Persistent Pulmonary Hypertension of the Newborn - Mattel ...
Persistent Pulmonary Hypertension of the Newborn - Mattel ...
Persistent Pulmonary Hypertension of the Newborn - Mattel ...
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PDE5 Inhibitor - Sildenafil• In PPHN, sildenafil may:• facilitate weaning from INO• Decreases duration <strong>of</strong> mechanical ventilation,hospital stay• Sildenafil in combination with:• INO did not result in significant ↓ in systemic BP & actuallyimproved oxygenation• Milrinone (n=10) was not associated with hypotension oro<strong>the</strong>r adverse events