The 2D-ARRAY seven29 A new way of dosimetric verification of - PTW
The 2D-ARRAY seven29 A new way of dosimetric verification of - PTW
The 2D-ARRAY seven29 A new way of dosimetric verification of - PTW
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2.2 IMRT delivery techniques<br />
Several IMRT delivery techniques can be found in publications (see, e.g., [1]). Today, most <strong>new</strong>ly<br />
installed IMRT delivery systems use modulated beams with fixed beam directions. <strong>The</strong> fluence<br />
modulations are created by the multileaf collimator (MLC), which runs in one <strong>of</strong> two special IMRTmodes:<br />
• <strong>The</strong> multi-segment method approximates the continuously modulated optimized fluence <strong>of</strong> each<br />
fixed field direction by a stepwise fluence distribution. This is done by combining a set <strong>of</strong> small<br />
homogeneous field segments <strong>of</strong> different weights, which are shaped by the MLC. This method<br />
is <strong>of</strong>ten also referred to as step-and-shoot delivery, because the radiation is only turned on<br />
when the leaves have reached their prescribed positions for each segment.<br />
• A technically more advanced method is the dynamic MLC technique (<strong>of</strong>ten also called sliding<br />
window method). Here the fluence pr<strong>of</strong>ile along the moving direction <strong>of</strong> a leaf pair is created by<br />
sweeping the leaf pair with different openings over the field while the beam is on all the time.<br />
Both methods result in similar final dose distributions, although the dynamic MLC approach can<br />
generate a better approximation <strong>of</strong> the optimized fluence and allows a faster delivery. On the other<br />
hand, the multi-segment method is easier to implement and needs a slightly lower number <strong>of</strong><br />
monitor units.<br />
In contrast to conventional homogeneous fields, the number <strong>of</strong> monitor units for both methods as<br />
given by the treatment planning system no longer has a simple relation to the delivered dose <strong>of</strong><br />
that field. <strong>The</strong>refore, many groups feel it necessary to verify each single treatment field<br />
<strong>dosimetric</strong>ally before its clinical use.<br />
2.3 IMRT and quality assurance<br />
IMRT is a very complex treatment modality. <strong>The</strong>refore, <strong>new</strong> quality assurance procedures must be<br />
implemented throughout the complete clinical process [1]. Here we will only discuss some<br />
technical aspects. Typically, the clinical implementation <strong>of</strong> IMRT passes through at least three<br />
steps:<br />
1. <strong>The</strong> installation and commissioning phase <strong>of</strong> the treatment planning and the delivery system<br />
2. <strong>The</strong> clinical starting phase, where each treatment is tested by an individual <strong>verification</strong><br />
procedure, which typically is extremely time-consuming and not very standardized<br />
3. <strong>The</strong> routine phase, where standardized QA procedures are used to guarantee safe and reliable<br />
IMRT deliveries for a large number <strong>of</strong> patients<br />
Most groups focus only on the first two phases. However, the third phase is by far the most critical<br />
one for a stable IMRT routine delivery. <strong>The</strong> routine use <strong>of</strong> IMRT for large patient numbers is only<br />
possible if standardized QA procedures have been carefully defined and easy-to-use measuring<br />
equipment together with user-friendly analysis s<strong>of</strong>tware is available.<br />
For both MLC modulation methods, the delivered doses have a complex, non-intuitive relationship<br />
to the number <strong>of</strong> monitor units. It is also impossible to predict the exact combination <strong>of</strong> field<br />
segments or the leaf motion patterns. <strong>The</strong>refore, all IMRT groups, which are using the MLC for the<br />
creation <strong>of</strong> fluence modulations, must establish a precise and reliable method for the <strong>dosimetric</strong><br />
<strong>verification</strong> <strong>of</strong> IMRT plans. Especially during the starting period, each plan must be <strong>dosimetric</strong>ally<br />
verified, but <strong>dosimetric</strong> <strong>verification</strong> is also recommended after s<strong>of</strong>tware upgrades or the expansion<br />
to <strong>new</strong> tumor entities.<br />
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