Relevance of Sperm DNA Fragmentation - eshre

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The potential detrimental effect of density gradient centrifugationon sperm DNA integritiy is related to initial semen quality (Zini)Sperms of infertile patients are more susceptible to externalSperms of infertile patients are more susceptible to externalinfluences
Page 1 and 2: Relevance of Sperm DNAFragmentation
Page 3: 1. Sperm DNA peculiarityDuring sper
Page 6 and 7: In mature sperm the DNA is• 85% p
Page 8: 2. Etiology of DNA Damagethe etiolo
Page 11 and 12: ROS• Small levels are essential f
Page 13 and 14: 3. DNA Fragmentation TestsDFI: DNA
Page 15 and 16: TUNEL assayLabels single and double
Page 17 and 18: SCD or Halo TestThe SCD is based on
Page 20 and 21: 4. Influence of lab procedures
Page 25 and 26: Sperm processing and DFI• DFI Lev
Page 27 and 28: Ebner et al, 2010
Page 29 and 30: 39 patientswith male subfertility(5
Page 31 and 32: • Motility seems to be the utmost
Page 33 and 34: Correlation of sperm parametersand
Page 35 and 36: DFI and IUI• withaDFI< 27% the ch
Page 37 and 38: Ahi Achievement of pregnancy:- 84%
Page 39: Retrospective study on 282 patients
Page 44: DFI and pregnancy loss
Page 47 and 48: Let´s not forget the oocyte
Page 49 and 50: Conclusions I• Infertile men have
Page 51: ThomasMeManuelaRenateThank you for
Page 54: Is sperm dna damage associated with

Relevance of Sperm DNA Fragmentation - eshre

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