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Oral presentationZEARALENONE INDUCES HEPATOCYTES DAMAGE IN WISTARRATS AFTER ORAL APPLICATIONBabić Mirsad 1 , Radović S 1 , Dorić M 1 , Selak I 1 , Tomić I 1 , Ožegović L 21Institute of pathology Medical Faculty of Sarajevo2Academy of Sciences and Arts of Bosnia andHerzegovinaE-mail: mirsadbabic@yahoo.comObjective: Mycotoxin zearalenone is a product of fungiFusarium species which has activity similar to estrogen.Aim was to investigate toxic effects of mycotoxin zearalenoneon hepatocytes of experimental Wistar rats followingoral application.Material and methods: We used 42 experimental Wistarrats and orally applied mycotoxin dissolved in oilin different concentrations, 0,5 mg , 2 mg and 4 mg perkilogram of body weight, in the three time periods -10, 20 and 30 days. The liver tissue fixed in bufferedformaldehyde. Paraffin slices, 4 microns thicknesswere stained with histochemical and immunochemicalmethods.Results: Examination proved focal necrosis with depletionof PAS positive material in hepatocytes cytoplasmat all groups which received different doses. The mostexpressive focal necrosis was in group who receiveddoses of 0,5 mg ( p=0,005).Conclusion: In rats liver zearalenone caused focalnecrosis of hepatocytes. The experiment didn’t provesigns non-parenchymatous liver damage at mycotoxinactivity in the three different doses and periods.Key words: zearalenone, hepatocytes, focal necrosis,Wistar rats.10
Oral presentationEVALUATION OF ANTHROPOMETRIC INDICESIN DIABETIC PATIENTSNermina Babic 1 , Zelija Velija-Asimi 2 , Jasminko Huskic 1 , Amela Dizdarevic-Bostandzic 2 , Alma Mujanovic-Narancic 2 , Emina Nakas-Icindic1Institute of Physiology and Biochemistry,Medical Faculty, University of Sarajevo, Sarajevo,Bosnia and Herzegovina2Clinics for Endocrinology, Diabetes Mellitus andMetabolic Diseases, University Clinical Center ofSarajevo, Sarajevo, Bosnia and HerzegovinaE-mail: nerminab@yahoo.comIntroduction: Abdominal obesity is a significant riskfactor for cardiovascular diseases. The aim: To researcha relationship between an abdominal adiposity, assessedby various anthropometric indices (body massindex (BMI), waist circumference (WC), waist-to-hipratio (WHR), waist-to-height ratio (W/HtR)), withpulse pressure (PP) in diabetic patients.Methods: The study included 30 patients with diabetesmellitus Type 1 (DM1), 30 patients with diabetes mellitusType 2 (DM2) and 30 healthy subjects. Anthropometricmeasurements were made for all subjects,including body height, weight, waist and hip circumference.All subjects were measured blood pressure.Results: All examined anthropometric indices and PPwere statistically significantly higher in patients withDM2, compared with other groups (p
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Page 6 and 7: Editor-in-ChiefBakir MehićExecute
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Page 12 and 13: Oral presentationCOMPARATIVE ANTROP
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Page 16 and 17: Oral presentationTREATMENT OF CONGE
Page 18 and 19: Oral presentationHALLUX VALGUS DEFO
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Page 24 and 25: Oral presentationHepatic steatosis
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Poster presentationINCIDENCE, POSIT
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Poster presentationTHE ACCUMULATION
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