18 de 0ctubre de 2010 www.elsuapdetodos.com1300 C.D. Deakin et al. / <strong>Resuscitation</strong> 81 (2010) 1293–1304CardioversionIf electrical cardioversion is used to convert atrial or ventriculartachyarrhythmias, the shock must be synchronised to occurwith the R wave of the electrocardiogram rather than with the Twave: VF can be induced if a shock is delivered during the relativerefractory portion of the cardiac cycle. 183 Synchronisation can bedifficult in VT because of the wide-complex and variable <strong>for</strong>ms ofventricular arrhythmia. Inspect the synchronisation marker carefully<strong>for</strong> consistent recognition of the R wave. If needed, chooseanother lead and/or adjust the amplitude. If synchronisation fails,give unsynchronised shocks to the unstable patient in VT to avoidprolonged delay in restoring sinus rhythm. Ventricular fibrillationor pulseless VT requires unsynchronised shocks. Conscious patientsmust be anaesthetised or sedated be<strong>for</strong>e attempting synchronisedcardioversion.PacingConsider pacing in patients with symptomatic bradycardiarefractory to anti-cholinergic drugs or other second line therapy(see Section 4). 113 Immediate pacing is indicated especiallywhen the block is at or below the His-Purkinje level. If transthoracicpacing is ineffective, consider transvenous pacing. Whenevera diagnosis of asystole is made, check the ECG carefully <strong>for</strong> thepresence of P waves because this will likely respond to cardiacpacing. The use of epicardial wires to pace the myocardium followingcardiac surgery is effective and discussed elsewhere. Do notattempt pacing <strong>for</strong> asystole unless P waves are present; it does notincrease short or long-term survival in- or out-of-hospital. 193–201For haemodynamically unstable, conscious patients with bradyarrhythmias,percussion pacing as a bridge to electrical pacingmay be attempted, although its effectiveness has not been established.Atrial fibrillationOptimal electrode position has been discussed previously, butanterolateral and antero-posterior are both acceptable positions.Biphasic wave<strong>for</strong>ms are more effective than monophasic wave<strong>for</strong>ms<strong>for</strong> cardioversion of AF 135–138 ; and cause less severe skinburns. 184 When available, a biphasic defibrillator should be usedin preference to a monophasic defibrillator. Differences in biphasicwave<strong>for</strong>ms themselves have not been established.Monophasic wave<strong>for</strong>msA study of electrical cardioversion <strong>for</strong> atrial fibrillation indicatedthat 360 J monophasic damped sinusoidal (MDS) shocks were moreeffective than 100 or 200 J MDS shocks. 185 Although a first shockof 360 J reduces overall energy requirements <strong>for</strong> cardioversion, 185360 J may cause greater myocardial damage and skin burns thanoccurs with lower monophasic energy levels and this must be takeninto consideration. Commence synchronised cardioversion of atrialfibrillation using an initial energy level of 200 J, increasing in astepwise manner as necessary.Biphasic wave<strong>for</strong>msMore data are needed be<strong>for</strong>e specific recommendations canbe made <strong>for</strong> optimal biphasic energy levels. Commencing at highenergy levels has not shown to result in more successful cardioversionrates compared to lower energy levels. 135,186–191 An initialsynchronised shock of 120–150 J, escalating if necessary is a reasonablestrategy based on current data.Atrial flutter and paroxysmal supraventricular tachycardiaAtrial flutter and paroxysmal SVT generally require less energythan atrial fibrillation <strong>for</strong> cardioversion. 190 Give an initial shockof 100 J monophasic or 70–120 J biphasic. Give subsequent shocksusing stepwise increases in energy. 144Ventricular tachycardiaThe energy required <strong>for</strong> cardioversion of VT depends on themorphological characteristics and rate of the arrhythmia. 192 Ventriculartachycardia with a pulse responds well to cardioversionusing initial monophasic energies of 200 J. Use biphasic energy levelsof 120–150 J <strong>for</strong> the initial shock. Consider stepwise increases ifthe first shock fails to achieve sinus rhythm. 192Implantable cardioverter defibrillatorsImplantable cardioverter defibrillators (ICDs) are becomingincreasingly common as the devices are implanted more frequentlyas the population ages. They are implanted because a patient is consideredto be at risk from, or has had, a life-threatening shockablearrhythmia and are usually embedded under the pectoral musclebelow the left clavicle (in a similar position to pacemakers,from which they cannot be immediately distinguished). On sensinga shockable rhythm, an ICD will discharge approximately 40 Jthrough an internal pacing wire embedded in the right ventricle.On detecting VF/VT, ICD devices will discharge no more than eighttimes, but may reset if they detect a new period of VF/VT. Patientswith fractured ICD leads may suffer repeated internal defibrillationas the electrical noise is mistaken <strong>for</strong> a shockable rhythm; in thesecircumstances, the patient is likely to be conscious, with the ECGshowing a relatively normal rate. A magnet placed over the ICD willdisable the defibrillation function in these circumstances.Discharge of an ICD may cause pectoral muscle contraction inthe patient, and shocks to the rescuer have been documented. 202 Inview of the low energy levels discharged by ICDs, it is unlikely thatany harm will come to the rescuer, but the wearing of gloves andminimising contact with the patient whilst the device is dischargingis prudent. Cardioverter and pacing function should always be reevaluatedfollowing external defibrillation, both to check the deviceitself and to check pacing/defibrillation thresholds of the deviceleads.Pacemaker spikes generated by devices programmed to unipolarpacing may confuse AED software and emergency personnel,and may prevent the detection of VF. 203 The diagnostic algorithmsof modern AEDs are insensitive to such spikes.www.elsuapdetodos.comReferences1. Deakin CD, Nolan JP. <strong>European</strong> <strong>Resuscitation</strong> <strong>Council</strong> guidelines <strong>for</strong>resuscitation 2005. Section 3. Electrical therapies: automated external defibrillators,defibrillation, cardioversion and pacing. <strong>Resuscitation</strong> 2005;67(Suppl.1):S25–37.2. Proceedings of the 2005 International Consensus on Cardiopulmonary<strong>Resuscitation</strong> and Emergency Cardiovascular Care Science with Treatment Recommendations.<strong>Resuscitation</strong> 2005;67:157–341.3. Larsen MP, Eisenberg MS, Cummins RO, Hallstrom AP. Predicting survivalfrom out-of-hospital cardiac arrest: a graphic model. Ann Emerg Med1993;22:1652–8.4. Valenzuela TD, Roe DJ, Cretin S, Spaite DW, Larsen MP. Estimating effectivenessof cardiac arrest interventions: a logistic regression survival model. Circulation1997;96:3308–13.5. Waalewijn RA, de Vos R, Tijssen JG, Koster RW. Survival models <strong>for</strong> out-ofhospitalcardiopulmonary resuscitation from the perspectives of the bystander,the first responder, and the paramedic. <strong>Resuscitation</strong> 2001;51:113–22.
18 de 0ctubre de 2010 www.elsuapdetodos.comC.D. Deakin et al. / <strong>Resuscitation</strong> 81 (2010) 1293–1304 13016. Weisfeldt ML, Sitlani CM, Ornato JP, et al. Survival after application of automaticexternal defibrillators be<strong>for</strong>e arrival of the emergency medical system:evaluation in the resuscitation outcomes consortium population of 21 million.J Am Coll Cardiol 2010;55:1713–20.7. Myerburg RJ, Fenster J, Velez M, et al. Impact of community-wide policecar deployment of automated external defibrillators on survival from out-ofhospitalcardiac arrest. Circulation 2002;106:1058–64.8. Capucci A, Aschieri D, Piepoli MF, Bardy GH, Iconomu E, Arvedi M. Triplingsurvival from sudden cardiac arrest via early defibrillation without traditionaleducation in cardiopulmonary resuscitation. Circulation 2002;106:1065–70.9. van Alem AP, Vrenken RH, de Vos R, Tijssen JG, Koster RW. Use of automatedexternal defibrillator by first responders in out of hospital cardiac arrest:prospective controlled trial. BMJ 2003;327:1312.10. Valenzuela TD, Bjerke HS, Clark LL, et al. Rapid defibrillation by nontraditionalresponders: the Casino Project. Acad Emerg Med 1998;5:414–5.11. Spearpoint KG, Gruber PC, Brett SJ. Impact of the Immediate Life Support courseon the incidence and outcome of in-hospital cardiac arrest calls: an observationalstudy over 6 years. <strong>Resuscitation</strong> 2009;80:638–43.12. Waalewijn RA, Tijssen JG, Koster RW. Bystander initiated actions in outof-hospitalcardiopulmonary resuscitation: results from the Amsterdam<strong>Resuscitation</strong> Study (ARREST). <strong>Resuscitation</strong> 2001;50:273–9.13. Swor RA, Jackson RE, Cynar M, et al. Bystander <strong>CPR</strong>, ventricular fibrillation, andsurvival in witnessed, unmonitored out-of-hospital cardiac arrest. Ann EmergMed 1995;25:780–4.14. Holmberg M, Holmberg S, Herlitz J. Effect of bystander cardiopulmonary resuscitationin out-of-hospital cardiac arrest patients in Sweden. <strong>Resuscitation</strong>2000;47:59–70.15. Vaillancourt C, Verma A, Trickett J, et al. Evaluating the effectiveness ofdispatch-assisted cardiopulmonary resuscitation instructions. Acad EmergMed 2007;14:877–83.16. O’Neill JF, Deakin CD. Evaluation of telephone <strong>CPR</strong> advice <strong>for</strong> adult cardiac arrestpatients. <strong>Resuscitation</strong> 2007;74:63–7.17. Yang CW, Wang HC, Chiang WC, et al. Interactive video instruction improvesthe quality of dispatcher-assisted chest compression-only cardiopulmonaryresuscitation in simulated cardiac arrests. Crit Care Med 2009;37:490–5.18. Yang CW, Wang HC, Chiang WC, et al. Impact of adding video communicationto dispatch instructions on the quality of rescue breathing in simulated cardiacarrests—a randomized controlled study. <strong>Resuscitation</strong> 2008;78:327–32.19. Koster RW, Baubin MA, Caballero A, et al. <strong>European</strong> <strong>Resuscitation</strong> <strong>Council</strong><strong>Guidelines</strong> <strong>for</strong> <strong>Resuscitation</strong> 2010. Section 2. Adult basic life support and useof automated external defibrillators. <strong>Resuscitation</strong> 2010;81:1277–92.20. Berdowski J, Schulten RJ, Tijssen JG, van Alem AP, Koster RW. Delaying a shockafter takeover from the automated external defibrillator by paramedics is associatedwith decreased survival. <strong>Resuscitation</strong> 2010;81:287–92.21. Zafari AM, Zarter SK, Heggen V, et al. A program encouraging early defibrillationresults in improved in-hospital resuscitation efficacy. J Am Coll Cardiol2004;44:846–52.22. Destro A, Marzaloni M, Sermasi S, Rossi F. Automatic external defibrillators inthe hospital as well? <strong>Resuscitation</strong> 1996;31:39–43.23. Forcina MS, Farhat AY, O’Neil WW, Haines DE. Cardiac arrest survival afterimplementation of automated external defibrillator technology in the inhospitalsetting. Crit Care Med 2009;37:1229–36.24. Domanovits H, Meron G, Sterz F, et al. Successful automatic external defibrillatoroperation by people trained only in basic life support in a simulated cardiacarrest situation. <strong>Resuscitation</strong> 1998;39:47–50.25. Cusnir H, Tongia R, Sheka KP, et al. In hospital cardiac arrest: a role <strong>for</strong> automaticdefibrillation. <strong>Resuscitation</strong> 2004;63:183–8.26. Chan PS, Krumholz HM, Nichol G, Nallamothu BK. Delayed time to defibrillationafter in-hospital cardiac arrest. N Engl J Med 2008;358:9–17.27. Cummins RO, Eisenberg MS, Litwin PE, Graves JR, Hearne TR, Hallstrom AP.Automatic external defibrillators used by emergency medical technicians: acontrolled clinical trial. JAMA 1987;257:1605–10.28. Stults KR, Brown DD, Kerber RE. Efficacy of an automated external defibrillatorin the management of out-of-hospital cardiac arrest: validation of the diagnosticalgorithm and initial clinical experience in a rural environment. Circulation1986;73:701–9.29. Kramer-Johansen J, Edelson DP, Abella BS, Becker LB, Wik L, Steen PA. Pausesin chest compression and inappropriate shocks: a comparison of manual andsemi-automatic defibrillation attempts. <strong>Resuscitation</strong> 2007;73:212–20.30. Pytte M, Pedersen TE, Ottem J, Rokvam AS, Sunde K. Comparison of hands-offtime during <strong>CPR</strong> with manual and semi-automatic defibrillation in a manikinmodel. <strong>Resuscitation</strong> 2007;73:131–6.31. Edelson DP, Abella BS, Kramer-Johansen J, et al. Effects of compression depthand pre-shock pauses predict defibrillation failure during cardiac arrest. <strong>Resuscitation</strong>2006;71:137–45.32. Eftestol T, Sunde K, Steen PA. Effects of interrupting precordial compressionson the calculated probability of defibrillation success during out-of-hospitalcardiac arrest. Circulation 2002;105:2270–3.33. Yu T, Weil MH, Tang W, et al. Adverse outcomes of interrupted precordialcompression during automated defibrillation. Circulation 2002;106:368–72.34. Wik L, Kramer-Johansen J, Myklebust H, et al. Quality of cardiopulmonaryresuscitation during out-of-hospital cardiac arrest. JAMA 2005;293:299–304.35. Abella BS, Alvarado JP, Myklebust H, et al. Quality of cardiopulmonary resuscitationduring in-hospital cardiac arrest. JAMA 2005;293:305–10.36. Kerber RE, Becker LB, Bourland JD, et al. Automatic external defibrillators <strong>for</strong>public access defibrillation: recommendations <strong>for</strong> specifying and reportingarrhythmia analysis algorithm per<strong>for</strong>mance, incorporating new wave<strong>for</strong>ms,and enhancing safety. A statement <strong>for</strong> health professionals from the AmericanHeart Association Task Force on Automatic External Defibrillation, Subcommitteeon AED Safety and Efficacy. Circulation 1997;95:1677–82.37. Dickey W, Dalzell GW, Anderson JM, Adgey AA. The accuracy of decisionmakingof a semi-automatic defibrillator during cardiac arrest. Eur Heart J1992;13:608–15.38. Atkinson E, Mikysa B, Conway JA, et al. Specificity and sensitivity of automatedexternal defibrillator rhythm analysis in infants and children. Ann Emerg Med2003;42:185–96.39. Cecchin F, Jorgenson DB, Berul CI, et al. Is arrhythmia detection by automaticexternal defibrillator accurate <strong>for</strong> children? Sensitivity and specificity of anautomatic external defibrillator algorithm in 696 pediatric arrhythmias. Circulation2001;103:2483–8.40. van Alem AP, Sanou BT, Koster RW. Interruption of cardiopulmonary resuscitationwith the use of the automated external defibrillator in out-of-hospitalcardiac arrest. Ann Emerg Med 2003;42:449–57.41. Rea TD, Helbock M, Perry S, et al. Increasing use of cardiopulmonary resuscitationduring out-of-hospital ventricular fibrillation arrest: survival implicationsof guideline changes. Circulation 2006;114:2760–5.42. Gundersen K, Kvaloy JT, Kramer-Johansen J, Steen PA, Eftestol T. Developmentof the probability of return of spontaneous circulation in intervals withoutchest compressions during out-of-hospital cardiac arrest: an observationalstudy. BMC Med 2009;7:6.43. Lloyd MS, Heeke B, Walter PF, Langberg JJ. Hands-on defibrillation: an analysisof electrical current flow through rescuers in direct contact with patientsduring biphasic external defibrillation. Circulation 2008;117:2510–4.44. Miller PH. Potential fire hazard in defibrillation. JAMA 1972;221:192.45. Hummel III RS, Ornato JP, Weinberg SM, Clarke AM. Spark-generating propertiesof electrode gels used during defibrillation. A potential fire hazard. JAMA1988;260:3021–4.46. ECRI. Defibrillation in oxygen-enriched environments [hazard]. Health Devices1987;16:113–4.47. Lefever J, Smith A. Risk of fire when using defibrillation in an oxygen enrichedatmosphere. Med Devices Agency Safety Notices 1995;3:1–3.48. Ward ME. Risk of fires when using defibrillators in an oxygen enriched atmosphere.<strong>Resuscitation</strong> 1996;31:173.49. Theodorou AA, Gutierrez JA, Berg RA. Fire attributable to a defibrillationattempt in a neonate. Pediatrics 2003;112:677–9.50. Robertshaw H, McAnulty G. Ambient oxygen concentrations during simulatedcardiopulmonary resuscitation. Anaesthesia 1998;53:634–7.51. Cantello E, Davy TE, Koenig KL. The question of removing a ventilation bagbe<strong>for</strong>e defibrillation. J Accid Emerg Med 1998;15:286.52. Deakin CD, Paul V, Fall E, Petley GW, Thompson F. Ambient oxygen concentrationsresulting from use of the Lund University Cardiopulmonary Assist System(LUCAS) device during simulated cardiopulmonary resuscitation. <strong>Resuscitation</strong>2007;74:303–9.53. Kerber RE, Kouba C, Martins J, et al. Advance prediction of transthoracicimpedance in human defibrillation and cardioversion: importance ofimpedance in determining the success of low-energy shocks. Circulation1984;70:303–8.54. Kerber RE, Grayzel J, Hoyt R, Marcus M, Kennedy J. Transthoracic resistance inhuman defibrillation. Influence of body weight, chest size, serial shocks, paddlesize and paddle contact pressure. Circulation 1981;63:676–82.55. Sado DM, Deakin CD, Petley GW, Clewlow F. Comparison of the effects ofremoval of chest hair with not doing so be<strong>for</strong>e external defibrillation ontransthoracic impedance. Am J Cardiol 2004;93:98–100.56. Walsh SJ, McCarty D, McClelland AJ, et al. Impedance compensated biphasicwave<strong>for</strong>ms <strong>for</strong> transthoracic cardioversion of atrial fibrillation: a multi-centrecomparison of antero-apical and antero-posterior pad positions. Eur Heart J2005;26:1298–302.57. Deakin CD, Sado DM, Petley GW, Clewlow F. Differential contribution of skinimpedance and thoracic volume to transthoracic impedance during externaldefibrillation. <strong>Resuscitation</strong> 2004;60:171–4.58. Deakin C, Sado D, Petley G, Clewlow F. Determining the optimal paddle <strong>for</strong>ce<strong>for</strong> external defibrillation. Am J Cardiol 2002;90:812–3.59. Manegold JC, Israel CW, Ehrlich JR, et al. External cardioversion of atrial fibrillationin patients with implanted pacemaker or cardioverter-defibrillatorsystems: a randomized comparison of monophasic and biphasic shock energyapplication. Eur Heart J 2007;28:1731–8.60. Alferness CA. Pacemaker damage due to external countershock in patientswith implanted cardiac pacemakers. Pacing Clin Electrophysiol 1982;5:457–8.61. Panacek EA, Munger MA, Ruther<strong>for</strong>d WF, Gardner SF. Report of nitropatchexplosions complicating defibrillation. Am J Emerg Med 1992;10:128–9.62. Wrenn K. The hazards of defibrillation through nitroglycerin patches. AnnEmerg Med 1990;19:1327–8.63. Pagan-Carlo LA, Spencer KT, Robertson CE, Dengler A, Birkett C, KerberRE. Transthoracic defibrillation: importance of avoiding electrode placementdirectly on the female breast. J Am Coll Cardiol 1996;27:449–52.64. Deakin CD, Sado DM, Petley GW, Clewlow F. Is the orientation of the apicaldefibrillation paddle of importance during manual external defibrillation?<strong>Resuscitation</strong> 2003;56:15–8.65. Kirchhof P, Eckardt L, Loh P, et al. Anterior-posterior versus anterior-lateralelectrode positions <strong>for</strong> external cardioversion of atrial fibrillation: a randomisedtrial. Lancet 2002;360:1275–9.www.elsuapdetodos.com