Selecting and Validating Detergents for CIP Applications- An ... - A3P

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Selecting detergents & parametersLaboratory cleaning evaluation- PACE• Coat product soil onto several coupons• Dry or bake coated coupons to simulateworst-case conditions• Clean using the selected process• Screen appropriate cleaning agents• Determine appropriate worst casecleaning parameters: concentration,temperature and time• Determine cleanliness by appropriatemethods• Study soil suspension, foaming,saturation
Scaling up parameters100Manual ScrubAutomated CIP0TmeActionConcTemp
Page 1 and 2: Selecting and Validating Detergents
Page 3 and 4: Selecting cleaning agentsIssues to
Page 5 and 6: Formulated detergentsBroad-spectrum
Page 7: Cleaning process parameters andfact
Page 11 and 12: CIP cleaningWorst-case locations in
Page 13 and 14: Rinsability of formulated detergent
Page 15 and 16: Validating detergentsAcceptance cri
Page 17 and 18: Validating detergentsSampling-Clean
Page 19 and 20: Summary• Factors to consider when

Selecting and Validating Detergents for CIP Applications- An ... - A3P

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