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Persistent Pulmonary Hypertension of the Newborn - Mattel ...

Persistent Pulmonary Hypertension of the Newborn - Mattel ...

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Beyond NOToxic MoleculeLife Threatening Effects <strong>of</strong>Discontinuing INOLack <strong>of</strong> Availability <strong>of</strong> INO &/ ECMODe-regionalized neonatal careResource poor countries↓eNOS↑ETLack <strong>of</strong> Response in 30-40%Not possible to predict responseInitial response is not a guarantee <strong>of</strong>sustained responseALTERNATIVES ???Cost <strong>of</strong> INO is Exorbitant$10,142 initial charge, $10,142/day,max $25,000 per patient

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