Vasculitis - Langford.pdf - AInotes

More documents

Recommendations

Info

Polyarteritis Nodosa Treatment Outcome PAN - Hepatitis B Associated anti-viral therapy plays an important role immunosuppressive therapy only as necessary to control vasculitis PAN - Non-Hepatitis Associated Based on severity Prednisone + daily cyclophosphamide for life-threatening disease Prednisone alone may be considered for non-severe disease • 80% estimated 5 year survival with treatment • Relapses occur in < 10%
Daily Cyclophosphamide A life saving drug in severe systemic vasculitis – but toxic Acute toxicities Infection Cytopenias Bladder injury Long Term Toxicities Infertility Malignancies Bladder Blood (leukemia, lymphoma) Skin (basal and squamous cell) Toxicity prevention: • Take in the AM with a large amount of fluid • CBC every 1-21 2 weeks while on drug • Urinalysis with cystoscopy for non-glomerular hematuria • Urine cytology every 6 months Cancer risk and need for surveillance is life long
Page 1 and 2: Vasculitis Carol A. Langford, MD, M
Page 3 and 4: CME Disclosure Statements Carol A.
Page 5 and 6: Vasculitis = Inflammation of the Bl
Page 7 and 8: Example Clinical Consequence Vein V
Page 9 and 10: Vein Venule Capillary Arteriole Art
Page 11 and 12: Giant Cell Arteritis (Also called t
Page 13 and 14: Giant Cell Arteritis Diagnosis Sugg
Page 15 and 16: Kawasaki Disease Diagnosis Epidemio
Page 17 and 18: Kawasaki Disease Primary complicati
Page 19 and 20: Kawasaki Disease Treatment Outcome
Page 21 and 22: Polyarteritis Nodosa Often presents
Page 23: Polyarteritis Nodosa Diagnosis Arte
Page 27 and 28: Wegener’s Granulomatosis Clinical
Page 29 and 30: Wegener’s Granulomatosis Clinical
Page 31 and 32: Antineutrophil Cytoplasmic Antibodi
Page 33 and 34: Methods of ANCA Testing Indirect Im
Page 35 and 36: Key Issues Regarding ANCA Clinical
Page 37 and 38: Wegener’s Granulomatosis Treatmen
Page 39 and 40: Microscopic Polyangiitis Clinical M
Page 41 and 42: Microscopic Polyangiitis Treatment
Page 43 and 44: Churg-Strauss Syndrome Clinical Man
Page 45 and 46: Churg-Strauss Syndrome Treatment Ou
Page 47 and 48: Henoch-Sch Schönlein Purpura 4 car
Page 49 and 50: Henoch-Sch Schönlein Purpura Treat
Page 51 and 52: Cryoglobulinemic Vasculitis Clinica
Page 53 and 54: Cryoglobulinemic Vasculitis Diagnos
Page 55 and 56: Cutaneous Leukocytoclastic Vasculit
Page 57 and 58: Urticarial Vasculitis Consists of t
Page 59 and 60: Urticarial Vasculitis Normocompleme
Page 61 and 62: Urticarial Vasculitis Hypocomplemen
Page 63 and 64: Urticarial Vasculitis Treatment Tre

Vasculitis - Langford.pdf - AInotes

Create successful ePaper yourself

Delete template?

Save as template?