2005 Edition Report on Drug Administration Procedure & Practices ...

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Appendix 6HA Guideline on Safe Management ofPotassium Chloride IV SolutionsUpdated in Apr 08
HA Guideline on Safe Management of Potassium Chloride IV SolutionsSubject Officers:Prepared By:Approved By:Chief Manager (Q&RM)Chief PharmacistFirst Issue Date: Dec 1998Reviewed Date: May 2007Effective Date: 1 July 2007File No:HAHO Medication Safety CommitteeCentral Committee on Quality and Risk ManagementDrug Utilisation Review CommitteeMSC/0011. BackgroundIntravenous potassium chloride is indicated in the treatment of potassium deficiency stateswhen oral replacement is clinically inappropriate. Concentrated potassium chloride (14.9%)IV solution has potential risks to cause serious harm to patients, and can be fatal if giveninappropriately. This guideline is the revised version of the previous “Handling and StorageGuidelines of Potassium Chloride Injection” issued in 1998 which has been included in theDrug Administration Procedures & Practices in Public Hospitals <strong>2005</strong> edition. It aims tointroduce procedures for the safety controls of potassium chloride IV solutions, to limit andensure safe use of concentrated potassium chloride in clinical areas.2. SupplyA. Concentrated potassium chloride injection (MUST BE DILUTED before use)• Potassium chloride 14.9% (20mmol) in 10ml ampouleB. Pre-mixed Concentrated potassium chloride minibags (For use only with a calibratedinfusion device) for exceptional circumstances e.g. acute correctionIn 100ml preparations• Potassium chloride 10mmol (10mEq) in 100ml water for injection (New)• Potassium chloride 20mmol (20mEq) in 100ml water for injection (New)C. Pre-mixed potassium chloride solutions (Ready to Use)- should be used whenever possibleIn 500ml preparations• Potassium chloride 10mmol in 500ml D5 (5% Dextrose)• Potassium chloride 10mmol in 500ml NS (0.9% Sodium Chloride)• Potassium chloride 10mmol in 500ml ½:½ (0.45% Sodium Chloride:2.5% Dextrose)• Potassium chloride 20mmol in 500ml D5 (5% Dextrose)• Potassium chloride 20mmol in 500ml NS (0.9% Sodium Chloride)• Potassium chloride 20mmol in 500ml ½:½ (0.45% Sodium Chloride:2.5% Dextrose)In 1L preparation• Potassium chloride 20mmol in 1L NS (0.9% Sodium Chloride)Page 1/3
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ForewordMedication safety and provi
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Chapter 6 summarizes the specific r
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Chapter 6Conclusions and Recommenda
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CHAPTER ONETHE WORKING GROUPMEMBERS
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CHAPTER TWOTHE PROGRESS REPORT2.1 P
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CHAPTER THREEAREAS FOR IMPROVEMENT
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Existing In-patient Drug Administra
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Page 20 and 21: Existing In-patient Drug Administra
Page 22 and 23: CHAPTER FOURRECOMMENDED PRACTICES A
Page 24 and 25: Drug Name4.11 There should be a hos
Page 26 and 27: Electronic prescribing (Medication
Page 28 and 29: 4.46 When the use of CM is permitte
Page 30 and 31: cytotoxic and central intravenous a
Page 32 and 33: 4.72 Special precautions should be
Page 34 and 35: 4.84 To prevent mixing up medicatio
Page 36 and 37: The Principle of Three checks and F
Page 38 and 39: 4.111 Three-way (red and blue) and
Page 40 and 41: or their discharge or death, should
Page 42 and 43: operational requirement but also it
Page 44 and 45: Quality Complaints on Pharmaceutica
Page 46 and 47: LEVELSHAHOCE / DTOOLS & MECHANISMDU
Page 48 and 49: Medication Incident Report<
Page 50 and 51: Continuing Education6.18 In order t
Page 52 and 53: APPENDICESAppendix 1Appendix 2Appen
Page 54 and 55: Hospital Authority Hospital No. : I
Page 56 and 57: Sensitivity:Prescription/ routewith
Page 58 and 59: Appendix 3aLists of HA-wide Approve
Page 60 and 61: DRUGTeniposideABBREVIATIONVM-26Thia
Page 62 and 63: Appendix 3b“Do Not Use Abbreviati
Page 64 and 65: Appendix 4Schedule for the Administ
Page 66 and 67: Appendix 5Mechanism for the Managem
Page 68 and 69: 4. As with all medications, there s
Page 72 and 73: 2.1 Concentrated potassium chloride
Page 74 and 75: Appendix 7Supply of Antidotes and D
Page 76 and 77: 複本 Antidotes and emeg drug lis
Page 78 and 79: Appendix 8Guidelines for Supply of
Page 80 and 81: substitution with other drugs in ac
Page 82 and 83: Appendix 9Samples of the Line Label
Page 84 and 85: Appendix 10Guidelines on the use of
Page 86 and 87: Appendix 11Guidelines on Patient Se
Page 88 and 89: Operational Guidelines7. The operat
Page 90 and 91: COC(N) Paper 12/2004Approved by COC
Page 92 and 93: 7.4 Evaluation Record and report th
Page 94 and 95: DISPOSAL OF HOSPITAL PHARMACEUTICAL
Page 96 and 97: Appendix 14Guidelines on the Handli
Page 98 and 99: Appendix 15Medication Incident <str
Page 100 and 101: Hospital Authority Medication Incid
Page 102 and 103: QUALITY ASSURANCE IN DRUG THERAPYHO
Page 104 and 105: Fig. 1: ADR voluntary reporting sys
Page 106 and 107: PROCEUDRE FOR QUALITY COMPLAINTSONP
Page 108: Part II Procurement Section, CPO1.
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