Vasculitis - Langford.pdf - AInotes

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Cutaneous Leukocytoclastic <strong>Vasculitis</strong> > 70% occur in the setting of an underlying process: medication infection malignancy connective tissue disease heralding feature of a primary systemic vasculitis When no cause found: idiopathic cutaneous vasculitis Treatment: Treat/remove underlying disease/exposure when present Idiopathic: use least toxic yet effective regimen
Urticarial <strong>Vasculitis</strong> Consists of two key elements: • Clinical manifestations of urticaria • Histology: leukocytoclastic vasculitis, , largely involving postcapillary venules Skin lesions differ from common urticaria: • Wheals may have a central dark or red appearance • Lesions last > 24 hours • Often resolve with residual hyperpigmentation • Typically painful with a burning/stinging sensation • Pruritis less common than true urticaria Can be associated with systemic features • Musculoskeletal (arthralgias( arthralgias, , arthritis) • Pulmonary (COPD) • Renal • GI
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Vasculitis Carol A. Langford, MD, M
Page 3 and 4:
CME Disclosure Statements Carol A.
Page 5 and 6: Vasculitis = Inflammation of the Bl
Page 7 and 8: Example Clinical Consequence Vein V
Page 9 and 10: Vein Venule Capillary Arteriole Art
Page 11 and 12: Giant Cell Arteritis (Also called t
Page 13 and 14: Giant Cell Arteritis Diagnosis Sugg
Page 15 and 16: Kawasaki Disease Diagnosis Epidemio
Page 17 and 18: Kawasaki Disease Primary complicati
Page 19 and 20: Kawasaki Disease Treatment Outcome
Page 21 and 22: Polyarteritis Nodosa Often presents
Page 23 and 24: Polyarteritis Nodosa Diagnosis Arte
Page 25 and 26: Daily Cyclophosphamide A life savin
Page 27 and 28: Wegener’s Granulomatosis Clinical
Page 29 and 30: Wegener’s Granulomatosis Clinical
Page 31 and 32: Antineutrophil Cytoplasmic Antibodi
Page 33 and 34: Methods of ANCA Testing Indirect Im
Page 35 and 36: Key Issues Regarding ANCA Clinical
Page 37 and 38: Wegener’s Granulomatosis Treatmen
Page 39 and 40: Microscopic Polyangiitis Clinical M
Page 41 and 42: Microscopic Polyangiitis Treatment
Page 43 and 44: Churg-Strauss Syndrome Clinical Man
Page 45 and 46: Churg-Strauss Syndrome Treatment Ou
Page 47 and 48: Henoch-Sch Schönlein Purpura 4 car
Page 49 and 50: Henoch-Sch Schönlein Purpura Treat
Page 51 and 52: Cryoglobulinemic Vasculitis Clinica
Page 53 and 54: Cryoglobulinemic Vasculitis Diagnos
Page 55: Cutaneous Leukocytoclastic Vasculit
Page 59 and 60: Urticarial Vasculitis Normocompleme
Page 61 and 62: Urticarial Vasculitis Hypocomplemen
Page 63 and 64: Urticarial Vasculitis Treatment Tre
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