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Vasculitis - Langford.pdf - AInotes

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Wegener’s Granulomatosis<br />

Treatment<br />

Outcome<br />

Prednisone + daily cyclophosphamide<br />

Prednisone + methotrexate (for mild disease)<br />

• Untreated disease – median survival time 5 months<br />

Mortality from pulmonary or renal failure<br />

• 80% survival with treatment<br />

• Relapse occurs in 50%

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