Relevance of Sperm DNA Fragmentation - eshre
Relevance of Sperm DNA Fragmentation - eshre
Relevance of Sperm DNA Fragmentation - eshre
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In mature sperm the <strong>DNA</strong> is• 85% protamine bound• 15 % remains histone boundprotamine deficiency: more susceptible for ROSInfertile men have a higher histone:protamine ratio than fertile men(Oliva 2006, Zhang 2006)5-10% <strong>of</strong> infertile men have a complete protamine deficiency