Ensembl Compara - CNB - Protein Design Group
Ensembl Compara - CNB - Protein Design Group
Ensembl Compara - CNB - Protein Design Group
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Jul 2007ORTHEUSan ancestral sequence inference programAddresses the inference of insertiondeletion historiesand substitution eventsStarts from a (multiple) alignment and assumes afixed treeReconstructs the ancestral sequences in the tree andrefines the input alignmentInsertion/deletion events are handled using a branchtransducer modelSubstitution are handled using TamuraNeinucleotide substitution modelAncestral sequence are inferred using weightedsequence graph
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