Persistent Pulmonary Hypertension of the Newborn - Mattel ...
Persistent Pulmonary Hypertension of the Newborn - Mattel ...
Persistent Pulmonary Hypertension of the Newborn - Mattel ...
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Challenges: RCTs in PPHN• Small number <strong>of</strong> subjects?• ↓ post-term term & late preterm births• De-regionalized NICU care• Study Design Issues:• eligibility criteria - arterial line• consent• relevant outcome measures• Timeline• IND• IRB approvals