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Persistent Pulmonary Hypertension of the Newborn - Mattel ...

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Studies <strong>of</strong> Inhaled Prostaglandins in <strong>Pulmonary</strong><strong>Hypertension</strong> - AnimalsAuthor, yrWelte, 1993Zobel, 1995Booke, 1996Habler, 1996Habler, 1996Walmrath, 1997Krieg, 1998Ikeda, 1999Kumar, 2010PatientDrug6 dogs IPGI , INO212 piglets IPGI , 2 i.v. PGI 2 , iNO6 ewes IPGI , INO214 Healthy lambs IPGI 215 healthy lambs IPGI 2Rabbit lungINO, IPGI , IPGE 2 1 , i.v PGI 2 , i.vPGE 124 pigs INO, IPGE , 1 INO + IPGE 1Anes<strong>the</strong>tized catsINO, IPGI , 2 INO + IPGI 2 ,IPGI L2after L-NAME,Papaverine 2 mg/kg<strong>Newborn</strong> lambsIPGI 2Inhaled MilrinoneIPGI 2 + Inhaled Milrinone

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