Critical care therapies <strong>Clinical</strong> research Smyth, John<br />

Ventilation <strong>and</strong> critical care therapies<br />

Education & knowledge translation<br />

Solimano, Alfonso<br />

Long-term neurodevelopmental outcome<br />

Knowledge translation<br />

Long term follow-up<br />

KT methodologies<br />

Synnes, Anne<br />

Long-term neurodevelopmental outcome Long term follow-up Whitfield, Michael<br />

FIGURE A5. Neonatal Research Program<br />

Division Head:<br />

Chessex, Philippe<br />

Principal<br />

Investigators<br />

Research Manager:<br />

Jennifer Claydon<br />

Lead Research<br />

Coordinators<br />

Data Abstractors<br />

Lab Manager<br />

Science Writer<br />

Study Nurses/<br />

Research Assistants<br />

Student/<br />

Lab Assistant<br />

Staffing of the Neonatal Research Program is as follows:<br />

Study Nurses/ Research Assistants<br />

Data Abstractors Pharmacy Staff Laboratory Staff Admin.<br />

Coordinators 1<br />

3<br />

12 1 2 0 4* 2**<br />

* 1 Manager, 1 assistant, 2 co-op students.<br />

** 1 Manager, 1 science writer.


62<br />

BRITISH COLUMBIA<br />

The B.C. Children’s Hospital pharmacy is used for research studies.<br />

Prior to initiation of a trial at the facility, it must be presented at a monthly Research Meeting for approval.<br />

Researchers work together with the Research Manager to develop trial specific procedures that<br />

are in line with the guidelines for conducting research in this vulnerable population that have been set<br />

out by the Program.<br />

To ensure Quality Control <strong>and</strong> Assurance, the facility <strong>and</strong> its investigators follow Tri-Council (CIHR,<br />

NSERC, SSHERC) <strong>and</strong> ICH-GCP guidelines. Furthermore, the Program has extensive st<strong>and</strong>ard guidelines<br />

for all research within the NICU, which focuses specifically on the fact that the research involves<br />

a vulnerable population. All new research staff are trained in Tri-council, ICH-GCP, <strong>and</strong> Neonatal Program<br />

guidelines. Each study maintains a specific procedure manual that conforms with these research<br />

st<strong>and</strong>ards <strong>and</strong> outlines the specific requirements of that study. Finally, annual audits are performed to<br />

ensure study files are appropriate <strong>and</strong> up to date, <strong>and</strong> that research st<strong>and</strong>ards (regarding guidelines,<br />

defined study-specific procedures, SOPs, REB renewal, etc.) are being met.<br />

Contact:<br />

Claydon, Jennifer. Research Program Manager. Tel: 604-875-2000 x 7408. jclaydon@cw.bc.ca.<br />

Neurosciences Program<br />

<strong>Clinical</strong> trials investigators within the Neurosciences Program are focused on drug therapies <strong>and</strong> technology<br />

assessments for neurological conditions such as epilepsy <strong>and</strong> neuromuscular disease (www.<br />

bcchildrens.ca/Services/Neurosciences/ProgramsServices.htm).<br />

Contact:<br />

Farrell, Kevin, <strong>Clinical</strong> Neurologist. Tel: 604-875-2976. kfarrell@cw.bc.ca.<br />

Pediatric Anesthesia Department<br />

The Pediatric Anesthesia Department cares for children of all ages with many different medical conditions<br />

(www.bcchildrens.ca/Services/SurgeryAndSurgSuites/AnesthesiaService/default.htm). It provides<br />

sedation <strong>and</strong> anesthesia for a wide range of surgical <strong>and</strong> diagnostic procedures, as well as pain management.<br />

A major research focus is on the use of new technology, <strong>and</strong> the information derived from<br />

such advances, to reduce patient risk in anesthesia <strong>and</strong> intensive care (see www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=3).<br />

Contact:<br />

Ansermino, Mark. Director of Research. Tel: 604-875-2711. anserminos@yahoo.ca.<br />

Pediatric Oncology/ BMT/ Hematology<br />

BCCH is a major centre for pediatric oncology <strong>and</strong> hematology studies. Headed by Dr. Paul Rogers,<br />

the Pediatric Oncology/BMT /Hematology Program (www.kidscancer.bc.ca) conducts Phase III clinical<br />

trials <strong>and</strong> has almost 50 North America-wide protocols a year approved under the Children’s Oncology<br />

Group. The team works in close collaboration with the B.C. Cancer Agency in providing treatment <strong>and</strong><br />

follow-up for children with cancer.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

63<br />

Investigators include the following whose details can be found in Appendix 6:<br />

• Davis, Jeffrey H. • Shereck, Evan<br />

• Dix, David B.<br />

• Strahlendorf, Caron<br />

• Rogers, Paul C. • Wu, John K<br />

• Schultz, Kirk R.<br />

Contact:<br />

Rogers, Paul. Medical Director. Tel: 604-875-2322. progers@cw.bc.ca.<br />

Pediatric Rheumatology Program<br />

The Pediatric Rheumatology Program includes both clinical <strong>and</strong> basic research into inflammatory rheumatic<br />

diseases of childhood, with pediatric clinics <strong>and</strong> a transition program for older adolescents <strong>and</strong><br />

young adults with rheumatic diseases. The latter is called the Young Adult Rheumatic Disease (YARD)<br />

Clinic (www.bcchildrens.ca/Services/SpecializedPediatrics/Rheumatology/default.htm).<br />

The Program is involved in clinical <strong>and</strong> translation research focused on pediatric rheumatic diseases<br />

including chronic arthritis, systemic lupus erythematosus <strong>and</strong> vasculitis. It also participates in, <strong>and</strong> is involved<br />

in the development of, national <strong>and</strong> international networks <strong>and</strong> patient registries to facilitate this<br />

research (see www.bcchildrens.ca/Services/SpecializedPediatrics/Rheumatology/Research.htm; www.<br />

cfri.ca/our_research/researchers/search_researchers/researcher_detail.aspID=289).<br />

<strong>Clinical</strong> trials investigators include the following whose details can be found in Appendix 6:<br />

• Cabral, David<br />

• Petty, Ross<br />

• Tucker, Lori.<br />

Contact:<br />

Cabral, David. Director of Young Adult Rheumatic Disease (YARD) Clinic. Tel: 604-875-2437. dcabral@<br />

cw.bc.ca.<br />

Provincial Medical Genetics Program<br />

The Provincial Medical Genetics Program is committed to providing high quality genetic health care to<br />

residents of B.C., while participating in <strong>and</strong> contributing actively to research <strong>and</strong> education in the field<br />

of Medical Genetics. The clinic at BCCH is a provincial referral centre <strong>and</strong> is available to families from all<br />

over B.C. <strong>and</strong> the Yukon (www.bcchildrens.ca/Services/MedicalGenetics/default.htm). Current clinical<br />

trials deal with the identification <strong>and</strong> experimental treatment of lysosomal storage diseases. The program<br />

is also an important part of the Canadian Congenital Anomalies Surveillance Network.<br />

Contact:<br />

Clarke, Lorne. Tel: 604-875-2157. lclarke@cw.bc.ca.<br />

Vaccine Evaluation Centre<br />

The Vaccine Evaluation Centre (www.bcchildrens.ca/Research/VaccineEvaluationCentre/) is a leading<br />

centre for applied vaccine research in Canada. The main research themes involve disease burden studies,<br />

vaccine clinical trials, <strong>and</strong> studies to fine tune public immunization programs, including ongoing<br />

assessment of vaccine safety.


64<br />

BRITISH COLUMBIA<br />

The clinical trials unit primarily conducts Phases II, III, <strong>and</strong> IV clinical trials. Studies include populations<br />

from newborn to the elderly. Enrollments range in size from 25 to 300 subjects per study.<br />

The facility has five Principal Investigators as listed below, <strong>and</strong> eight Associate Investigators. Their details<br />

can be found in Appendix 6.<br />

• Bettinger, Julie • Sauve, Laura<br />

• Dobson, Simon • Scheifele, David (Director)<br />

• Kollmann, Tobias<br />

The Vaccine Evaluation Centre functions as a cooperative with investigators sharing a pool of staff <strong>and</strong><br />

expertise. Staffing of the Centre is as follows:<br />

Study Nurses 1<br />

Data Managers/<br />

Coordinators<br />

Research Assistants<br />

3<br />

Pharmacy<br />

Staff<br />

Laboratory<br />

Staff<br />

Admin.<br />

10 2 3 0* 0 4** 3***<br />

* Dispensing of vaccines not required.<br />

** 1 Finance Manager, 2 Field Nursing Managers, 1 secretary<br />

*** 1 Statistician, 2 programmers<br />

Quality control procedures are based on Health Canada <strong>and</strong> FDA regulations. The Unit has extensive<br />

SOPs covering multiple aspects of clinical trials, data management, laboratory practices <strong>and</strong> staff training.<br />

Contact:<br />

Bjornson, Gordean. Tel: 604-875-2422. gbjornson@cw.bc.ca.<br />

Other<br />

Women & Family HIV Centre<br />

The Women <strong>and</strong> Family HIV Centre is a Provincial resource that provides medical care to women,<br />

children <strong>and</strong> youth living with HIV disease in B.C. (no URL). It is jointly sponsored by the Women’s<br />

Health Centre <strong>and</strong> BCCH. The centre has an important priority of preventing the transmission of HIV<br />

from pregnant women to their infants by coordinating a Provincial program of treating the mothers<br />

<strong>and</strong> their infants with antiretroviral medications. These infants <strong>and</strong> all HIV infected children <strong>and</strong> youth<br />

less than 18 years of age receive medical care at the centre (see www.cfri.ca/our_research/researchers/search_researchers/researcher_detail.aspID=41;<br />

http://gateway.nlm.nih.gov/MeetingAbstracts/<br />

maf=102209450.html). The centre is active in clinical research, including novel treatments, vaccines,<br />

<strong>and</strong> diagnostic/ prognostic biomarkers. It is also part of the national surveillance program of the Canadian<br />

Perinatal HIV database, which is reported annually by Public Health Agency of Canada.<br />

Investigators include the following whose details can be found in Appendix 6:<br />

• Burdge, David<br />

• Forbes, John (Jack).<br />

Contact:<br />

Forbes, John (Jack). Medical Director. Tel: 604-875-2212. jforbes@cw.bc.ca.


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65<br />

B.C. Women’s Hospital<br />

Obstetric Medicine Program<br />

This program provides inpatient <strong>and</strong> outpatient consultative services to both high <strong>and</strong> low risk obstetrics<br />

(http://www.bcwomens.ca/ForProfessionals/<strong>Clinical</strong>Practice/SpecializedWomensHealth/<br />

Obstetric+Medicine.htm). The active research program focuses on the hypertensive disorders of pregnancy<br />

<strong>and</strong> diabetes.<br />

<strong>Clinical</strong> trials investigators include the following whose details can be found in Appendix 6:<br />

• Liston, Rob<br />

• Magee, Laura<br />

• Thompson, David.<br />

Contact:<br />

Magee, Laura. Senior Clinician Scientist. Tel: 604-875-2424 x 6012. lmagee@cw.bc.ca.<br />

Maternal Fetal Medicine Research Unit<br />

The Maternal Fetal Medicine Research Unit (no URL) conducts trials on drug therapy, biomarkers, management<br />

of labour <strong>and</strong> delivery, as well as conducting technology assessments. It is a member of the<br />

North American Fetal Therapy Network (www.naftnet.org).<br />

The staffing at the Maternal Fetal Medicine Research Unit is as follows:<br />

Research Project Research Assistants<br />

Data Managers/ Pharmacy Staff Laboratory Staff Admin.<br />

Coordinators/<br />

Managers 1<br />

3<br />

Coordinators*<br />

5 8 3 0 1 1 Manager<br />

1 Admin. assistant<br />

* Includes two systems analysts/database managers; one statistician<br />

It uses the Women’s Hospital pharmacy in its conduct of clinical trials.<br />

There are 13 investigators in the Maternal Fetal Medicine Research Unit. Details on those who conduct<br />

clinical trials can be found in Appendix 6:<br />

• Butler, Blair<br />

• Magee, Laura (Associate Member)<br />

• Dahlgren, Leanne<br />

• Marquette, Gerry<br />

• Delisle, Marie France<br />

• Mayer, Chantal<br />

• Gagnon, Alain<br />

• Money, Deborah<br />

• Janssen, Patti (Associate Member) • Skoll, Am<strong>and</strong>a<br />

• Lim, Ken<br />

• von Dadelszen, Peter<br />

• Liston, Robert<br />

Contact:<br />

Gagnon, Alain. agagnon@cw.bc.ca.


66<br />

BRITISH COLUMBIA<br />

FRASER HEALTH AUTHORITY<br />

Burnaby Hospital Regional Cancer Centre<br />

Burnaby Hospital Regional Cancer Centre is a community oncology site that provides cancer treatment<br />

(http://research.fraserhealth.ca/clinical_trials/clinical_trials_research_groups/). It conducts Phases II <strong>and</strong><br />

III clinical trials with novel agents as well as exp<strong>and</strong>ed access <strong>and</strong> supportive care studies. In addition to<br />

sponsor-initiated studies, the Centre is also involved in investigator-initiated trials. It has one Principal<br />

Investigator (Lam, Wendy), whose details can be found in Appendix 6, <strong>and</strong> two co-investigators (Stuart,<br />

David; Yu, Simon). Staff include the following:<br />

Study Nurses/ Coordinators<br />

1<br />

Data Managers/ Coordinators<br />

Pharmacy Staff Laboratory Staff Admin<br />

4 1 2* 2* 4<br />

* Available for research projects<br />

The division sees about 500 new patients per year. For new studies, protocols are reviewed by the<br />

Research Coordinator <strong>and</strong> Centre Manager, along with any departments (i.e.. lab, pharmacy, radiology)<br />

that will be utilized. They are then submitted to the Fraser Health REB for approval.<br />

With a fully trained Research Coordinator, all studies comply with ICH/ Good <strong>Clinical</strong> Practice guidelines.<br />

Contact:<br />

Tkachuk, Ryan. BSc. Research Coordinator: Tel: 604-836-5340. tkservices@shaw.ca.<br />

Cardiology <strong>Clinical</strong> <strong>Trials</strong> Inc., Surrey Memorial Hospital<br />

Surrey Memorial Hospital Cardiology <strong>Clinical</strong> <strong>Trials</strong> Inc. (http://research.fraserhealth.ca/clinical_trials/<br />

clinical_trials_research_groups/) conducts both inpatient <strong>and</strong> outpatient Phases II, III, IV clinical trials in<br />

the areas of:<br />

• Acute Coronary Syndromes (hospitalization with heart attack/angina)<br />

• Congestive Heart Failure (acute in hospital as well as outpatient studies)<br />

• Lipid lowering treatments (patients with high cholesterol)<br />

• Cardiovascular disease <strong>and</strong> diabetes combined.<br />

Most of these studies are for novel drugs aimed at preventing heart attacks <strong>and</strong> strokes. The Unit also<br />

participates in a registry <strong>and</strong> a quality of life initiative for acute coronary syndrome. On average there<br />

are 15 studies ongoing at various stages at any given time.<br />

The research group consists of the following eight cardiologists whose details are listed in Appendix 6:<br />

• Bon, Richard<br />

• Manyari, Dante<br />

• Cheung, Stephen • Pearce, Stephen<br />

• Dong, Raymond • Shariff, Salima<br />

• Kornder, Jan<br />

• Tan, Peter


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

67<br />

Staffing is as follows:<br />

Study Nurses 1 Data Entry Clerk Pharmacy Staff Laboratory Staff Admin<br />

4 (2 full time/ 2 1 0 0 3*<br />

part time)<br />

* 1 Manager (who is also one of the study nurses), 1 Assistant, 1 Financial Director.<br />

The unit uses the hospital pharmacy in its conduct of clinical trials if necessary. Laboratory tests are<br />

conducted at the hospital or private laboratories.<br />

Quality control/ assurance procedures are based on detailed <strong>and</strong> extensive St<strong>and</strong>ard Operating Procedures<br />

<strong>and</strong> are compliant with ICH, Health Canada, <strong>and</strong> FDA Good <strong>Clinical</strong> Practice (GCP) guidelines.<br />

All projects are approved by the REB prior to initiation <strong>and</strong> all research staff are trained appropriately in<br />

clinical trials, GCP regulations <strong>and</strong> guidelines, <strong>and</strong> the SOPs. The Unit also participates in monitor <strong>and</strong><br />

study termination visits <strong>and</strong> audits.<br />

Contact:<br />

Breakwell, Lynn. RN. Tel: 604-587-3720. lynn.breakwell@fraserhealth.ca.<br />

Fraser Health Critical Care Group<br />

Critical Care research in Fraser Health is conducted at Surrey Memorial (SMH) <strong>and</strong> Royal Columbian<br />

(RCH) Hospitals (http://research.fraserhealth.ca/clinical_trials/clinical_trials_research_groups/). The<br />

focus of the research program is on contributing to publicly funded trials, [e.g. Thromboprophylaxis;<br />

ARDS; Sedation management, <strong>Life</strong> support outcomes for Octogenarians; Ventilator Associated Pneumonia;<br />

H1N1] largely in collaboration with the highly successful Canadian Critical Care <strong>Trials</strong> Group. Other<br />

research includes industry funded studies [e.g. Sepsis; Surfactant in Acute Lung Injury; Novel Vasopressors]<br />

<strong>and</strong> small investigator driven pilot studies [e.g. Topical antibiotics to reduce central line infections,<br />

dosing of antibiotics in non dialysis dependent renal failure]. Industry-sponsored trials include Phases II<br />

<strong>and</strong> III.<br />

The key Principal Investigators are:<br />

• Reynolds, Steven (Intensivist <strong>and</strong> ICU Research Director, Royal Columbian Hospital)<br />

• Keenan, Sean.<br />

Their details can be found in Appendix 6.<br />

Contact:<br />

Svetik, Miroslav. ICU RCH Research Coordinator. miroslav.svetik@fraserhealth.ca.<br />

Mans, Sheilagh. ICU SMH Research Coordinator. Sheilagh.Mans@fraserhealth.ca.<br />

Multiple Sclerosis Clinic<br />

Based at Burnaby Hospital, the Fraser Health Multiple Sclerosis clinic provides a comprehensive, community<br />

based clinic to the Fraser Health region (http://research.fraserhealth.ca/clinical_trials/clinical_trials_research_groups/).<br />

The clinic has 13 multidisciplinary team members (4 neurologists, urologist,<br />

neuro-ophthalmologist, psychiatrist, rehab medicine, MS certified nurse, physical therapist, occupa-


68<br />

BRITISH COLUMBIA<br />

tional therapist, social worker <strong>and</strong> clinical counselor) <strong>and</strong> 3,000 patients. It also runs a research program<br />

in clinical trials, health service delivery <strong>and</strong> epidemiology.<br />

The clinic was accredited in May 2005 as a full member of the Consortium of Multiple Sclerosis Centres,<br />

a North American multi-disciplinary organization providing networking for all health care professionals<br />

specializing in the care of multiple sclerosis patients.<br />

Contact:<br />

Vorobeychik, Galina. Principal Investigator <strong>and</strong> Clinic Director. Tel: 604 412-6405. galina.vorobeychik@<br />

fraserhealth.ca.<br />

Orthopedics Department<br />

The Orthopedic Department at Royal Columbian Hospital conducts Phases II <strong>and</strong> III clinical trials in<br />

a wide range of pathologies (http://research.fraserhealth.ca/clinical_trials/clinical_trials_research_<br />

groups/). Investigators include:<br />

• McCormack, Robert<br />

• Perey, Bertr<strong>and</strong><br />

• Stone, Trevor<br />

Contact:<br />

Zomar, Mauri. Research Coordinator, Orthopedic Research Office. Tel: 604-520-4855. Mauri.Zomar@<br />

fraserhealth.ca.<br />

Ridge Meadows Hospital<br />

Ridge Meadows Hospital has been actively participating in clinical research for 20 years (http://research.<br />

fraserhealth.ca/clinical_trials/clinical_trials_research_groups/). Beginning with the GUSTO trial early in<br />

the thrombolytic era to the present research involving thrombin receptor antagonists <strong>and</strong> novel heart<br />

failure therapies, cardiac research has been the main focus at the site. Other research topics have included<br />

antibiotics in pneumonia, asthma <strong>and</strong> COPD.<br />

Principal Investigators include the following, whose details can be found in Appendix 6.:<br />

• Auersperg, Edward<br />

• Ervin, Frank<br />

• Tsui, Winston.<br />

The clinical trials group has two coordinators.<br />

Contact:<br />

Ervin, Frank. Tel: 604-466-8199. flervin@telus.net.


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69<br />

INTERIOR HEALTH AUTHORITY<br />

Kidney Clinic<br />

The Kidney Clinic is located at Royal Inl<strong>and</strong> Hospital in Kamloops <strong>and</strong> is affiliated with the B.C. Renal<br />

Agency (http://www.bcrenalagency.ca/kidneysvcs/KidneyServicesRegion/InteriorHealth/chronicClinics.<br />

htm). It conducts Phase III trials on patients undergoing hemodialysis <strong>and</strong> others with end stage renal<br />

disease.<br />

The main investigator is Dr. ECR Wijeyesinghe.<br />

Contact:<br />

Pennington, Carrie Mae. Manager. Tel: 250-314-2849.<br />

Penticton Regional Hospital Research Department<br />

Investigators at the Penticton Regional Hospital Research Department conduct Phases II <strong>and</strong> IV industry-sponsored<br />

<strong>and</strong> grant funded clinical trials in cardiology, neurology, nephrology, gynecology, pediatrics,<br />

oncology, rheumatology. The department has no separate URL. Investigators include:<br />

Cardiology Gynecology Neurology Nephrology<br />

Ashton, T Goncalves, Jose Novak, D Forzley, Brian<br />

Clevel<strong>and</strong>, D<br />

Dyck, Chad<br />

Oncology Pediatrics Rheumatology<br />

Mirch<strong>and</strong>ani, D Gross, Katherine Offer, R<br />

In addition to the investigators, the Department has 10 other staff:<br />

Study Nurses 1 Data Manager/ Coordinator Pharmacy/ Lab Staff Admin.<br />

7 1 0 2 *<br />

* 1 Manager, 1 Admin. Assistant.<br />

The hospital laboratory is used for clinical trials; the pharmacy is rarely required.<br />

Study approval involves a review by the In-Hospital Research Committee for operational impact. Once<br />

this Committee approves the study, it is sent to the Interior Health REB for approval. As per REB <strong>and</strong><br />

sponsor requirements, all studies comply with Health Canada, FDA, <strong>and</strong> ICH GCP regulations <strong>and</strong> guidelines.<br />

Contact:<br />

Valley, Susan. Coordinator <strong>Clinical</strong> Research. Tel: 250-492-4000 x 2629. Susan.Valley@interiorhealth.ca.


70<br />

BRITISH COLUMBIA<br />

PROVIDENCE HEALTH CARE SOCIETY 4<br />

St. Paul’s Hospital<br />

St. Paul’s Hospital is an acute care, teaching, <strong>and</strong> research hospital located in downtown Vancouver<br />

(www.providencehealthcare.org/info_stpauls_main.html). It is home to many world-class medical <strong>and</strong><br />

surgical programs, including cardiac services, HIV/AIDS <strong>and</strong> kidney care. St. Paul’s serves both the local<br />

community <strong>and</strong> patients from across B.C. <strong>and</strong> the Yukon. It houses three CTUs that are described below.<br />

Information on its health research centres can be found in Appendix 9.<br />

AIDS Research Program<br />

The AIDS Research Program (www.cfenet.ubc.ca/content.phpid=18) is affiliated with the B.C. Centre<br />

for Excellence in HIV/AIDS. It conducts clinical trials <strong>and</strong> observational studies in persons with Human<br />

Immunodeficiency Virus (HIV), Hepatitis C Virus (HCV) – HIV coinfection, <strong>and</strong> fungal infection.<br />

The Unit conducts Phases II, III, <strong>and</strong> IV clinical trials. They accrue 100 – 200 patients per year.<br />

The Centre has five Principal Investigators as listed below <strong>and</strong> seven Associate Investigators. Their details<br />

can be found in Appendix 6.<br />

• Barrios, Rol<strong>and</strong>o • Phillips, Peter<br />

• Guillemi, Silvia • Tyndall, Mark<br />

• Montaner, Julio<br />

Program staffing is as follows:<br />

Study Nurses/ Coordinators<br />

1<br />

Research (<strong>Clinical</strong> Pharmacy Staff Laboratory Staff Administration<br />

<strong>Trials</strong>) Asst. 3<br />

3 * 1 0 0 2**<br />

* The study (clinical trials) coordinators also perform data entry activities (in source documents <strong>and</strong> CRFs) as part of their role.<br />

** 1 Admin. Coordinator (operational manager); 1 Accountant.<br />

The process for getting trials approved in this unit is as detailed below:<br />

a) Submission of the Study Protocol <strong>and</strong> other required documents by the <strong>Clinical</strong> <strong>Trials</strong> Assistant to the<br />

Providence Health Research Ethics Board for review <strong>and</strong> approval.<br />

b) <strong>Clinical</strong> <strong>Trials</strong> Assistant requests the different departments (e.g., Laboratory, Pharmacy, Radiology, etc.)<br />

involved in this study for approval. Approval letters from the different department are then submitted<br />

to the Offices of Research Services.<br />

c) Contract personnel at the Offices of Research Services ensures the contract has been approved <strong>and</strong><br />

signed.<br />

d) The Offices of Research Services then releases the Certificate of Final Approval.<br />

Quality control/ assurance procedures are based on St<strong>and</strong>ard Operating Procedures (SOPs). The SOPs<br />

cover all study-related functions <strong>and</strong> responsibilities <strong>and</strong> reflect ICH <strong>and</strong> federal regulations . SOPs are<br />

updated as necessary. Staff members are provided training on a regular basis to the site-specific SOPs<br />

<strong>and</strong> GCP protocols. All projects are approved by the REB prior to initiation.<br />

Contact:<br />

Chau, William. Tel: 604-806-8064. wchau@cfenet.ubc.ca.<br />

4<br />

Providence is an independent legal entity aligned with VCH for operational purposes.


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71<br />

CIHR Canadian HIV <strong>Trials</strong> Network (CTN)<br />

The CIHR Canadian HIV <strong>Trials</strong> Network (CTN) (www.hivnet.ubc.ca) is a national organization with the<br />

centre based out of St. Paul’s Hospital. The CTN provides a national <strong>and</strong> regional infrastructure to facilitate<br />

clinical trials in HIV/AIDS, employing managers, statisticians, data methodologists, <strong>and</strong> communications<br />

officers at the Vancouver national centre. Services include development of a clinical trial from first<br />

concept to final protocol, as well as management of all aspects of a trial. Study sites providing the subjects<br />

for clinical trials are located across Canada. There are five sites located in B.C. (1 St. Paul’s Hospital, 2<br />

downtown Vancouver, 1 Victoria, 1 Kelowna). The CTN coordinates <strong>and</strong> manages all these sites – it does<br />

not recruit patients at its own centre.<br />

The CTN sites conduct Phases II, III <strong>and</strong> IV clinical trials. In 2008/9 they accrued 417 patients.<br />

The National Director of the Network is Dr. Martin Schechter, whose details can be found in Appendix<br />

6. He works with 34 Principal Investigators <strong>and</strong> 85 associate investigators across Canada The Network’s<br />

structure in the Vancouver national centre is shown in Figure A6.<br />

The national network has a staff of 47 across Canada. Network staffing in the Vancouver national centre<br />

is as follows:<br />

Project Managers<br />

Study Coordinators<br />

4 (40 across<br />

Canada)<br />

<strong>Clinical</strong> <strong>Trials</strong><br />

Assistant<br />

Data Managers<br />

Data Entry<br />

Pharmacy/<br />

Lab Staff<br />

Other<br />

1 3 2 0 19*<br />

* 1 Chief Scientific Officer, 2 Health Economists, 2 IT technicians (part-time), 4 statisticians, 3 database programmers, 3 communications<br />

staff, 4 administrative staff (accounting, contracts, receptionists, general support).<br />

For trial approval, Network investigators must apply to the Network using a Study Proposal Application<br />

Form. The protocol <strong>and</strong> informed consent forms are developed using the Network’s Protocol, Protocol<br />

Outline <strong>and</strong> Model Informed Consent templates. New studies are reviewed by the Scientific Review<br />

Committee <strong>and</strong> the Community Advisory Committee; these committees offer their reviews to the<br />

Executive Management Committee who make the final decision to approve a new Network supported<br />

study.<br />

FIGURE A6. CIHR Canadian HIV <strong>Trials</strong> Network<br />

Martin Schechter / Aslam Anis<br />

National Directors<br />

Jim Pankovich<br />

CSO<br />

Joel Singer<br />

Head of D&M<br />

David Cox<br />

CAO<br />

Data & Methodology<br />

Finance & Admin<br />

(includes HR & IT)<br />

Pharmaeconomics<br />

Communications &<br />

Information<br />

Project Management<br />

Postdoctoral Fellows<br />

International


72<br />

BRITISH COLUMBIA<br />

Quality control/ assurance procedures are based on extensive St<strong>and</strong>ard Operating Procedures compliant<br />

with Good <strong>Clinical</strong> Practice (GCP) guidelines. The CTN also trains clinical trial personnel in GCP <strong>and</strong><br />

clinical trial procedures in addition to monitoring all clinical trials. All projects are approved by the REB<br />

prior to initiation.<br />

Contact:<br />

Pankovich, Jim. Chief Scientific Officer. Tel: 604-806-8340. jpankovich@mail.hivnet.ubc.ca.<br />

Emergency Medicine Research Group<br />

St Paul’s Emergency Medicine Research Group is a nationally recognized group of researchers (www.<br />

sphemerg.ca/research). Currently led by Dr. Robert Stenstrom, the group is involved in research in infectious<br />

diseases (SSTI, Sepsis), Stroke Care, Patient Safety <strong>and</strong> Medical Decision Making, <strong>and</strong> Educational<br />

Research.<br />

Investigators who conduct clinical trials include the following whose details are contained in<br />

Appendix 6:<br />

• Grafstein, Eric • Harris, Devin • Stenstrom, Robert<br />

Contact:<br />

Stenstrom, Robert. Research Director. Tel: 604-682-2344 x 68985. robstenstrom@shaw.ca.<br />

Foot <strong>and</strong> Ankle Clinic Orthopedics Research Group<br />

The Foot <strong>and</strong> Ankle Clinic is based at St Paul’s Hospital (www.bcfoot<strong>and</strong>ankle.com/research.htm). The<br />

primary research objective of the B.C. Foot <strong>and</strong> Ankle Clinic Orthopedics Research Group is to better underst<strong>and</strong><br />

the results of the various surgical techniques used to treat a variety of foot <strong>and</strong> ankle ailments.<br />

Investigators include the following whose details are contained in Appendix 6:<br />

• Younger, Alastair (Head)<br />

• Yang, Tung Chuo<br />

• Smith, Donna<br />

The clinical research group has six co-investigators, a Research Coordinator/Manager, <strong>and</strong> three research<br />

assistants.<br />

Contact:<br />

Bora, Biraj. <strong>Clinical</strong> Research Coordinator. Tel: 604-806-8743.<br />

Heart Centre<br />

St. Paul’s Heart Centre (www.heartcentre.ca) provides complete care for British Columbians with all<br />

kinds of heart disease. Services include heart disease prevention <strong>and</strong> reversal, a variety of diagnostic<br />

services <strong>and</strong> a full spectrum of treatment <strong>and</strong> care, including surgery, transplants <strong>and</strong> rehabilitation.


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73<br />

The Heart Centre encompasses a number of different groups, of which the following conduct of<br />

clinical trials:<br />

• The Healthy Heart Program<br />

• Interventional Cardiology<br />

• Atrial Fibrillation/ Arrythmia Device<br />

• Cardiovascular Surgery Research<br />

• Heart Failure <strong>and</strong> Acute Coronary Research<br />

<strong>Clinical</strong> trials include those pertaining to angioplasty <strong>and</strong> the use of stents, cardiac failure, heart transplant,<br />

other heart surgery, prevention of heart disease, <strong>and</strong> the use of novel drugs. Investigators conduct<br />

Phases I, II, <strong>and</strong> III trials <strong>and</strong> include those 25 listed below. Their details can be found in Appendix 6:<br />

• Abel, James • Hamburger, Jaap • Sirrs, S<strong>and</strong>ra<br />

• Cheung, Anson • Ignaszewski, Andrew • Straatman, Lynn<br />

• Aymong, Eve • Kerr, Charles • Tung, Stanley<br />

• Bondy, Gregory • Lichtenstein, Samuel • Ur, Ehud<br />

• Bowering, John • Mancini, John • Webb, John<br />

• Carere, Ron • Moss, Robert • Ye, Jian<br />

• Chan, Sammy • Rabkin, Simon • Yeung, John<br />

• Francis, Gordon • Ramanathan, Krishnan<br />

• Fung, Anthony Y-F • Ricci, Donald<br />

Contact:<br />

See www.heartcentre.ca/clinics.asp.<br />

Hematology Research Group<br />

The Hematology Research Group at St. Paul’s Hospital investigates a broad range of blood conditions<br />

including both benign <strong>and</strong> malignant disorders of blood proteins <strong>and</strong> blood cells (www.providencehealthcare.org/Dept_of_Medicine/researchers.html).<br />

Areas of research include: Myelodysplastic Syndromes,<br />

Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Idiopathic<br />

Thrombocytopenic Purpura, Lymphoma in HIV patients, Hemophilia <strong>and</strong> Thrombosis.<br />

The group has five investigators, including:<br />

• Vickars, Linda<br />

• Leitch, Heather.<br />

Details on these two investigators are contained in Appendix 6. There are four research study staff.<br />

Contact:<br />

Leitch, Heather. Director. Tel: 604 684-5794. hleitch@providencehematology.com.<br />

James Hogg iCAPTURE Centre<br />

The iCAPTURE Centre houses over 250 researchers at St. Paul’s Hospital, who conduct research into the<br />

mechanisms, prevention, diagnosis <strong>and</strong> treatment of heart, blood vessel <strong>and</strong> lung diseases (www.icapture.ubc.ca).<br />

Activities include clinical trials as well as basic <strong>and</strong> translational research <strong>and</strong> postdoctoral<br />

training.


74<br />

BRITISH COLUMBIA<br />

<strong>Clinical</strong> trials investigators include the following, whose details can be found in Appendix 6:<br />

• Bai, Tony<br />

• McManus, Bruce<br />

• Dorscheid, Delbert • Pare, Peter<br />

• Frohlich, Jiri<br />

• Russell, James<br />

• Hill, John<br />

• Schellenberg, R Robert<br />

• Hogg, James<br />

• Sin, Don<br />

• Knight, Darryl • van Eeden, Stephan F.<br />

• Man, Paul<br />

Contact:<br />

Hansen, Melanie. Tel: 604-806-9299. Melanie.Hansen@hli.ubc.ca.<br />

Pacific Lung Health Centre<br />

The Pacific Lung Health Centre is an academic clinical program located at St. Paul’s Hospital, dedicated<br />

to the care for patients with lung disease (www.pacificlung.com). The Centre has research associations<br />

with a number of major UBC research facilities (www.ubc.ca), including the James Hogg iCAPTURE<br />

Centre for Cardiovascular <strong>and</strong> Pulmonary Research (www.icapture.ca), as well as the Centre for Health<br />

Evaluation <strong>and</strong> Outcome Studies (www.cheos.ubc.ca).<br />

The Pacific Lung Research Centre is currently conducting clinical trials in various respiratory disease<br />

areas, including Chronic Obstructive Pulmonary Disease (Bronchitis <strong>and</strong> Emphysema), Interstitial Pulmonary<br />

Fibrosis, Chronic Cough, Cystic Fibrosis, Asthma <strong>and</strong> other areas.<br />

Investigators include the following whose details are contained in Appendix 6:<br />

• Bai, Tony<br />

• Schellenberg, R Robert<br />

• Lawson, Lindsay • Sin, Don<br />

• Levy, Robert • van Eeden, Stephan F.<br />

• Man, Paul<br />

• Tan, Wan-Cheng<br />

• Nakielna, Barbara • Wilcox, Pearce<br />

• Pare, Peter<br />

Contact:<br />

Tel: 604 806-9465. info@pacificlung.com.


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75<br />

VANCOUVER COASTAL HEALTH<br />

Vancouver General Hospital<br />

Vancouver General Hospital (VGH) is one of Canada’s largest teaching <strong>and</strong> research hospitals. <strong>Clinical</strong><br />

research at VGH (<strong>and</strong> UBC Hospital, described below) is conducted by the Vancouver Coastal Health<br />

Research Institute (VCHRI) (www.vchri.ca), a partnership between Vancouver Coastal Health Authority<br />

<strong>and</strong> the University of British Columbia.<br />

Arthritis Research Centre<br />

The Arthritis Research Centre of Canada is affiliated with the Vancouver Coastal Health Research<br />

Institute <strong>and</strong> UBC (www.arthritisresearch.ca). It conducts clinical research <strong>and</strong> trials related to arthritis<br />

diagnosis, prognosis, prevention, care outcomes, <strong>and</strong> quality of life issues. It has a clinical trials group<br />

with at least three coordinators.<br />

Contact:<br />

Ellis, Nancy. Senior <strong>Clinical</strong> <strong>Trials</strong> Coordinator. Tel: 604-871-4573.<br />

See also Appendix 9, part 7.<br />

B.C. Centre for Stroke <strong>and</strong> Cerebrovascular Diseases<br />

Located at VGH, the B.C. Centre for Stroke <strong>and</strong> Cerebrovascular Diseases takes a multidisciplinary approach<br />

to stroke care, research, <strong>and</strong> education (www.bcstrokecentre.ca). The Centre offers 24/7 care<br />

for stroke victims <strong>and</strong> conducts Phases I, II, <strong>and</strong> III clinical trials. It is directed by Dr Phil Teal. His details<br />

can be found in Appendix 6. The clinical trials group is comprised of a small team of Stroke Neurologists,<br />

Neuro-Interventionalists <strong>and</strong> Research Coordinators that are involved in multiple acute stroke <strong>and</strong><br />

stroke prevention trials.<br />

<strong>Clinical</strong> trials include the testing of novel drugs for the acute treatment of strokes <strong>and</strong> prevention of<br />

secondary strokes.<br />

Contact:<br />

Teal, Phil. Director. Tel: 604-875-5295. teal@interchange.ubc.ca.<br />

Cardiology Research<br />

VGH Cardiology Research is an integral part of the VGH/UBC Division of Cardiology. Members of the Division<br />

all participate <strong>and</strong> function as a team for trial recruitment <strong>and</strong> follow-up. The Cardiology Research<br />

clinical trials unit conducts Phase IIa, IIb, <strong>and</strong> III industry-sponsored clinical trials, as well as registries <strong>and</strong><br />

investigator-initiated studies. <strong>Trials</strong> include those investigating new drugs, new indications for established<br />

drugs, devices, <strong>and</strong> treatment strategies (NIH sponsored). Subjects are recruited from the Coronary<br />

Care Unit, Cardiac Catheterization Laboratory <strong>and</strong> out-patient cardiology clinics. Several hundred<br />

patients are enrolled annually. The unit has no independent URL.


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BRITISH COLUMBIA<br />

The facility has 13 investigators as listed below. Their details can be found in Appendix 6.<br />

• Fung, Anthony • Saw, Jackie<br />

• Gin, Ken<br />

• Ramanathan, Krishnan<br />

• Hamburger, Jaap • Ricci, Donald<br />

• Isserow, Saul<br />

• Virani, Sean<br />

• Jue, John<br />

• Wong, Graham<br />

• Lee, P.K.<br />

• Wood, David<br />

• Nair, Parvathy<br />

Staffing of the unit is as follows:<br />

Study Nurses/<br />

Coordinators 1<br />

Research Assistants<br />

3<br />

Data Managers/<br />

Coordinators<br />

Pharmacy Staff Laboratory Staff Administration<br />

(Manager)<br />

7* 2** 0 * 0 0 1 (parttime)***<br />

* All the study nurses/ coordinators (called research coordinators) also h<strong>and</strong>le data. In addition, 1 designs project databases <strong>and</strong><br />

provides statistical <strong>and</strong> IT support<br />

** 1 h<strong>and</strong>les regulatory documents <strong>and</strong> finances; 1 h<strong>and</strong>les specimens <strong>and</strong> provides other clinical support functions.<br />

*** The manager is one of the research coordinators.<br />

The unit uses Vancouver General Hospital pharmacy in its conduct of in-patient clinical trials when<br />

applicable. <strong>Clinical</strong> laboratory tests use the VGH Hospital Laboratory <strong>and</strong>/or are shipped to central laboratories<br />

provided by the trial. Hospital research-designated staff in both pharmacy <strong>and</strong> laboratory have<br />

been essential.<br />

Quality control procedures are based on:<br />

• St<strong>and</strong>ard Operating Procedures for ‘Consenting’ & ‘Adverse Events’<br />

• Following <strong>and</strong> maintaining the Good <strong>Clinical</strong> Practice (GCP), ICH regulations <strong>and</strong> guidelines of<br />

Health Canada <strong>and</strong> the FDA<br />

• Regularly attended education, study meetings, <strong>and</strong> on-line training of GCP provided by the local<br />

clinical Research Ethics Board <strong>and</strong> other programs. All staff have been certified in NIH Human<br />

Protection.<br />

All projects are approved by the REB prior to initiation.<br />

Contact:<br />

Fox, Rebecca. Manager. Tel: 604-875-4065. r.fox@telus.net.<br />

Centre for Menstrual Cycle <strong>and</strong> Ovulation Research<br />

Part of the Vancouver Coastal Health Research Institute, the Centre for Menstrual Cycle <strong>and</strong> Ovulation<br />

Research (www.cemcor.ubc.ca) is the only centre in North America that focuses on ovulation <strong>and</strong> the<br />

causes for <strong>and</strong> consequences of ovulation disturbances. The Centre Director is Jerilynn C. Prior, whose<br />

details can be found in Appendix 6.<br />

The Centre’s clinical trials are investigator-initiated <strong>and</strong> are completely independent of funding sources.<br />

Contact:<br />

Tel: 604–875-5927. cemcor@interchange.ubc.ca.


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77<br />

Dermatology <strong>Clinical</strong> <strong>Trials</strong> Unit<br />

The Dermatology <strong>Clinical</strong> <strong>Trials</strong> Unit at the Skin Care Centre of UBC <strong>and</strong> VGH, conducts investigator-initiated<br />

<strong>and</strong> industry-sponsored clinical trials in all of the major therapeutic areas of dermatology, including<br />

acne, psoriasis, eczema, warts, skin cancer, <strong>and</strong> hair disorders (www.derm.ubc.ca/research/clinical_<br />

trials_unit.htm). The unit covers the full spectrum of clinical studies from Phase I through IV in medicine,<br />

surgery, <strong>and</strong> cosmetics. The Skin Care Centre accommodates over 80,000 patient visits each year.<br />

Dedicated clinical trial facilities include: two examination rooms, a monitor’s room (equipped with a<br />

telephone, internet connection <strong>and</strong> photocopier/printer), an administration office, a trial coordinators’<br />

office, a secure supplies room for CRF storage, double-locking medication storage cupboards, refrigeration<br />

unit <strong>and</strong> a –40°C freezer for sample storage.<br />

Principal Investigators include the following, whose details can be found in Appendix 6:<br />

• Dutz, Jan<br />

• Rivers, Jason<br />

• Ho, Vincent<br />

• Shapiro, Jerry<br />

• Lui, Harvey<br />

• Zhou, Youwen<br />

• Prendiville, Julie<br />

Staff include three full-time clinical research coordinators <strong>and</strong> one part-time nurse.<br />

Quality control procedures are based on St<strong>and</strong>ard Operating Procedures <strong>and</strong> Good <strong>Clinical</strong> Practice<br />

guidelines of Health Canada <strong>and</strong> the FDA. All projects are approved by the REB prior to initiation.<br />

Contact:<br />

Lui, Harvey. Tel: 604 875-4747. harvey.lui@ubc.ca.<br />

Downtown Infectious Diseases Clinic<br />

The Downtown Infectious Diseases Clinic is part of the University of British Columbia, Department of<br />

Anesthesiology, Pharmacology <strong>and</strong> Therapeutics. It is located away from the main Vancouver General<br />

Hospital site, in downtown Vancouver near to St Paul’s Hospital. The Downtown Infectious Diseases<br />

Clinic works with many other clinics including the Pender Community Health Centre ( a clinic in Vancouver<br />

Downtown Eastside) <strong>and</strong> Yale Medical Centre (a privately-run methadone clinic in downtown<br />

Vancouver). Several CIHR Canadian HIV <strong>Trials</strong> Network studies are conducted at the Clinic.<br />

The Clinic primarily conducts Phases II, III, <strong>and</strong> IV clinical trials, as well as investigator-initiated studies,<br />

mainly with HIV <strong>and</strong> HCV patients. Studies accrue approximately 40 patients per year (40% of the estimated<br />

100 new patients seen at the clinic per year). The clinic also has approximately 1,000 registered<br />

patients. It has no independent URL.<br />

The facility has three Principal Investigators as listed below. Their details can be found in Appendix 6.<br />

• Conway, Brian<br />

• Alenezi, Osamah<br />

• Reynolds, Robert


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BRITISH COLUMBIA<br />

Staffing of the Centre is as follows:<br />

Study Nurses/<br />

Coordinators 1<br />

Research Assistants<br />

3<br />

Data Managers/<br />

Coordinators<br />

Pharmacy<br />

Staff<br />

Laboratory<br />

Staff<br />

Admin.<br />

6* 4 0 0 2 (part-time) 2** 2***<br />

* 4 coordinators; 2 nurses.<br />

** 1 project manager, 1 CTU manager.<br />

*** 1 statistician, 1 IT technician.<br />

IT/ Statistics<br />

<strong>Clinical</strong> trials are conducted at the clinic, which also uses external laboratories, hospitals <strong>and</strong> pharmacies<br />

in its conduct of trials. It has a laboratory at UBC, as well as its own laboratory space.<br />

Quality control/ assurance procedures are based on extensive St<strong>and</strong>ard Operating Procedures <strong>and</strong><br />

Good <strong>Clinical</strong> Practice guidelines of Health Canada <strong>and</strong> the FDA. The unit also provides regular training<br />

sessions for researchers <strong>and</strong> staff members in the conduct of clinical studies. All projects are approved<br />

by the REB prior to initiation.<br />

Contact:<br />

Tossonian, Harout. Research Manager. Tel: 604-642-6429 x 304. tossonian@exchange.ubc.ca.<br />

Diabetes Research Centre<br />

The Diabetes Research Centre (http://diabetesresearch.net/) is located next to VGH.<br />

The Principal Investigator <strong>and</strong> Research Director is Dr. Tom Elliott. His details can be found in Appendix<br />

6. The Centre has five clinical trial coordinators. Studies include the testing of novel drugs in patients<br />

with diabetes, diabetes with or at risk of cardiovascular disease.<br />

Contact:<br />

Elliott, Tom. Research Director. Tel: 604-875-5934. tom.elliott@vch.ca.<br />

Epilepsy Clinic<br />

The VGH Epilepsy Clinic is targeted at adults with epilepsy <strong>and</strong> related disorders (http://vch.eduhealth.<br />

ca/PDFs/FM/FM.470.V279.pdf ). It contains both in-patient <strong>and</strong> out-patient components. Principal Investigators<br />

include the following, whose details can be found in Appendix 6:<br />

• Javidan, Mano<br />

• Townsend, Tiffany.<br />

Contact:<br />

Javidan, Mano. Medical Director EEG Lab. Tel: 604 875-4402. manouchehr.javidan@vch.ca.<br />

Hematology Research <strong>and</strong> <strong>Clinical</strong> <strong>Trials</strong> Unit (HRCTU)<br />

The HRCTU is part of the Leukemia/BMT Program of B.C (www.leukemiabmtprogram.org). It conducts<br />

Phases I, II, <strong>and</strong> III clinical trials on all hematologic malignancies <strong>and</strong> also works with stem cells. The Unit<br />

sees approximately 500 new patients each year <strong>and</strong> approximately 100 of these may be suitable for


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

79<br />

clinical trials. It also acts as the data management centre for Canadian Blood <strong>and</strong> Marrow Transplant<br />

multi-institutional clinical trials.<br />

The HRCTU has 12 investigators as follows – most of these are listed in Appendix 6:<br />

• Abou Mourad, Yasser • Power, Maryse<br />

• Barnett, Michael • Shepherd, John<br />

• Hogge, Donna • Smith, Clay<br />

• Nantel, Steve<br />

• Song, Kevin<br />

• Narayanan, Sujaatha • Sutherl<strong>and</strong>, Heather<br />

• Nevill, Tom<br />

• Toze, Cindy<br />

Staffing of the Centre is as follows:<br />

Study Nurses 1 Research Assistants 3 Data Entry/ Coordinators<br />

Pharmacy/ Lab Staff Admin<br />

7* 2** 2 0 1 (<strong>Clinical</strong> Res.<br />

Nurse Supervisor)<br />

* 6 full-time, 1 casual.<br />

** H<strong>and</strong>le samples <strong>and</strong> supplies, invoicing, files set-up, adverse events submissions.<br />

It uses the VGH pharmacy in the conduct of its clinical trials.<br />

Quality control <strong>and</strong> assurance are procedures are based on Good <strong>Clinical</strong> Practice regulations <strong>and</strong><br />

guidelines of the FDA/Health Canada. The division has extensive SOPs <strong>and</strong> provides regular training sessions<br />

for researchers <strong>and</strong> staff members in the conduct of clinical studies.<br />

Contact:<br />

Smith, Clay. Director Leukemia/BMT Program of B.C. Tel: 604-875-4863. clsmith@bccancer.bc.ca.<br />

The Lung Centre<br />

The Lung Centre (http://lungcentre.vch.ca/) specializes in the treatment of pulmonary conditions such<br />

as asthma, emphysema, chronic bronchitis, bronchiectasis, lung cancer, occupational <strong>and</strong> environmental<br />

lung diseases, sarcoidosis, pnuemonia, tuberculosis, pulmonary hypertension <strong>and</strong> interstitial lung<br />

disease. As well as its clinical activities, the Lung Centre also has dedicated research space in which it<br />

conducts multiple research projects.<br />

The clinical trials unit primarily conducts Phases II, III, <strong>and</strong> IV clinical trials, as well as investigator-initiated<br />

studies. Studies accrue approximately 140 patients per year (10% of the estimated 1,440 new patients<br />

seen at the clinic per year).<br />

The facility has 16 investigators as listed below. Their details can be found in Appendix 6. Its structure is<br />

shown in Figure A7.


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BRITISH COLUMBIA<br />

Investigators:<br />

• Ayas, Najib<br />

• Carlsten, Chris<br />

• Cook, Victoria<br />

• FitzGerald, J. Mark<br />

• Fleetham, John<br />

• Lam, Stephen<br />

• Levy, Robert<br />

• Khalil, Nasreen<br />

• McWilliams, Annette<br />

• Ostrow, David<br />

• Road, Jeremy<br />

• Ronco, Juan<br />

• Ryan, Frank<br />

• Swiston, John<br />

• Wilson, Jennifer (Medical Director)<br />

• Yeung, Moira<br />

Lab Staff Admin. Statistician<br />

Staffing of the Centre is as follows:<br />

Study Nurses/ Coordinators<br />

Pharmacy/<br />

1<br />

13 0 1 * 1<br />

* Res. Admin Coordinator (Manager).<br />

The Centre mainly uses the Vancouver Hospital pharmacy <strong>and</strong> laboratories for its clinical trials.<br />

FIGURE A7. The Lung Centre Organizational Chart<br />

Division Head<br />

Dr. FitzGerald<br />

Other Doctors in<br />

Respiratory Division<br />

Director Postgraduate<br />

Training Program<br />

Medical Director<br />

Administrative<br />

Manager Margie Bell<br />

Sr. <strong>Clinical</strong> Research<br />

Manager<br />

Academic Program<br />

Assistant Margie Bell<br />

Clinic Manager<br />

Kelly Sallaway<br />

Divisional Head<br />

Secretary<br />

Other Secretaries<br />

Barb Herbert<br />

Bernice Robillard<br />

Researchers/Research<br />

Coordinators<br />

Ethics/Research Admin<br />

Coordinator Freda Tom<br />

Clinic Staff<br />

Airways Educators<br />

Lab. Technician<br />

Clinic Receptionists<br />

Quality control procedures are based on St<strong>and</strong>ard Operating Procedures <strong>and</strong> Good <strong>Clinical</strong> Practice<br />

guidelines of Health Canada <strong>and</strong> the FDA. The unit also provides regular training sessions for researchers<br />

<strong>and</strong> staff members in the conduct of clinical studies.<br />

Contact:<br />

Tom, Freda. <strong>Clinical</strong> <strong>Trials</strong> Coordinator. Tel: 604-875-4111, x 67916. Freda.Tom@vch.ca.<br />

Nephrology Research Unit/ Group, VGH <strong>and</strong> St Paul’s Hospital<br />

The Division of Nephrology has two sites for its clinics <strong>and</strong> clinical trials unit: St Paul’s Hospital <strong>and</strong><br />

VGH. The following description covers both sites. The nephrology clinics <strong>and</strong> CTU covers patients with<br />

chronic kidney disease, <strong>and</strong> those undergoing dialysis <strong>and</strong> kidney transplantation. The Unit has no


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

81<br />

independent URL but is associated with the B.C. Provincial Renal Agency network (www.bcrenalagency.<br />

ca). The latter is an agency of the PHSA.<br />

The clinical trials unit primarily conducts Phases II, III, <strong>and</strong> IV clinical trials, as well as investigator-initiated<br />

studies. The Division of Nephrology sees approximately 2,000 new patients per year, of which 800 could<br />

be accrued into clinical trials.<br />

FIGURE A8. Division of Nephrology Nov. 2009 <strong>Clinical</strong> Research Organizational Chart<br />

Division Head (Acting)<br />

Dr. David L<strong>and</strong>sberg<br />

VGH Division Head<br />

Dr. J. Jastrzebski<br />

Senior Administrator<br />

Shawn Jorgensen<br />

Education <strong>Clinical</strong> Research<br />

St. Paul’s Hospital UBC VGH<br />

<strong>Clinical</strong> Research<br />

Manager Katy Vela<br />

Project Manager<br />

Sheila O’Donoghue<br />

Transplant Research<br />

Coordinators<br />

<strong>Clinical</strong> Research<br />

Manager Daniel Rogers<br />

Statistical Analysis<br />

Research Coordinators Biostatistician <strong>Clinical</strong> Research<br />

Coordinators<br />

The facility has 18 investigators as listed below. Their details can be found in Appendix 6. Its structure is<br />

shown in Figure A8.<br />

• Beaulieu, M. • Kiaii, M. • Yeung, C.K<br />

• Chiu, A. • L<strong>and</strong>sberg, D. • Jastrzebski, J.<br />

• Copl<strong>and</strong>, M. • Levin, A. • Johnston, O.<br />

• Duncan, J. • Quamme, G. • Wong, N.<br />

• Gill, Jag • Shapiro, R.J. • Keown, P.<br />

• Gill, John • Singh, S. • Zalunardo, N.<br />

Staffing of the Unit is as follows:<br />

Study Nurses/<br />

Coordinators 1<br />

Research Assistants<br />

Data Managers Pharmacy/ Lab<br />

3 Staff<br />

Admin.<br />

Statisticians<br />

7 2 1 0 4* 4<br />

* 2 <strong>Clinical</strong> Research Managers, 1 Project Manager, 1 (0.6 FTE) Finance Administrator.<br />

The Unit uses Vancouver General Hospital pharmacy <strong>and</strong> the hospital laboratories in its conduct of clinical<br />

trials.


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Quality control procedures are based on St<strong>and</strong>ard Operating Procedures <strong>and</strong> Good <strong>Clinical</strong> Practice<br />

guidelines of Health Canada <strong>and</strong> the FDA. The unit also provides regular training sessions for researchers<br />

<strong>and</strong> staff members in the conduct of clinical studies. All projects are approved by the REB prior to<br />

initiation.<br />

Contact:<br />

Rogers, Daniel. Division of Nephrology, <strong>Clinical</strong> Research Manager VGH. Tel: 604-875-4111 x 67679. Daniel.rogers@vch.ca.<br />

Neurosurgery Division, VGH<br />

The VGH Division of Neurosurgery (www.surgery.ubc.ca/neurosurgery) has three Principal Investigator<br />

physicians, one nurse, <strong>and</strong> one research nurse/coordinator who work with patients with cerebrovascular<br />

disease/ stroke. Details about the physicians can be found in Appendix 6.<br />

• Haw, Charles (MD) • Redekop, Gary (MD)<br />

• Heran, Manraj (MD) • Brevner, Anglea (RN)<br />

The division sees about 5,000 new patients per year of which approximately 200 may be eligible for<br />

clinical trials. It conducts Phases II <strong>and</strong> III clinical trials <strong>and</strong> has one clinical trials research nurse. It uses<br />

the Vancouver General Hospital pharmacy <strong>and</strong> laboratory in its conduct of clinical trials, as well as an<br />

external laboratory.<br />

Quality control <strong>and</strong> assurance are procedures are based on SOPs <strong>and</strong> the Good <strong>Clinical</strong> Practice guidelines<br />

of the FDA/Health Canada. The division provides regular training sessions for researchers <strong>and</strong> staff<br />

members in the conduct of clinical studies.<br />

Contact:<br />

Redekop, Gary. Head, Division of Neurosurgery. Tel: 604-875-5235. gary.redekop@vch.ca.<br />

Psychiatry Administration - VGH<br />

The VGH Psychiatry Administration division has four Principal Investigators who work with patients with<br />

mental illness, particularly depression, schizophrenia, <strong>and</strong> addiction. It also has two research nurses/coordinators.<br />

Details about the PIs can be found in Appendix 6.<br />

Principal Investigators<br />

• Ganesan, Soma • Mok, HIram<br />

• Lu, Shaohua<br />

• Singh, Kulbir<br />

The Unit works on Phases III <strong>and</strong> IV clinical trials, as well as investigator-initiated <strong>and</strong> grant funded studies.<br />

It sees approximately 500 new patients per year. It has no independent URL.<br />

Quality control <strong>and</strong> assurance are procedures are based on sponsor SOPs. Researchers <strong>and</strong> staff are<br />

trained in the conduct of clinical studies within VCH.<br />

Contact:<br />

Ganesan, Soma. Tel: 604-875-4023. soma.ganesan@vch.ca.


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83<br />

The Vancouver Prostate Centre<br />

The Vancouver Prostate Centre (www.prostatecentre.com) (www.pctriadd.com) is a world-class research,<br />

translational, <strong>and</strong> clinical facility that works on all aspects of prostate disease including cancer,<br />

bladder problems, <strong>and</strong> kidney disease. The <strong>Clinical</strong> <strong>Trials</strong> Unit resides within this Centre.<br />

The Clinic conducts Phases I, II, III, <strong>and</strong> IV clinical trials, as well as investigator-initiated, National Cancer<br />

Institute of Canada (NCIC), Canadian Urologic Oncology Group (CUOG), <strong>and</strong> Canadian Urology Research<br />

Consortium (CURC) studies. The Clinic sees approximately 1,000 new patients/year. It is able to<br />

enroll 800 – 1,200 patients in clinical trials, depending on eligibility (10-15% of the approximately 8,000<br />

patients registered with the Clinic).<br />

The facility has 13 investigators, whose details can be found in Appendix 6:<br />

• Black, Peter<br />

• Kollmannsberger, Christian<br />

• Chew, Ben<br />

• Nguan, Chris<br />

• Chi, Kim<br />

• Nigro, Mark<br />

• Davison, Joyce • Patterson, Ryan<br />

• Fenster, Howard • So, Alan<br />

• Gleave, Martin E. • Stothers, Lynn<br />

• Goldenberg, Larry<br />

Staffing of the unit is as follows:<br />

Study Nurses/<br />

Coordinators 1<br />

Research Assistants<br />

3<br />

Data Managers/<br />

Coordinators<br />

Pharmacy/ Lab<br />

Staff<br />

Admin<br />

4* 1.5* 0 0 1** 1<br />

* There are 2 coordinators <strong>and</strong> 2 nurses. Also involved in data collection <strong>and</strong> data entry, i.e., perform Data Manager/Coordinator role.<br />

** Part-time unit manager who is also one of the study nurses.<br />

The unit uses laboratory <strong>and</strong> pharmacy staff outside Vancouver General Hospital in its conduct of clinical<br />

trials.<br />

Quality control/assurance procedures are based on extensive St<strong>and</strong>ard Operating Procedures which<br />

are read <strong>and</strong> signed by all staff <strong>and</strong> updated as required (minimum annually). Furthermore, all investigators/staff<br />

have completed the “NCI Human Participant Protections Education for Research Teams online<br />

course”, have read the “GCP Guidelines”, <strong>and</strong> have a Certificate of Completion of the “NCIC CTG Certificate<br />

on GCP Guidelines”. All projects are approved by the REB prior to initiation.<br />

Contact:<br />

Palmer, Maureen. R.N. Tel: 604-875-5675. maureen.palmer@vch.ca.<br />

IT<br />

Vancouver Retinal Research Group<br />

Based at the VGH/ UBC Eye Care Centre, the Vancouver Retinal Research Group conducts Phases II <strong>and</strong><br />

III clinical trials, as well as investigator initiated <strong>and</strong> grant funded studies into macular degeneration,<br />

diabetic retinopathy, <strong>and</strong> central retina vein occlusion. It offers study design, protocol preparation,<br />

budget preparation, ethics applications, source documents, <strong>and</strong> study facilitation (i.e., coordinates study<br />

procedure with various departments <strong>and</strong> investigators, study staff training, <strong>and</strong> oversight). It has no<br />

independent URL.


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The Research Group consists of three investigators, whose details can be found in Appendix 6:<br />

• Albiani, David<br />

• Merkur, Andrew<br />

• Potter, Michael<br />

Staffing of the unit is as follows:<br />

Study Nurses 1<br />

Research Assistants<br />

3<br />

Data Managers/<br />

Coordinators<br />

Pharmacy Staff Laboratory Staff Other<br />

1 2 1* 0 0 2 **<br />

* This role is occupied by a part-time Research Assistant/Scientist who conducts data mining <strong>and</strong> statistical analysis.<br />

** Vision examiner, treatment assistant.<br />

The unit uses pharmacy staff at <strong>and</strong> outside Vancouver General Hospital in its conduct of clinical trials. It<br />

also uses external laboratory staff.<br />

Quality control/assurance procedures are mainly based on Eye Care Centre st<strong>and</strong>ard practice guidelines,<br />

as well as St<strong>and</strong>ard Operating Procedures. The latter are site specific for the Informed Consent<br />

Form process <strong>and</strong> sponsor specific for each study, including drug accountability <strong>and</strong> drug destruction.<br />

All studies are conducted according to ICH Guidelines. Staff <strong>and</strong> investigators are trained by sponsors,<br />

via a clinical trials specific CDROM, <strong>and</strong> at relevant meetings. All staff are encouraged to obtain SOCRA<br />

(Society of <strong>Clinical</strong> Research Associates) certification. All projects are approved by the REB prior to initiation.<br />

Contact:<br />

Gillies, Dawne RN. <strong>Clinical</strong> Research Coordinator. Tel: 604-875-4253. dawne.gillies@vch.ca.<br />

UBC Hospital<br />

Alzheimer Disease & Related Disorders’ Clinic<br />

The Alzheimer Disease & Related Disorders’ Clinic is located at UBC Hospital (http://ubc-alzclinic.vch.ca/<br />

index.html). The clinic sees over 1,200 patients a year 5 . It is active in Phases II <strong>and</strong> III clinical trials.<br />

The Medical Director (Feldman, Howard) <strong>and</strong> five collaborating physicians take part in clinical trials. The<br />

clinic also has a research coordinator, research assistant, <strong>and</strong> statistician. <strong>Trials</strong> include trying to delay<br />

disease progression in patients with mild cognitive impairment, the treatment of patients with mild to<br />

moderate Alzheimer’s disease, <strong>and</strong> the use of neuroimaging.<br />

Contact:<br />

O’Neill, Valarie. Senior <strong>Clinical</strong> Research Coordinator. Tel: 604-822-7990.<br />

Bladder Care Centre<br />

The Bladder Care Centre (BCC) is an integrated multidisciplinary diagnostic, treatment <strong>and</strong> research<br />

facility for bladder symptoms located at UBC Hospital (http://urology.ubc.ca/bladder-care-centre).<br />

Working at the centre are physicians, surgeons, nurses <strong>and</strong> physiotherapists who are specialized in the<br />

diagnosis <strong>and</strong> treatment of lower urinary tract symptoms. The BCC links patients, clients, health professionals<br />

<strong>and</strong> researchers to study <strong>and</strong> advance the goals of prevention <strong>and</strong> treatment of lower urinary


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

85<br />

tract symptoms in both men <strong>and</strong> women. <strong>Clinical</strong> studies in patients include the investigation of medicines<br />

as well as naturopathic <strong>and</strong> complementary therapies.<br />

Contact:<br />

Stothers, Lynn. Director of Research. Tel: 604-822-7616. lynns@interchange.ubc.ca. See Appendix 6 for<br />

her details.<br />

Mood Disorders Centre of Excellence UBC: <strong>Clinical</strong> <strong>Trials</strong> Section<br />

Based at UBC Hospital, the UBC Mood Disorders Centre of Excellence (CoE) (www.ubcmood.ca) develops,<br />

evaluates <strong>and</strong> provides innovative programs of care, educating health professionals <strong>and</strong> the public,<br />

<strong>and</strong> conducting clinical studies on the causes of, <strong>and</strong> treatments for, mood disorders (particularly depression<br />

<strong>and</strong> bipolar disorders). It is affiliated with the Department of Psychiatry, UBC; Vancouver Coastal<br />

Health Research Institute; <strong>and</strong> the UBC Institute of Mental Health. It sees approximately 470 new patients<br />

per year, of which 20% may be enrolled into studies. It serves both in-patients <strong>and</strong> out-patients.<br />

The CoE has 16 investigators, as listed below <strong>and</strong> detailed in Appendix 6. It conducts Phases I – IV clinical<br />

trials, as well as investigator-initiated <strong>and</strong> grant-funded studies.<br />

• Andreazza, Ana<br />

• Michalak, Erin<br />

• Axler, Auby<br />

• Tam, Edwin<br />

• Bond, David<br />

• Torres, Ivan<br />

• Gigante, Alex<strong>and</strong>re<br />

• Vik, Astrid<br />

• Hadjipavlou, George<br />

• Wiese, Bonnie<br />

• Kunz, Mauricio<br />

• Yatham, Lakshmi<br />

• Lam, Raymond (Medical Director) • Young, Allan<br />

• Lau, Mark<br />

• Young, Trevor<br />

Staffing of the Centre is as follows:<br />

Study Nurses/<br />

Coordinators 1<br />

Research Assistants<br />

3<br />

Data Managers/<br />

Coordinators<br />

Pharmacy/ Lab<br />

Staff<br />

Admin<br />

6 2 (part-time) 0 0 0 1*<br />

* Data entry clerk – casual position<br />

It uses both UBC Hospital <strong>and</strong> external pharmacy <strong>and</strong> laboratory facilities in the conduct of its clinical<br />

trials.<br />

Quality control <strong>and</strong> assurance are procedures are based on SOPs <strong>and</strong> the Good <strong>Clinical</strong> Practice guidelines<br />

of the FDA/Health Canada. The division provides regular training sessions for researchers <strong>and</strong><br />

staff members in the conduct of clinical studies <strong>and</strong> GCP regulations <strong>and</strong> guidelines. New staff are also<br />

trained in REB procedures, hospital research guidelines, Health Canada Tri-Council Policy Statement,<br />

psychological assessment scales, ECG, <strong>and</strong> dangerous goods.<br />

Contact:<br />

Woo, Cindy. Research Coordinator. Tel: 604 822 7627. cinw@interchange.ubc.ca.<br />

Other<br />

5<br />

Neuroscience <strong>Asset</strong> <strong>Map</strong>: Activities, Strengths And Opportunities. Published 2007. www.investbc.com/assetmaps.htm. Accessed January 28,<br />

2010.


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Multiple Sclerosis Clinic<br />

The Multiple Sclerosis Clinic (www.ubcneurology.com/Research_MS.html) operates at UBC Hospital.<br />

It had 3,698 patient visits <strong>and</strong> 635 new patients in 2007. The clinic coordinates new escalating therapy<br />

options for aggressive MS <strong>and</strong> also provides specialized care for neuromyelitis optica (NMO). It provides<br />

outreach support to clinics in Victoria (1,000 patients registered), Kelowna (700 patients), <strong>and</strong> Prince<br />

George (300 patients), as well as providing outreach care directly to patients in Comox (Vancouver<br />

Isl<strong>and</strong>).<br />

Therapeutic trials in MS have encompassed both disease modifying <strong>and</strong> symptomatic therapies. All<br />

stages <strong>and</strong> types of MS have been represented in at least Phases II <strong>and</strong> III trials. Investigators have a<br />

strong profile in clinical trial development, safety monitoring <strong>and</strong> MRI/immunology sub-studies. The<br />

MS/MRI Research Group has provided central analysis for numerous international multicentre r<strong>and</strong>omized<br />

clinical trials <strong>and</strong> are recognized internationally for their work in this area.<br />

The Clinic’s seven neurologist investigators are as follows, with details contained in Appendix 6:<br />

• Devonshire, Virginia • Oger, Joel<br />

• Hashimoto, Stanley • Rieckmann, Peter<br />

• Hooge, John<br />

• Traboulsee, Anthony<br />

• Kastrukoff, Lorne<br />

Contact:<br />

Traboulsee, A. Head of <strong>Clinical</strong> <strong>Trials</strong> Group. Tel: 604 822-0788. trabouls@interchange.ubc.ca.<br />

Pacific Parkinson’s Research Centre<br />

Located at UBC Hospital, the Pacific Parkinson’s Research Centre is a multidisciplinary program dedicated<br />

to the diagnosis <strong>and</strong> management of Parkinson’s <strong>and</strong> other related disorders, such as tremor <strong>and</strong><br />

dystonia (www.parkinsons.ubc.ca/index.html). It has been designated as a Centre of Excellence by the<br />

National Parkinson Foundation in the US. In addition to treating patients, it has a strong research program<br />

that spans preclinical, clinical <strong>and</strong> population studies. Under the direction of Dr. Jonathan Stoessl,<br />

an internationally recognized expert on Parkinson’s disease, the centre has the largest peer-reviewed<br />

research program in Canada on Parkinson’s disease.<br />

The Centre has three neurologists (listed below), whose details can be found in Appendix 6.<br />

• McKeown, Martin J.<br />

• Stoessl, Jonathan<br />

• Tsui, Joseph<br />

These investigators conduct trials involving novel drugs, surgery, <strong>and</strong> neuroimaging. Patients registered<br />

with the UBC Movement Disorders Clinic in 2007 included 1,100 with typical Parkinson’s disease, 400<br />

patients with Parkinson-like disorders, <strong>and</strong> 500 – 1,000 with dystonia 5 .<br />

The Centre also has a clinical trials coordinator. It conducts Phases I, II, III, <strong>and</strong> IV studies.<br />

Contact:<br />

Babul, Shamin. Administrator. Tel: 604-822-7721. ndsb@interchange.ubc.ca.


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87<br />

University of British Columbia Medical Departments Supporting B.C. Hospitals<br />

Anesthesia Department<br />

The Anesthesia Department supports anesthesiologists at VGH, St. Paul’s, B.C. Women’s, B.C. Children’s,<br />

<strong>and</strong> Royal Columbian Hospitals (www.anesthesia.med.ubc.ca/cfmx/anesthesia/RCH/aboutus.cfm). The<br />

clinical trials groups at VGH <strong>and</strong> St. Paul’s are very active in studying acute pain.<br />

Investigators include the following whose details are contained in Appendix 6:<br />

• Choi, Peter (VGH)<br />

• Puil, Ernie<br />

• Cole, Colm (St. Paul’s)<br />

• Warriner, Brian (VGH)<br />

• Merchant, Richard (Royal Columbian)<br />

Contact:<br />

Cole, Colm. Head of Anesthesia, St. Paul’s Hospital. Tel: 604 806-8337. cole@providencehealth.bc.ca.<br />

Choi, Peter. Director of <strong>Clinical</strong> Research. Tel: 604 875-4111 x 68433. petert.choi@vch.ca.<br />

Critical Care Medicine<br />

The Division of Critical Care Medicine supports clinical trials at VGH, St Paul’s, B.C. Children’s Hospital,<br />

Richmond General, Nanaimo Regional General, Royal Columbian, <strong>and</strong> Surrey Memorial Hospitals (www.<br />

ubccriticalcaremedicine.ca). A description of the Critical Care clinical trials conducted at Royal Columbian<br />

<strong>and</strong> Surrey Memorial Hospitals (Fraser Health Authority) can be found above. Principal Investigators<br />

include the following, whose details can be found in Appendix 6:<br />

• Ayas, Najib<br />

• Fenwick, John<br />

• Chittock, Dean • Henderson, William<br />

• Dhingra, Vinay • Reynolds, Steven<br />

• Dodek, Peter<br />

• Ronco, Juan<br />

• Dorscheid, Delbert • Russell, James<br />

They conduct clinical trials in apnea, sepsis <strong>and</strong> septic shock, prevention of thromboembolism, ARDS<br />

<strong>and</strong> other inflammatory lung diseases, <strong>and</strong> traumatic brain injury.<br />

Contact:<br />

Dhingra, Vinay. Tel: 604 875-5949. vinay.dhingra@vch.ca.<br />

Endocrinology <strong>and</strong> Metabolism<br />

The Division of Endocrinology <strong>and</strong> Metabolism supports clinical trials at both VGH <strong>and</strong> St Paul’s Hospitals<br />

(no URL). Principal Investigators include the following, whose details can be found in Appendix 6:<br />

• Elliott, Tom<br />

• Ur, Ehud<br />

• Sirrs, S<strong>and</strong>ra<br />

<strong>Clinical</strong> trials include those on neuroendocrine disorders, diabetes, dyslipidemia, <strong>and</strong> obesity.<br />

Contact:<br />

Ur, Ehud. Division Head. Tel: 604 875-4552. ehud.ur@vch.ca.


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Gastroenterology<br />

The Division of Gastroenterology supports clinical trials at both VGH <strong>and</strong> St Paul’s Hospitals (no URL).<br />

Principal Investigators include the following, whose details can be found in Appendix 6:<br />

• Anderson, Frank • Gray, James<br />

• Byrne, Michael • Weiss, Alan<br />

• Enns, Rob<br />

• Yoshida, Eric<br />

They conduct clinical trials in colitis, Crohn’s, liver disease (e.g., hepatitis, cancer), GERD <strong>and</strong> erosive<br />

esophagitis, motility, <strong>and</strong> other areas of gastrointestinal disease.<br />

Contact:<br />

Byrne, Michael. Tel: 604 875-5640. michael.byrne@vch.ca.<br />

Obstetrics <strong>and</strong> Gynecology Department<br />

The Department of Obstetrics <strong>and</strong> Gynecology (www.obstgyn.ca) supports its faculty that are involved<br />

clinical research in many B.C. hospitals, including B.C. Women’s Hospital, Vancouver General Hospital, St.<br />

Paul’s Hospital, <strong>and</strong> Royal Columbian Hospital. They work with the infrastructure provided by hospital<br />

<strong>and</strong> health authority based resources.<br />

Investigators include the following whose details can be found in Appendix 6:<br />

B.C. Women’s Hospital<br />

VGH<br />

• Butler, Blair<br />

• Brotto, Lori<br />

• Cheung, Anthony<br />

• Kwon, Janice<br />

• Delisle, Marie France<br />

• Miller, Dianne<br />

• Gagnon, Alain<br />

• S<strong>and</strong>ers, Barry<br />

• Lim, Ken<br />

• Magee, Laura<br />

St Paul’s<br />

• Marquette, Gerry<br />

• Cundiff, Geoff<br />

• Mayer, Chantal<br />

• Geoffrion, Roxanna<br />

• Money, Deborah<br />

• Skoll, Am<strong>and</strong>a<br />

Royal Columbian<br />

• von Dadelszen, Peter<br />

• Sorokan, Todd<br />

Contact:<br />

Fern<strong>and</strong>ez, Ariadne. Research Program Manager. afern<strong>and</strong>ez@phsa.ca.


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APPENDIX 2.<br />

DESCRIPTION OF B.C.’S CLINICAL TRIALS SUPPORT UNITS<br />

Providence Health Care Society<br />

Providence Health Care Research Institute (PHCRI) <strong>and</strong> the Centre for Health Evaluation <strong>and</strong><br />

Outcome <strong>Sciences</strong> (CHEOS)<br />

The Providence Health Care Research Institute (PHCRI) <strong>and</strong> the Centre for Health Evaluation <strong>and</strong> Outcome<br />

<strong>Sciences</strong> (CHEOS) (www.cheos.ubc.ca), the clinical research centre of PHCRI, work together to<br />

provide support for investigators conducting clinical research. PHCRI provides the following administrative<br />

services through the Office of Research Services [12 employees]:<br />

• Research Ethics Board review<br />

• Contract Negotiation<br />

• Human Resource Management of PHCRI employees<br />

• Financial administration.<br />

CHEOS is an interdisciplinary research collective of 45+ investigators <strong>and</strong> houses a <strong>Clinical</strong> <strong>Trials</strong> Support<br />

Unit (CTSU) to facilitate <strong>and</strong> assist Providence Health Care clinical investigators with the development<br />

<strong>and</strong> management of clinical trials. Services include:<br />

• Study design <strong>and</strong> methodology<br />

• Statistical analysis<br />

• Budget planning<br />

• Study logistics<br />

• Health economic analysis<br />

• Data form creation (paper or electronic)<br />

• Database development<br />

• Data entry/validation<br />

• Training including clinical research regulations, investigator’s meetings <strong>and</strong> study procedures for<br />

clinical site personnel<br />

• Study document creation including informed consent form templates, st<strong>and</strong>ard operating procedures,<br />

study manuals, <strong>and</strong> participant advertising<br />

• Regulatory process <strong>and</strong> documentation<br />

• Project management assessment<br />

• Study registration<br />

• Assistance with knowledge translation<br />

The CTSU conducts Phases II through IV clinical trials. Forty-five researchers who conduct clinical trials<br />

are affiliated with CHEOS, including those listed in Table A1. Details about those investigators who conduct<br />

clinical trials can be found in Appendix 6. CHEOS’ structure is shown in Figure A9.<br />

The staff working on CHEOS projects is as follows (total = 66):<br />

<strong>Clinical</strong><br />

Project<br />

Managers<br />

Study Coordinators<br />

Data Managers<br />

Information<br />

Management*<br />

Statisticians Data Entry Health<br />

Economists<br />

Admin.<br />

5 12 6 16 10 2 7 8<br />

* For example: database administrators, programmers.


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Since the Centre is located in St. Paul’s Hospital, the hospital pharmacy <strong>and</strong> laboratory are used for research studies.<br />

TABLE A1. Providence Health Care Society Program-affiliated Research Coordinators <strong>and</strong> Researchers<br />

Department Program Researchers Managers/Coordinators<br />

Medicine Critical Care Research Dr. Peter Dodek<br />

Dr. John Boyd<br />

Dr Ruth MacRedmond<br />

Dr. Adam Peets<br />

Dr. Najib Ayas<br />

Dr. Keith Walley<br />

Dr. Jim Russell<br />

Dr. Delbert Dorscheid<br />

Dr. Demetrious Sirounis<br />

Medicine<br />

(Immunology/<br />

Respirology)<br />

Medicine<br />

(Immunology/<br />

Respirology)<br />

James Hogg iCAPTURE Centre<br />

(heart, blood vessel <strong>and</strong> lung diseases)<br />

Pacific Lung Health Centre<br />

(respiratory diseases)<br />

Dr. Robert Schellenberg<br />

Dr. Tony Bai<br />

Dr. Bruce McManus<br />

Dr. Delbert Dorscheid<br />

Dr. Peter Pare<br />

Dr. Jiri Frohlich<br />

Dr. James Russell<br />

Dr. John Hill<br />

Dr. James Hogg<br />

Dr. Don Sin<br />

Dr. Darryl Knight<br />

Dr. Stephan van Eeden<br />

Dr. Paul Man<br />

Dr. Tony Bai<br />

Dr. Robert Schellenberg<br />

Dr. Lindsay Lawson<br />

Dr. Robert Levy<br />

Dr. Don Sin<br />

Dr. Stephan van Eeden<br />

Dr. Paul Man<br />

Dr. Wan-Cheng Tan<br />

Dr. Barbara Nakielna<br />

Dr. Pearce Wilcox<br />

Dr. Peter Pare<br />

Betty Jean Ashley<br />

Lynda Lazosky<br />

Roxanne Rousseau<br />

Mark Elliot<br />

Jane Burns<br />

Leslie Love – Research Manager<br />

Salima Lakhpati<br />

Rayna Sivakova<br />

Wen Wang


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Department Program Researchers Managers/Coordinators<br />

Medicine Hematology Research Dr. Heather Leitch<br />

Dr. Linda Vickars<br />

Medicine<br />

(Infectious Disease)<br />

Centre for Excellence in HIV/AIDS;<br />

Canadian HIV <strong>Trials</strong> Network<br />

Dr. Julio Montaner<br />

Dr. Rol<strong>and</strong>o Barrios<br />

Dr. Silvia Guillemi<br />

Dr. Peter Phillips<br />

Dr. Peter Phillips<br />

Dr. Marianne Harris<br />

Dr. Val Montessori<br />

Dr. Natasha Press<br />

Medicine Nephrology Research Dr. Adeera Levin<br />

Dr. Jag Gill<br />

Dr. David L<strong>and</strong>sberg<br />

Dr. Monica Baeulieu<br />

Dr. Paul Taylor<br />

Dr. Anthony Chiu<br />

Marketa Waldrum – Research Manager<br />

Mahi Etminam<br />

Evani Goll<br />

Adam Ludlow<br />

Gerene Larson<br />

Paula Ochoa<br />

Andy Mtambo<br />

William Chau<br />

Katy Vela – Research Manger<br />

S<strong>and</strong>ra Matzek, Lina Sioson, Mila Tang, Nancy<br />

Ferguson, Deborah Kraus, Sheila O’Donoghue,<br />

Anna Chala, Elizabeth Hendren, Patrich Altejos,<br />

James Dong, Caren Rose, Mohua Podder,<br />

Martin Kwiatkowski, Sara Assadian, Breanne<br />

Crouch


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TABLE A1. Providence Health Care Society Program-affiliated Research Coordinators <strong>and</strong> Researchers (cont’d)<br />

Department Program Researchers Managers/Coordinators<br />

Medicine/ Surgery<br />

(Cardiology)<br />

The Healthy Heart Program;<br />

Interventional Cardiology;<br />

Atrial Fibrillation/ Arrythmia Device<br />

Cardiovascular Surgery Research<br />

Surgery Colorectal Research<br />

Heart Failure <strong>and</strong> Acute Coronary Research<br />

Dr. Jiri Frohlich<br />

Dr. Chris Thompson<br />

Dr. James Abel<br />

Dr. Jaap Hamburger<br />

Dr. S<strong>and</strong>ra Sirrs<br />

Dr. Anson Cheung<br />

Dr. Andy Ignaszewski<br />

Dr. Lynn Straatman<br />

Dr. Eve Aymong<br />

Dr. Charles Kerr<br />

Dr. Stanley Tung<br />

Dr. Greg Bondy<br />

Dr. Samual Lichtenstein<br />

Dr. Ehud Ur<br />

Dr. John Bowering<br />

Dr. John Mancini<br />

Dr. John Webb<br />

Dr. Ron Carere<br />

Dr. Robert Moss<br />

Dr. Jian Ye<br />

Dr. Sammy Chan<br />

Dr. Simon Rabkin<br />

Dr. John Yeung<br />

Dr. Francis Gordon<br />

Dr. Krishnan Ramanathan<br />

Dr. Anthony Fung<br />

Dr. Donald Ricci<br />

Dr. S Chackrabarti<br />

Dr. Terry Phang<br />

Carol Honeyman – Research Manger (Atrial<br />

Fibrillation/ Arrhythmic Device)<br />

Elizabeth Grieve –Research Manager (Interventional<br />

Cardiology)<br />

Gail Vincente – Research Manager (Cardiovascular<br />

Surgery)<br />

Kevin Shillitto<br />

Sarah Shepherd<br />

Debbie De Angelis<br />

Petra Hajek<br />

Tanja Kot<br />

Leuka Miklosova<br />

Satvir Mirhas<br />

Parveen Sangha<br />

Esther Zwanenberg<br />

TStella Yeung<br />

Foot <strong>and</strong> Ankle Clinic Orthopedics Research<br />

Group<br />

Dr. Alastair Younger<br />

Dr. Tung ChuoYang<br />

Dr. Donna Smith<br />

Biraj Bora – Research Manager (Foot <strong>and</strong> Ankle<br />

Orthopedics)


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Department Program Researchers Managers/Coordinators<br />

Obstetrics <strong>and</strong> Gynacology Dr. Geoff Cundiff<br />

Dr. Rozana Geoffrion<br />

Dr. Rob Anderson<br />

Theresa Young<br />

Anesthesiology Dr. Stephen Swartz<br />

Dr. Moore<br />

Emergency Emergency Medicine Research Dr. Rob Stenstrom<br />

Dr. Eric Grafstein<br />

Dr. Devin Harris<br />

Dr. Garth Hunte<br />

Dr. Frank Scheuermeyer Dr. Jim Christenson<br />

Traci Corr<br />

Parveen Sangha<br />

Iraj Poureslami (Research Manager – Emergency<br />

Department)<br />

Barb Boychuk (NIH Research)


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FIGURE A9. Centre for Health Evaluation <strong>and</strong> Outcome <strong>Sciences</strong><br />

Dr. Yvonne Lefebrve<br />

Vice President, Research & Academic Affairs<br />

Providence Health Care Research Institute<br />

Dr. Aslam Anis<br />

Director, CHÉOS<br />

Professor, School of Population & Public Health UBC<br />

John Orr<br />

Director of Operations<br />

Joel Singer/Hubert Wong<br />

Co-Department Heads, Statistics,<br />

Data & Methodology<br />

Erin Cherban<br />

Manager, <strong>Clinical</strong> Trial Support<br />

Unit<br />

Research Administrative<br />

Coordinator & Bookkeeper<br />

Statisticians, Data Managers<br />

Database Developers, IT,<br />

Programmers, Data Entry<br />

Health Economist<br />

<strong>Clinical</strong> Research Project<br />

Managers<br />

PHC Ethics Submission<br />

Coordinator<br />

The process for getting trials approved by the unit is as follows. Investigators from Providence Health<br />

Care contact CHEOS to request services. The requests are then evaluated by the appropriate departments,<br />

for example, the Director of Operations, the Department Head of Statistics <strong>and</strong> Methodology,<br />

or the Manager of the <strong>Clinical</strong> Trial Support Unit. Once approved, CHEOS assists with the requested<br />

service, for example study start-up, database design, data management <strong>and</strong> statistical analysis for the<br />

entire study.<br />

Quality control/ assurance procedures are based on St<strong>and</strong>ard Operating Procedures compliant with<br />

Good <strong>Clinical</strong> Practice (GCP) guidelines. The unit also trains clinical trial personnel in clinical research<br />

procedures <strong>and</strong> GCP, <strong>and</strong> monitors local investigator-initiated clinical trials. CHEOS is a participant in the<br />

<strong>Clinical</strong> Research Professional Development (CRPD) team which has a curriculum of clinical research<br />

education for Lower Mainl<strong>and</strong> health centres. All projects are approved by the REB prior to initiation.<br />

Contact:<br />

Orr, John. Director of Operations. Tel: 604-806-2294. johnorr@mail.cheos.ubc.ca.<br />

Provincial Health Services Authority<br />

Child <strong>and</strong> Family Research Institute (CFRI) <strong>Clinical</strong> Research Support Unit<br />

The Child & Family Research Institute (CFRI) is dedicated to world-class research spanning a wide range<br />

of children’s <strong>and</strong> women’s health concerns. The Institute, based at B.C. Children’s Hospital, provides support<br />

for investigators conducting clinical research through its Administration <strong>and</strong> the <strong>Clinical</strong> Research<br />

Support Unit (CRSU) (www.cfri.ca/research_support/clinical_research_support/default.asp). The CRSU<br />

staff <strong>and</strong> faculty have expertise in epidemiology, statistics <strong>and</strong> economics, <strong>and</strong> provide support to clinician<br />

investigators including research project <strong>and</strong> program development, study design, data collection<br />

<strong>and</strong> management, <strong>and</strong> statistical analysis. A trials data management system includes a r<strong>and</strong>omization<br />

module <strong>and</strong> ability to import images.


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Among other services, the CRSU offers the following. Staffing is indicated in parentheses.<br />

• Methodology <strong>and</strong> Biostatistics Services, including research project development, study design <strong>and</strong><br />

methodology, statistical analysis <strong>and</strong> data management (www.cfri.ca/crs/Biostatistics.asp) [3 staff; 4<br />

faculty]<br />

• Data Management services that meet Health Canada <strong>and</strong> FDA requirements. CFRI investigators<br />

have access to a trials data management software platform, assistance in the design of forms <strong>and</strong><br />

reports, <strong>and</strong> training of data entry staff. Data storage is managed on a secure platform by CFRI IT<br />

Services. This service supports about 1,000 studies a year [2 programmers, 1 trainer/form developer,<br />

1 regulatory affairs manager to support SOP development]<br />

• Facilities including the B.C. Children’s Hospital Chieng Medical Day Unit, offering support for clinical<br />

trials requiring nursing care <strong>and</strong> monitoring during interventions; <strong>and</strong> the <strong>Clinical</strong> Research <strong>and</strong><br />

Evaluation Unit for minimally invasive studies, providing eight exam rooms, wet <strong>and</strong> dry storage<br />

rooms, <strong>and</strong> a staff study-coordination room (www.cfri.ca/crs/researchclinic.asp)<br />

• Hospital Services Research Coordinators are in place to support individual research studies <strong>and</strong><br />

liaise with investigators <strong>and</strong> others as required during studies, in Laboratory Services (www.cfri.ca/<br />

crs/laboratoryservices.asp); Pharmacy Services to support research studies (www.cfri.ca/crs/pharmacy);<br />

Perinatal Services (patient recruitment <strong>and</strong> samples management); <strong>and</strong> Health Records (for<br />

chart retrieval, abstracting <strong>and</strong> audit purposes). [4 staff in total].<br />

In addition to the Hospital Services Research Coordinators mentioned above, there are a large number<br />

of research program coordinators, the senior members of which are listed in Table A2.<br />

FIGURE A10. Structure of CFRI<br />

PHSA<br />

Board of Directors<br />

Chair, Donald Brooks<br />

UBC<br />

Executive Director<br />

Stuart MacLeod<br />

<strong>Clinical</strong><br />

Research<br />

Support<br />

Director <strong>Clinical</strong> &<br />

Population Health<br />

Anne Junker<br />

Scientific Director<br />

Geoff Hammond<br />

Human Resources<br />

Advisor<br />

Tracie Galbraith<br />

Director,<br />

Communications<br />

Jennifer Kohm<br />

Director, Finance<br />

Anita Chiu<br />

Director, Research &<br />

Education Services<br />

Allison Rintoul<br />

Senior Research<br />

Development Facilitator<br />

Dawn MacArthur<br />

Manager, Facilities &<br />

Operations<br />

Todd Jacques<br />

Manager, IM/IT<br />

Gurm Dhugga<br />

Communications<br />

Specialist<br />

Web Developer*<br />

Finance Managers<br />

Finance Assistants<br />

Contracts Coordinator<br />

Research Legal Counsel<br />

Project Associate<br />

Manager, Res Education<br />

Assistant, Res Ed<br />

Initiatives<br />

Assistant, Inst Initiatives<br />

Assistant, Faculty<br />

Initiatives<br />

Assistant, Reading Room<br />

Manager, REB<br />

Manager, Pre/Post<br />

Review<br />

Admin Coordinator, REB<br />

Research Development<br />

Facilitator<br />

Proposal Coordinator(s)<br />

Grants Assistant(s)<br />

Technology Transfer<br />

Manager (UILO)<br />

Facilities Coordinator<br />

Facilities Assistant<br />

Animal Unit Senior Tech<br />

Tech(s) Level 3<br />

Lab Asst Level 1<br />

Systems Analyst<br />

System Tech<br />

Web Developer*


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The Unit supports all Phases of therapeutic <strong>and</strong> device clinical trials, as well as behavioural, investigatorinitiated<br />

<strong>and</strong> grant funded studies. The structure of the CRSU within CFRI is shown in Figure A10.<br />

CFRI itself is structured into research pillars <strong>and</strong> disease clusters, with numerous investigators working in<br />

all aspects of clinical research (not just clinical trials) as indicated in Table A2. Details about the investigators<br />

who conduct clinical trials can be found in Appendix 6.


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TABLE A2. CFRI Program-affiliated Research Coordinators <strong>and</strong> Researchers<br />

CFRI Cluster GI Terry Viczko, Research Coordinator Researchers<br />

Genetics <strong>and</strong> Health <strong>Clinical</strong> Genetics Marion Thomas, Research Manager Dr. Cornelius Boerkoel<br />

Dr. Millan Patel<br />

Dr. Jan Friedman<br />

iACT - Acute <strong>and</strong> Critical Care <strong>and</strong> Technologies Anesthesia Joanne Lim, Research Manager Dr. Mark Ansermino<br />

Dr. Carolyn Montgomery<br />

Immunity in Health <strong>and</strong> Disease (Infectious<br />

Disease, Inflammation, Immunity)<br />

Cardiac Jim Potts, <strong>Clinical</strong> Epidemiologist Dr. Derek Human<br />

Dr. George S<strong>and</strong>or<br />

Dr. Martin Hosking<br />

Dr. Jacques Leblanc<br />

Dr. Andrew Campbell<br />

Karen Gibbs, Electrophysiology Research Manager Dr. Shubhayan Sanatani<br />

Emergency Anne Marie White, Research Coordinator Dr. Quynh Doan<br />

Dr. Ran Goldman<br />

Dr. Adam Cheng<br />

Dr. Geoffrey Hung<br />

Plastic Surgery Angie Perdios, Research Manager Dr. Cynthia Verchere<br />

Dr. Douglas Courtemanche<br />

Dr. Jugpal Arneja<br />

Orthopedics Katie Fukushima, Research Manager Dr. Christopher Reilly<br />

Dr. Firoz Miyanji<br />

Dr. Kishore Mulpuri<br />

Dr. Richard Beauchamp<br />

PICU Gordon Krahn, Research <strong>and</strong> Quality Initiatives<br />

Coordinator<br />

Dr. Peter Skippen<br />

Dr. David Wensley Surgery<br />

Surgery Damian Duffy, Executive Director, OPSEI Dr. Erik Skarsgard<br />

Dr. Geoffrey Blair<br />

Renal Josephine Chow, Research Coordinator Dr. Douglas Matsell<br />

Dr. Colin White<br />

Dr. Mina Matsuda-Abedini<br />

Allergy Terry Viczko, Research Coordinator Dr. Edmond Chan<br />

Dr. Mark Chilvers (Resp)<br />

CHILD Roxanne Rousseau, Research Coordinator Dr. Stuart Turvey (CHILD,MiniCHILD)<br />

Dr. Edmond Chan (CAPPS)<br />

Dr. Tobi Kollmann (CB Study)<br />

Dermatology Terry Viczko, Research Coordinator Dr. Prendiville


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TABLE A2. CFRI Program-affiliated Research Coordinators <strong>and</strong> Researchers (cont’d)<br />

CFRI Cluster GI Terry Viczko, Research Coordinator Researchers<br />

Developmental Neurosciences & Child Health: Neurons<br />

to Neighbourhoods (N2N)<br />

GI Terry Viczko, Research Coordinator Dr. Kevan Jacobson<br />

Dr. Rick Schreiber<br />

Immunity/Infectious Disease Maureen Campbell, Research Manager Dr. David Speert<br />

Dr. Stuart Turvey<br />

Dr. Rusang Tan<br />

Oak Tree HIV Evelyn Maan, Research Manager Dr. Jack Forbes<br />

Dr. David Burdge<br />

Dr. Deborah Money<br />

Dr. Arianne Alimenti<br />

Rheumatology America Uribe, Research Manager Dr. Lori Tucker<br />

Dr. David Cabral<br />

Dr. Kristin Houghton<br />

Dr. Jaime Guzman<br />

VEC - Vaccine Evaluation Centre Arlene Kallos, <strong>Clinical</strong> Trial Unit Manager Dr. David Scheifele<br />

Dr. Simon Dobson<br />

B.C. Injury Research & Prevention<br />

Unit<br />

CYDiS (Children & Youth w/<br />

Disabilities in Society)<br />

Carol LaJeunesse, <strong>Clinical</strong> Trial Unit Manager<br />

Shannon Piedt, Project Coordinator Dr. Ian Pike<br />

Dr. Mariana Brussoni<br />

Jane Shen, Research Manager Dr. Anton Miller<br />

Dr. Maureen O’Donnell<br />

Developmental Neuroscience Vesna Popovska, Research Manager Dr. Steven Miller<br />

Dr. Connolly<br />

Dr. Steinbok<br />

Dr. Farrell<br />

Biochemical Diseases Terry Viczko, Research Coordinator Dr. George Davidson<br />

Dr. Louise Mâsse Maria Valente, Research Coordinator Dr. Louise Mâsse<br />

Dr. Rollin Brant<br />

Maternity Care Research Group Jocelyn Tomkinson, Research Manager Dr. Michael C. Klein<br />

Dr. Janusz Kaczorowski<br />

Dr. Rob Liston<br />

Early Human Experience Unit<br />

Learning & Development Ivan Cepeda, Research Manager Dr. Ruth E. Grunau<br />

Developmental Care Program Colleen Jantzen, Research Coordinator Dr. Lisa Holsti<br />

Child Development Program Ruth Wilson, N2N Administrative Manager Dr. Ron Barr (N2N Director)<br />

Healthy Starts Program Ursula Brain, Research Manager Dr. Tim Oberl<strong>and</strong>er


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CFRI Cluster GI Terry Viczko, Research Coordinator Researchers<br />

Pediatric Palliative Care Gail Andrews, <strong>Clinical</strong> Research Coordinator Dr. Hal Siden<br />

Optimized Environments for<br />

D. Fay Warnock<br />

Infants<br />

Adolescent Health Program Dr. Elizabeth Saewyc<br />

Diabetes, Nutrition, <strong>and</strong> Metabolism Cystic Fibrosis Terry Viczko Dr. Mark Chilvers (Respirology)<br />

Diabetes Pamela Lutley, <strong>Clinical</strong> Research Coordinator<br />

Alyssa Park, Project Coordinator (Metabolism)<br />

Dr. Rusung Tan<br />

Dr. Dina Panagiotopoulos<br />

Dr. Bruce Verchere<br />

Endocrine Dr. Dina Panagiotopoulos<br />

Dr. Jana-Lee Davidson<br />

Metabolism<br />

Obesity<br />

Nutrition Roger Dyer, Lab Manager Dr. Sheila Innis<br />

Childhood Cancer (Oncology) COG Nita Takeuchi Dr. Mason Bond<br />

Non-COG Colleen Fitzgerald Dr. Paul Rogers<br />

Reproduction <strong>and</strong> Healthy Pregnancy Maternal Fetal Medicine<br />

(MFM)<br />

Reprod Endocrinology &<br />

Infertility<br />

Ariadna Fern<strong>and</strong>ez, Research Manager Dr. Peter Von Dadelszen<br />

Dr. Blair Butler<br />

Dr. Ken Lim<br />

+8 others<br />

Dr. Anthony Cheung<br />

Dr. Catherine Allaire<br />

NICU - Neonatology Jennifer Claydon, Research Manager Dr. Pascal Lavoie<br />

Dr. Rebecca Sherlock<br />

Dr. Alfonso Solimano<br />

Neonatal Follow-Up Arsalan Butt, Follow-Up Program Data Manager Dr. Anne Synnes<br />

Population Health POPI Anne Smith, Program Manager Dr. Bruce Carleton


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Quality control/ assurance procedures are based on Health Canada <strong>and</strong> FDA regulations. The Unit recommends<br />

<strong>and</strong> makes available the N2 SOPs covering GCP, along with N2 GCP Training modules. SOPs<br />

cover the Data Management <strong>and</strong> IT platform. All projects are approved by the REB prior to initiation.<br />

CFRI is a participant in the <strong>Clinical</strong> Research Professional Development (CPRD) team which has a curriculum<br />

coordinated between the Lower Mainl<strong>and</strong> academic health centres, directed for research<br />

coordinators (see Appendix 5).<br />

Contact: Junker, Anne. Director, <strong>Clinical</strong> & Population Health Studies, CFRI. Tel: 604-875-3591. ajunker@<br />

cw.bc.ca.<br />

Laboratory-<strong>Clinical</strong> Studies Unit<br />

Based at the B.C. Centre for Disease Control, the Laboratory-<strong>Clinical</strong> Studies Unit (www.phsa.ca/bccdcpublichealthlab)<br />

is associated with the B.C. Public Health Microbiology & Reference Laboratory (the<br />

primary public health <strong>and</strong> reference diagnostic testing facility for the province). It provides laboratory<br />

support for clinical trials on new molecular microbiology laboratory tests <strong>and</strong> test procedures, particularly<br />

for HPV, HIV, <strong>and</strong> Hepatitis. Studies cover screening, diagnosis, treatment, observation, <strong>and</strong> intervention.<br />

For treatment studies, the Unit provides support to Phases II, III, <strong>and</strong> IV clinical trials. Annual<br />

patient accrual ranges between 200 -11,000 depending on the study.<br />

The Unit has two Principal Investigators <strong>and</strong> three clinical trials collaborators listed below. Their details<br />

can be found in Appendix 6.<br />

Principal Investigators<br />

Collaborators<br />

• Krajden, Mel<br />

• Coldman, Andy<br />

• Petric, Martin<br />

• Ogilvie, Gina<br />

• Rekart, Michael<br />

Unit staffing is as follows (Total = 5):<br />

Study Nurses<br />

Data Managers/<br />

Coordinators<br />

Pharmacy Staff Laboratory Staff Administration/ Support<br />

Staff*<br />

0 1 Not applicable 4 1 (business consultant)<br />

For trials to be approved by the unit, the investigator must complete a project approval form <strong>and</strong> attach<br />

the clinical trial protocol, ethics approval documents, <strong>and</strong> funding approval documents for review.<br />

Upon review, the CTU will provide a laboratory cost estimate which all parties must sign-off before final<br />

approval.<br />

Since many of the tests conducted are new procedures, QC/QA procedures are newly developed for<br />

each one as follows:<br />

• Firstly, receive training from Vendor/Manufacturer of the new product/procedure<br />

• Secondly, the CTU performs an in-house validation <strong>and</strong> comparison if applicable<br />

• Thirdly, SOPs <strong>and</strong> QC procedures are created by the CTU following the College of American Pathologists<br />

(CAP) guidelines<br />

• Finally, other staff at the BCCDC are trained in the test, SOPs, <strong>and</strong> QC procedures.


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101<br />

Contact:<br />

Krajden, Mel. Associate Director, Laboratory Services. Tel: 604-707-2421. mel.krajden@bccdc.ca.<br />

Mei, Wendy. <strong>Clinical</strong> <strong>Trials</strong> Coordinator. Tel: 604-707-2643. wendy.mei@bccdc.ca.<br />

Fraser Health Authority<br />

Fraser Health Research & Evaluation<br />

Fraser Health (www.fraserhealth.ca) is a publicly funded regional authority that oversees the provision<br />

of all publicly funded health services at its owned <strong>and</strong> operated acute <strong>and</strong> community sites. It provides<br />

a wide range of integrated health care services to more than 1.5 million people living in communities<br />

stretching from Burnaby to White Rock to Hope. Its health care services range from 12 acute care hospitals<br />

to community-based residential, home health, mental health, <strong>and</strong> public health services.<br />

The Department of Evaluation <strong>and</strong> Research Services (http://research.fraserhealth.ca/home/) aims<br />

to establish Fraser Health as a premier site for the conduct of clinical, health services, <strong>and</strong> population<br />

health research, such that new knowledge is created <strong>and</strong> translated into policy <strong>and</strong> practice to enable<br />

“best in health, best in health care” for patients, clients, <strong>and</strong> residents. The Department supports 15 full<strong>and</strong><br />

part-time personnel <strong>and</strong> two Michael Smith Foundation for Health Research (MSFHR) grant funded<br />

‘Research Team Planning Strategists’. It provides services across all Fraser Health sites.<br />

Over 2,300 physicians provide services in Fraser Health facilities. Physicians who wish to participate in<br />

clinical trials as a site investigator are not employees of Fraser Health, but must have privileges with<br />

Fraser Health. Physicians are only allowed to conduct research at hospital sites for which they have<br />

privileges. Both physicians <strong>and</strong> Fraser Health are a party to contracts with industry <strong>and</strong> academic sponsors.<br />

The Department of Evaluation <strong>and</strong> Research Services supports Phase II, III <strong>and</strong> IV therapeutic <strong>and</strong> device<br />

clinical trials, as well as behavioural, investigator-initiated <strong>and</strong> grant funded studies. Details about 50<br />

investigators who conduct clinical trials can be found in Appendix 6. The following types of services<br />

<strong>and</strong> support is listed below with staffing indicated in parentheses.<br />

• Health Research Intelligence Unit: Methodology <strong>and</strong> Biostatistics Services, including research<br />

project/protocol development, study design <strong>and</strong> methodology, budget development, statistical<br />

analysis, data management, <strong>and</strong> grant administration [Epidemiologist <strong>and</strong> Research/Grant Development<br />

Facilitator – 2 FTE]<br />

• Ethical Review: Assistance with REB submissions, education, <strong>and</strong> site monitoring oversight [Research<br />

Ethics Coordinator]<br />

• Research-related services provided by Research Coordinators, funded by individual FH departments,<br />

provide integrated support to individual research studies, co-ordinate all applicable approvals<br />

for the provision of service by their department, <strong>and</strong> liaise with investigators <strong>and</strong> others as<br />

required during studies: Laboratory Services [1 staff ]; Pharmacy Services [1 staff ]; Perinatal Services<br />

(patient recruitment <strong>and</strong> samples management); <strong>and</strong> Health Records [1 FTE].<br />

• Administration of clinical trials registration at clinicaltrials.gov<br />

• Contract Review: Contract negotiation conducted by the University of British Columbia Industry<br />

Liaison Office on behalf of Fraser Health<br />

• Overall co-ordination of all approvals required for the conduct of research in FH.<br />

• Education <strong>and</strong> Communication: Coordinated by Department of Evaluation <strong>and</strong> Research Services<br />

[1 staff ]. Includes: education in research methods (e.g. skill development workshops; training in<br />

ethical <strong>and</strong> regulatory requirements for clinical trials)


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BRITISH COLUMBIA<br />

• Knowledge Translation: Library Services, publication support [9 FTE].<br />

Quality control/ assurance procedures are based on Health Canada <strong>and</strong> FDA regulations. The Department<br />

of Evaluation <strong>and</strong> Research Services produces <strong>and</strong> makes available a Research Quality Improvement<br />

Manual which lays out the process for ongoing monitoring of research studies. All projects are<br />

approved by the Fraser Health Research Ethics Board prior to initiation.<br />

Fraser Health is a participant in the <strong>Clinical</strong> Research Professional Development (CPRD) Education Program<br />

(described in Appendix 5). This has a curriculum directed to research coordinators <strong>and</strong> is coordinated<br />

amongst the Lower Mainl<strong>and</strong> academic health centres.<br />

Contact:<br />

Chunick, Susan. Director, Department of Evaluation <strong>and</strong> Research Services. Tel: 604-587-4681. susan.<br />

chunick@fraserhealth.ca.<br />

Vancouver Coastal Health<br />

Vancouver Coastal Health Research Institute (VCHRI) <strong>Clinical</strong> Research Unit<br />

The VCHRI <strong>Clinical</strong> Research Unit (CRU) (www.vchri.ca/s/CRU.asp) is based at the Gordon & Leslie Diamond<br />

Health Care Centre. It supports investigators in all disciplines at Vancouver Coastal Health <strong>and</strong><br />

UBC in their conduct of clinical trials. Investigators request CRU services for industry Phases II, III, <strong>and</strong> IV<br />

trials, grant funded trials, or investigator-initiated research. Fees for services are based on the complexity<br />

of the services requested <strong>and</strong> funding for the research The CRU offers:<br />

• Assistance with protocol development<br />

• Develop informed consent documents<br />

• Recruiting<br />

• Screening <strong>and</strong> consenting subjects<br />

• Study interviews<br />

• Venipuncture <strong>and</strong> serum <strong>and</strong> plasma aliquot preparation<br />

• Physical exams <strong>and</strong> tests<br />

• Vaccine <strong>and</strong> medication administration<br />

• Adverse event reporting<br />

• Subject appointment booking <strong>and</strong> reminder calls<br />

• Monitor audits<br />

• REB submission assistance<br />

• Regulatory support with Health Canada/ FDA<br />

The Unit supports all CFRI researchers as needed. Many of these are listed in Appendix 6. The unit is new<br />

<strong>and</strong> growing. Current staffing is as follows (total = 2), with an anticipated two to four additional coordinators<br />

to be hired by the summer of 2010.<br />

Study Nurses/ Coordinators<br />

Data Managers/ Coordinators<br />

Laboratory & Pharmacy<br />

Staff<br />

Admin. (<strong>Clinical</strong><br />

Research Managers)<br />

Epidemiologists/<br />

Statisticians<br />

1.5* 0 0 0.5 Collaborate with<br />

C2E2**<br />

* Also involved in the administrative aspects of clinical trials (e.g., REB submissions, regulatory documentation), budgeting <strong>and</strong> accounts,<br />

study design, <strong>and</strong> training of assistants.<br />

** C2E2 is the Centre for <strong>Clinical</strong> Epidemiology & Evaluation at VCHRI (www.c2e2.vchri.ca/), which offers expertise in study design,<br />

data collection <strong>and</strong> management, statistical analysis, systematic reviews, <strong>and</strong> health economics.


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103<br />

For Quality Control/Assurance, SOPs are in place for consent <strong>and</strong> phlebotomy <strong>and</strong> are being developed<br />

for other research related processes. A checklist is completed for all contracts ensuring protocols<br />

<strong>and</strong> consents have been approved by the REB. All subject personal information is maintained<br />

on password protected computers which are in locked offices or the information in maintained in<br />

a locked office. Access to the information is limited to authorized personnel. As well as attending<br />

research training sessions offered by the British Columbia Health Authorities, all staff complete the<br />

Tri-Council Policy Statement (TCPS) training for the Ethical Conduct for Research Involving Humans<br />

<strong>and</strong> each staff member is regularly observed during the consent process.<br />

Contact:<br />

Feschuk, Connie. Manager. Tel: 604-875-5886. connie.feschuk@vch.ca.<br />

Vancouver Isl<strong>and</strong> Health Authority<br />

VIHA Research Department<br />

The VIHA Research Department supports in-patient <strong>and</strong> out-patient industry-sponsored <strong>and</strong> investigator-driven<br />

trials within the 18 hospitals managed by Vancouver Isl<strong>and</strong> Health Authority (VIHA)<br />

(www.viha.ca/rnd/). These hospitals include Royal Jubilee, Victoria General, <strong>and</strong> Nanaimo Regional<br />

General Hospitals. The Department offers the following services:<br />

• Administration <strong>and</strong> Trial coordination<br />

• Financial Management<br />

• <strong>Clinical</strong> Trial Agreement review<br />

• Liaison with Industry<br />

• Research Ethics Submissions <strong>and</strong> ongoing correspondence<br />

• Quality control <strong>and</strong> supervision of all operational techniques <strong>and</strong> research activities in keeping<br />

with international guidelines<br />

• Clinic space available for patient assessments<br />

• Assurance of protocol compliance <strong>and</strong> quality control of data h<strong>and</strong>ling in compliance with<br />

Good <strong>Clinical</strong> Practice (GCP) <strong>and</strong> applicable regulatory requirements<br />

• St<strong>and</strong>ard Operating Procedures.<br />

The Department currently supports 30 investigators in Phases II, III, <strong>and</strong> IV clinical trials. Investigator<br />

details are listed in Appendix 6:<br />

• Backman, Catherine • Jackson, ML • Petrunia, Dennis<br />

• Barclay A • Jones, C • Piper, HG<br />

• Behrens, C • Kibsey, P • Popkin JS<br />

• Burnett, Stephen • Kirk, P • Schimmele, C<br />

• Connolly, M • Lerch, L • Singh, RA<br />

• Daly, D • Miller, D • Tan Dy, C<br />

• Harder, Curtis • Morris, Dorothy • Tang, Bao<br />

• Hayashi, A • Orrom, William • Weinerman, R<br />

• Hrebicek, O • Penn Andrew • Williams, R<br />

• Horgan, K • Person, D • Wood, G


104<br />

BRITISH COLUMBIA<br />

Its staffing is as follows:<br />

Study Nurses/ Coordinators<br />

Data Managers/ Coordinators<br />

Laboratory & Pharmacy<br />

Staff<br />

Admin.<br />

6 0 0 3 3 *<br />

* Two involved in capacity building <strong>and</strong> one in special projects.<br />

The Department uses hospital pharmacies <strong>and</strong> laboratories in the conduct of clinical trials, as well as<br />

external pharmacies.<br />

The VIHA has a full research ethics board structure that oversees the process for getting trials approved<br />

(http://www.viha.ca/rnd/research_ethics) (see Appendix 4). Studies are in full compliance with FDA/<br />

Health Canada regulations <strong>and</strong> the Department provides ongoing staff training in clinical trials <strong>and</strong> GCP.<br />

Contact:<br />

Patel, Anika. Acting Regional Manager. Tel: 250-370-8764. anika.patel@viha.ca.<br />

Other


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

105<br />

APPENDICES 3-5<br />

Appendix 3.<br />

Quality Control/ Quality Assurance at B.C.’s <strong>Clinical</strong> <strong>Trials</strong> Units, Centres, <strong>and</strong> Study Sites 106<br />

Appendix 4. B.C. Research Ethics Boards 107<br />

Appendix 5. <strong>Clinical</strong> <strong>Trials</strong> Training Facilities 108


106<br />

BRITISH COLUMBIA<br />

APPENDIX 3.<br />

QUALITY CONTROL/ QUALITY ASSURANCE AT B.C.’S<br />

CLINICAL TRIALS UNITS, CENTRES, AND STUDY SITES<br />

Eighteen facilities were visited <strong>and</strong> interviewed for this report. SOPs <strong>and</strong> other documentation<br />

involved in the assurance of quality <strong>and</strong> maintenance of consistency were reviewed. All facilities had<br />

documentation pertaining to:<br />

• Informed consent<br />

• Compliance with Health Canada, FDA, <strong>and</strong> ICH GCP regulations <strong>and</strong> guidelines.<br />

Furthermore, since all sites obtain written approval to conduct a clinical trial from a duly constituted<br />

Research Ethics Board prior to commencement, all units:<br />

• Maintain confidentiality (in addition, confidentiality is part of the informed consent, <strong>and</strong> all units<br />

follow Canada’s stringent privacy laws; furthermore, for completeness, 2/3 had additional separate<br />

written documentation regarding confidentiality)<br />

• Report adverse events to sponsors <strong>and</strong> regulators (<strong>and</strong> more than 2/3 had additional separate<br />

written documentation regarding this)<br />

• Adhere to the REB requirements for protocol amendments, ongoing review, <strong>and</strong> clinical trial status<br />

reports.<br />

Moreover, at least half the units had written documentation (usually SOPs) pertaining to:<br />

• The REB process<br />

• Collection of blood<br />

• Process for accepting trials into the unit • Collection of other biological samples<br />

• Study initiation<br />

• H<strong>and</strong>ling of other biological samples<br />

• Data collection<br />

• SOP updating requirements<br />

• Data management<br />

• Training requirements<br />

• Data reporting to sponsor<br />

• Activity Responsibilities<br />

• Management of adverse events<br />

Other written documentation, again mainly in the form of SOPs, included:<br />

• Procedures for contracting services such as statistics, budgeting, contracts support<br />

• H<strong>and</strong>ling of blood<br />

• Data analysis<br />

• Investigational Drug H<strong>and</strong>ling<br />

• Study Closure<br />

• Recruiting<br />

• Archiving<br />

• Communication<br />

• QA procedures


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107<br />

APPENDIX 4. B.C. RESEARCH ETHICS BOARDS<br />

Information from The Ethics Review Process in British Columbia: An Environmental Scan. Michael Smith Foundation for Health Research. October 2007.<br />

www.msfhr.org/resources/public/Reports/BC_Scan.pdf. Accessed October 21, 2009.<br />

Data valid to 2007. REB = Research Ethics Board.<br />

REBs Associated with Institution/ Organization Type of Institution/ Organization Year REB Established<br />

B.C. Cancer Agency Health Services Academic 2003<br />

B.C. Institute of Technology Academic 1999<br />

Camosun College Academic 2006<br />

Canadian Blood Services (B.C.) Health Services (national NGO) 2001<br />

Community-Based REB Community 1999<br />

Fraser Health Health Services 2004<br />

Interior Health Health Services 2005<br />

Inter Tribal Health Authority Aboriginal (in progress 2007)<br />

Kwantlen University College Academic 2002<br />

Malaspina University-College Academic 2002<br />

Northern Health Health Services 2007<br />

Providence Health Care Health Services 1996<br />

Royal Roads University Academic 2000<br />

Simon Fraser University Academic 1996<br />

Thompson Rivers University Academic 2001<br />

Trinity Western University Academic 1995<br />

University College of the Fraser Valley Academic 2002<br />

University of British Columbia (also reviews Vancouver Coastal Health <strong>and</strong> Provincial Health Services Academic <strong>Clinical</strong>: 1983 Behavioural: 1976<br />

Authority except adult oncology)<br />

University of Northern B.C. Academic-Medical Faculty 1994<br />

University of Victoria Academic-Medical Faculty 1999<br />

The Vancouver Foundation Community 2004<br />

Vancouver Isl<strong>and</strong> Health Authority: <strong>Clinical</strong>* Health Services 1987<br />

Vancouver Isl<strong>and</strong> Health Authority :Health** Health Services 2006


108<br />

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APPENDIX 5. CLINICAL TRIALS TRAINING FACILITIES<br />

Organization Contact Name/ URL Description of Training <strong>and</strong> Courses Number <strong>and</strong> Type of<br />

Staffing<br />

ASKA Research See Appendix 11 for information Offers numerous online training courses.<br />

Offers clinical research education to investigators <strong>and</strong> clinical research coordinators.<br />

CHEOS <strong>Clinical</strong> Education<br />

Series<br />

<strong>Clinical</strong> Research Professional<br />

Development (CRPD)<br />

Education Program<br />

<strong>and</strong><br />

CFRI Monthly Education<br />

Forum<br />

Three sites:<br />

• CFRI Child <strong>and</strong> Family<br />

Research Institute<br />

• Providence Health Care<br />

Research Institute<br />

• Vancouver Coastal Research<br />

Institute<br />

Global Client Partners<br />

Consulting Inc.<br />

See Appendix 2 for information<br />

on CHEOS<br />

Child <strong>and</strong> Family Research<br />

Institute<br />

Manager Research Education:<br />

S<strong>and</strong>ra Elias<br />

selias@cw.bc.ca<br />

Tel : (604) 875 3722.<br />

___________<br />

Vancouver Coastal Health<br />

Research Institute<br />

Co-ordinator, Research Education<br />

Kerri Abramson<br />

kerri.abramson@vch.ca<br />

Tel : 604 875 4111 x 67793<br />

www.cfri-training.ca/training/<br />

<strong>Clinical</strong>ResearchCoordinators.asp<br />

CRPD supports professional development of clinical research coordinators <strong>and</strong> research<br />

staff involved in all aspects of clinical research. It is focused on the Lower Mainl<strong>and</strong>, with<br />

the potential to broaden the initiative throughout B.C.<br />

The CRPD program is an education initiative led by a group of individuals committed to<br />

supporting the professional development of clinical research coordinators, managers <strong>and</strong><br />

others involved in clinical research from the Lower Mainl<strong>and</strong>’s teaching hospitals’ research<br />

institutes. It offers seminars <strong>and</strong> workshops in accordance with a structured curriculum.<br />

Attendees can receive a certificate of attendance for documentation of their participation<br />

which can be used for continuing education credits.<br />

The CRPD program comprises quarterly workshops on topics including:<br />

• GCP<br />

• Budgeting <strong>and</strong> Finance<br />

• Ethics <strong>and</strong> Regulatory Issues<br />

• Human Resources<br />

• Communication Skills<br />

• Project Management<br />

CFRI also provides a monthly education forum specific to <strong>Clinical</strong> Research Coordinators.<br />

The purpose of these sessions is to provide an education forum specific to clinical research.<br />

4-6 persons located in<br />

Vancouver<br />

See Appendix 11 for information One-on-one or group training as requested by the client. Full time administrative head<br />

office staff; but primarily<br />

contract staff to ensure low<br />

cost services to the client


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

109<br />

Organization Contact Name/ URL Description of Training <strong>and</strong> Courses Number <strong>and</strong> Type of<br />

Staffing<br />

Health Information Science<br />

(HIS)<br />

University of Victoria<br />

University of Victoria<br />

PO Box 3050 STN CSC<br />

Victoria B.C. V8W 3P5<br />

Tel: 250-721-8575<br />

Fax: 250-472-4751<br />

his@uvic.ca<br />

Associate Professor <strong>and</strong> Director<br />

Andre Kushniruk<br />

Contact: Denis Protti, Professor<br />

<strong>and</strong> Graduate Advisor<br />

Tel: 250-721-8814<br />

dprotti@uvic.ca<br />

Assistant to the Director: Leslie<br />

Wood<br />

Tel: 250-721-8576<br />

lwood@uvic.ca<br />

HIS offers a range of courses in healthcare management, epidemiology <strong>and</strong> medical methodology;<br />

with some aspects of courses <strong>and</strong> training relevant to <strong>Clinical</strong> <strong>Trials</strong> management<br />

<strong>and</strong> <strong>Clinical</strong> <strong>Trials</strong> operations.<br />

HIS provides courses to train students in the identification of information <strong>and</strong> data needed<br />

by doctors, nurses, hospital administrators, government planners <strong>and</strong> other health care<br />

professionals <strong>and</strong> how they are used in order to make effective health care decisions.<br />

Relevant undergraduate courses include:<br />

• Epidemiology<br />

• Medical methodology<br />

• Healthcare ethics <strong>and</strong> project management.<br />

Graduate studies<br />

HIS offers programs of study leading to the degree of MSc. The school also offers an oncampus<br />

special arrangements program of study leading to the degree of PhD in Health<br />

Information Science. The School has well established linkages to health care organizations<br />

within B.C. <strong>and</strong> Canada that allow faculty <strong>and</strong> student to conduct research in a variety of<br />

health related field settings.<br />

Health Information Science<br />

UVic employs:<br />

8 Faculty members<br />

6 Faculty staff<br />

30 Adjunct Faculty members<br />

2 associate professionals


110<br />

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APPENDIX 5. <strong>Clinical</strong> <strong>Trials</strong> Training Facilities (cont’d)<br />

Organization Contact Name/ URL Description of Training <strong>and</strong> Courses Number <strong>and</strong> Type of<br />

Staffing<br />

School of Population & Public<br />

Health<br />

UBC<br />

James Mather Building<br />

5804 Fairview Avenue<br />

Vancouver, B.C. V6T 1Z3<br />

Tel: 604-822-2772<br />

Fax: 604-822-4994<br />

www.spph.ubc.ca<br />

Director: Dr. Martin Schechter<br />

Contact: Rhonda Tolley<br />

Tel: 604-822-3910<br />

rhonda.tolley@ubc.ca<br />

School of Population & Public Health offers a range of courses in epidemiology <strong>and</strong><br />

healthcare; with several directly relevant to <strong>Clinical</strong> <strong>Trials</strong> management <strong>and</strong> <strong>Clinical</strong> <strong>Trials</strong><br />

operations. Its main teaching focus is graduate education in areas ranging from public<br />

health to health policy.<br />

Academic programs <strong>and</strong> attainments include :<br />

• MHA Master of Health Administration<br />

• MHSc Master of Health Science<br />

• MPH Master of Public Health<br />

• MSc Master of Science<br />

• PhD Doctor of Philosophy<br />

• Community Medicine Residency.<br />

Masters Courses relevant to <strong>Clinical</strong> <strong>Trials</strong> training include:<br />

• The Design <strong>and</strong> Analysis of <strong>Clinical</strong> <strong>Trials</strong>.<br />

Ethical considerations, intention-to-treat versus efficacy trials, principles of sampling <strong>and</strong><br />

exclusion, methods of allocation <strong>and</strong> techniques of r<strong>and</strong>omization, parallel versus cross<br />

over design, monitoring treatment outcomes, adverse effects, stopping rules, analytic<br />

techniques <strong>and</strong> data interpretation, <strong>and</strong> logistical issues in the management of clinical<br />

trials.<br />

• <strong>Clinical</strong> Epidemiology.<br />

Principles <strong>and</strong> methods of epidemiology are applied to clinical problems. Evaluation <strong>and</strong><br />

design of laboratory <strong>and</strong> clinical tests <strong>and</strong> of therapeutic interventions.<br />

• <strong>Clinical</strong> Decision Analysis.<br />

Methodology in <strong>and</strong> applicability of clinical decision analysis. Applications in problem<br />

solving (screening or prevention program assessment, test of treatment trade-offs, interpreting<br />

uncertain clinical data etc). Techniques include decision tree design, sub-trees,<br />

marker models, sensitivity analysis, Monte Carlo simulation, threshold analysis, utility<br />

assessment including the DEALE.<br />

• <strong>Clinical</strong> Research Methods for Surgical Procedures.<br />

The application of r<strong>and</strong>omized trial methods in surgical disciplines <strong>and</strong> specifically to<br />

surgical procedures has been increasing. The purpose of this course is to explore the use of<br />

r<strong>and</strong>omized trials in surgery.<br />

40 Faculty members<br />

7 Departmental staff<br />

51 Associate UBC Faculty<br />

57 <strong>Clinical</strong> Faculty<br />

60 Adjunct Faculty<br />

15 Emeritus Faculty


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

111<br />

Organization Contact Name/ URL Description of Training <strong>and</strong> Courses Number <strong>and</strong> Type of<br />

Staffing<br />

Society of <strong>Clinical</strong> Research<br />

Associates, Inc., Vancouver<br />

Chapter<br />

Western Regional Training<br />

Centre for Health Services<br />

Research (WRTC)<br />

Vancouver local chapter chairperson:<br />

Erin Cherban erin_cherban@<br />

mail.cheos.ubc.ca<br />

www.socra.org<br />

School of Population <strong>and</strong> Public<br />

Health<br />

5804 Fairview Avenue<br />

Vancouver B.C. V6T 1Z3<br />

Tel: 604-822-2827<br />

Fax: 604-822-4994<br />

wrtc.hsr@ubc.ca<br />

Director: Sam Sheps<br />

Sam.sheps@ubc.ca<br />

Tel: 604-822-3081<br />

Contact: Isabella Losinger,<br />

Program Manager<br />

Isabella.losinger@ubc.ca<br />

Tel: 604-822-2827<br />

http://wrtc-hsr.ca/<br />

A non-profit, professional organization dedicated to the continuing education <strong>and</strong><br />

development of clinical research professionals. It offers courses <strong>and</strong> workshops in subjects<br />

such as:<br />

• GCP<br />

• <strong>Trials</strong> management<br />

• SOPs<br />

• Monitoring<br />

• Legal, Ethical <strong>and</strong> Practical Considerations in Protecting Human Research Participants.<br />

WRTC is an innovative <strong>and</strong> collaborative initiative that supports the postgraduate training<br />

of applied health services researchers across disciplines, sectors, <strong>and</strong> institutions,<br />

equipping them to address the research needs of a wide range of health care policy <strong>and</strong><br />

decision-makers. Relevant courses include:<br />

• Health Care Research Methods<br />

• Epidemiology of Health Care<br />

WRTC is based at six universities in western Canada: University of Alberta, UBC, University<br />

of Calgary, University of Manitoba, University of Regina, <strong>and</strong> University of Saskatchewan.<br />

Graduate students (Masters or PhD) may participate in the program as full students or as<br />

affiliate students.<br />

9 faculty <strong>and</strong> staff across the<br />

six universities


112<br />

BRITISH COLUMBIA<br />

APPENDIX 6<br />

TABLE OF CONTENTS<br />

<strong>Clinical</strong> <strong>Trials</strong> Investigators in B.C. 113<br />

Endowed Chairs 113<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order 114<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty 170<br />

6.3 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Other Areas of Specialty 226<br />

Epidemiology, Health Economics, Health Outcomes 226<br />

Pediatrics 238


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

113<br />

APPENDIX 6. CLINICAL TRIALS INVESTIGATORS IN B.C.<br />

Following the table showing Endowed Chairs, clinical trials investigators are listed in (1) full alphabetical order, (2) according to disease area specialty,<br />

<strong>and</strong> (3) according to other specialties (epidemiology, health economics, health outcomes, pediatrics). Email addresses <strong>and</strong> URLs are correct to January<br />

2010.<br />

Endowed Chairs<br />

The following table lists the 16 investigators who hold endowed Chairs. Their details can be found in the following listings.<br />

INVESTIGATOR INSTITUTION ENDOWED CHAIR<br />

Buller, Christopher Van Coastal Health Research Institute Sauder Family Heart <strong>and</strong> Stroke Foundation Chair in Cardiology<br />

Fischer, Benedikt CIHR/PHAC Research Chair in Applied Public Health<br />

Gleave, Martin Van Coastal Health Research Institute Liber Ero B.C. Leadership Chair in Prostate Research<br />

Hayden, Michael Child & Family Research Institute CRC Human Genetics <strong>and</strong> Molecular Medicine<br />

Honer, William Van Coastal Health Research Institute Jack Bell Chair in Schizophrenia Research<br />

Knight, Darryl Providence Health Care Research Institute CRC Airway Disease<br />

Lear, Scott Providence Health Care Research Institute Pfizer/Heart & Stroke Foundation of B.C. & Yukon Chair in Cardiovascular Prevention<br />

Research<br />

Marra, Carlo Van Coastal Health Research Institute CRC in Pharmaceutical Outcomes<br />

Puil, Ernie UBC Campus Jean Templeton Hugill Chair<br />

Rieckmann, Peter Van Coastal Health Research Institute Multiple Sclerosis Society of Canada Research Chair<br />

Schechter, Martin Providence Health Care Research Institute CRC HIV/AIDS <strong>and</strong> Urban Population Health<br />

Sin, Donald Providence Health Care Research Institute CRC Chronic Obstructive Pulmonary Disease<br />

Smith, Clayton Van Coastal Health Research Institute CRC in Cell Therapies<br />

Stoessl, A Jonathan Van Coastal Health Research Institute CRC CNS Disorders<br />

Wasan, Kishor UBC Campus CIHR/iCo Therapeutics Research Chair in Drug Delivery for Neglected Global<br />

Diseases.<br />

Young, Allan Van Coastal Health Research Institute Leading Edge Endowment Fund (LEEF) Chair in Depression Research<br />

CIHR = Canadian Institutes of Health Research (www.cihr-irsc.gc.ca); CRC = Canada Research Chair (www.chairs-chaires.gc.ca). PHAC = Public Health Agency of Canada (www.phac-aspc.gc.ca).


114<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Abel, James Cardiovascular<br />

Surgery<br />

Abu-Laban,<br />

Riyad<br />

Agranovich,<br />

Alex<strong>and</strong>er<br />

Alexiadis,<br />

Alex<strong>and</strong>ros<br />

Alimenti,<br />

Ariane<br />

Al-Tourah,<br />

Abdul<br />

Amed,<br />

Shazhan<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Surgery UBC Providence Health Care Research<br />

Institute<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

Radiation<br />

Oncology<br />

& Developmental<br />

Radiotherapeutics<br />

jabel@providencehealth.<br />

bc.ca<br />

abulaban@interchange.<br />

ubc.ca<br />

www.ctsnet.org/home/<br />

jabel<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=61951&_<br />

Type=Researchers-Data-<br />

base&_Title=Abu-Laban-<br />

Dr.-Riyad-B.<br />

UBC B.C. Cancer Agency N/A http://www.surgery.ubc.<br />

ca/faculty/aagranovich.<br />

html<br />

CV / cardiology Surgery<br />

Critical care, Emergency<br />

medicine<br />

N/A<br />

Cancer Prostate<br />

Fraser Health N/A N/A Other Palliative care<br />

Pediatrics Medicine UBC Child & Family Research Institute aalimenti@cw.bc.ca N/A ID/ infection HIV<br />

B.C. Cancer Agency aaltoura@bccancer.bc.ca N/A Cancer Breast, lymphoma<br />

Pediatrics Medicine UBC Child & Family Research Institute samed@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=305<br />

Metabolic/ endocrine Diabetes<br />

Amil, S B.C. Cancer Agency N/A N/A Cancer Gastro-intestinal<br />

Anderson,<br />

Frank H<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

franka@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=150<br />

74854<br />

Gastro-intestinal, ID/<br />

infection<br />

Colitis, Crohn's,<br />

hepatitis


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

115<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Anderson, H. B.C. Cancer Agency N/A N/A Cancer Gastro-intestinal,<br />

lung<br />

Anis, Aslam Population &<br />

Public Health<br />

Ansermino,<br />

Mark<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Ansley, David Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Ashton,<br />

Thomas<br />

Atkins, M<br />

Stella<br />

Attwell,<br />

Andrew<br />

Auersperg,<br />

Edward<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

aslam.anis@ubc.ca http://www.mhanet.ca/<br />

search/node/15<br />

UBC Child & Family Research Institute mansermino@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.aspID=3<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Interior Health Authority-Penticton<br />

Regional Hospital<br />

School of<br />

Computing<br />

Science<br />

General Internal<br />

Medicine<br />

david.ansley@vch.ca http://www.apt.ubc.ca/<br />

anesthesiology/Vancouver_General_Hospital/<br />

Department_Members/<br />

Dr_David_Ansley.htm<br />

N/A www.directory.ubc.ca/<br />

index.cfm<br />

SFU stella@cs.sfu.ca http://www.cs.sfu.<br />

ca/~stella/<br />

CV / cardiology,<br />

metabolic/ endocrine<br />

Hypertension,<br />

obesity<br />

Anesthesiology Pediatrics<br />

CV / cardiology Coronary bypass<br />

CV / cardiology Acute coronary<br />

syndrome<br />

Cancer Melanoma, radiotherapy/<br />

imaging<br />

B.C. Cancer Agency N/A N/A Cancer Breast, prostate<br />

Medicine UBC Fraser Health e@auersperg.ca N/A CV / cardiology<br />

Ayas, Najib Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Aymong, Eve Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Backman,<br />

Catherine<br />

UBC Van Isl<strong>and</strong> Health Authority-<br />

Nanaimo, Campbell River<br />

Bai, Tony Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

najib.ayas@vch.ca http://ubc-sleepdisorders.<br />

vch.ca/ayas.htm<br />

Critical care, pulmonary<br />

eaymong@providencehealth.bc.ca<br />

http://www.biomedexperts.com/Profile.<br />

bme/63107/Eve_D_Aymong<br />

Apnea<br />

CV / cardiology Acute coronary<br />

syndrome<br />

N/A N/A Musculo-skeletal Orthopedics/rehab<br />

tony.bai@hli.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_tony_<br />

bai.shtml<br />

Pulmonary Asthma, bronchiastasis,<br />

COPD, fibrosis


116<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Balneaves,<br />

Lynda<br />

Nursing Applied<br />

Science<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

UBC Van Coastal Health Research<br />

Institute<br />

lynda.balneaves@nursing.<br />

ubc.ca<br />

http://www.nursing.<br />

ubc.ca/faculty/biopage.<br />

aspxc=65.5133574166368<br />

Barclay A Van Isl<strong>and</strong> Health Authority N/A N/A Neonatology<br />

CV / cardiology<br />

Bardal, Stan K Medical <strong>Sciences</strong><br />

Barnett,<br />

Jeffrey Ben<br />

Barnett,<br />

Michael<br />

Basson,<br />

Rosemary<br />

Beauchamp,<br />

Richard<br />

Beckham,<br />

Wayne Allan<br />

Health Information<br />

Science<br />

UVic bardals@uvic.ca http://www.zoominfo.com/people/Bardal_<br />

Stan_1207852047.aspx<br />

UVic B.C. Cancer Agency jebarnet@uvic.ca N/A Cancer<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

Orthopedics Medicine UBC Child & Family Research Institute rbeauchamp@cw.bc.ca;<br />

beaucham@interchange.<br />

ubc.ca<br />

Physics &<br />

Astronomy<br />

Begg, Iain Ophthalmology<br />

& Visual<br />

Science<br />

mbarnett@bccancer.bc.ca http://www.leukemiabmtprogram.org/general_<br />

information/about_us/<br />

our_doctors/barnett.html<br />

sexmed@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

750943<br />

http://www.orthosurgery.<br />

ubc.ca/faculty_bios/beauchamp.html<br />

UVic B.C. Cancer Agency wbeckham@bccancer.bc.ca http://www.phys.uvic.<br />

ca/medphys/people/WB/<br />

beckham.html<br />

UBC Van Coastal Health Research<br />

Institute<br />

begg@portal.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=518<br />

14651<br />

Cancer Prostate<br />

Cancer Leukemia<br />

Obstetrics / gynecology<br />

Reproduction<br />

CNS Brain injury<br />

Cancer Radiotherapy<br />

Metabolic/ endocrine Diabetes<br />

Behrens, C Van Isl<strong>and</strong> Health Authority N/A N/A Gastro-intestinal,<br />

cancer


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

117<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Bennett,<br />

Mary<br />

Bernstein,<br />

Vanessa<br />

Bernstein,<br />

Victoria<br />

Berrang,<br />

Tanya<br />

Berringer,<br />

Ross<br />

Bjornson,<br />

Bruce<br />

Black, Peter Urologic <strong>Sciences</strong><br />

Bond, R.<br />

James<br />

Bondy,<br />

Gregory<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute mbennett@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751067<br />

Metabolic/ endocrine Endocrinology<br />

Medicine UBC B.C. Cancer Agency vbernste@bccancer.bc.ca N/A Cancer Breast<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Surgery Radiation<br />

Oncology<br />

& Developmental<br />

Radiotherapeutics<br />

dr.bernstein@telus.net http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=41888&_<br />

Type=Researchers-Data-<br />

base&_Title=Bernstein-<br />

Dr.-Victoria<br />

UBC B.C. Cancer Agency N/A http://www.surgery.ubc.<br />

ca/faculty/berrang.html<br />

Surgery Medicine UBC Providence Health Care Research<br />

Institute<br />

CV / cardiology Acute coronary<br />

syndrome<br />

Cancer Breast<br />

N/A N/A CV / cardiology Coronary disease<br />

Pediatrics Medicine UBC Child & Family Research Institute bbjornson@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=387<br />

Pathology &<br />

Laboratory<br />

Med<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

N/A www.prostatecentre.<br />

com/aboutus/aboutus.<br />

phppageID=187<br />

CNS Stroke, epilepsy<br />

Genitourinary, cancer Bladder cancer<br />

Fraser Health N/A N/A Surgery Thoracic surgery,<br />

cancer<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

gbondy@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=717<br />

98641<br />

CV / cardiology,<br />

metabolic/ endocrine<br />

Cardiovascular<br />

disease, diabetes


118<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Bonet, Jorge<br />

Federico<br />

Bowering,<br />

John<br />

Anesthesia Medicine UBC Providence Health Care Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Fraser Health N/A N/A CV / cardiology Cardiology<br />

jkbow@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=768<br />

71500<br />

CV / cardiology, anesthesiology<br />

Hypertension<br />

Bozek, Chris Fraser Health N/A N/A CNS Stroke<br />

CNS, dermatology ALS, inflammatory<br />

Briemberg,<br />

Hannah<br />

Brotto, Lori Obstetrics &<br />

Gynecology<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine UBC Women's Health Research<br />

Institute<br />

Brown, Carl Surgery Medicine UBC Providence Health Care Research<br />

Institute/ B.C. Cancer Agency<br />

hbriemberg@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmupdate<br />

=yes&page=personDetail<br />

&row=1000006607<br />

lori.brotto@vch.ca www.whri.org/projects<strong>and</strong>people/people/<br />

Brotto.htm<br />

cbrown@providencehealth.<br />

bc.ca<br />

http://www.providencehealthcare.org/colorectalsurgery/Carl-Brown.html<br />

Cancer, obstetrics /<br />

gynecology<br />

Cervical, endometrial,<br />

gynecology<br />

Cancer, CNS Colorectal, pain<br />

Brown, Sean Fraser Health N/A N/A Musculo-skeletal Orthopedics<br />

Dental<br />

Brunette,<br />

Donald<br />

Brunstein,<br />

John<br />

Buller,<br />

Christopher<br />

Oral Biological<br />

& Medical SCI<br />

Biochemistry &<br />

Molec Biology<br />

Dentistry UBC UBC Campus brunette@interchange.<br />

ubc.ca<br />

http://www.dentistry.ubc.<br />

ca/research/brunette.html<br />

Medicine UBC Child & Family Research Institute jbrunstein@cw.bc.ca http://www.pathology.<br />

ubc.ca/NewPathology/<br />

<strong>Clinical</strong>AssistantProfessor/<br />

John_Brunstein.html<br />

Cardiology Medicine UBC Van Coastal Health Research<br />

Institute<br />

cehbuller@shaw.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=41916&_<br />

Type=Researchers-Data-<br />

base&_Title=Buller-Dr.-<br />

Christopher-E.<br />

ID/ infection Respiratory<br />

CV / cardiology Acute coronary<br />

syndrome


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

119<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Burdge, David Infectious<br />

Diseases<br />

Burnett,<br />

Stephen<br />

Butler, Blair Obstetrics &<br />

Gynecology<br />

Byrne,<br />

Michael<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Child & Family Research Institute dburdge@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=257<br />

ID/ infection HIV<br />

Van Isl<strong>and</strong> Health Authority stephen.burnett@viha.ca N/A Musculo-skeletal Orthopedics<br />

Medicine UBC Child & Family Research Institute bbutler@cw.bc.ca N/A Obstetrics / gynecology<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

michael.byrne@vch.ca N/A Gastro-intestinal<br />

Cabral, David Pediatrics Medicine UBC Child & Family Research Institute dcabral@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=289<br />

Carere,<br />

Ronald<br />

Carpenito,<br />

Gerardo<br />

Cardiology Medicine UBC Providence Health Care Research<br />

Institute<br />

rcarere@providencehealth.<br />

bc.ca<br />

http://www.heart<strong>and</strong>lung.ca/ron-carere/<br />

Pregnancy<br />

Autoimmune Rheumatology,<br />

osteoporosis<br />

CV / cardiology Coronary artery<br />

disease<br />

Fraser Health N/A N/A Genitourinary Nephrology<br />

Carter, Diana Psychiatry Medicine UBC Child & Family Research Institute diana.carter@ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

750945<br />

Chambers,<br />

Keith<br />

Health Care/<br />

Epidemiology<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

kchamber@vanhosp.bc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=54732&_<br />

Type=Researchers-Data-<br />

base&_Title=Chambers-<br />

Dr.-G.-Keith<br />

Obstetrics / gynecology<br />

Gynecology<br />

Cancer Prostate<br />

Chan, Albert Fraser Health N/A N/A CV / cardiology Coronary disease,<br />

stroke


120<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Chan, Sammy Cardiology Medicine UBC Providence Health Care Research<br />

Institute<br />

Chanoine,<br />

Jean-Pierre<br />

Chapman,<br />

Kristine<br />

Cheung,<br />

Anson<br />

Cheung,<br />

Anthony P<br />

Cheung,<br />

Stephen<br />

Cheung,<br />

Winson<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

schan@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

752746<br />

Pediatrics Medicine UBC Child & Family Research Institute jchanoine@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=20<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Surgery Medicine UBC Providence Health Care Research<br />

Institute<br />

Obstetrics &<br />

Gynecology<br />

Chew, Ben Urologic <strong>Sciences</strong><br />

kristinechapman@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

011048<br />

acheung@providencehealth.<br />

bc.ca<br />

Medicine UBC Child & Family Research Institute apcheung@interchange.<br />

ubc.ca<br />

acheung3@cw.bc.ca<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

http://www.providencehealthcare.org/heart_centre/pop_upA32AnsonCheung.html;<br />

http://www.<br />

surgery.ubc.ca/faculty/<br />

acheung.html<br />

http://www.obstgyn.<br />

ca/About/dir_profile.<br />

htmlID=14<br />

CV / cardiology,<br />

metabolic<br />

Metabolic/ endocrine Growth<br />

Coronary artery<br />

disease, obesity<br />

Metabolic/ endocrine Diabetes<br />

CV / cardiology Cardiovascular<br />

disease, surgery<br />

Obstetrics / gynecology<br />

Reproduction<br />

Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

B.C. Cancer Agency N/A N/A Cancer<br />

ben.chew@ubc.ca www.prostatecentre.<br />

com/aboutus/aboutus.<br />

phppageID=178<br />

Chi, Kim Oncology Medicine UBC B.C. Cancer Agency kchi@bccancer.bc.ca http://www.prostatecentre.com/aboutus/aboutus.<br />

phppageID=166<br />

Genitourinary Renal<br />

Cancer, genitourinary Prostate


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

121<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Chia, Stephen Oncology Medicine UBC B.C. Cancer Agency schia@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=100<br />

0001161; http://www.<br />

eventcare.ca/clients/cowc/<br />

bios/stephen_chia.html<br />

Chilvers, Mark Pediatrics Medicine UBC Child & Family Research Institute mchilvers@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

016640<br />

Chittock,<br />

Dean<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Chiu, Anthony Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Chockalingam,<br />

Arum<br />

Health <strong>Sciences</strong><br />

Choi, Peter Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Chow, Victor<br />

DW<br />

Christenson,<br />

Jim<br />

Urologic <strong>Sciences</strong><br />

Clarke, Lorne Medical<br />

Genetics<br />

dean.chittock@vch.ca http://www.biomedexperts.com/Profile.<br />

bme/234409/Dean_R_<br />

Chittock<br />

antchiu@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=133<br />

287841<br />

SFU achockal@sfu.ca www.fhs.sfu.ca/portal_memberdata/arun<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Surgery Medicine UBC Providence Health Care Research<br />

Institute<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

PeterT.Choi@vch.ca http://www.apt.ubc.ca/<br />

anesthesiology/Vancouver_General_Hospital/<br />

Department_Members/<br />

Dr_Peter_Choi.htm<br />

N/A http://www.ubcfertility.<br />

com/drchow.php<br />

jimchris@interchange.<br />

ubc.ca<br />

lclarke@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=24<br />

Cancer Breast, head/neck<br />

Pulmonary Cystic fibrosis<br />

Critical care Sepsis, thrombosis<br />

Genitourinary Renal<br />

CV / cardiology Hypertension<br />

Anesthesiology, CV /<br />

cardiology<br />

Cancer Urogenital<br />

N/A CV / cardiology Myocardial infarction<br />

Metabolic/ endocrine Genetic disease


122<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Clevel<strong>and</strong>, D. Interior Health Authority-Penticton<br />

Regional Hospital<br />

Cochrane,<br />

Doug<br />

Cogswell,<br />

Arthur<br />

Coldman,<br />

Andrew<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Surgery Medicine UBC Child & Family Research Institute dcochrane@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=26<br />

N/A N/A CV / cardiology Acute coronary syndrome,<br />

atherosclerosis,<br />

atrial fibrillation<br />

Pediatrics Medicine UBC Child & Family Research Institute acogswell@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

753861<br />

Population &<br />

Public Health<br />

Medicine UBC B.C. Cancer Agency acoldman@bccancer.bc.ca http://www.stat.ubc.<br />

ca/People/Home/index.<br />

phpperson=:coldman:<br />

Cole, Colm Anesthesia Medicine UBC Providence Health Care Research<br />

Institute<br />

Collier, T. Neurology Interior Health Authority-Royal<br />

Inl<strong>and</strong> Hospital<br />

Connolly,<br />

Mary<br />

cole@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=146<br />

969188<br />

CNS<br />

CV / cardiology Cardiovascular<br />

disease<br />

ID/ infection HPV<br />

CNS/ anesthesiology Pain<br />

N/A N/A CNS Stroke<br />

Pediatrics Medicine UBC Child & Family Research Institute mconnolly@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=379<br />

Connors, Joe Medicine Medicine UBC B.C. Cancer Agency JConnors@bccancer.bc.ca www.bccancer.bc.ca/RES/<br />

ResearchPrograms/LymphoidCancers/researchers.<br />

htm#connors<br />

Conway, Brian Anesthesia Medicine UBC Van Coastal Health Research<br />

Institute/ Providence Health Care<br />

Research Institute<br />

bconway@interchange.<br />

ubc.ca<br />

http://www.mhanet.ca/<br />

search/node/35<br />

CNS Epilepsy/ seizures<br />

Cancer Lymphoma<br />

ID/ infection Hepatitis, HIV


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

123<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Cooper, S. Interior Health Authority-Penticton<br />

Regional Hospital<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

N/A N/A Genitourinary Renal<br />

Crabb, Simon B.C. Cancer Agency N/A N/A Cancer Breast<br />

Gynecology<br />

Cundiff, Geoff Obstetrics &<br />

Gynecology<br />

Cunningham,<br />

C.<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Interior Health Authority-Vernon<br />

Jubilee Hospital<br />

gcundiff@providencehealth.<br />

bc.ca<br />

Curt, Armin Neurology Medicine UBC UBC Campus Armin.Curt@paralab.<br />

balgrist.ch<br />

Czerkawski,<br />

Barbara<br />

www.whri.org/projects<strong>and</strong>people/people/<br />

CundiffGeoff.htm<br />

Obstetrics / gynecology<br />

N/A N/A Surgery Orthopedics<br />

http://www.neuroscience.<br />

uzh.ch/research/aging_disorders/curt<br />

CNS SCI<br />

B.C. Cancer Agency bczerkaw@bccancer.bc.ca N/A Cancer Breast<br />

Daly, D Van Isl<strong>and</strong> Health Authority N/A N/A Gastro-intestinal<br />

Daroza,<br />

Gerald<br />

Fraser Health N/A N/A Genitourinary Renal<br />

Pulmonary Cystic fibrosis<br />

Davidson,<br />

George<br />

Pediatrics Medicine UBC Child & Family Research Institute gdavidson@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=173<br />

102098<br />

Davis, Jeffrey Pediatrics Medicine UBC Child & Family Research Institute jdavis@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=269<br />

Davison,<br />

Joyce<br />

Dawson,<br />

Keith<br />

Dawson,<br />

Peter<br />

Nursing UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

joyce.davison@vch.ca www.prostatecentre.<br />

com/aboutus/aboutus.<br />

phppageID=158<br />

kdaw@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=177<br />

713788<br />

Cancer, transplant GVHD<br />

Genitourinary, cancer Prostate cancer<br />

CV / cardiology Coronary disease<br />

N/A N/A CNS MS


124<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Delisle,<br />

Marie-France<br />

Devonshire,<br />

Virginia<br />

Dewet,<br />

Joseph<br />

Dhawan,<br />

Pankaj<br />

Dhingra,<br />

Vinay<br />

Dickson, G.<br />

Brentley<br />

Obstetrics &<br />

Gynecology<br />

INSTITUTION EMAIL WWEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Child & Family Research Institute mdelisle@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=30<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

vdev@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751733<br />

Obstetrics / gynecology<br />

CNS MS<br />

Family Practice Medicine UBC UBC Campus N/A N/A ID/ infection HIV<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Family Practice Medicine UBC Van Coastal Health Research<br />

Institute<br />

Pregnancy<br />

N/A N/A CNS Brain injury<br />

vinay.dhingra@vch.ca N/A Critical care<br />

N/A N/A Gastro-intestinal,<br />

cancer<br />

Dix, David Pediatrics Medicine UBC Child & Family Research Institute ddix@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=260<br />

Dobson,<br />

Simon<br />

Pediatrics Medicine UBC Child & Family Research Institute sdobson@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751085<br />

Dodek, Peter Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Dorscheid,<br />

Delbert<br />

Medicine Medicine<br />

- Critical<br />

Care<br />

UBC Providence Health Care Research<br />

Institute<br />

pedodek@interchange.<br />

ubc.ca<br />

http://www.thecarenet.ca/index.<br />

phpoption=com_conten<br />

t&task=view&ID=29&Ite<br />

mid=46<br />

ddorscheid@hli.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_del_<br />

dorscheid.shtml<br />

Cancer Complications<br />

ID/ infection Hepatitis, HPV, HSV,<br />

meningitis<br />

Critical care Diabetes<br />

Critical care, pulmonary<br />

COPD, inflammatory,<br />

ARDS


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

125<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Douglas,<br />

Joanne<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Child & Family Research Institute jdouglas@cw.bc.ca http://www.whri.org/<br />

projects<strong>and</strong>people/<br />

people/Douglas.htm<br />

Du Plessis, J. Interior Health Authority-Kelowna<br />

General Hospital<br />

Duncan, John<br />

A.<br />

Dunne, James<br />

V.<br />

Dutz, Jan Dermatology &<br />

Skin Science<br />

Dvorak,<br />

Marcel<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Obstetrics / gynecology<br />

Pregnancy<br />

N/A N/A Hematology, surgery Orthopedics<br />

john.duncan@shaw.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=41711&_<br />

Type=Researchers-Data-<br />

base&_Title=Duncan-Dr.-<br />

John-A.<br />

drjdunne@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=204<br />

769036<br />

Medicine UBC Child & Family Research Institute dutz@interchange.ubc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=35<br />

Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

Dyck, Chad Interior Health Authority-Penticton<br />

Regional Hospital<br />

Eisen, Andrew Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

vanspine@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=45184&_<br />

Type=Researchers-Data-<br />

base&_Title=Dvorak-Dr.-<br />

Marcel-F.<br />

Genitourinary, metabolic/<br />

endocrine<br />

CV / cardiology,<br />

autoimmune<br />

Renal<br />

Hypertension, GVHD<br />

Dermatology Inflammatory<br />

CNS SCI<br />

N/A N/A CV / cardiology<br />

eisen@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=214<br />

914754<br />

CNS MND


126<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Ellard, Susan Medical Oncology<br />

Elliott,<br />

Thomas<br />

Elwood,<br />

Richard Kevin<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

UBC B.C. Cancer Agency sellard@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

752752<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

tom.elliott@vch.ca<br />

tgelliot@interchange.ubc.ca<br />

Medicine Medicine UBC BC Centre for Disease Control kevin.elwood@bccdc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=219<br />

833890<br />

Enns, Rob Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Ervin, Frank General Internal<br />

Medicine<br />

Farquharson,<br />

Duncan<br />

renns@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001168<br />

Cancer Breast, renal,<br />

prostate, MDR,<br />

urogenital<br />

http://drtomelliott.com/ Metabolic/ endocrine,<br />

CV / cardiology<br />

ID/ infection TB<br />

Diabetes, cardiovascular<br />

disease<br />

Gastro-intestinal Crohn’s, colitis,<br />

esophageal/<br />

stomach<br />

Medicine UBC Fraser Health flervin@telus.net N/A CV / cardiology Acute coronary<br />

syndrome<br />

Fraser Health N/A N/A Obstetrics / gynecology<br />

Farrell, Kevin Pediatrics Medicine UBC Child & Family Research Institute kfarrell@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=38<br />

Feldman,<br />

Howard<br />

Fenster,<br />

Howard<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Urologic <strong>Sciences</strong><br />

hfeldman@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=130415&_<br />

Type=Researchers-Data-<br />

base&_Title=Feldman-<br />

Dr.-Howard-H.<br />

Medicine UBC Van Coastal Health Res Inst N/A http://urology.ubc.ca/<br />

faculty<br />

CNS Epilepsy/ seizures<br />

CNS Alzheimer’s<br />

Genitourinary Bladder


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

127<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Fenton, Dave Radiology UBC B.C. Cancer Agency davfent@yahoo.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

016418<br />

Fenwick, John Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Fera, Tharwat Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Filiatrault,<br />

Lyne<br />

Fischer,<br />

Benedikt<br />

Fisher,<br />

Charles<br />

Fitzgerald,<br />

Catherine<br />

Fitzgerald,<br />

Mark<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

Health <strong>Sciences</strong><br />

jfenwick@vanhosp.bc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=65490&_<br />

Type=Researchers-Data-<br />

base&_Title=Fenwick-<br />

Dr.-John<br />

tfera01@shaw.ca http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

Cancer Lung<br />

CNS, critical care Brain injury, sepsis<br />

Pulmonary COPD<br />

N/A N/A ID/ infection Wound<br />

SFU bfa11@sfu.ca www.fhs.sfu.ca/portal_<br />

memberdata/bfischer<br />

Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

vanspine@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=45360&_<br />

Type=Researchers-Data-<br />

base&_Title=Fisher-Dr.-<br />

Charles-G.<br />

Oncology Medicine UBC B.C. Cancer Agency cfitzger@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

003512<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

markf@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=40909&_<br />

Type=Researchers-Data-<br />

base&_Title=FitzGerald-<br />

Dr.-J.-Mark<br />

ID/ infection Infection<br />

CNS, cancer SCI, brain<br />

Cancer Gastro-intestinal<br />

Pulmonary Asthma, bronchiastasis.<br />

COPD


128<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Fleming,<br />

Jonathan<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

fleming@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=43275&_<br />

Type=Researchers-Data-<br />

base&_Title=Fleming-Dr.-<br />

Jonathan<br />

Forbes, John Pediatrics Medicine UBC Child & Family Research Institute jforbes@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=41<br />

Forrest,<br />

Donna<br />

Medicine Medicine UBC B.C. Cancer Agency dforrest@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

003478<br />

Forzley, Brian Interior Health Authority-Penticton<br />

Regional Hospital<br />

Fradet, Guy Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

Francis,<br />

Gordon<br />

Friedman,<br />

Jan M.<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Medical<br />

Genetics<br />

Frohlich, Jiri Pathology &<br />

Laboratory<br />

Med<br />

Fryer,<br />

Christopher<br />

CNS Narcolepsy<br />

ID/ infection HIV<br />

Cancer Leukemia<br />

N/A N/A Genitourinary Nephrology<br />

guy.fradet@ubc.ca http://www.surgery.ubc.<br />

ca/faculty/gfradet.html<br />

gfrancis@mrl.ubc.ca www.icapture.ubc.ca/<br />

who/who_bios_gordon_francis.shtml<br />

Medicine UBC Child & Family Research Institute frid@interchange.ubc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=43<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

jifr@interchange.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_jiri_<br />

frolich.shtml<br />

Pediatrics Medicine UBC Child & Family Research Institute cfryer@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=262<br />

CV / cardiology Coronary bypass<br />

CV / cardiology Cardiovascular<br />

disease<br />

CNS Mental health<br />

CV / cardiology Atherosclerosis,<br />

cholesteremia<br />

Cancer Brain/CNS


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

129<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Fung,<br />

Anthony Y-F.<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

funga@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=257<br />

342302<br />

Fyles, Gillian Family Practice UBC B.C. Cancer Agency gfyles@bccancer.bc.ca http://www.coag.uvic.ca/<br />

eolcare/gillian_fyles.htm<br />

Gagnon, Alain Obstetrics &<br />

Gynecology<br />

Ganesan,<br />

Soma<br />

Medicine UBC Women's Health Research<br />

Institute<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

Garbuz, Don Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

Gelmon,<br />

Karen<br />

Geoffrion,<br />

Roxana<br />

Gibson,<br />

Gillian<br />

CV / cardiology Acute coronary<br />

syndrome<br />

Cancer Palliative care<br />

soma.ganesan@vch.ca http://www.mhanet.ca/<br />

search/node/888<br />

garbuz@shaw.ca http://www.hiphealth.ca/<br />

People/Faculty.htm#g<br />

Oncology Medicine UBC B.C. Cancer Agency kgelmon@bccancer.bc.ca http://www.bccrc.ca/at/<br />

people_kgelmon.html<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Gill, John Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

agagnon@cw.bc.ca N/A Obstetrics/ gynecology<br />

rgeoffrion@providencehealth.bc.ca<br />

www.obstgyn.ca/About/<br />

dir_detail.htmID=469<br />

gillian.gibson@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=266<br />

719405<br />

jgill@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

006603<br />

Gill, Sharlene Oncology Medicine UBC B.C. Cancer Agency sgill@bccancer.bc.ca http://www.bccancer.<br />

bc.ca/RES/ResearchPrograms/bcpcr/people/<br />

faculty/sharlenegill.htm<br />

Gin, Kenneth Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

kenneth.gin@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=269<br />

793865<br />

Pregnancy<br />

CNS Schizophrenia<br />

Musculo-skeletal Orthopedics<br />

Cancer Breast<br />

Obstetrics/ gynecology<br />

Gynecology<br />

CNS Neuropathy<br />

Genitourinary Renal<br />

Cancer Colorectal, liver,<br />

pancreas<br />

CV / cardiology Cholesteremia,<br />

atherosclerosis,<br />

myocardial infarction


130<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Gleave,<br />

Martin<br />

Goetz,<br />

Thomas<br />

Goldenberg,<br />

Larry<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

Orthopedics Medicine UBC Providence Health Care Research<br />

Institute<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

gleave@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=63578&_<br />

Type=Researchers-Data-<br />

base&_Title=Gleave-Dr.-<br />

Martin-E.<br />

goetz@vbjc.ca http://www.orthosurgery.<br />

ubc.ca/faculty_bios/<br />

goetz.html<br />

research@vanhosp.bc.ca http://www.prostatecentre.com/aboutus/aboutus.<br />

phppageID=118<br />

Goldman, Ran Pediatrics UBC Child & Family Research Institute rgoldman@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=273<br />

Goncalves,<br />

Jose<br />

Gordon,<br />

Wendy<br />

Goumeniouk,<br />

Alex<strong>and</strong>er P.<br />

N/A N/A Obstetrics & gynecology<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Interior Health Authority-Penticton<br />

Regional Hospital<br />

Genitourinary, cancer Prostate<br />

Musculo-skeletal Orthopedics<br />

Cancer, genitourinary Prostate<br />

Emergency medicine Pediatrics<br />

Fraser Health N/A N/A CV / cardiology<br />

Medicine UBC UBC Campus dooley@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=282<br />

399151<br />

Grafstein, Eric Surgery UBC Providence Health Care Research<br />

Institute<br />

Gray, James Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Greidanus,<br />

Nelson<br />

Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

egrafstein@providencehealth.bc.ca<br />

http://www.sphemerg.ca/<br />

research/grafstein<br />

allgray@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=288<br />

548071<br />

Nelson.greidanus@vch.ca http://www.orthosurgery.<br />

ubc.ca/faculty_bios/<br />

greidanus.html<br />

CNS Bipolar<br />

ID/ infection, emergency<br />

medicine<br />

Hepatitis<br />

Gastro-intestinal Colitis, esophageal/<br />

stomach<br />

Musculo-skeletal Orthopedics


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

131<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Gross,<br />

Katherine<br />

Guns, Emma<br />

S.<br />

Urologic <strong>Sciences</strong><br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Interior Health Authority-Penticton<br />

Regional Hospital<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

N/A N/A Autoimmune Arthritis<br />

emma.guns@vch.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=80657&_<br />

Type=Researchers-<br />

Database&_Title=Guns-<br />

Dr.-Emma-S.<br />

Gurjal, A B.C. Cancer Agency N/A http://surrey-bc.cofars.ca/<br />

dr-gurjal-anagha/93367/<br />

Hall, Wendy Nursing Applied<br />

Science<br />

Halperin,<br />

Frank<br />

Halperin,<br />

Ross<br />

Hamburger,<br />

Jaap<br />

UBC UBC Campus wendy.hall@nursing.ubc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=373<br />

Medicine Medicine UBC Interior Health Authority-Kelowna<br />

General Hospital<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute, Van Coastal Health<br />

Research Institute<br />

Hameed, M. Interior Health Authority-Royal<br />

Inl<strong>and</strong> Hospital/ Kelowna General<br />

Hospital<br />

N/A www.directory.ubc.ca/<br />

index.cfm<br />

Cancer Prostate<br />

Cancer Colorectal<br />

CNS Cognitive<br />

CV / cardiology Heart failure, acute<br />

coronary syndrome<br />

B.C. Cancer Agency rhalperin@bcancer.bc.ca N/A Cancer Prostate<br />

hamburge@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=65361&_<br />

Type=Researchers-Data-<br />

base&_Title=Hamburger-<br />

Dr.-Jaap-N.<br />

N/A N/A Critical care<br />

CV / cardiology Atherosclerosis,<br />

coronary disease<br />

Harder, Curtis Van Isl<strong>and</strong> Health Authority curtis.harder@viha.ca N/A ID/ infection Microbiology,<br />

pharmacy<br />

Harris, Devin Medicine Medicine UBC Providence Health Care Research<br />

Institute, Van Coastal Health<br />

Research Institute<br />

N/A http://www.sphemerg.ca/<br />

research/harris<br />

CV / cardiology,<br />

emergency medicine<br />

Myocardial infarction


132<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Hashimoto,<br />

Stanley<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

hashist@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=317<br />

294272<br />

CNS MS<br />

Havelock, Jon Fraser Health N/A N/A Obstetrics / gynecology<br />

Hawley,<br />

Philippa<br />

General Internal<br />

Medicine<br />

Medicine UBC B.C. Cancer Agency phawley@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001174<br />

Obstetrics<br />

Cancer Palliative care<br />

Hayashi, A Van Isl<strong>and</strong> Health Authority N/A N/A Surgery Pediatrics<br />

CNS Huntingdon’s<br />

Hayden,<br />

Michael<br />

Hayden,<br />

Robert<br />

Henderson,<br />

Mark<br />

Henderson,<br />

William<br />

Heywood, M Obstetrics &<br />

Gynecology<br />

Hill, John Pathology &<br />

Laboratory<br />

Med<br />

Hilton,<br />

Donald<br />

CMMT Medicine UBC Child & Family Research Institute mrh@cmmt.ubc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=54<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute/ Fraser Health<br />

Fraser Health N/A N/A CV / cardiology Cardiology<br />

Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

william.henderson@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

011369<br />

Medicine UBC B.C. Cancer Agency mheywood@bccancer.bc.ca http://www.bccancer.bc.ca/HPI/SON/<br />

Council/members/<br />

Dr.+Mark+Heywood.htm<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Van Isl<strong>and</strong> Health Authority -<br />

Cowichan District Hospital<br />

jshill@interchange.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_john_<br />

hill.shtml<br />

Critical care Inflammatory,<br />

trauma<br />

Cancer Urogenital<br />

CV / cardiology Coronary disease<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

133<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Ho, Cheryl Medicine Medicine UBC B.C. Cancer Agency cho@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

014081<br />

Cancer Lung<br />

Ho, Kennely Fraser Health N/A N/A CNS Stroke<br />

Dermatology Psoriasis<br />

Ho, Vincent Medicine/<br />

Dermatology &<br />

Skin Science<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Hogg, James iCAPTURE Medicine UBC Providence Health Care Research<br />

Institute<br />

Medicine UBC/ SFU Providence Health Care Research<br />

Institute<br />

Hogge, Donna Medicine Medicine UBC Van Coastal Health Research<br />

Institute/ B.C. Cancer Agency<br />

Hohl, Corinne<br />

M.<br />

Holl<strong>and</strong>,<br />

Simon<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

Hogg, Robert Population &<br />

Public Health/<br />

Health <strong>Sciences</strong><br />

Ophthalmology<br />

& Visual<br />

Science<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

vho@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=66518&_<br />

Type=Researchers-<br />

Database&_Title=Ho-<br />

Dr.-Vincent-C; http://<br />

www.skincarecentre.ca/<br />

about_us/doctors/vincent_ho.htm<br />

jhogg@mrl.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_jim_<br />

hogg.shtml<br />

robert_hogg@sfu.ca www.fhs.sfu.ca/portal_<br />

memberdata/rhogg<br />

dhogge@bccancer.bc.ca http://www.bccrc.ca/tfl/<br />

people_dhogge.html<br />

chohl@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage<br />

=personDetail&row=<br />

1000014576 http://<br />

www.vchri.ca/s/<br />

IIFL_InvestigatorAbstracts.<br />

aspReportID=124905<br />

simon_holl<strong>and</strong>@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=340<br />

813891<br />

Pulmonary COPD<br />

ID/ infection HIV/AIDS<br />

Cancer Leukemia<br />

CNS, emergency<br />

medicine<br />

Drug abuse<br />

Ophthalmology Transplant


134<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Holmes-<br />

Boulton,C.<br />

Honer,<br />

William<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

Hooge, John Neurology Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Interior Health Authority N/A N/A Critical care<br />

honer@interchange.ubc.ca http://www.neuroscience.<br />

ubc.ca/honer.htm<br />

CNS Psychosis<br />

jphooge@telus.net N/A CNS MS<br />

Horgan, K Van Isl<strong>and</strong> Health Authority N/A N/A Genitourinary Nephrology<br />

Hoskins, Paul Medicine Medicine UBC B.C. Cancer Agency phoskins@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=345<br />

271858<br />

Houghton,<br />

Kristin<br />

Pediatrics Medicine UBC Child & Family Research Institute khoughton@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=286<br />

Cancer Urogenital, lymphoma<br />

Autoimmune Arthritis<br />

Hrebicek, O Van Isl<strong>and</strong> Health Authority N/A N/A CNS Neurology<br />

Hsiang, York Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

Hsiung, Ging<br />

Yeuk [Robin]<br />

Hu, Joan Statistics &<br />

Actuarial Science<br />

Hukin,<br />

Juliette<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

yhsiang@vanhosp.bc.ca http://www.surgery.ubc.<br />

ca/faculty/yhsiang.html<br />

hsiung@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012208<br />

SFU joanh@stat.sfu.ca http://www.stat.sfu.<br />

ca/~joanh/<br />

Pediatrics Medicine UBC Child & Family Research Institute jhukin@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=58<br />

CV / cardiology Cardiovascular<br />

disease<br />

CNS Alzheimer’s<br />

ID/ infection, other HIV<br />

Cancer Brain/CNS


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

135<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Human,<br />

Derek<br />

Hurley, R.<br />

Morrison<br />

Ignaszewski,<br />

Andrew<br />

Imai, Pauline<br />

H.<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute dhuman@cw.bc.ca http://www.bcchildrens.<br />

ca/Services/ChildrensHeartCentre/Healthcareteam/Leadershipteam.<br />

htm#human<br />

Pediatrics Medicine UBC Child & Family Research Institute mhurley@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

753869<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Oral Biological<br />

& Medical SCI<br />

aignaszewski@providencehealth.bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751017<br />

Dentistry UBC UBC Campus pauline.imai@hotmail.com https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

011342<br />

Imrie, John Van Coastal Health-Lion's Gate<br />

Hospital<br />

CV / cardiology Coronary disease<br />

Transplant GVHD<br />

CV/ cardiology,<br />

transplant<br />

Dental Hygiene<br />

Congestive heart<br />

failure, coronary<br />

disease<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

Innis, Sheila Pediatrics Medicine UBC Child & Family Research Institute sinnis@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=61<br />

CNS, pulmonary Development, cystic<br />

fibrosis<br />

Jackson, ML Van Isl<strong>and</strong> Health Authority N/A N/A Ophthalmology<br />

Gastro-intestinal Crohn’s<br />

Jacobson,<br />

Kevan<br />

Jacova,<br />

Claudia<br />

Pediatrics Medicine UBC Child & Family Research Institute kjacobson@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=62<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

claudija@interchange.<br />

ubc.ca<br />

http://ubcneurology.com/<br />

Staff%20Web%20Pages/<br />

CJacova.html<br />

CNS Alzheimer’s


136<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Jamieson, Eric<br />

W.R.<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute/ Providence Health Care<br />

Research Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

eric.jamieson@ubc.ca http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

Jan, James Pediatrics Medicine UBC Child & Family Research Institute jjan@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

search_results.asp<br />

Janssen,<br />

Patricia<br />

Population &<br />

Public Health<br />

Medicine UBC Child & Family Research Institute pjanssen@interchange.<br />

ubc.ca<br />

http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=343<br />

CV / cardiology Cardiac surgery, cardiovascular<br />

disease,<br />

coronary bypass<br />

CNS FASD<br />

CNS Health<br />

Jasas, K B.C. Cancer Agency N/A N/A Cancer Lung<br />

jjastrze@vanhosp.bc.ca N/A Genitourinary Renal<br />

Jastrzebski,<br />

Jacek<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Javer, Amin Surgery Medicine UBC Providence Health Care Research<br />

Institute<br />

Javidan,<br />

Manouchehr<br />

Joffres,<br />

Michel<br />

Johnston,<br />

Dean<br />

Neurology Medicine UBC Van Coastal Health Research<br />

Institute<br />

Health <strong>Sciences</strong><br />

sinussurgeon@drjaver.com http://www.surgery.ubc.<br />

ca/faculty/ajaver.html<br />

manouchehr.javidan@vch.ca http://vch.eduhealth.ca/<br />

PDFs/FM/FM.470.V279.pdf<br />

SFU mjoffres@sfu.ca www.fhs.sfu.ca/portal_<br />

memberdata/mjoffres<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

dccj@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001176<br />

Surgery Polyps<br />

CNS Epilepsy/ seizures<br />

ID/ infection HIV<br />

CV / cardiology Atherosclerosis<br />

Jones, C Van Isl<strong>and</strong> Health Authority N/A N/A Genitourinary Nephrology<br />

CNS Epilepsy/ seizures<br />

Jones,<br />

Michael<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Jue, John C. Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

michael.jones@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=381<br />

089317<br />

jjue@unixg.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=383<br />

395162<br />

CV / cardiology Coronary disease


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

137<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Jung, Beverly Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Karim,<br />

Mohamud<br />

Karim,<br />

Shahzad<br />

Kastrukoff,<br />

Lorne<br />

Surgery Medicine UBC Providence Health Care Research<br />

Institute/ Fraser Health<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

bjung@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

006604<br />

Genitourinary Renal<br />

Fraser Health N/A N/A Genitourinary Renal<br />

Shahzadk@shaw.ca http://www.surgery.ubc.<br />

ca/faculty/skarim.html<br />

lornefk@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=p<br />

ersonDetail&row=390158<br />

974 http://www.chromos.<br />

com/about/exec/lornekastrukoff.htm<br />

Keenan, Sean Medicine Medicine UBC Fraser Health sean_keenan@telus.net http://f1000medicine.com/<br />

member/2058229206155046<br />

CV / cardiology Coronary disease<br />

CNS MS, brain injury<br />

Critical care Septic shock, sepsis<br />

Kelsall, John T Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Kennecke,<br />

Hagan<br />

jkelsall@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

752758<br />

Medicine Medicine UBC B.C. Cancer Agency hkennecke@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012828<br />

Keown, Paul Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Kerns,<br />

Kimberly A<br />

keown@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=66522&_<br />

Type=Researchers-<br />

Database&_Title=Keown-<br />

Dr.-Paul-A.<br />

Psychology UVic kkerns@uvic.ca http://web.uvic.ca/psyc/<br />

kerns.html<br />

Autoimmune Arthritis<br />

Cancer Gastro-intestinal,<br />

breast<br />

Transplant, genitourinary<br />

Renal<br />

CNS FASD


138<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Kerr, Charles Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Khalil,<br />

Nasreen<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

ckerr@providencehealth.<br />

bc.ca<br />

http://www.providenceresearch.ca/directory/<br />

ResearcherDetail.aspx<br />

nkhalil@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=74097&_<br />

Type=Researchers-<br />

Database&_Title=Khalil-<br />

Dr.-Nasreen<br />

Khoo, Kong Medicine Medicine UBC B.C. Cancer Agency kkhoo@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=398<br />

152570<br />

Kiaii,<br />

Mercedeh<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

mkiaii@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

003484<br />

CV / cardiology Coronary disease<br />

Pulmonary Fibrosis<br />

Cancer Brain/CNS<br />

Hematology Thrombosis/ coagulation,<br />

anemia<br />

Kibsey, P Van Isl<strong>and</strong> Health Authority N/A N/A ID/ infection Microbiology<br />

Kiess, Marla Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

mkiess@providencehealth.<br />

bc.ca<br />

http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

Kim, David B.C. Cancer Agency dkim@bccancer.bc.ca http://kelowna-bc.cofars.<br />

ca/dr-kim-david/100214/<br />

Kinahan,T. Interior Health Authority-Kelowna<br />

General Hospital<br />

CV / cardiology Hypertension<br />

Cancer Prostate<br />

N/A N/A Cancer Bladder<br />

Kirk, P Van Isl<strong>and</strong> Health Authority N/A N/A Other Palliative care<br />

CNS Mental health<br />

Kjernisted,<br />

Kevin<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

kevin.kjernisted@ubc.ca http://www.copemanhealthcare.com/medicalstaff/dr.-kevin-kjernistedmd-frcpc<br />

Klasa, Richard Medicine Medicine UBC B.C. Cancer Agency rklasa@bccancer.bc.ca http://www.bccrc.ca/at/<br />

people_rklasa.html<br />

Cancer Lymphoma


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

139<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Klimo, Paul Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Knight, Darryl Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Knowling,<br />

Meg<br />

dknight@mrl.ubc.ca http://www.icapture.<br />

ubc.ca/who/who_darryl_knight.shtml<br />

Kollmannsberger,<br />

Christian<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

pklimo@direct.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=408<br />

913180<br />

Medicine Medicine UBC B.C. Cancer Agency mknowling@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=411<br />

680194<br />

B.C. Cancer Agency ckollmannsberger@bccancer.bc.ca<br />

http://www.bccrc.ca/at/<br />

people_ckollmannsberger.<br />

html<br />

Cancer Breast, colorectal<br />

Pulmonary Asthma<br />

Cancer Gastro-intestinal<br />

Cancer, genitourinary Colorectal, kidney,<br />

gastro-intestinal,<br />

urogenital, liver<br />

Kooy, J. Interior Health Authority N/A N/A CNS Alzheimer's<br />

Kornder, Jan Fraser Health-Surrey Memorial<br />

Hospital<br />

Krajden, Mel <strong>Clinical</strong> <strong>Trials</strong> Medicine UBC Provincial Health Services<br />

Authority Labs<br />

Krieger,<br />

Charles<br />

Kuritzky,<br />

Robin<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Kwan, Peter Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Jan.Kornder@fraserhealth.<br />

ca<br />

mel.krajden@bccdc.ca www.cdc.ubc.ca/People/<br />

MelKrajden.htm<br />

N/A https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=419<br />

827513<br />

N/A CV / cardiology Acute coronary<br />

syndrome<br />

ID/ infection HPV<br />

CNS ALS<br />

Fraser Health N/A N/A CV / cardiology Coronary disease<br />

pwkwan@gmail.com https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=424<br />

131757<br />

ID/ infection HPV<br />

Kwan, Susan Fraser Health N/A N/A CV/ cardiology,<br />

metabolic/ endocrine<br />

Kwan, Winkle Medicine Medicine UBC B.C. Cancer Agency N/A http://www.surgery.ubc.<br />

ca/faculty/wkwan.html<br />

Cancer Prostate<br />

Cardiology, diabetes


140<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Kwon, Brian Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

Kwon, Janice Obstetrics &<br />

Gynecology<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC B.C. Cancer Agency / Van Coastal<br />

Health Research Institute<br />

Lai, Kevin Van Isl<strong>and</strong> Health Authority-<br />

Nanaimo Regional General<br />

Hospital<br />

Lakhani,<br />

Anisha<br />

brian.kwon@vch.ca http://www.orthosurgery.<br />

ubc.ca/faculty_bios/kwon.<br />

html<br />

N/A www.powerstudy.ca/<br />

profile/janice-kwon<br />

CNS Neuropathy<br />

Cancer Cervical, endometrial,<br />

gynecology<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

Fraser Health N/A N/A ID/ infection<br />

Lam, George Fraser Health N/A N/A Genitourinary Nephrology<br />

CNS Depression<br />

Lam,<br />

Raymond<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

Lam, Stephen Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Lam, Wendy Oncology/<br />

Hematology<br />

Laskin,<br />

Janessa<br />

Lauder,<br />

Gillian<br />

r.lam@ubc.ca http://www.crestbd.ca/<br />

researchers/lam-raymond.<br />

php<br />

slam2@bccancer.bc.ca www.bccancerfoundation.<br />

com/cms/page1396.cfm;<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=69170&_<br />

Type=Researchers-<br />

Database&_Title=Lam-<br />

Dr.-Stephen-C.<br />

Pulmonary Asthma<br />

Fraser Health-Burnaby Hospital wylam@telus.net N/A Cancer, hematology Multiple myeloma,<br />

metastatic, breast,<br />

lung, idiopathic<br />

thrombocytic<br />

purpura<br />

Medicine Medicine UBC B.C. Cancer Agency jlaskin@bccancer.bc.ca http://www.bccrc.ca/at/<br />

people_jlaskin.html<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

UBC Child & Family Research Institute glauder@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=284<br />

Cancer Lung<br />

Anesthesiology Pediatrics


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

141<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Lavoie, Julye B.C. Cancer Agency jlavoie@bccancer.bc.ca N/A ID/ infection CMV<br />

Lawson,<br />

Fraser Health N/A N/A Pulmonary Asthma<br />

Edward<br />

Lawson,<br />

Lindsay<br />

Respiratory<br />

Medicine<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

llawson@providencehealth.<br />

bc.ca<br />

www.pacificlung.com/<br />

who_we_are.php<br />

Le, Lyly Medicine Medicine UBC B.C. Cancer Agency lle@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

010825<br />

Lear, Scott Biomedical<br />

Physiology<br />

SFU Providence Health Care Research<br />

Institute<br />

salear@sfu.ca; slear@<br />

providencehealth.bc.ca<br />

www2.fas.sfu.ca/kin/Faculty.html;<br />

http://www.<br />

cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=281<br />

Leavitt, Blair CMMT Medicine UBC Child & Family Research Institute bleavitt@cmmt.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=40908&_<br />

Type=Researchers-<br />

Database&_Title=Leavitt-<br />

Dr.-Blair-R.<br />

Lee, Chong Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Lee,<br />

Christopher<br />

Pulmonary Asthma, complications<br />

of HIV<br />

Cancer Colorectal, pancreas,<br />

prostate<br />

Metabolic/ endocrine,<br />

CV/ cardiology<br />

Metabolic/ endocrine,<br />

CV/ cardiology<br />

Obesity, coronary<br />

disease<br />

Genetic disease,<br />

coronary disease<br />

N/A N/A CNS Parkinson’s<br />

Medicine Medicine UBC B.C. Cancer Agency clee@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

753751<br />

Lee, Ursula Medicine Medicine UBC B.C. Cancer Agency ulee@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751018<br />

Leger,<br />

Chantal S.<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Cancer Lung, MDR, melanoma<br />

cleger@providencehematology.com<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012133<br />

Cancer Urogenital<br />

Cancer Leukemia, lymphoma


142<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Leitch,<br />

Heather<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Leith, Jordan Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

hleitch@providencehematology.com<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012134<br />

jmleith@interchange.ubc.ca http://www.orthosurgery.<br />

ubc.ca/faculty_bios/leith.<br />

html<br />

Hematology, cancer Leukemia, myeloma<br />

Musculo-skeletal Orthopedics<br />

Lerch, L Van Isl<strong>and</strong> Health Authority N/A N/A Surgery Surgery<br />

Leung, A. Interior Health Authority-Royal Inl<strong>and</strong> Hospital<br />

N/A N/A Metabolic/ endocrine Diabetes<br />

Genitourinary Dialysis, renal<br />

Levin, Adeera Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Levy, Robert Medicine Medicine UBC Providence Health Care Research<br />

Institute/ Van Coastal Health<br />

Research Institute<br />

Lichtenstein,<br />

Samuel<br />

Lillquist,<br />

Yol<strong>and</strong>a<br />

Cardiovascular<br />

Surgery<br />

Surgery UBC Providence Health Care Research<br />

Institute<br />

alevin@providencehealth.<br />

bc.ca<br />

rlevy@providencehealth.<br />

bc.ca<br />

http://www.icapture.<br />

ubc.ca/who/who_robert_Levy.shtml<br />

slichtenstein@providencehealth.bc.ca<br />

http://www.krescent.ca/<br />

Page.aspxpid=755<br />

www.ctsnet.org/home/<br />

slichtenstein<br />

Pediatrics Medicine UBC Child & Family Research Institute ylillquist@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

753873<br />

Lim, Howard B.C. Cancer Agency N/A N/A Cancer<br />

Lim, Ken Medicine UBC Child & Family Research Institute klim@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=78<br />

Liston, Rob Obstetrics &<br />

Gynecology<br />

UBC Child & Family Research Institute rliston@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=79<br />

Pulmonary COPD, fibrosis,<br />

hypertension<br />

CV / cardiology Surgery<br />

Pulmonary Cystic fibrosis<br />

Neonatology Cardiology, pregnancy<br />

Obstetrics & gynecology<br />

Pregnancy


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

143<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Lohrisch,<br />

Caroline<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine Medicine UBC B.C. Cancer Agency N/A https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012184<br />

Lu, Shao-Hua Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

Lui, Harvey Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Ma, Patrick E Ophthalmology<br />

& Visual<br />

Science<br />

Maberley,<br />

David<br />

MacEntee,<br />

Michael<br />

MacEwan,<br />

William<br />

MacLean,<br />

Grant<br />

Macpherson,<br />

Nichol<br />

Ophthalmology<br />

& Visual<br />

Science<br />

Oral Health <strong>Sciences</strong><br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

shao.lu@ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

754182<br />

harvey.lui@ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=68599&_<br />

Type=Researchers-<br />

Database&_Title=Lui-Dr.-<br />

Harvey<br />

patma@interchange.ubc.ca;<br />

eyedoc.retina@shaw.ca<br />

Dentistry UBC UBC Campus macentee@interchange.<br />

ubc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=508<br />

833130<br />

david.maberley@vch.ca http://www.cmr.ubc.ca/<br />

david_maberley.html<br />

http://www.elders.<br />

dentistry.ubc.ca/research/<br />

our_people/macentee.asp<br />

Cancer Breast, gastrointestinal<br />

CNS Addiction<br />

Dermatology Psoriasis<br />

Ophthalmology Diabetes<br />

Ophthalmology AMD<br />

Dental Implants<br />

Fraser Health N/A N/A CNS Schizophrenia<br />

Medicine Medicine UBC B.C. Cancer Agency gmaclean@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

006599<br />

Medicine Medicine UBC B.C. Cancer Agency nmacpher@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001184<br />

Cancer Gastro-intestinal<br />

Cancer Breast, lymphoma


144<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Magee, Laura<br />

A.<br />

Obstetrics &<br />

Gynecology<br />

Maguire, John Pathology &<br />

Laboratory<br />

Med<br />

Man, Paul Respiratory<br />

Medicine<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Child & Family Research Institute lmagee@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=86<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Mancini, John Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Manyari,<br />

Dante<br />

Marquette,<br />

Gerald<br />

Obstetrics &<br />

Gynecology<br />

Marra, Carlo Pharmaceutical<br />

<strong>Sciences</strong><br />

Marsden,<br />

Julian<br />

john.maguire@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751645<br />

pman@providencehealth.<br />

bc.ca<br />

mancini@interchange.<br />

ubc.ca<br />

www.pacificlung.com/<br />

who_we_are.php<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=63568&_<br />

Type=Researchers-Data-<br />

base&_Title=Mancini-Dr.-<br />

G.B.-John<br />

Obstetrics / gynecology<br />

Pregnancy<br />

Cancer Brain/CNS<br />

Pulmonary COPD<br />

CV / cardiology Cardiovascular<br />

disease<br />

Fraser Health N/A N/A CV / cardiology Coronary disease<br />

Medicine UBC Child & Family Research Institute gmarquette@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001292<br />

UBC Van Coastal Health Research<br />

Institute<br />

Carlo.marra@ubc.ca www.pharmacy.ubc.ca/<br />

faculty_staff/faculty/<br />

practice/practice_carlo_<br />

marra.html<br />

Family Practice Medicine UBC UBC Campus N/A http://www.bcpsqc.ca/<br />

celebrating-achievementsin-bc/BCPSQC_Celebrating_Achievements_Marsden.htm<br />

Obstetrics / gynecology<br />

Autoimmune, dermatology,<br />

other<br />

Pregnancy<br />

Arthritis, psoriasis<br />

CV / cardiology Congestive heart<br />

failure


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

145<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Martin, Lee<br />

Ann<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine Medicine UBC B.C. Cancer Agency lmartin@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001188<br />

Martin, Mike Radiology Medicine UBC Van Coastal Health Research<br />

Institute<br />

m.l.martin@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

754357<br />

Martins, Heidi Medicine Medicine UBC B.C. Cancer Agency hmartins@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

002805<br />

Matsell,<br />

Douglas<br />

Matsuda-<br />

Abedini, Mina<br />

Maung, Tun<br />

Zan<br />

Mayer,<br />

Chantel<br />

Pediatrics Medicine UBC Child & Family Research Institute dmatsell@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=89<br />

Pediatrics Medicine UBC Child & Family Research Institute mmatsuda@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012350<br />

Cancer Breast<br />

CV / cardiology Cardiovascular<br />

disease<br />

Cancer Urogenital, kidney,<br />

lung<br />

Metabolic/ endocrine Growth<br />

Transplant, genitourinary<br />

Fraser Health N/A N/A CV / cardiology Cardiology<br />

Pediatrics Medicine UBC Child & Family Research Institute N/A N/A Neonatology Neonatology<br />

McCauley, G. Interior Health Authority-Kelowna<br />

General Hospital<br />

McCormack,<br />

Robert<br />

McDermid,<br />

Kevin<br />

McElhaney,<br />

Janet<br />

Renal<br />

N/A N/A Pulmonary COPD<br />

UBC Fraser Health N/A N/A Musculo-skeletal Orthopedics<br />

Fraser Health-Langley Memorial<br />

Hospital<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

janet.mcelhaney@ubc.ca http://www.ID.med.ubc.<br />

ca/Faculty/Associate_<br />

Members/Janet_McElhaney.htm<br />

ID/ infection Herpes, respiratory


146<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

McIntosh,<br />

Diane<br />

McKenzie,<br />

Donald<br />

McKeown,<br />

Martin J.<br />

McManus,<br />

Bruce<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

diane.mcintosh@ubc.ca http://www.copemanhealthcare.com/medicalstaff/dr.-diane-mcintoshmd-frcpc<br />

Family Practice Medicine UBC UBC Campus kari@interchange.ubc.ca http://www.hkin.educ.<br />

ubc.ca/faculty/mckenzied/<br />

mckenzied.htm<br />

Neurology Medicine UBC Van Coastal Health Research<br />

Institute<br />

Pathology &<br />

Laboratory<br />

Med<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

mmckeown@interchange.<br />

ubc.ca<br />

www.parkinsons.ubc.<br />

ca/Dr.MartinJ.McKeown.<br />

htm#Research<br />

bmcmanus@mrl.ubc.ca http://www.icapture.<br />

ubc.ca/who/who_bios_<br />

bruce_mcmanus.shtml<br />

Meneilly,<br />

Graydon<br />

Merchant,<br />

Richard<br />

Merkur,<br />

Andrew<br />

Metzger,<br />

Daniel<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Melosky, Barb Medicine Medicine UBC B.C. Cancer Agency bmelosky@bccancer.bc.ca http://www.eventcare.<br />

ca/clients/cowc/bios/barbara_melosky.html<br />

Ophthalmology<br />

& Visual<br />

Science<br />

Fraser Health - Royal Columbian<br />

Hospital<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

graydon.meneilly@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

008929<br />

CNS Mental health<br />

Cancer Breast<br />

N/A N/A Anesthesiology<br />

amerkur@yahoo.com https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

015262<br />

Pediatrics Medicine UBC Child & Family Research Institute dmetzger@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=91<br />

Michels, Jorg B.C. Cancer Agency jmichels@bccancer.bc.ca http://www.bccrc.ca/drc/<br />

people_jmichels.html<br />

CNS Parkinson’s<br />

CV / cardiology Cardiovascular<br />

disease<br />

Cancer Gastro-intestinal,<br />

lung<br />

Metabolic/ endocrine Diabetes<br />

Ophthalmology AMD<br />

Metabolic/ endocrine Diabetes<br />

Cancer Urogenital


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

147<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Mikelberg,<br />

Frederick<br />

Ophthalmology<br />

& Visual<br />

Science<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

fsm@interchange.ubc.ca<br />

frederick.mikelberg@vch.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=36610&_<br />

Type=Researchers-Data-<br />

base&_Title=Mikelberg-<br />

Dr.-Frederick-S.<br />

Ophthalmology Glaucoma<br />

Miller, D Van Isl<strong>and</strong> Health Authority N/A N/A Metabolic/ endocrine Endocrinology<br />

Miller, Dianne Obstetrics &<br />

Gynecology<br />

Mirch<strong>and</strong>ani,<br />

D.<br />

Mirzanejad,<br />

Yazdan<br />

Medicine UBC BCCA/ Van Coastal Health<br />

Research Institute<br />

Interior Health Authority-Penticton<br />

Regional Hospital<br />

Misri, Shaila Psychiatry Medicine UBC Women's Health Research Institute/<br />

Child & Family Research<br />

Institute<br />

Mohamed,<br />

Islam<br />

Money,<br />

Deborah<br />

Montaner,<br />

Julio<br />

Montessori,<br />

Valentina<br />

Morris,<br />

Dorothy<br />

Obstetrics &<br />

Gynecology<br />

dmiller@bccancer.bc.ca www.obstgyn.ca/About/<br />

DivisionGyneOnc.html<br />

Cancer Cervical, endometrial,<br />

gynecology<br />

N/A N/A Cancer Breast<br />

Fraser Health N/A N/A ID/ infection,<br />

metabolic<br />

B.C. Cancer Agency/ Interior<br />

Health Authority-Kelowna General<br />

Hospital<br />

Medicine UBC Women's Health Research<br />

Institute<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Moss, Robert Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

shaila.misri@ubc.ca;<br />

smisri@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=546<br />

802711<br />

Diarrhea, diabetes<br />

CNS Depression<br />

imohamed@bccancer.bc.ca N/A Cancer Lung<br />

dmoney@cw.bc.ca http://www.whri.org/<br />

projects<strong>and</strong>people/<br />

people/Money.htm<br />

jmontaner@cfenet.ubc.ca http://www.cmeonhiv.<br />

com/pub/dr..julio.montaner.php<br />

vmontessori@cfenet.ubc.ca http://www.cmeonhiv.<br />

com/pub/dr..valentina.<br />

montessori.php<br />

ID/ infection, obstetrics<br />

/ gynecology<br />

ID/ infection HIV<br />

ID/ infection HIV<br />

Van Isl<strong>and</strong> Health Authority dorothy.morris@viha.ca N/A CV / cardiology<br />

rmoss@providenceheallth.<br />

bc.ca<br />

www.heartcentre.ca/<br />

pop_up_RMoss.asp<br />

HPV, pregnancy<br />

CV / cardiology Transplant


148<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Murray, Nevin Medicine Medicine UBC B.C. Cancer Agency nmurray@bccancer.bc.ca http://www.bccrc.ca/at/<br />

people_nmurray.html<br />

Nadel, Helen Radiology Medicine UBC Child & Family Research Institute hnadel@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=570<br />

168607<br />

Nakielna,<br />

Barbara<br />

Respiratory<br />

Medicine<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Naude, J. Interior Health Authority-Penticton<br />

Regional Hospital<br />

Nelems, B. Interior Health Authority-Kelowna<br />

General Hospital<br />

Nevill,<br />

Thomas<br />

Newby,<br />

Br<strong>and</strong>i<br />

Nguan, Chris Urologic <strong>Sciences</strong><br />

Nigro, Mark Urologic <strong>Sciences</strong><br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

bnakielna@providencehealth.bc.ca<br />

www.pacificlung.com/<br />

who_we_are.php<br />

Cancer Lung<br />

CV / cardiology Coronary disease<br />

Pulmonary Cystic fibrosis<br />

N/A N/A Musculo-skeletal Orthopedics<br />

N/A N/A Cancer Lung<br />

tnevill@bccancer.bc.ca http://www.canadianhematologysociety.org/<br />

exec_tomnevill.htm<br />

Cancer, hematology Leukemia, thrombocytopenia<br />

Fraser Health N/A N/A CNS Pain<br />

chris@nguan.ca www.med.ubc.ca/research/rm/rm_urologic.<br />

htm<br />

Genitourinary Transplant<br />

Medicine UBC Van Coastal Health Res Inst nigro@interchange.ubc.ca N/A Genitourinary Bladder<br />

Nixon, Alan Fraser Health N/A N/A CNS Pain<br />

Noble,<br />

Fraser Health N/A N/A Cancer Various<br />

Michael<br />

Norris, B B.C. Cancer Agency N/A N/A Cancer Breast<br />

Novak, D. Interior Health Authority-Penticton<br />

Regional Hospital<br />

N/A N/A CNS Stroke<br />

Musculo-skeletal Orthopedics<br />

O'Brien, Peter<br />

J.<br />

Orthopedics Medicine UBC UBC Campus pjobrien@interchange.<br />

ubc.ca<br />

http://www.orthosurgery.<br />

ubc.ca/faculty_bios/<br />

obrien.html


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

149<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Ochnio, Jan Pediatrics Medicine UBC Child & Family Research Institute jochnio@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

754518<br />

Offer, Robert Rheumatology Medicine UBC Interior Health Authority-Penticton<br />

Regional Hospital<br />

Oger, Joel Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Ong, May Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

O'Reilly,<br />

Susan<br />

Orenstein<br />

Lyall, Teddi<br />

Lynn<br />

Orrom,<br />

William<br />

Osiovich,<br />

Horacio<br />

roffer@shaw.ca www.directory.ubc.ca/<br />

index.cfm<br />

joel.oger@ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=58855&_<br />

Type=Researchers-<br />

Database&_Title=Oger-<br />

Dr.-Joel-J-F<br />

dr.ong@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=59768<br />

5024aspx<br />

Medicine UBC B.C. Cancer Agency SOReilly@bccancer.bc.ca www.bccrc.ca/at/people_<br />

soreilly.html<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Van Isl<strong>and</strong> Health Authority Canada. truenorth222@<br />

yahoo.com<br />

ID/ infection Hepatitis<br />

Autoimmune Arthritis<br />

CNS MS<br />

CNS Pain<br />

Cancer<br />

Orenstein@telus.net N/A CV / cardiology Acute coronary<br />

syndrome<br />

Pediatrics Medicine UBC Child & Family Research Institute hosiovich@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012356<br />

Ostrow, David Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Pai, Howard Health Information<br />

Science<br />

ostrow@telus.net; david.<br />

ostrow@vch.ca<br />

UVic B.C. Cancer Agency hpai@uvic.ca; hpai@<br />

bccancer.bc.ca<br />

N/A Surgery Surgery<br />

http://www.vch.ca/<br />

about_us/leadership/<br />

senior_executive_team/<br />

dr._david_n._ostrow<br />

http://hinf.uvic.ca/people/<br />

Pai.php<br />

Neonatology Neonatology<br />

Pulmonary Hypertension<br />

Cancer Brain/CNS


150<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Panagiotopoulos,<br />

Dina<br />

Pansegrau,<br />

Gary<br />

Papp,<br />

Anthony<br />

Paré, Peter Medicine &<br />

Pathology<br />

Paterson,<br />

Ryan<br />

Pearce,<br />

Stephen, MD<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute dpanagiotopoulos@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=103<br />

Medicine Medicine UBC B.C. Cancer Agency gpansegrau@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

010826<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

anthony.papp@ubc.ca http://www.surgery.ubc.<br />

ca/faculty/apapp.html<br />

ppare@mrl.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_peter_pare.shtml<br />

paterson@interchange.<br />

ubc.ca<br />

Urologic <strong>Sciences</strong><br />

http://urology.ubc.ca/wpcontent/uploads/2007/02/<br />

paterson-ryan.pdf<br />

Metabolic/ endocrine Diabetes<br />

Cancer Breast<br />

ID/ infection Infection<br />

Pulmonary COPD<br />

Genitourinary Kidney, prostate<br />

Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

Penn, Andrew Van Isl<strong>and</strong> Health Authority karen.coles@viha.ca N/A CNS, CV/ cardiology Stroke, neurology<br />

Person, D Van Isl<strong>and</strong> Health Authority N/A N/A Gastro-intestinal<br />

ID/ infection Respiratory<br />

Petric, Martin Medicine UBC Provincial Health Services<br />

Authority Labs<br />

martin.petric@bccdc.ca http://www.cdc.ubc.ca/<br />

People/MartinPetric.htm<br />

Petrik, David B.C. Cancer Agency dpetrik@bccancer.bc.ca N/A Cancer Prostate<br />

Petrunia,<br />

Van Isl<strong>and</strong> Health Authority N/A N/A Gastro-intestinal<br />

Dennis<br />

Petty, Ross Pediatrics Medicine UBC Child & Family Research Institute rpetty@cw.bc.ca https://www.directory. ubc.ca/index.cfmpage=<br />

personDetail&row=627<br />

046117<br />

Autoimmune Rheumatology<br />

Gastro-intestinal Colitis<br />

Phang,<br />

Terence<br />

Surgery Medicine UBC Providence Health Care Research<br />

Institute<br />

tphang@providencehealth.<br />

bc.ca<br />

http://www.bccancer.<br />

bc.ca/NR/exeres/<br />

C5D9B877-6E87-456B-<br />

B5FA-CF9BEEFC863E.htm


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

151<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Phillips,<br />

Elizabeth<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Phillips, Peter Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

ephillips@cfenet.ubc.ca N/A ID/ infection HIV<br />

pphillips@cfenet.ubc.ca http://www.ID.med.ubc.<br />

ca/Faculty/Peter_Phillips.<br />

htm<br />

Pick, Neora Medicine Medicine UBC UBC Campus npick@cw.bc.ca http://www.whri.org/<br />

projects<strong>and</strong>people/<br />

people/Pick.htm<br />

Pickles, Tom Surgery Medicine UBC B.C. Cancer Agency N/A www.surgery.ubc.ca/<br />

faculty/tpickles.html<br />

Piper, HG UBC Van Isl<strong>and</strong> Health Authority hgpiper@interchange.<br />

ubc.ca<br />

Pisesky, W. Surgery Interior Health Authority-Kelowna<br />

General Hospital<br />

Pistawka, K. Interior Health Authority-Kelowna<br />

General Hospital<br />

ID/ infection HIV<br />

ID/ infection HIV<br />

Cancer Urological, radiotherapy<br />

N/A Surgery Surgery<br />

N/A N/A Musculo-skeletal,<br />

surgery<br />

Orthopedics<br />

N/A N/A CV / cardiology Atrial fibrillation<br />

Pluta, Henryk Fraser Health N/A N/A Gastro-intestinal Gastro-enterology<br />

Polasek, P. Cardiology Interior Health Authority-Kelowna<br />

General Hospital<br />

Polasek, Petr Interior Health Authority-Kelowna<br />

General Hospital<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome, atrial<br />

fibrillation<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

Popkin, JS Van Isl<strong>and</strong> Health Authority N/A N/A Pediatric<br />

Ophthalmology AMD<br />

Potter,<br />

Michael<br />

Power,<br />

Maryse<br />

Prendiville,<br />

Julie<br />

Ophthalmology<br />

& Visual<br />

Science<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

mpotter@eyecarecentre.org http://www.cmr.ubc.ca/<br />

michael_potter.html<br />

Medicine Medicine UBC B.C. Cancer Agency N/A http://www.leukemiabmtprogram.org/general_<br />

information/about_us/<br />

our_doctors/power.html<br />

Pediatrics Medicine UBC Child & Family Research Institute jprendiville@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=644<br />

724262<br />

ID/ infection Fungal<br />

Dermatology Psoriasis


152<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Prest, Marcia Fraser Health N/A N/A Gastro-intestinal Gastro-enterology<br />

Priestman, B.<br />

Anne<br />

Prior ,<br />

Jerilynn<br />

Endocrinology<br />

& Metabolism<br />

Puil, Ernie Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Putnins,<br />

Edward<br />

Rabkin,<br />

Simon<br />

Ramanathan,<br />

Krishnan<br />

Oral Biological<br />

& Medical SCI<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

jerilynn.prior@vch.ca www.cemcor.ubc.ca/<br />

about/staff#prior<br />

Medicine UBC UBC Campus puil@neuro.pharmacology.<br />

ubc.ca<br />

Obstetrics / gynecology<br />

N/A Anesthesiology<br />

Dentistry UBC UBC Campus putnins@interchange.ubc.ca http://www.dentistry.ubc.<br />

ca/research/PeriodontalBiology/putnins.asp<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

rabkin@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=43358&_<br />

Type=Researchers-Data-<br />

base&_Title=Rabkin-Dr.-<br />

Simon-W.<br />

kramanathan@providencehealth.bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

011039<br />

Rao, Sanjay Medicine Medicine UBC B.C. Cancer Agency srao@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012835<br />

Raval, Manoj<br />

J.<br />

Raymond,<br />

Lynn<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

mraval@providencehealth.<br />

bc.ca<br />

http://www.providencehealthcare.org/colorectalsurgery/Manoj-Raval.html<br />

lynnr@interchange.ubc.ca http://www.neuroscience.<br />

ubc.ca/raymond.htm<br />

Gynecology<br />

Dental Hygiene<br />

CV / cardiology Cholesteremia<br />

CV / cardiology Acute coronary<br />

syndrome<br />

Cancer Colorectal, lung,<br />

head/neck, melanoma,<br />

pancreas,<br />

prostate<br />

Gastro-intestinal Motility<br />

CNS Huntingdon’s


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

153<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Redekop,<br />

Gary<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

gary.redekop@ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=39893&_<br />

Type=Researchers-Data-<br />

base&_Title=Redekop-<br />

Dr.-Gary-J.<br />

CNS Neurosurgery, stroke<br />

Reed, Melanie B.C. Cancer Agency mreed@bccancer.bc.ca N/A Cancer Breast<br />

Reid, John Surgery Medicine UBC Providence Health Care Research Institute<br />

N/A N/A CV / cardiology Coronary disease<br />

Musculo-skeletal Scoliosis<br />

Reilly,<br />

Christopher<br />

Rekart,<br />

Michael<br />

Reynolds,<br />

Steven<br />

Orthopedics Medicine UBC Child & Family Research Institute creilly@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=108<br />

Centre for Disease<br />

Control<br />

Medicine UBC BC Centre for Disease Control michael.rekart@bccdc.ca http://www.cdc.ubc.ca/<br />

People/MichaelRekart.htm<br />

ID/ infection HIV<br />

Medicine Medicine UBC Fraser Health sreynolds.md@gmail.com N/A Critical care, ID/<br />

infection<br />

Ricci, Donald Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Rieckmann,<br />

Peter<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Rivers, Jason Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

ricci@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=66053&_<br />

Type=Researchers-<br />

Database&_Title=Ricci-<br />

Dr.-Donald-R.<br />

p.rieckmann@brain.ubc.ca http://www.ubcneurology.com/Staff%20Web%20<br />

Pages/PRieckmann.html<br />

N/A http://www.dermatology.<br />

ca/find_derm/profiles/<br />

jason_k_rivers.html<br />

Septic shock, ARDS<br />

CV / cardiology Acute coronary<br />

syndrome<br />

CNS MS<br />

Dermatology Inflammatory,<br />

psoriasis


154<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Road, Jeremy Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Robinow, R.<br />

Oliver<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

jroad@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=43383&_<br />

Type=Researchers-<br />

Database&_Title=Road-<br />

Dr.-Jeremy-D.<br />

richard.robinow@ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=678<br />

543322<br />

Rogers, Paul Pediatrics Medicine UBC Child & Family Research Institute progers@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=111<br />

Rolf,<br />

J.Douglas<br />

Romney, Marc Pathology &<br />

Laboratory<br />

Med<br />

Medicine Medicine UBC Interior Health Authority-Kelowna<br />

General Hospital<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Ronco, Juan Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Rosenberg,<br />

Frances<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

douglass.rolf@interiorhealth.ca<br />

mromney@providencehealth.bc.ca<br />

www.directory.ubc.ca/<br />

index.cfm<br />

http://www.pathology.<br />

ubc.ca/NewPathology/<br />

<strong>Clinical</strong>AssistantProfessor/<br />

Marc_Romney.html<br />

jronco@vanhosp.bc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=65892&_<br />

Type=Researchers-<br />

Database&_Title=Ronco-<br />

Dr.-Juan-J.<br />

Critical care, pulmonary<br />

Rosenbrg@providencehealth.bc.ca<br />

http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

Pulmonary COPD<br />

CNS Health<br />

Cancer<br />

Pulmonary Influenza<br />

ID/ infection Infection<br />

CV / cardiology<br />

ARDS


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

155<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Rowe,<br />

Timothy<br />

Rudnik,<br />

James<br />

Rupka,<br />

Dennis<br />

Russell,<br />

James<br />

Sadovnick, A.<br />

Dessa<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Medical<br />

Genetics<br />

Salhus, Terje Anesthesiology,<br />

Pharmacology<br />

&<br />

Therapeutics<br />

Salvarinova,<br />

Ramona<br />

Salvian,<br />

Anthony<br />

Sanatani,<br />

Shubhayan<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

trowe@unixg.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=41811&_<br />

Type=Researchers-Data-<br />

base&_Title=Rowe-Dr.-<br />

Timothy-C.<br />

Obstetrics / gynecology<br />

Menopause<br />

Fraser Health N/A N/A CNS, CV/ cardiology Addiction, acute<br />

coronary syndrome<br />

Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

jrussell@providencehealth.<br />

bc.ca<br />

http://www.icapture.<br />

ubc.ca/who/who_bios_<br />

james_russell.shtml<br />

sadovnik@infinet.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=699<br />

295927<br />

Medicine UBC B.C. Cancer Agency tsalhus@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

015308<br />

Pediatrics Medicine UBC Child & Family Research Institute rsalvari@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

015300<br />

Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

anthony.salvian@ubc.ca http://www.surgery.ubc.<br />

ca/faculty/asalvian.html<br />

Pediatrics Medicine UBC Child & Family Research Institute ssanatani@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=114<br />

ID/ infection, critical<br />

care<br />

Respiratory, sepsis<br />

CNS Brain/CNS<br />

Cancer Palliative care<br />

Metabolic/ endocrine Genetic disease<br />

Musculo-skeletal<br />

CV / cardiology Coronary disease


156<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

S<strong>and</strong>ers,<br />

Barry<br />

S<strong>and</strong>or,<br />

George<br />

Obstetrics &<br />

Gynecology<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Child & Family Research Institute obgroup@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=703<br />

446448<br />

Pediatrics Medicine UBC Child & Family Research Institute gs<strong>and</strong>or@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=115<br />

Obstetrics / gynecology<br />

CV / cardiology<br />

Gynecology<br />

Sauciuc, Delia B.C. Cancer Agency dsauciuc@bccancer.bc.ca N/A Cancer Brain/CNS, lung,<br />

prostate<br />

Savage, Kerry Medicine Medicine UBC B.C. Cancer Agency ksavage@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

007184<br />

Schechter,<br />

Martin<br />

Scheifele,<br />

David<br />

Schellenberg,<br />

Robert<br />

Health Care/<br />

Epidemiology,<br />

Population &<br />

Public Health<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Martin.schechter@ubc.ca http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

Pediatrics Medicine UBC Child & Family Research Institute dscheifele@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=117<br />

iCAPTURE Medicine UBC Providence Health Care Research<br />

Institute<br />

bschellenberg@mrl.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_bob_<br />

schellenberg.shtml<br />

Cancer Melanoma, lymphoma<br />

ID/ infection HIV<br />

ID/ infection DTP, influenza, MMR,<br />

pneumococcal<br />

Pulmonary Asthma<br />

Schimmele, C UVic Van Isl<strong>and</strong> Health Authority chrissch@uvic.ca N/A CNS Mental health<br />

Gastro-intestinal Liver disease<br />

Schreiber,<br />

Richard<br />

Pediatrics Medicine UBC Child & Family Research Institute rschreiber@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=118


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

157<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Schultz, Kirk Pediatrics Medicine UBC Child & Family Research Institute kschultz@interchange.<br />

ubc.ca<br />

Scudamore,<br />

Charles H.<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=119<br />

Surgery Medicine UBC UBC Campus charles.scudamore@vch.ca http://www.surgery.ubc.<br />

ca/faculty/cscudamore.<br />

html<br />

Sehn, Laurie Medicine Medicine UBC B.C. Cancer Agency lsehn@bccancer.bc.ca http://www.eventcare.<br />

ca/clients/cowc/bios/laurie_sehn.html<br />

Selby,<br />

Kathryn<br />

Pediatrics Medicine UBC Child & Family Research Institute kselby@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=382<br />

Shah, Amil Medicine Medicine UBC B.C. Cancer Agency ashah@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=724<br />

352776<br />

Shapiro, Jerry Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Shapiro, R.<br />

Jean<br />

Shariff,<br />

Salima<br />

Shenkier,<br />

Tamara<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

shapiro@interchange.ubc.ca http://www.skincarecentre.ca/about_us/doctors/<br />

jerry_shapiro.htm<br />

jean.shapiro@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=725<br />

275114<br />

Cancer, hematology,<br />

transplant<br />

Cancer Liver<br />

Leukemia, GVHD<br />

Cancer Lymphoma<br />

Musculo-skeletal Dystrophy<br />

Cancer Gastro-intestinal<br />

Dermatology Alopecia, psoriasis<br />

Transplant, cancer Melanoma<br />

Fraser Health N/A N/A CV / cardiology Cardiology<br />

Medicine Medicine UBC B.C. Cancer Agency tshenkier@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=728<br />

349574<br />

Cancer Breast


158<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Shepherd,<br />

John<br />

Shereck, Evan<br />

B.<br />

Simkus,<br />

Gerald<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

jshepher@bccancer.bc.ca http://www.leukemiabmtprogram.org/<br />

general_information/<br />

about_us/our_doctors/<br />

shepherd.html<br />

Pediatrics Medicine UBC Child & Family Research Institute eshereck@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=295<br />

Sin, Donald Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Cancer Leukemia<br />

Cancer/ hematology<br />

Fraser Health N/A N/A CV / cardiology Coronary disease<br />

dsin@mrl.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_don_<br />

sin.shtml<br />

Singh, Avash Pediatrics Medicine UBC Child & Family Research Institute ajsingh@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=384<br />

Pulmonary COPD<br />

Pulmonary RSV<br />

Singh, RA Van Isl<strong>and</strong> Health Authority N/A N/A Gastro-intestinal<br />

Singhal, Ash Surgery Medicine UBC Child & Family Research Institute ash.singhal@cw.bc.ca http://www.cfri.ca/ our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=384<br />

CNS Brain injury<br />

Metabolic/ endocrine Genetic disease<br />

Sirrs, S<strong>and</strong>ra Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Skarsgard,<br />

Eric<br />

s<strong>and</strong>ra.sirrs@vch.ca http://www.cyhrnet.ca/<br />

members/node/3576<br />

Surgery UBC Child & Family Research Institute eskarsgard@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=123<br />

Surgery Fetal diagnosis/<br />

therapy, neonatology


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

159<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Skippen,<br />

Peter<br />

Skoll,<br />

Am<strong>and</strong>a<br />

Skowronski,<br />

Danuta<br />

Smith,<br />

Clayton<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute pskippen@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=348<br />

Obstetrics &<br />

Gynecology<br />

Centre for Disease<br />

Control<br />

Medicine UBC Child & Family Research Institute askoll@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

search_results.asp<br />

Medicine UBC BC Centre for Disease Control danuta.skowronski@bccdc.<br />

ca<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Smith, Donna Orthopedics Medicine UBC Providence Health Care Research<br />

Institute<br />

http://www.cdc.ubc.ca/<br />

People/DanutaSkowronski.<br />

htm<br />

clsmith@bccancer.bc.ca http://www.terryfoxlab.<br />

ca/people/csmith/clayton.<br />

aspx<br />

dsmith@vbjc.ca www.orthosurgery.ubc.ca/<br />

faculty_bios/smith.html<br />

Smyth, John Pediatrics Medicine UBC Child & Family Research Institute jsmyth@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751146<br />

So, Alan Urologic <strong>Sciences</strong><br />

Solimano,<br />

Alfonso<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

alan.so@vch.ca http://www.prostatecentre.com/aboutus/aboutus.<br />

phppageID=148<br />

Pediatrics Medicine UBC Child & Family Research Institute asolimano@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751147<br />

Son, Wai Kon Fraser Health-Chilliwack General<br />

Hospital<br />

Song, Kevin Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Critical care, neonatology<br />

Obstetrics / gynecology<br />

Sepsis<br />

Pregnancy<br />

ID/ infection DTP, influenza<br />

Cancer Lymphoma<br />

Musculo-skeletal Orthopedics<br />

Neonatology Care<br />

Cancer, genitourinary Prostate<br />

Neonatology Care<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

ksong@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

004242<br />

Cancer Myeloma


160<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Sorokan, Todd Fraser Health N/A N/A Critical care Sepsis, pediatrics<br />

Cancer Breast<br />

Souliere,<br />

Sheila<br />

Medicine Medicine UBC B.C. Cancer Agency N/A https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012188<br />

Stark, Donald Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Steinbok,<br />

Paul<br />

Steiner,<br />

Theodore<br />

Steinhoff,<br />

Gary<br />

Stenstrom,<br />

Robert<br />

Stephenson,<br />

Mary<br />

Stevenson,<br />

Ron<br />

Stewart,<br />

Laura<br />

dstark@interchange.ubc.ca http://www.allergyfoundation.ca/website/<br />

donald_stark.html<br />

Surgery Medicine UBC Child & Family Research Institute psteinbok@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=127<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

B.C. Cancer Agency, Van Isl<strong>and</strong><br />

Health Authority<br />

Family Practice Medicine UBC Providence Health Care Research<br />

Institute<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Child & Family Research Institute mstephen@babies.bsd.<br />

uchicago.edu<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

tsteiner@interchange.ubc.ca http://www.ID.med.ubc.<br />

ca/Faculty/Faculty_Steiner.htm<br />

N/A www.bccancer.bc.ca/NR/<br />

exeres/014CD3CD-7811-<br />

4014-B067-A817EB955-<br />

FB2.htm<br />

robstenstrom@shaw.ca http://www.sphemerg.ca/<br />

research/stenstrom<br />

http://www.obstgyn.ca/About/dir_detail.<br />

htmID=80<br />

ronald.stevenson@ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751988<br />

Pediatrics Medicine UBC Child & Family Research Institute lstewart@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751150<br />

ID/ infection Infection<br />

CNS Brain injury<br />

Gastro-intestinal IBD<br />

Genitourinary, cancer Prostate, bladder<br />

Emergency medicine,<br />

pulmonary<br />

Obstetrics / gynecology<br />

Asthma<br />

Pregnancy<br />

Genitourinary Male urogenital<br />

Metabolic/ endocrine Genetic disease


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

161<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Stiver, Grant Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Stockler,<br />

Sylvia<br />

Stoessl, A<br />

Jonathan<br />

Stothers,<br />

Lynn<br />

Straatman,<br />

Lynn<br />

Strahlendorf,<br />

Caron<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

gstiver@interchange.ubc.ca http://www.ID.med.ubc.<br />

ca/Faculty/Dr__Grant_<br />

Stiver.htm<br />

Pediatrics Medicine UBC UBC Campus sstockler@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=255<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Urologic <strong>Sciences</strong><br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Pediatrics Medicine UBC Providence Health Care Research<br />

Institute<br />

jstoessl@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=39640&_<br />

Type=Researchers-<br />

Database&_Title=Stoessl-<br />

Dr.-A.-Jon<br />

lynns@interchange.ubc.ca http://urology.ubc.ca/wpcontent/uploads/2007/02/<br />

Stothers-L.pdf<br />

lstraatman@providencehealth.bc.ca<br />

http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=296<br />

Pediatrics Medicine UBC Child & Family Research Institute cstrahlendorf@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=261<br />

ID/ infection Infection<br />

Metabolic/ endocrine Genetic disease<br />

CNS Parkinson’s<br />

Genitourinary Bladder<br />

Transplant, CV/<br />

cardiology<br />

Stuart, David Fraser Health N/A N/A Cancer Breast<br />

Metabolic/ endocrine Diabetes<br />

Studney,<br />

Donald<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

N/A https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=772<br />

929244<br />

Cancer


162<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Sullivan,<br />

Kathleen<br />

Ophthalmology<br />

& Visual<br />

Science<br />

Sun, Sophie Medical Oncology<br />

Sutherl<strong>and</strong>,<br />

Heather<br />

Sutherl<strong>and</strong>,<br />

Judy<br />

Swenerton,<br />

Ken<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC UBC Campus kathleen_sullivan@telus.<br />

net<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751289<br />

Medicine UBC B.C. Cancer Agency ssun@bccancer.bc.ca N/A Cancer<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

hsutherl@bccancer.bc.ca http://www.bccrc.ca/tfl/<br />

people_hsutherl.html<br />

Ophthalmology Glaucoma<br />

Cancer Myeloma<br />

B.C. Cancer Agency jsutherl@bccancer.bc.ca N/A Cancer Lymphoma, myeloma.<br />

Leukemia<br />

Medicine Medicine UBC B.C. Cancer Agency kswener@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=778<br />

616995<br />

Swiston, John Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

swiston@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

014581<br />

Synnes, Anne Pediatrics Medicine UBC Child & Family Research Institute asynnes@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=129<br />

Takaro,<br />

Timothy<br />

Health <strong>Sciences</strong><br />

SFU ttakaro@sfu.ca www.fhs.sfu.ca/portal_memberdata/timt<br />

Tan Dy, C Van Isl<strong>and</strong> Health Authority N/A N/A Neonatology<br />

Cancer Urogenital<br />

Pulmonary Hypertension<br />

ID/ infection Fungal<br />

Pulmonary Allergies<br />

Tan, Peter Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

Tang, Bao Van Isl<strong>and</strong> Health Authority bao.tang@shaw.ca N/A Surgery Surgery<br />

Pulmonary Asthma, COPD<br />

Tan-Hogg,<br />

Wan<br />

Medicine Medicine<br />

– Respiratory<br />

Medicine<br />

UBC Providence Health Care Research<br />

Institute<br />

wtan@mrl.ubc.ca www.pacificlung.com/<br />

who_we_are.php


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

163<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Taylor,<br />

Marianne<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine Medicine UBC B.C. Cancer Agency mtaylor@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001204<br />

Taylor, Paul Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Teal, Philip Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Thiessen,<br />

Brian<br />

Thompson,<br />

David<br />

Thompson,<br />

Debbie<br />

Thornton,<br />

Allen E<br />

ptaylor@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage<br />

=personDetail&row=78<br />

7225483 http://www.<br />

providenceresearch.ca/<br />

directory/index.aspx<br />

teal@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=38022&_<br />

Type=Researchers-<br />

Database&_Title=Teal-<br />

Dr.-Philip-A.<br />

Medicine Medicine UBC B.C. Cancer Agency bthiessen@bccancer.bc.ca http://www.bccrc.ca/at/<br />

people_bthiessen.html<br />

Medicine Medicine UBC Child & Family Research Institute david.thompson@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=794<br />

911633<br />

Cancer Breast, colorectal<br />

Genitourinary Dialysis<br />

CNS Stroke<br />

Cancer CNS<br />

Obstetrics / gynecology<br />

Pregnancy<br />

Fraser Health N/A N/A CNS Depression<br />

Psychology SFU aethornt@sfu.ca http://www.sfu.ca/psyc/<br />

faculty/thorntona/<br />

Tinker, Anna Medicine Medicine UBC B.C. Cancer Agency atinker@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

014559<br />

Tomlin, D. Interior Health Authority-Kootenay<br />

Lake Hospital<br />

Townsend,<br />

Tiffany<br />

Neurology Medicine UBC Van Coastal Health Research<br />

Institute<br />

CNS Schizophrenia,<br />

cognitive<br />

Cancer Urogenital<br />

N/A N/A Metabolic/ endocrine Diabetes<br />

tiffany.townsend@vch.ca http://vch.eduhealth.ca/<br />

PDFs/FM/FM.470.V279.pdf<br />

CNS Epilepsy


164<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Townson,<br />

Andrea<br />

Rehabilitation<br />

<strong>Sciences</strong><br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Toze, Cynthia Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Traboulsee,<br />

Anthony<br />

Truong,<br />

Pauline<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

atownson@vanhosp.bc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=65156&_<br />

Type=Researchers-Data-<br />

base&_Title=Townson-<br />

Dr.-Andrea-F.<br />

ctoze@bccancer.bc.ca http://www.leukemiabmtprogram.org/general_<br />

information/about_us/<br />

our_doctors/toze.html<br />

trabouls@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=62908&_<br />

Type=Researchers-Data-<br />

base&_Title=Traboulsee-<br />

Dr.-Anthony<br />

Surgery Medicine UBC B.C. Cancer Agency ptruong@bccancer.bc.ca http://www.surgery.ubc.<br />

ca/faculty/ptruong.html<br />

Tsang, Peter Medicine Medicine UBC Child & Family Research Institute ptsang@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001205<br />

Tsui, Joseph Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Tsui, Winston General Internal<br />

Medicine<br />

jtsui@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

005466<br />

CNS SCI<br />

Cancer, hematology Lymphoma<br />

CNS MS<br />

Fraser Health N/A N/A CV / cardiology<br />

Tucker, Lori Pediatrics Medicine UBC Child & Family Research Institute ltucker@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=134<br />

Cancer Breast, prostate<br />

Hematology Thrombosis/ coagulation<br />

CNS Parkinson’s<br />

Autoimmune,<br />

genitourinary<br />

Rheumatology, renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

165<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Tung, Stanley Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Tyndall, Mark Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Umedaly,<br />

Hamed<br />

Anesthesia Medicine UBC Van Coastal Health Research<br />

Institute<br />

Ur, Ehud Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

van Eeden,<br />

Stephan F.<br />

Vickars, Linda<br />

M.<br />

Respiratory<br />

Medicine<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

stung@providencehealth.<br />

bc.ca<br />

http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

mtyndall@cfenet.ubc.ca http://www.cmeonhiv.<br />

com/pub/dr..mark.tyndall.<br />

php<br />

hamed.umedaly@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=817<br />

585775<br />

ehud.ur@vch.ca www.obesitynetwork.<br />

ca/members/view.<br />

aspxID=336&title=Ehud+Ur<br />

svaneeden@mrl.ubc.ca www.pacificlung.com/<br />

who_we_are.php<br />

lvickars@providencehematology.com<br />

http://www.cbr.ubc.ca/<br />

research_lvickars.htm<br />

Virani, Sean Medicine Medicine UBC UBC Campus N/A https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

014082<br />

Von<br />

Dadelszen,<br />

Peter<br />

Vorobeychik,<br />

Galina<br />

Vrabec,<br />

George<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Child & Family Research Institute pdadelszen@cw.bc.ca; pvd@<br />

cw.bc.ca<br />

Medicine Medicine UBC Fraser Health galina.vorobeychik@<br />

fraserhealth.ca<br />

http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=140<br />

CV / cardiology Coronary disease<br />

ID/ infection HIV<br />

CV / cardiology Coronary bypass<br />

Metabolic/ endocrine Neuroendocrine<br />

disorders, diabetes,<br />

dyslipidemia,<br />

obesity<br />

Pulmonary Chronic bronchitis,<br />

emphysema<br />

Hematology Thrombosis/ coagulation,<br />

myelodysplastic<br />

syndromes<br />

CV / cardiology Coronary disease<br />

Obstetrics / gynecology,<br />

neonatology<br />

N/A CNS MS<br />

Fraser Health N/A N/A Cancer Prostate<br />

Wai, Elaine Medicine Medicine UBC B.C. Cancer Agency N/A http://www.surgery.ubc.<br />

ca/faculty/ewai.html<br />

Pregnancy, neonatology<br />

Cancer Breast, lung


166<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Wambera,<br />

Kati<br />

Warburton,<br />

Rebecca N<br />

Warriner,<br />

Brian<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute N/A N/A CNS Brain/CNS<br />

Public Administration<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Wasan, Kishor Pharmaceutical<br />

<strong>Sciences</strong><br />

Watson, Peter<br />

H<br />

Microbiology/<br />

Biochemistry<br />

UVic rnwarbur@uvic.ca http://publicadmin.uvic.<br />

ca/aboutUs/staffPersonal/<br />

warburton.php<br />

Medicine UBC Providence Health Care Research<br />

Institute/ Van Coastal Health<br />

Research Institute<br />

brian.warriner@vch.ca<br />

bwarrin@interchange.<br />

ubc.ca<br />

http://www.pharmacology.ubc.ca/FS%20sub%20<br />

dir/FS%20Warriner.html<br />

UBC UBC Campus kwasan@interchange.ubc.ca http://www.pharmacy.<br />

ubc.ca/faculty_staff/faculty/pharm_bio/pharm_<br />

bio_kishor_wasan.html<br />

UVic B.C. Cancer Agency Deeley<br />

Research Centre<br />

Webb, John Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Weinerman,<br />

Brian<br />

pwatson@bccancer.bc.ca http://www.bccrc.ca/drc/<br />

people_pwatson1.html<br />

webb@providencehealth.<br />

bc.ca<br />

http://www.bccrc.ca/drc/<br />

people_jwebb.html<br />

Medicine Medicine UBC B.C. Cancer Agency bweinerm@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=850<br />

251913<br />

Other<br />

Anesthesiology, CV/<br />

cardiology<br />

Cancer Breast<br />

Cancer<br />

Palliative care, cardiac<br />

surgery, pain<br />

CV / cardiology Coronary bypass,<br />

myocardial infarction,<br />

cardiac surgery,<br />

angioplasty/ stent<br />

Cancer Pancreas<br />

Weinerman, R Van Isl<strong>and</strong> Health Authority N/A N/A CNS Psychiatry<br />

Liver<br />

Weiss, Alan Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Weiss,<br />

Margaret<br />

alan.weiss@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=851<br />

020528<br />

Psychiatry Medicine UBC Child & Family Research Institute margaret.weiss@me.com http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=145<br />

Gastro-intestinal,<br />

cancer<br />

CNS Mental health


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

167<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Wensley,<br />

David<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute dwensley@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=853<br />

018927<br />

White, Colin Pediatrics Medicine UBC Child & Family Research Institute cwhite@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=247<br />

Wijeyesinghe,<br />

ECR<br />

Wilcox,<br />

Pearce G.<br />

Kidney Clinic Interior Health Authority-Royal<br />

Inl<strong>and</strong> Hospital<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Pulmonary, critical<br />

care<br />

ARDS<br />

Genitourinary Renal<br />

N/A N/A Genitourinary Renal<br />

pwilcox@providencehealth.<br />

bc.ca<br />

http://www.icapture.<br />

ubc.ca/who/who_bios_<br />

pearce_wilcox.shtml<br />

Pulmonary Cystic fibrosis,<br />

asthma, COPD<br />

Williams, R Van Isl<strong>and</strong> Health Authority N/A N/A CNS Psychiatry<br />

Wilson,<br />

Kenneth<br />

Winkler,<br />

Lawrence<br />

Wong,<br />

Christopher<br />

Wong,<br />

Graham<br />

Medicine Medicine UBC B.C. Cancer Agency kwilson@bccancer.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=869<br />

006119<br />

General Internal<br />

Medicine<br />

Medicine UBC Van Isl<strong>and</strong> Health Authority-<br />

Nanaimo<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

drwink@shaw.ca www.drlwinkler.com CV/ cardiology, critical<br />

care<br />

Cancer Gastro-intestinal,<br />

melanoma<br />

Fraser Health N/A N/A ID/ infection Diarrhea<br />

gcwong@interchange.<br />

ubc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

006503<br />

Wong, Peter Pediatrics Medicine UBC Child & Family Research Institute pwong@interchange.ubc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=383<br />

CV / cardiology Acute coronary<br />

syndrome<br />

CNS Epilepsy/ seizures<br />

Wood, G Van Isl<strong>and</strong> Health Authority N/A N/A Critical care Intensive care


168<br />

BRITISH COLUMBIA<br />

6.1 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed in Alphabetical Order (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Woolfenden,<br />

Andrew<br />

Worsley,<br />

Daniel<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Radiology Medicine UBC Van Coastal Health Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Awoolf6175@aol.com https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

001215<br />

dan.worsley@vch.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=882<br />

380020<br />

Wu, John K. Pediatrics Medicine UBC Child & Family Research Institute jwu@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=249<br />

Wyatt,<br />

Christopher<br />

Oral Health <strong>Sciences</strong><br />

Dentistry UBC UBC Campus cwyatt@interchange.ubc.ca http://www.prosthodontist.ca/about.html<br />

Yang, Tung Medicine Medicine UBC UBC Campus tc_yang@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

012839<br />

Yatham,<br />

Lakshmi<br />

Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

Ye, Jian Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

yatham@interchange.ubc.ca http://www.crestbd.<br />

ca/researchers/yathamlakshmi.php<br />

jye@providencehealth.bc.ca http://www.surgery.ubc.<br />

ca/faculty/jye.html<br />

Yee, Adrian Medicine Medicine UBC B.C. Cancer Agency ayee@bccancer.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

010540<br />

Yeung, Choi<br />

Kit<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

cyeung@vanhosp.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=890<br />

066170<br />

CNS Stroke<br />

CNS Stroke<br />

Hematology Genetic disease, infection,<br />

thrombosis/<br />

coagulation<br />

Dental Hygiene<br />

Metabolic/ endocrine Diabetes<br />

CNS Bipolar<br />

CV / cardiology Cardiac surgery<br />

Cancer Lymphoma<br />

Genitourinary Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

169<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Yeung-Lai-<br />

Wah, John<br />

Cardiology Medicine UBC Providence Health Care Research<br />

Institute<br />

Yoshida, Eric Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Young, Allan Psychiatry Medicine UBC Van Coastal Health Research<br />

Institute<br />

Younger,<br />

Alastair<br />

Orthopedics Medicine UBC Providence Health Care Research<br />

Institute<br />

INSTITUTION EMAIL WEBSITE DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

jayeung@axion.net http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

eric.yoshida@vch.ca http://www.cedarproject.<br />

ca/pages/A5_11yoshida.<br />

html; https://www.directory.ubc.ca/index.cfmpag<br />

e=personDetail&row=89<br />

9751745<br />

allan.young@ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

010214<br />

asyounger@shaw.ca http://www.specialistclinic.ca/physicians_AlastairYounger.php<br />

CV / cardiology Coronary disease<br />

Gastro-intestinal, ID/<br />

infection<br />

Yuen, Anna Fraser Health N/A N/A ID/ infection<br />

Zhou, Youwen Dermatology &<br />

Skin Science<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

ywzhou@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=59990&_<br />

Type=Researchers-<br />

Database&_Title=Zhou-<br />

Dr.-Youwen<br />

Hepatitis<br />

CNS Bipolar<br />

Musculo-skeletal Orthopedics<br />

Metabolic/ endocrine,<br />

dermatology<br />

Endocrinology


170<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty<br />

Note that a number of investigators are listed multiple times due to their clinical trials activities in more than one area.<br />

DISEASE<br />

SPECIALTY<br />

ANESTHESIOLOGY Ansermino,<br />

Mark<br />

ANESTHESIOLOGY Bowering,<br />

John<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

ANESTHESIOLOGY Choi, Peter Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UBC Child & Family<br />

Research Institute<br />

Anesthesia Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

ANESTHESIOLOGY Cole, Colm Anesthesia Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

ANESTHESIOLOGY Lauder, Gillian Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

ANESTHESIOLOGY Merchant,<br />

Richard<br />

ANESTHESIOLOGY Puil, Ernie Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

ANESTHESIOLOGY Warriner,<br />

Brian<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

UBC Child & Family<br />

Research Institute<br />

Fraser Health - Royal<br />

Columbian Hospital<br />

mansermino@cw.bc.ca www.cfri.ca/our_research/researchers/search_researchers/researcher_detail.aspID=3<br />

jkbow@shaw.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=768<br />

71500<br />

PeterT.Choi@vch.ca http://www.apt.ubc.ca/anesthesiology/Vancouver_General_Hospital/Department_Members/Dr_Peter_Choi.<br />

htm<br />

cole@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1469<br />

69188<br />

glauder@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=284<br />

N/A N/A<br />

Medicine UBC UBC Campus puil@neuro.pharmacology.<br />

ubc.ca<br />

Medicine UBC Providence Health<br />

Care Research Institute/<br />

Van Coastal<br />

Health Research<br />

Institute<br />

brian.warriner@vch.ca; bwarrin@interchange.ubc.ca<br />

N/A<br />

http://www.pharmacology.ubc.ca/<br />

FS%20sub%20dir/FS%20Warriner.<br />

html<br />

Pediatrics<br />

Hypertension<br />

Pain<br />

Pediatrics<br />

Palliative care, cardiac<br />

surgery, pain


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

171<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

AUTOIMMUNE Cabral, David Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

AUTOIMMUNE Dunne, James<br />

V.<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

AUTOIMMUNE Gross, K. Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

AUTOIMMUNE Houghton,<br />

Kristin<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

AUTOIMMUNE Kelsall, John T Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

AUTOIMMUNE Marra, Carlo Pharmaceutical<br />

<strong>Sciences</strong><br />

AUTOIMMUNE Offer, Robert Rheumatology<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

AUTOIMMUNE Petty, Ross Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

AUTOIMMUNE Tucker, Lori Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CANCER Agranovich,<br />

Alex<strong>and</strong>er<br />

CANCER Al-Tourah,<br />

Abdul<br />

Radiation<br />

Oncology &<br />

Developmental<br />

Radiotherapeutics<br />

dcabral@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=289<br />

drjdunne@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2047<br />

69036<br />

Rheumatology,<br />

osteoporosis<br />

N/A N/A Arthritis<br />

khoughton@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=286<br />

jkelsall@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

52758<br />

Carlo.marra@ubc.ca www.pharmacy.ubc.ca/faculty_staff/<br />

faculty/practice/practice_carlo_marra.<br />

html<br />

Hypertension, GVHD<br />

Arthritis<br />

Arthritis<br />

roffer@shaw.ca www.directory.ubc.ca/index.cfm Arthritis<br />

rpetty@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=6270<br />

46117<br />

ltucker@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=134<br />

UBC B.C. Cancer Agency N/A http://www.surgery.ubc.ca/faculty/<br />

aagranovich.html<br />

Arthritis, psoriasis<br />

Rheumatology<br />

Rheumatology,<br />

renal<br />

Prostate<br />

B.C. Cancer Agency aaltoura@bccancer.bc.ca N/A Breast, lymphoma


172<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

CANCER Amil, S B.C. Cancer Agency N/A N/A Gastro-intestinal<br />

CANCER Anderson, H. B.C. Cancer Agency N/A N/A Gastro-intestinal,<br />

lung<br />

CANCER Atkins, M<br />

Stella<br />

CANCER Attwell,<br />

Andrew<br />

CANCER Balneaves,<br />

Lynda<br />

CANCER Barnett,<br />

Jeffrey Ben<br />

CANCER Barnett,<br />

Michael<br />

CANCER Beckham,<br />

Wayne Allan<br />

School of<br />

Computing<br />

Science<br />

Nursing Applied Science<br />

Health<br />

Information<br />

Science<br />

SFU stella@cs.sfu.ca http://www.cs.sfu.ca/~stella/ Melanoma, radiotherapy/<br />

imaging<br />

B.C. Cancer Agency N/A N/A Breast, prostate<br />

UBC Van Coastal Health<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Physics &<br />

Astronomy<br />

CANCER Behrens, C Van Isl<strong>and</strong> Health<br />

Authority<br />

CANCER Bernstein,<br />

Vanessa<br />

CANCER Berrang,<br />

Tanya<br />

CANCER Black, Peter Urologic <strong>Sciences</strong><br />

CANCER Brotto, Lori Obstetrics &<br />

Gynecology<br />

lynda.balneaves@nursing.ubc.ca http://www.nursing.ubc.ca/faculty/<br />

biopage.aspxc=65.5133574166368<br />

UVic B.C. Cancer Agency jebarnet@uvic.ca N/A<br />

mbarnett@bccancer.bc.ca http://www.leukemiabmtprogram.<br />

org/general_information/about_us/<br />

our_doctors/barnett.html<br />

UVic B.C. Cancer Agency wbeckham@bccancer.bc.ca http://www.phys.uvic.ca/medphys/<br />

people/WB/beckham.html<br />

N/A N/A<br />

Medicine UBC B.C. Cancer Agency vbernste@bccancer.bc.ca N/A Breast<br />

Surgery Radiation<br />

Oncology &<br />

Developmental<br />

Radiotherapeutics<br />

UBC B.C. Cancer Agency N/A http://www.surgery.ubc.ca/faculty/<br />

berrang.html<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Women's Health<br />

Research Institute<br />

N/A www.prostatecentre.com/aboutus/<br />

aboutus.phppageID=187<br />

lori.brotto@vch.ca www.whri.org/projects<strong>and</strong>people/<br />

people/Brotto.htm<br />

Prostate<br />

Leukemia<br />

Radiotherapy<br />

Breast<br />

Bladder cancer<br />

Cervical, endometrial,<br />

gynecology


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

173<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CANCER Brown, Carl Surgery Medicine UBC Providence Health<br />

Care Research Institute/<br />

B.C. Cancer<br />

Agency<br />

CANCER Chambers,<br />

Keith<br />

CANCER Cheung,<br />

Winson<br />

Health Care/<br />

Epidemiology<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

cbrown@providencehealth.bc.ca http://www.providencehealthcare.org/<br />

colorectalsurgery/Carl-Brown.html<br />

kchamber@vanhosp.bc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=54732&_<br />

Type=Researchers-Database&_<br />

Title=Chambers-Dr.-G.-Keith<br />

B.C. Cancer Agency N/A N/A<br />

CANCER Chi, Kim Oncology Medicine UBC B.C. Cancer Agency kchi@bccancer.bc.ca http://www.prostatecentre.com/aboutus/aboutus.phppageID=166<br />

CANCER Chia, Stephen Oncology Medicine UBC B.C. Cancer Agency schia@bccancer.bc.ca https://www.directory.ubc.ca/index.cf<br />

mpage=personDetail&row=1000001<br />

161 http://www.eventcare.ca/clients/<br />

cowc/bios/stephen_chia.html<br />

CANCER Chow, Victor<br />

DW<br />

Urologic <strong>Sciences</strong><br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

N/A http://www.ubcfertility.com/drchow.<br />

php<br />

CANCER Connors, Joe Medicine Medicine UBC B.C. Cancer Agency JConnors@bccancer.bc.ca www.bccancer.bc.ca/RES/ResearchPrograms/LymphoidCancers/researchers.<br />

htm#connors<br />

CANCER Crabb, Simon B.C. Cancer Agency N/A N/A Breast<br />

CANCER Czerkawski,<br />

Barbara<br />

B.C. Cancer Agency bczerkaw@bccancer.bc.ca N/A Breast<br />

GVHD<br />

CANCER Davis, Jeffrey Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CANCER Davison, Joyce Nursing UBC Van Coastal Health<br />

Research Institute<br />

CANCER Dickson, G.<br />

Brentley<br />

Family<br />

Practice<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Dix, David Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

jdavis@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=269<br />

joyce.davison@vch.ca www.prostatecentre.com/aboutus/<br />

aboutus.phppageID=158<br />

N/A N/A<br />

ddix@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=260<br />

Colorectal, pain<br />

Prostate<br />

Prostate<br />

Breast, head/neck<br />

Urogenital<br />

Lymphoma<br />

Prostate cancer<br />

Complications


174<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CANCER Ellard, Susan Medical<br />

Oncology<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UBC B.C. Cancer Agency sellard@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

52752<br />

CANCER Fenton, Dave Radiology UBC B.C. Cancer Agency davfent@yahoo.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

016418<br />

CANCER Fisher, Charles Orthopedics Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Fitzgerald,<br />

Catherine<br />

CANCER Forrest,<br />

Donna<br />

CANCER Fryer,<br />

Christopher<br />

CANCER Fyles, Gillian Family<br />

Practice<br />

CANCER Gelmon,<br />

Karen<br />

CANCER Gleave,<br />

Martin<br />

CANCER Goldenberg,<br />

Larry<br />

vanspine@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=45360&_<br />

Type=Researchers-Database&_<br />

Title=Fisher-Dr.-Charles-G.<br />

Oncology Medicine UBC B.C. Cancer Agency cfitzger@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

003512<br />

Medicine Medicine UBC B.C. Cancer Agency dforrest@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

003478<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

cfryer@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=262<br />

UBC B.C. Cancer Agency gfyles@bccancer.bc.ca http://www.coag.uvic.ca/eolcare/gillian_fyles.htm<br />

Oncology Medicine UBC B.C. Cancer Agency kgelmon@bccancer.bc.ca http://www.bccrc.ca/at/people_<br />

kgelmon.html<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

gleave@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=63578&_<br />

Type=Researchers-Database&_<br />

Title=Gleave-Dr.-Martin-E.<br />

research@vanhosp.bc.ca http://www.prostatecentre.com/aboutus/aboutus.phppageID=118<br />

Breast, renal,<br />

prostate, MDR,<br />

urogenital<br />

Lung<br />

SCI, brain<br />

Gastro-intestinal<br />

Leukemia<br />

Brain/CNS<br />

Palliative care<br />

Breast<br />

Prostate<br />

Prostate


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

175<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CANCER Guns, Emma S. Urologic <strong>Sciences</strong><br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

emma.guns@vch.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=80657&_<br />

Type=Researchers-Database&_<br />

Title=Guns-Dr.-Emma-S.<br />

CANCER Gurjal, A B.C. Cancer Agency N/A http://surrey-bc.cofars.ca/dr-gurjalanagha/93367/<br />

CANCER Halperin, Ross B.C. Cancer Agency rhalperin@bcancer.bc.ca N/A Prostate<br />

Palliative care<br />

CANCER Hawley,<br />

Philippa<br />

General Internal<br />

Medicine<br />

CANCER Heywood, M Obstetrics &<br />

Gynecology<br />

Medicine UBC B.C. Cancer Agency phawley@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001174<br />

Medicine UBC B.C. Cancer Agency mheywood@bccancer.bc.ca http://www.bccancer.bc.ca/<br />

HPI/SON/Council/members/<br />

Dr.+Mark+Heywood.htm<br />

CANCER Ho, Cheryl Medicine Medicine UBC B.C. Cancer Agency cho@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

014081<br />

CANCER Hogge, Donna Medicine Medicine UBC Van Coastal Health<br />

Research Institute/<br />

B.C. Cancer Agency<br />

dhogge@bccancer.bc.ca http://www.bccrc.ca/tfl/people_dhogge.html<br />

CANCER Hoskins, Paul Medicine Medicine UBC B.C. Cancer Agency phoskins@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=3452<br />

71858<br />

CANCER Hukin,<br />

Juliette<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

jhukin@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=58<br />

CANCER Jasas, K B.C. Cancer Agency N/A N/A Lung<br />

CANCER Kennecke,<br />

Hagan<br />

Medicine Medicine UBC B.C. Cancer Agency hkennecke@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012828<br />

CANCER Khoo, Kong Medicine Medicine UBC B.C. Cancer Agency kkhoo@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=3981<br />

52570<br />

Prostate<br />

Colorectal<br />

Urogenital<br />

Lung<br />

Leukemia<br />

Urogenital, lymphoma<br />

Brain/CNS<br />

Gastro-intestinal,<br />

breast<br />

Brain/CNS


176<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

CANCER Kim, David B.C. Cancer Agency dkim@bccancer.bc.ca http://kelowna-bc.cofars.ca/dr-kimdavid/100214/<br />

CANCER Kinahan,T. Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

Prostate<br />

N/A N/A Bladder<br />

CANCER Klasa, Richard Medicine Medicine UBC B.C. Cancer Agency rklasa@bccancer.bc.ca http://www.bccrc.ca/at/people_rklasa.<br />

html<br />

CANCER Klimo, Paul Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Knowling,<br />

Meg<br />

CANCER Kollmannsberger,<br />

Christian<br />

pklimo@direct.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=4089<br />

13180<br />

Medicine Medicine UBC B.C. Cancer Agency mknowling@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=4116<br />

80194<br />

UBC Feb<br />

2009,<br />

Medicine,<br />

but not<br />

found on<br />

database<br />

now<br />

B.C. Cancer Agency ckollmannsberger@bccancer.<br />

bc.ca<br />

http://www.bccrc.ca/at/people_ckollmannsberger.html<br />

CANCER Kwan, Winkle Medicine Medicine UBC B.C. Cancer Agency N/A http://www.surgery.ubc.ca/faculty/<br />

wkwan.html<br />

CANCER Kwon, Janice Obstetrics &<br />

Gynecology<br />

CANCER Lam, Wendy Oncology/<br />

Hematology<br />

CANCER Laskin,<br />

Janessa<br />

Medicine UBC B.C. Cancer Agency<br />

/ Van Coastal Health<br />

Research Institute<br />

Fraser Health<br />

Authority-Burnaby<br />

Hospital<br />

N/A www.powerstudy.ca/profile/janicekwon<br />

Lymphoma<br />

Breast, colorectal<br />

Gastro-intestinal<br />

Colorectal, kidney,<br />

gastro-intestinal,<br />

urogenital, liver<br />

Prostate<br />

Cervical, endometrial,<br />

gynecology<br />

wylam@telus.net N/A Multiple myeloma,<br />

metastatic, breast,<br />

lung, idiopathic<br />

thrombocytic<br />

purpura<br />

Medicine Medicine UBC B.C. Cancer Agency jlaskin@bccancer.bc.ca http://www.bccrc.ca/at/people_<br />

jlaskin.html<br />

Lung


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

177<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

CANCER Le, Lyly Medicine Medicine UBC B.C. Cancer Agency lle@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

010825<br />

CANCER Lee,<br />

Christopher<br />

Medicine Medicine UBC B.C. Cancer Agency clee@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

53751<br />

CANCER Lee, Ursula Medicine Medicine UBC B.C. Cancer Agency ulee@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51018<br />

CANCER Leger, Chantal<br />

S.<br />

CANCER Leitch,<br />

Heather<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

cleger@providencehematology.<br />

com<br />

hleitch@providencehematology.<br />

com<br />

CANCER Lim, Howard B.C. Cancer Agency N/A N/A<br />

CANCER Lohrisch,<br />

Caroline<br />

CANCER MacLean,<br />

Grant<br />

CANCER Macpherson,<br />

Nichol<br />

CANCER Maguire, John Pathology &<br />

Laboratory<br />

Med<br />

CANCER Martin, Lee<br />

Ann<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012133<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012134<br />

Medicine Medicine UBC B.C. Cancer Agency N/A https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012184<br />

Medicine Medicine UBC B.C. Cancer Agency gmaclean@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

006599<br />

Medicine Medicine UBC B.C. Cancer Agency nmacpher@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001184<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

john.maguire@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51645<br />

Medicine Medicine UBC B.C. Cancer Agency lmartin@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001188<br />

Colorectal, pancreas,<br />

prostate<br />

Lung, MDR, melanoma<br />

Urogenital<br />

Leukemia, lymphoma<br />

Leukemia, myeloma<br />

Breast, gastrointestinal<br />

Gastro-intestinal<br />

Breast, lymphoma<br />

Brain/CNS<br />

Breast


178<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

CANCER Martins, Heidi Medicine Medicine UBC B.C. Cancer Agency hmartins@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

002805<br />

CANCER McKenzie,<br />

Donald<br />

Family<br />

Practice<br />

Medicine UBC UBC Campus kari@interchange.ubc.ca http://www.hkin.educ.ubc.ca/faculty/<br />

mckenzied/mckenzied.htm<br />

CANCER Melosky, Barb Medicine Medicine UBC B.C. Cancer Agency bmelosky@bccancer.bc.ca http://www.eventcare.ca/clients/<br />

cowc/bios/barbara_melosky.html<br />

CANCER Michels, Jorg B.C. Cancer Agency jmichels@bccancer.bc.ca http://www.bccrc.ca/drc/people_jmichels.html<br />

CANCER Miller, Dianne Obstetrics &<br />

Gynecology<br />

CANCER Mirch<strong>and</strong>ani,<br />

D.<br />

CANCER Mohamed,<br />

Islam<br />

Medicine UBC BCCA/ Van Coastal<br />

Health Research<br />

Institute<br />

Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

B.C. Cancer Agency/<br />

Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

dmiller@bccancer.bc.ca www.obstgyn.ca/About/DivisionGyne-<br />

Onc.html<br />

Urogenital, kidney,<br />

lung<br />

Breast<br />

Gastro-intestinal,<br />

lung<br />

Urogenital<br />

N/A N/A Breast<br />

imohamed@bccancer.bc.ca N/A Lung<br />

CANCER Murray, Nevin Medicine Medicine UBC B.C. Cancer Agency nmurray@bccancer.bc.ca http://www.bccrc.ca/at/people_nmurray.html<br />

CANCER Nelems, B. Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

CANCER Nevill, Thomas Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Noble,<br />

Michael<br />

Cervical, endometrial,<br />

gynecology<br />

Lung<br />

N/A N/A Lung<br />

tnevill@bccancer.bc.ca http://www.canadianhematologysociety.org/exec_tomnevill.htm<br />

Fraser Health N/A N/A Various<br />

CANCER Norris, B B.C. Cancer Agency N/A N/A Breast<br />

CANCER O'Reilly, Susan Medicine UBC B.C. Cancer Agency SOReilly@bccancer.bc.ca www.bccrc.ca/at/people_soreilly.html<br />

Leukemia, thrombocytopenia


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

179<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CANCER Pai, Howard Health<br />

Information<br />

Science<br />

CANCER Pansegrau,<br />

Gary<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UVic B.C. Cancer Agency hpai@uvic.ca hpai@bccancer.<br />

bc.ca<br />

http://hinf.uvic.ca/people/Pai.php Brain/CNS<br />

Medicine Medicine UBC B.C. Cancer Agency gpansegrau@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

010826<br />

CANCER Petrik, David B.C. Cancer Agency dpetrik@bccancer.bc.ca N/A Prostate<br />

CANCER Pickles, Tom Surgery Medicine UBC B.C. Cancer Agency N/A www.surgery.ubc.ca/faculty/tpickles.<br />

html<br />

CANCER Rao, Sanjay Medicine Medicine UBC B.C. Cancer Agency srao@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012835<br />

CANCER Reed, Melanie B.C. Cancer Agency mreed@bccancer.bc.ca N/A Breast<br />

CANCER Rogers, Paul Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CANCER Salhus, Terje Anesthesiology,<br />

Pharmacology<br />

&<br />

Therapeutics<br />

progers@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=111<br />

Medicine UBC B.C. Cancer Agency tsalhus@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

015308<br />

Breast<br />

Urological, radiotherapy<br />

Colorectal, lung,<br />

head/neck, melanoma,<br />

pancreas,<br />

prostate<br />

Palliative care<br />

CANCER Sauciuc, Delia B.C. Cancer Agency dsauciuc@bccancer.bc.ca N/A Brain/CNS, lung,<br />

prostate<br />

CANCER Savage, Kerry Medicine Medicine UBC B.C. Cancer Agency ksavage@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

007184<br />

CANCER Schultz, Kirk Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CANCER Scudamore,<br />

Charles H.<br />

kschultz@interchange.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=119<br />

Surgery Medicine UBC UBC Campus charles.scudamore@vch.ca http://www.surgery.ubc.ca/faculty/<br />

cscudamore.html<br />

CANCER Sehn, Laurie Medicine Medicine UBC B.C. Cancer Agency lsehn@bccancer.bc.ca http://www.eventcare.ca/clients/<br />

cowc/bios/laurie_sehn.html<br />

Melanoma, lymphoma<br />

Leukemia, GVHD<br />

Liver<br />

Lymphoma


180<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

CANCER Shah, Amil Medicine Medicine UBC B.C. Cancer Agency ashah@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7243<br />

52776<br />

CANCER Shapiro, R.<br />

Jean<br />

CANCER Shenkier,<br />

Tamara<br />

CANCER Shepherd,<br />

John<br />

CANCER Shereck, Evan<br />

B.<br />

CANCER Smith,<br />

Clayton<br />

CANCER So, Alan Urologic <strong>Sciences</strong><br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

jean.shapiro@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7252<br />

75114<br />

Medicine Medicine UBC B.C. Cancer Agency tshenkier@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7283<br />

49574<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Song, Kevin Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Souliere,<br />

Sheila<br />

CANCER Steinhoff,<br />

Gary<br />

CANCER Strahlendorf,<br />

Caron<br />

jshepher@bccancer.bc.ca http://www.leukemiabmtprogram.<br />

org/general_information/about_us/<br />

our_doctors/shepherd.html<br />

eshereck@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=295<br />

clsmith@bccancer.bc.ca http://www.terryfoxlab.ca/people/<br />

csmith/clayton.aspx<br />

alan.so@vch.ca http://www.prostatecentre.com/aboutus/aboutus.phppageID=148<br />

ksong@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

004242<br />

Medicine Medicine UBC B.C. Cancer Agency N/A https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012188<br />

B.C. Cancer Agency,<br />

Van Isl<strong>and</strong> Health<br />

Authority<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

N/A www.bccancer.bc.ca/NR/<br />

exeres/014CD3CD-7811-4014-B067-<br />

A817EB955FB2.htm<br />

cstrahlendorf@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=261<br />

CANCER Stuart, David Fraser Health N/A N/A Breast<br />

Gastro-intestinal<br />

Melanoma<br />

Breast<br />

Leukemia<br />

Lymphoma<br />

Prostate<br />

Myeloma<br />

Breast<br />

Prostate, bladder


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

181<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CANCER Sun, Sophie Medical<br />

Oncology<br />

CANCER Sutherl<strong>and</strong>,<br />

Heather<br />

CANCER Sutherl<strong>and</strong>,<br />

Judy<br />

CANCER Swenerton,<br />

Ken<br />

CANCER Taylor,<br />

Marianne<br />

CANCER Thiessen,<br />

Brian<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC B.C. Cancer Agency ssun@bccancer.bc.ca N/A<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

hsutherl@bccancer.bc.ca http://www.bccrc.ca/tfl/people_<br />

hsutherl.html<br />

Myeloma<br />

B.C. Cancer Agency jsutherl@bccancer.bc.ca N/A Lymphoma, myeloma.<br />

Leukemia<br />

Medicine Medicine UBC B.C. Cancer Agency kswener@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7786<br />

16995<br />

Medicine Medicine UBC B.C. Cancer Agency mtaylor@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001204<br />

Medicine Medicine UBC B.C. Cancer Agency bthiessen@bccancer.bc.ca http://www.bccrc.ca/at/people_<br />

bthiessen.html<br />

CANCER Tinker, Anna Medicine Medicine UBC B.C. Cancer Agency atinker@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

014559<br />

CANCER Toze, Cynthia Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Truong,<br />

Pauline<br />

CANCER Vrabec,<br />

George<br />

ctoze@bccancer.bc.ca http://www.leukemiabmtprogram.<br />

org/general_information/about_us/<br />

our_doctors/toze.html<br />

Surgery Medicine UBC B.C. Cancer Agency ptruong@bccancer.bc.ca http://www.surgery.ubc.ca/faculty/<br />

ptruong.html<br />

Urogenital<br />

Breast, colorectal<br />

CNS<br />

Urogenital<br />

Lymphoma<br />

Breast, prostate<br />

Fraser Health N/A N/A Prostate<br />

CANCER Wai, Elaine Medicine Medicine UBC B.C. Cancer Agency N/A http://www.surgery.ubc.ca/faculty/<br />

ewai.html<br />

CANCER Wasan, Kishor Pharmaceutical<br />

<strong>Sciences</strong><br />

CANCER Watson, Peter<br />

H<br />

Microbiology/<br />

Biochemistry<br />

UBC UBC Campus kwasan@interchange.ubc.ca http://www.pharmacy.ubc.ca/<br />

faculty_staff/faculty/pharm_bio/<br />

pharm_bio_kishor_wasan.html<br />

UVic B.C. Cancer Agency<br />

Deeley Research<br />

Centre<br />

pwatson@bccancer.bc.ca http://www.bccrc.ca/drc/people_<br />

pwatson1.html<br />

Breast, lung<br />

Breast


182<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

CANCER Weinerman,<br />

Brian<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine Medicine UBC B.C. Cancer Agency bweinerm@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8502<br />

51913<br />

CANCER Weiss, Alan Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CANCER Wilson,<br />

Kenneth<br />

alan.weiss@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8510<br />

20528<br />

Medicine Medicine UBC B.C. Cancer Agency kwilson@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8690<br />

06119<br />

CANCER Yee, Adrian Medicine Medicine UBC B.C. Cancer Agency ayee@bccancer.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

010540<br />

CNS Beauchamp,<br />

Richard<br />

CNS Bjornson,<br />

Bruce<br />

Orthopedics Medicine UBC Child & Family<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

rbeauchamp@cw.bc.ca; beaucham@interchange.ubc.ca<br />

http://www.orthosurgery.ubc.ca/<br />

faculty_bios/beauchamp.html<br />

bbjornson@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=387<br />

Pancreas<br />

Liver<br />

Gastro-intestinal,<br />

melanoma<br />

Lymphoma<br />

Brain injury<br />

Stroke, epilepsy<br />

CNS Bozek, Chris Fraser Health N/A N/A Stroke<br />

ALS, inflammatory<br />

CNS Briemberg,<br />

Hannah<br />

medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Brown, Carl Surgery Medicine UBC Providence Health<br />

Care Research Institute/<br />

B.C. Cancer<br />

Agency<br />

CNS Cochrane,<br />

Doug<br />

Surgery Medicine UBC Child & Family<br />

Research Institute<br />

CNS Cole, Colm Anesthesia Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

hbriemberg@shaw.ca https://www.directory.ubc.ca/index.cf<br />

mupdate=yes&page=personDetail&r<br />

ow=1000006607<br />

cbrown@providencehealth.bc.ca http://www.providencehealthcare.org/<br />

colorectalsurgery/Carl-Brown.html<br />

dcochrane@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=26<br />

cole@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1469<br />

69188<br />

Colorectal, pain<br />

Pain


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

183<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CNS Collier, T. Neurology Interior Health<br />

Authority-Royal<br />

Inl<strong>and</strong> Hospital<br />

CNS Connolly,<br />

Mary<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

N/A N/A Stroke<br />

mconnolly@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=379<br />

CNS Curt, Armin Neurology Medicine UBC UBC Campus Armin.Curt@paralab.balgrist.ch http://www.neuroscience.uzh.ch/<br />

research/aging_disorders/curt<br />

CNS Dawson, Peter Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Devonshire,<br />

Virginia<br />

CNS Dhawan,<br />

Pankaj<br />

CNS Dvorak,<br />

Marcel<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Orthopedics Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Eisen, Andrew Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Farrell, Kevin Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CNS Feldman,<br />

Howard<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Fenwick, John Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

N/A N/A MS<br />

vdev@shaw.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51733<br />

Epilepsy/ seizures<br />

N/A N/A Brain injury<br />

vanspine@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=45184&_<br />

Type=Researchers-Database&_<br />

Title=Dvorak-Dr.-Marcel-F.<br />

eisen@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2149<br />

14754<br />

kfarrell@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=38<br />

hfeldman@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=130415&_<br />

Type=Researchers-Database&_<br />

Title=Feldman-Dr.-Howard-H.<br />

jfenwick@vanhosp.bc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=65490&_<br />

Type=Researchers-Database&_<br />

Title=Fenwick-Dr.-John<br />

SCI<br />

MS<br />

SCI<br />

MND<br />

Epilepsy/ seizures<br />

Alzheimer’s<br />

Brain injury, sepsis


184<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CNS Fisher, Charles Orthopedics Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Fleming,<br />

Jonathan<br />

CNS Friedman,<br />

Jan M.<br />

CNS Ganesan,<br />

Soma<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medical<br />

Genetics<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Gibson, Gillian Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Goumeniouk,<br />

Alex<strong>and</strong>er P.<br />

frid@interchange.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=43<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

CNS Hall, Wendy Nursing Applied Science<br />

CNS Hashimoto,<br />

Stanley<br />

CNS Hayden,<br />

Michael<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

vanspine@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=45360&_<br />

Type=Researchers-Database&_<br />

Title=Fisher-Dr.-Charles-G.<br />

fleming@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=43275&_<br />

Type=Researchers-Database&_<br />

Title=Fleming-Dr.-Jonathan<br />

soma.ganesan@vch.ca http://www.mhanet.ca/search/<br />

node/888<br />

gillian.gibson@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2667<br />

19405<br />

Medicine UBC UBC Campus dooley@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2823<br />

99151<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CMMT Medicine UBC Child & Family<br />

Research Institute<br />

UBC UBC Campus wendy.hall@nursing.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=373<br />

hashist@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=3172<br />

94272<br />

mrh@cmmt.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=54<br />

CNS Ho, Kennely Fraser Health N/A N/A Stroke<br />

SCI, brain<br />

Narcolepsy<br />

Mental health<br />

Schizophrenia<br />

Neuropathy<br />

Bipolar<br />

Cognitive<br />

MS<br />

Huntingdon’s


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

185<br />

DISEASE<br />

SPECIALTY<br />

CNS Hohl, Corinne<br />

M.<br />

CNS Honer,<br />

William<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Hooge, John Neurology Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Hrebicek, O Van Isl<strong>and</strong> Health<br />

Authority<br />

CNS Hsiung, Ging<br />

Yeuk [Robin]<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Innis, Sheila Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CNS Jacova,<br />

Claudia<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Jan, James Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CNS Janssen,<br />

Patricia<br />

CNS Javidan,<br />

Manouchehr<br />

Population &<br />

Public Health<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Neurology Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Jones, Michael Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Kastrukoff,<br />

Lorne<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

chohl@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1<br />

000014576; http://www.vchri.<br />

ca/s/IIFL_InvestigatorAbstracts.<br />

aspReportID=124905<br />

honer@interchange.ubc.ca http://www.neuroscience.ubc.ca/<br />

honer.htm<br />

jphooge@telus.net N/A MS<br />

Drug abuse<br />

Psychosis<br />

N/A N/A Neurology<br />

hsiung@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012208<br />

sinnis@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=61<br />

claudija@interchange.ubc.ca http://ubcneurology.com/Staff%20<br />

Web%20Pages/CJacova.html<br />

jjan@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/<br />

search_results.asp<br />

pjanssen@interchange.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=343<br />

manouchehr.javidan@vch.ca http://vch.eduhealth.ca/PDFs/FM/<br />

FM.470.V279.pdf<br />

michael.jones@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=3810<br />

89317<br />

lornefk@interchange.ubc.ca https://www.directory.ubc.ca/index.c<br />

fmpage=personDetail&row=390158<br />

974 http://www.chromos.com/about/<br />

exec/lornekastrukoff.htm<br />

Alzheimer’s<br />

Development, cystic<br />

fibrosis<br />

Alzheimer’s<br />

FASD<br />

Health<br />

Epilepsy/ seizures<br />

Epilepsy/ seizures<br />

MS, brain injury


186<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

CNS Kerns,<br />

Kimberly A<br />

CNS Kjernisted,<br />

Kevin<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Psychology UVic kkerns@uvic.ca http://web.uvic.ca/psyc/kerns.html FASD<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Kooy, J. Interior Health<br />

Authority<br />

CNS Krieger,<br />

Charles<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Kwon, Brian Orthopedics Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Lam,<br />

Raymond<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Lee, Chong Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Lu, Shao-Hua Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS MacEwan,<br />

William<br />

CNS McIntosh,<br />

Diane<br />

CNS McKeown,<br />

Martin J.<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

Neurology Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Misri, Shaila Psychiatry Medicine UBC Women's Health<br />

Research Institute/<br />

Child & Family<br />

Research Institute<br />

kevin.kjernisted@ubc.ca http://www.copemanhealthcare.com/<br />

medical-staff/dr.-kevin-kjernistedmd-frcpc<br />

Mental health<br />

N/A N/A Alzheimer's<br />

N/A https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=4198<br />

27513<br />

brian.kwon@vch.ca http://www.orthosurgery.ubc.ca/<br />

faculty_bios/kwon.html<br />

r.lam@ubc.ca http://www.crestbd.ca/researchers/<br />

lam-raymond.php<br />

ALS<br />

Neuropathy<br />

Depression<br />

N/A N/A Parkinson’s<br />

shao.lu@ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

54182<br />

Addiction<br />

Fraser Health N/A N/A Schizophrenia<br />

diane.mcintosh@ubc.ca http://www.copemanhealthcare.com/<br />

medical-staff/dr.-diane-mcintosh-mdfrcpc<br />

mmckeown@interchange.ubc.ca www.parkinsons.ubc.ca/Dr.MartinJ.<br />

McKeown.htm#Research<br />

shaila.misri@ubc.ca; smisri@<br />

providencehealth.bc.ca<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=5468<br />

02711<br />

CNS Newby, Br<strong>and</strong>i Fraser Health N/A N/A Pain<br />

CNS Nixon, Alan Fraser Health N/A N/A Pain<br />

Mental health<br />

Parkinson’s<br />

Depression


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

187<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CNS Novak, D. Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

CNS Oger, Joel Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Ong, May Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CNS Penn, Andrew Van Isl<strong>and</strong> Health<br />

Authority<br />

CNS Raymond,<br />

Lynn<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Redekop, Gary Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Rieckmann,<br />

Peter<br />

CNS Robinow, R.<br />

Oliver<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

N/A N/A Stroke<br />

joel.oger@ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=58855&_<br />

Type=Researchers-Database&_<br />

Title=Oger-Dr.-Joel-J-F<br />

dr.ong@telus.net https://www.directory.ubc.ca/index.c<br />

fmpage=personDetail&row=59768<br />

5024aspx<br />

karen.coles@viha.ca N/A Stroke, neurology<br />

lynnr@interchange.ubc.ca http://www.neuroscience.ubc.ca/<br />

raymond.htm<br />

gary.redekop@ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=39893&_<br />

Type=Researchers-Database&_<br />

Title=Redekop-Dr.-Gary-J.<br />

p.rieckmann@brain.ubc.ca http://www.ubcneurology.com/<br />

Staff%20Web%20Pages/PRieckmann.<br />

html<br />

richard.robinow@ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=6785<br />

43322<br />

MS<br />

Pain<br />

Huntingdon’s<br />

Neurosurgery,<br />

stroke<br />

CNS Rudnik, James Fraser Health N/A N/A Addiction, acute<br />

coronary syndrome<br />

CNS Sadovnick, A.<br />

Dessa<br />

Medical<br />

Genetics<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Schimmele, C UVic Van Isl<strong>and</strong> Health<br />

Authority<br />

CNS Singhal, Ash Surgery Medicine UBC Child & Family<br />

Research Institute<br />

sadovnik@infinet.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=6992<br />

95927<br />

MS<br />

Health<br />

Brain/CNS<br />

chrissch@uvic.ca N/A Mental health<br />

ash.singhal@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=384<br />

Brain injury


188<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CNS Steinbok, Paul Surgery Medicine UBC Child & Family<br />

Research Institute<br />

CNS Stoessl, A<br />

Jonathan<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Teal, Philip Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Thompson,<br />

Debbie<br />

CNS Thornton,<br />

Allen E<br />

CNS Townsend,<br />

Tiffany<br />

CNS Townson,<br />

Andrea<br />

CNS Traboulsee,<br />

Anthony<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

psteinbok@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=127<br />

jstoessl@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=39640&_<br />

Type=Researchers-Database&_<br />

Title=Stoessl-Dr.-A.-Jon<br />

teal@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=38022&_<br />

Type=Researchers-Database&_<br />

Title=Teal-Dr.-Philip-A.<br />

Brain injury<br />

Parkinson’s<br />

Stroke<br />

Fraser Health N/A N/A Depression<br />

Psychology SFU aethornt@sfu.ca http://www.sfu.ca/psyc/faculty/<br />

thorntona/<br />

Neurology Medicine UBC Van Coastal Health<br />

Research Institute<br />

Rehabilitation<br />

<strong>Sciences</strong><br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Tsui, Joseph Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Vorobeychik,<br />

Galina<br />

CNS Wambera,<br />

Kati<br />

Medicine Medicine UBC Fraser Health galina.vorobeychik@fraserhealth.ca<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

http://vch.eduhealth.ca/PDFs/FM/<br />

FM.470.V279.pdf<br />

atownson@vanhosp.bc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=65156&_<br />

Type=Researchers-Database&_<br />

Title=Townson-Dr.-Andrea-F.<br />

trabouls@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=62908&_<br />

Type=Researchers-Database&_<br />

Title=Traboulsee-Dr.-Anthony<br />

jtsui@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

005466<br />

Schizophrenia,<br />

cognitive<br />

Epilepsy<br />

SCI<br />

MS<br />

N/A MS<br />

Parkinson’s<br />

N/A N/A Brain/CNS


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

189<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CNS Weinerman, R Van Isl<strong>and</strong> Health<br />

Authority<br />

CNS Weiss,<br />

Margaret<br />

Psychiatry Medicine UBC Child & Family<br />

Research Institute<br />

CNS Williams, R Van Isl<strong>and</strong> Health<br />

Authority<br />

CNS Wong, Peter Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CNS Woolfenden,<br />

Andrew<br />

CNS Worsley,<br />

Daniel<br />

CNS Yatham,<br />

Lakshmi<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Radiology Medicine UBC Van Coastal Health<br />

Research Institute<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CNS Young, Allan Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

CRITICAL CARE Abu-Laban,<br />

Riyad<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

CRITICAL CARE Ayas, Najib Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CRITICAL CARE Chittock, Dean Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CRITICAL CARE Dhingra,<br />

Vinay<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

N/A N/A Psychiatry<br />

margaret.weiss@me.com http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=145<br />

Mental health<br />

N/A N/A Psychiatry<br />

pwong@interchange.ubc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=383<br />

Awoolf6175@aol.com https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001215<br />

dan.worsley@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8823<br />

80020<br />

yatham@interchange.ubc.ca http://www.crestbd.ca/researchers/<br />

yatham-lakshmi.php<br />

allan.young@ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

010214<br />

abulaban@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=61951&_<br />

Type=Researchers-Database&_<br />

Title=Abu-Laban-Dr.-Riyad-B<br />

najib.ayas@vch.ca http://ubc-sleepdisorders.vch.ca/ayas.<br />

htm<br />

dean.chittock@vch.ca http://www.biomedexperts.com/<br />

Profile.bme/234409/Dean_R_Chittock<br />

vinay.dhingra@vch.ca N/A<br />

Epilepsy/ seizures<br />

Stroke<br />

Stroke<br />

Bipolar<br />

Bipolar<br />

N/A<br />

Apnea<br />

Sepsis, thrombosis


190<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CRITICAL CARE Dodek, Peter Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CRITICAL CARE Dorscheid,<br />

Delbert<br />

Medicine Medicine -<br />

Critical Care<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UBC Providence Health<br />

Care Research<br />

Institute<br />

CRITICAL CARE Fenwick, John Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CRITICAL CARE Hameed, M. Interior Health<br />

Authority-Royal<br />

Inl<strong>and</strong> Hospital/<br />

Kelowna General<br />

Hospital<br />

CRITICAL CARE Henderson,<br />

William<br />

CRITICAL CARE Holmes-<br />

Boulton, C.<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute/<br />

Fraser Health<br />

Interior Health<br />

Authority<br />

pedodek@interchange.ubc.ca http://www.thecarenet.ca/index.<br />

phpoption=com_content&task=view<br />

&ID=29&Itemid=46<br />

ddorscheid@hli.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_del_dorscheid.shtml<br />

jfenwick@vanhosp.bc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=65490&_<br />

Type=Researchers-Database&_<br />

Title=Fenwick-Dr.-John<br />

N/A N/A<br />

william.henderson@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

011369<br />

N/A N/A<br />

CRITICAL CARE Keenan, Sean Medicine Medicine UBC Fraser Health sean_keenan@telus.net http://f1000medicine.com/<br />

member/2058229206155046<br />

CRITICAL CARE Reynolds,<br />

Steven<br />

Diabetes<br />

COPD, inflammatory,<br />

ARDS<br />

Brain injury, sepsis<br />

Inflammatory,<br />

trauma<br />

Septic shock, sepsis<br />

Medicine Medicine UBC Fraser Health sreynolds.md@gmail.com N/A Septic shock, ARDS<br />

CRITICAL CARE Ronco, Juan Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CRITICAL CARE Russell, James Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

jronco@vanhosp.bc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=65892&_<br />

Type=Researchers-Database&_<br />

Title=Ronco-Dr.-Juan-J.<br />

jrussell@providencehealth.bc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_james_russell.shtml<br />

ARDS<br />

Respiratory, sepsis


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

191<br />

DISEASE<br />

SPECIALTY<br />

CRITICAL CARE Skippen,<br />

Peter<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

pskippen@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=348<br />

CRITICAL CARE Sorokan, Todd Fraser Health N/A N/A Sepsis, pediatrics<br />

ARDS<br />

CRITICAL CARE Wensley,<br />

David<br />

CRITICAL CARE Winkler,<br />

Lawrence<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

General Internal<br />

Medicine<br />

Medicine UBC Van Isl<strong>and</strong> Health<br />

Authority- Nanaimo<br />

CRITICAL CARE Wood, G Van Isl<strong>and</strong> Health<br />

Authority<br />

CV / CARDIOLOGY Abel, James Cardiovascular<br />

Surgery<br />

CV / CARDIOLOGY Anis, Aslam Population &<br />

Public Health<br />

CV / CARDIOLOGY Ansley, David Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

CV / CARDIOLOGY Ashton,<br />

Thomas<br />

CV / CARDIOLOGY Auersperg,<br />

Edward<br />

Surgery UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine Medicine UBC Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

General Internal<br />

Medicine<br />

Medicine UBC Fraser Health<br />

Authority<br />

CV / CARDIOLOGY Aymong, Eve Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Bardal, Stan K Medical <strong>Sciences</strong><br />

dwensley@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8530<br />

18927<br />

drwink@shaw.ca www.drlwinkler.com<br />

Sepsis<br />

N/A N/A Intensive care<br />

jabel@providencehealth.bc.ca www.ctsnet.org/home/jabel Surgery<br />

aslam.anis@ubc.ca http://www.mhanet.ca/search/<br />

node/15<br />

david.ansley@vch.ca http://www.apt.ubc.ca/anesthesiology/Vancouver_General_Hospital/<br />

Department_Members/Dr_David_<br />

Ansley.htm<br />

Hypertension,<br />

obesity<br />

Coronary bypass<br />

N/A www.directory.ubc.ca/index.cfm Acute coronary<br />

syndrome<br />

e@auersperg.ca N/A<br />

eaymong@providencehealth.<br />

bc.ca<br />

http://www.biomedexperts.com/<br />

Profile.bme/63107/Eve_D_Aymong<br />

UVic bardals@uvic.ca http://www.zoominfo.com/people/<br />

Bardal_Stan_1207852047.aspx<br />

Acute coronary<br />

syndrome


192<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

CV / CARDIOLOGY Bernstein,<br />

Victoria<br />

CV / CARDIOLOGY Berringer,<br />

Ross<br />

CV / CARDIOLOGY Bondy,<br />

Gregory<br />

CV / CARDIOLOGY Bonet, Jorge<br />

Federico<br />

CV / CARDIOLOGY Bowering,<br />

John<br />

CV / CARDIOLOGY Buller,<br />

Christopher<br />

CV / CARDIOLOGY Carere,<br />

Ronald<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Surgery Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Pathology &<br />

Laboratory<br />

Med<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Anesthesia Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Cardiology Medicine UBC Van Coastal Health<br />

Research Institute<br />

Cardiology Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

dr.bernstein@telus.net http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=41888&_<br />

Type=Researchers-Database&_<br />

Title=Bernstein-Dr.-Victoria<br />

Acute coronary<br />

syndrome<br />

N/A N/A Coronary disease<br />

gbondy@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=717<br />

98641<br />

Cardiovascular<br />

disease, diabetes<br />

Fraser Health N/A N/A Cardiology<br />

jkbow@shaw.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=768<br />

71500<br />

cehbuller@shaw.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=41916&_<br />

Type=Researchers-Database&_<br />

Title=Buller-Dr.-Christopher-E.<br />

rcarere@providencehealth.bc.ca http://www.heart<strong>and</strong>lung.ca/roncarere/<br />

Hypertension<br />

Acute coronary<br />

syndrome<br />

Coronary artery<br />

disease<br />

CV / CARDIOLOGY Chan, Albert Fraser Health N/A N/A Coronary disease,<br />

stroke<br />

CV / CARDIOLOGY Chan, Sammy Cardiology Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Cheung,<br />

Anson<br />

CV / CARDIOLOGY Cheung,<br />

Stephen<br />

Surgery Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

schan@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

52746<br />

acheung@providencehealth.<br />

bc.ca<br />

http://www.providencehealthcare.org/<br />

heart_centre/pop_upA32AnsonCheung.html;<br />

http://www.surgery.ubc.<br />

ca/faculty/acheung.html<br />

Coronary artery<br />

disease, obesity<br />

Cardiovascular<br />

disease, surgery<br />

Fraser Health N/A N/A Acute coronary<br />

syndrome


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

193<br />

DISEASE<br />

SPECIALTY<br />

CV / CARDIOLOGY Chockalingam,<br />

Arum<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Health <strong>Sciences</strong><br />

CV / CARDIOLOGY Choi, Peter Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

CV / CARDIOLOGY Christenson,<br />

Jim<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

SFU achockal@sfu.ca www.fhs.sfu.ca/portal_memberdata/<br />

arun<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Surgery Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Clevel<strong>and</strong>, D. Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

CV / CARDIOLOGY Cogswell,<br />

Arthur<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CV / CARDIOLOGY Dawson, Keith Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Dunne, James<br />

V.<br />

CV / CARDIOLOGY Elliott,<br />

Thomas<br />

CV / CARDIOLOGY Ervin, Frank General Internal<br />

Medicine<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Fraser Health<br />

Authority<br />

CV / CARDIOLOGY Fradet, Guy Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Francis,<br />

Gordon<br />

CV / CARDIOLOGY Frohlich, Jiri Pathology &<br />

Laboratory<br />

Med<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PeterT.Choi@vch.ca http://www.apt.ubc.ca/anesthesiology/Vancouver_General_Hospital/Department_Members/Dr_Peter_Choi.<br />

htm<br />

Hypertension<br />

jimchris@interchange.ubc.ca N/A Myocardial infarction<br />

N/A N/A Acute coronary<br />

syndrome, atherosclerosis,<br />

atrial<br />

fibrillation<br />

acogswell@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

53861<br />

kdaw@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1777<br />

13788<br />

drjdunne@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2047<br />

69036<br />

tom.elliott@vch.ca; tgelliot@<br />

interchange.ubc.ca<br />

Cardiovascular<br />

disease<br />

Coronary disease<br />

Hypertension, GVHD<br />

http://drtomelliott.com/ Diabetes, cardiovascular<br />

disease<br />

flervin@telus.net N/A Acute coronary<br />

syndrome<br />

guy.fradet@ubc.ca http://www.surgery.ubc.ca/faculty/<br />

gfradet.html<br />

gfrancis@mrl.ubc.ca www.icapture.ubc.ca/who/who_bios_<br />

gordon_francis.shtml<br />

jifr@interchange.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_jiri_frolich.shtml<br />

Coronary bypass<br />

Cardiovascular<br />

disease<br />

Atherosclerosis,<br />

cholesteremia


194<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

CV / CARDIOLOGY Fung,<br />

Anthony Y-F.<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Gin, Kenneth Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Gordon,<br />

Wendy<br />

CV / CARDIOLOGY Halperin,<br />

Frank<br />

CV / CARDIOLOGY Hamburger,<br />

Jaap<br />

Medicine Medicine UBC Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

Medicine Medicine UBC Providence Health<br />

Care Research Institute,<br />

Van Coastal<br />

Health Research<br />

Institute<br />

CV / CARDIOLOGY Harris, Devin Medicine Medicine UBC Providence Health<br />

Care Research Institute,<br />

Van Coastal<br />

Health Research<br />

Institute<br />

CV / CARDIOLOGY Hayden,<br />

Robert<br />

CV / CARDIOLOGY Henderson,<br />

Mark<br />

CV / CARDIOLOGY Hill, John Pathology &<br />

Laboratory<br />

Med<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Hilton, Donald Van Isl<strong>and</strong> Health<br />

Authority -<br />

Cowichan District<br />

Hospital<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

funga@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2573<br />

42302<br />

kenneth.gin@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2697<br />

93865<br />

Fraser Health N/A N/A<br />

Acute coronary<br />

syndrome<br />

Cholesteremia,<br />

atherosclerosis,<br />

myocardial infarction<br />

N/A www.directory.ubc.ca/index.cfm Heart failure, acute<br />

coronary syndrome<br />

hamburge@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=65361&_<br />

Type=Researchers-Database&_<br />

Title=Hamburger-Dr.-Jaap-N.<br />

N/A http://www.sphemerg.ca/research/<br />

harris<br />

Atherosclerosis,<br />

coronary disease<br />

Myocardial infarction<br />

Fraser Health N/A N/A Cardiology<br />

Fraser Health N/A N/A Acute coronary<br />

syndrome<br />

jshill@interchange.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_john_hill.shtml<br />

Coronary disease<br />

N/A N/A Acute coronary<br />

syndrome


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

195<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CV / CARDIOLOGY Hsiang, York Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Human, Derek Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

CV / CARDIOLOGY Ignaszewski,<br />

Andrew<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Imrie, John Van Coastal Health-<br />

Lion's Gate Hospital<br />

CV / CARDIOLOGY Jamieson, Eric<br />

W.R.<br />

CV / CARDIOLOGY Johnston,<br />

Dean<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute/<br />

Providence Health<br />

Care Research<br />

Institute<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Jue, John C. Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Karim,<br />

Shahzad S.<br />

Surgery Medicine UBC Providence Health<br />

Care Research Institute/<br />

Fraser Health<br />

CV / CARDIOLOGY Kerr, Charles Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Kiess, Marla Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Kornder, Jan Fraser Health<br />

Authority-Surrey<br />

Memorial Hospital<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

yhsiang@vanhosp.bc.ca http://www.surgery.ubc.ca/faculty/<br />

yhsiang.html<br />

dhuman@cw.bc.ca http://www.bcchildrens.ca/Services/<br />

ChildrensHeartCentre/Healthcareteam/<br />

Leadershipteam.htm#human<br />

aignaszewski@providencehealth.bc.ca<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51017<br />

Cardiovascular<br />

disease<br />

Coronary disease<br />

Congestive heart<br />

failure, coronary<br />

disease<br />

N/A N/A Acute coronary<br />

syndrome<br />

eric.jamieson@ubc.ca http://www.providenceresearch.ca/<br />

directory/index.aspx<br />

dccj@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001176<br />

jjue@unixg.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=3833<br />

95162<br />

Shahzadk@shaw.ca http://www.surgery.ubc.ca/faculty/<br />

skarim.html<br />

ckerr@providencehealth.bc.ca http://www.providenceresearch.ca/<br />

directory/ResearcherDetail.aspx<br />

mkiess@providencehealth.bc.ca http://www.providenceresearch.ca/<br />

directory/index.aspx<br />

Cardiac surgery, cardiovascular<br />

disease,<br />

coronary bypass<br />

Atherosclerosis<br />

Coronary disease<br />

Coronary disease<br />

Coronary disease<br />

Hypertension<br />

Jan.Kornder@fraserhealth.ca N/A Acute coronary<br />

syndrome


196<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

CV / CARDIOLOGY Kuritzky,<br />

Robin<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Fraser Health N/A N/A Coronary disease<br />

CV / CARDIOLOGY Kwan, Susan Fraser Health N/A N/A Cardiology, diabetes<br />

CV / CARDIOLOGY Lai, Kevin Van Isl<strong>and</strong> Health<br />

Authority-Nanaimo<br />

Regional General<br />

Hospital<br />

CV / CARDIOLOGY Lear, Scott Biomedical<br />

Physiology<br />

SFU Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Leavitt, Blair CMMT Medicine UBC Child & Family<br />

Research Institute<br />

CV / CARDIOLOGY Lichtenstein,<br />

Samuel<br />

Cardiovascular<br />

Surgery<br />

Surgery UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Mancini, John Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Manyari,<br />

Dante<br />

CV / CARDIOLOGY Marsden,<br />

Julian<br />

Family<br />

Practice<br />

CV / CARDIOLOGY Martin, Mike Radiology Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Maung, Tun<br />

Zan<br />

N/A N/A Acute coronary<br />

syndrome<br />

salear@sfu.ca; slear@providencehealth.bc.ca<br />

www2.fas.sfu.ca/kin/Faculty.html;<br />

http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=281<br />

bleavitt@cmmt.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=40908&_<br />

Type=Researchers-Database&_<br />

Title=Leavitt-Dr.-Blair-R.<br />

slichtenstein@providencehealth.<br />

bc.ca<br />

www.ctsnet.org/home/slichtenstein Surgery<br />

mancini@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=63568&_<br />

Type=Researchers-Database&_<br />

Title=Mancini-Dr.-G.B.-John<br />

Obesity, coronary<br />

disease<br />

Genetic disease,<br />

coronary disease<br />

Cardiovascular<br />

disease<br />

Fraser Health N/A N/A Coronary disease<br />

Medicine UBC UBC Campus N/A http://www.bcpsqc.ca/celebratingachievements-in-bc/BCPSQC_Celebrating_Achievements_Marsden.htm<br />

m.l.martin@shaw.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

54357<br />

Congestive heart<br />

failure<br />

Cardiovascular<br />

disease<br />

Fraser Health N/A N/A Cardiology


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

197<br />

DISEASE<br />

SPECIALTY<br />

CV / CARDIOLOGY McDermid,<br />

Kevin<br />

CV / CARDIOLOGY McManus,<br />

Bruce<br />

CV / CARDIOLOGY Morris,<br />

Dorothy<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Pathology &<br />

Laboratory<br />

Med<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Fraser Health<br />

Authority-Langley<br />

Memorial Hospital<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Van Isl<strong>and</strong> Health<br />

Authority<br />

CV / CARDIOLOGY Moss, Robert Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Nadel, Helen Radiology Medicine UBC Child & Family<br />

Research Institute<br />

CV / CARDIOLOGY Orenstein<br />

Lyall, Teddi<br />

Lynn<br />

CV / CARDIOLOGY Pearce,<br />

Stephen, MD<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Penn, Andrew Van Isl<strong>and</strong> Health<br />

Authority<br />

CV / CARDIOLOGY Pistawka, K. Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

CV / CARDIOLOGY Polasek, P. Cardiology Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

CV / CARDIOLOGY Polasek, Petr Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

CV / CARDIOLOGY Priestman, B.<br />

Anne<br />

N/A N/A Acute coronary<br />

syndrome<br />

bmcmanus@mrl.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_bruce_mcmanus.shtml<br />

dorothy.morris@viha.ca N/A<br />

rmoss@providenceheallth.bc.ca www.heartcentre.ca/pop_up_RMoss.<br />

asp<br />

hnadel@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=5701<br />

68607<br />

Cardiovascular<br />

disease<br />

Transplant<br />

Coronary disease<br />

Orenstein@telus.net N/A Acute coronary<br />

syndrome<br />

Fraser Health N/A N/A Acute coronary<br />

syndrome<br />

karen.coles@viha.ca N/A Stroke, neurology<br />

N/A N/A Atrial fibrillation<br />

N/A N/A Acute coronary<br />

syndrome, atrial<br />

fibrillation<br />

N/A N/A Acute coronary<br />

syndrome<br />

Fraser Health N/A N/A Acute coronary<br />

syndrome


198<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CV / CARDIOLOGY Rabkin, Simon Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Ramanathan,<br />

Krishnan<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Reid, John Surgery Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Ricci, Donald Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Rosenberg,<br />

Frances<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

rabkin@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=43358&_<br />

Type=Researchers-Database&_<br />

Title=Rabkin-Dr.-Simon-W.<br />

kramanathan@providencehealth.bc.ca<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

011039<br />

Cholesteremia<br />

Acute coronary<br />

syndrome<br />

N/A N/A Coronary disease<br />

ricci@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=66053&_<br />

Type=Researchers-Database&_<br />

Title=Ricci-Dr.-Donald-R.<br />

Rosenbrg@providencehealth.<br />

bc.ca<br />

http://www.providenceresearch.ca/<br />

directory/index.aspx<br />

Acute coronary<br />

syndrome<br />

CV / CARDIOLOGY Rudnik, James Fraser Health N/A N/A Addiction, acute<br />

coronary syndrome<br />

CV / CARDIOLOGY Rupka, Dennis Fraser Health N/A N/A Acute coronary<br />

syndrome<br />

CV / CARDIOLOGY Sanatani,<br />

Shubhayan<br />

CV / CARDIOLOGY S<strong>and</strong>or,<br />

George<br />

CV / CARDIOLOGY Shariff,<br />

Salima<br />

CV / CARDIOLOGY Simkus,<br />

Gerald<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

ssanatani@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=114<br />

gs<strong>and</strong>or@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=115<br />

Coronary disease<br />

Fraser Health N/A N/A Cardiology<br />

Fraser Health N/A N/A Coronary disease


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

199<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CV / CARDIOLOGY Son, Wai Kon Fraser Health<br />

Authority-Chilliwack<br />

General Hospital<br />

CV / CARDIOLOGY Straatman,<br />

Lynn<br />

Pediatrics Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

N/A N/A Acute coronary<br />

syndrome<br />

lstraatman@providencehealth.<br />

bc.ca<br />

http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=296<br />

CV / CARDIOLOGY Tan, Peter Fraser Health N/A N/A Acute coronary<br />

syndrome<br />

CV / CARDIOLOGY Tsui, Winston General Internal<br />

Medicine<br />

CV / CARDIOLOGY Tung, Stanley Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Umedaly,<br />

Hamed<br />

Anesthesia Medicine UBC Van Coastal Health<br />

Research Institute<br />

Fraser Health N/A N/A<br />

stung@providencehealth.bc.ca http://www.providenceresearch.ca/<br />

directory/index.aspx<br />

hamed.umedaly@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8175<br />

85775<br />

CV / CARDIOLOGY Virani, Sean Medicine Medicine UBC UBC Campus N/A https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

014082<br />

CV / CARDIOLOGY Warriner,<br />

Brian<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Medicine UBC Providence Health<br />

Care Research Institute/<br />

Van Coastal<br />

Health Research<br />

Institute<br />

CV / CARDIOLOGY Webb, John Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Winkler,<br />

Lawrence<br />

CV / CARDIOLOGY Wong,<br />

Graham<br />

General Internal<br />

Medicine<br />

Medicine UBC Van Isl<strong>and</strong> Health<br />

Authority- Nanaimo<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

brian.warriner@vch.ca<br />

bwarrin@interchange.ubc.ca<br />

http://www.pharmacology.ubc.ca/<br />

FS%20sub%20dir/FS%20Warriner.<br />

html<br />

webb@providencehealth.bc.ca http://www.bccrc.ca/drc/people_<br />

jwebb.html<br />

drwink@shaw.ca www.drlwinkler.com<br />

gcwong@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

006503<br />

Coronary disease<br />

Coronary bypass<br />

Coronary disease<br />

Palliative care, cardiac<br />

surgery, pain<br />

Coronary bypass,<br />

myocardial infarction,<br />

cardiac surgery,<br />

angioplasty/<br />

stent<br />

Acute coronary<br />

syndrome


200<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

CV / CARDIOLOGY Ye, Jian Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

CV / CARDIOLOGY Yeung-Lai-<br />

Wah, John<br />

Cardiology Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

CV / CARDIOLOGY Dyck, Chad Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

DENTAL Brunette,<br />

Donald<br />

DENTAL Imai, Pauline<br />

H.<br />

DENTAL MacEntee,<br />

Michael<br />

DENTAL Putnins,<br />

Edward<br />

DENTAL Wyatt,<br />

Christopher<br />

DERMATOLOGY Briemberg,<br />

Hannah<br />

Oral Biological<br />

& Medical SCI<br />

Oral Biological<br />

& Medical SCI<br />

Oral Health<br />

<strong>Sciences</strong><br />

Oral Biological<br />

& Medical SCI<br />

Oral Health<br />

<strong>Sciences</strong><br />

DERMATOLOGY Dutz, Jan Dermatology<br />

& Skin Science<br />

DERMATOLOGY Ho, Vincent Medicine/<br />

Dermatology<br />

& Skin Science<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

jye@providencehealth.bc.ca http://www.surgery.ubc.ca/faculty/<br />

jye.html<br />

jayeung@axion.net http://www.providenceresearch.ca/<br />

directory/index.aspx<br />

N/A N/A<br />

Dentistry UBC UBC Campus brunette@interchange.ubc.ca http://www.dentistry.ubc.ca/research/<br />

brunette.html<br />

Dentistry UBC UBC Campus pauline.imai@hotmail.com https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

011342<br />

Dentistry UBC UBC Campus macentee@interchange.ubc.ca http://www.elders.dentistry.ubc.ca/<br />

research/our_people/macentee.asp<br />

Dentistry UBC UBC Campus putnins@interchange.ubc.ca http://www.dentistry.ubc.ca/research/<br />

PeriodontalBiology/putnins.asp<br />

Dentistry UBC UBC Campus cwyatt@interchange.ubc.ca http://www.prosthodontist.ca/about.<br />

html<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

hbriemberg@shaw.ca https://www.directory.ubc.ca/index.cf<br />

mupdate=yes&page=personDetail&r<br />

ow=1000006607<br />

dutz@interchange.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=35<br />

vho@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=66518&_<br />

Type=Researchers-Database&_<br />

Title=Ho-Dr.-Vincent-C. http://www.<br />

skincarecentre.ca/about_us/doctors/<br />

vincent_ho.htm<br />

Cardiac surgery<br />

Coronary disease<br />

Hygiene<br />

Implants<br />

Hygiene<br />

Hygiene<br />

ALS, inflammatory<br />

Inflammatory<br />

Psoriasis


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

201<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

DERMATOLOGY Lui, Harvey Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

DERMATOLOGY Marra, Carlo Pharmaceutical<br />

<strong>Sciences</strong><br />

DERMATOLOGY Prendiville,<br />

Julie<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UBC Van Coastal Health<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

DERMATOLOGY Rivers, Jason Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

DERMATOLOGY Shapiro, Jerry Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

DERMATOLOGY Zhou, Youwen Dermatology<br />

& Skin Science<br />

EMERGENCY<br />

MEDICINE<br />

EMERGENCY<br />

MEDICINE<br />

EMERGENCY<br />

MEDICINE<br />

EMERGENCY<br />

MEDICINE<br />

Abu-Laban,<br />

Riyad<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

Grafstein, Eric Surgery UBC Providence Health<br />

Care Research<br />

Institute<br />

Harris, Devin Medicine Medicine UBC Providence Health<br />

Care Research Institute,<br />

Van Coastal<br />

Health Research<br />

Institute<br />

Goldman, Ran Pediatrics UBC Child & Family<br />

Research Institute<br />

harvey.lui@ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=68599&_<br />

Type=Researchers-Database&_<br />

Title=Lui-Dr.-Harvey<br />

Carlo.marra@ubc.ca www.pharmacy.ubc.ca/faculty_staff/<br />

faculty/practice/practice_carlo_marra.<br />

html<br />

jprendiville@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=6447<br />

24262<br />

N/A http://www.dermatology.ca/find_<br />

derm/profiles/jason_k_rivers.html<br />

shapiro@interchange.ubc.ca http://www.skincarecentre.ca/about_<br />

us/doctors/jerry_shapiro.htm<br />

ywzhou@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=59990&_<br />

Type=Researchers-Database&_<br />

Title=Zhou-Dr.-Youwen<br />

abulaban@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=61951&_<br />

Type=Researchers-Database&_<br />

Title=Abu-Laban-Dr.-Riyad-B<br />

egrafstein@providencehealth.<br />

bc.ca<br />

http://www.sphemerg.ca/research/<br />

grafstein<br />

N/A http://www.sphemerg.ca/research/<br />

harris<br />

rgoldman@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=273<br />

Psoriasis<br />

Arthritis, psoriasis<br />

Psoriasis<br />

Inflammatory,<br />

psoriasis<br />

Alopecia, psoriasis<br />

Endocrinology<br />

N/a<br />

Hepatitis<br />

Myocardial infarction<br />

Pediatrics


202<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

EMERGENCY<br />

MEDICINE<br />

EMERGENCY<br />

MEDICINE<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

kjacobson@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=62<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Hohl, Corinne<br />

M.<br />

Stenstrom,<br />

Robert<br />

Anderson,<br />

Frank H<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

Family<br />

Practice<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Behrens, C Van Isl<strong>and</strong> Health<br />

Authority<br />

Byrne,<br />

Michael<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Daly, D Van Isl<strong>and</strong> Health<br />

Authority<br />

Dickson, G.<br />

Brentley<br />

Family<br />

Practice<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Enns, Rob Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Gray, James Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Jacobson,<br />

Kevan<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Person, D Van Isl<strong>and</strong> Health<br />

Authority<br />

Petrunia,<br />

Dennis<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Van Isl<strong>and</strong> Health<br />

Authority<br />

chohl@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1<br />

000014576; http://www.vchri.<br />

ca/s/IIFL_InvestigatorAbstracts.<br />

aspReportID=124905<br />

robstenstrom@shaw.ca http://www.sphemerg.ca/research/<br />

stenstrom<br />

franka@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=150<br />

74854<br />

N/A N/A<br />

michael.byrne@vch.ca N/A<br />

N/A N/A<br />

N/A N/A<br />

renns@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001168<br />

allgray@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2885<br />

48071<br />

N/A N/A<br />

N/A N/A<br />

Drug abuse<br />

Asthma<br />

Colitis, Crohn's,<br />

hepatitis<br />

Crohn’s, colitis,<br />

esophageal/<br />

stomach<br />

Colitis, esophageal/<br />

stomach<br />

Crohn’s


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

203<br />

DISEASE<br />

SPECIALTY<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

rschreiber@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=118<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

GASTRO-INTES-<br />

TINAL<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Phang,<br />

Terence<br />

Surgery Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

tphang@providencehealth.bc.ca http://www.bccancer.bc.ca/NR/<br />

exeres/C5D9B877-6E87-456B-B5FA-<br />

CF9BEEFC863E.htm<br />

Pluta, Henryk Fraser Health N/A N/A Gastro-enterology<br />

Prest, Marcia Fraser Health N/A N/A Gastro-enterology<br />

Raval, Manoj<br />

J.<br />

Schreiber,<br />

Richard<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Singh, RA Van Isl<strong>and</strong> Health<br />

Authority<br />

Steiner,<br />

Theodore<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Weiss, Alan Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Yoshida, Eric Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

GENITOURINARY Black, Peter Urologic <strong>Sciences</strong><br />

GENITOURINARY Carpenito,<br />

Gerardo<br />

GENITOURINARY Chew, Ben Urologic <strong>Sciences</strong><br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

mraval@providencehealth.bc.ca http://www.providencehealthcare.org/<br />

colorectalsurgery/Manoj-Raval.html<br />

N/A N/A<br />

tsteiner@interchange.ubc.ca http://www.ID.med.ubc.ca/Faculty/<br />

Faculty_Steiner.htm<br />

alan.weiss@vch.ca https://www.directory.ubc.ca/index.cf<br />

mpage=personDetail&row=8510205<br />

28 http://www.cedarproject.ca/pages/<br />

A5_11yoshida.html; https://www.<br />

directory.ubc.ca/index.cfmpage=pers<br />

onDetail&row=899751745<br />

eric.yoshida@vch.ca www.prostatecentre.com/aboutus/<br />

aboutus.phppageID=187<br />

Colitis<br />

Motility<br />

Liver disease<br />

IBD<br />

Liver<br />

Hepatitis<br />

N/A N/A Bladder cancer<br />

Fraser Health N/A www.prostatecentre.com/aboutus/<br />

aboutus.phppageID=178<br />

ben.chew@ubc.ca http://www.prostatecentre.com/aboutus/aboutus.phppageID=166<br />

Nephrology<br />

Renal


204<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

GENITOURINARY Chi, Kim Oncology Medicine UBC B.C. Cancer Agency kchi@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1332<br />

87841<br />

GENITOURINARY Chiu, Anthony Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

GENITOURINARY Cooper, S. Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

GENITOURINARY Daroza,<br />

Gerald<br />

GENITOURINARY Davison, Joyce Nursing UBC Van Coastal Health<br />

Research Institute<br />

GENITOURINARY Duncan, John<br />

A.<br />

GENITOURINARY Fenster,<br />

Howard<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Urologic <strong>Sciences</strong><br />

Medicine UBC Van Coastal Health<br />

Res Inst<br />

GENITOURINARY Gill, John Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

GENITOURINARY Gleave,<br />

Martin<br />

GENITOURINARY Goldenberg,<br />

Larry<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

GENITOURINARY Horgan, K Van Isl<strong>and</strong> Health<br />

Authority<br />

GENITOURINARY Jastrzebski,<br />

Jacek<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Prostate<br />

antchiu@shaw.ca N/A Renal<br />

N/A N/A Renal<br />

Fraser Health N/A Renal<br />

joyce.davison@vch.ca www.prostatecentre.com/aboutus/<br />

aboutus.phppageID=158<br />

john.duncan@shaw.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=41711&_<br />

Type=Researchers-Database&_<br />

Title=Duncan-Dr.-John-A<br />

Prostate cancer<br />

Renal<br />

N/A http://urology.ubc.ca/faculty Bladder<br />

jgill@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

006603<br />

gleave@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=63578&_<br />

Type=Researchers-Database&_<br />

Title=Gleave-Dr.-Martin-E.<br />

research@vanhosp.bc.ca http://www.prostatecentre.com/aboutus/aboutus.phppageID=118<br />

Renal<br />

Prostate<br />

Prostate<br />

N/A N/A Nephrology<br />

jjastrze@vanhosp.bc.ca N/A Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

205<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

GENITOURINARY Jones, C Van Isl<strong>and</strong> Health<br />

Authority<br />

GENITOURINARY Jung, Beverly Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

GENITOURINARY Horgan, K Van Isl<strong>and</strong> Health<br />

Authority<br />

GENITOURINARY Jastrzebski,<br />

Jacek<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

GENITOURINARY Jones, C Van Isl<strong>and</strong> Health<br />

Authority<br />

GENITOURINARY Jung, Beverly Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

GENITOURINARY Karim,<br />

Mohamud<br />

GENITOURINARY Keown, Paul Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

GENITOURINARY Kollmannsberger,<br />

Christian<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

N/A N/A Nephrology<br />

bjung@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

006604<br />

Renal<br />

N/A N/A Nephrology<br />

jjastrze@vanhosp.bc.ca N/A Renal<br />

N/A N/A Nephrology<br />

bjung@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

006604<br />

Renal<br />

Fraser Health N/A N/A Renal<br />

UBC B.C. Cancer Agency ckollmannsberger@bccancer.<br />

bc.ca<br />

keown@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=66522&_<br />

Type=Researchers-Database&_<br />

Title=Keown-Dr.-Paul-A.<br />

http://www.bccrc.ca/at/people_ckollmannsberger.html<br />

Renal<br />

Colorectal, kidney,<br />

gastro-intestinal,<br />

urogenital, liver<br />

GENITOURINARY Lam, George Fraser Health N/A N/A Nephrology<br />

Dialysis, renal<br />

GENITOURINARY Levin, Adeera Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

GENITOURINARY Matsuda-<br />

Abedini, Mina<br />

GENITOURINARY Nguan, Chris Urologic <strong>Sciences</strong><br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

alevin@providencehealth.bc.ca http://www.krescent.ca/Page.<br />

aspxpid=755<br />

mmatsuda@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012350<br />

chris@nguan.ca www.med.ubc.ca/research/rm/<br />

rm_urologic.htm<br />

Renal<br />

Transplant


206<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

GENITOURINARY Nigro, Mark Urologic <strong>Sciences</strong><br />

GENITOURINARY Paterson,<br />

Ryan<br />

Urologic <strong>Sciences</strong><br />

GENITOURINARY So, Alan Urologic <strong>Sciences</strong><br />

GENITOURINARY Steinhoff,<br />

Gary<br />

GENITOURINARY Stevenson,<br />

Ron<br />

GENITOURINARY Stothers, Lynn Urologic <strong>Sciences</strong><br />

Medicine UBC Van Coastal Health<br />

Res Inst<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

B.C. Cancer Agency,<br />

Van Isl<strong>and</strong> Health<br />

Authority<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

GENITOURINARY Taylor, Paul Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

GENITOURINARY Tucker, Lori Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

GENITOURINARY White, Colin Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

GENITOURINARY Wijeyesinghe,<br />

ECR<br />

GENITOURINARY Yeung, Choi<br />

Kit<br />

Kidney Clinic Interior Health<br />

Authority-Royal<br />

Inl<strong>and</strong> Hospital<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

nigro@interchange.ubc.ca N/A Bladder<br />

paterson@interchange.ubc.ca http://urology.ubc.ca/wp-content/<br />

uploads/2007/02/paterson-ryan.pdf<br />

alan.so@vch.ca http://www.prostatecentre.com/aboutus/aboutus.phppageID=148<br />

N/A www.bccancer.bc.ca/NR/<br />

exeres/014CD3CD-7811-4014-B067-<br />

A817EB955FB2.htm<br />

ronald.stevenson@ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51988<br />

lynns@interchange.ubc.ca http://urology.ubc.ca/wp-content/<br />

uploads/2007/02/Stothers-L.pdf<br />

ptaylor@providencehealth.bc.ca https://www.directory.ubc.ca/index.cf<br />

mpage=personDetail&row=7872254<br />

83; http://www.providenceresearch.<br />

ca/directory/index.aspx<br />

ltucker@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=134<br />

cwhite@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=247<br />

Kidney, prostate<br />

Prostate<br />

Prostate, bladder<br />

Male urogenital<br />

Bladder<br />

Dialysis<br />

Renal<br />

N/A N/A Renal<br />

cyeung@vanhosp.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8900<br />

66170<br />

Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

207<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

GENITOURINARY Forzley, Brian Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

HEMATOLOGY Du Plessis, J. Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

HEMATOLOGY Kiaii,<br />

Mercedeh<br />

HEMATOLOGY Lam, Wendy Oncology/<br />

Hematology<br />

HEMATOLOGY Leitch,<br />

Heather<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Fraser Health<br />

Authority-Burnaby<br />

Hospital<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

HEMATOLOGY Nevill, Thomas Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

HEMATOLOGY Schultz, Kirk Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

HEMATOLOGY Shereck, Evan<br />

B.<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

HEMATOLOGY Toze, Cynthia Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

HEMATOLOGY Tsang, Peter Medicine Medicine UBC Child & Family<br />

Research Institute<br />

HEMATOLOGY Vickars, Linda<br />

M.<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

N/A N/A Nephrology<br />

N/A N/A Orthopedics<br />

mkiaii@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

003484<br />

Thrombosis/ coagulation,<br />

anemia<br />

wylam@telus.net N/A Multiple myeloma,<br />

metastatic, breast,<br />

lung, idiopathic<br />

thrombocytic<br />

purpura<br />

hleitch@providencehematology.<br />

com<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012134<br />

tnevill@bccancer.bc.ca http://www.canadianhematologysociety.org/exec_tomnevill.htm<br />

kschultz@interchange.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=119<br />

eshereck@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=295<br />

ctoze@bccancer.bc.ca http://www.leukemiabmtprogram.<br />

org/general_information/about_us/<br />

our_doctors/toze.html<br />

ptsang@bccancer.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001205<br />

Thrombosis/ coagulation<br />

lvickars@providencehematology.com<br />

http://www.cbr.ubc.ca/research_lvickars.htm<br />

Leukemia, myeloma<br />

Leukemia, thrombocytopenia<br />

Leukemia, GVHD<br />

Lymphoma<br />

Thrombosis/ coagulation,<br />

myelodysplastic<br />

syndromes


208<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

HEMATOLOGY Wu, John K. Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

ID/ INFECTION Alimenti,<br />

Ariane<br />

ID/ INFECTION Anderson,<br />

Frank H<br />

ID/ INFECTION Brunstein,<br />

John<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Biochemistry<br />

& Molec<br />

Biology<br />

ID/ INFECTION Burdge, David Infectious<br />

Diseases<br />

ID/ INFECTION Coldman,<br />

Andrew<br />

Population &<br />

Public Health<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

ID/ INFECTION Conway, Brian Anesthesia Medicine UBC Van Coastal Health<br />

Research Institute/<br />

Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Dewet, Joseph Family<br />

Practice<br />

ID/ INFECTION Dobson,<br />

Simon<br />

ID/ INFECTION Elwood,<br />

Richard Kevin<br />

ID/ INFECTION Filiatrault,<br />

Lyne<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

jwu@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=249<br />

aalimenti@cw.bc.ca N/A HIV<br />

franka@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=150<br />

74854<br />

jbrunstein@cw.bc.ca http://www.pathology.ubc.ca/New-<br />

Pathology/<strong>Clinical</strong>AssistantProfessor/<br />

John_Brunstein.html<br />

dburdge@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=257<br />

Medicine UBC B.C. Cancer Agency acoldman@bccancer.bc.ca http://www.stat.ubc.ca/People/Home/<br />

index.phpperson=:coldman:<br />

bconway@interchange.ubc.ca http://www.mhanet.ca/search/<br />

node/35<br />

Medicine UBC UBC Campus N/A N/A HIV<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC BC Centre for<br />

Disease Control<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

sdobson@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51085<br />

kevin.elwood@bccdc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=2198<br />

33890<br />

Genetic disease, infection,<br />

thrombosis/<br />

coagulation<br />

Colitis, Crohn’s,<br />

hepatitis<br />

Respiratory<br />

HIV<br />

HPV<br />

Hepatitis, HIV<br />

N/A N/A Wound<br />

Hepatitis, HPV, HSV,<br />

meningitis<br />

TB


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

209<br />

DISEASE<br />

SPECIALTY<br />

ID/ INFECTION Fischer,<br />

Benedikt<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Health <strong>Sciences</strong><br />

ID/ INFECTION Forbes, John Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

ID/ INFECTION Grafstein, Eric Surgery UBC Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Harder, Curtis Van Isl<strong>and</strong> Health<br />

Authority<br />

ID/ INFECTION Hogg, Robert Population &<br />

Public Health/<br />

Health <strong>Sciences</strong><br />

ID/ INFECTION Hu, Joan Statistics &<br />

Actuarial<br />

Science<br />

ID/ INFECTION Joffres, Michel Health <strong>Sciences</strong><br />

Medicine UBC/<br />

SFU<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

SFU bfa11@sfu.ca www.fhs.sfu.ca/portal_memberdata/<br />

bfischer<br />

Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Kibsey, P Van Isl<strong>and</strong> Health<br />

Authority<br />

ID/ INFECTION Krajden, Mel <strong>Clinical</strong> <strong>Trials</strong> Medicine UBC Provincial Health<br />

Services Authority<br />

Labs<br />

ID/ INFECTION Kwan, Peter Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

ID/ INFECTION Lakhani,<br />

Anisha<br />

jforbes@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=41<br />

egrafstein@providencehealth.<br />

bc.ca<br />

http://www.sphemerg.ca/research/<br />

grafstein<br />

Infection<br />

HIV<br />

Hepatitis<br />

curtis.harder@viha.ca N/A Microbiology,<br />

pharmacy<br />

robert_hogg@sfu.ca www.fhs.sfu.ca/portal_memberdata/<br />

rhogg<br />

SFU joanh@stat.sfu.ca http://www.stat.sfu.ca/~joanh/ HIV<br />

SFU mjoffres@sfu.ca www.fhs.sfu.ca/portal_memberdata/<br />

mjoffres<br />

HIV/AIDS<br />

N/A N/A Microbiology<br />

mel.krajden@bccdc.ca www.cdc.ubc.ca/People/MelKrajden.<br />

htm<br />

pwkwan@gmail.com https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=4241<br />

31757<br />

Fraser Health N/A N/A<br />

ID/ INFECTION Lavoie, Julye B.C. Cancer Agency jlavoie@bccancer.bc.ca N/A CMV<br />

Herpes, respiratory<br />

ID/ INFECTION McElhaney,<br />

Janet<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

janet.mcelhaney@ubc.ca http://www.ID.med.ubc.ca/Faculty/Associate_Members/Janet_McElhaney.<br />

htm<br />

HIV<br />

HPV<br />

HPV


210<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

ID/ INFECTION Mirzanejad,<br />

Yazdan<br />

ID/ INFECTION Money,<br />

Deborah<br />

ID/ INFECTION Montaner,<br />

Julio<br />

ID/ INFECTION Montessori,<br />

Valentina<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Women's Health<br />

Research Institute<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Ochnio, Jan Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

ID/ INFECTION Papp,<br />

Anthony<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

ID/ INFECTION Petric, Martin Medicine UBC Provincial Health<br />

Services Authority<br />

Labs<br />

ID/ INFECTION Phillips,<br />

Elizabeth<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Phillips, Peter Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Fraser Health N/A N/A Diarrhea, diabetes<br />

dmoney@cw.bc.ca http://www.whri.org/projects<strong>and</strong>people/people/Money.htm<br />

jmontaner@cfenet.ubc.ca http://www.cmeonhiv.com/pub/dr..<br />

julio.montaner.php<br />

vmontessori@cfenet.ubc.ca http://www.cmeonhiv.com/pub/dr..<br />

valentina.montessori.php<br />

jochnio@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

54518<br />

anthony.papp@ubc.ca http://www.surgery.ubc.ca/faculty/<br />

apapp.html<br />

martin.petric@bccdc.ca http://www.cdc.ubc.ca/People/Martin-<br />

Petric.htm<br />

ephillips@cfenet.ubc.ca N/A HIV<br />

pphillips@cfenet.ubc.ca http://www.ID.med.ubc.ca/Faculty/<br />

Peter_Phillips.htm<br />

ID/ INFECTION Pick, Neora Medicine Medicine UBC UBC Campus npick@cw.bc.ca http://www.whri.org/projects<strong>and</strong>people/people/Pick.htm<br />

ID/ INFECTION Power, Maryse Medicine Medicine UBC B.C. Cancer Agency N/A http://www.leukemiabmtprogram.<br />

org/general_information/about_us/<br />

our_doctors/power.html<br />

ID/ INFECTION Rekart,<br />

Michael<br />

Centre for Disease<br />

Control<br />

Medicine UBC BC Centre for<br />

Disease Control<br />

michael.rekart@bccdc.ca http://www.cdc.ubc.ca/People/MichaelRekart.htm<br />

HPV, pregnancy<br />

HIV<br />

HIV<br />

Hepatitis<br />

Infection<br />

Respiratory<br />

HIV<br />

HIV<br />

Fungal<br />

HIV


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

211<br />

DISEASE<br />

SPECIALTY<br />

ID/ INFECTION Reynolds,<br />

Steven<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

ID/ INFECTION Romney, Marc Pathology &<br />

Laboratory<br />

Med<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine Medicine UBC Fraser Health sreynolds.md@gmail.com N/A Septic shock, ARDS<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Russell, James Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Schechter,<br />

Martin<br />

ID/ INFECTION Scheifele,<br />

David<br />

ID/ INFECTION Skowronski,<br />

Danuta<br />

Health Care/<br />

Epidemiology,<br />

Population &<br />

Public Health<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Centre for Disease<br />

Control<br />

Medicine UBC BC Centre for<br />

Disease Control<br />

ID/ INFECTION Stark, Donald Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Stiver, Grant Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

ID/ INFECTION Synnes, Anne Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

ID/ INFECTION Tyndall, Mark Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

ID/ INFECTION Wong,<br />

Christopher<br />

ID/ INFECTION Yoshida, Eric Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

mromney@providencehealth.<br />

bc.ca<br />

http://www.pathology.ubc.ca/New-<br />

Pathology/<strong>Clinical</strong>AssistantProfessor/<br />

Marc_Romney.html<br />

jrussell@providencehealth.bc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_james_russell.shtml<br />

Martin.schechter@ubc.ca http://www.providenceresearch.ca/<br />

directory/index.aspx<br />

dscheifele@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=117<br />

danuta.skowronski@bccdc.ca http://www.cdc.ubc.ca/People/DanutaSkowronski.htm<br />

dstark@interchange.ubc.ca http://www.allergyfoundation.ca/<br />

website/donald_stark.html<br />

gstiver@interchange.ubc.ca http://www.ID.med.ubc.ca/Faculty/<br />

Dr__Grant_Stiver.htm<br />

asynnes@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=129<br />

mtyndall@cfenet.ubc.ca http://www.cmeonhiv.com/pub/dr..<br />

mark.tyndall.php<br />

Infection<br />

Respiratory, sepsis<br />

HIV<br />

DTP, influenza,<br />

MMR, pneumococcal<br />

DTP, influenza<br />

Infection<br />

Infection<br />

Fungal<br />

Fraser Health N/A N/A Diarrhea<br />

eric.yoshida@vch.ca http://www.cedarproject.ca/pages/<br />

A5_11yoshida.html https://www.<br />

directory.ubc.ca/index.cfmpage=pers<br />

onDetail&row=899751745<br />

HIV<br />

Hepatitis


212<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

ID/ INFECTION Yuen, Anna Fraser Health N/A N/A<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

Amed,<br />

Shazhan<br />

Anis, Aslam Population &<br />

Public Health<br />

Begg, Iain Ophthalmology<br />

& Visual<br />

Science<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

UBC Van Coastal Health<br />

Research Institute<br />

Bennett, Mary Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Bondy,<br />

Gregory<br />

Pathology &<br />

Laboratory<br />

Med<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Chan, Sammy Cardiology Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Chanoine,<br />

Jean-Pierre<br />

Chapman,<br />

Kristine<br />

Clarke, Lorne Medical<br />

Genetics<br />

Duncan, John<br />

A.<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

samed@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=305<br />

aslam.anis@ubc.ca http://www.mhanet.ca/search/<br />

node/15<br />

begg@portal.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=518<br />

14651<br />

mbennett@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51067<br />

gbondy@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=717<br />

98641<br />

schan@providencehealth.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

52746<br />

jchanoine@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=20<br />

kristinechapman@shaw.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

011048<br />

lclarke@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=24<br />

john.duncan@shaw.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=41711&_<br />

Type=Researchers-Database&_<br />

Title=Duncan-Dr.-John-A<br />

Diabetes<br />

Hypertension,<br />

obesity<br />

Diabetes<br />

Endocrinology<br />

Cardiovascular<br />

disease, diabetes<br />

Coronary artery<br />

disease, obesity<br />

Growth<br />

Diabetes<br />

Genetic disease<br />

Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

213<br />

DISEASE<br />

SPECIALTY<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Elliott,<br />

Thomas<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

tom.elliott@vch.ca<br />

tgelliot@interchange.ubc.ca<br />

http://drtomelliott.com/ Diabetes, cardiovascular<br />

disease<br />

Kwan, Susan Fraser Health N/A N/A Cardiology, diabetes<br />

Lear, Scott Biomedical<br />

Physiology<br />

SFU Providence Health<br />

Care Research<br />

Institute<br />

Leavitt, Blair CMMT Medicine UBC Child & Family<br />

Research Institute<br />

Leung, A. Interior Health<br />

Authority-Royal<br />

Inl<strong>and</strong> Hospital<br />

Matsell,<br />

Douglas<br />

Meneilly,<br />

Graydon<br />

Metzger,<br />

Daniel<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Miller, D Van Isl<strong>and</strong> Health<br />

Authority<br />

Mirzanejad,<br />

Yazdan<br />

dmetzger@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=91<br />

Panagiotopoulos,<br />

Dina<br />

Salvarinova,<br />

Ramona<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

salear@sfu.ca; slear@providencehealth.bc.ca<br />

www2.fas.sfu.ca/kin/Faculty.html;<br />

http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=281<br />

bleavitt@cmmt.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=40908&_<br />

Type=Researchers-Database&_<br />

Title=Leavitt-Dr.-Blair-R.<br />

Obesity, coronary<br />

disease<br />

Genetic disease,<br />

coronary disease<br />

N/A N/A Diabetes<br />

dmatsell@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=89<br />

graydon.meneilly@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

008929<br />

Growth<br />

Diabetes<br />

Diabetes<br />

N/A N/A Endocrinology<br />

Fraser Health N/A N/A Diarrhea, diabetes<br />

dpanagiotopoulos@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=103<br />

rsalvari@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

015300<br />

Diabetes<br />

Genetic disease


214<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

METABOLIC/<br />

ENDOCRINE<br />

Pediatrics Medicine UBC UBC Campus sstockler@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=255<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Sirrs, S<strong>and</strong>ra Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Stewart,<br />

Laura<br />

Stockler,<br />

Sylvia<br />

Studney,<br />

Donald<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

s<strong>and</strong>ra.sirrs@vch.ca http://www.cyhrnet.ca/members/<br />

node/3576<br />

lstewart@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51150<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Tomlin, D. Interior Health<br />

Authority-Kootenay<br />

Lake Hospital<br />

Ur, Ehud Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

N/A https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7729<br />

29244<br />

Genetic disease<br />

Genetic disease<br />

Genetic disease<br />

Diabetes<br />

N/A N/A Diabetes<br />

ehud.ur@vch.ca www.obesitynetwork.ca/members/view.<br />

aspxID=336&title=Ehud+Ur<br />

Yang, Tung Medicine Medicine UBC UBC Campus tc_yang@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012839<br />

Zhou, Youwen Dermatology<br />

& Skin Science<br />

Backman,<br />

Catherine<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

UBC Van Isl<strong>and</strong> Health<br />

Authority- Nanaimo,<br />

Campbell River<br />

ywzhou@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=59990&_<br />

Type=Researchers-Database&_<br />

Title=Zhou-Dr.-Youwen<br />

Neuroendocrine<br />

disorders, diabetes,<br />

dyslipidemia,<br />

obesity<br />

Diabetes<br />

Endocrinology<br />

N/A N/A Orthopedics/ rehab<br />

Brown, Sean Fraser Health N/A N/A Orthopedics


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

215<br />

DISEASE<br />

SPECIALTY<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

MUSCULO-<br />

SKELETAL<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Burnett,<br />

Stephen<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Van Isl<strong>and</strong> Health<br />

Authority<br />

Garbuz, Don Orthopedics Medicine UBC Van Coastal Health<br />

Research Institute<br />

Goetz,<br />

Thomas<br />

Greidanus,<br />

Nelson<br />

Orthopedics Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Orthopedics Medicine UBC Van Coastal Health<br />

Research Institute<br />

Leith, Jordan Orthopedics Medicine UBC Van Coastal Health<br />

Research Institute<br />

McCormack,<br />

Robert<br />

Naude, J. Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

O'Brien, Peter<br />

J.<br />

stephen.burnett@viha.ca N/A Orthopedics<br />

garbuz@shaw.ca http://www.hiphealth.ca/People/<br />

Faculty.htm#g<br />

goetz@vbjc.ca http://www.orthosurgery.ubc.ca/<br />

faculty_bios/goetz.html<br />

Nelson.greidanus@vch.ca http://www.orthosurgery.ubc.ca/<br />

faculty_bios/greidanus.html<br />

jmleith@interchange.ubc.ca http://www.orthosurgery.ubc.ca/<br />

faculty_bios/leith.html<br />

Orthopedics<br />

Orthopedics<br />

Orthopedics<br />

Orthopedics<br />

Fraser Health N/A N/A Orthopedics<br />

N/A N/A Orthopedics<br />

Orthopedics Medicine UBC UBC Campus pjobrien@interchange.ubc.ca http://www.orthosurgery.ubc.ca/<br />

faculty_bios/obrien.html<br />

Pisesky, W. Surgery Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

Reilly,<br />

Christopher<br />

Salvian,<br />

Anthony<br />

Orthopedics Medicine UBC Child & Family<br />

Research Institute<br />

Surgery Medicine UBC Van Coastal Health<br />

Research Institute<br />

Selby, Kathryn Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Smith, Donna Orthopedics Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Orthopedics<br />

N/A N/A Orthopedics<br />

creilly@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=108<br />

anthony.salvian@ubc.ca http://www.surgery.ubc.ca/faculty/<br />

asalvian.html<br />

kselby@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=382<br />

dsmith@vbjc.ca www.orthosurgery.ubc.ca/faculty_<br />

bios/smith.html<br />

Scoliosis<br />

Dystrophy<br />

Orthopedics


216<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

MUSCULO-<br />

SKELETAL<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Younger,<br />

Alastair<br />

Orthopedics Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

NEONATOLOGY Barclay A Van Isl<strong>and</strong> Health<br />

Authority<br />

NEONATOLOGY Lim, Ken Medicine UBC Child & Family<br />

Research Institute<br />

NEONATOLOGY Mayer,<br />

Chantel<br />

NEONATOLOGY Osiovich,<br />

Horacio<br />

NEONATOLOGY Skippen,<br />

Peter<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

NEONATOLOGY Smyth, John Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

NEONATOLOGY Solimano,<br />

Alfonso<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

NEONATOLOGY Tan Dy, C Van Isl<strong>and</strong> Health<br />

Authority<br />

NEONATOLOGY Von<br />

Dadelszen,<br />

Peter<br />

OBSTETRICS &<br />

GYNECOLOGY<br />

Goncalves,<br />

Jose<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Child & Family<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Interior Health<br />

Authority-Penticton<br />

Regional Hospital<br />

asyounger@shaw.ca http://www.specialistclinic.ca/physicians_AlastairYounger.php<br />

N/A N/A<br />

klim@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=78<br />

Orthopedics<br />

Cardiology, pregnancy<br />

N/A N/A Neonatology<br />

hosiovich@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012356<br />

pskippen@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=348<br />

jsmyth@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51146<br />

asolimano@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51147<br />

N/A N/A<br />

pdadelszen@cw.bc.ca; pvd@<br />

cw.bc.ca<br />

N/A N/A<br />

http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=140<br />

Neonatology<br />

Sepsis<br />

Care<br />

Care<br />

Pregnancy, neonatology


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

217<br />

DISEASE<br />

SPECIALTY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Basson,<br />

Rosemary<br />

Brotto, Lori Obstetrics &<br />

Gynecology<br />

Butler, Blair Obstetrics &<br />

Gynecology<br />

Psychiatry Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Women's Health<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Carter, Diana Psychiatry Medicine UBC Child & Family<br />

Research Institute<br />

Cheung,<br />

Anthony P<br />

Obstetrics &<br />

Gynecology<br />

Cundiff, Geoff Obstetrics &<br />

Gynecology<br />

Delisle, Marie-<br />

France<br />

Douglas,<br />

Joanne<br />

Farquharson,<br />

Duncan<br />

Obstetrics &<br />

Gynecology<br />

mdelisle@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=30<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Gagnon, Alain Obstetrics &<br />

Gynecology<br />

Geoffrion,<br />

Roxana<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Women's Health<br />

Research Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

sexmed@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

50943<br />

lori.brotto@vch.ca www.whri.org/projects<strong>and</strong>people/<br />

people/Brotto.htm<br />

Reproduction<br />

Cervical, endometrial,<br />

gynecology<br />

bbutler@cw.bc.ca N/A Pregnancy<br />

diana.carter@ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

50945<br />

apcheung@interchange.ubc.ca;<br />

acheung3@cw.bc.ca<br />

gcundiff@providencehealth.<br />

bc.ca<br />

http://www.obstgyn.ca/About/<br />

dir_profile.htmlID=14<br />

www.whri.org/projects<strong>and</strong>people/<br />

people/CundiffGeoff.htm<br />

jdouglas@cw.bc.ca http://www.whri.org/projects<strong>and</strong>people/people/Douglas.htm<br />

Fraser Health N/A N/A<br />

Gynecology<br />

Reproduction<br />

Gynecology<br />

Pregnancy<br />

Pregnancy<br />

agagnon@cw.bc.ca N/A Pregnancy<br />

rgeoffrion@providencehealth.<br />

bc.ca<br />

www.obstgyn.ca/About/dir_detail.<br />

htmID=469<br />

Gynecology<br />

Havelock, Jon Fraser Health N/A N/A Obstetrics


218<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

OBSTETRICS &<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Liston, Rob Obstetrics &<br />

Gynecology<br />

Magee, Laura<br />

A.<br />

Marquette,<br />

Gerald<br />

Money,<br />

Deborah<br />

Obstetrics &<br />

Gynecology<br />

Obstetrics &<br />

Gynecology<br />

Obstetrics &<br />

Gynecology<br />

Prior , Jerilynn Endocrinology<br />

& Metabolism<br />

Rowe,<br />

Timothy<br />

S<strong>and</strong>ers,<br />

Barry<br />

Obstetrics &<br />

Gynecology<br />

Obstetrics &<br />

Gynecology<br />

Skoll, Am<strong>and</strong>a Obstetrics &<br />

Gynecology<br />

Stephenson,<br />

Mary<br />

Thompson,<br />

David<br />

Obstetrics &<br />

Gynecology<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UBC Child & Family<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Women's Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Child & Family<br />

Research Institute<br />

rliston@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=79<br />

lmagee@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=86<br />

gmarquette@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

001292<br />

Pregnancy<br />

Pregnancy<br />

Pregnancy<br />

HPV, pregnancy<br />

jerilynn.prior@vch.ca www.cemcor.ubc.ca/about/staff#prior Gynecology<br />

trowe@unixg.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=41811&_<br />

Type=Researchers-Database&_<br />

Title=Rowe-Dr.-Timothy-C.<br />

obgroup@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7034<br />

46448<br />

askoll@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/<br />

search_results.asp<br />

mstephen@babies.bsd.uchicago.<br />

edu<br />

dmoney@cw.bc.ca http://www.whri.org/projects<strong>and</strong>people/people/Money.htm<br />

http://www.obstgyn.ca/About/dir_detail.htmID=80<br />

david.thompson@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7949<br />

11633<br />

Menopause<br />

Gynecology<br />

Pregnancy<br />

Pregnancy<br />

Pregnancy


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

219<br />

DISEASE<br />

SPECIALTY<br />

OBSTETRICS /<br />

GYNECOLOGY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Von<br />

Dadelszen,<br />

Peter<br />

OPHTHALMOLOGY Holl<strong>and</strong>,<br />

Simon<br />

Obstetrics &<br />

Gynecology<br />

Pregnancy, neonatology<br />

Ophthalmology<br />

& Visual<br />

Science<br />

Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

OPHTHALMOLOGY Jackson, ML Van Isl<strong>and</strong> Health<br />

Authority<br />

OPHTHALMOLOGY Ma, Patrick E Ophthalmology<br />

& Visual<br />

Science<br />

OPHTHALMOLOGY Maberley,<br />

David<br />

OPHTHALMOLOGY Merkur,<br />

Andrew<br />

OPHTHALMOLOGY Mikelberg,<br />

Frederick<br />

OPHTHALMOLOGY Potter,<br />

Michael<br />

OPHTHALMOLOGY Sullivan,<br />

Kathleen<br />

OTHER Alexiadis,<br />

Alex<strong>and</strong>ros<br />

Ophthalmology<br />

& Visual<br />

Science<br />

david.maberley@vch.ca http://www.cmr.ubc.ca/david_maberley.html<br />

Ophthalmology<br />

& Visual<br />

Science<br />

Ophthalmology<br />

& Visual<br />

Science<br />

fsm@interchange.ubc.ca; frederick.mikelberg@vch.ca<br />

Ophthalmology<br />

& Visual<br />

Science<br />

mpotter@eyecarecentre.org http://www.cmr.ubc.ca/michael_potter.html<br />

Ophthalmology<br />

& Visual<br />

Science<br />

OTHER Hu, Joan Statistics &<br />

Actuarial<br />

Science<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Van Coastal Health<br />

Research Institute<br />

OTHER Kirk, P Van Isl<strong>and</strong> Health<br />

Authority<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

pdadelszen@cw.bc.ca; pvd@<br />

cw.bc.ca<br />

http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=140<br />

simon_holl<strong>and</strong>@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=3408<br />

13891<br />

N/A N/A<br />

patma@interchange.ubc.ca;<br />

eyedoc.retina@shaw.ca<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=5088<br />

33130<br />

amerkur@yahoo.com https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

015262<br />

http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=36610&_<br />

Type=Researchers-Database&_<br />

Title=Mikelberg-Dr.-Frederick-S.<br />

Medicine UBC UBC Campus kathleen_sullivan@telus.net https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51289<br />

Transplant<br />

Diabetes<br />

AMD<br />

AMD<br />

Glaucoma<br />

AMD<br />

Glaucoma<br />

Fraser Health N/A N/A Palliative care<br />

SFU joanh@stat.sfu.ca http://www.stat.sfu.ca/~joanh/ HIV<br />

N/A N/A Palliative care


220<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

OTHER Warburton,<br />

Rebecca N<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Public Administration<br />

OTHER Marra, Carlo Pharmaceutical<br />

<strong>Sciences</strong><br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

UVic rnwarbur@uvic.ca http://publicadmin.uvic.ca/aboutUs/<br />

staffPersonal/warburton.php<br />

UBC Van Coastal Health<br />

Research Institute<br />

OTHER Popkin, JS Van Isl<strong>and</strong> Health<br />

Authority<br />

PULMONARY Ayas, Najib Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

PULMONARY Bai, Tony Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Chilvers, Mark Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

PULMONARY Davidson,<br />

George<br />

PULMONARY Dorscheid,<br />

Delbert<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine -<br />

Critical Care<br />

UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Fera, Tharwat Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Fitzgerald,<br />

Mark<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

PULMONARY Hogg, James iCAPTURE Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Carlo.marra@ubc.ca www.pharmacy.ubc.ca/faculty_staff/<br />

faculty/practice/practice_carlo_marra.<br />

html<br />

N/A N/A<br />

najib.ayas@vch.ca http://ubc-sleepdisorders.vch.ca/ayas.<br />

htm<br />

tony.bai@hli.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_tony_bai.shtml<br />

mchilvers@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

016640<br />

gdavidson@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1731<br />

02098<br />

ddorscheid@hli.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_del_dorscheid.shtml<br />

tfera01@shaw.ca http://www.providenceresearch.ca/<br />

directory/index.aspx<br />

markf@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=40909&_<br />

Type=Researchers-Database&_<br />

Title=FitzGerald-Dr.-J.-Mark<br />

jhogg@mrl.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_jim_hogg.shtml<br />

Arthritis, psoriasis<br />

Apnea<br />

Asthma, bronchiastasis,<br />

COPD, fibrosis<br />

Cystic fibrosis<br />

Cystic fibrosis<br />

COPD, inflammatory,<br />

ARDS<br />

COPD<br />

Asthma, bronchiastasis.<br />

COPD<br />

COPD


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

221<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

PULMONARY Innis, Sheila Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

PULMONARY Khalil,<br />

Nasreen<br />

PULMONARY Knight, Darryl Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Lam, Stephen Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

PULMONARY Lawson,<br />

Edward<br />

PULMONARY Lawson,<br />

Lindsay<br />

Respiratory<br />

Medicine<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Levy, Robert Medicine Medicine UBC Providence Health<br />

Care Research Institute/<br />

Van Coastal<br />

Health Research<br />

Institute<br />

PULMONARY Lillquist,<br />

Yol<strong>and</strong>a<br />

PULMONARY Man, Paul Respiratory<br />

Medicine<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

sinnis@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=61<br />

nkhalil@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=74097&_<br />

Type=Researchers-Database&_<br />

Title=Khalil-Dr.-Nasreen<br />

dknight@mrl.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_darryl_knight.shtml<br />

slam2@bccancer.bc.ca www.bccancerfoundation.com/<br />

cms/page1396.cfm; http://www.<br />

researchers.vchri.ca/s/Researchers.aspReportID=69170&_<br />

Type=Researchers-Database&_<br />

Title=Lam-Dr.-Stephen-C.<br />

Development, cystic<br />

fibrosis<br />

Fibrosis<br />

Asthma<br />

Asthma<br />

Fraser Health N/A N/A Asthma<br />

llawson@providencehealth.bc.ca www.pacificlung.com/who_we_are.<br />

php<br />

rlevy@providencehealth.bc.ca http://www.icapture.ubc.ca/who/<br />

who_robert_Levy.shtml<br />

ylillquist@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

53873<br />

pman@providencehealth.bc.ca www.pacificlung.com/who_we_are.<br />

php<br />

Asthma, complications<br />

of HIV<br />

COPD, fibrosis,<br />

hypertension<br />

Cystic fibrosis<br />

COPD


222<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

PULMONARY McCauley, G. Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

PULMONARY Nakielna,<br />

Barbara<br />

Respiratory<br />

Medicine<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Ostrow, David Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

PULMONARY Paré, Peter Medicine &<br />

Pathology<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Road, Jeremy Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

PULMONARY Rolf, J.Douglas Medicine Medicine UBC Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

PULMONARY Ronco, Juan Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

PULMONARY Schellenberg,<br />

Robert<br />

iCAPTURE Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Sin, Donald Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

N/A N/A COPD<br />

bnakielna@providencehealth.<br />

bc.ca<br />

ostrow@telus.net; david.<br />

ostrow@vch.ca<br />

www.pacificlung.com/who_we_are.<br />

php<br />

http://www.vch.ca/about_us/<br />

leadership/senior_executive_team/<br />

dr._david_n._ostrow<br />

ppare@mrl.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_peter_pare.shtml<br />

jroad@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=43383&_<br />

Type=Researchers-Database&_<br />

Title=Road-Dr.-Jeremy-D.<br />

Cystic fibrosis<br />

Hypertension<br />

COPD<br />

COPD<br />

douglass.rolf@interiorhealth.ca www.directory.ubc.ca/index.cfm Influenza<br />

jronco@vanhosp.bc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=65892&_<br />

Type=Researchers-Database&_<br />

Title=Ronco-Dr.-Juan-J.<br />

bschellenberg@mrl.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_bob_schellenberg.shtml<br />

dsin@mrl.ubc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_don_sin.shtml<br />

ARDS<br />

Asthma<br />

COPD


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

223<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

PULMONARY Singh, Avash Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

PULMONARY Stenstrom,<br />

Robert<br />

Family<br />

Practice<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

PULMONARY Swiston, John Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

PULMONARY Takaro,<br />

Timothy<br />

PULMONARY Tan-Hogg,<br />

Wan<br />

PULMONARY van Eeden,<br />

Stephan F.<br />

PULMONARY Wensley,<br />

David<br />

PULMONARY Wilcox, Pearce<br />

G.<br />

SURGERY Bond, R.<br />

James<br />

SURGERY Cunningham,<br />

C.<br />

Health <strong>Sciences</strong><br />

Medicine Medicine –<br />

Respiratory<br />

Medicine<br />

Respiratory<br />

Medicine<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

ajsingh@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=384<br />

robstenstrom@shaw.ca http://www.sphemerg.ca/research/<br />

stenstrom<br />

swiston@interchange.ubc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

014581<br />

SFU ttakaro@sfu.ca www.fhs.sfu.ca/portal_memberdata/<br />

timt<br />

UBC Providence Health<br />

Care Research<br />

Institute<br />

Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

wtan@mrl.ubc.ca www.pacificlung.com/who_we_are.<br />

php<br />

svaneeden@mrl.ubc.ca www.pacificlung.com/who_we_are.<br />

php<br />

dwensley@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8530<br />

18927<br />

pwilcox@providencehealth.bc.ca http://www.icapture.ubc.ca/who/<br />

who_bios_pearce_wilcox.shtml<br />

RSV<br />

Asthma<br />

Hypertension<br />

Allergies<br />

Asthma, COPD<br />

Chronic bronchitis,<br />

emphysema<br />

ARDS<br />

Cystic fibrosis,<br />

asthma, COPD<br />

Fraser Health N/A N/A Thoracic surgery,<br />

cancer<br />

Interior Health<br />

Authority-Vernon<br />

Jubilee Hospital<br />

SURGERY Du Plessis, J. Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

SURGERY Hayashi, A Van Isl<strong>and</strong> Health<br />

Authority<br />

N/A N/A Orthopedics<br />

N/A N/A Orthopedics<br />

N/A N/A Pediatrics


224<br />

BRITISH COLUMBIA<br />

6.2 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Disease Area Specialty (cont’d)<br />

DISEASE<br />

SPECIALTY<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

SURGERY Javer, Amin Surgery Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

SURGERY Lerch, L Van Isl<strong>and</strong> Health<br />

Authority<br />

SURGERY Orrom,<br />

William<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

Van Isl<strong>and</strong> Health<br />

Authority<br />

SURGERY Piper, HG UBC Van Isl<strong>and</strong> Health<br />

Authority<br />

SURGERY Pisesky, W. Surgery Interior Health<br />

Authority-Kelowna<br />

General Hospital<br />

SURGERY Skarsgard,<br />

Eric<br />

Surgery UBC Child & Family<br />

Research Institute<br />

SURGERY Tang, Bao Van Isl<strong>and</strong> Health<br />

Authority<br />

TRANSPLANT Davis, Jeffrey Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

TRANSPLANT Hurley, R.<br />

Morrison<br />

TRANSPLANT Ignaszewski,<br />

Andrew<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

TRANSPLANT Keown, Paul Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

sinussurgeon@drjaver.com http://www.surgery.ubc.ca/faculty/<br />

ajaver.html<br />

Polyps<br />

N/A N/A Surgery<br />

Canada. truenorth222@yahoo.<br />

com<br />

N/A Surgery<br />

hgpiper@interchange.ubc.ca N/A Surgery<br />

N/A N/A Orthopedics<br />

eskarsgard@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.<br />

aspID=123<br />

bao.tang@shaw.ca N/A Surgery<br />

mhurley@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

53869<br />

jdavis@cw.bc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=269<br />

aignaszewski@providencehealth.bc.ca<br />

https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=8997<br />

51017<br />

keown@interchange.ubc.ca http://www.researchers.vchri.ca/s/<br />

Researchers.aspReportID=66522&_<br />

Type=Researchers-Database&_<br />

Title=Keown-Dr.-Paul-A.<br />

Fetal diagnosis/<br />

therapy, neonatology<br />

GVHD<br />

GVHD<br />

Congestive heart<br />

failure, coronary<br />

disease<br />

Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

225<br />

DISEASE<br />

SPECIALTY<br />

TRANSPLANT Matsuda-<br />

Abedini, Mina<br />

TRANSPLANT Shapiro, R.<br />

Jean<br />

TRANSPLANT Straatman,<br />

Lynn<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED<br />

UNI-<br />

VERSITY<br />

Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

Medicine Medicine UBC Van Coastal Health<br />

Research Institute<br />

Pediatrics Medicine UBC Providence Health<br />

Care Research<br />

Institute<br />

TRANSPLANT Schultz, Kirk Pediatrics Medicine UBC Child & Family<br />

Research Institute<br />

INSTITUTION EMAIL URL SPECIFIC DISEASE/<br />

CONDITION<br />

mmatsuda@cw.bc.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=1000<br />

012350<br />

jean.shapiro@vch.ca https://www.directory.ubc.ca/index.<br />

cfmpage=personDetail&row=7252<br />

75114<br />

lstraatman@providencehealth.<br />

bc.ca<br />

http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=296<br />

kschultz@interchange.ubc.ca http://www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=119<br />

Renal<br />

Melanoma<br />

Leukemia, GVHD


226<br />

BRITISH COLUMBIA<br />

6.3 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Other Areas of Specialty<br />

Epidemiology, Health Economics, Health Outcomes<br />

Note that a number of investigators are listed multiple times due to their clinical trials activities in more than one area.<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Epidemiology<br />

Chanoine, Jean-<br />

Pierre<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute jchanoine@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=20<br />

Chiu, Anthony Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Chockalingam,<br />

Arum<br />

Choi, Peter Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

antchiu@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=133<br />

287841<br />

Health <strong>Sciences</strong> SFU achockal@sfu.ca www.fhs.sfu.ca/portal_memberdata/arun<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Clarke, Lorne Medical Genetics Medicine UBC Van Coastal Health Research<br />

Institute<br />

Conway, Brian Anesthesia Medicine UBC Van Coastal Health Research<br />

Institute/ Providence Health Care<br />

Research Institute<br />

Cooper, S. Interior Health Authority-Penticton<br />

Regional Hospital<br />

PeterT.Choi@vch.ca http://www.apt.ubc.ca/<br />

anesthesiology/Vancouver_General_Hospital/<br />

Department_Members/<br />

Dr_Peter_Choi.htm<br />

lclarke@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=24<br />

bconway@interchange.<br />

ubc.ca<br />

http://www.mhanet.ca/<br />

search/node/35<br />

Metabolic/ endocrine Growth<br />

Genitourinary Renal<br />

CV / cardiology Hypertension<br />

Anesthesiology, CV /<br />

cardiology<br />

Metabolic/ endocrine Genetic disease<br />

ID/ infection Hepatitis, HIV<br />

N/A N/A Genitourinary Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

227<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Dix, David Pediatrics Medicine UBC Child & Family Research Institute ddix@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=260<br />

Duncan, John A. Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Dunne, James<br />

V.<br />

medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Dvorak, Marcel Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

Fischer,<br />

Benedikt<br />

Fung, Anthony<br />

Y-F.<br />

john.duncan@shaw.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=41711&_<br />

Type=Researchers-Data-<br />

base&_Title=Duncan-Dr.-<br />

John-A<br />

drjdunne@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=204<br />

769036<br />

vanspine@interchange.<br />

ubc.ca<br />

http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=45184&_<br />

Type=Researchers-<br />

Database&_Title=Dvorak-<br />

Dr.-Marcel-F.<br />

Health <strong>Sciences</strong> SFU bfa11@sfu.ca www.fhs.sfu.ca/portal_<br />

memberdata/bfischer<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Gill, John Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Hayden,<br />

Michael<br />

funga@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=257<br />

342302<br />

jgill@providencehealth.<br />

bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

006603<br />

CMMT Medicine UBC Child & Family Research Institute mrh@cmmt.ubc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=54<br />

Cancer Complications<br />

Genitourinary, metabolic/<br />

endocrine<br />

CV / cardiology,<br />

autoimmune<br />

Renal<br />

CNS SCI<br />

ID/ infection Infection<br />

Hypertension, GVHD<br />

CV / cardiology Acute coronary<br />

syndrome<br />

Genitourinary Renal<br />

CNS Huntingdon’s


228<br />

BRITISH COLUMBIA<br />

6.3 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Other Areas of Specialty (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Hogg, Robert Population &<br />

Public Health/<br />

Health <strong>Sciences</strong><br />

Hu, Joan Statistics & Actuarial<br />

Science<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC/ SFU Providence Health Care Research<br />

Institute<br />

Jue, John C. Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Karim,<br />

Mohamud<br />

Kiess, Marla Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Kwon, Janice Obstetrics &<br />

Gynecology<br />

Lear, Scott Biomedical<br />

Physiology<br />

robert_hogg@sfu.ca www.fhs.sfu.ca/portal_<br />

memberdata/rhogg<br />

SFU joanh@stat.sfu.ca http://www.stat.sfu.<br />

ca/~joanh/<br />

jjue@unixg.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=383<br />

395162<br />

ID/ infection HIV/AIDS<br />

ID/ infection, other HIV<br />

CV / cardiology Coronary disease<br />

Fraser Health N/A N/A Genitourinary Renal<br />

Medicine UBC B.C. Cancer Agency / Van Coastal<br />

Health Research Institute<br />

SFU Providence Health Care Research<br />

Institute<br />

mkiess@providencehealth.<br />

bc.ca<br />

http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

N/A www.powerstudy.ca/<br />

profile/janice-kwon<br />

salear@sfu.ca; slear@<br />

providencehealth.bc.ca<br />

www2.fas.sfu.ca/kin/Faculty.html;<br />

http://www.<br />

cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.aspID=281<br />

Leavitt, Blair CMMT Medicine UBC Child & Family Research Institute bleavitt@cmmt.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=40908&_<br />

Type=Researchers-<br />

Database&_Title=Leavitt-<br />

Dr.-Blair-R.<br />

Levin, Adeera Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Man, Paul Respiratory<br />

Medicine<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

alevin@providencehealth.<br />

bc.ca<br />

pman@providencehealth.<br />

bc.ca<br />

http://www.krescent.ca/<br />

Page.aspxpid=755<br />

www.pacificlung.com/<br />

who_we_are.php<br />

CV / cardiology Hypertension<br />

Cancer Cervical, endometrial,<br />

gynecology<br />

Metabolic/ endocrine,<br />

CV/ cardiology<br />

Metabolic/ endocrine,<br />

CV/ cardiology<br />

Obesity, coronary<br />

disease<br />

Genetic disease,<br />

coronary disease<br />

Genitourinary Dialysis, renal<br />

Pulmonary COPD


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

229<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Montaner, Julio Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Ong, May Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Orenstein Lyall,<br />

Teddi Lynn<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Phillips, Peter Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Prior , Jerilynn Endocrinology &<br />

Metabolism<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Ronco, Juan Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Sadovnick, A.<br />

Dessa<br />

Sanatani,<br />

Shubhayan<br />

Shereck, Evan<br />

B.<br />

Medical Genetics Medicine UBC Van Coastal Health Research<br />

Institute<br />

jmontaner@cfenet.ubc.ca http://www.cmeonhiv.<br />

com/pub/dr..julio.montaner.php<br />

dr.ong@telus.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=59768<br />

5024aspx<br />

ID/ infection HIV<br />

CNS Pain<br />

Orenstein@telus.net N/A CV / cardiology Acute coronary<br />

syndrome<br />

pphillips@cfenet.ubc.ca http://www.ID.med.ubc.<br />

ca/Faculty/Peter_Phillips.<br />

htm<br />

jerilynn.prior@vch.ca www.cemcor.ubc.ca/<br />

about/staff#prior<br />

jronco@vanhosp.bc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=65892&_<br />

Type=Researchers-<br />

Database&_Title=Ronco-<br />

Dr.-Juan-J.<br />

sadovnik@infinet.net https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=699<br />

295927<br />

Pediatrics Medicine UBC Child & Family Research Institute ssanatani@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=114<br />

Pediatrics Medicine UBC Child & Family Research Institute eshereck@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=295<br />

ID/ infection HIV<br />

Obstetrics / gynecology<br />

Critical care, pulmonary<br />

Gynecology<br />

ARDS<br />

CNS Brain/CNS<br />

CV / cardiology Coronary disease<br />

Cancer/ hematology


230<br />

BRITISH COLUMBIA<br />

6.3 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Other Areas of Specialty (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Sin, Donald Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

dsin@mrl.ubc.ca http://www.icapture.ubc.<br />

ca/who/who_bios_don_<br />

sin.shtml<br />

Steinbok, Paul Surgery Medicine UBC Child & Family Research Institute psteinbok@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=127<br />

Stockler, Sylvia Pediatrics Medicine UBC UBC Campus sstockler@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=255<br />

Tan-Hogg, Wan Medicine Medicine<br />

– Respiratory<br />

Medicine<br />

UBC Providence Health Care Research<br />

Institute<br />

Tsui, Joseph Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

wtan@mrl.ubc.ca www.pacificlung.com/<br />

who_we_are.php<br />

jtsui@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

005466<br />

Tucker, Lori Pediatrics Medicine UBC Child & Family Research Institute ltucker@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=134<br />

Von Dadelszen,<br />

Peter<br />

Vorobeychik,<br />

Galina<br />

Obstetrics &<br />

Gynecology<br />

Medicine UBC Child & Family Research Institute pdadelszen@cw.bc.ca; pvd@<br />

cw.bc.ca<br />

Medicine Medicine UBC Fraser Health galina.vorobeychik@fraserhealth.ca<br />

http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=140<br />

Pulmonary COPD<br />

CNS Brain injury<br />

Metabolic/ endocrine Genetic disease<br />

Pulmonary Asthma, COPD<br />

CNS Parkinson’s<br />

Autoimmune,<br />

genitourinary<br />

Obstetrics / gynecology,<br />

neonatology<br />

N/A CNS MS<br />

Rheumatology,<br />

renal<br />

Pregnancy, neonatology


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

231<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Wai, Elaine Medicine Medicine UBC B.C. Cancer Agency N/A http://www.surgery.ubc.<br />

ca/faculty/ewai.html<br />

Cancer Breast, lung<br />

Wambera, Kati Pediatrics Medicine UBC Child & Family Research Institute N/A N/A CNS Brain/CNS<br />

Webb, John Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

webb@providencehealth.<br />

bc.ca<br />

http://www.bccrc.ca/drc/<br />

people_jwebb.html<br />

Wensley, David Pediatrics Medicine UBC Child & Family Research Institute dwensley@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=853<br />

018927<br />

White, Colin Pediatrics Medicine UBC Child & Family Research Institute cwhite@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=247<br />

Wu, John K. Pediatrics Medicine UBC Child & Family Research Institute jwu@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=249<br />

Health Economics<br />

Anis, Aslam Population &<br />

Public Health<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

aslam.anis@ubc.ca http://www.mhanet.ca/<br />

search/node/15<br />

Bardal, Stan K Medical <strong>Sciences</strong> UVic bardals@uvic.ca http://www.zoominfo.com/people/Bardal_<br />

Stan_1207852047.aspx<br />

Farrell, Kevin Pediatrics Medicine UBC Child & Family Research Institute kfarrell@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=38<br />

CV / cardiology Coronary bypass,<br />

myocardial infarction,<br />

cardiac surgery,<br />

angioplasty/<br />

stent<br />

Pulmonary, critical<br />

care<br />

ARDS<br />

Genitourinary Renal<br />

Hematology Genetic disease, infection,<br />

thrombosis/<br />

coagulation<br />

CV / cardiology,<br />

metabolic/ endocrine<br />

CV / cardiology<br />

Hypertension,<br />

obesity<br />

CNS Epilepsy/ seizures


232<br />

BRITISH COLUMBIA<br />

6.3 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Other Areas of Specialty (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Greidanus,<br />

Nelson<br />

Hogg, Robert Population &<br />

Public Health/<br />

Health <strong>Sciences</strong><br />

Kwon, Janice Obstetrics &<br />

Gynecology<br />

Orthopedics Medicine UBC Van Coastal Health Research<br />

Institute<br />

Marra, Carlo Pharmaceutical<br />

<strong>Sciences</strong><br />

McElhaney,<br />

Janet<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC/ SFU Providence Health Care Research<br />

Institute<br />

Medicine UBC B.C. Cancer Agency / Van Coastal<br />

Health Research Institute<br />

UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Nelson.greidanus@vch.ca http://www.orthosurgery.<br />

ubc.ca/faculty_bios/<br />

greidanus.html<br />

robert_hogg@sfu.ca www.fhs.sfu.ca/portal_<br />

memberdata/rhogg<br />

N/A www.powerstudy.ca/<br />

profile/janice-kwon<br />

Carlo.marra@ubc.ca www.pharmacy.ubc.ca/<br />

faculty_staff/faculty/<br />

practice/practice_carlo_<br />

marra.html<br />

janet.mcelhaney@ubc.ca http://www.ID.med.ubc.<br />

ca/Faculty/Associate_<br />

Members/Janet_McElhaney.htm<br />

Musculo-skeletal Orthopedics<br />

ID/ infection HIV/AIDS<br />

Cancer Cervical, endometrial,<br />

gynecology<br />

Autoimmune, dermatology,<br />

other<br />

Arthritis, psoriasis<br />

ID/ infection Herpes, respiratory<br />

Pluta, Henryk Fraser Health N/A N/A Gastro-intestinal Gastro-enterology<br />

Prest, Marcia Fraser Health N/A N/A Gastro-intestinal Gastro-enterology<br />

Rivers, Jason Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Schreiber,<br />

Richard<br />

N/A http://www.dermatology.<br />

ca/find_derm/profiles/<br />

jason_k_rivers.html<br />

Pediatrics Medicine UBC Child & Family Research Institute rschreiber@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=118<br />

Teal, Philip Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

teal@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=38022&_<br />

Type=Researchers-<br />

Database&_Title=Teal-<br />

Dr.-Philip-A.<br />

Dermatology Inflammatory,<br />

psoriasis<br />

Gastro-intestinal Liver disease<br />

CNS Stroke


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

233<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Vorobeychik,<br />

Galina<br />

Warburton,<br />

Rebecca N<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine Medicine UBC Fraser Health galina.vorobeychik@fraserhealth.ca<br />

Public Administration<br />

Health Outcome<br />

Ashton, Thomas Medicine Medicine UBC Interior Health Authority-Penticton<br />

Regional Hospital<br />

Aymong, Eve Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Bernstein,<br />

Victoria<br />

Buller,<br />

Christopher<br />

Christenson,<br />

Jim<br />

UVic rnwarbur@uvic.ca http://publicadmin.uvic.<br />

ca/aboutUs/staffPersonal/<br />

warburton.php<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Cardiology Medicine UBC Van Coastal Health Research<br />

Institute<br />

Surgery Medicine UBC Providence Health Care Research<br />

Institute<br />

Clarke, Lorne Medical Genetics Medicine UBC Van Coastal Health Research<br />

Institute<br />

N/A www.directory.ubc.ca/<br />

index.cfm<br />

N/A CNS MS<br />

eaymong@providencehealth.bc.ca<br />

http://www.biomedexperts.com/Profile.<br />

bme/63107/Eve_D_Aymong<br />

dr.bernstein@telus.net http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=41888&_<br />

Type=Researchers-Data-<br />

base&_Title=Bernstein-<br />

Dr.-Victoria<br />

cehbuller@shaw.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=41916&_<br />

Type=Researchers-<br />

Database&_Title=Buller-<br />

Dr.-Christopher-E.<br />

Other<br />

CV / cardiology Acute coronary<br />

syndrome<br />

CV / cardiology Acute coronary<br />

syndrome<br />

CV / cardiology Acute coronary<br />

syndrome<br />

CV / cardiology Acute coronary<br />

syndrome<br />

jimchris@interchange.ubc.ca N/A CV / cardiology Myocardial infarction<br />

lclarke@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=24<br />

Metabolic/ endocrine Genetic disease


234<br />

BRITISH COLUMBIA<br />

6.3 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Other Areas of Specialty (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Cochrane, Doug Surgery Medicine UBC Child & Family Research Institute dcochrane@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=26<br />

Conway, Brian Anesthesia Medicine UBC Van Coastal Health Research<br />

Institute/ Providence Health Care<br />

Research Institute<br />

Davison, Joyce Nursing UBC Van Coastal Health Research<br />

Institute<br />

Dawson, Keith Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Devonshire,<br />

Virginia<br />

Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

bconway@interchange.<br />

ubc.ca<br />

http://www.mhanet.ca/<br />

search/node/35<br />

joyce.davison@vch.ca www.prostatecentre.<br />

com/aboutus/aboutus.<br />

phppageID=158<br />

kdaw@interchange.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=177<br />

713788<br />

vdev@shaw.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751733<br />

CNS<br />

ID/ infection Hepatitis, HIV<br />

Genitourinary, cancer Prostate cancer<br />

CV / cardiology Coronary disease<br />

CNS MS<br />

Dewet, Joseph Family Practice Medicine UBC UBC Campus N/A N/A ID/ infection HIV<br />

Ervin, Frank General Internal<br />

Medicine<br />

Medicine UBC Fraser Health flervin@telus.net N/A CV / cardiology Acute coronary<br />

syndrome<br />

Gleave, Martin Surgery Medicine UBC Van Coastal Health Research<br />

Institute<br />

gleave@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=63578&_<br />

Type=Researchers-<br />

Database&_Title=Gleave-<br />

Dr.-Martin-E.<br />

Genitourinary, cancer Prostate<br />

Gordon, Wendy Fraser Health N/A N/A CV / cardiology<br />

N/A N/A Autoimmune Arthritis<br />

Gross,<br />

Katherine<br />

Interior Health Authority-Penticton<br />

Regional Hospital<br />

Halperin, Ross B.C. Cancer Agency rhalperin@bcancer.bc.ca N/A Cancer Prostate


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

235<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Hayden, Robert Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

Hilton, Donald Van Isl<strong>and</strong> Health Authority -<br />

Cowichan District Hospital<br />

Hogg, Robert Population &<br />

Public Health/<br />

Health <strong>Sciences</strong><br />

Medicine UBC/ SFU Providence Health Care Research<br />

Institute<br />

Imrie, John Van Coastal Health-Lion's Gate<br />

Hospital<br />

Jue, John C. Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Kerr, Charles Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Kornder, Jan Fraser Health-Surrey Memorial<br />

Hospital<br />

Lai, Kevin Van Isl<strong>and</strong> Health Authority-<br />

Nanaimo Regional General<br />

Hospital<br />

N/A N/A ID/ infection HIV/AIDS<br />

robert_hogg@sfu.ca www.fhs.sfu.ca/portal_<br />

memberdata/rhogg<br />

CV / cardiology Acute coronary<br />

syndrome<br />

N/A N/A CV / cardiology Coronary disease<br />

jjue@unixg.ubc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=383<br />

395162<br />

ckerr@providencehealth.<br />

bc.ca<br />

Jan.Kornder@fraserhealth.<br />

ca<br />

http://www.providenceresearch.ca/directory/<br />

ResearcherDetail.aspx<br />

CV / cardiology Coronary disease<br />

CV / cardiology Acute coronary<br />

syndrome<br />

N/A CV / cardiology Acute coronary<br />

syndrome<br />

N/A N/A Surgery Surgery<br />

Lerch, L Van Isl<strong>and</strong> Health Authority N/A N/A Genitourinary Dialysis, renal<br />

Pregnancy<br />

Levin, Adeera Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Liston, Rob Obstetrics &<br />

Gynecology<br />

Magee, Laura A. Obstetrics &<br />

Gynecology<br />

alevin@providencehealth.<br />

bc.ca<br />

http://www.krescent.ca/<br />

Page.aspxpid=755<br />

UBC Child & Family Research Institute rliston@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=79<br />

Medicine UBC Child & Family Research Institute lmagee@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=86<br />

Obstetrics & gynecology<br />

Obstetrics / gynecology<br />

Obstetrics / gynecology<br />

Pregnancy<br />

Pregnancy


236<br />

BRITISH COLUMBIA<br />

6.3 <strong>Clinical</strong> <strong>Trials</strong> Researchers Listed According to Other Areas of Specialty (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Marra, Carlo Pharmaceutical<br />

<strong>Sciences</strong><br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

UBC Van Coastal Health Research<br />

Institute<br />

Carlo.marra@ubc.ca www.pharmacy.ubc.ca/<br />

faculty_staff/faculty/<br />

practice/practice_carlo_<br />

marra.html<br />

Marsden, Julian Family Practice Medicine UBC UBC Campus N/A http://www.bcpsqc.ca/<br />

celebrating-achievements-in-bc/BCPSQC_Celebrating_Achievements_<br />

Marsden.htm<br />

McDermid,<br />

Kevin<br />

Fraser Health-Langley Memorial<br />

Hospital<br />

Montaner, Julio Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Orrom, William Van Isl<strong>and</strong> Health Authority Canada. truenorth222@<br />

yahoo.com<br />

Polasek, Petr Interior Health Authority-Kelowna<br />

General Hospital<br />

Potter, Michael Ophthalmology<br />

& Visual Science<br />

Priestman, B.<br />

Anne<br />

Ramanathan,<br />

Krishnan<br />

Medicine UBC Van Coastal Health Research<br />

Institute<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

Ricci, Donald Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Autoimmune, dermatology,<br />

other<br />

Arthritis, psoriasis<br />

CV / cardiology Congestive heart<br />

failure<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

jmontaner@cfenet.ubc.ca http://www.cmeonhiv.<br />

com/pub/dr..julio.montaner.php<br />

ID/ infection HIV<br />

N/A Surgery Surgery<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

mpotter@eyecarecentre.org http://www.cmr.ubc.ca/<br />

michael_potter.html<br />

Ophthalmology AMD<br />

Fraser Health N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

kramanathan@providencehealth.bc.ca<br />

https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

011039<br />

ricci@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=66053&_<br />

Type=Researchers-<br />

Database&_Title=Ricci-<br />

Dr.-Donald-R.<br />

CV / cardiology Acute coronary<br />

syndrome<br />

CV / cardiology Acute coronary<br />

syndrome


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

237<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Ronco, Juan Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

Son, Wai Kon Fraser Health-Chilliwack General<br />

Hospital<br />

Thornton,<br />

Allen E<br />

Vorobeychik,<br />

Galina<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

jronco@vanhosp.bc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=65892&_<br />

Type=Researchers-<br />

Database&_Title=Ronco-<br />

Dr.-Juan-J.<br />

Critical care, pulmonary<br />

ARDS<br />

N/A N/A CV / cardiology Acute coronary<br />

syndrome<br />

Psychology SFU aethornt@sfu.ca http://www.sfu.ca/psyc/<br />

faculty/thorntona/<br />

Medicine Medicine UBC Fraser Health galina.vorobeychik@fraserhealth.ca<br />

Weiss, Margaret Psychiatry Medicine UBC Child & Family Research Institute margaret.weiss@me.com http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=145<br />

Yeung-Lai-Wah,<br />

John<br />

Cardiology Medicine UBC Providence Health Care Research<br />

Institute<br />

jayeung@axion.net http://www.providenceresearch.ca/directory/<br />

index.aspx<br />

CNS Schizophrenia,<br />

cognitive<br />

N/A CNS MS<br />

CNS Mental health<br />

CV / cardiology Coronary disease


238<br />

BRITISH COLUMBIA<br />

Pediatrics<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Alimenti,<br />

Ariane<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute aalimenti@cw.bc.ca N/A ID/ infection HIV<br />

Amed, Shazhan Pediatrics Medicine UBC Child & Family Research Institute samed@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=305<br />

Ansermino,<br />

Mark<br />

Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

UBC Child & Family Research Institute mansermino@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.aspID=3<br />

Metabolic/ endocrine Diabetes<br />

Anesthesiology Pediatrics<br />

Barclay A Van Isl<strong>and</strong> Health Authority N/A N/A Neonatology<br />

Bennett, Mary Pediatrics Medicine UBC Child & Family Research Institute mbennett@cw.bc.ca https://www.directory. Metabolic/ endocrine Endocrinology<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

751067<br />

Bjornson, Bruce Pediatrics Medicine UBC Child & Family Research Institute bbjornson@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=387<br />

CNS Stroke, epilepsy<br />

ID/ infection Respiratory<br />

Brunstein, John Biochemistry &<br />

Molec Biology<br />

Butler, Blair Obstetrics &<br />

Gynecology<br />

Medicine UBC Child & Family Research Institute jbrunstein@cw.bc.ca http://www.pathology.<br />

ubc.ca/NewPathology/<br />

<strong>Clinical</strong>AssistantProfessor/<br />

John_Brunstein.html<br />

Medicine UBC Child & Family Research Institute bbutler@cw.bc.ca N/A Obstetrics / gynecology<br />

Cabral, David Pediatrics Medicine UBC Child & Family Research Institute dcabral@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=289<br />

Pregnancy<br />

Autoimmune Rheumatology,<br />

osteoporosis


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

239<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Chanoine, Jean-<br />

Pierre<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Pediatrics Medicine UBC Child & Family Research Institute jchanoine@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=20<br />

Chilvers, Mark Pediatrics Medicine UBC Child & Family Research Institute mchilvers@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=1000<br />

016640<br />

Cochrane, Doug Surgery Medicine UBC Child & Family Research Institute dcochrane@cw.bc.ca www.cfri.ca/our_research/researchers/<br />

search_researchers/<br />

researcher_detail.<br />

aspID=26<br />

Cogswell,<br />

Arthur<br />

Pediatrics Medicine UBC Child & Family Research Institute acogswell@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=899<br />

753861<br />

Connolly, Mary Pediatrics Medicine UBC Child & Family Research Institute mconnolly@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=379<br />

Davidson,<br />

George<br />

Pediatrics Medicine UBC Child & Family Research Institute gdavidson@cw.bc.ca https://www.directory.<br />

ubc.ca/index.cfmpage=<br />

personDetail&row=173<br />

102098<br />

Davis, Jeffrey Pediatrics Medicine UBC Child & Family Research Institute jdavis@cw.bc.ca http://www.cfri.ca/<br />

our_research/researchers/search_researchers/<br />

researcher_detail.<br />

aspID=269<br />

Metabolic/ endocrine Growth<br />

Pulmonary Cystic fibrosis<br />

CNS<br />

CV / cardiology Cardiovascular<br />

disease<br />

CNS Epilepsy/ seizures<br />

Pulmonary Cystic fibrosis<br />

Cancer, transplant GVHD


240<br />

BRITISH COLUMBIA<br />

Pediatrics (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Dix, David Pediatrics Medicine UBC Child & Family Research Institute ddix@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=260<br />

Dobson, Simon Pediatrics Medicine UBC Child & Family Research Institute sdobson@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=899751085<br />

Farrell, Kevin Pediatrics Medicine UBC Child & Family Research Institute kfarrell@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=38<br />

Fitzgerald, Mark Medicine Medicine UBC Van Coastal Health Research<br />

Institute<br />

markf@interchange.ubc.ca http://www.researchers.<br />

vchri.ca/s/Researchers.<br />

aspReportID=40909&_<br />

Type=Researchers-Data-<br />

base&_Title=FitzGerald-Dr.-<br />

J.-Mark<br />

Forbes, John Pediatrics Medicine UBC Child & Family Research Institute jforbes@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=41<br />

Fryer,<br />

Christopher<br />

Gagnon, Alain Obstetrics<br />

& Gynecology<br />

Pediatrics Medicine UBC Child & Family Research Institute cfryer@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=262<br />

Medicine UBC Women's Health Research<br />

Institute<br />

Cancer Complications<br />

ID/ infection Hepatitis, HPV, HSV,<br />

meningitis<br />

CNS Epilepsy/ seizures<br />

Pulmonary Asthma, bronchiastasis.<br />

COPD<br />

ID/ infection HIV<br />

Cancer Brain/CNS<br />

agagnon@cw.bc.ca N/A Obstetrics/ gynecology<br />

Goldman, Ran Pediatrics UBC Child & Family Research Institute rgoldman@cw.bc.ca www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.<br />

aspID=273<br />

Gross, K. Interior Health Authority-Penticton<br />

Regional Hospital<br />

Pregnancy<br />

Emergency medicine Pediatrics<br />

N/A N/A Autoimmune Arthritis


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

241<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Hall, Wendy Nursing Applied<br />

Science<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

UBC UBC Campus wendy.hall@nursing.ubc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=373<br />

CNS Cognitive<br />

Hayashi, A Van Isl<strong>and</strong> Health Authority N/A N/A Surgery Pediatrics<br />

Autoimmune Arthritis<br />

Houghton,<br />

Kristin<br />

Pediatrics Medicine UBC Child & Family Research Institute khoughton@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=286<br />

Hukin, Juliette Pediatrics Medicine UBC Child & Family Research Institute jhukin@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=58<br />

Human, Derek Pediatrics Medicine UBC Child & Family Research Institute dhuman@cw.bc.ca http://www.bcchildrens.ca/<br />

Services/ChildrensHeartCentre/Healthcareteam/Leadershipteam.htm#human<br />

Hurley, R.<br />

Morrison<br />

Pediatrics Medicine UBC Child & Family Research Institute mhurley@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=899753869<br />

Innis, Sheila Pediatrics Medicine UBC Child & Family Research Institute sinnis@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=61<br />

Jacobson, Kevan Pediatrics Medicine UBC Child & Family Research Institute kjacobson@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=62<br />

Jan, James Pediatrics Medicine UBC Child & Family Research Institute jjan@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/search_results.<br />

asp<br />

Kerns, Kimberly<br />

A<br />

Psychology<br />

UVic kkerns@uvic.ca http://web.uvic.ca/psyc/<br />

kerns.html<br />

Cancer Brain/CNS<br />

CV / cardiology Coronary disease<br />

Transplant GVHD<br />

CNS, pulmonary Development, cystic<br />

fibrosis<br />

Gastro-intestinal Crohn’s<br />

CNS FASD<br />

CNS FASD


242<br />

BRITISH COLUMBIA<br />

Pediatrics (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Lauder, Gillian Anesthesiology/<br />

Pharmacology/<br />

Therapeutics<br />

Lillquist,<br />

Yol<strong>and</strong>a<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Medicine UBC Child & Family Research Institute glauder@cw.bc.ca www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.<br />

aspID=284<br />

Pediatrics Medicine UBC Child & Family Research Institute ylillquist@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=899753873<br />

Lim, Ken Medicine UBC Child & Family Research Institute klim@cw.bc.ca www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.<br />

aspID=78<br />

Liston, Rob Obstetrics<br />

& Gynecology<br />

Magee, Laura A. Obstetrics<br />

& Gynecology<br />

Matsell,<br />

Douglas<br />

Pediatrics Medicine UBC Child & Family Research Institute dmatsell@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=89<br />

Matsuda-<br />

Abedini, Mina<br />

UBC Child & Family Research Institute rliston@cw.bc.ca www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.<br />

aspID=79<br />

Medicine UBC Child & Family Research Institute lmagee@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=86<br />

Pediatrics Medicine UBC Child & Family Research Institute mmatsuda@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=1000012350<br />

Anesthesiology Pediatrics<br />

Pulmonary Cystic fibrosis<br />

Neonatology Cardiology, pregnancy<br />

Obstetrics / gynecology<br />

Obstetrics / gynecology<br />

Pregnancy<br />

Pregnancy<br />

Metabolic/ endocrine Growth<br />

Transplant, genitourinary<br />

Mayer, Chantel Pediatrics Medicine UBC Child & Family Research Institute N/A N/A Neonatology Neonatology<br />

Metzger, Daniel Pediatrics Medicine UBC Child & Family Research Institute dmetzger@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=91<br />

Metabolic/ endocrine Diabetes<br />

Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

243<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Nadel, Helen Radiology Medicine UBC Child & Family Research Institute hnadel@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=570168607<br />

Ochnio, Jan Pediatrics Medicine UBC Child & Family Research Institute jochnio@interchange.ubc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=899754518<br />

Osiovich,<br />

Horacio<br />

Panagiotopoulos,<br />

Dina<br />

Pediatrics Medicine UBC Child & Family Research Institute hosiovich@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=1000012356<br />

Pediatrics Medicine UBC Child & Family Research Institute dpanagiotopoulos@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=103<br />

Petty, Ross Pediatrics Medicine UBC Child & Family Research Institute rpetty@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=627046117<br />

CV / cardiology Coronary disease<br />

ID/ infection Hepatitis<br />

Neonatology Neonatology<br />

Metabolic/ endocrine Diabetes<br />

Autoimmune Rheumatology<br />

Popkin, JS Van Isl<strong>and</strong> Health Authority N/A N/A Pediatric<br />

Dermatology Psoriasis<br />

Prendiville,<br />

Julie<br />

Pediatrics Medicine UBC Child & Family Research Institute jprendiville@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=644724262<br />

Rogers, Paul Pediatrics Medicine UBC Child & Family Research Institute progers@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=111<br />

Salvarinova,<br />

Ramona<br />

Sanatani,<br />

Shubhayan<br />

Pediatrics Medicine UBC Child & Family Research Institute rsalvari@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=1000015300<br />

Pediatrics Medicine UBC Child & Family Research Institute ssanatani@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=114<br />

Cancer<br />

Metabolic/ endocrine Genetic disease<br />

CV / cardiology Coronary disease


244<br />

BRITISH COLUMBIA<br />

Pediatrics (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

S<strong>and</strong>or, George Pediatrics Medicine UBC Child & Family Research Institute gs<strong>and</strong>or@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=115<br />

Scheifele, David Pediatrics Medicine UBC Child & Family Research Institute dscheifele@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=117<br />

Schellenberg,<br />

Robert<br />

Schreiber,<br />

Richard<br />

iCAPTURE Medicine UBC Providence Health Care Research<br />

Institute<br />

bschellenberg@mrl.ubc.ca http://www.icapture.ubc.ca/<br />

who/who_bios_bob_schellenberg.shtml<br />

Pediatrics Medicine UBC Child & Family Research Institute rschreiber@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=118<br />

Schultz, Kirk Pediatrics Medicine UBC Child & Family Research Institute kschultz@interchange.ubc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=119<br />

Selby, Kathryn Pediatrics Medicine UBC Child & Family Research Institute kselby@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=382<br />

Shereck, Evan B. Pediatrics Medicine UBC Child & Family Research Institute eshereck@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=295<br />

Singh, Avash Pediatrics Medicine UBC Child & Family Research Institute ajsingh@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=384<br />

CV / cardiology<br />

ID/ infection DTP, influenza,<br />

MMR, pneumococcal<br />

Pulmonary Asthma<br />

Gastro-intestinal Liver disease<br />

Cancer, hematology,<br />

transplant<br />

Leukemia, GVHD<br />

Musculo-skeletal Dystrophy<br />

Cancer/ hematology<br />

Pulmonary RSV


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

245<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

Singhal, Ash Surgery Medicine UBC Child & Family Research Institute ash.singhal@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=384<br />

Skarsgard, Eric Surgery UBC Child & Family Research Institute eskarsgard@cw.bc.ca www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.<br />

aspID=123<br />

Skippen, Peter Pediatrics Medicine UBC Child & Family Research Institute pskippen@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=348<br />

Skowronski,<br />

Danuta<br />

Centre for<br />

Disease<br />

Control<br />

Medicine UBC BC Centre for Disease Control danuta.skowronski@bccdc.ca http://www.cdc.ubc.ca/<br />

People/DanutaSkowronski.<br />

htm<br />

Smyth, John Pediatrics Medicine UBC Child & Family Research Institute jsmyth@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=899751146<br />

Solimano,<br />

Alfonso<br />

Pediatrics Medicine UBC Child & Family Research Institute asolimano@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=899751147<br />

CNS Brain injury<br />

Surgery Fetal diagnosis/<br />

therapy, neonatology<br />

Critical care, neonatology<br />

Sepsis<br />

ID/ infection DTP, influenza<br />

Neonatology Care<br />

Neonatology Care<br />

Sorokan, Todd Fraser Health N/A N/A Critical care Sepsis, pediatrics<br />

Steinbok, Paul Surgery Medicine UBC Child & Family Research Institute psteinbok@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

CNS Brain injury<br />

researchers/researcher_detail.aspID=127<br />

Stewart, Laura Pediatrics Medicine UBC Child & Family Research Institute lstewart@cw.bc.ca https://www.directory.ubc. Metabolic/ endocrine Genetic disease<br />

ca/index.cfmpage=personD<br />

etail&row=899751150<br />

Stockler, Sylvia Pediatrics Medicine UBC UBC Campus sstockler@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=255<br />

Metabolic/ endocrine Genetic disease


246<br />

BRITISH COLUMBIA<br />

Pediatrics (cont’d)<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Straatman,<br />

Lynn<br />

Strahlendorf,<br />

Caron<br />

Pediatrics Medicine UBC Providence Health Care Research<br />

Institute<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

lstraatman@providencehealth.bc.ca<br />

http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=296<br />

Pediatrics Medicine UBC Child & Family Research Institute cstrahlendorf@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=261<br />

Synnes, Anne Pediatrics Medicine UBC Child & Family Research Institute asynnes@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=129<br />

Transplant, CV/<br />

cardiology<br />

Tan Dy, C Van Isl<strong>and</strong> Health Authority N/A N/A Neonatology<br />

Tucker, Lori Pediatrics Medicine UBC Child & Family Research Institute ltucker@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=134<br />

Von Dadelszen,<br />

Peter<br />

Medicine UBC Child & Family Research Institute pdadelszen@cw.bc.ca; pvd@<br />

cw.bc.ca<br />

Obstetrics<br />

& Gynecology<br />

http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=140<br />

Cancer<br />

ID/ infection Fungal<br />

Autoimmune,<br />

genitourinary<br />

Obstetrics / gynecology,<br />

neonatology<br />

Rheumatology,<br />

renal<br />

Pregnancy, neonatology<br />

Wambera, Kati Pediatrics Medicine UBC Child & Family Research Institute N/A N/A CNS Brain/CNS<br />

Weiss, Margaret Psychiatry Medicine UBC Child & Family Research Institute margaret.weiss@me.com http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=145<br />

CNS Mental health<br />

ARDS<br />

Wensley, David Pediatrics Medicine UBC Child & Family Research Institute dwensley@cw.bc.ca https://www.directory.ubc.<br />

ca/index.cfmpage=personD<br />

etail&row=853018927<br />

White, Colin Pediatrics Medicine UBC Child & Family Research Institute cwhite@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=247<br />

Pulmonary, critical<br />

care<br />

Genitourinary Renal


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

247<br />

INVESTIGATOR DEPT FACULTY AFFILI-<br />

ATED UNI-<br />

VERSITY<br />

Wilcox, Pearce<br />

G.<br />

Medicine Medicine UBC Providence Health Care Research<br />

Institute<br />

INSTITUTION EMAIL URL DISEASE SPECIALTY SPECIFIC DISEASE/<br />

CONDITION<br />

pwilcox@providencehealth.<br />

bc.ca<br />

http://www.icapture.ubc.ca/<br />

who/who_bios_pearce_wilcox.shtml<br />

Wong, Peter Pediatrics Medicine UBC Child & Family Research Institute pwong@interchange.ubc.ca www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_detail.<br />

aspID=383<br />

Wu, John K. Pediatrics Medicine UBC Child & Family Research Institute jwu@cw.bc.ca http://www.cfri.ca/our_research/researchers/search_<br />

researchers/researcher_detail.aspID=249<br />

Yeung-Lai-Wah,<br />

John<br />

Cardiology<br />

Medicine UBC Providence Health Care Research<br />

Institute<br />

jayeung@axion.net http://www.providenceresearch.ca/directory/index.<br />

aspx<br />

Pulmonary Cystic fibrosis,<br />

asthma, COPD<br />

CNS Epilepsy/ seizures<br />

Hematology Genetic disease, infection,<br />

thrombosis/<br />

coagulation<br />

CV / cardiology Coronary disease


248<br />

BRITISH COLUMBIA<br />

APPENDICES 7-13<br />

TABLE OF CONTENTS<br />

Appendix 7.<br />

General <strong>and</strong> Patient Populations 249<br />

Appendix 8.<br />

Provincial <strong>and</strong> National Patient Registries Involving B.C. Investigators 254<br />

Appendix 9.<br />

Healthcare Research Centres 257<br />

Appendix 10.<br />

National <strong>and</strong> International Networks Which Have B.C. <strong>Clinical</strong> Investigators as<br />

Pivotal Players or Members 284<br />

Networks In Which B.C.’s <strong>Clinical</strong> Investigators Play a Pivotal Role 284<br />

Networks In Which B.C.’s <strong>Clinical</strong> Investigators Are Members 289<br />

Appendix 11.<br />

Independent <strong>Clinical</strong> <strong>Trials</strong> Service Companies 292<br />

Appendix 12.<br />

<strong>Preclinical</strong> Studies Service Organizations 306<br />

Appendix 13.<br />

Acknowledgements 311


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249<br />

APPENDIX 7. GENERAL AND PATIENT POPULATIONS<br />

This Appendix contains three tables:<br />

1. B.C. General Population 2008 (A1)<br />

2. Ethnic Makeup of B.C. Population 2006 (A2)<br />

3. Patient <strong>and</strong> Addiction Populations in B.C. (includes information on numerous diseases) (A3).<br />

TABLE A1. B.C. General Population 2008 ’000s 1<br />

All ages 0-14 15-64 65+<br />

Both Sexes<br />

4,381.6 686.2 3,059.1 636.4<br />

Males<br />

2,172.8 353.7 1,528.5 290.6<br />

Females<br />

2,208.8 332.5 1,530.6 345.8<br />

TABLE A2. Ethnic Makeup of B.C. Population 2006 2<br />

Total Population 2006<br />

4,074,385 (lower than<br />

previous table as 3 years<br />

earlier)<br />

Total visible minority population 1,008,855 (24.8%)<br />

Chinese 407,225<br />

South Asian 262,290<br />

First Nations (Aboriginals) 3 196,075<br />

Filipino 88,075<br />

Korean 50,490<br />

Southeast Asian 40,690<br />

Japanese 35,060<br />

West Asian 29,810<br />

Latin American 28,960<br />

Black 28,315<br />

Arab 8,635<br />

Multiple visible minority 25,415<br />

Visible minority, not included elsewhere 3,880<br />

1<br />

Statistics Canada. http://www40.statcan.gc.ca/l01/pro01/pro110-eng.htm. Accessed October 22, 2009. See also Statistics Canada.<br />

http://www40.statcan.gc.ca/l01/cst01/demo31a-eng.htm. Accessed December 6, 2009.<br />

2<br />

Statistics Canada. http://www40.statcan.gc.ca/l01/cst01/demo52c-eng.htm. Accessed December 6, 2009.<br />

3<br />

www40.statcan.gc.ca/l01/cst01/demo40c-eng.htm. Accessed March 9, 2010. These are people who reported an Aboriginal identity.<br />

They are not included in the 1,008,855 visible minority population.


250<br />

BRITISH COLUMBIA<br />

TABLE A3. Patient <strong>and</strong> Addiction Populations in B.C. 4<br />

Disease Area<br />

Population Information<br />

Cancer New Cases/Year 5<br />

All cancer types 21,190<br />

Prostate 3,390<br />

Lung 2,870<br />

Breast 2,852<br />

Colon 1,728<br />

Bladder/bladder in situ 1,000<br />

Rectum <strong>and</strong> Anus 941<br />

Non-Hodgkin’s Lymphoma 886<br />

Melanoma 765<br />

Leukemia 603<br />

Uterus 541<br />

Pancreas 495<br />

Oral (Buccal Cavity <strong>and</strong> Pharynx) 458<br />

Brain <strong>and</strong> CNS 306<br />

Endocrine Gl<strong>and</strong>s 311<br />

Ovary 280<br />

Multiple Myeloma 264<br />

Cervix 163<br />

Soft Tissue (incl. Heart) 133<br />

Hodgkin’s Lymphoma 99<br />

Kidney 35<br />

Mesothelioma 72<br />

Eye 41<br />

Bone 38<br />

Total B.C. cancer prevalence over two years 21,700 6<br />

Total B.C. cancer prevalence over five years 45,400 6<br />

Total B.C. cancer prevalence over ten years 72,300 6<br />

CNS Conditions<br />

Alcohol addiction 344,000 prevalence 7<br />

4<br />

The type of population information varies for different diseases, based on data source.<br />

5<br />

BC Cancer Registry Statistics 2007 prepared by Population Oncology March 2009. Includes BC residents at diagnosis with any invasive<br />

cancer, excluding non-melanoma skin cancers (BCC, SCC - site C44: histology 8050-8084, 8090-8110). www.bccancer.bc.ca/NR/<br />

rdonlyres/27D69A84-8911-4B97-9073-96F5CEC13961/34420/NumberofCancerDiagnosis1.pdf. Accessed September 29, 2009.<br />

6<br />

Canadian Cancer Statistics, 2009. Canadian Cancer Society. B.C. prevalence (survivors over two, five, <strong>and</strong> 10 years) is assumed to be<br />

approx. 10% of total Canadian prevalence.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

251<br />

Disease Area<br />

Population Information<br />

Alzheimer’s Disease <strong>and</strong> related disorders<br />

Over 1,200 registered patients<br />

in UBC Clinic for Alzheimer’s<br />

Disease <strong>and</strong> Related Disorders 8<br />

Bipolar Disorder<br />

Approx. 400 registered 8 with<br />

the UBC Mood Disorders Clinic<br />

(www.ubcmood.ca)<br />

Depression <strong>and</strong> anxiety 300,000 patients per year 9<br />

Illegal drug addiction 33,000 prevalence 7<br />

Multiple sclerosis (MS)<br />

Over 4,500 registered with the<br />

UBC MS clinic 8<br />

Parkinson's Disease (PD) <strong>and</strong> Parkinson-like disorders (PLD) 1,100 with typical PD, 400<br />

patients with PLD, 500 – 1,000<br />

dystonia patients registered<br />

with the UBC Movement<br />

Disorders Clinic 8<br />

Smokers 700,000 prevalence 7<br />

Youth ADHD population 30,900 prevalence 10<br />

Infectious Diseases New Case Reports in 2008<br />

(except for AIDS) 11<br />

AIDS 78 (2007)<br />

Amebiasis 338<br />

Campylobacteriosis 1,635<br />

Chlamydia 10,629<br />

Cryptosporidiosis 115<br />

Cyclosporiasis 32<br />

E. coli, Verotoxigenic 114<br />

Ciardiasis 632<br />

Gonorrhea 1,391<br />

Hepatitis A 39<br />

Hepatitis B (acute) 29<br />

Hepatitis C 2,479<br />

7<br />

Stepping Forward. Improving Addiction Care in British Columbia. BC Medical Association, 2009. http://www.bcma.org/files/Addiction_Stepping_Forward.pdf.<br />

p. 5. Accessed October 22, 2009.<br />

8<br />

Neurosciences <strong>Asset</strong> <strong>Map</strong> British Columbia. www.investbc.com/assetmaps.htm. Accessed October 15, 2009.<br />

9<br />

Stepping Out of the Shadows. Collaborating to Improve Services for Patients with Depression. https://www.bcma.org/files/Depression_paper_aug13.pdf.<br />

p. 12. Accessed October 22, 2009.<br />

10<br />

BC Ministry of Children <strong>and</strong> Family Development, 2003. Child <strong>and</strong> Youth Mental health Plan for British Columbia. Cited “Your Attention<br />

Please”. Improving Access for ADHD Patients. BC Medical Association, 2009. http://www.bcma.org/files/ADHD_paper.pdf.<br />

Accessed October 22, 2009.<br />

11<br />

http://www.bccdc.ca/NR/rdonlyres/59BFCFBB-933D-4337-9305-E3E5FF30D272/0/EPI_Report_CDAnnual2008_20090806.pdf. Accessed<br />

November 4, 2009.<br />

12<br />

B.C. Centre for Excellence in HIV/AIDS. http://www.cfenet.ubc.ca/content.phpid=18. Accessed November 22, 2009.


252<br />

BRITISH COLUMBIA<br />

TABLE A3. Patient <strong>and</strong> Addiction Populations in B.C. (cont’d)<br />

Infectious Diseases New Case Reports in 2008<br />

(except for AIDS) 11<br />

Haemophilus Influenza b, invasive 12<br />

HIV 350 (prevalence: ~10,400 12 )<br />

Listeriosis 23<br />

Lyme 6<br />

Malaria 35<br />

Meningococcal Disease, invasive 20<br />

Mumps 108<br />

Paratyphoid fever 29<br />

Pertussis 231<br />

Pneumococcal Disease, invasive 402<br />

Rubella 1<br />

Salmonellosis 922<br />

Shigellosis 204<br />

Streptococcal group A, invasive 260<br />

Syphilis (infectious) 328<br />

Tuberculosis 303<br />

Typhoid Fever 45<br />

Vibrio parahaemolyticus 23<br />

Yersiniosis 569<br />

West Nile Virus 1<br />

Other Conditions<br />

Arthritis 555,000 prevalence (2008) 13<br />

Asthma 280,600 prevalence (2008) 13<br />

Diabetes 187,000 prevalence (2008) 13<br />

Hypertension 554,900 prevalence (2008) 13<br />

Heart transplants 17/ year (2008)<br />

Kidney transplants 167/year (2008) 14<br />

Liver transplants 47/year (2008) 14<br />

Other organ transplants (lung, pancreas) 35/yr 2008 14<br />

Obesity<br />

18% of men, 20% of women<br />

(prevalence 2004) 15<br />

13<br />

Statistics Canada. http://www40.statcan.gc.ca/l01/pro01/pro110-eng.htm. Accessed October 22, 2009.<br />

14<br />

http://www.transplant.bc.ca/stats_faqs_main.htm#stat. Accessed October 22, 2009.


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253<br />

Disease Area<br />

Population Information<br />

Children 16<br />

Total treated/ year at B.C. Children’s Hospital > 72,000<br />

Cancer<br />

900 treated/yr<br />

Pediatric intensive care<br />

1,200/year<br />

Open heart surgery<br />

140/year<br />

Number of births 44,554 in 2008/9 17<br />

Pre-term births (< 37 weeks gestation) 6.32% 18<br />

15<br />

Statistics Canada. www.statcan.gc.ca/pub/82-620-m/2005001/c-g/adults-adutles/4053576-eng.htm. Accessed March 9, 2010.<br />

16<br />

www.bcchildrens.ca/AboutUs/BCCH/Facts.htm. Accessed November 6, 2009.<br />

17<br />

Statistics Canada. www40.statcan.gc.ca/l01/cst01/demo04a-eng.htm. Accessed March 9, 2010. Data refer to the 10 year period Jan<br />

1981-Dec 2000 (more recent data were not found).<br />

18<br />

www.vs.gov.bc.ca/stats/pdf/ChartingBirthOutcomeReport.pdf. Accessed March 9, 2010.


254<br />

BRITISH COLUMBIA<br />

APPENDIX 8. PROVINCIAL AND NATIONAL PATIENT REGISTRIES INVOLVING<br />

B.C. INVESTIGATORS<br />

Name of Registry/ URL B.C. Contact Description<br />

Cancer<br />

B.C. Cancer Registry, BCCA<br />

(www.bccancer.bc.ca/HPI/CancerStatistics/<br />

default.htm#bccanreg)<br />

National Marrow Donor Program (www.<br />

marrow.org)<br />

Cardiovascular/ Cardiology<br />

B.C. Cardiac Registry (www.phsa.ca/NR/<br />

rdonlyres/3B51D4FB-5384-4F26-AA50-7-<br />

B29443DB48B/27283/Cardiac_Strategic_<br />

Plan_Updated_final.pdf)<br />

Sharon Tamaro, Director<br />

stamaro@bccrc.ca<br />

Tel: 604 675 8070<br />

Clay Smith. Director Leukemia/BMT<br />

Program of B.C.<br />

clsmith@bccancer.bc.ca<br />

Tel: 604-875-4863<br />

Ron Carere. Regional Director of the<br />

Cardiac Program for VCH.<br />

rcarere@providencehealth.bc.ca<br />

Tel: 604 806-9139<br />

BRIEF PCI Registry (No URL) Graham Wong, Coronary Care Unit,<br />

Vancouver General Hospital<br />

gcwong@telus.net<br />

Tel: 604-875-5735<br />

Carotid Registry (No URL) Jackie Saw, Cardiology, Vancouver General<br />

Hospital<br />

jsaw@interchange.ubc.ca<br />

Tel: 604 875-5547<br />

Has been monitoring the impact of cancer in the province since 1969. Registry tracks cancer<br />

incidence, diagnosis, mortality, gender <strong>and</strong> age to determine the trend of cancer B.C. as<br />

different patterns are seen in different age groups <strong>and</strong> sometimes for the same cancer in<br />

different sexes. This information identifies the most deadly cancer diseases <strong>and</strong> targets high<br />

risk groups.<br />

The Leukemia/BMT Program of B.C. contributes to this North American registry.<br />

Operated by B.C. Cardiac Registry <strong>and</strong> Evaluation Services at the PHSA to record information<br />

about patients going through the cardiac care system. The BCCR database contains<br />

information such as demographics, nature of cardiac surgeries, as well as diagnostic <strong>and</strong><br />

interventional catheterization procedures. This is one of the most comprehensive medical<br />

databases in Canada; it records over 30,000 diagnostic procedures per year <strong>and</strong> contains more<br />

than 10 years of high-quality cardiac catheterization <strong>and</strong> adult open heart surgery data. The<br />

data is gathered from all hospitals with catheterization labs in B.C. It contains data covering<br />

60 cardiologists, 17 cardiac surgeons <strong>and</strong> 6 sites (www.coe.ubc.ca/industry/projects/2005/<br />

cardiac_registry.pdf).<br />

A localized database of inflammatory markers prior to <strong>and</strong> post uncomplicated percutaneous<br />

coronary intervention (PCI) (a.k.a. angioplasty) followed by a brief infusion of eptifibatide.<br />

A single-centre prospective carotid intervention registry on carotid stenting in symptomatic<br />

coronary disease. Contains information on clinical, procedural, lesion <strong>and</strong> other characteristics.


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255<br />

Name of Registry/ URL B.C. Contact Description<br />

Fibro Muscular Dysplasia (FMD) Registry (No<br />

URL)<br />

CNS<br />

Canadian Epilepsy Database <strong>and</strong> Registry<br />

(CEDAR) (No URL; see www.ncbi.nlm.nih.gov/<br />

pubmed/9827243)<br />

Canadian Pediatric Ischemic Stroke Registry<br />

(No URL; see www.cfri.ca/our_research/<br />

researchers/search_researchers/researcher_<br />

detail.aspID=387)<br />

Rick Hansen Spinal Cord Injury Registry<br />

(www.rickhansenregistry.org)<br />

Christopher Buller, Interventional<br />

Cardiologist, Vancouver General & St.<br />

Paul’s Hospitals<br />

janet.crocombe@vch.ca (administrator)<br />

Tel: 604 875-4111 x 69821<br />

Mary Connolly, Head of Division of<br />

Pediatric Neurology, BCCH.<br />

mconnolly@cw.bc.ca<br />

Tel: 604-875-2000 x 3512.<br />

Contact: Bruce Bjornson, B.C. Children’s<br />

Hospital (BCCH)<br />

bbjornson@cw.bc.ca<br />

Tel: 604-875-2345 x 3510<br />

Lvl 6, 818 West 10th Avenue<br />

Vancouver, B.C., V5Z 1M9<br />

Tel: 604-707-2100<br />

Infectious Diseases<br />

Canadian Perinatal HIV Database John (Jack) Forbes, BCCH<br />

jforbes@cw.bc.ca<br />

Tel: 604-875-2212<br />

Pulmonary<br />

Asthma Registry at The Lung Centre, VGH Mark FitzGerald, Director of the Centre for<br />

<strong>Clinical</strong> Epidemiology <strong>and</strong> Evaluation<br />

markf@interchange.ubc.ca<br />

Tel: 604-875-4565<br />

Localized registry containing demographic, clinical, coronary angiographic <strong>and</strong> other information<br />

on patients with Coronary Fibro Muscular Dysplasia.<br />

A comprehensive multicentre epilepsy database, developed to study the impact of medical,<br />

psychological, social, demographic <strong>and</strong> other factors on epilepsy in Canada. It can also be<br />

used locally in the clinic for office record keeping, automated printout of a referral letter or<br />

graphing seizures <strong>and</strong> other data over time. The data in CEDAR are similar to those found in<br />

the patient’s chart. There are 20 participating centres across Canada which have entered data<br />

on over 8,000 adult <strong>and</strong> pediatric epilepsy patients. The information is available for research<br />

purposes to centres entering data as well as to academic researchers, the pharmaceutical<br />

industry <strong>and</strong> government agencies.<br />

The purpose of this unique project is to:<br />

• Collect comprehensive population-based data on pediatric (up to 18 yrs old) ischemic stroke<br />

(arterial ischemic stroke <strong>and</strong> sinus thrombosis)<br />

• Provide information, including prospective update of chart information, for r<strong>and</strong>omized<br />

clinical trials testing treatments for childhood stroke.<br />

The recording period is January 1, 1992 to present <strong>and</strong> 16 pediatric tertiary care centres<br />

participate. Two hundred <strong>and</strong> twenty patients with stroke or cerebrovascular disease (131 AIS,<br />

32 SVT, 57 other cerebrovascular diseases) have been identified at BCCH.<br />

National database based in Vancouver that tracks specific outcome measures for people with<br />

traumatic forms of SCI <strong>and</strong> provides invaluable research data.<br />

National surveillance program of HIV exposed <strong>and</strong> infected children, which is reported annually<br />

by the Public Health Agency of Canada (see www.cfri.ca/our_research/researchers/<br />

search_researchers/researcher_detail.aspID=41).<br />

Localized registry of asthma patients.


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BRITISH COLUMBIA<br />

APPENDIX 8. Provincial And National Patient Registries Involving B.C. Investigators (cont’d)<br />

Name of Registry/ URL B.C. Contact Description<br />

Cystic Fibrosis Foundation Patient Data<br />

Registry (no URL)<br />

COPD Registry at The Lung Centre, VGH (No<br />

URL)<br />

Other<br />

B.C. Trauma Registry (www2.<br />

itssti.hc-sc.gc.ca/clf/clfinven-<br />

tory.nsf/idview/030204164816-KC-<br />

KROpenDocument&lang=E)<br />

CORR (Canadian Organ Replacement Register)<br />

Transplant Registry<br />

(http://www.cihi.ca/corr)<br />

Integrated Public Health Information<br />

System (iPHIS)<br />

(www.phac-aspc.gc.ca/php-psp/ciphs-eng.<br />

php#wiphis)<br />

ARCHIVE (International Registry for Childhood<br />

Vasculitis)<br />

N/A Canadian on-line patient data surveillance system (see www.gcdisclosure-divulgationsc.<br />

phac-aspc.gc.ca/phac/pd/pd_grants.nsf/WEBbydetails/4D1B39E580E78B9F8525734000500<br />

2ADOpenDocument&L=E&).<br />

Jeremy Road, Medical Director of the<br />

COPD Clinic<br />

jroad@interchange.ubc.ca<br />

Tel: 604 875-4241<br />

Sharon Kasic, VGH<br />

sharon.kasic@vch.ca<br />

Tel: 604-875-4748<br />

John Gill, Chair, CORR Transplant Registry,<br />

St Paul’s Hospital<br />

jgill@providencehealth.bc.ca<br />

Tel: 604-806-9048<br />

Dilma S<strong>and</strong>rin, iPHIS Program Manager,<br />

BCCDC<br />

Tel: 604-707-2501<br />

David Cabral, BCCH.<br />

dcabral@cw.bc.ca<br />

Tel: 604-875-2437.<br />

Localized registry of COPD patients.<br />

Collects <strong>and</strong> maintains data on all trauma patients admitted to any of the nine trauma receiving<br />

facilities in B.C. The primary purpose is to improve <strong>and</strong> maintain the quality of patient<br />

care. Other purposes of this data source are for epidemiology, research, planning, injury<br />

surveillance; <strong>and</strong> contributing to injury prevention programs.<br />

CORR records, analyzes <strong>and</strong> reports on the level of activity <strong>and</strong> outcomes of vital organ transplantation<br />

<strong>and</strong> renal dialysis activities in Canada. It keeps statistics on transplant numbers,<br />

donor numbers <strong>and</strong> waiting lists.<br />

An automated, integrated, client health record <strong>and</strong> reporting system that supports public<br />

health provider interventions, tracking, follow-up, case management, <strong>and</strong> reporting. iPHIS<br />

includes immunization tracking, communicable disease case management, <strong>and</strong> surveillance<br />

components <strong>and</strong> is designed to be used centrally, providing secure access to one client<br />

record by multiple public health providers <strong>and</strong> programs <strong>and</strong> allowing communicable disease<br />

surveillance <strong>and</strong> immunization information to be shared. Data available for project-specific<br />

research purposes.<br />

US/Canadian registry of children with Wegener’s Granulomatosis <strong>and</strong> related small-medium<br />

vessel chronic vasculitis populated by all pediatric rheumatology centres (see www.vasculitisfoundation.org/registryofchildrenwithWG<strong>and</strong>relatedvasculitides).<br />

PROMIS<br />

(www.bcrenalagency.ca/professionals/<br />

promis/default.htm)<br />

Mirek Piaseczny, B.C. Provincial Renal<br />

Agency<br />

mpiaseczny@bcpra.ubc.ca<br />

Tel: 604-806-8647<br />

Database of all nephrology patients on dialysis, with CKD <strong>and</strong> before/ after transplantation.<br />

Contains all patient records <strong>and</strong> outcomes from B.C.’s 37 renal units. Care providers can access<br />

information about a patient’s medical care, no matter where the care is delivered.


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257<br />

APPENDIX 9. HEALTHCARE RESEARCH CENTRES<br />

The following table has been split into different categories as follows:<br />

1. Broad-based<br />

• Providence Health Care Research Institute<br />

• Vancouver Coastal Health Research Institute (VCHRI)<br />

• British Columbia Institute of Technology (BCIT) School of Health <strong>Sciences</strong><br />

2. Neurosciences, including mental health <strong>and</strong> addiction<br />

• Brain Research Centre, VCHRI<br />

• International Collaboration On (Spinal Cord) Repair Discoveries (ICORD) VCHRI<br />

• Down Syndrome Research Foundation<br />

• B.C. Mental Health <strong>and</strong> Addictions Research Institute (BCMHARI)<br />

• Centre for Addictions Research of B.C.<br />

• Centre for Applied Research in Mental Health & Addiction (CARMHA)<br />

3. Cancer<br />

• B.C. Cancer Research Centre, BCCA<br />

• Functional Imaging Program (FIP), BCCA<br />

• The Vancouver Prostate Centre including theTranslational Research Initiative for Accelerated Discovery<br />

<strong>and</strong> Development (PC-TRIADD), VCHRI<br />

• Finl<strong>and</strong>ia Natural Pharmacy<br />

• InspireHealth<br />

4. Infectious diseases<br />

• B.C. Centre for Disease Control<br />

• B.C. Centre for Excellence in HIV/AIDS<br />

• CIHR Canadian HIV <strong>Trials</strong> Network<br />

5. Cardiovascular<br />

• Healthy Heart Centre (HHC), St Paul’s Hospital<br />

• The James Hogg iCAPTURE Centre for Cardiovascular <strong>and</strong> Pulmonary Research (Heart Lung Institute)<br />

6. Pulmonary<br />

• Centre for Respiratory & Critical Care Medicine, VCHRI<br />

• Pacific Lung Health Centre<br />

7. Autoimmune diseases<br />

• Arthritis Research Centre of Canada, VGH<br />

• Immunity & Infection Research Centre, VCHRI<br />

• Prevention of Organ Failure Centre of Excellence (PROOF)


258<br />

BRITISH COLUMBIA<br />

APPENDIX 9. Healthcare Research Centres (cont’d)<br />

8. Other disease-based<br />

• B.C. Provincial Renal Agency<br />

• Centre for Hip Health & Mobility, VCHR<br />

• The Department of Dermatology <strong>and</strong> Skin Science, UBC<br />

9. Child <strong>and</strong> youth health<br />

• Child <strong>and</strong> Family Health Research Institute (CFRI)<br />

• Children’s Health Policy Centre<br />

• Department of Pediatrics, UBC<br />

• The McCreary Centre Society<br />

10. Women’s health<br />

• B.C. Centre of Excellence for Women’s Health<br />

• Centre for Menstrual Cycle <strong>and</strong> Ovulation Research<br />

• Women’s Health Research Institute (WHRI)<br />

• The Women’s Health Research Network<br />

11. Ageing <strong>and</strong> gerontology<br />

• Centre on Ageing<br />

• Centre for Healthy Ageing at Providence, St. Paul’s<br />

• Centre for Research on Personhood in Dementia<br />

• Gerontology Research Centre<br />

12. Rural <strong>and</strong> aboriginal health<br />

• Centre for Aboriginal Health Research (CAHR)<br />

• New Emerging Team for Health in Rural & Northern British Columbia<br />

13. Other health research<br />

• Centre for Blood Research, UBC<br />

• Centre for Molecular Medicine <strong>and</strong> Therapeutics, CFRI<br />

• Centre for Translational <strong>and</strong> Applied Genomics (CTAG), PHSA<br />

• Institute of Applied Physical Activity <strong>and</strong> Health Research, UVic<br />

• Michael Smith Genome <strong>Sciences</strong> Centre (GSC), BCCA<br />

• The Dr. Tong Louie Living Laboratory,SFU<br />

• UVic - Genome B.C. Proteomics Centre<br />

• University of Victoria School of Health Information Science (HIS)<br />

• The Vancouver Prostate Centre - Genome B.C. Microarray Facility


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259<br />

14. Health policy, epidemiology, <strong>and</strong> health economics<br />

• Centre for <strong>Clinical</strong> Epidemiology & Evaluation VCHRI<br />

• Centre for Health Evaluation <strong>and</strong> Outcome <strong>Sciences</strong> (CHEOS)<br />

• CIHR Canadian HIV <strong>Trials</strong> Network<br />

• Collaboration for Outcomes Research <strong>and</strong> Evaluation (CORE), UBC<br />

• Centre of Excellence for Simulation Education & Innovation (CESEI)<br />

• Centre for International Health<br />

• Division of Mathematical Modeling, UBC/ B.C. Centre for Disease Control (BCCDC)<br />

• Pharmaceutical Outcomes <strong>and</strong> Policy Innovations, Children’s <strong>and</strong> Women’s Health Centre of B.C.<br />

• University of Victoria Pharmaceutical Outcomes <strong>and</strong> Policy Innovation<br />

• UBC Centre for Health Services <strong>and</strong> Policy Research (CHSPR)<br />

15. Environmental health<br />

• School of Environmental Health, UBC<br />

• The B.C. Environmental <strong>and</strong> Occupational Health Research Network.


260<br />

BRITISH COLUMBIA<br />

APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

1. BROAD-BASED RESEARCH CENTRES<br />

Providence Health<br />

Care Research Institute<br />

www.providencehealthcare.org/research/index.html<br />

Vancouver Coastal<br />

Health Research Institute<br />

(VCHRI)<br />

www.vchri.ca<br />

11th Floor – 1190 Hornby Street<br />

Vancouver, B.C. V6Z 2K5<br />

Office of Research Services<br />

Tel: 604-806-8567<br />

Fax: 604-806-8568<br />

Erin Cherban<br />

Tel: 604-806-8871<br />

erin_cherban@mail.cheos.ubc.ca<br />

or<br />

Gail DiBernardo<br />

Tel: 604-806-9608<br />

gdibernardo@providencehealth.bc.ca<br />

Administration Office<br />

Rm 100 - Willow Chest Centre<br />

2647 Willow Street<br />

Vancouver, B.C. V5Z 3P1<br />

Tel: 604.875.4372 -<br />

Fax: 604.875.5684 -<br />

research@vch.ca<br />

Contact: Karen Donaldson, Manager,<br />

VCHRI<br />

Tel: 604.875.5470<br />

karen.donaldson@vch.ca<br />

PHCRI conducts research in the areas of heart, lung <strong>and</strong> kidney care, HIV/AIDS, critical care, mental health <strong>and</strong> addiction <strong>and</strong> other urban<br />

health issues, <strong>and</strong> elder care research.<br />

PHCRI focus is on research that pursues real life health solutions for the patients <strong>and</strong> residents cared for at Providence Health Care <strong>and</strong><br />

across B.C.. PHCRI has over 100 principle investigators <strong>and</strong> several Research Centres whose areas of research are directly aligned with the<br />

priority care programs of Providence Health Care:<br />

• James Hogg iCAPTURE Centre for Cardiovascular <strong>and</strong> Pulmonary Research<br />

• Centre for Health Evaluation <strong>and</strong> Outcome <strong>Sciences</strong><br />

• B.C. Centre for Excellence in HIV/AIDS<br />

• Centre for Healthy Ageing at Providence.<br />

PHCRI also houses two National research programs:<br />

• CIHR Canadian HIV <strong>Trials</strong> Network<br />

• Centre of Excellence for Commercialization <strong>and</strong> Research: The Prevention of Organ Failure Centre of Excellence (PROOF Centre).<br />

<strong>Clinical</strong> research at Vancouver General Hospital (<strong>and</strong> UBC Hospital) is conducted by the Vancouver Coastal Health Research Institute<br />

(VCHRI), a partnership between Vancouver Coastal Health Authority (VCH) <strong>and</strong> UBC. It fosters <strong>and</strong> promotes research <strong>and</strong> innovation across<br />

the entire VCH.<br />

VCHRI is one of Canada’s top funded health sciences research institutes. With a focus on translational research <strong>and</strong> innovation, the Institute<br />

supports <strong>and</strong> develops programs <strong>and</strong> initiatives across the health spectrum <strong>and</strong> at several sites <strong>and</strong> research centres in B.C.:<br />

• Brain Research Centre: focuses on mechanisms of brain function <strong>and</strong> neurological disorders of the brain including multiple sclerosis,<br />

Parkinson’s disease, mood disorders, <strong>and</strong> schizophrenia.<br />

• Centre for <strong>Clinical</strong> Epidemiology & Evaluation: supports clinical research <strong>and</strong> evaluation of clinical programs <strong>and</strong> provides expertise in<br />

clinical research methodology <strong>and</strong> statistics to other VCHRI investigators <strong>and</strong> health care policy makers<br />

• Centre for Hip Health & Mobility: brings together researchers from a wide range of disciplines to investigate <strong>and</strong> treat hip fractures <strong>and</strong><br />

osteoarthritis, <strong>and</strong> create new surgical solutions.<br />

• Centre for Respiratory & Critical Care Medicine: research to improve prevention, diagnosis, <strong>and</strong> treatment of respiratory <strong>and</strong> critical care<br />

illnesses including lung cancer, asthma, chronic obstructive pulmonary disorder, sleep apnea, <strong>and</strong> tuberculosis.<br />

• ICORD: International Collaboration on (spinal cord) Repair Discoveries: research into surgical advances, <strong>and</strong> new approaches in rehabilitation<br />

leading to better health outcomes for people with spinal cord injury.<br />

• mmunity & Infection Research Centre: works to underst<strong>and</strong> the immune mechanisms that both fight infectious diseases <strong>and</strong> cause immune<br />

disorders<br />

• The Vancouver Prostate Centre: focuses its efforts on fighting prostate cancer through improved underst<strong>and</strong>ing of prevention, diagnosis,<br />

<strong>and</strong> treatment, as well as patient education.


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261<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

British Columbia<br />

Institute of Technology<br />

(BCIT)<br />

School of Health <strong>Sciences</strong><br />

No URL<br />

3700 Willingdon Avenue<br />

Burnaby, B.C. V5G 3H2<br />

Tel: 604-434-5734<br />

Contact: Franca MacInnes, Operations<br />

Manager<br />

Tel: 604-432-8855<br />

Franca_MacInnes@bcit.ca<br />

Applied research contact:<br />

BCIT Applied Research Liaison Office<br />

(ARLO)<br />

Wing E - 4355 Mathissi Place<br />

Burnaby, B.C. V5G 4S8<br />

Tel: 604-456-1032<br />

Fax: 778-329-0314<br />

ARLO@bcit.ca<br />

2. NEUROSCIENCE SPECIFIC RESEARCH INSTITUTES<br />

Brain Research Centre<br />

(BRC)<br />

VCHRI<br />

www.brain.ubc.ca<br />

International Collaboration<br />

On (Spinal Cord)<br />

Repair Discoveries<br />

(ICORD)<br />

VCHRI<br />

icord.org/contact-us/<br />

2211 Wesbrook Mall<br />

Vancouver B.C. V6T 2B5<br />

Tel: 604-822-7246<br />

Fax: 604-822-0361<br />

info@brain.ubc.ca<br />

Communications or media inquiries:<br />

communications@brain.ubc.ca<br />

Blusson Spinal Cord Centre<br />

818 West 10th Avenue<br />

Vancouver B.C. V5Z 1M9<br />

Contact: Lowell McPhail, Operations<br />

Manager<br />

mcphail@icord.org/<br />

Tel: 604-675-8811<br />

BCIT conducts grant-funded <strong>and</strong> industry-sponsored applied research <strong>and</strong> development focused on solving industry’s challenges. Bringing<br />

together multi-disciplinary teams from a range of research areas spanning trades <strong>and</strong> technical expertise, BCIT researchers create practical<br />

applied research solutions that can be transformed immediately into commercially relevant products, services <strong>and</strong> applications.<br />

BCIT research is primarily motivated by the creation of direct <strong>and</strong> indirect benefits for students. Applied research provides students with<br />

practical learning opportunities, <strong>and</strong> produces outcomes that further economic success <strong>and</strong> employment opportunities.<br />

BCIT Research projects <strong>and</strong> initiatives in the healthcare sector are currently taking place in the following areas:<br />

• Aging <strong>and</strong> Disability<br />

• Biotechnology<br />

• Health <strong>and</strong> Safety<br />

• Health Technology<br />

• Health Informatics<br />

• Medical <strong>and</strong> Assistive Device Development<br />

• Medical Imaging<br />

• Natural Health Products.<br />

BRC focuses on mechanisms of brain function <strong>and</strong> neurological disorders of the brain including multiple sclerosis, Parkinson’s disease,<br />

mood disorders, <strong>and</strong> schizophrenia.<br />

BRC addresses six areas of neuroscience research:<br />

• Neurodegeneration (Alzheimer’s, Parkinson’s, ALS)<br />

• Multiple sclerosis<br />

• Mental health <strong>and</strong> addictions<br />

• Stroke<br />

• Neurotrauma<br />

• Vision.<br />

BRC supports specialized laboratories that incorporate medical science’s most recent advances in technology at the cellular <strong>and</strong> molecular<br />

levels. The Brain Research Centre is committed to developing new technologies to aid diagnosis <strong>and</strong> treatment. Two key areas of technology<br />

at the Centre are diagnostic imaging, which is the observation of activity of the living brain, <strong>and</strong> genomics, which is the application of<br />

the newest tools in gene technology <strong>and</strong> gene therapy.<br />

ICORD undertakes research into surgical advances, <strong>and</strong> new approaches in rehabilitation leading to better health outcomes for people with<br />

spinal cord injury. ICORD combines more than 350 researchers (43 principal investigators <strong>and</strong> 312 trainees, technicians, <strong>and</strong> staff to foster<br />

<strong>and</strong> maintain an interdisciplinary, collaborative research <strong>and</strong> training environment.<br />

ICORD programs bring together researchers <strong>and</strong> practitioners from the basic sciences, social sciences, medicine, surgery, rehabilitation,<br />

engineering, kinesiology, education, <strong>and</strong> the humanities to facilitate the discovery, development <strong>and</strong> implementation of relevant solutions<br />

that will make a difference for people with spinal cord injury today <strong>and</strong> tomorrow.


262<br />

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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Down Syndrome<br />

Research Foundation<br />

(DSRF)<br />

http://www.dsrf.org/<br />

B.C. Mental Health <strong>and</strong><br />

Addictions Research<br />

Institute (BCMHARI)<br />

www.mhanet.ca<br />

Centre for Addictions<br />

Research of B.C.<br />

www.carbc.ca<br />

1409 Sperling Avenue<br />

Burnaby B.C. V5B 4J8<br />

Tel: 604-444-3773<br />

Toll-free in Canada at 1-888-464-<br />

DSRF<br />

Fax: 604-431-9248<br />

Contact: Naznin Virji-Babul, Director,<br />

Research<br />

naznin@dsrf.org<br />

B.C. Mental Health <strong>and</strong> Addictions<br />

Research Network<br />

PHSA Research <strong>and</strong> Networks<br />

Suite 201-601 West Broadway<br />

Vancouver B.C. V5Z 4C2<br />

info@mhanet.ca<br />

Tel: 604.707.6390<br />

Fax: 604.707.6399<br />

Contact:<br />

Jane Hood Network Director<br />

Tel: 604.707.6393<br />

University of Victoria<br />

Technology Enterprise Facility<br />

Room 273 2300 McKenzie Ave<br />

Victoria B.C. V8P 5C2<br />

Tel: 250-472-5445<br />

Fax: 250-472-5321<br />

carbc@uvic.ca<br />

Contact: Timothy Stockwell, Director<br />

timstock@uvic.ca<br />

Tel: 250-472-5445<br />

DSRF initiates <strong>and</strong> participates in research that provides insight into the unique learning style of Down’s Syndrome individuals. Data<br />

collected is analysed <strong>and</strong> pilot interventions <strong>and</strong> educational programs are developed <strong>and</strong> offered. These programs test the underst<strong>and</strong>ing<br />

of the brain <strong>and</strong> are evaluated to observe the impact on DSRF students. Even the slightest increase in cognitive ability, the objective that<br />

drives our work, can make a significant difference in the level of support an individual with an intellectual disability may require.<br />

DSRF specialises in imaging brain activity through magnetoencephalography (MEG). MEG records the magnetic fields in the brain using<br />

sensitive devices called SQUIDs (Superconducting Quantum Interference Devices). MEG installed at DSRF has a whole cortex capability<br />

BCMHARI aims to build capacity <strong>and</strong> promote networking among the diverse nodes in mental health research. In the addictions field,<br />

the Network is partnering with the Centre for Addictions Research of B.C. (CARBC), <strong>and</strong> will aim to further exp<strong>and</strong> the partnerships <strong>and</strong><br />

infrastructures that have been initiated across the province.<br />

BCMHARI Network has provided funding to develop four Research <strong>and</strong> Knowledge Transfer Hubs:<br />

• Alcohol <strong>and</strong> Drug Monitoring Hub: aims to describe the main patterns of alcohol <strong>and</strong> other drug use <strong>and</strong> related harms in B.C..<br />

• <strong>Clinical</strong> Research Hub: is designed to assist researchers in the selection <strong>and</strong> employment of measures to assess cognition, substance use,<br />

<strong>and</strong> severe psychopathology.<br />

• Community Based Research Hub: aims to increase capacity for CBR in mental health <strong>and</strong> addictions by providing access to CBR-specific<br />

training, resources, <strong>and</strong> networking opportunities.<br />

• Pharmacoepidemiology Hub: is a resource for researchers interested in using B.C.’s prescription database, PharmaNet, to study patterns of<br />

utilization of pharmacological agents in the treatment of mental illness <strong>and</strong> addiction.<br />

CARB is a provincial research network involving a partnership of SFU, Thompson Rivers University, the UBC, the UNBC <strong>and</strong> UVic, <strong>and</strong> administered<br />

by UVic. Advances public policy on substance use, harm reduction, <strong>and</strong> addiction issues in B.C. through research that sheds light on<br />

their social, cultural <strong>and</strong> psychological determinants.<br />

CARB core activities include:<br />

• To build research infrastructure <strong>and</strong> capacity across B.C. for the conduct of research that will increase underst<strong>and</strong>ing <strong>and</strong> support more<br />

effective responses to substance use<br />

• To conduct high-quality research that increases underst<strong>and</strong>ing of substance use <strong>and</strong> addiction, <strong>and</strong> informs effective responses<br />

• To disseminate research findings that increase underst<strong>and</strong>ing of substance use <strong>and</strong> addiction in order to increase awareness of related<br />

harms <strong>and</strong> to identify effective responses<br />

• To contribute to the implementation of evidence-based policy <strong>and</strong> practice.


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263<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Centre for Applied<br />

Research in Mental<br />

Health & Addiction<br />

(CARMHA)<br />

http://www.carmha.<br />

ca/<br />

SFU Faculty of Health <strong>Sciences</strong><br />

Suite 2400, 515 W. Hastings Street<br />

Vancouver B.C. V6B 5K3<br />

info@carmha.ca<br />

Benedikt Fischer<br />

Faculty <strong>and</strong> Interim Director<br />

Contact: Marilyn Sakiyama, Project<br />

Manager<br />

msakiyam@sfu.ca<br />

Tel: 778-782-5178<br />

3. CANCER SPECIFIC RESEARCH INSTITUTES<br />

B.C. Cancer Research<br />

Centre<br />

www.bccrc.ca<br />

675 West 10th Avenue<br />

Vancouver B.C. V5Z 1L3<br />

Tel: 604-675-8000<br />

Contact: Sue Smith, Executive Assistant<br />

to the Vice-President, Administration<br />

<strong>and</strong> Services<br />

Research Administration<br />

ssmith4@bccancer.bc.ca<br />

Tel: 604-675-8109<br />

Fax: 604-675-8187<br />

CARMHA m<strong>and</strong>ate is to conduct research that can be applied to enhance the effectiveness, efficiency, <strong>and</strong> quality of mental health <strong>and</strong> addiction<br />

services in B.C. <strong>and</strong> beyond. CARMHA research activities often address innovative approaches to the development, implementation<br />

<strong>and</strong> dissemination <strong>and</strong> evaluation of health promotion activities, preventive strategies <strong>and</strong> treatment services, particularly those that can<br />

be applied at a system-wide, population level.<br />

CARMHA research activities are in the areas of:<br />

• Workplace Mental Health<br />

• Self-Care<br />

• System Reform<br />

• Quality, Access & Evaluation<br />

• Population Health<br />

• Primary & Collaborative Mental Health Care<br />

• Mental Health, Addictions & the Corrections System<br />

• Knowledge Translation.<br />

BCCRC performs basic, epidemiologic, <strong>and</strong> clinical research on cancer prevention, early diagnosis of cancer, the molecular <strong>and</strong> genetic<br />

characteristics of the cancer process, <strong>and</strong> basic research related to new treatments for cancer.<br />

BCCRC is the research arm of the B.C. Cancer Agency (BCCA), <strong>and</strong> is supported by the B.C. Cancer Foundation. With direct links to the cancer<br />

centres across the province, discoveries at the BCCRC are quickly translated into clinical applications.<br />

BCCRC is home to eight research departments, <strong>and</strong> BCCA Laboratory research takes place primarily in specific centres:<br />

• B.C. Cancer Agency’s Research Centre in Vancouver<br />

• Terry Fox Laboratory in Vancouver<br />

• Michael Smith Genome <strong>Sciences</strong> Centre in Vancouver<br />

• B.C. Cancer Agency’s Deeley Research Centre, Vancouver Isl<strong>and</strong> Centre in Victoria.<br />

BCCRC Research specialities include:<br />

• Advanced Therapeutics<br />

• Cancer Control Research<br />

• Cancer Endocrinology<br />

• Cancer Genetics <strong>and</strong> Developmental Biology<br />

• Cancer Imaging<br />

• Medical Biophysics<br />

• Molecular Oncology <strong>and</strong> Breast Cancer Program<br />

• Tumour Tissue Repository<br />

• Prostate Cancer Research Program.


264<br />

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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Functional Imaging<br />

Program (FIP)<br />

BCCA<br />

www.bccrc.ca/ci/<br />

www.bccrc.ca/at/athomefunctionalimaging.html<br />

The Vancouver Prostate<br />

Centre, including<br />

the:<br />

Translational Research<br />

Initiative for Accelerated<br />

Discovery <strong>and</strong><br />

Development (PC-<br />

TRIADD)<br />

VCHRI<br />

www.prostatecentre.<br />

com<br />

www.pctriadd.com<br />

Finl<strong>and</strong>ia Natural<br />

Pharmacy<br />

www.finl<strong>and</strong>iahealth.<br />

com<br />

InspireHealth<br />

www.inspirehealth.<br />

ca/<br />

B.C. Cancer Agency - Vancouver Centre<br />

600 West 10th Avenue<br />

Vancouver B.C. V5Z 4E6<br />

Medical Director: Don Wilson<br />

dowilson@bccancer.bc.ca<br />

Tel: 604-707-5979<br />

Contact: Francois Benard, Scientific<br />

Director<br />

fbenard@bccrc.ca<br />

Tel: 604-675-8206<br />

Diamond Health Care Centre<br />

6th Floor<br />

2775 Laurel Street<br />

Vancouver, B.C. V5Z 1M9<br />

VPC Prostate Research Facility<br />

2660 Oak Street<br />

Vancouver, B.C., V6H 3Z6<br />

Tel: 604-875-4818<br />

Fax: 604-875-5654<br />

info@prostatecentre.com<br />

1111 West Broadway,<br />

Vancouver, B.C. V6H 1G1<br />

Tel: 604-733-5323<br />

Toll free: 1-800-363-4372<br />

Fax: 604-733-5340<br />

#200—1330 West 8th Avenue<br />

Vancouver, B.C. V6H 4A6<br />

Tel: 604-734-7125<br />

Fax: 604-734-7105<br />

info@inspirehealth.ca<br />

Chief Executive Officer<br />

Hal Gunn<br />

Contact: Stephanie Klaus, Development<br />

Manager<br />

FIP BCCA oversees clinical <strong>and</strong> research activities related to PET/CT imaging at the BCCA. FIP BCCA operates the only clinical PET/CT scanner<br />

in B.C., located at the Vancouver Centre. FIP BCCA also has a state-of-the art small animal PET/CT scanner housed at the B.C. Cancer<br />

Research Centre which is used for pre-clinical studies. Construction of a new 6000 sq ft cyclotron <strong>and</strong> radiopharmaceutical production <strong>and</strong><br />

research facility is underway <strong>and</strong> this will provide space for a 2nd PET/CT scanner. It will enable sustainable FDG production as a diagnostic<br />

radiopharmaceutical, providing opportunities for new radiotracer development <strong>and</strong> clinical trials.<br />

FIP BCCA Centre of Excellence for Functional Cancer Imaging is being developed to:<br />

• Improve cancer diagnosis <strong>and</strong> treatment planning for patients <strong>and</strong> health care professionals<br />

• Build research programs for the discovery, development <strong>and</strong> application of new radiotracers<br />

• Apply new advances in imaging to improve prevention, early diagnosis <strong>and</strong> management of cancers<br />

• Collaborate in a growing national <strong>and</strong> international network of functional imaging programs.<br />

The VPC research <strong>and</strong> clinical team focuses its efforts on fighting prostate cancer through improved underst<strong>and</strong>ing of prevention, diagnosis,<br />

<strong>and</strong> treatment, as well as patient education. PC–TRIADD is a translational research centre <strong>and</strong> designated Centre of Excellence for<br />

Commercialization <strong>and</strong> Research focused on improving outcomes in prostate cancer. The VPC houses a large biorepository of untreated <strong>and</strong><br />

post-treated prostate, bladder, <strong>and</strong> kidney cancers for target <strong>and</strong> biomarker characterization studies. It prides itself on its ability to move<br />

laboratory discoveries through the checks <strong>and</strong> balances of clinical trials <strong>and</strong> eventually to develop these research findings into new <strong>and</strong><br />

more effective treatments.<br />

VPC/PC-TRIADD research interests include:<br />

• Pre-clinical <strong>and</strong> clinical evaluation of novel anti-cancer inhibitors<br />

• Elucidation of mechanisms of <strong>and</strong>rogen-independent progression<br />

• Gene targeting device<br />

• Role of <strong>and</strong>rogens in promoting prostate tumor<br />

• Psycho-social aspects of prostate disease.<br />

Finl<strong>and</strong>ia has recently partnered with InspireHealth, Canada’s only government funded, research-based integrated cancer care centre.<br />

Its program strongly promotes personal engagement in health through nutrition, exercise, <strong>and</strong> emotional <strong>and</strong> spiritual support— vital<br />

components for optimal cancer care, health <strong>and</strong> healing.<br />

InspireHealth is located in Vancouver, <strong>and</strong> is Canada’s foremost integrated cancer care centre, leading the way through research <strong>and</strong> innovative<br />

cancer care programs integrated with conventional cancer treatment.<br />

InspireHealth medical doctors have helped guide more than 5,500 patients to integrate research-informed natural approaches to health<br />

into their cancer treatment <strong>and</strong> recovery. There is growing evidence that these natural approaches to supporting health <strong>and</strong> immune<br />

system function can significantly decrease the risk of cancer recurrence <strong>and</strong> increase survival.


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265<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

4. INFECTIOUS DISEASE SPECIFIC RESEARCH INSTITUTES<br />

B.C. Centre for Disease<br />

Control<br />

www.bccdc.ca<br />

B.C. Centre for Excellence<br />

in HIV/AIDS<br />

www.cfenet.ubc.ca<br />

CIHR Canadian HIV<br />

<strong>Trials</strong> Network<br />

www.hivnet.ubc.ca<br />

655 West 12th Avenue<br />

Vancouver, B.C. V5Z 4R4<br />

Tel: 604-707-2400<br />

Fax: 604-707-2401<br />

admininfo@bccdc.ca<br />

St. Paul’s Hospital Providence<br />

Healthcare<br />

608 - 1081 Burrard Street<br />

Vancouver B.C. V6Z 1Y6<br />

Director: Dr. Julio Montaner<br />

Tel: 604-806-8477<br />

Fax: 604-806-9044<br />

Contact: Marianne Harris<br />

Tel: 604-806-8771<br />

mharris@cfenet.ubc.ca<br />

620B - 1081 Burrard Street<br />

Vancouver, B.C. V6Z 1Y6<br />

Tel: 604-806-8327<br />

Fax: 604-806-8210<br />

Toll Free: 1-800-661-4664<br />

Director: Martin Schecter<br />

Contact: Aslam Anis, National Co-<br />

Director<br />

Tel: 604-806-8712<br />

aslam.anis@ubc.ca<br />

BCCDC provides provincial <strong>and</strong> national leadership in public health through surveillance, detection, treatment, prevention <strong>and</strong> consultation<br />

services. BCCDC provides both direct diagnostic <strong>and</strong> treatment services for people with diseases of public health importance <strong>and</strong><br />

analytical <strong>and</strong> policy support to all levels of government <strong>and</strong> health authorities.<br />

BCCDC investigates <strong>and</strong> evaluates the occurrence of communicable diseases in B.C. <strong>and</strong> is the provincial reporting centre for reportable<br />

cases <strong>and</strong> categories of communicable diseases. In addition, the Centre creates opportunities for scientists, health professionals, university<br />

<strong>and</strong> other partners to contribute their knowledge <strong>and</strong> experience in resolving the outst<strong>and</strong>ing health challenges facing British Columbians.<br />

BCCDC is an agency of the Provincial Health Services Authority. Scientific <strong>and</strong> technical support is provided by the following specialized divisions.<br />

These divisions supply statistics <strong>and</strong> reports in disease surveillance, <strong>and</strong> research publications in disease outcomes <strong>and</strong> treatment:<br />

• Epidemiology Services<br />

• Vaccine <strong>and</strong> Pharmacy Services<br />

• Hepatitis Division<br />

• STI/HIV Prevention <strong>and</strong> Control<br />

• Tuberculosis Control<br />

• Mathematical Modelling Unit<br />

• Public Health Emergency Management<br />

• Environmental Health Services<br />

• UBC Centre for Disease Control.<br />

Centre for Excellence HIV clinical research program focuses on further defining the role of antiretroviral therapy for the treatment of HIV<br />

infection.<br />

CFE HIV Current priorities include:<br />

• The evaluation of antiretroviral safety <strong>and</strong> efficacy of specific treatment regimens, simplified regimens, adjunctive therapies <strong>and</strong> new<br />

formulations of existing drugs.<br />

• Investigations into treatments for HIV patients co-infected with other viruses, such as hepatitis B <strong>and</strong> C.<br />

• New approaches to the treatment of HIV-related opportunistic infections; <strong>and</strong> investigations related to drug toxicities <strong>and</strong> metabolic risk<br />

factors associated with HIV.<br />

The clinical team includes individuals with expertise in all areas of HIV care with special emphasis on primary care, infectious diseases,<br />

respiratory medicine, lipid disorders, counselling <strong>and</strong> psychology, <strong>and</strong> clinical trial operations.<br />

CTN is an innovative partnership of clinical investigators, physicians, nurses, people living with HIV/AIDS, pharmaceutical manufacturers<br />

<strong>and</strong> others that facilitates HIV/AIDS clinical trials of the highest scientific <strong>and</strong> ethical st<strong>and</strong>ards.<br />

CTN provides a national <strong>and</strong> regional infrastructure to facilitate clinical trials in HIV/AIDS. CTN Core Research teams develop a clinical trial,<br />

from first concept to final protocol. CTN managers, statisticians, data methodologists, communications officers <strong>and</strong> others also assist in<br />

managing all aspects of an HIV trial.<br />

CTN Core research Teams focus on four areas of HIV research:<br />

• Antiretroviral Therapies<br />

• <strong>Clinical</strong> Management Science<br />

• Concurrent Diseases <strong>and</strong> Vulnerable Populations<br />

• Vaccines <strong>and</strong> Immunotherapies.


266<br />

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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

5. CARDIOVASCULAR SPECIFIC RESEARCH INSTITUTES<br />

Healthy Heart Centre<br />

(HHC)<br />

www.heartcentre.ca<br />

The James Hogg<br />

iCAPTURE Centre for<br />

Cardiovascular <strong>and</strong><br />

Pulmonary Research<br />

(Heart Lung Institute)<br />

www.iCapture.ubc.ca<br />

The Heart Centre<br />

St. Paul’s Hospital<br />

Rm 444 B - 1081 Burrard Street<br />

Vancouver, B.C. V6Z 1Y6<br />

Healthy Heart Program<br />

Prevention Clinic<br />

Main floor B180 - Burrard Building<br />

1081 Burrard St<br />

Vancouver, B.C. V6Z 1Y6<br />

Tel: 604-806-8591<br />

Fax: 604-806-8590<br />

St. Paul’s Hospital<br />

Rm 166 - 1081 Burrard St.<br />

Vancouver, B.C. V6Z 1Y6<br />

Tel: 604-806-8346<br />

Fax: 604-806-8351<br />

Bruce McManus, Director iCAPTURE<br />

Centre<br />

Contact: Khadija Hirji, Executive<br />

Administrator<br />

Tel: 604-806-8586<br />

Fax: 604-806-9274<br />

khirji@mrl.ubc.ca<br />

HHC undertakes clinical research studies in human volunteers to answer specific health questions <strong>and</strong> the fastest <strong>and</strong> safest way to find<br />

treatments that work in people <strong>and</strong> ways to improve health:<br />

• Interventional experimental treatments or new ways of using known therapies are safe <strong>and</strong> effective, in controlled situations: including<br />

medications, new devices or surgery, or other procedures such as counselling or lifestyle changes. Being in a study like this may last from<br />

days to years.<br />

• Observational or descriptive studies include: questionnaires, blood tests, X-rays or other tests, <strong>and</strong> they may last weeks or even years.<br />

HHC undertakes laboratory research usually on samples of human tissue, cells or molecules. The Heart Centre is closely linked with The<br />

James Hogg iCAPTURE Centre (see below).<br />

HHC partners include:<br />

• Provincial Health Services Authority (PHSA)<br />

• Providence Heart <strong>and</strong> Lung Institute<br />

• PHSA Cardiac Services<br />

• B.C. Children’s Hospital<br />

• B.C. Women’s Hospital & Health Centre<br />

• B.C. Cardiac Registries<br />

• B.C. Transplant<br />

• Vancouver General Hospital (VGH)<br />

• UBC.<br />

The James Hogg iCAPTURE Centre (Imaging, Cell Analysis, <strong>and</strong> Phenotyping Toward Underst<strong>and</strong>ing Responsive, Reparative, Remodelling,<br />

<strong>and</strong> Recombinant Events) at St. Paul’s Hospital, is a UBC Senate-approved research centre supported collaboratively by the Faculty of<br />

Medicine of UBC <strong>and</strong> Providence Health Care.<br />

iCAPTURE currently has over 250 personnel working towards solving the problems of heart, lung, <strong>and</strong> blood vessel diseases. The iCAPTURE<br />

Centre is using the best available technology to image <strong>and</strong> measure changes in molecules, cells, tissues, organs <strong>and</strong> whole organisms,<br />

including patients, in order to underst<strong>and</strong> the link between our genes <strong>and</strong> environments in causing heart, lung, <strong>and</strong> blood vessel diseases.<br />

The role of inflammation <strong>and</strong> virus infections in the initiation <strong>and</strong> progression of disease is a central current of emphasis for the 250 staff of<br />

the Centre.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

267<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

6. PULMONARY SPECIFIC RESEARCH INSTITUTES<br />

Centre for Respiratory<br />

& Critical Care<br />

Medicine<br />

VCHRI<br />

www.centreforlunghealth.ca<br />

Pacific Lung Health<br />

Centre (PLHC)<br />

www.pacificlung.com<br />

Vancouver General Hospital<br />

The Lung Centre<br />

7th Floor 2775 Laurel Street<br />

Vancouver, B.C. V5Z 1M9<br />

Tel: 604-875-4122<br />

Fax: 604-875-4695<br />

info@centreforlunghealth.ca<br />

St Paul’s Hospital<br />

8B Providence Wing<br />

1081 Burrard Street<br />

Vancouver, B.C., V6Z 1Y6<br />

Tel: 604- 806- 8818<br />

Fax: 604-806-8839<br />

info@pacificlung.com<br />

Research Office:<br />

info@pacificlung.com<br />

Tel: 604-806-9465<br />

7. AUTOIMMUNE DISEASE SPECIFIC RESEARCH INSTITUTES<br />

Arthritis Research<br />

Centre of Canada, VGH<br />

www.arthritisresearch.ca<br />

Suite 300, 895 West 10th Avenue<br />

Vancouver, B.C. V5Z 1L7<br />

Tel : 604-879-7511<br />

Fax : 604-879-3791<br />

Executive Director<br />

Contact: Shauneen Kellner<br />

Centre for Lung Health is focused on clinical care, education <strong>and</strong> research related to lung diseases. The Centre brings together researchers<br />

from the UBC campus <strong>and</strong> its affiliated academic teaching hospitals as well the BCCA <strong>and</strong> the B.C. Centre for Disease Control, UVic<br />

<strong>and</strong>SFU.<br />

CLH research to improve prevention, diagnosis, <strong>and</strong> treatment of respiratory <strong>and</strong> critical care illnesses including lung cancer, asthma,<br />

chronic obstructive pulmonary disorder, sleep apnoea, <strong>and</strong> Tuberculosis. <strong>Clinical</strong> <strong>Trials</strong> at the Lung Centre are active in pulmonary research<br />

<strong>and</strong> on-going clinical drug trials.<br />

CLH Lung Centre specializes in the treatment of pulmonary conditions such as asthma, emphysema, chronic bronchitis, bronchiectasis,<br />

lung cancer, occupational <strong>and</strong> environmental lung diseases, sarcoidosis, pneumonia, tuberculosis, pulmonary hypertension <strong>and</strong> interstitial<br />

lung disease.<br />

PLHC is an academic clinical program dedicated to the care for patients with lung disease. The Pacific Lung Research Centre is part of<br />

the PLHC; it is currently conducting studies in various respiratory disease areas, including chronic obstructive pulmonary disease (bronchitis<br />

<strong>and</strong> emphysema), interstitial pulmonary fibrosis, chronic cough, cystic fibrosis, <strong>and</strong> asthma.<br />

Arthritis Research Centre of Canada (ARC) conducts consumer-driven clinical research <strong>and</strong> trials related to arthritis diagnosis, prognosis,<br />

prevention, care outcomes <strong>and</strong> quality of life issues.<br />

ARC is a patient-oriented research centre, with a wide range of disciplines including rheumatology, rehabilitation science, public health,<br />

epidemiology, biostatistics, health psychology, health economics <strong>and</strong> education.<br />

ARC work is supported through relationships <strong>and</strong> partnerships with universities, hospitals, funding agencies, arthritis treatment centres,<br />

<strong>and</strong> both the B.C. <strong>and</strong> Yukon Division <strong>and</strong> the National Office of The Arthritis Society.<br />

ARC scientists are committed to practical research for everyday living, to reduce the burden of arthritis, <strong>and</strong> giving people with arthritis<br />

better, more timely, <strong>and</strong> cost-effective solutions for living with their disease.


268<br />

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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Immunity & Infection<br />

Research Centre (IIRC)<br />

VCHRI<br />

www.iirc.ca/Immunity_<strong>and</strong>_Infection_Research_Centre.htm<br />

Prevention of Organ<br />

Failure Centre of Excellence<br />

(PROOF)<br />

www.proof.hli.ubc.ca<br />

IIRC labs are at:<br />

• Heather Pavilion East,<br />

2733 Heather Street V5Z 3J5<br />

• Jack Bell Research Centre, 2660 Oak<br />

Street B.C. V6H 3Z6<br />

• Research Pavilion, 828 West 10th<br />

Avenue V6Z 1L8<br />

• B.C. Centre for Disease Control, 655<br />

West 12th Avenue V5Z 4R4<br />

Contact: Jeffrey Helm, Research<br />

Co-ordinator<br />

604-875-4111 x 68576<br />

jhelm@interchange.ubc.ca<br />

Room 166, Burrard Building, 1081<br />

Burrard Street, Vancouver B.C. V6Z<br />

1Y6<br />

Tel: 604-806-8328<br />

Fax: 604-806-9274<br />

proof@hli.ubc.ca<br />

Contact: Marjorie Co, Chief Development<br />

Officer<br />

Tel: 604-806-8934<br />

Marjorie.Co@hli.ubc.ca<br />

8. OTHER DISEASE-BASED HEALTH RESEARCH CENTRES<br />

B.C. Provincial Renal<br />

Agency (BCPRA)<br />

www.bcrenalagency.<br />

ca/default.htm<br />

B.C. Provincial Renal Agency<br />

St Paul’s Hospital<br />

700-1380 Burrard Street<br />

Vancouver B.C. V6Z 2H3<br />

Tel: 604-875-7340<br />

Contact: Adeera Levin<br />

bcpra@bcpra.ca<br />

A collaborative team of basic scientists, clinicians, <strong>and</strong> health professionals whose expertise spans genomics, molecular microbiology,<br />

immunology, infectious diseases, transplantation immunology, medical genetics, epidemiology, health care delivery, <strong>and</strong> policy development.<br />

IIRC research interests include basic mechanisms of human immune responses involved in transplantation <strong>and</strong> infectious diseases in order<br />

to improve public health outcomes <strong>and</strong> health services. Current programs Include:<br />

• Transplant immunology<br />

• PREPARE - proteomics approaches to rapidly identify novel targets in microbial pathogens leading to novel therapeutics <strong>and</strong> vaccines for<br />

emerging infectious diseases.<br />

• Centre for Human Islet Transplant <strong>and</strong> Beta Cell Regeneration: transplantation of beta-cells is a promising treatment option that eliminates<br />

the need for insulin injections. CHITBCR conducts research to address the main limitations of beta-cell transplant.<br />

The PROOF Centre discovers, develops, commercializes <strong>and</strong> implements non-invasive tests (biomarkers) for prevention, diagnosis, prediction,<br />

management, <strong>and</strong> treatment of diseases associated with organ failure.<br />

It carries forward programs in the development of biomarkers for heart, lung, <strong>and</strong> kidney failure as well as for new blood assays for genes,<br />

proteins, <strong>and</strong> metabolites. One of the PROOF Centre’s flagship programs is the “Biomarkers in Transplantation” initiative. Now in its second<br />

phase, this innovative project has identified biomarkers in the blood that will tell the clinical transplant team immediately whether a<br />

transplanted organ is being rejected, using a simple blood test.<br />

BCPRA plans <strong>and</strong> monitors the delivery of province-wide kidney care services.<br />

BCPRA addresses the challenge of kidney disease by:<br />

• improving early diagnosis <strong>and</strong> treatment<br />

• ensuring that the system itself is financially sustainable<br />

• educating British Columbians about the risks <strong>and</strong> signs of kidney disease<br />

BCPRA activities include:<br />

• Plans <strong>and</strong> monitors the delivery of province-wide kidney care services<br />

• Develops province-wide clinical st<strong>and</strong>ards <strong>and</strong> guidelines<br />

• Develops funding models to support best health outcomes<br />

• Measures <strong>and</strong> reports on patient <strong>and</strong> system outcomes<br />

• Supports knowledge-development through research <strong>and</strong> teaching.


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269<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Centre for Hip Health<br />

& Mobility (CHHM),<br />

VCHRI<br />

www.hiphealth.ca<br />

The Department of<br />

Dermatology <strong>and</strong> Skin<br />

Science (DDSC)<br />

http://www.derm.ubc.<br />

ca/about_ubc_dermatology/default.htm<br />

3/F 2647 Willow Street<br />

Willow Chest Centre<br />

Vancouver, B.C. V5Z 1M9<br />

Tel: 604-875-5250<br />

Fax: 604-875-4762<br />

chhcontactus@hiphealth.ca<br />

DDSC<br />

835 West 10th Avenue<br />

Vancouver, B.C. V5Z 4E8<br />

Tel: 604-875-4747<br />

Fax: 604-873-9919<br />

Department Head: Harvey Lui<br />

Research Directors: Jan Dutz, Gang Li<br />

Contact: Karen Ng, Administrator<br />

Tel: 604-875-4111 x 61324<br />

karen.ng@ubc.ca<br />

9. CHILD AND YOUTH HEALTH RESEARCH CENTRES<br />

Child <strong>and</strong> Family<br />

Health Research Institute<br />

(CFRI)<br />

www.cfri.ca<br />

950 West 28th Avenue<br />

Vancouver, B.C. V5Z 4H4<br />

Tel: 604-875-3194<br />

Fax: 604-875-3076<br />

MacLeod, Stuart: Executive Director<br />

Tel: 604-875-2404<br />

smacleod@cw.bc.ca<br />

CHHM aims to prevent falls <strong>and</strong> hip fractures through early intervention with programs for youths <strong>and</strong> seniors, educate <strong>and</strong> train skilled<br />

scientists <strong>and</strong> clinicians, detect osteoarthritis at an early stage, treat bone <strong>and</strong> joint problems with more effective surgical solutions, including<br />

minimally invasive surgeries, evaluate the impact, effectiveness <strong>and</strong> costs of novel interventions, translate research that is relevant,<br />

effective <strong>and</strong> sustainable into programs, practices <strong>and</strong> policies through knowledge integration.<br />

CHHM brings together researchers from a wide range of disciplines to investigate <strong>and</strong> treat hip fractures <strong>and</strong> osteoarthritis, <strong>and</strong> create<br />

new surgical solutions<br />

CHHM integrated research program focuses on four key areas:<br />

• Hip Fracture Prevention.<br />

• Early Detection of Hip Osteoarthritis<br />

• Surgical Solutions<br />

• Knowledge Translation<br />

DDSC trains undergraduate medical students to have a grounding <strong>and</strong> basic training in Dermatology through the Undergraduate Program,<br />

while graduate medical students are trained to become fully licensed Dermatologists in our Postgraduate Program for residents.<br />

DDSC Research involves research through the <strong>Clinical</strong> <strong>Trials</strong> Unit <strong>and</strong> our five specialized laboratories:<br />

• Skin Cancer Biology Laboratory<br />

• Photomedicine <strong>and</strong> Optics Laboratory<br />

• Hair Research Laboratory<br />

• Immunodermatology Laboratory<br />

• Laboratory of Predictive Medicine <strong>and</strong> Therapeutics<br />

By analyzing the needs of the community, DDSC design research projects to address those needs. The output of DDSC research is new<br />

knowledge, new drugs, new techniques, new patents, <strong>and</strong> more – DDSC take this information back to our clinical settings to help <strong>and</strong><br />

treat out patients.<br />

CFHRI is the largest child <strong>and</strong> family-related research institute in Western Canada <strong>and</strong> works in close partnership with B.C. Children’s<br />

Hospital <strong>and</strong> Sunny Hill Health Centre for Children, B.C. Women’s Hospital & Health Centre, agencies of the Provincial Health Services<br />

Authority; B.C. Children’s Hospital Foundation; <strong>and</strong> UBC. Research spans a wide range of children’s <strong>and</strong> women’s health concerns. Main<br />

areas of research are:<br />

• Childhood Cancer<br />

• Diabetes, Nutrition & Metabolism<br />

• Developmental Neurosciences & Child Health<br />

• Genetics & Health<br />

• Immunity in Health & Disease<br />

• Innovations in Acute Care & Technology<br />

• Reproduction & Healthy Pregnancy.


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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Children’s Health<br />

Policy Centre (CHPC)<br />

www.childhealthpolicy.sfu.ca<br />

Department of Pediatrics<br />

(DOP)<br />

UBC<br />

www.pediatrics.med.<br />

ubc.ca<br />

Faculty of Health <strong>Sciences</strong>, Simon<br />

Fraser University<br />

Room 2435, 515 West Hastings Street<br />

Vancouver, B.C.<br />

V6B 5K3<br />

CHPC Director: Charlotte Waddell<br />

Tel: 778-782-7769<br />

charlotte_waddell@sfu.ca<br />

Contact: Brigitte Bennetsen, Office<br />

Manager<br />

Tel: 778-782-7775<br />

Fax: 778-782-7777<br />

chpc@sfu.ca<br />

UBC Faculty of Medicine<br />

Room 2D19, 4480 Oak Street<br />

B.C. Children’s Hospital<br />

Vancouver, B.C. V6H 3V4<br />

Tel: 604-875-3177<br />

Fax: 604-875-2890<br />

Department Head: Robert Armstrong<br />

Contact: Marcelle Sprecher, Acting<br />

Director of Administration<br />

msprecher@cw.bc.ca<br />

CHPC is an interdisciplinary research group in the Faculty of Health <strong>Sciences</strong> at Simon Fraser University. CHPC focus is on integrating<br />

research <strong>and</strong> policy to improve children’s social <strong>and</strong> emotional well-being or children’s mental health. CHPC work complements the mission<br />

of the Faculty of Health <strong>Sciences</strong> to integrate research <strong>and</strong> policy for population <strong>and</strong> public health locally, nationally <strong>and</strong> globally.<br />

CHPC have prepared systematic reviews of the best available research evidence on the prevention <strong>and</strong> treatment of children’s mental<br />

disorders.<br />

• Treating Concurrent Substance Use <strong>and</strong> Mental Disorders in Children <strong>and</strong> Youth<br />

• Preventing Substance Use Disorders in Children <strong>and</strong> Youth<br />

• Preventing <strong>and</strong> Treating Childhood Sexual Abuse<br />

• Mental Health <strong>and</strong> Developmental Disabilities in Children<br />

• Implementing Evidence-Based Practice in Children’s Mental Health<br />

• Preventing <strong>and</strong> Treating Obsessive-Compulsive Disorder in Children <strong>and</strong> Youth<br />

• Preventing <strong>and</strong> Treating Eating Disorders in Children <strong>and</strong> Youth<br />

• Preventing Suicide in Youth: Taking Action With Imperfect Knowledge<br />

• The Mental Health <strong>and</strong> Well-Being of Aboriginal Children <strong>and</strong> Youth: Guidance for New Approaches <strong>and</strong> Services<br />

• Preventing <strong>and</strong> Treating Depression in Children <strong>and</strong> Youth<br />

• Early Psychosis: A Review of the Treatment Literature<br />

• Preventing <strong>and</strong> Treating Anxiety Disorders in Children <strong>and</strong> Youth<br />

• Preventing <strong>and</strong> Treating Conduct Disorder in Children <strong>and</strong> Youth<br />

• Child <strong>and</strong> Youth Mental Health Research Reports: Prevalence of Mental Disorders in Children <strong>and</strong> Youth<br />

• Child <strong>and</strong> Youth Mental Health Research Reports: Draft Practice Parameters<br />

• Child <strong>and</strong> Youth Mental Health Research Reports: Population Health <strong>and</strong> <strong>Clinical</strong> Service Considerations.<br />

DOP of UBC <strong>and</strong> B.C.’s Children’s Hospital consists of physicians, scientists, allied health professionals <strong>and</strong> administrative staff trained in<br />

pediatric <strong>and</strong> allied child health disciplines. DOP m<strong>and</strong>ate is to provide leadership <strong>and</strong> excellence in the following areas: Patient Care,<br />

Education, Research <strong>and</strong> Child Advocacy.<br />

DOP continues to work towards being a cohesive academic <strong>and</strong> professional body committed to the advancement of betterment of child<br />

health care through the delivery of exemplary patient care, teaching <strong>and</strong> research. DOP core facilities support development of a broad<br />

range of basic <strong>and</strong> clinical research initiatives. Infection <strong>and</strong> immunity is a particular strength with an outst<strong>and</strong>ing research program that<br />

spans transplantation to immunization.<br />

DOP Paediatric Oncology Research Program is an area of strength with major donor commitments. Underst<strong>and</strong>ing influences on early<br />

development <strong>and</strong> the interface between biology, behaviour <strong>and</strong> the environment is an area of strength. Epigenetics is a developing major<br />

area of research that is shared by numerous divisions.<br />

DOP <strong>Clinical</strong> Research Support Unit (CRSU) supports academic research in the domains of clinical, health services <strong>and</strong> population<br />

health <strong>and</strong> works with the divisions to improve the organization <strong>and</strong> delivery of quality health care <strong>and</strong> to promote patients’ safety. DOP<br />

leads a national network aimed at identifying the genomic profile of patients who develop serious drug related events.


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271<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

The McCreary Centre<br />

Society (MCS)<br />

www.mcs.bc.ca<br />

3552 Hastings Street E.<br />

Vancouver, B.C. V5K 2A7<br />

Tel: 604-291-1996<br />

Fax: 604-291-7308<br />

mccreary@mcs.bc.ca<br />

Executive Director: Annie Smith<br />

Contact: Elizabeth Saewyc, Research<br />

Director<br />

10. WOMEN’S HEALTH RESEARCH CENTRES<br />

B.C. Centre of Excellence<br />

for Women’s<br />

Health (BCCEWH)<br />

www.bccewh.bc.ca<br />

Centre for Menstrual<br />

Cycle <strong>and</strong> Ovulation<br />

Research (CeMCOR)<br />

www.cemcor.ubc.ca<br />

E311 – 4500 Oak Street, Box 48<br />

Vancouver, B.C. V6H 3N1<br />

Tel: 604-875-2633<br />

Toll free: 1-888-300-3088 ext. 2633<br />

Fax: 604-875-3716<br />

bccewh@cw.bc.ca<br />

Contact: Ginny Gonneau<br />

Research Co-ordinator<br />

ggonneau@cw.bc.ca<br />

The Gordon <strong>and</strong> Leslie Diamond<br />

Health Care Centre<br />

Room 4111 - 4th Floor<br />

2775 Laurel Street,<br />

Vancouver B.C. V5Z 1M9<br />

Tel: 604–875-5927<br />

Fax: 604-875-5915<br />

cemcor@interchange.ubc.ca<br />

Jerilynn C. Prior, Scientific Director<br />

MCS is a small non-profit organization concerned with the health of young people in B.C.. MCS has conducted community-based research<br />

<strong>and</strong> projects addressing current youth health issues. The society takes its name from the late Dr. J.F. McCreary, a paediatrician <strong>and</strong> medical<br />

administrator, whose leadership in promoting inter-professional teaching <strong>and</strong> multi-disciplinary approaches in health care set a st<strong>and</strong>ard<br />

that the society seeks to emulate.<br />

MCS has a number of partnerships to develop research <strong>and</strong> networking opportunities, including:<br />

• Student Research Group<br />

• Sexual Orientation, Risk <strong>and</strong> Resilience Study<br />

• Experiences of Stigma <strong>and</strong> Risk Behaviours Study<br />

MCS research is in early adolescence, youth homelessness <strong>and</strong> youth vulnerability:<br />

• Promoting Resiliency in Early Adolescence<br />

• Healthy Youth Development: The Opportunity of Early Adolescence<br />

• National Training Initiative in Adolescent Health (NTIAH)<br />

• Violence in Adolescence: injury, suicide, <strong>and</strong> criminal violence in the lives of B.C. youth<br />

• Accenting the Positive: a developmental framework for reducing risk <strong>and</strong> promoting positive outcomes among B.C. youth.<br />

BCCEWH research has been framed by three themes: Healthy Women <strong>and</strong> Healthy Communities, Health Status <strong>and</strong> Health Determinants,<br />

Women Centred Care.<br />

BCCEWH current activities focus on women <strong>and</strong> addictions; mental health; health services; mothering <strong>and</strong> maternity; <strong>and</strong> physical activity.<br />

BCCEWH collaborates with women’s health researchers across B.C., across Canada <strong>and</strong> around the world. The BCCEWH is known internationally<br />

for its work on women tobacco issues, as well as change-oriented research <strong>and</strong> knowledge exchange activities.<br />

CeMCOR is an accessible research centre with a m<strong>and</strong>ate to distribute information directly to women about changes through the life cycle,<br />

from adolescence to menopause. CeMCOR’S goal is to do good science that honours the voices <strong>and</strong> experiences of women. It is the only<br />

centre in North America that focuses on ovulation <strong>and</strong> the causes for <strong>and</strong> consequences of ovulation disturbances.<br />

CeMCOR studies the physical <strong>and</strong> psychological causes <strong>and</strong> effects of ovulation disturbances on women’s overall health. CeMCOR publishes<br />

scientific results <strong>and</strong> disseminates information directly to women. CeMCOR document variations in the menstrual cycle <strong>and</strong> ovulation in<br />

the context of the lives of women of all ages. CeMCOR is analyzing the relationships of the menstrual cycle <strong>and</strong> ovulation changes with<br />

weight changes, metabolism changes, eating attitudes, breast maturation, bone physiology, pre-menstrual experiences <strong>and</strong> changes in<br />

the physiology of exercise, respiration, cardiovascular function <strong>and</strong> breast density <strong>and</strong> nodularity.


272<br />

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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Women’s Health<br />

Research Institute<br />

(WHRI)<br />

www.whri.org<br />

Room B325B - 4500 Oak Street, Box<br />

42, Vancouver B.C. V6H 3N1<br />

Tel: 604-875-3459<br />

Fax: 604-875-3895<br />

Contact: Katherine Heath<br />

Manager, Research Development<br />

Tel: 604 875-2424 x 4877<br />

kheath@cw.bc.ca<br />

WHRI is devoted solely to improving the health <strong>and</strong> health care of girls <strong>and</strong> women, to serve as a catalyst for research in women’s health<br />

<strong>and</strong> to support an exp<strong>and</strong>ing national network of women’s health researchers, policy makers <strong>and</strong> healthcare providers.<br />

WHRI current research focus includes:<br />

• HPV Vaccine Study (4-Valent vs. 9-Valent)<br />

• Genetics <strong>and</strong> Mental Illness Studies<br />

• Mother-Infant Wellness Lab<br />

• The KD-BEAR Project<br />

• Study on Osteoporosis & Urinary Incontinence<br />

• Guide for New Antepartum/Postpartum Studies<br />

WHRI research interests in fields of:<br />

• Group B Streptococcal (GBS)<br />

• Cervical Cancer<br />

• Endometriosis<br />

• Genital Herpes<br />

• Hepatitis C<br />

• Human Immunodeficiency Virus (HIV)<br />

• Human Vaginal Microbiota<br />

• NEXUS: Network of Experimental Urogynecologic Surgeons<br />

• Perinatal Anxiety Screening Study<br />

• Postpartum Mental Illness<br />

• Sexual Health & Risk Reducing Gynaecological Surgery.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

273<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

The Women’s Health<br />

Research Network<br />

(WHRN)<br />

www.whrn.ca<br />

Simon Fraser University<br />

Harbour Centre Campus<br />

Room 3277, 515 West Hastings Street,<br />

Vancouver B.C. V6B 5K3<br />

Tel: 778-782-8589<br />

Fax: 778-782-5288<br />

Contact: Susan Dixon, Provincial<br />

Networking Co-ordinator<br />

sdixon@whrn.ca<br />

WHRN is a catalyst for bringing together innovative groupings of gender <strong>and</strong> women’s health researchers <strong>and</strong> research collaborations<br />

drawn from academic, health service, policy <strong>and</strong> community settings.<br />

WHRN fosters the generation, application <strong>and</strong> mainstreaming of new knowledge <strong>and</strong> is specifically dedicated to women’s health research<br />

that will increase the underst<strong>and</strong>ing of <strong>and</strong> capacity for sex <strong>and</strong> gender-based analyses <strong>and</strong> for integrating women’s health concerns into<br />

other areas of health research.<br />

WHRN works to stimulate <strong>and</strong> support distributed nodes of activity at key B.C. institutions to achieve broad research/e-research development<br />

<strong>and</strong> knowledge translation goals. These research clusters are cross-institutional <strong>and</strong> interdisciplinary in membership <strong>and</strong> focus, <strong>and</strong><br />

designed to become intersectoral <strong>and</strong> international in scope.<br />

WHRN nodes of activity are supported by centralized co-ordination <strong>and</strong> facilitation for the purposes of network development <strong>and</strong> technical<br />

support. The following types of networking support are ongoing:<br />

• face-to-face meetings with researchers <strong>and</strong> collaborators from across the province<br />

• regular topic-oriented virtual sessions aimed at enabling knowledge exchange <strong>and</strong> research involvement<br />

• provincial <strong>and</strong> regional face-to-face <strong>and</strong>/or virtual sessions in support of the work of the four research clusters<br />

• work with the MSFHR on the further development of a database of health researchers with an interest in women’s health<br />

• work with other networks on sex <strong>and</strong> gender mainstreaming opportunities<br />

• development of the WHRN website<br />

WHRN Researchers <strong>and</strong> collaborators involved with the research clusters, advisory committees <strong>and</strong> communities of practice currently<br />

working in several distinct areas relating to women’s health research. The WHRN is also interested in supporting new research efforts <strong>and</strong><br />

collaboration from across the province. Through video-conference workshops <strong>and</strong> the use of other new technologies, researchers throughout<br />

B.C. have the opportunity to share ideas <strong>and</strong> build new opportunities for collaboration.


274<br />

BRITISH COLUMBIA<br />

APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

11. AGEING AND GERONTOLOGY RESEARCH CENTRES<br />

Centre on Ageing (COA)<br />

www.coag.uvic.ca<br />

Centre for Healthy<br />

Ageing at Providence<br />

(CHAP)<br />

www.centreforhealthyaging.ca<br />

University of Victoria<br />

PO BOX 1700, STN CSC<br />

Victoria, B.C. V8W 2Y2<br />

Tel: 250-721-6369<br />

Fax: 250-721-6499<br />

senage@uvic.ca<br />

Director<br />

Holly Tuokko<br />

Tel: 250-721-6576<br />

htuokko@uvic.ca<br />

Contact: Tom Ackerley, Manager,<br />

Survey Research Centre<br />

Tel: 250 472-5250<br />

ackerley@uvic.ca<br />

4865 Heather Street<br />

Vancouver, B.C. V5Z 0B3<br />

Tel: 604-876-7112<br />

Fax: 604-876-7113<br />

chap@providencehealth.bc.ca<br />

Contact: Sherin Rahim-Jamal srahimjamal@providencehealth.bc.ca<br />

Tel: 604-876-7112 x 600<br />

COA at the University of Victoria is a multidisciplinary research centre established in 1992. Our m<strong>and</strong>ate is to promote <strong>and</strong> conduct basic<br />

<strong>and</strong> applied research throughout the lifespan.<br />

COA research is conducted in partnership with seniors, their families, organizations, health care providers, <strong>and</strong> the government. The<br />

research conducted includes needs assessments <strong>and</strong> social surveys, experimental research, program evaluations, development of clinical<br />

diagnostic tools, <strong>and</strong> social policy research; some of which is conducted using the Survey Research Centre. COA Research areas include:<br />

• Ageing in Rural <strong>and</strong> Small-Town Environments<br />

• Caregivers/Caregiving <strong>and</strong> Social Support<br />

• Chronic Illness/Disease/Disability<br />

• Cross Cultural Studies in Aging<br />

• Driving<br />

• Environmental Health<br />

• Ethical Issues in Gerontology<br />

• Ethnicity <strong>and</strong> Immigration<br />

• Falls <strong>and</strong> Injuries Among Seniors<br />

• Gender <strong>and</strong> Sexual Diversity<br />

• Home Care/Long Term Care<br />

• Health Care Reform<br />

• Health Education<br />

• Healthy Living/Health Promotion/Self-Care<br />

• Health Service Utilization<br />

• Housing<br />

• Intellectual Disability<br />

• Intergenerational Relationships<br />

• Measurement <strong>and</strong> Psychometrics<br />

• Mental Health <strong>and</strong> Cognitive Functioning<br />

• Palliative Care/End of <strong>Life</strong><br />

• Well-being/Quality of <strong>Life</strong>.<br />

CHAP is a catalyst for improving the lives of older British Columbians. Based within a health care setting, CHAP identifies complex <strong>and</strong> long<br />

st<strong>and</strong>ing problems in the delivery of care to older British Columbians <strong>and</strong> undertakes research to illuminate poorly understood areas of<br />

elder care.<br />

CHAP is a vehicle for developing <strong>and</strong> fostering collaborative working relationships between hospitals, universities, community service<br />

providers <strong>and</strong> groups representing elders who share an interest <strong>and</strong> expertise in the health care needs of older adults. These partnerships<br />

blend complementary skills <strong>and</strong> inspire a shared vision among different organizations.<br />

CHAP also makes transferring knowledge to stakeholders a priority <strong>and</strong> engages in evidence-based advocacy to improve care delivery.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

275<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Centre for Research on<br />

Personhood in Dementia<br />

(CRPD)<br />

www.crpd.ubc.ca<br />

Gerontology Research<br />

Centre (GRC)<br />

www.sfu.ca/grc/<br />

Jack Bell Building, UBC<br />

2080 West Mall<br />

Vancouver, B.C. V6T 1Z2<br />

Tel: 604-822-6872<br />

Fax: 604-822-8656<br />

crpd@interchange.ubc.ca<br />

Director CRPD : Deborah O’Connor<br />

Tel: 604-822-5299<br />

deborah.oconnor@ubc.ca<br />

Contact: Val Ball, Research Co-ordinator,<br />

CRPD<br />

Tel: 604-822-6872<br />

crpd@interchange.ubc.ca<br />

Simon Fraser University Vancouver<br />

2800 - 515 West Hastings Street<br />

Vancouver, B.C. V6B 5K3<br />

Tel: 778-782-5062<br />

Fax: 778-782-5066<br />

gero@sfu.ca<br />

Chair, Department of Gerontology<br />

Andrew Wister<br />

wister@sfu.ca<br />

Contact: Anne Marie Barrett<br />

Manager, Academic <strong>and</strong> Administrative<br />

Services<br />

geradmin@sfu.ca<br />

CRPD is an interdisciplinary research centre committed to addressing issues related to a personhood approach to dementia <strong>and</strong> dementia<br />

care. CRPD evolved in response to a recognized need for research to examine the potential of a personhood approach to dementia<br />

care practices in B.C.. CRPD is a trans-disciplinary research centre situated in the School of Social Work <strong>and</strong> Family Studies at UBC. CRPD<br />

represents the collaboration between twelve British Columbian researchers engaged in research focused on a person-centred approach to<br />

dementia.<br />

CRPD expertise that capture biomedical, social sciences, <strong>and</strong> humanities perspectives at both academic <strong>and</strong> clinical levels, the CRPD<br />

provides a unique environment for research collaboration. Research activities are contributing to the growing body of research focused on<br />

personhood in dementia. CRPD aims to:<br />

• increase underst<strong>and</strong>ing of personhood in dementia develop interventions for supporting personhood.<br />

GRC was established in 1982 with the help of grants from Imperial Oil, the Real Estate Foundation of B.C., Shoppers Drug Mart, <strong>and</strong> the<br />

Social <strong>Sciences</strong> <strong>and</strong> Humanities Research Council of Canada. The associated Department of Gerontology was established in 1983.<br />

GRC <strong>and</strong> Department serve as a focal point for research, education <strong>and</strong> information on individual <strong>and</strong> population aging <strong>and</strong> maintain an<br />

active publications program to promote utilization of existing knowledge in the following areas:<br />

• Aging <strong>and</strong> the Built Environment<br />

• Changing Demography <strong>and</strong> <strong>Life</strong>styles<br />

• Culture <strong>and</strong> Aging<br />

• Research <strong>and</strong> development of programs to promote health, well-being <strong>and</strong> a sense of community among ethnic groups.<br />

• Health Promotion/Population Health <strong>and</strong> Aging<br />

• Prevention of Victimisation <strong>and</strong> Exploitation of Older Persons<br />

• Technology <strong>and</strong> Aging.


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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

12. RURAL AND ABORIGINAL HEALTH RESEARCH CENTRES<br />

Centre for Aboriginal<br />

Health Research<br />

(CAHR)<br />

www.cahr.uvic.ca<br />

New Emerging Team<br />

for Health in Rural<br />

& Northern British<br />

Columbia<br />

No URL<br />

University of Victoria<br />

P.O. Box 1700, STN CSC<br />

Victoria, B.C. V8W 2Y2<br />

Tel: 250-853-3115<br />

Fax: 250-472-5450<br />

dinarak@uvic.ca<br />

CAHR Director: Jeffrey Reading<br />

jreading@uvic.ca<br />

Tel: 250-472-5451<br />

Fax: 250-472-545<br />

Contact: Chris Lalonde, Associate<br />

Director<br />

Tel: 250-721-7535<br />

lalonde@uvic.ca<br />

NETHRN-BC<br />

Department of Geography<br />

PO Box 3060<br />

University of Victoria<br />

Victoria, B.C. V8W 3R4<br />

Study Director: Aleck Ostry, Canada<br />

Research Chair<br />

Contact: Analisa Blake, Research<br />

Project Manager<br />

blakea@uvic.ca<br />

CAHR is dedicated to promoting <strong>and</strong> engaging in health research in partnership with Aboriginal peoples to improve their health. The<br />

Centre is a University of Victoria research centre that was created in May 2008, <strong>and</strong> acknowledge with respect the Coast Salish <strong>and</strong> Straits<br />

Salish peoples on whose traditional territories the Centre is graciously hosted.<br />

CAHR is leading Aboriginal population health research, collaborating with the University of Victoria <strong>and</strong> the University of Northern B.C. on<br />

Network Environments for Aboriginal Research B.C. (NEARBC), funded by Michael Smith Foundation for Health Research.<br />

CAHR Research projects conducted by the UVic Aboriginal Health Research Group (AHRG) <strong>and</strong> the CAHR have been in diverse areas of Aboriginal<br />

health including: chronic disease, disability, First Nations health, knowledge translation, epidemiology, global indigenous health,<br />

participatory <strong>and</strong> collaborative community-based research, <strong>and</strong> health disparities.<br />

CAHR Research projects include:<br />

• Health <strong>and</strong> mentorship survey of indigenous youth participants at the Cowichan 2008 north American indigenous games<br />

• Health practitioners’ perspective on the barriers to diagnosis <strong>and</strong> treatment of diabetes in aboriginal people on Vancouver isl<strong>and</strong><br />

• First nations holistic policy <strong>and</strong> planning model<br />

• First nations regional longitudinal health survey.<br />

NETHRN-BC is the acronym for the New Emerging Team for Health in Rural & Northern B.C.. NETHRN-BC aims to develop <strong>and</strong> enhance<br />

research capacity in the social determinants of rural <strong>and</strong> northern health.<br />

NETHRN-BC program is to develop research capacity in the social determinants of rural <strong>and</strong> northern health in B.C.. This program is<br />

multidisciplinary <strong>and</strong> guided by leading investigators including epidemiologists, geographers, psychologists, sociologists, <strong>and</strong> statisticians.<br />

The program is based at four B.C. universities (University of Victoria, University of Northern B.C., Thompson Rivers University, <strong>and</strong> UBC).<br />

NETHRN-BC researchers are connected to communities <strong>and</strong> local <strong>and</strong> regional policy makers concerned about improving the health status<br />

of rural <strong>and</strong> northern British Columbians.<br />

NETHRN-BC projects are focused on:<br />

• development of rural health services in the Northern Health Authority<br />

• early childhood education in the interior Health Authority<br />

• exploration of rural/urban differences in health among a cohort of B.C. sawmill workers residing <strong>and</strong> working in both urban <strong>and</strong> rural<br />

communities throughout the province<br />

• exploring the empirical <strong>and</strong> theoretical dimensions of social capital <strong>and</strong> its link to health in rural communities in B.C..


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277<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

13. OTHER HEALTH RESEARCH CENTRES<br />

Centre for Blood<br />

Research (CBR)<br />

www.cbr.ubc.ca<br />

Centre for Molecular<br />

Medicine <strong>and</strong> Therapeutics<br />

www.cmmt.ubc.ca<br />

Centre for Translational<br />

<strong>and</strong> Applied<br />

Genomics (CTAG)<br />

PHSA<br />

www.phsa.ca/AgenciesAndServices/<br />

Services/PHSA-Labs/<br />

About-PHSA-Labs/<br />

CTAG.htm<br />

4th Floor, <strong>Life</strong> <strong>Sciences</strong> Centre<br />

2350 Health <strong>Sciences</strong> Mall<br />

Vancouver, B.C. V6T 1Z3<br />

Director: Ed Conway<br />

Tel: 604-822-4252<br />

Fax: 604-822-7742<br />

director@cbr.ubc.ca<br />

950 West 28th Avenue<br />

Vancouver, B.C. V5Z 4H4<br />

Tel: 604-875-3800<br />

Fax: 604-875-3819<br />

info@cmmt.ubc.ca<br />

Contact: Nicki Kahnamoui, Director of<br />

Business Development<br />

Tel: 604-875-2345 x 4832<br />

nicki@cmmt.ubc.ca<br />

3rd floor, 600 West 10th Avenue<br />

Vancouver B.C., V5Z 4E6<br />

Tel: 604-877-6000 x 2301<br />

Medical Director: Dr. David Huntsman<br />

dhuntsma@bccancer.bc.ca<br />

Business Manager: Alicja Parker<br />

aparker@bccancer.bc.ca<br />

Centre for Blood Research (CBR) was established in 2002 <strong>and</strong> is currently the largest inter-disciplinary blood research centre in the<br />

world. Current membership involves 42 investigators from the Faculties of Applied Science, Arts, Dentistry, Medicine, Pharmaceutical <strong>Sciences</strong><br />

<strong>and</strong> Science, <strong>and</strong> some with appointments at the University of Victoria <strong>and</strong> the University of Northern B.C..<br />

CBR provides leading edge biomedical research, training, education, <strong>and</strong> innovative technologies for accelerated delivery of affordable,<br />

safe, high-quality diagnostics, therapeutics <strong>and</strong> medical care.<br />

CBR specific areas of interest include:<br />

• applying emerging biotechnologies to the study of blood <strong>and</strong> blood processing for the creation of new knowledge in transfusion science<br />

• developing safer means of removing excess iron from blood<br />

• identifying risk factors, biomarkers <strong>and</strong> therapies for innate immune, inflammatory, malignant, hemostatic <strong>and</strong> thrombotic disorders<br />

• developing novel approaches to repair vascular system abnormalities; designing microbe-resistant drugs for a range of viruses, parasites<br />

<strong>and</strong> bacteria<br />

• restoring organ function with stem cell technologies<br />

• modulating the immune system for better management of chronic inflammatory diseases<br />

• improving drug production technologies<br />

• establishing integrated research <strong>and</strong> clinical training programs to better manage the significant medical problems that confront our<br />

society.<br />

CMMT is focused on exploring the genetic basis of disease <strong>and</strong> translating this knowledge into new treatment strategies for common <strong>and</strong><br />

neglected diseases. CMMT works in the fields of developmental biology, neurobiology, lipid biology, bioinformatics, pharmacogenomics,<br />

epigenetics, <strong>and</strong> transgenics. It is a leader in Huntingdon’s disease research <strong>and</strong> the development of biomarkers to identify adverse drug<br />

reactions (ADRs). The Canadian Pharmacogenomics Network for Drug Safety, operated in conjunction with Pharmaceutical Outcomes<br />

<strong>and</strong> Policy Innovations, Children’s <strong>and</strong> Women’s Health Centre of B.C. (see below), is a nation-wide program that aims to identify genetic<br />

markers that are predictive of severe ADRs <strong>and</strong> implement these in cost-effective diagnostic screening programs to reduce the occurrence<br />

of permanent disability <strong>and</strong> deaths from severe ADRs.<br />

CMMT is part of the UBC Faculty of Medicine <strong>and</strong> is located at the Child <strong>and</strong> Family Research Institute (CFRI) (see above).<br />

CTAG is a genomics <strong>and</strong> molecular pathology core facility supported by a world class team of molecular pathologists. Its mission is to<br />

develop novel laboratory tests to improve the management of a diverse spectrum of disorders including cancer, infectious diseases, <strong>and</strong><br />

inherited syndromes.<br />

CTAG operates at PHSA agencies including the B.C. Cancer Agency, B.C. Centre for Disease Control, B.C. Children’s Hospital <strong>and</strong> B.C. Women’s<br />

Hospital & Health Centre. CTAG offers a broad range of analytical services to the public <strong>and</strong> private sectors.


278<br />

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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Institute of Applied<br />

Physical Activity <strong>and</strong><br />

Health Research<br />

www.educ.uvic.ca/<br />

phed/iapahr/<br />

Joan Wharf Higgins<br />

Canada Research Chair, Health &<br />

Society, UVic<br />

Tel: 250-721-8377<br />

jwharfhi@uvic.ca<br />

Located at UVic. Engaged in a variety of research studies investigating issues related to physical activity, healthy eating, health education<br />

<strong>and</strong> literacy, social marketing, health promotion, <strong>and</strong> population health. Housed within the Institute are the Knowledge Exchange<br />

Research Unit, the Movement Skills Analysis Lab, <strong>and</strong> the Exercise Physiology Lab.<br />

Michael Smith Genome<br />

<strong>Sciences</strong> Centre (GSC),<br />

BCCA<br />

www.bcgsc.ca<br />

The Dr. Tong Louie<br />

Living Laboratory<br />

www.sfu.ca/livinglab<br />

UVic - Genome B.C.<br />

Proteomics Centre<br />

www.proteincentre.<br />

com<br />

B.C. Cancer Research Centre<br />

675 West 10th Avenue, Vancouver,<br />

B.C., V5Z 1L3<br />

Tel: 604-675-8150<br />

Echelon Building<br />

570 West 7th Ave - Suite 100, Vancouver,<br />

B.C., V5Z 4S6<br />

Tel: 604-707-5800<br />

Marco Marra, Director<br />

Tel: 604- 707-5900 x 6082<br />

Tel: 604- 675- 8150 x 8162<br />

mmarra@bcgsc.ca<br />

7th Floor, BCIT DTC<br />

555 Seymour Street<br />

Vancouver, B.C. V5M 3B3<br />

Tel: 778-782-5062<br />

Fax 778-782-5066<br />

Contact Andrew Sixsmith<br />

sixsmith@sfu.ca<br />

University of Victoria Proteomics<br />

Centre<br />

Vancouver Isl<strong>and</strong> Technology Park<br />

#3101-4464 Markham St<br />

Victoria, B.C. V8Z 7X8<br />

Tel: 250-483-3226<br />

info@proteincentre.com<br />

Christoph Borchers, Facility Director<br />

Tel: 250-483-3221<br />

christoph@proteincentre.com<br />

The GSC is a leading international centre for genomics <strong>and</strong> bioinformatics research. Its m<strong>and</strong>ate is to advance knowledge about cancer <strong>and</strong><br />

other diseases, to improve human health through disease prevention, diagnosis <strong>and</strong> therapeutic approaches, <strong>and</strong> to realize the social <strong>and</strong><br />

economic benefits of genomics research. Technology platforms include:<br />

• Bioinformatics<br />

• Sequencing<br />

• Physical mapping<br />

• Affymetrix microarray<br />

• Illumina sequencing<br />

• Proteomics<br />

• Expression cloning<br />

• Drug discovery.<br />

A research facility in the Simon Fraser University’s Gerontology Research Centre <strong>and</strong> the British Columbia Institute of Technology’s Technology<br />

Centre. It evaluates <strong>and</strong> assists in the design <strong>and</strong> operational risk for medical <strong>and</strong> biomechanical devices. It evaluates orthotics,<br />

biomechanical risk, mobility-impairment.<br />

The Lab conducts research <strong>and</strong> training activities that aim to improve the relationship between people <strong>and</strong> their living <strong>and</strong> working<br />

environments. The scope of research extends from gerontology to engineering, <strong>and</strong> from field studies to laboratory simulation to medical<br />

<strong>and</strong> assistive device development.<br />

UVic - Genome B.C. Proteomics Centre is a state-of-the-art proteomics research facility. It is the longest operating proteomics core<br />

facility in Canada, having been in operation since 1982, <strong>and</strong> serves clients in academia, industry <strong>and</strong> government on a fee-for-service <strong>and</strong><br />

collaborative basis. Featured services include:<br />

• Biomarker Discovery <strong>and</strong> Validation<br />

• MALDI Imaging<br />

• Quantitative Proteomics<br />

• Structural Proteomics<br />

• Peptide Synthesis<br />

• Protein Characterization<br />

• Protein Identification<br />

• Bioinformatics<br />

• Metabolomics.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

279<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

University of Victoria<br />

School of Health Information<br />

Science (HIS)<br />

http://hinf.uvic.ca/<br />

The Vancouver Prostate<br />

Centre - Genome<br />

B.C. Microarray Facility<br />

www.microarray.<br />

prostatecentre.com<br />

PO Box 3050 STN CSC<br />

Victoria B.C. V8W 3P5<br />

Tel: 250-721-8575<br />

his@uvic.ca<br />

Abdul Roudsari, Director<br />

The Vancouver Prostate Centre (see<br />

above)<br />

Contact: Colin Collins<br />

Tel: 604-875-4111 x 67536<br />

ccollins@prostatecentre.com<br />

HIS provides a consultative service to the health care community, as well as academic programs (see <strong>Clinical</strong> <strong>Trials</strong> Training Facilities,<br />

below). The School’s view of health information encompasses clinical, sociological, epidemiological, administrative, legal, <strong>and</strong> economic<br />

perspectives. Health is seen from a community perspective <strong>and</strong> encompasses the full range of services including health promotion <strong>and</strong><br />

disease prevention, home care, community health <strong>and</strong> occupational health, physicians services, institutional acute care, rehabilitation <strong>and</strong><br />

extended care.<br />

The Vancouver Prostate Centre’s Microarray Facility is a multi-platform facility that provides research projects with services ensuring<br />

the successful design, execution <strong>and</strong> interpretation of microarray experiments. The facility offers commercial (Agilent, Illumina <strong>and</strong><br />

NimbleGen) whole-genome <strong>and</strong> custom high-density microarrays for gene expression, miRNA, copy number variation <strong>and</strong> epigenetic<br />

studies. Exon capture arrays were recently added which when integrated with next generation sequencing technologies, will make whole<br />

genome <strong>and</strong> targeted re-sequencing studies possible.<br />

The Facility is recognized as an expert in the design <strong>and</strong> use of custom spotted cDNA, oligonucleotide <strong>and</strong> protein microarrays, <strong>and</strong> in the<br />

analysis of the resulting data. Moreover, the facility has added software that allows seamless cross-platform integration <strong>and</strong> analysis of<br />

expression, genomic <strong>and</strong> next generation sequence data making extremely powerful <strong>and</strong> comprehensive studies possible.<br />

14. HEALTH POLICY, EPIDEMIOLOGY, AND HEALTH ECONOMICS RESEARCH CENTRES<br />

Centre for <strong>Clinical</strong><br />

Epidemiology & Evaluation<br />

VCHRI<br />

www.c2e2.vchri.ca<br />

7th Floor, 828 West 10th Avenue<br />

Research Pavilion<br />

Vancouver B.C. V5Z 1M9<br />

Tel: 604-875-4043<br />

Fax: 604-875-5179<br />

C2E2@vch.ca<br />

C2E2 <strong>Clinical</strong> Research Unit VCHRI<br />

Contact: Connie Feschuk, Manager<br />

Tel: 604-875-5886<br />

Fax: 604- 875-5336<br />

connie.feschuk@vch.ca<br />

C2E2 exists to facilitate the development of an evidence-based body of knowledge, its implementation <strong>and</strong> the evaluation of subsequent<br />

outcomes. C2E2 supports clinical research <strong>and</strong> evaluation of clinical programs <strong>and</strong> provides expertise in clinical research methodology <strong>and</strong><br />

statistics to other VCHRI investigators <strong>and</strong> health care policy makers<br />

C2E2 research activities are in five areas:<br />

• Systematic reviews<br />

• <strong>Clinical</strong> research methodology, data management <strong>and</strong> data analysis<br />

• Health services <strong>and</strong> outcomes research<br />

• Health economics<br />

• Health information systems <strong>and</strong> technology<br />

C2E2 Research projects include interests in:<br />

• Respiratory health<br />

• Primary care<br />

• Emergency medicine<br />

• Hip health <strong>and</strong> mobility<br />

• Cardiac surgery<br />

• Orthopedics.<br />

• Trauma


280<br />

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APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Centre for Health Evaluation<br />

<strong>and</strong> Outcome<br />

<strong>Sciences</strong> (CHEOS)<br />

www.cheos.ubc.ca<br />

CIHR Canadian HIV<br />

<strong>Trials</strong> Network<br />

www.hivnet.ubc.ca<br />

Collaboration for<br />

Outcomes Research<br />

<strong>and</strong> Evaluation (CORE),<br />

UBC<br />

http://www.core.ubc.<br />

ca/index.php<br />

St. Paul’s Hospital<br />

620B - 1081 Burrard Street<br />

Vancouver, B.C. V6Z 1Y6<br />

Tel: 604- 806- 8678<br />

Fax: 604-806-8674<br />

Orr, John, Director of Operations<br />

Tel: 604-806-2294<br />

johnorr@mail.cheos.ubc.ca<br />

620B - 1081 Burrard Street Vancouver,<br />

B.C. V6Z 1Y6<br />

Tel: 604-806-8327<br />

Fax: 604-806-8210<br />

Toll Free: 1-800-661-4664.<br />

Pankovich, Jim, Chief Scientific Officer<br />

Tel: 604-806-8340<br />

jpankovich@mail.hivnet.ubc.ca<br />

Faculty of Pharmaceutical Sci., UBC,<br />

2146 East Mall, Vancouver B.C., V6T<br />

1Z3<br />

Tel: 604-827-3674<br />

Fax: 604-827-4014<br />

St Paul’s Hospital,<br />

620B 1081 Burrard St., Vancouver B.C.<br />

V6Z 1Y6, 5th Floor<br />

Marra, Carlo, Director<br />

Tel: 604-827-3398<br />

Carlo.marra@ubc.ca<br />

Westl<strong>and</strong>, Kristin.<br />

Tel: 604-822-9460 westl<strong>and</strong>@<br />

exchange.ubc.ca<br />

Provides services for clinical trials, epidemiology, health economics, <strong>and</strong> health outcomes for various therapeutic areas at Providence<br />

Health Care (see Appendix 2 for more information). Expertise includes epidemiology <strong>and</strong> population health. Conducts pharmacoeconomic<br />

analyses. Evaluates, interprets <strong>and</strong> disseminates health outcome information.<br />

Provides clinical trials infrastructure for HIV <strong>and</strong> related conditions (see Appendix 1 for more information). Pharmacoeconomics is a key<br />

activity within the Network, with the Pharmacoeconomics Program Director (Aslam Anis) also holding the position of national co-director<br />

of the whole Network.<br />

A multidisciplinary group of researchers with expertise in clinical pharmacy, pharmacoepidemiology, health economics, health services<br />

research, program evaluation <strong>and</strong> health promotion research. Works in clinical <strong>and</strong> economic research, <strong>and</strong> pharmaceutical outcomes<br />

assessment.<br />

Established the Community Pharmacist Research Network (CPRN) to capitalize on the availability <strong>and</strong> accessibility of pharmacists in urban<br />

<strong>and</strong> rural communities throughout the province. In the past year, the number of research-oriented community pharmacies in the CPRN has<br />

exp<strong>and</strong>ed from 150 to 187. The CPRN enables the collection of real-time, patient-specific data under conditions of routine clinical care, <strong>and</strong><br />

can be utilized in settings of r<strong>and</strong>omized clinical trials as well as prospective <strong>and</strong> longitudinal studies. Post-marketing data on tolerability,<br />

adherence, <strong>and</strong> effectiveness of medications can be efficiently obtained <strong>and</strong> the field study data linked to medical office records <strong>and</strong> the<br />

B.C. Linked Health Databases.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

281<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Centre of Excellence<br />

for Simulation Education<br />

& Innovation<br />

(CESEI)<br />

www.cesei.org<br />

Centre for International<br />

Health (CIH)<br />

www.cih.ubc.ca<br />

Division of Mathematical<br />

Modeling, UBC/<br />

B.C. Centre for Disease<br />

Control (BCCDC)<br />

http://www.mathmodeling.cdc.ubc.ca/<br />

index.htm<br />

3602-910 W. 10th Avenue<br />

Vancouver, B.C. V5Z 1M9<br />

Fax: 604-875-5832<br />

info@cesei.org<br />

Director of CESEI<br />

Karim Qayumi<br />

Tel: 604-875-5176<br />

qayumi@interchange.ubc.ca<br />

Contact: Marlene Woschee, CESEI<br />

Manager<br />

Tel: 604-875-4499<br />

woschee@interchange.ubc.ca<br />

430 – 2206 East Mall, UBC<br />

Vancouver B.C. V6T 1Z3<br />

Tel: 604-822-8952<br />

Fax: 604-822-9210<br />

ghealth@interchange.ubc.ca<br />

Dr. Jerry Spiegel, Director<br />

Contact: Karen Lockhart, Research<br />

Manager<br />

karen.lockhart@ubc.ca<br />

BCCDC<br />

655 West 12th Ave<br />

Vancouver B.C. V5Z 4R4<br />

English, Krista. Program Manager.<br />

T: 604-707-2476<br />

krista.english@bccdc.ca<br />

CESEI at Vancouver Coastal Health is an internationally recognized multi-disciplinary academic centre in medical education <strong>and</strong> research<br />

related to educational technology.<br />

CESEI is a high-tech classroom for medical students, physicians, nurses, Canadian Forces medical technicians <strong>and</strong> other health care workers.<br />

The subject matter ranges from basic patient interview skills learned by junior medical students to leading edge surgical techniques<br />

acquired by experienced surgeons.<br />

CESEI benefits surgical <strong>and</strong> non-surgical disciplines including:<br />

• Departments of Medicine<br />

• Anaesthesiology<br />

• Continuing Nursing Education<br />

• Obstetrics <strong>and</strong> Gynaecology<br />

• Ophthalmology<br />

• Emergency Medicine<br />

• Acute Care<br />

• Orthopaedics<br />

• Faculty of Applied <strong>Sciences</strong><br />

CESEI research is multidisciplinary, <strong>and</strong> includes the Departments of Surgery, <strong>and</strong> Medicine, Division of Educational Support <strong>and</strong> Development<br />

(Faculty of Medicine), Department of Mechanical Engineering (Faculty of Applied Science at UBC), Faculty of Computer Science<br />

(McGill University), School of Engineering Science (SFU), Centre for Minimal Access Surgery (CMAS) at McMaster University.<br />

CESEI industry partners committed to collaborate in these projects are MacDonald Dettwiler & Associates (MDA), Intuitive Surgical <strong>and</strong><br />

Medical Education Technologies Inc. (METI).<br />

CIH is an organising centre for a broad network of members in the UBC community interested in international health. CIH is a unit of the<br />

College of Health Disciplines in collaboration with the Liu Institute for Global Issues. CIH aims to stimulate <strong>and</strong> support the contribution of<br />

UBC faculty, students <strong>and</strong> staff to better <strong>and</strong> more equitable health worldwide through the translation of knowledge into action:<br />

• Raise awareness of global health challenges <strong>and</strong> opportunities for tackling them<br />

• Stimulate greater involvement of UBC faculty students, <strong>and</strong> partners in international health.<br />

• Encourage excellence in research, capacity development, practice <strong>and</strong> knowledge translation for improving global health.<br />

Develops innovative mathematical tools to better underst<strong>and</strong> <strong>and</strong> control the spread of infectious diseases. Provides mathematical<br />

modeling expertise to public health policy makers in B.C.; builds infectious disease transmission models to assist policy design in Canada.<br />

Projects include modeling HPV & influenza immunization strategies, treatments for HIV, hepatitis C <strong>and</strong> syphilis.


282<br />

BRITISH COLUMBIA<br />

APPENDIX 9. Healthcare Research Centres (cont’d)<br />

RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

Pharmaceutical<br />

Outcomes <strong>and</strong> Policy<br />

Innovations, Children’s<br />

<strong>and</strong> Women’s Health<br />

Centre of B.C.<br />

POPi<br />

www.popi.ubc.ca<br />

University of Victoria<br />

Pharmaceutical<br />

Outcomes <strong>and</strong> Policy<br />

Innovation<br />

POPI<br />

(no URL)<br />

UBC Centre for Health<br />

Services <strong>and</strong> Policy<br />

Research (CHSPR)<br />

www.chspr.ubc.ca<br />

The Pharmaceutical Outcomes<br />

Programme<br />

Children’s <strong>and</strong> Women’s Health Centre<br />

of B.C.<br />

E423-4480 Oak Street, Vancouver<br />

B.C., V6H 3V4<br />

Dr. Bruce Carleton, Director<br />

Tel: 604-875-3609<br />

bcarleton@popi.ubc.ca<br />

Public Administration/Human <strong>and</strong><br />

Social Development<br />

University of Victoria<br />

PO Box 1700 STN CSC<br />

Victoria B.C. V8W 2Y2<br />

Tel: 250-721-8066<br />

Fax: 250-721-8849<br />

Contact: Rebecca Warburton,<br />

Assistant Professor<br />

rnwarbur@uvic.ca<br />

201-2206 East Mall<br />

Vancouver B.C. V6T 1Z3<br />

Tel: 604-822–4969<br />

Fax: 604-822–5690<br />

enquire@chspr.ubc.ca<br />

Director, Maurice Barer<br />

Tel: 604-822-5992<br />

Contact: Vanessa Chu, Communications<br />

Specialist<br />

Tel: 604-822–6668<br />

vchu@chspr.ubc.ca<br />

This pediatric research unit operates out of the B.C. Children’s Hospital in association with the Faculty of Paediatrics at UBC. Its mission is to<br />

foster pharmaceutical policy innovation through proactive policy research, training <strong>and</strong> knowledge translation concerning the effectiveness,<br />

safety <strong>and</strong> cost management of prescription drugs. POPi has 3 general components: Drug Safety, Drug Effectiveness, Drug Policy.<br />

The goal of POPi’s Director, Dr. Bruce Carleton, is to make medication use more effective <strong>and</strong> safer for all patients, particularly children. His<br />

research focus is on the impact of drug therapy on human health <strong>and</strong> quality of life. He is particularly interested in developing better ways<br />

to evaluate the effectiveness of drugs, medication-use models designed to improve patient health, as well as practical surveillance systems<br />

to improve the safe use of medication.<br />

Pharmaceutical Outcomes <strong>and</strong> Policy Innovation (POPI) Research Unit studies drug effectiveness, safety <strong>and</strong> costs to provide<br />

decision makers with cost effective drug coverage strategies that produce the best health outcomes. Much of the work has a focus on<br />

pharmaceutical use by children <strong>and</strong> seniors, two populations particularly at risk for adverse drug reactions.<br />

POPI unit has access to the largest prescription database in Canada: B.C.’s PharmaNet system has captured all prescription drug purchases<br />

by B.C. residents since 1995, <strong>and</strong> can be linked to other databases with information on physician services, hospital care <strong>and</strong> vital statistics.<br />

POPI recommends improvements in clinical <strong>and</strong> public policy, including studying trends <strong>and</strong> regional variations in asthma care <strong>and</strong><br />

patient compliance with treatment; examining how to assess “real life” drug effectiveness in patients who may have multiple medical conditions,<br />

especially seniors; evaluating five provincial drug plans to determine optimal policies; evaluating the impact of academic detailing,<br />

or educational outreach, on drug prescribing across Canada to identify best practices in detailing programs; <strong>and</strong> identifying trends, safety<br />

concerns <strong>and</strong> research priorities regarding the dispensing of prescription medication to B.C. children.<br />

CHSPR undertakes policy relevant research <strong>and</strong> graduate training, <strong>and</strong> engages <strong>and</strong> informs health policy <strong>and</strong> issues that matter to<br />

Canadians.<br />

CHSPR Research is in scientific enquiry into population health <strong>and</strong> into ways in which health services can best be organized, funded <strong>and</strong><br />

delivered. Researchers <strong>and</strong> staff carry out a diverse program of research <strong>and</strong> development, delivering the tools <strong>and</strong> analyses needed to<br />

renew health care <strong>and</strong> improve the health of Canadians.<br />

CHSPR research interests are in the areas of:<br />

• Health <strong>and</strong> Health Care Use: Investigating population-wide patterns of health <strong>and</strong> health services use<br />

• Health Human Resources: Investigating the supply, distribution <strong>and</strong> service provision of physicians <strong>and</strong> nurses<br />

• Primary Health Care: Developing evidence-based frameworks <strong>and</strong> approaches to underst<strong>and</strong>ing primary health care systems<br />

• Pharmaceutical Policy: Studying the financing, delivery <strong>and</strong> use of prescription drugs<br />

• Workplace Health <strong>and</strong> Safety: Studying ways to improve workplace health <strong>and</strong> safety.


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RESEARCH CENTRE/ URL CONTACT DESCRIPTION<br />

15. ENVIRONMENTAL HEALTH RESEARCH CENTRES<br />

School of Environmental<br />

Health (SOEH), UBC<br />

www.soeh.ubc.ca<br />

The B.C. Environmental<br />

<strong>and</strong> Occupational<br />

Health Research Network<br />

(BCEOHRN)<br />

www.bceohrn.ca<br />

3rd Floor - 2206 East Mall, UBC<br />

Vancouver, B.C. V6T 1Z3<br />

Tel: 604- 822-9595<br />

Fax: 604-822-9588<br />

Executive Director, Christie Hurrell<br />

Centre for Health <strong>and</strong> Environment<br />

Research<br />

Tel: 604-827-5622<br />

Scientific Director: Dr. Henry Harder<br />

Tel: 250-960-6506<br />

Associate Scientific Director: Dr. Paul<br />

Demers<br />

Tel: 604-.822-0585<br />

pdemers@interchange.ubc.ca<br />

Contact: Executive Director - Ms. Pat<br />

Atherton<br />

Tel: 250-216-7290<br />

patherton@bceohrn.ca<br />

SOEH is a teaching <strong>and</strong> research unit in the College for Interdisciplinary Studies. SOEH primary objective is to prepare professionals <strong>and</strong><br />

researchers with the expertise to evaluate risks from physical, chemical <strong>and</strong> biological exposures <strong>and</strong> the skills <strong>and</strong> sensitivities to effect<br />

changes that will protect human health <strong>and</strong> well-being.<br />

SOEH faculty <strong>and</strong> students have an outst<strong>and</strong>ing record in occupational <strong>and</strong> environmental science research. SOEH research themes include:<br />

• Air pollution • Bioaerosols<br />

• Determinants of exposure • Epidemiology <strong>and</strong> risk regulation<br />

• Knowledge translation • Musculoskeletal injuries <strong>and</strong> claims<br />

• Nanosensors • Noise in the built environment<br />

• Noise <strong>and</strong> heart disease • Occupational carcinogens<br />

• Occupational respiratory disease • Young workers<br />

BCEOHRN was founded in 2005 through an award from the Michael Smith Foundation for Health Research.<br />

BCEOHRN’s Strategic goals include:<br />

• Improved research capacity through enabling inter-institutional collaboration <strong>and</strong> seed funding to develop innovative research ideas.<br />

• Student support by providing funding (travel bursaries, pilot funding, team building grants) <strong>and</strong> a mentorship program.<br />

• Improved knowledge transfer by hosting two meetings per year that bring together stakeholders (researchers, educators, policy makers,<br />

trainees) to address occupational <strong>and</strong> environmental health issues that are priorities to British Columbians.<br />

BCEOHRN Network is currently comprised of over 1,000 members from across the province. Detailed information about our members can<br />

be viewed at our members’ database available by clicking the button at the top of any page on our website. Members are:<br />

• University-based <strong>and</strong> community-based researchers from many disciplines<br />

• Research trainees <strong>and</strong> students<br />

• People who work in environmental <strong>and</strong> occupational health fields, <strong>and</strong> are interested in research<br />

• Service providers<br />

• Policy-makers, including local <strong>and</strong> regional health authority representatives.


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APPENDIX 10. NATIONAL AND INTERNATIONAL NETWORKS WHICH HAVE B.C.<br />

CLINICAL INVESTIGATORS AS PIVOTAL PLAYERS OR MEMBERS<br />

This Appendix contains two tables. The first lists national <strong>and</strong> international networks in which B.C.’s clinical investigators play a pivotal role. The second<br />

is a non-exclusive list of Networks to which B.C.’s investigators belong but are not on Executive or other Committees.<br />

Networks In Which B.C.’s <strong>Clinical</strong> Investigators Play a Pivotal Role<br />

Examples of National <strong>and</strong> International Networks In Which B.C.’s <strong>Clinical</strong> Investigators Play a Pivotal Role<br />

Network Description<br />

CNS<br />

National<br />

Canadian Network of Multiple Sclerosis Clinics (http://cnmsc.<br />

org/Canadian-Network-Of-Multiple-Sclerosis-Clinics.aspx)<br />

Canadian Northwest FASD Partnership<br />

(www.cnfasdpartnership.ca)<br />

Academic <strong>and</strong> community based clinics established for the advancement of patient services, education, <strong>and</strong> research in<br />

MS. VCHRI’s Dessa Sadovnick is on the Executive Committee.<br />

Under the leadership of CFRI in Vancouver, this network includes researchers in B.C., Alberta, Saskatchewan, Manitoba,<br />

<strong>and</strong> the 3 northern territories. More than 150 research protocols pertaining to Fetal Alcohol Spectrum Disorder (FASD)<br />

are active within the network.<br />

Canadian Stroke Consortium (www.strokeconsortium.ca) Academic alliance committed to the pursuit of anti-stroke therapies, Chaired by UBC’s Phil Teal (Director of the B.C.<br />

Centre for Stroke <strong>and</strong> Cerebrovascular Diseases) <strong>and</strong> involving over 135 Canadian neurologists <strong>and</strong> research consultants.<br />

Canadian Stroke Network (www.canadianstrokenetwork.ca) Canadian Federal government Network of Centres of Excellence (NCE) based in Ottawa involved in stroke research. Brian<br />

MacVicar, UBC, is one of the Theme Leaders (he does not work in clinical trials).<br />

NeuroDevNet (www.neurodevnet.ca) This pan-Canadian NCE is focused on FASD, autism, <strong>and</strong> cerebral palsy. It is led by Dan Goldowitz of CMMT <strong>and</strong> CFRI (he<br />

does not work in clinical trials). It involves clinicians <strong>and</strong> scientists from across Canada who are dedicated to studying<br />

children’s brain development from both basic science <strong>and</strong> clinical perspectives.<br />

PrioNet Canada (www.prionetcanada.ca) Based at UBC in Vancouver, this NCE is dedicated to prion research <strong>and</strong> directed by UBC’s Neil Cashman (he does not work<br />

in clinical trials). Has researchers at nine Canadian universities (from Prince Edward Isl<strong>and</strong> to B.C.), two foreign universities,<br />

23 government departments <strong>and</strong> agencies, <strong>and</strong> 8 industrial partners.<br />

International<br />

Pacific Rim Workgroup Against Epilepsy (no URL) CFRI’s Peter Wong is a founding member.


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Network Description<br />

Cancer/ Hematology<br />

National<br />

The C17 Council (www.c17.ca) Organization composed of the institutionally appointed heads of the 16 pediatric hematology, oncology, <strong>and</strong> stem<br />

cell transplantation programs in Canada. Acts as an authoritative Canadian voice representing the interests of children<br />

<strong>and</strong> adolescents with cancer <strong>and</strong> blood disorders. CFRI’s Paul Rogers is one of the Council members <strong>and</strong> Co-Chair of the<br />

Cancer Care for Adolescents <strong>and</strong> Young Adults Committee.<br />

Canadian Blood & Marrow Transplant Group (www.cbmtg.org) National, voluntary, multi-disciplinary organization providing leadership <strong>and</strong> promoting excellence in patient care,<br />

research <strong>and</strong> education in the field of blood <strong>and</strong> marrow transplantation (BMT). CFRI’s Kirk Schultz is a prominent<br />

member.<br />

Canadian Urologic Oncology Group (CUOG) (www.cuog.org) Created, owned <strong>and</strong> operated by its members, CUOG is a clinical research investigator network. The Consortium is a national<br />

alliance of leading academic <strong>and</strong> community based urologists, medical oncologists, <strong>and</strong> radiation oncologists. It is<br />

headquartered in Vancouver. VGH’s Martin Gleave is past Chair of <strong>and</strong> a continuing member of the Executive Committee;<br />

BCCA’s Tom Pickles <strong>and</strong> Kim Chi are members of the Executive Committee.<br />

Children’s Oncology Group (COG) (www.childrensoncologygroup.org)<br />

National Cancer Institute of Canada <strong>Clinical</strong> <strong>Trials</strong> Group (NCIC<br />

CTG) (www.cancer.ca/research/)<br />

International<br />

Australian-Canadian Prostate Cancer Research Alliance (www.<br />

aus-canprostatealliance.org)<br />

National Cancer Institute (U.S.)-Canada <strong>Clinical</strong> <strong>Trials</strong> Group<br />

(www.cancer.gov/cancertopics/factsheet/NCI/clinical-trialscooperative-group)<br />

Pediatric Bone <strong>and</strong> Marrow Transplant Consortium (PBMTC)<br />

(www.pbmtc.org)<br />

International group sponsored by the US National Cancer Institute that conducts epidemiologic, clinical <strong>and</strong> translational<br />

research in pediatric cancer. CFRI’s Paul Rogers is a prominent member.<br />

The NCIC CTG is funded by the NCIC (now Canadian Cancer Society Research Institute) through its world-renowned peer<br />

review process. A number of B.C. investigators are on various NCIC CTG Executive Committees. BCCA’s Kim Chi is on the<br />

Genitourinary (GU) Disease Site Executive Committee; Chair of the sub-site Advanced Prostate group; <strong>and</strong> Executive<br />

Committee Member <strong>and</strong> Chair-elect of the Investigational New Drug Site; Stephen Chia is on the <strong>Clinical</strong> <strong>Trials</strong> Committee<br />

<strong>and</strong> Breast Site Executive Committee; Hagan Kennecke is on the GI Executive Committee; Christopher Lee is on the<br />

Lung Site Executive Committee; Martin Gleave is past Chair of <strong>and</strong> continues to be a member of the GU <strong>Clinical</strong> <strong>Trials</strong><br />

Group Executive Committee.<br />

International network of Australian <strong>and</strong> Canadians who can coordinate their skills <strong>and</strong> solve the complex problems facing<br />

prostate cancer. The Vancouver Prostate Centre is the Canadian Hub of this alliance <strong>and</strong> a founding member.<br />

The <strong>Clinical</strong> <strong>Trials</strong> Cooperative Group Program, sponsored by the National Cancer Institute (NCI), promotes <strong>and</strong> supports<br />

clinical trials of new cancer treatments, explores methods of cancer prevention <strong>and</strong> early detection, <strong>and</strong> studies qualityof-life<br />

issues <strong>and</strong> rehabilitation during <strong>and</strong> after treatment. Cooperative groups include researchers, cancer centres, <strong>and</strong><br />

community physicians throughout the U.S, Canada, <strong>and</strong> Europe. A number of B.C. investigators are on NCI Executive<br />

Committees. BCCA’s Kim Chi is on the Prostate Cancer Task Force Committee; Hagan Kennecke is on the Neuroendocrine<br />

Task Force Committee.<br />

CFRI’s Kirk Schultz is past Chair.. A voluntary group of clinicians <strong>and</strong> scientists that includes over 100 pediatric PBMTC<br />

centres in North America, Australia <strong>and</strong> New Zeal<strong>and</strong>. Purpose is to engage in scientific <strong>and</strong> educational activities<br />

related to the use of hematopoietic stem cells in the treatment of diseases of children <strong>and</strong> adolescents.


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Networks In Which B.C.’s <strong>Clinical</strong> Investigators Play a Pivotal Role (cont’d)<br />

Network Description<br />

Infectious Diseases<br />

National<br />

CAIRE - Canadian Association for Immunization Research<br />

(www.caire.ca)<br />

Canadian Immunization Monitoring Program, Active (IMPACT)<br />

(www.cps.ca/English/surveillance/impact/impact.htm)<br />

Chair: Scheifele, David. Based at CFRI, Vancouver. CAIRE is a professional organization of Canadian vaccine researchers.<br />

Many of the members are involved in applied vaccinology, i.e., evaluating new vaccines, building the rationale for new<br />

public programs <strong>and</strong> optimizing public immunization programs.<br />

Pediatric hospital-based national active surveillance network for adverse events following immunization, vaccine failures<br />

<strong>and</strong> selected infectious diseases in children that are, or are soon to be, vaccine preventable. Consists of 12 Canadian<br />

centres. The IMPACT data centre is located in Vancouver, B.C.<br />

CIHR Canadian HIV <strong>Trials</strong> Network (www.hivnet.ubc.ca) Based at St Paul’s Hospital, Vancouver B.C. National Director: Martin Schechter, PHCRI. Partnership of clinical investigators,<br />

physicians, nurses, people living with HIV/AIDS, pharmaceutical manufacturers <strong>and</strong> others that facilitates HIV/AIDS<br />

clinical trials; have centres in 30 clinics <strong>and</strong> hospitals stretching across the country from Nova Scotia to B.C. (see also<br />

Appendices 1 <strong>and</strong> 10 [section 4]).<br />

Pan-Provincial Vaccine Enterprise (PREVENT) http://www.<br />

prevent-cecr.ca/<br />

Pediatric Investigators Collaborative Network on Infections<br />

in Canada (see www.ncbi.nlm.nih.gov/pmc/articles/<br />

PMC2827737/)<br />

PrioNet Canada (www.prionetcanada.ca) Based at UBC, Vancouver B.C. See above for details.<br />

Public Health Agency of Canada - Canadian Institutes of<br />

Health Research Influenza Research Network (PCIRN) (www.<br />

pcirn.ca)<br />

International<br />

Based in Saskatoon, this incorporated Canadian non-profit organization identifies promising vaccine c<strong>and</strong>idates<br />

targeting Canada's public health priorities <strong>and</strong> works with industry partners to develop these vaccine c<strong>and</strong>idates for the<br />

marketplace. PREVENT conducts time <strong>and</strong> labour intensive preclinical <strong>and</strong> early-stage clinical trials for promising vaccine<br />

c<strong>and</strong>idates, reducing the risk by facilitating critical mid-stage vaccine development. A Canadian western regional<br />

office is located at BCCDC, Vancouver.<br />

Network established to answer significant questions in a timely manner. Canada’s small population relative to its large<br />

geographic area makes it nearly impossible for a single centre to have the sample numbers necessary to answer such<br />

questions. Consists of many pediatric centres across Canada. BCCH’s David Scheifele is a leading member.<br />

A pan-Canadian vaccine research network that conducts applied public health research in preparation for <strong>and</strong> during an<br />

influenza p<strong>and</strong>emic. The Rapid Vaccine <strong>Trials</strong> are led by David Scheifele of CFRI <strong>and</strong> BCCDC.<br />

SARS Accelerated Vaccine Initiative (SAVI) (www.savi-info.ca) Based at BCCDC <strong>and</strong> UBC, this B.C.-led international consortium of organizations <strong>and</strong> individuals is working to fast track<br />

the development of a SARS vaccine.<br />

Maternal <strong>and</strong> Child Health (Not Disease Specific)<br />

National<br />

Canadian Mother Infant Child Youth Research Network (MI-<br />

CYRN) (www.micyrn.ca)<br />

Directed by Anne Junker, CFRI, Vancouver B.C. Multi-disciplinary initiative to support world-class clinical research<br />

nationwide, connecting. 17 academic child/child-maternal health centres across Canada. Primary objectives are to build<br />

innovative platforms to address gaps in the clinical research environment through the establishment of core programs<br />

in research partnerships, training, knowledge translation, research methods, research ethics <strong>and</strong> regulatory affairs, <strong>and</strong><br />

funding partnerships. Also sets out to establish integrated access to innovative tools in data management, genomics,<br />

<strong>and</strong> biobanking.


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Network Description<br />

Canadian Neonatal Followup Network (CFUN) (www.cnfun.ca) Voluntary collaboration between Neonatal <strong>and</strong> Perinatal Follow-Up Programs in Canada <strong>and</strong> their multidisciplinary<br />

team members. Developed in liaison with the Canadian Neonatal Network to facilitate collaboration in research,<br />

integrated data collection, knowledge translation <strong>and</strong> to improve the quality of care <strong>and</strong> long term outcomes of children<br />

seen in their programs. CFRI’s Anne Synnes is the Director <strong>and</strong> chairs the Steering Committee <strong>and</strong> Database Working<br />

Group.<br />

Canadian Neonatal Network (www.canadianneonatalnetwork.org)<br />

Canadian Pediatric Anesthesiology Research Network (www.<br />

micyrn.ca/documents/PINC Meeting Report November 5 2009.<br />

pdf)<br />

Canadian Pediatric Surgery Network (CAPSnet) (www.capsnetwork.org)<br />

Founded by ex-CFRI investigator, Shoo Lee. Now includes members from 30 hospitals (neonatal nurseries) <strong>and</strong> 17<br />

universities across Canada. The Network maintains a st<strong>and</strong>ardized neonatal intensive care unit (NICU) database <strong>and</strong> provides<br />

a unique opportunity for researchers to participate in collaborative projects on a national <strong>and</strong> international scale.<br />

Network to advance excellence in pediatric research in Canada on the big questions that require collaborative research.<br />

CFRI investigator Gillian Lauder is a co-founder. Others, including Martin Ansermino, are members.<br />

Multi-disciplinary group of Canadian health researchers working together on research issues concerning pediatric surgical<br />

care. To date there are 26 network members of which the majority are leading pediatric surgeons/surgical educators<br />

in their field. The network comprises all 16 tertiary perinatal centres in Canada. Founded by CFRI’s Eric Skarsgard <strong>and</strong><br />

coordinated by B.C. Children’s Hospital.<br />

Canadian Perinatal Network (www.cpn-rpc.org) Members from 22 tertiary perinatal units from across Canada collaborate on research issues relating to perinatal care,<br />

particularly hypertension in pregnancy <strong>and</strong> the prevention of preeclampsia. Led by Rob Liston <strong>and</strong> Laura Magee, CFRI,<br />

Vancouver.<br />

International<br />

International Alliance for Better Medicines for Children (no<br />

URL)<br />

A network of advocacy groups from around the world which advocate for better medicines for all children. It works<br />

closely with the World Health Organization, UNICEF, <strong>and</strong> the Bill & Melinda Gates Foundation. Leadership provided by<br />

Stuart MacLeod <strong>and</strong> Bob Peterson at CFRI (do not conduct clinical trials).<br />

North American Fetal Therapy Network (www.naftnet.org) Voluntary association of medical centres in the United States <strong>and</strong> Canada with established expertise in fetal surgery <strong>and</strong><br />

other forms of multidisciplinary care for complex disorders of the fetus. CFRI’s Alain Gagnon is a founding member.<br />

Other<br />

National<br />

Canadian Thoracic Society (www.lung.ca/cts-sct/aboutpropos_e.php)<br />

Promotes lung health by supporting the respiratory community through leadership, collaboration, research, learning<br />

<strong>and</strong> advocacy, <strong>and</strong> promoting the best respiratory practices in Canada. VCHRI’s Mark Fitzgerald is on Executive Committee;<br />

VCHRI’s Jeremy Road is Chair of Research Committee.<br />

Canadian Urological Association (CUA) (www.cua.org) Represents <strong>and</strong> provides a voice for all Canadian urologists <strong>and</strong> fosters dedication of all members of the profession<br />

toward ensuring the highest possible st<strong>and</strong>ard of urologic care for Canadians. The Vancouver Prostate Centre’s Martin<br />

Gleave is Chair of the CUA Scholarship Foundation Research Council.


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Networks In Which B.C.’s <strong>Clinical</strong> Investigators Play a Pivotal Role (cont’d)<br />

Network Description<br />

Canadian Alliance of Pediatric Rheumatology Investigators<br />

(CAPRI) (www.icaare.ca/index.phpoption=com_content&tas<br />

k=view&id=44&Itemid=80)<br />

International<br />

Network investigating childhood arthritis in Canada. Obtained CIHR funding for “Determinants of Risk <strong>and</strong> Outcome in<br />

Inflammatory Arthritis”, REACCH OUT (quality of life <strong>and</strong> outcomes in juvenile arthritis), <strong>and</strong> BBOP (Biologically Based<br />

Outcome Predictors) in Juvenile Idiopathic Arthritis. CFRI’s David Cabral is a member of the interim steering committee;<br />

<strong>and</strong> Lori Tucker is a PI on REACCH OUT.<br />

American Bronchology Association (www.aabronchology.org) Promoties excellence in clinical care, education, <strong>and</strong> research in the rapidly exp<strong>and</strong>ing fields of Bronchoscopy, Interventional<br />

Pulmonology, <strong>and</strong> Interventional Bronchoscopy. VCHRI’s Stephen Lam is past Director.<br />

Canadian Pharmacogenomics Network for Drug Safety A joint initiative of POPi <strong>and</strong> CMMT (CFRI), Vancouver B.C. One of only two active adverse drug reaction (ADR) surveillance<br />

networks in the world. Brings together leading scientists from many disciplines within industry, government, universities,<br />

hospitals, <strong>and</strong> research institutes to better underst<strong>and</strong> <strong>and</strong> prevent severe ADRs. Currently recruiting patients<br />

to a trial on adverse drug reactions in children (<strong>Clinical</strong><strong>Trials</strong>.gov identifier: NCT00414115) <strong>and</strong> adults in Canada, US,<br />

Mexico, Europe.<br />

Childhood Arthritis & Rheumatism Research Alliance (CARRA)<br />

(www.carragroup.info; www.arthritis.org/carra.php)<br />

Integrative Analysis of Longitudinal Studies of Aging (IALSA)<br />

Research Network (http://lifelab.tss.oregonstate.edu/)<br />

International Photodynamic Association (IPA) (http://sites.<br />

pcmd.ac.uk/ipa/index.php)<br />

North American organization of pediatric rheumatologists who are building a multi-centre network of pediatric rheumatology<br />

research centres across the continent that will work together on clinical trials <strong>and</strong> research. CFRI’s David Cabral<br />

<strong>and</strong> Lori Tucker are co-founders.<br />

Co-directed by Scott Hofer, Victoria B.C. smhofer@uvic.ca. Collaborative research infrastructure for coordinated<br />

interdisciplinary, cross-national research aimed at replicating <strong>and</strong> extending research findings from a within-person<br />

perspective. The network is currently comprised of over 25 longitudinal studies on aging, spanning eight countries, with<br />

a combined sample size of approximately 70,000 individuals.<br />

Promotes study of diagnosis <strong>and</strong> treatment using light <strong>and</strong> photosensitizers, disseminates such information to members<br />

of IPA, the medical community <strong>and</strong> the general public. Membership consists of the most prominent international<br />

clinicians <strong>and</strong> scientists involved in performing <strong>and</strong> researching photodynamic therapy (PDT) <strong>and</strong> photodiagnosis (PD).<br />

VCHRI’s Stephen Lam is a past President.<br />

National Core for Neuroethics (www.neuroethics.ubc.ca) Based at UBC in Vancouver B.C. The permanent home for the International Neuroethics Network.


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289<br />

Networks In Which B.C.’s <strong>Clinical</strong> Investigators Are Members<br />

(Examples of National <strong>and</strong> International Networks)<br />

Network Description<br />

Cardiology<br />

National<br />

Canadian Heart Failure Network (www.chfn.ca) Established in 1999 to improve the current management of heart failure, implement new proven therapies in a timely<br />

manner, <strong>and</strong> collaborate in innovative research approaches to optimize patient management. Has five B.C. members:<br />

Abbotsford Heart Failure Clinic, Central Okanagan Association for Cardiac Function Office (Kelowna), Penticton Regional<br />

Hospital, Surrey Memorial Hospital, St. Paul’s Hospital.<br />

Western Canadian Children’s Heart Network (www.westernchildrensheartnetwork.ca)<br />

International<br />

Network of pediatric cardiac care providers from the four western provinces – B.C., Alberta, Saskatchewan, <strong>and</strong> Manitoba.<br />

Pediatric cardiac surgery is performed at two centres - Stollery Children's Hospital in Edmonton <strong>and</strong> B.C. Children's<br />

Hospital. Network follows st<strong>and</strong>ard diagnostic, investigation, <strong>and</strong> referral protocols.<br />

Congenital Heart Surgeons Society (www.chss.org) Not-for-profit charitable corporation based in the US that sponsors <strong>and</strong> oversees multi-institutional clinical studies;<br />

links <strong>and</strong> educates investigators; <strong>and</strong> encourages <strong>and</strong> stimulates investigation <strong>and</strong> study that will increase the knowledge<br />

of congenital cardiac physiology, pathology <strong>and</strong> therapy, <strong>and</strong> to correlate <strong>and</strong> disseminate such knowledge.<br />

Pediatric & Congenital Electrophysiology Society (www.pediatricepsociety.org)<br />

International group of physicians <strong>and</strong> allied professionals dedicated to improving the care of children <strong>and</strong> young adults<br />

with cardiac rhythm disturbances. The group's primary mission is to foster high-quality collaborative research <strong>and</strong> exchange<br />

of ideas on arrhythmia topics that are particularly relevant to infants <strong>and</strong> children. BCCH’s Shubhayan Sanatani<br />

is a member.<br />

Pediatric Heart Network (www.pediatricheartnetwork.com) Part of the US’ National Heart, Blood <strong>and</strong> Lung Institute of the NIH. Conducts trials to improve outcomes <strong>and</strong> quality of<br />

life in children who are born with or acquire heart disease.<br />

CNS<br />

National<br />

Canadian Pediatric Epilepsy Network (see http://cjns.metapress.com/app/home/contribution.aspreferrer=parent&bac<br />

kto=issue,11,20;journal,47,70;linkingpublicationresults,1:30<br />

0307,1)<br />

Network of scientists <strong>and</strong> health care professionals in partnership with organizations which provide education <strong>and</strong> support<br />

to children with epilepsy. Objective is to gain a better underst<strong>and</strong>ing of childhood epilepsy through collaborative<br />

research conducted with doctors, psychologists, nurses, social workers, educators <strong>and</strong> scientists across Canada.<br />

Canadian Pediatric Neuromuscular Group N/A<br />

Canadian Consortium of <strong>Clinical</strong> Cognitive Research Centres Nationwide network of 35 clinics that evaluates <strong>and</strong> treats individuals with dementia <strong>and</strong> cognitive disorders.<br />

(C5R) (www.c5r.ca)<br />

Canadian Movement Disorder Group (www.cmdg.org) Canadian clinicians <strong>and</strong> scientists with an interest <strong>and</strong> expertise in the study <strong>and</strong> care of patients with movement<br />

disorders.<br />

Canadian Pediatric Demyelinating Network (no URL) Consists of 22 pediatric care facilities across Canada.


290<br />

BRITISH COLUMBIA<br />

Networks In Which B.C.’s <strong>Clinical</strong> Investigators Are Members (cont’d)<br />

Network Description<br />

International<br />

Alzheimer’s Disease Neuroimaging Initiative (www.nia.nih.<br />

gov/Alzheimers/ResearchInformation/<strong>Clinical</strong><strong>Trials</strong>/ADNI.htm)<br />

A major research study, sponsored by the US NIH, to determine whether brain imaging can help predict onset <strong>and</strong><br />

monitor progression of Alzheimer’s disease.<br />

Consortium of Multiple Sclerosis Satrs (www.mscare.org) Professional organization for MS healthcare providers <strong>and</strong> researchers in North America.<br />

Cancer/ Hematology<br />

National<br />

Canadian Brain Tumor Consortium (www.cbtc.ca) National investigator network of over 40 brain tumour specialists <strong>and</strong> researchers treating both pediatric <strong>and</strong> adult<br />

patients with brain tumour. An integral pillar of the Canadian Brain Tumour Network (CBTNet). CFRI members are<br />

involved in the studies.<br />

Canadian Pediatric Thrombosis & Hemostasis Network (no URL) N/A<br />

International<br />

Breast Cancer International Research Group (www.bcirg.org) Part of the Cancer International Research Group division of TRIO (Translational Research in Oncology), an international,<br />

not-for-profit, academic research organization consisting of an international scientific oncology division known as<br />

Breast Cancer International Research Group (BCIRG) <strong>and</strong> a clinical trial operations branch (CIRG) that serves <strong>and</strong> supports<br />

the scientific division in conducting <strong>and</strong> managing their clinical trials.<br />

Eastern Oncology Cooperative Group (http://ecog.dfci.harvard.<br />

edu)<br />

One of the largest clinical cancer research organizations in the US, conducting multi-centre clinical trials in all types of<br />

adult cancers.<br />

Hemophilia Prophylaxis networks (various) N/A<br />

National Surgical Adjuvant Breast <strong>and</strong> Bowel Project (NSABP). A clinical trials cooperative group supported since by the US National Cancer Institute (NCI).<br />

(www.nsabp.pitt.edu)<br />

Radiation Therapy Oncology Group (RTOG), US (www.rtog.org) RTOG is a key clinical research component of the American College of Radiology (ACR) <strong>and</strong> serves as a multi-institutional,<br />

international clinical cooperative group funded primarily by the National Cancer Institute.<br />

Southwest Oncology Group (SWOG), US (www.swog.org) One of the largest of the NCI-supported cancer clinical trials cooperative groups.<br />

Thalassemia <strong>Clinical</strong> Research Network (www.chori.org/<strong>Clinical</strong>_Studies/Thalassemia/TCRN.html)<br />

Infectious Diseases<br />

National<br />

Canadian Pediatric AIDS Research Group (CPARG) CFRI’s Jack Forbes is a member.<br />

Founded in 1998 by the National Heart Lung <strong>and</strong> Blood Institute (NHLBI), part of the National Institute of Health (NIH),<br />

to provide a US/Canadian structure to conduct clinical studies in thalassemia.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

291<br />

Network Description<br />

Maternal <strong>and</strong> Child Health (Not Disease Specific)<br />

National<br />

Canadian Neonatal <strong>and</strong> Pediatric Nutrition Network (CNPNN)<br />

(no URL)<br />

Established under the CIHR Opportunity Program.<br />

Pediatric Emergency Research Canada (PERC) Network of health care professionals that was formed in 1995 to conduct multi-centre research projects. Currently PERC<br />

has 15 sites situated across Canada within teaching or pediatric hospitals. BCCH’s Ran Goldman is the B.C. representative.<br />

Other<br />

National<br />

Addressing Childhood Obesity through Research & Networking<br />

(ACORN) (no URL)<br />

Canadian Cystic Fibrosis Foundation <strong>Clinical</strong> Studies Network<br />

(CFF-CSN) (www.cysticfibrosis.ca)<br />

Canadian Congenital Anomalies Surveillance Network (CCASN)<br />

(www.phac-aspc.gc.ca/ccasn-rcsac/index-eng.php)<br />

N/A<br />

The Network is part of the Canadian Cystic Fibrosis Foundation, which funds clinical trials <strong>and</strong> research in cystic fibrosis.<br />

National framework to support interdisciplinary collaboration <strong>and</strong> networking, bringing together research, surveillance<br />

<strong>and</strong> clinical <strong>and</strong> public health practices, with the ultimate goal of enhancing the quality of surveillance data <strong>and</strong><br />

exp<strong>and</strong>ing our underst<strong>and</strong>ing of congenital anomalies.<br />

Critical Care Research Network (www.criticalcareresearch.net) Network’s mission is to improve patient care <strong>and</strong> resource utilization through the rigorous evaluation of health delivery<br />

systems. Encompasses a broad spectrum of 9 teaching hospitals, 24 community hospitals, <strong>and</strong> many industry <strong>and</strong><br />

government partners across Canada.<br />

International<br />

Diabetes TrialNet (www.diabetestrialnet.org) International network of researchers who are exploring ways to prevent, delay <strong>and</strong> reverse the progression of type 1<br />

diabetes.<br />

Metabolic Diseases networks (various) N/A<br />

Pediatric Inflammatory Bowel Disease Collaborative Research N/A<br />

Group/ Registry (no URL)


292<br />

BRITISH COLUMBIA<br />

APPENDIX 11. INDEPENDENT CLINICAL TRIALS SERVICE COMPANIES<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

ASKA Research<br />

www.askaresearch.com<br />

http://askaresearch.trainingcampus.net<br />

Corporate Headquarters:<br />

#410 - 1385 West 8th Ave<br />

Vancouver, B.C. V6H 3V9<br />

Tel : 604-736-3166<br />

Fax: 604-736-1936<br />

info@askaresearch.com<br />

Contact: Valerie Willetts<br />

valwilletts@askaresearch.com<br />

Contact: Les Gee<br />

lesgee@askaresearch.com<br />

Provides a full range of multi-centre clinical trial management<br />

<strong>and</strong> monitoring services from project conception<br />

to marketing approval, from Phase I to IV in all areas of<br />

Pharma. No data management or processing.<br />

• <strong>Clinical</strong> Development Planning services include assessment,<br />

analysis <strong>and</strong> preparation of risk-benefit evaluations<br />

that assist you in developing business strategies.<br />

• Regulatory Services cover the preparation <strong>and</strong> submission<br />

of dossiers to obtain country-specific approvals to conduct<br />

clinical trials.<br />

• Project Management directing <strong>and</strong> site selection <strong>and</strong> ICF<br />

<strong>and</strong> CRF design. Site management <strong>and</strong> operations.<br />

Monitoring/<strong>Clinical</strong> Research Associates (CRAs): regionally<br />

based network of CRAs available for monitoring in any<br />

region in Canada. Monitoring services are also accessible<br />

through our collaborative partner organizations <strong>and</strong> our<br />

CRO alliance partners in the United States, Australia, Europe<br />

<strong>and</strong> the Asia-Pacific region. Monitoring services encompass<br />

all quality control aspects of single or multi-centre clinical<br />

research trials.<br />

ASKA services also include:<br />

• <strong>Clinical</strong> Research Meeting Planning - facilitation of <strong>Clinical</strong><br />

Research meetings.<br />

• Star Products - custom products <strong>and</strong> tools for clinical<br />

research program activities<br />

• Online Training - provider of reference manuals from RAN<br />

Institute.<br />

• Online GCP training for Sponsors <strong>and</strong> Monitors<br />

• Online GCP training for Investigators <strong>and</strong> Co-ordinators.<br />

• St<strong>and</strong>ard Operating Procedures development<br />

• Implementation of FDA, Health Canada & ICH/GCP<br />

Guidelines.<br />

SME with Strategic<br />

operational partnering<br />

Strategic links<br />

worldwide: formal<br />

operational links<br />

through partnering<br />

organisations in:<br />

• Europe/UK<br />

(Harrison <strong>Clinical</strong><br />

Research)<br />

• India<br />

• Australia (<strong>Clinical</strong><br />

Network Services)<br />

• US<br />

• Japan / Tokyo<br />

(ASKLEP)<br />

Staff of 8 persons<br />

Vancouver based<br />

Types of Clients Regulatory<br />

Qualifications<br />

Large Pharma,<br />

SMEs, Hospitals,<br />

Institutions,<br />

University Med<br />

Schools, <strong>and</strong><br />

small operations<br />

requiring<br />

CT operations<br />

services<br />

ASKA operates<br />

to ICH <strong>and</strong> GCP<br />

ICH/GCP <strong>and</strong><br />

Customized<br />

Training - ACRP<br />

Credentialed<br />

<strong>Clinical</strong> Research<br />

Trainer<br />

(CCRT) <strong>and</strong> a<br />

pool of experts<br />

Quality<br />

Assurance<br />

- compliance<br />

with ICH/GCP<br />

<strong>and</strong> applicable<br />

regulatory<br />

requirements;<br />

documented<br />

<strong>and</strong> reported<br />

accordingly.<br />

Research<br />

Professionals<br />

Network (RPN)<br />

includes experienced<br />

monitors<br />

<strong>and</strong> auditors


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

293<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

B.C. Biomedical Laboratories<br />

Ltd.<br />

www.bcbio.com<br />

B.C. Community Oncology<br />

Trialists (BCCOT)<br />

No URL<br />

7455 - 130th Street, Surrey,<br />

B.C. V3W 1H8<br />

Contact for clinical trials:<br />

Tel: 604-507-5091 or 604-<br />

507-5170<br />

Fax: 604-507-5212<br />

BusinessAccounts@bcbiomedical.com<br />

Contact: Ryan Tkachuk,<br />

Research Coordinator. B.C.<br />

Community Oncology Trialists<br />

705-4980 Kingsway,<br />

Burnaby B.C., V5H 4K7<br />

Tel: 604-836-5340<br />

tkservices@shaw.ca<br />

Director: Wendy Lam<br />

The largest physician-owned (Dr. C.J. Coady Associates)<br />

<strong>and</strong> operated laboratory in B.C. Its medical diagnostic<br />

services are an integral part of the B.C. health care system,<br />

with more than 1.9 million patients visiting one of its 45<br />

Patient Service Centres throughout the Lower Mainl<strong>and</strong>. B.C.<br />

Biomed also provides collection, management, <strong>and</strong> testing<br />

services for the following:<br />

• <strong>Clinical</strong> <strong>Trials</strong><br />

• Scientific Research<br />

• Special Studies<br />

• Pre-employment Testing<br />

• Insurance Kits<br />

• Toxicology<br />

• Occupational Testing<br />

• Wellness Testing<br />

Independent research company formed by oncologists that<br />

work outside the BCCA in community oncology sites.<br />

B.C. COT conducts phase II-IV clinical research studies out of<br />

their private offices using a central ethics board, in particular<br />

IRB Services. These private offices are located in Richmond,<br />

Burnaby <strong>and</strong> North Vancouver B.C.<br />

To date B.C. COT has conducted 9 successful clinical trials<br />

using this infrastructure, <strong>and</strong> continues to look for new<br />

<strong>and</strong> interesting protocols in the fields of hematology <strong>and</strong><br />

oncology.<br />

B.C. COT is also extensively involved in continuing medical<br />

education in the community.<br />

A partnership<br />

comprised of<br />

over 40 leading<br />

practitioners in all<br />

disciplines of laboratory<br />

medicine<br />

A research study<br />

will be set up at a<br />

one of the office<br />

sites <strong>and</strong> satellite<br />

sites will be<br />

added if multiple<br />

investigators are<br />

interested.<br />

Staff include:<br />

• Members of<br />

<strong>Clinical</strong> Research<br />

Professionals of<br />

B.C (CRPBC)<br />

• TDG/IATA<br />

trained staff<br />

for local <strong>and</strong><br />

international<br />

transport of<br />

specimens<br />

Consists of 7<br />

oncologists <strong>and</strong><br />

a clinical trials<br />

coordinator<br />

Members: Dr.<br />

Paul Klimo, Dr.<br />

John Yun, Dr. Michael<br />

Noble, Dr.<br />

David Stuart, Dr.<br />

Sasha Smiljanic,<br />

Dr. Simon Yu<br />

Types of Clients Regulatory<br />

Qualifications<br />

• Pharmaceutical<br />

companies<br />

• Physicians<br />

• <strong>Clinical</strong><br />

Research Professionals<br />

• Canadian, US,<br />

International<br />

organizations<br />

Accredited by<br />

the Diagnostic<br />

Accreditation<br />

Program of the<br />

B.C. College<br />

of Physicians<br />

<strong>and</strong> Surgeons;<br />

accredited<br />

laboratory with<br />

the College<br />

of American<br />

Pathologists<br />

Large <strong>and</strong> small<br />

pharma/biotech<br />

B.C. COT<br />

conducts its<br />

clinical research<br />

projects in accordance<br />

with<br />

ICH/GCP.


294<br />

BRITISH COLUMBIA<br />

APPENDIX 11. Independent <strong>Clinical</strong> <strong>Trials</strong> Service Companies (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

BRI Biopharmaceutical<br />

Research Inc.<br />

www.bripharm.com<br />

101 - 8898 Heather Street<br />

Vancouver, B.C. V6P 3S8<br />

President<br />

David Kwok<br />

dkwok@bripharm.com<br />

Tel : 604-432-9237<br />

Fax: 604-432-9239<br />

Contract research organization that provides research services<br />

to the pharmaceutical, nutraceutical <strong>and</strong> biotechnology<br />

industries in Canada, USA <strong>and</strong> Asia.<br />

Provides specialized <strong>and</strong> integrated preclinical drug development<br />

contract research services for worldwide regulatory<br />

submissions.<br />

BRI Drug Development Services include:<br />

Lead Drug C<strong>and</strong>idate ADMET Selection:<br />

• Pharmacokinetics <strong>and</strong> Distribution Screening<br />

• Biological half-life screening<br />

• Serum protein binding using equilibrium dialysis In-vitro<br />

red blood cell distribution<br />

• Half-life modification<br />

Oral Bioavailability Screening:<br />

• Oral formulation bioavailability<br />

• First-pass hepatic <strong>and</strong> gut metabolism screening<br />

• Metabolism Screening<br />

• In-vitro CYP450 metabolic stability screening<br />

• LC/MS <strong>and</strong> LC/MS/MS metabolite profile<br />

• Toxicology/Safety Screening<br />

• Genotoxicity profiling<br />

• Acute MTD study in mice or rat<br />

• Chemistry Screening<br />

• Aqueous <strong>and</strong> solvent solubility<br />

• Solution pH profile stability<br />

Additional services:<br />

• Drug Chemistry Patents<br />

• In-Vitro / In-Vivo Metabolism<br />

• <strong>Preclinical</strong> Development<br />

• CMC Studies<br />

• Formulation Development<br />

• API <strong>and</strong> <strong>Clinical</strong> Product Storage Stability<br />

• <strong>Clinical</strong> Phase I/II Bioanalytical Assays<br />

• <strong>Clinical</strong> Sample Management<br />

• Natural Health Product / Dietary Supplement Development<br />

• Regulatory Compliance<br />

Types of Clients Regulatory<br />

Qualifications<br />

Large Pharma,<br />

SMEs, Hospitals,<br />

Institutions,<br />

University Med<br />

schools, <strong>and</strong><br />

small operations<br />

requiring<br />

CT operations<br />

services<br />

GMP / GLP<br />

Establishment<br />

License<br />

CNSC Nuclear<br />

Substance<br />

License<br />

BRI has established<br />

st<strong>and</strong>ard<br />

ADMET study<br />

protocols in<br />

collaboration<br />

with specialized<br />

animal facilities


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

295<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

Canadian Western Institutional<br />

Review Board (WIRB)<br />

www.wirb.com<br />

Can-Med <strong>Clinical</strong> Research<br />

Inc.<br />

www.can-med.ca<br />

Suite 400-601 West Broadway<br />

Vancouver, B.C. V5Z 4C2<br />

Board Liaison, WIRB Canada<br />

Tel : 604 872-5030<br />

Fax 604 872-5032<br />

Client Services<br />

Tel : 800-562-4789<br />

clientservices@wirb.com<br />

Chair/President of REB: John<br />

McNeill PhD<br />

Contact: Yi He<br />

yhe@wirb.com<br />

330-1641 Hillside Avenue,<br />

Victoria, B.C. V8T 5G1<br />

Tel: 250-370-2606<br />

Fax: 250-370-2604<br />

Contact: Cindy Trytten<br />

cindy.trytten@can-med.ca<br />

Contact: Dr. Peter Pommerville<br />

peter.pommerville@can-med.<br />

ca<br />

Research Ethics Board for <strong>Clinical</strong> Research Studies in Canada<br />

Provides independent IRB services, often to industrysponsored<br />

national multi-centre <strong>and</strong> international clinical<br />

trials for Biomedical, Behavioural, Social <strong>Sciences</strong> studies.<br />

Able to provide a broad range of services with the flexibility<br />

to meet individual needs while maintaining full regulatory<br />

compliance.<br />

WIRB provides review services for more than 100 institutions<br />

including academic centres, hospitals, networks <strong>and</strong><br />

in-house biotech research, as well as for individual investigators<br />

in all 50 states <strong>and</strong> internationally. WIRB has worked<br />

with all major pharmaceutical <strong>and</strong> device manufacturers,<br />

<strong>and</strong> CROs; the biotech industry; <strong>and</strong> is actively developing<br />

the internet links for secure, fully-electronic submissions.<br />

WIRB Services:<br />

• IRB Review<br />

• Training<br />

• Institutional Biosafety Committee Services (IBCS)<br />

• Data <strong>and</strong> Safety Monitoring Services<br />

• Consultations<br />

• Exemption Determinations<br />

Specializes in clinical trials in urology (including prostate<br />

<strong>and</strong> bladder cancer) on Vancouver Isl<strong>and</strong>. The largest<br />

urology-focused clinical trial site in Western Canada. Incorporated<br />

in 2000, the facility includes 5 private examination<br />

rooms used for conducting the informed consent process,<br />

discussions with patients <strong>and</strong> performing study related<br />

assessments, a secure investigational product storage room<br />

<strong>and</strong> secure refrigerators, a secure, locked filing room that<br />

houses case report forms <strong>and</strong> source documents for current<br />

studies, <strong>and</strong> private rooms for monitors <strong>and</strong> auditors.<br />

Provides support services to other Investigational Sites,<br />

including budget <strong>and</strong> contract development, SOP templates<br />

<strong>and</strong> on-site training for research coordinators.<br />

Committee:<br />

Independent (nonaffiliated)<br />

For-profit organization<br />

based in the<br />

US, with representatives<br />

located in<br />

Vancouver, B.C.<br />

Located in Victoria<br />

B.C.<br />

Dr Peter Pommerville<br />

(FRCS(C))<br />

is the Founder<br />

<strong>and</strong> Director of<br />

Research.<br />

The Board meets<br />

every two weeks<br />

in its office located<br />

in Vancouver<br />

B.C.; supported<br />

by staff at WIRB<br />

headquarters in<br />

Olympia Washington.<br />

7 staff: Director<br />

of Research,<br />

Site Manager, 4<br />

research coordinators,<br />

I research<br />

assistant<br />

Types of Clients Regulatory<br />

Qualifications<br />

Large Pharma,<br />

SMEs, Hospitals,<br />

Institutions,<br />

University Med<br />

schools, <strong>and</strong><br />

small operations<br />

requiring CT REB<br />

services<br />

Reviews in accordance<br />

with:<br />

Health Canada<br />

Division 5,<br />

the Tri Council<br />

Policy Statement<br />

ICH GCP E6 <strong>and</strong><br />

US CFR Title 21<br />

Parts 50 <strong>and</strong> 56<br />

CFR Title 45<br />

Part 46.<br />

Large <strong>and</strong> small<br />

pharma/biotech,<br />

CROs<br />

<strong>Trials</strong> comply<br />

with GCP <strong>and</strong><br />

applicable<br />

federal (Canada<br />

<strong>and</strong> US) regulations


296<br />

BRITISH COLUMBIA<br />

APPENDIX 11. Independent <strong>Clinical</strong> <strong>Trials</strong> Service Companies (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

CanTest Ltd.<br />

(Acquired by Maxxam Analytics<br />

October 23rd, 2009)<br />

www.cantest.com<br />

CanTest Head Office<br />

4606 Canada Way ,<br />

Burnaby B.C. V5G 1K5<br />

Tel: 604-734- 7276<br />

Tel : 800-665- 8566<br />

Fax: 604- 731-2386<br />

A leading analytical <strong>and</strong> testing laboratory in Canada,<br />

providing analytical <strong>and</strong> testing to measure <strong>and</strong> monitor<br />

substances that impact environment <strong>and</strong> health. Offers<br />

integrated analytical <strong>and</strong> specialized testing in support of<br />

industries <strong>and</strong> regulators assessing environmental quality,<br />

pharmaceutical/biotechnology efficacy, food quality, <strong>and</strong><br />

drug residues.<br />

CanTest provides:<br />

• Pharmaceutical testing including GLP <strong>and</strong> non-GLP<br />

analytical testing for all stages of the drug development<br />

process, from preclinical development to Phase IV clinical<br />

trials<br />

• Analyses of pesticides, heavy metals, microbiology <strong>and</strong><br />

active ingredients (potency) in NHPs, as well as shelf life<br />

testing, which will help in determining the safety <strong>and</strong><br />

efficacy requirements of the product for obtaining product<br />

licensing.<br />

• High-throughput screening of potential drug c<strong>and</strong>idates,<br />

using high efficiency <strong>and</strong> high quality ADME profiling. The<br />

laboratory offers in vitro ADME assays to accelerate the<br />

drug discovery process <strong>and</strong> facilitate success in producing<br />

optimal <strong>and</strong> viable clinical c<strong>and</strong>idates.<br />

CanTest has major,<br />

Canadian <strong>and</strong> N<br />

American operations,<br />

with 10,000<br />

m2 analytical <strong>and</strong><br />

testing laboratory<br />

facilities.<br />

Located in Burnaby<br />

B.C.; with sales offices<br />

in Vancouver,<br />

Victoria <strong>and</strong><br />

Kelowna B.C.; Winnipeg,<br />

Manitoba<br />

<strong>and</strong> Boston, Massachusetts.<br />

CanTest employs<br />

350 scientists,<br />

technologists <strong>and</strong><br />

support staff<br />

Maxxam is<br />

Canada’s largest<br />

independent analytical<br />

laboratory<br />

business, with<br />

1,500 employees<br />

across Canada<br />

at 26 locations,<br />

including 14 labs.<br />

Types of Clients Regulatory<br />

Qualifications<br />

Primarily serves<br />

Canadian <strong>and</strong><br />

North American<br />

Clients; with<br />

international<br />

capabilities,<br />

including Large<br />

Pharma, SMEs,<br />

Hospitals,<br />

Institutions,<br />

University Med<br />

schools, <strong>and</strong><br />

small operations<br />

requiring<br />

CT operations<br />

services<br />

Provides<br />

pharmaceutical<br />

testing<br />

including GLP<br />

<strong>and</strong> non-GLP<br />

analytical testing<br />

<strong>and</strong> GMP<br />

Pharmaceutical<br />

Analysis


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

297<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

Discovery<br />

No URL<br />

Isl<strong>and</strong> Medical Laboratories,<br />

4489 Viewmont Avenue,<br />

Victoria, B.C. V8Z 5K8.<br />

Tel: 250-370-8437<br />

gordon.hoag@viha.ca<br />

Testing <strong>and</strong> services for clinical trial <strong>and</strong> pharmaceutical<br />

evaluation:<br />

• Method Development & Validation<br />

• Early drug discovery<br />

• Toxicokinetic studies in animals<br />

• Pharmacokinetic studies<br />

• Bioequivalence studies<br />

• GLP Bioanalysis<br />

• GMP Pharmaceutical Analysis<br />

• Elemental Analysis by ICP-MS<br />

• Metal Testing by ICP-MS, LC-ICPMS, GC-ICPMS, ICP-OES<br />

• Leachables <strong>and</strong> extractables<br />

• Material science testing<br />

• Drug Discovery Support<br />

• Pharmacokinetic & Bioequivalence Studies<br />

• Forensic Equine Drug Testing<br />

• Drug-drug interaction <strong>and</strong> therapeutic drug monitoring<br />

• <strong>Clinical</strong> support services<br />

• Environmental testing<br />

• Food residue analysis<br />

• Food labelling testing<br />

• Industrial hygiene<br />

• Microbiology<br />

• Physical-chemical characterization of new chemicals<br />

• GLP Ecotoxicology/ EcoFATE<br />

• Pharmaceuticals in the environment<br />

• Acid-rock drainage<br />

N/A Located in Victoria<br />

B.C.<br />

Types of Clients Regulatory<br />

Qualifications<br />

N/A N/A N/A


298<br />

BRITISH COLUMBIA<br />

APPENDIX 11. Independent <strong>Clinical</strong> <strong>Trials</strong> Service Companies (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

Fraser <strong>Clinical</strong> Trial Inc.<br />

No URL<br />

106-245 Columbia Street<br />

East, New Westminster, B.C.<br />

V3L 3W4<br />

Tel: 604-521-4500<br />

Contact: Sharon Stevens<br />

sstevens@fct05.com<br />

Independent clinical trials company, conducting studies in<br />

cardiology, GI, <strong>and</strong> oncology.<br />

Located in New<br />

Westminster B.C.<br />

Types of Clients Regulatory<br />

Qualifications<br />

N/A N/A N/A<br />

Global Client Partners<br />

Consulting Inc.<br />

www.gcpconsultants.com<br />

Interior <strong>Clinical</strong> Research<br />

Consultants Ltd<br />

No URL<br />

Unit 6 - 10460 No. 3 Road,<br />

Richmond, B.C. V7A 4W5<br />

Brent Cherban, Manager Business<br />

Development<br />

Tel: 604-222-9022<br />

Cell: 604-551-5372<br />

brent@gcpconsultants.com<br />

2309 Abbott Street, Kelowna,<br />

B.C. V1Y 1E4<br />

Tel: 250-862-9777<br />

Contact: Michele Mantle.<br />

Manager<br />

icrcl@telus.net<br />

Research Services Organization that provides services for<br />

investigator-initiated <strong>and</strong> biopharmaceutical studies, as well<br />

as medical writing <strong>and</strong> training. Services include:<br />

• Protocol Development<br />

• Informed Consent Form templates<br />

• Grant Writing<br />

• Development of St<strong>and</strong>ard Operating Procedures (SOPs)<br />

• Study Operations, Lab <strong>and</strong> Pharmacy Manual<br />

• Project/Trial Management<br />

• Monitoring<br />

• Data Management<br />

• Regulatory Affairs<br />

• Site Personnel Educational Materials <strong>and</strong> Source Documents<br />

• Final Study Reports<br />

• Communications<br />

• Training<br />

- ICH: Good <strong>Clinical</strong> Practice Guidelines<br />

- Code of Federal Regulations<br />

- Investigator <strong>and</strong> Coordinator Meetings<br />

- SOPs<br />

Sets-up <strong>and</strong> manages mainly Phases II <strong>and</strong> III clinical<br />

trials in all areas of nephrology, cardiology, respirology,<br />

orthopedics, general surgery, <strong>and</strong> critical care. . Conducts<br />

the majority of in- <strong>and</strong> out-patient trials at Kelowna General<br />

Hospital <strong>and</strong> out-patient trials with local physicians.<br />

Located in New<br />

Richmond B.C.<br />

Established in<br />

1995 at Kelowna<br />

General Hospital<br />

<strong>and</strong> then spun out<br />

as an independent<br />

company<br />

Full time administrative<br />

head<br />

office staff; but<br />

primarily contract<br />

staff to ensure<br />

low cost services<br />

to the client<br />

4 research<br />

nurses/ coordinators<br />

2 research assistants<br />

1 manager<br />

Health authorities,<br />

biotech<br />

companies<br />

Physicians, biotech<br />

<strong>and</strong> pharma<br />

companies<br />

<strong>Clinical</strong> research<br />

projects conducted<br />

in accordance<br />

with<br />

Health Canada,<br />

FDA, <strong>and</strong> NIH<br />

regulations <strong>and</strong><br />

guidelines.<br />

All studies<br />

compliant with<br />

Health Canada,<br />

FDA, <strong>and</strong> ICH<br />

regulations <strong>and</strong><br />

guidelines


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

299<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

<strong>Life</strong>Labs Medical Laboratory<br />

Services<br />

www.lifelabs.com/<br />

<strong>Life</strong>Labs_BC/<br />

Liver <strong>and</strong> Intestinal Research<br />

Centre (LAIR)<br />

www.laircentre.com<br />

MDIT Innovations Inc.<br />

www.mditinnovations.com/<br />

Medical Arts Health Research<br />

Group<br />

www.healthresearch.ca<br />

<strong>Clinical</strong> trials services in<br />

B.C.: Burnaby Reference<br />

Laboratory, 3680 Gilmore Way,<br />

Burnaby, B.C. V5G 4V8<br />

Tel: 604-431-5005.<br />

Contract.Service@<strong>Life</strong>Labs.<br />

com<br />

Dr.Frank H. Anderson<br />

305 - 750 West Broadway<br />

Vancouver, B.C. V5Z 1H2<br />

Tel: 604-876-5122<br />

Fax: 604-484-3026<br />

info@laircentre.com<br />

1199 Main Street, Vancouver,<br />

B.C. V6A 4B6<br />

Tel: 604 638 9870<br />

Fax: 604 638 6076<br />

info@adeptclinic.com<br />

Contact: Alex Marcu<br />

Tel: 604-638-9872<br />

amarcu@mditinnovations.<br />

com<br />

Main office:<br />

#3 – 626 Main St., Penticton,<br />

B.C. V2A 5C8<br />

Tel: 250-493-7286<br />

Fax: 250-493-728.<br />

info@pctnetworks.com<br />

Provides clinical laboratory testing services across Canada<br />

– more than 50 million laboratory tests to over 10 million<br />

patients <strong>and</strong> nearly 20,000 physicians. Has 80 service centres<br />

across B.C. Offers specialized services in B.C. for clinical trials.<br />

Provides clinical expertise <strong>and</strong> conducts Phases I, II, <strong>and</strong> III<br />

clinical trials in patients with liver <strong>and</strong> inflammatory bowel<br />

disease. Run by Frank Anderson, whose details can be found<br />

in Appendix 6.<br />

Provides clinical management systems (software) for the<br />

medical industry. Applicable to regular patient treatment/<br />

management, as well as facilitating medical research<br />

through independent or sponsored clinical trials.<br />

A clinical research organization that conducts Phases II, III,<br />

<strong>and</strong> IV clinical trials in the Okanagan Valley. Covers chronic<br />

diseases in most therapeutic areas, e.g., arthritis, stroke<br />

prevention, Alzheimer’s, pain, smoking cessation, diabetes,<br />

migraine<br />

National company<br />

with significant<br />

operations in B.C.<br />

Located in Vancouver.<br />

Located in Vancouver.<br />

3 offices, one each<br />

in Penticton, Kelowna,<br />

<strong>and</strong> Vernon<br />

N/A Physicians, biotech<br />

<strong>and</strong> pharma<br />

companies<br />

4 doctors, 6 nurses,<br />

a dietician, 2<br />

psychologists, 1<br />

alternative medicine<br />

practitioner<br />

Types of Clients Regulatory<br />

Qualifications<br />

N/A N/A<br />

N/A Physicians N/A<br />

N/A Pharma N/A<br />

Accredited by<br />

the Diagnostic<br />

Accreditation<br />

Program of the<br />

B.C. College of<br />

Physicians <strong>and</strong><br />

Surgeons for<br />

the Burnaby<br />

<strong>and</strong> Victoria<br />

References<br />

Labs.


300<br />

BRITISH COLUMBIA<br />

APPENDIX 11. Independent <strong>Clinical</strong> <strong>Trials</strong> Service Companies (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

Nanaimo Research Institute<br />

www.nri-nanaimo.ca<br />

515 B Campbell Street,<br />

Nanaimo, B.C. V9R 3G9<br />

Tel: 250-714-1157; Fax: 250-<br />

714-1163<br />

nri@telus.net<br />

Participates in Phase III <strong>and</strong> Phase IV national <strong>and</strong> international<br />

clinical research in cardiology/ cardiovascular diseases,<br />

orthopedic, respiratory, diabetes <strong>and</strong> other metabolic<br />

disorders, <strong>and</strong> palliative care. <strong>Clinical</strong> research in both in<br />

hospital <strong>and</strong> outpatient trials. Established in 1997 under the<br />

directorship of Dr. Lawrence Winkler <strong>and</strong> Dr. Kevin Lai.<br />

Independent organization<br />

located in<br />

Nanaimo B.C.<br />

8 staff: 2 physicians<br />

(internal<br />

medicine),<br />

5 research nurses,<br />

1 research respiratory<br />

therapist<br />

Okanagan <strong>Clinical</strong> <strong>Trials</strong><br />

(OCT)<br />

www.oktrials.ca<br />

204-1353 Ellis St<br />

Kelowna, B.C., V1Y 1Z9<br />

Tel: 250-862-8141<br />

Fax: 250-862- 8130<br />

Paul Latimer<br />

dr@oktrials.ca<br />

Sally Godsell<br />

OCT conducts clinical trials on an out-patient basis for the<br />

pharmaceutical industry (primarily large pharma). Phase<br />

II - IV trials in a variety of therapeutic areas.<br />

Medical specialists, research co-ordinators <strong>and</strong> staff are<br />

equipped to undertake trials in psychiatry, gastroenterology,<br />

gynecology, urology, cardiology, neurology, pediatrics,<br />

ophthalmology.<br />

Studies conducted<br />

as out-patient<br />

visits from the<br />

Okanagan region<br />

of B.C.<br />

Employees 8<br />

persons located<br />

in Kelowna<br />

2 investigators<br />

3 Study coordinators<br />

Types of Clients Regulatory<br />

Qualifications<br />

Hospital;<br />

Clinic outpatients<br />

Predominantly<br />

in North America<br />

<strong>and</strong> Canada;<br />

also Japan<br />

<strong>and</strong> Europe.<br />

Include Pharma<br />

Companies,<br />

SMEs, Hospitals,<br />

<strong>and</strong> Institutions<br />

requiring CT<br />

operations <strong>and</strong><br />

services<br />

Conforms to<br />

Good <strong>Clinical</strong><br />

Practice/<br />

International<br />

Conference on<br />

Harmonization<br />

ICH/GCP trained<br />

research staff<br />

Quality Assurance<br />

Compliance<br />

with ICH/GCP,<br />

local <strong>and</strong> central<br />

regulatory<br />

requirements<br />

OCT services<br />

comply with:<br />

GCP


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

301<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

Oxford Outcomes<br />

www.oxfordoutcomes.com<br />

Pacific Nuclear Medicine Inc.<br />

(PNM)<br />

No URL<br />

Vancouver office:<br />

450 - 688 W. Hastings St.,<br />

Vancouver B.C. V6B 1P1<br />

Tel: 604-331-8414<br />

Fax: 604-331-8446<br />

Health economics: jennifer.<br />

sambrook@oxfordoutcomes.<br />

com<br />

Epidemiology: shelagh.<br />

szabo@oxfordoutcomes.com<br />

Lions Gate Hospital Foundation<br />

231 East 15th Street<br />

North Vancouver<br />

B.C. V7L 2L7<br />

Head of the Division of<br />

Nuclear Medicine:<br />

Dr. Philip Cohen<br />

Tel : 604-984-5954<br />

cohen@triumf.ca<br />

International health outcomes consultancy with offices in<br />

the UK (Oxford), Canada (Vancouver <strong>and</strong> Toronto) <strong>and</strong> the<br />

US (Bethesda, MD <strong>and</strong> Morristown, NJ). Provides a broad<br />

spectrum of specialist services in:<br />

• patient reported outcomes research<br />

• health economics<br />

• epidemiology<br />

• infectious disease research<br />

• translation <strong>and</strong> linguistic validation.<br />

Supports the drug development lifecycle through early<br />

stage development <strong>and</strong> investment, market access, reimbursement,<br />

regulatory approvals, peri-approval <strong>and</strong> marketing<br />

development process.<br />

Located at Lions Gate Hospital; specializes in undertaking<br />

clinical trials for new biopharmaceuticals which are<br />

labeled with radioactive tracers for both radiodiagnosis <strong>and</strong><br />

radiotherapy.<br />

Collaborations with several research groups at the UBC <strong>and</strong><br />

SFU as well as Vancouver area teaching hospitals.<br />

Areas of current interest involve single photon studies<br />

for absolute quantitation, multiple simultaneous tracer<br />

studies, <strong>and</strong> dynamic SPECT for groups wishing to introduce<br />

new tracers. Collaborations possible through <strong>Life</strong> <strong>Sciences</strong><br />

program at TRIUMF for novel radionuclides.<br />

Consulting services<br />

led by a strong<br />

group of consultants<br />

<strong>and</strong> opinion<br />

leaders from health<br />

economics <strong>and</strong><br />

outcomes research<br />

Hospital<br />

Department that<br />

offers clinical trial<br />

development of<br />

new radiotracer/<br />

radiotherapeutic<br />

pharmaceuticals.<br />

Offers services<br />

primarily to clients<br />

in North America<br />

<strong>and</strong> Canada<br />

At least 2 people<br />

located in Vancouver<br />

2 people located<br />

in N. Vancouver<br />

PerCuro <strong>Clinical</strong> Research<br />

Ltd.<br />

No URL<br />

200-1105 P<strong>and</strong>ora Avenue,<br />

Victoria, B.C. V8V 3P9<br />

Tel: 250-382-6270<br />

Fax: 250-382-6273<br />

Contact: Leeanna Bulinckx –<br />

President. leeanna@percuro.<br />

net<br />

Conducts out patient clinical trials for the pharmaceutical<br />

industry in the areas of rheumatology, dermatology, gastroenterology<br />

<strong>and</strong> infectious diseases (in particular Hepatitis<br />

C). Services include clinical trial management, budget<br />

negotiation, <strong>and</strong> regulatory management. <strong>Trials</strong> undertaken<br />

to date have been Phases II-IV.<br />

Principal Investigators are specialists in their field. Research<br />

coordinators are all Registered Nurses with most holding<br />

their baccalaureate degree. Lab draws <strong>and</strong> processing are<br />

performed on site. All nurse coordinators are certified in IV<br />

therapy with a three chair research infusion clinic as part of<br />

the site.<br />

All studies<br />

conducted on an<br />

outpatient basis.<br />

PerCuro services<br />

the Victoria, Gulf<br />

Isl<strong>and</strong>s, <strong>and</strong> South<br />

Vancouver Isl<strong>and</strong><br />

area of B.C..<br />

11 on staff: 4<br />

study coordinators;<br />

5 investigators<br />

located in<br />

Victoria, B.C.<br />

Types of Clients Regulatory<br />

Qualifications<br />

Pharma, biotech,<br />

others<br />

N/A<br />

Companies, Hospitals,<br />

Institutions,<br />

University<br />

Med schools, <strong>and</strong><br />

small operations<br />

requiring<br />

radiotherapeutic<br />

clinical trial<br />

services<br />

PNM operates<br />

to:<br />

GCP<br />

Pharmaceutical<br />

companies from<br />

US, Europe <strong>and</strong><br />

Canada<br />

Operates to GCP


302<br />

BRITISH COLUMBIA<br />

APPENDIX 11. Independent <strong>Clinical</strong> <strong>Trials</strong> Service Companies (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

PRA International - Victoria<br />

www.prainternational.com<br />

PRA International - Victoria<br />

300-655 Tyee Road<br />

Victoria B.C. V9A 6X5<br />

Tel : 250-483-4400<br />

Fax: 250-483-4401<br />

Senior Vice President<br />

Greg Gurasci<br />

Business contact<br />

Amelia Orr<br />

-<br />

PRA<br />

Corporate<br />

Headquarters<br />

4130 Park Lake<br />

Avenue - Suite 400 R<br />

aleigh<br />

North Carolina<br />

27612<br />

Tel : 919<br />

-786-8200<br />

Large multi-national multi-capability CRO providing International<br />

services through all phases of clinical development<br />

(Phase I – IV) with facilities in Victoria B.C..<br />

Services world-wide to pharmaceutical <strong>and</strong> biotech companies<br />

in the US, Europe, <strong>and</strong> Japan. More than 100 complex<br />

studies <strong>and</strong> over 200 bioanalytical studies yearly for studies<br />

recruiting healthy volunteers or special patient populations.<br />

Study populations include: healthy volunteers, special populations,<br />

<strong>and</strong> populations with specific medical conditions.<br />

Has specialities in early Phase I <strong>and</strong> II clinical trials.<br />

Services include:<br />

• Feasibility assessments<br />

• Protocol design<br />

• IMPD <strong>and</strong> CRF development<br />

• Recruitment<br />

• Data management<br />

• Pharmacy services, including manufacturing<br />

• <strong>Clinical</strong> conduct<br />

• Bioanalysis (PK/PD) including biomarkers<br />

• Data analysis<br />

• <strong>Clinical</strong> study reports<br />

• Medical writing<br />

• Regulatory support<br />

Phase II <strong>and</strong> III Studies: PRA assists in Product registration<br />

across a range of therapeutic areas, including:<br />

• Oncology<br />

• CNS<br />

• Respiratory/allergy<br />

• Gastroenterology<br />

• Immunology<br />

Phase II / III Services include:<br />

• Regulatory Affairs.<br />

• Project management - Project Start-up<br />

• <strong>Clinical</strong> Site Monitoring Services<br />

• Event reporting procedures<br />

• Support structures for clinical teams.<br />

Data management<br />

facilities <strong>and</strong><br />

services located in<br />

Victoria B.C.<br />

PRA clinical facilities<br />

are located in<br />

the United States,<br />

the Netherl<strong>and</strong>s<br />

<strong>and</strong> Central Europe.<br />

A bioanalytical<br />

facility is located in<br />

Netherl<strong>and</strong>s.<br />

90+ Personnel<br />

located at the<br />

Victoria office<br />

500 specialists in<br />

seven countries<br />

International<br />

Company with<br />

teams worldwide<br />

<strong>and</strong> offices in:<br />

• USA<br />

• Mexico<br />

• S America<br />

• UK<br />

• Netherl<strong>and</strong>s<br />

• Germany<br />

• Hungary<br />

• Belgium<br />

• France<br />

• Spain<br />

• Pol<strong>and</strong><br />

• Russia<br />

• S Africa<br />

• Korea<br />

• Hong Kong<br />

• China<br />

• Australia<br />

• India<br />

Types of Clients Regulatory<br />

Qualifications<br />

Large Pharma,<br />

SMEs Hospitals<br />

Institutions<br />

University Med<br />

schools <strong>and</strong><br />

small operations<br />

requiring<br />

CT operations<br />

services<br />

PRA services<br />

comply with:<br />

GCP<br />

GLP<br />

cGMP<br />

ICH


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

303<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

ProHealth <strong>Clinical</strong> Research<br />

Centre<br />

www.prohealthcr.ca<br />

Syreon Corporation<br />

www.syreon.com<br />

600-1285 West Broadway<br />

Vancouver, B.C.<br />

V6H 3X8<br />

Tel: 604-263-3644<br />

Fax: 604-263-3744<br />

TOLL FREE: 1-866-226-6143.<br />

prohealth@prohealthcr.ca<br />

260 - 1401 West 8th Avenue<br />

Vancouver, B.C.<br />

V6H 1C9<br />

Director, Business Development<br />

- Brendan Keown<br />

brendan.keown@syreon.com<br />

Head of Project Management:<br />

Rohinish.Gunadasa@syreon.<br />

com<br />

Tel: 604-676-5900<br />

Fax : 604-676-5911<br />

info@syreon.com<br />

Specializes in clinical research in the areas of men’s health,<br />

postmenopausal women’s health, metabolic bone diseases<br />

(osteoporosis) <strong>and</strong> endocrine disease (including diabetes).<br />

Conducts Phases I – IV clinical studies. The Centre’s director,<br />

Dr. David Kendler, is Director of the Osteoporosis Program at<br />

Providence Health Care.<br />

<strong>Clinical</strong> trial research corporation specializing in support services<br />

(e.g., management, data processing <strong>and</strong> management)<br />

to biopharmaceutical companies worldwide, providing high<br />

quality information <strong>and</strong> data services through the use of<br />

electronic systems for international health research.<br />

Provides expertise in molecular medicine, biostatistics, clinical<br />

therapeutics, economics, health outcomes measurement,<br />

<strong>and</strong> economics to conduct national <strong>and</strong> international Phase<br />

I to IV clinical <strong>and</strong> pharmacovigilance studies. Extensive<br />

experience in all areas of clinical research, extending from<br />

developmental therapeutics to formal clinical trials <strong>and</strong><br />

longitudinal disease-based registry studies in a broad range<br />

of therapeutic areas from infectious diseases to complex<br />

multisystem disorders.<br />

Syreon Services Include:<br />

• Study management: Study <strong>and</strong> project management services<br />

to ensure that trials are conducted in accordance with<br />

the most stringent scientific <strong>and</strong> operational objectives. Options<br />

for Senior Tier Study Management models, customized<br />

to the requirements of each Sponsor <strong>and</strong> study, are shown in<br />

the following sections.<br />

• Site management: ClinStream technology facilitates<br />

on-line site training <strong>and</strong> certification, study education <strong>and</strong><br />

GCP training to speed IRB submission <strong>and</strong> approval, <strong>and</strong> to<br />

facilitate patient selection, enrolment <strong>and</strong> r<strong>and</strong>omization.<br />

• Monitoring Services: through a network of site monitoring<br />

Located in Vancouver.<br />

Major <strong>Clinical</strong><br />

trial management,<br />

support <strong>and</strong> operations<br />

capability<br />

based in Vancouver.<br />

Multinational CRO<br />

with divisions in<br />

Canada - Vancouver<br />

<strong>and</strong> Montreal <strong>and</strong><br />

Budapest, Hungary.<br />

Multi-centre<br />

<strong>and</strong> multinational<br />

programs<br />

integrated over<br />

1,000 academic<br />

<strong>and</strong> community<br />

sites in more than<br />

40 countries<br />

throughout the<br />

Americas, Europe,<br />

Africa, the Middle<br />

East, Australia, <strong>and</strong><br />

Asia.<br />

Syreon Committees:<br />

8 staff: 3 physicians,<br />

2 research<br />

coordinators/<br />

managers, 2 research<br />

assistants,<br />

1 admin.<br />

Types of Clients Regulatory<br />

Qualifications<br />

Large <strong>and</strong> small<br />

pharma/biotech<br />

N/A Large Pharma,<br />

SMEs Hospitals<br />

Institutions<br />

University Med<br />

schools <strong>and</strong><br />

small operations<br />

requiring<br />

CT operations<br />

services<br />

<strong>Trials</strong> comply<br />

with GCP<br />

Syreon services<br />

comply with:<br />

GCP<br />

GLP<br />

cGMP<br />

ICH


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APPENDIX 11. Independent <strong>Clinical</strong> <strong>Trials</strong> Service Companies (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

ervices.<br />

• Real-Time Data Management: Internet-based research networks<br />

enable real-time electronic data capture- recording of<br />

clinical data, with independent but simultaneous subjectbased<br />

reporting of health status <strong>and</strong> resource utilization.<br />

• ClinStream also facilitates an electronic clinical research<br />

system linking research partners in over 40 countries with<br />

speed, security <strong>and</strong> accuracy, <strong>and</strong> enables the seamless<br />

integration of clinical, laboratory, health outcomes <strong>and</strong><br />

economic data for comprehensive clinical evaluation of<br />

treatment effectiveness <strong>and</strong> value.<br />

• Pharmacovigilance: safety reports are reviewed by Medical<br />

Monitors, then processed, databased <strong>and</strong> archived by<br />

Safety Specialists, following which critical safety information<br />

is forwarded to Regulatory Authorities via CIOMS or<br />

MedWatch forms. Syreon provides 24-hour, pager-based<br />

on-call Medical monitoring services where required. Serious<br />

adverse events are assessed for expectedness, <strong>and</strong> to ensure<br />

adherence to regulatory reporting timelines.<br />

Scientific Advisory<br />

Committee providing<br />

expert advice<br />

on all relevant<br />

aspects of the<br />

program, including<br />

study protocol<br />

<strong>and</strong> analytical<br />

plan, selection<br />

of participating<br />

centres, choice <strong>and</strong><br />

use of outcome<br />

measures, review<br />

of the analysis<br />

plan, <strong>and</strong> preparation,<br />

submission<br />

<strong>and</strong> authorship of<br />

scientific communication<br />

outputs.<br />

Data or Safety<br />

Review Committee:<br />

consisting of medical<br />

<strong>and</strong> statistical<br />

experts in the<br />

relevant field<br />

Types of Clients Regulatory<br />

Qualifications


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

305<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number <strong>and</strong><br />

Type of Staffing<br />

SLC Laboratories<br />

www.slclabs.com<br />

Victoria Heart Institute<br />

Foundation<br />

www.vhif.org<br />

204 - 4475 Wayburne Drive,<br />

Burnaby, B.C. V5G 4X4<br />

Tel: 604-454-0107<br />

Fax: 604-454-0266<br />

Contact:<br />

Project Manager<br />

Arthur Yee<br />

ayee@slclabs.com<br />

#200 - 1900 Richmond Avenue,<br />

Victoria, B.C. V8R 4R2<br />

Tel: 250-595-1884<br />

Fax: 250-595-5367<br />

vhif@vhif.org<br />

Offers customized analytical <strong>and</strong> bioanalytical services to<br />

the pharmaceutical, natural health product, <strong>and</strong> functional<br />

food industries via high-throughput, automated testing of<br />

biological samples. It also provides experience in bioanalytical<br />

support for clinical studies in Japan in association with<br />

Japanese affiliate Epoch Medical International Inc.<br />

Seigiken represents method development <strong>and</strong> validation as<br />

well as sample analysis <strong>and</strong> regulatory submissions to the<br />

Pharmaceutical <strong>and</strong> Medical Safety Bureau(PMSB), Ministry<br />

of Health, Labour <strong>and</strong> Welfare of Japan.<br />

Services include:<br />

• Customized method development<br />

• Method validation for the parameters of accuracy, precision,<br />

calibration fit, recovery <strong>and</strong> stability<br />

•Instrumentation including conventional HPLC <strong>and</strong> UPLC-<br />

MS/MS<br />

• High-throughput sample analysis of biological fluids such<br />

as blood plasma for active ingredients or oxidative stress<br />

biomarkers.<br />

Oxygen Radical Absorption Capacity (ORAC) Testing:<br />

• Food or health product quality characterization<br />

• Manufacturing quality control<br />

• Marketing advantage<br />

• Active ingredient screening <strong>and</strong> discovery.<br />

Non-profit, charitable organization dedicated to conducting<br />

<strong>and</strong> supporting cardiovascular research on Vancouver Isl<strong>and</strong>.<br />

Supports a wide range of activities related to cardiovascular<br />

research, including:<br />

• Cardiovascular drug <strong>and</strong> device clinical trials,<br />

• Continuing medical education,<br />

• Training <strong>and</strong> learning opportunities for graduate trainees<br />

in cardiovascular medicine,<br />

• Publishing research results in medical journals<br />

Conducts Phases I – IV clinical trials.<br />

Analytical <strong>and</strong><br />

bioanalytical<br />

laboratory services<br />

for clinical studies<br />

Located primarily<br />

in Vancouver with<br />

Canadian <strong>and</strong> Japanese<br />

operations<br />

SLC Laboratories<br />

is operated by<br />

Seigiken Laboratories<br />

Canada Inc<br />

as a privately held<br />

Canadian corporation<br />

N/A 11 cardiologists<br />

throughout<br />

Vancouver Isl<strong>and</strong><br />

including VHIF Directors,<br />

5 clinical<br />

research nurses,<br />

1 clinical support<br />

staff, manager,<br />

accountant, 2<br />

other admin<br />

N/A Large Pharma,<br />

SMEs Hospitals<br />

Institutions<br />

University Med<br />

schools <strong>and</strong><br />

small operations<br />

requiring<br />

CT bioanalytical<br />

support<br />

Types of Clients Regulatory<br />

Qualifications<br />

Pharma, biotech,<br />

CROs, hospitals,<br />

research<br />

organizations/<br />

institutions<br />

SLC services<br />

comply with:<br />

GLP<br />

<strong>Trials</strong> comply<br />

with GCP <strong>and</strong><br />

ICH


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BRITISH COLUMBIA<br />

APPENDIX 12. PRECLINICAL STUDIES SERVICE ORGANIZATIONS<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number<br />

<strong>and</strong> Type of<br />

Staffing<br />

BCCA Investigational Drug<br />

Program (IDP)<br />

www.bccrc.ca/at/focus_investigationaldrugprogram.html<br />

B.C. Cancer Agency Research<br />

Centre<br />

675 West 10th Avenue<br />

Vancouver, B.C.<br />

V5Z 1L3<br />

Tel : 604-675-8000<br />

Head: Marcel Bally<br />

Tel :604-675-8020<br />

mbally@bccrc.ca<br />

<strong>Clinical</strong> <strong>Trials</strong> Support Services<br />

Contact: Dawn Waterhouse<br />

Tel : 604-675-8022<br />

dwater@bccrc.ca<br />

Provides facilities for the pharmaceutical formulation, manufacturing <strong>and</strong><br />

pre-clinical testing of new parenteral drugs for Phase I <strong>and</strong> II clinical trials.<br />

Complies with Good Manufacturing Practice <strong>and</strong> Good Laboratory Practice.<br />

It has a m<strong>and</strong>ate to develop promising new therapeutic agents for new<br />

anticancer agents introduction into clinical trials.<br />

IDP operates a pharmaceutical GMP clean room facility for manufacturing<br />

<strong>and</strong> packaging of parenteral drug products for Phase I <strong>and</strong> Phase II clinical<br />

trials, primarily in the cancer sector; <strong>and</strong> also non-cancer therapeutic applications.<br />

Non-<strong>Clinical</strong> Safety Studies/Toxicology<br />

Conducted by IDP through the B.C. <strong>Preclinical</strong> Research Consortium; compliant<br />

with OECD Principles of Good Laboratory Practices<br />

GMP Formulation <strong>and</strong> Manufacturing Services<br />

Services range from core batching <strong>and</strong> filling activities to comprehensive<br />

development, validation, production <strong>and</strong> documentation projects. Core<br />

services provided by Investigational Drug Program for all final drug production<br />

runs:<br />

• Process development <strong>and</strong> validation<br />

• Material control <strong>and</strong> inventory documentation<br />

•Vendor qualification<br />

• Master formula/batch record design <strong>and</strong> implementation<br />

•Batch production to 10 litres or 1500 vials/day<br />

•Facility cleaning <strong>and</strong> environmental monitoring<br />

•Sterilisation / depyrogenization of equipment <strong>and</strong> packaging materials<br />

•Basic batching processes <strong>and</strong> formulation<br />

•Product sterilization through aseptic filling of final drug product<br />

Vial sizes from 1 ml to 50 ml<br />

• Comprehensive Quality Management System<br />

• Product inspection <strong>and</strong> labeling<br />

IDP is a<br />

business<br />

unit within<br />

the BCCA,<br />

<strong>and</strong> is<br />

part of the<br />

Advanced<br />

Therapeutics<br />

Department.<br />

16 employees<br />

based in<br />

Vancouver<br />

Animal technicians:<br />

5<br />

Study Directors:<br />

2<br />

Tissue Culture<br />

Manager: 1<br />

Quality<br />

Management/<br />

Documentation:<br />

3<br />

GMP Manufacturing:<br />

2.5<br />

FTE plus 1 FTE<br />

co-op student<br />

Analytical: 2<br />

<strong>Clinical</strong> trials<br />

support: 2<br />

plus 1 co-op<br />

Types of<br />

Clients<br />

Predominantly<br />

services<br />

B.C. science<br />

community;.<br />

with some<br />

clients in<br />

Canada,<br />

North<br />

America<br />

<strong>and</strong><br />

Europe.<br />

Clients<br />

include<br />

SMEs,<br />

Hospitals,<br />

Institutions,<br />

University<br />

Med<br />

schools,<br />

<strong>and</strong> small<br />

operations<br />

requiring<br />

CT operations,<br />

manufacturing,<br />

<strong>and</strong><br />

services<br />

Regulatory<br />

Qualifications<br />

Animal<br />

facility <strong>and</strong><br />

testing areas<br />

compliant<br />

with:<br />

OECD GLP<br />

practices<br />

cGMP Clean<br />

Room Facility<br />

complies<br />

with:<br />

US FDA 21<br />

CFR Parts<br />

210 <strong>and</strong> 211<br />

Health<br />

Canada<br />

HPFBI GMP<br />

guidelines.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

307<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number<br />

<strong>and</strong> Type of<br />

Staffing<br />

<strong>Clinical</strong> <strong>Trials</strong> Support Services:<br />

• H<strong>and</strong>ling & processing of all bodily fluids<br />

• PK sample processing 24 hours/day, 7 days/week<br />

• Pharmacodynamic sample processing<br />

• Pharmacogenomic <strong>and</strong> pharmacogenetic sampling<br />

• PBMC preparation<br />

• Documentation, storage <strong>and</strong> shipment of samples<br />

• Attendance at site initiation visits<br />

• Class IIA Biosafety cabinets (certified)<br />

• Class IIB Biosafety cabinets (certified)<br />

• Restricted access laboratory<br />

Regulatory interaction/compliance <strong>and</strong> facilitation for all levels of studies<br />

Types of<br />

Clients<br />

Regulatory<br />

Qualifications


308<br />

BRITISH COLUMBIA<br />

APPENDIX 12. <strong>Preclinical</strong> Studies Service Organizations (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number<br />

<strong>and</strong> Type of<br />

Staffing<br />

Centre for Drug Research <strong>and</strong><br />

Development (CDRD)<br />

www.cdrd.ca<br />

CDRD <strong>and</strong> DDI<br />

Suite 364 2259 Lower Mall,<br />

Vancouver, B.C., V6T 1Z4<br />

Tel: 604-221-7750<br />

Fax: 604-221-7753<br />

info@cdrd.ca<br />

Director CDRD: Pieter Cullis<br />

pcullis@crdr.ca<br />

CEO: Natalie Dakers<br />

ndakers@crdr.ca<br />

Project Development: John<br />

Coleman<br />

jcoleman@cdrd.ca<br />

Tel : 604-221-7750 x 117<br />

Business Development:<br />

Kamran Alam<br />

kalam@crdr.ca<br />

Tel : 604-221-7750 x 125<br />

-<br />

Drug Development, Inc.<br />

Director Operations: Mike Parr<br />

Tel : 604-221-7750 x 176<br />

ddi@cdrd.ca<br />

CDRD provides drug development expertise <strong>and</strong> infrastructure to enable<br />

researchers throughout B.C. to develop promising drug c<strong>and</strong>idates. It has a<br />

goal to simultaneously improve efficacy, ADME, <strong>and</strong> toxicology results.<br />

The CDRD commercial arm, Drug Development Inc (DDI), licenses technologies<br />

from affiliated institutions<br />

CDRD Capabilities include:<br />

• Target Validation<br />

Genomic <strong>and</strong> proteomic techniques, including microarray analyses of gene<br />

expression, comparative proteomic analyses, <strong>and</strong> bioinformatics. This<br />

technology applies to areas as diverse as identifying novel drug targets <strong>and</strong><br />

determining side effects.<br />

• Drug Screening<br />

Drug Screening Division offers in-vitro <strong>and</strong> cell-based assays suitable for medium-<br />

to high-throughput drug screening with liquid-h<strong>and</strong>ling robots <strong>and</strong> a<br />

suite of instruments for the detection of biological or biochemical activity.<br />

• Libraries of defined pure chemicals from discovery <strong>and</strong> combinatorial<br />

chemistry, together with peptides <strong>and</strong> natural product extracts, are available<br />

for screening for potential drug activity.<br />

• Medicinal Chemistry<br />

Medicinal Chemistry Division optimizes lead compounds derived from<br />

rational design <strong>and</strong> screening processes; with modern synthetic methods<br />

<strong>and</strong> principles to design <strong>and</strong> synthesize novel compounds for biological <strong>and</strong><br />

toxicological evaluation.<br />

• Drug Delivery<br />

Drug Delivery division focuses drug formulation, both NCEs <strong>and</strong> novel macromolecular<br />

therapeutics from proteomics <strong>and</strong> genomics research.<br />

CDRD has capabilities in all types of drug formulation, <strong>and</strong> specific expertise<br />

in nano-delivery. Nano-particulate carriers can target drugs specifically to<br />

disease sites<br />

• Pharmacology <strong>and</strong> Toxicology<br />

Pharmacology <strong>and</strong> Toxicology Division provides in-vitro <strong>and</strong> in-vivo assays to<br />

determine the safety <strong>and</strong> efficacy of novel therapies. Drug-like qualities can<br />

be evaluated in vitro using a broad range of assays that measure efficacy,<br />

drug-drug interactions, cardiovascular safety, absorption, distribution,<br />

metabolism, excretion, <strong>and</strong> toxicity (ADME/Tox).<br />

CDRD is a<br />

grantfunded<br />

organisation<br />

providing<br />

for-profit<br />

services<br />

<strong>and</strong> tools<br />

used in<br />

Pharma<br />

<strong>and</strong><br />

Biomedical<br />

development.<br />

Located<br />

at UBC in<br />

Vancouver<br />

CDRD employs<br />

75 staff<br />

located in<br />

Vancouver<br />

Types of<br />

Clients<br />

CDRD<br />

provides<br />

services to<br />

predominantly<br />

287<br />

members<br />

of the B.C.<br />

science<br />

community<br />

(research<br />

institutions<br />

<strong>and</strong><br />

companies)<br />

with<br />

other<br />

clients in<br />

Canada<br />

<strong>and</strong> North<br />

America.<br />

CDRD is<br />

broadening<br />

activities<br />

beyond<br />

B.C. into<br />

other<br />

areas of<br />

Canada<br />

<strong>and</strong> North<br />

America.<br />

Regulatory<br />

Qualifications<br />

CDRD operates<br />

to:<br />

GLP


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

309<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number<br />

<strong>and</strong> Type of<br />

Staffing<br />

Product <strong>and</strong> Process Applied<br />

Research Team (PART) Technology<br />

Centre<br />

www.bcit.ca/appliedresearch/<br />

part/<br />

BCIT Technology Centre<br />

4355 Mathissi Place<br />

Burnaby B.C. V5G 4S8<br />

Tel: 604-432-8761<br />

Fax: 778-329-0314<br />

Contacts :<br />

Director of BCIT Health<br />

Technology Research Group:<br />

Nancy Paris<br />

Nancy_Paris@bcit.ca<br />

Joe Newton, Program Head<br />

joe_newton@bcit.ca<br />

PART is a specialist medical device consultancy. It provides applied research<br />

services to validate <strong>and</strong> commercialize medical, industrial <strong>and</strong> consumer<br />

products <strong>and</strong> processes, <strong>and</strong> perform contract services to research <strong>and</strong> develop<br />

proof of concept prototypes. It consists of a team of business analysts,<br />

social scientists, engineers, technologists, industrial designers, manufacturing<br />

specialists <strong>and</strong> project managers able to conduct <strong>and</strong> co-ordinate all<br />

aspects of verification <strong>and</strong> validation of a specific product’s performance.<br />

PART offers a systems based approach to strategic innovation for products<br />

<strong>and</strong> processes that exceed their expectations.<br />

Product areas include consumer <strong>and</strong> industrial electro/mechanical/textile<br />

including Medical, Safety <strong>and</strong> Assistive Devices product research & development.<br />

19 persons<br />

located in<br />

BCIT<br />

Types of<br />

Clients<br />

Applied<br />

research<br />

services<br />

provided<br />

through<br />

the BCIT<br />

(B.C.<br />

Institute of<br />

Technology)<br />

Predominantly<br />

providing<br />

development<br />

services<br />

to B.C.,<br />

including:<br />

• Starguide<br />

Technologies<br />

Inc.<br />

• UBC<br />

University<br />

Industry<br />

Liaison<br />

Office<br />

• UBC<br />

Department<br />

of<br />

Mechanical<br />

• Engineering<br />

• Hollister<br />

Incorporated<br />

• WorkSafe<br />

B.C.<br />

• B.C.<br />

Women’s<br />

<strong>and</strong><br />

Children’s<br />

Hospital<br />

Regulatory<br />

Qualifications<br />

Certified<br />

to Quality<br />

st<strong>and</strong>ards:<br />

ISO 9001 for<br />

non medical<br />

products<br />

ISO 13485<br />

for medical<br />

devices


310<br />

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APPENDIX 12. <strong>Preclinical</strong> Studies Service Organizations (cont’d)<br />

Company/ URL Contact Information Therapeutic Expertise <strong>and</strong> Types of Services Structure Number<br />

<strong>and</strong> Type of<br />

Staffing<br />

StarFish Medical<br />

www.starfishmedical.com<br />

#5-555 Ardersier Rd<br />

Victoria, B.C. V8Z 1C8<br />

Tel: 250- 388-3537<br />

Fax: 250-483-1975<br />

President: Scott Phillips<br />

sphillips@StarFishmedical.<br />

com<br />

StarFish Medical are specialists in Medical Device design, development &<br />

manufacturing.<br />

Product Development Services - StarFish Medical specializes in electro-mechanical<br />

devices, diagnostic <strong>and</strong> imaging equipment. We have expertise in<br />

a broad range of areas, including ophthalmology, h<strong>and</strong>held devices, dental<br />

equipment <strong>and</strong> radiation therapy.<br />

Comprehensive turnkey solution for developing medical device products for<br />

our clients, from concept through to manufacturing transfer<br />

Design control process to ISO 13485 certified Quality Management System.<br />

• Turnkey product development solutions<br />

• Market needs evaluation <strong>and</strong> user studies<br />

• Regulatory strategy<br />

• Quality planning<br />

• Product safety testing<br />

• Validation <strong>and</strong> clinical testing<br />

• Regulatory submissions USA, Canada, Europe<br />

• Manufacturing transfer<br />

Manufacturing Services - StarFish is registered as a manufacturer with<br />

Health Canada <strong>and</strong> the FDA, as well as CSA listed. Services include:<br />

• Product management<br />

• Manufacturing transfer<br />

• Process validation<br />

• Device master record<br />

• Change control<br />

• Device assembly<br />

• Device calibration <strong>and</strong> testing<br />

• Quality control<br />

• Bulk packaging, palleting<br />

• Finished good shipping logistics<br />

Types of<br />

Clients<br />

Employees: 35 Serves<br />

Canadian<br />

<strong>and</strong> North<br />

American<br />

companies,<br />

institutions<br />

<strong>and</strong> SMEs<br />

requiring<br />

medical<br />

devices<br />

development<br />

services<br />

Regulatory<br />

Qualifications<br />

StarFish<br />

operates<br />

under:<br />

FDA Class 2<br />

QSR / GMP<br />

ISO 13485 –<br />

1996 / CMD<br />

CAS ISO<br />

13485 –<br />

1998<br />

Medical<br />

Device Directive<br />

(MDD)<br />

93/42/EEC/<br />

Medical<br />

Devices<br />

required for<br />

CE marking.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

311<br />

APPENDIX 13. ACKNOWLEDGEMENTS<br />

This report could not have been created without the participation of the following people:<br />

Genome B.C.<br />

Gabe Kalmar, Executive Director of Operations<br />

Pierre Meulien, Chief Scientific Officer<br />

Sally Greenwood, Director, Communications<br />

Heather Harris-Harper, BCCRIN Coordinator<br />

Margaret Villacin, Administrative Assistant<br />

International BioPharma Solutions Ltd. (IBPS)<br />

Sue Kingsley, President<br />

Helen Kingsley (via IBPS)<br />

Tom Seddon (via IBPS)<br />

Heather Burt (via IBPS)<br />

Rita Jervis (via IBPS)<br />

B.C. Ministry of Small Business, Technology <strong>and</strong> Economic Development<br />

Matthew Brown, Senior Portfolio Manager, Investment Capital Branch<br />

B.C. Cancer Agency<br />

Susan O’Reilly, Vice-President, Cancer Care<br />

Delphin Racoma, Cancer Care<br />

S<strong>and</strong>ra Broughton, Regional Administrator, Centre for the Southern Interior<br />

Kim Chi, Director Medical Oncology <strong>Clinical</strong> <strong>Trials</strong> Unit, Vancouver Centre<br />

Andy Coldman, Vice President, Population Oncology<br />

Johanna den Duyf, Director, Systemic Therapy (ST) <strong>and</strong> ST <strong>Clinical</strong> <strong>Trials</strong> Unit<br />

John French, Director of <strong>Clinical</strong> Operations. Radiation Therapy Research Program, Vancouver Centre<br />

Aly Karsan, Senior Scientist, B.C. Cancer Research Centre<br />

Christopher Lee, Medical Director, Edward Miller <strong>Clinical</strong> Research Unit Fraser Valley Centre<br />

Ivo Olivotto, Head, Provincial RT Program<br />

Pauline Truong, Vancouver Isl<strong>and</strong> Centre Radiation Therapy Research Business Unit<br />

Don Wilson, Medical Director, Functional Imaging


312<br />

BRITISH COLUMBIA<br />

B.C. Centre for Disease Control<br />

Robert Brunham, Provincial Executive Director <strong>and</strong> Scientific Director<br />

Priscilla Vuong<br />

Wendy Mei, <strong>Clinical</strong> <strong>Trials</strong> Coordinator<br />

Mel Krajden, Associate Director, Laboratory Services<br />

B.C. Mental Health <strong>and</strong> Addiction Services<br />

Leslie Arnold, President<br />

Lynda Bond, Director, Research, Quality, & Performance Improvement<br />

Johann Brink, Director, <strong>Clinical</strong> Services & Scientific Director, Forensic Psychiatric Services Commission,<br />

Jana Davidson, Medical Director, Child <strong>and</strong> Adolescent Mental Health <strong>and</strong> Addiction Programs at BCCH<br />

William G. Honer, Scientific Director, B.C. Mental Health <strong>and</strong> Addictions Research Institute<br />

Child & Family Research Institute<br />

Anne Junker, Director, <strong>Clinical</strong> & Population Health Studies, Child & Family Research Institute<br />

Gordean Bjornson, Vaccine Evaluation Centre, BCCH<br />

Jennifer Claydon, Research Program Manager, BCCH<br />

Pamela Lutley, <strong>Clinical</strong> Research Coordinator, B.C. Children’s Hospital (BCCH)<br />

Vesna Popovska, Research Manager-Neurosciences Program, BCCH<br />

Terry Viczko, Research Manager, BCCH<br />

Bruce Carleton, Director, Pharmaceutical Outcomes Programme, BCCH<br />

Colin Ross, Centre for Molecular Medicine <strong>and</strong> Therapeutics<br />

Shelin Adam, Centre for Molecular Medicine <strong>and</strong> Therapeutics<br />

Fraser Health Authority<br />

Susan Chunick, Director, Department of Evaluation <strong>and</strong> Research Services<br />

Michael Wasdell, Epidemiologist, Department of Evaluation <strong>and</strong> Research Services<br />

Lynn Breakwell, SMH Cardiology <strong>Clinical</strong> <strong>Trials</strong> Inc.<br />

Steven Reynolds, Critical Care Group<br />

Ryan Tkachuk, Research Coordinator, Burnaby Hospital Regional Cancer Centre <strong>and</strong> B.C. Community<br />

Oncology Trialists<br />

Interior Health Authority<br />

Ann Ferguson, Chair, Interior Health IRB<br />

Susan Valley, Coordinator <strong>Clinical</strong> Research, Penticton Regional Hospital Research Department<br />

Paul Dagg, <strong>Clinical</strong> Director – Interior Health Tertiary Mental Health Services


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

313<br />

<strong>Life</strong> <strong>Sciences</strong> B.C.<br />

Karimah Es Sabar, Executive Director<br />

Brendan Payne, Biomedical Sector Manager<br />

Michael Smith Foundation for Health Research<br />

John Challis, President & CEO<br />

Martin Schechter<br />

Sharon Bryan<br />

Sharon Mortimer<br />

Sharlene Smith<br />

Providence Health Care Research Institute<br />

Yvonne Lefebvre, VP of Research <strong>and</strong> Academic Affairs<br />

Erin Cherban, Senior Project Manager, CIHR Canadian HIV Trial Network, <strong>and</strong> Manager, <strong>Clinical</strong> Trial<br />

Support Unit, Centre for Health Evaluation <strong>and</strong> Outcome <strong>Sciences</strong> (CHÉOS)<br />

Aslam Anis, Director, CHÉOS; National Co-Director for the CIHR Canadian HIV <strong>Trials</strong> Network<br />

Esther Wu, <strong>Clinical</strong> Research Contracts Manager<br />

William Chau, AIDS Research Program, St. Paul’s Hospital<br />

Melanie Hanson, Operations Leader, UBC James Hogg Research Centre, Providence Heart + Lung<br />

Institute, St. Paul’s Hospital<br />

Jim Pankovich, Chief Scientific Officer. CIHR Canadian HIV <strong>Trials</strong> Network, St. Paul’s Hospital<br />

Provincial Health Services Authority (PHSA)<br />

Stuart MacLeod, Vice President, Research Coordination <strong>and</strong> Academic Liaison<br />

Ellen Chesney, Chief Administrative Officer – Research<br />

Diponkar Banerjee, Executive Medical Director, PHSA Laboratory Services;<br />

Simon Fraser University<br />

Ellen Loosley, Director, Office of Research Services<br />

Mario Pinto, VP Research<br />

University of British Columbia<br />

Ariadna Fern<strong>and</strong>ez, Research Program Manager, Department of Obstetrics <strong>and</strong> Gynecology<br />

Alison Buchan, Executive Associate Dean, Research, Faculty of Medicine JP Heale, Associate Director,<br />

UBC University-Industry Liaison Office<br />

Trevor Young, Head Psychiatry Department<br />

University of Northern British Columbia<br />

Malcolm Ogborn, Associate Vice President, Research (Health)


314<br />

BRITISH COLUMBIA<br />

University of Victoria<br />

Brenda Driedger, Pre-Award Grants Officer, Office of Research Services (ORS)<br />

Dailene O’Neill, Research Programs Liaison, ORS<br />

Howard Brunt, VP Research<br />

Vancouver Coastal Health Research Institute<br />

Stephania Manusha, Regional Manager, <strong>Clinical</strong> <strong>Trials</strong> Administration,<br />

Rob McMaster, Interim Executive Director <strong>and</strong> Interim VP Research, VCH Research Institute<br />

Rebecca Fox, Manager, Cardiology Research, VGH<br />

Dawne Gillies, <strong>Clinical</strong> Research Coordinator, Vancouver Retinal Research Group, VCH<br />

Martin Gleave, Executive Director, The Vancouver Prostate Centre at Vancouver General Hospital (VGH)<br />

Maureen Palmer, The Vancouver Prostate Centre at VGH<br />

Daniel Rogers, <strong>Clinical</strong> Research Manager, VGH Nephrology Research Unit<br />

Clay Smith, Director Leukemia/ BMT Program of B.C.<br />

Harout Tossonian, Research Manager, Downtown Infectious Diseases Clinic, VCH<br />

Cindy Woo, Research Coordinator, UBC Mood Disorders Centre of Excellence<br />

Vancouver Isl<strong>and</strong> Health Authority<br />

Larry Frisch, Director of Research<br />

Women’s Health Research Institute<br />

Deborah Money, Executive Director<br />

Katherine Heath, Manager, Research Development<br />

Heather Rilkoff, Research Administrative Assistant<br />

Other<br />

Kelly Alke, Population Data B.C.<br />

Leeanna Bulinckx, President, PerCuro <strong>Clinical</strong> Research Ltd.<br />

Brent Cherban, Manager Business Development, Global Client Partners Consulting Inc.<br />

Phil Cohen, Head of the Division of Nuclear Medicine, Pacific Nuclear Medicine Inc<br />

Lisa Cruz, B.C. <strong>Preclinical</strong> Research Consortium<br />

S<strong>and</strong>ra Elias, Manager Research Education, <strong>Clinical</strong> Research Professional Development Education<br />

Program<br />

Don Enns, Former President <strong>and</strong> CEO, CANTEST Ltd.<br />

Les Gee, ASKA Research<br />

Greg Gurasci, Senior Vice President, PRA International - Victoria<br />

Yi He, Canadian Western Institutional Review Board<br />

Athena Juneson, Manager Business Development, CANTEST Ltd.


CLINICAL TRIALS AND PRECLINICAL INFRASTRUCTURE ASSET MAP<br />

315<br />

Brendan Keown, Director, Business Development, Syreon Corporation<br />

David Kwok, President, BRI Biopharmaceutical Research Inc.<br />

Paul Latimer, Okanagan <strong>Clinical</strong> <strong>Trials</strong><br />

Michele Mantle, Manager Interior <strong>Clinical</strong> Research Consultants Ltd<br />

Nancy Matthias, MSFHR B.C. Nursing Research Initiative<br />

Lorna Munro, B.C. <strong>Preclinical</strong> Research Consortium<br />

Denis Protti, Professor <strong>and</strong> Graduate Advisor, Health Information Science University of Victoria<br />

Alison Rintoul, CFRI <strong>Clinical</strong> Research Professional Development<br />

Andrew Sixsmith, Dr. Tong Louie Living Laboratory<br />

Cindy Trytten, Can-Med <strong>Clinical</strong> Research Inc.<br />

Dawn Waterhouse, BCCA Investigational Drug Program<br />

Arthur Yee, Product Manager, SLC Laboratories.


316<br />

BRITISH COLUMBIA


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