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Vasculitis - Langford.pdf - AInotes

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Antineutrophil Cytoplasmic Antibodies<br />

(ANCA)<br />

• 1982 Davies et al.<br />

Detected serum IgG antibodies that stained<br />

neutrophil cytoplasm in 8 patients with<br />

segmental necrotizing glomerulonephritis<br />

• 1985 Van der Woude et al.<br />

Demonstrated the association between<br />

cytoplasmic staining autoantibodies<br />

and active Wegener’s granulomatosis

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