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Guidelines on the Prevention and Control of Tuberculosis in Ireland

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<str<strong>on</strong>g>Guidel<strong>in</strong>es</str<strong>on</strong>g> <strong>on</strong> <strong>the</strong> Preventi<strong>on</strong> <strong>and</strong> C<strong>on</strong>trol <strong>of</strong> <strong>Tuberculosis</strong> <strong>in</strong> Irel<strong>and</strong> 2009HSE/HPSCable to overcome <strong>the</strong> bacteria. The bacteria become <strong>in</strong>active but <strong>the</strong>y rema<strong>in</strong> dormant <strong>in</strong> <strong>the</strong> body <strong>and</strong> canbecome active later. This is called latent TB <strong>in</strong>fecti<strong>on</strong> (LTBI).People with LTBI:• Have no symptoms• D<strong>on</strong>’t feel sick• Can’t spread TB to o<strong>the</strong>rs• Usually have a positive sk<strong>in</strong> test reacti<strong>on</strong>• Can develop TB disease later <strong>in</strong> life.Most people who have LTBI never develop active TB disease. In <strong>the</strong>se people, <strong>the</strong> TB bacteria rema<strong>in</strong><strong>in</strong>active for a lifetime without caus<strong>in</strong>g disease. But <strong>in</strong> o<strong>the</strong>r people, who have weak immune systems, <strong>the</strong>bacteria can become active <strong>and</strong> cause TB disease.The difference between latent TB <strong>in</strong>fecti<strong>on</strong> <strong>and</strong> active TB diseaseA pers<strong>on</strong> with Latent TB Infecti<strong>on</strong>• Has no symptoms• Does not feel sick• Usually has a positive sk<strong>in</strong> test orblood test• Has a normal chest X-ray <strong>and</strong>sputum testA pers<strong>on</strong> with Active TB Disease• Has symptoms which may <strong>in</strong>clude:A bad cough which lasts three weeks or l<strong>on</strong>gerPa<strong>in</strong> <strong>in</strong> <strong>the</strong> chestCough<strong>in</strong>g up sputum (phlegm) or bloodWeakness or fatigueWeight lossNo appetiteChillsFeverNight sweats• May spread TB to o<strong>the</strong>rs• Usually has a positive sk<strong>in</strong> test or positive blood test• May have an abnormal chest X-ray or positive sputumsmearor cultureHow is TB diagnosed?There are a number <strong>of</strong> tests that can be d<strong>on</strong>e to check for TB:• A sk<strong>in</strong> test• A chest X-ray• A test <strong>of</strong> <strong>the</strong> sputum (phlegm)• A blood or ur<strong>in</strong>e test.How is TB treated?Yes, today TB is potentially completely curable, if <strong>the</strong> resp<strong>on</strong>sible organism is fully sensitive to <strong>the</strong>antibiotics be<strong>in</strong>g used <strong>and</strong> <strong>the</strong> patient takes his or her medicati<strong>on</strong> as prescribed.TB is treated with tablets which must be taken for at least six m<strong>on</strong>ths. Without treatment, many peopleused to die from TB. It is essential to take <strong>the</strong> treatment regularly <strong>and</strong> to complete <strong>the</strong> course asprescribed.The most comm<strong>on</strong> medic<strong>in</strong>es used to treat TB are: is<strong>on</strong>iazid, rifampic<strong>in</strong>, ethambutol <strong>and</strong> pyraz<strong>in</strong>amide. Avitam<strong>in</strong> B6 tablet called pyridox<strong>in</strong>e is also prescribed to help prevent some <strong>of</strong> <strong>the</strong> side effects that may becaused by is<strong>on</strong>iazid. Your doctor will decide which TB drugs are best for you.-164-

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