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Relevance of Sperm DNA Fragmentation - eshre

Relevance of Sperm DNA Fragmentation - eshre

Relevance of Sperm DNA Fragmentation - eshre

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protamines• Are proteins with a high content <strong>of</strong> positively chargedamino acids (48% arginine)• Form a highly condensed complex with the sperm <strong>DNA</strong>(<strong>DNA</strong> has a strong negative charge)• Incorporate cysteins• Cysteins allow the formation <strong>of</strong> disulphide bondsbetween the protamines• Therefore strongly stabilize the nucleoprotaminecomplex

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