P/ACE MDQThe P/ACE MDQ is an advanced CE system designed, in terms of flexibility and capacity, to meet the different requirements of research,methods development and quality control laboratories. Each configuration is available with a series of options to customize to meet end-userrequirements.All P/ACE MDQ configurations combine hardware, software and chemistry with worldwide technical support. A choice of interchangeable<strong>detectors</strong> meets the needs of a wide range of applications. The software automates all operations, from direct instrument control to data acquisition,analysis and reporting. At the heart of the MDQ is the system’s flexibility in programming and capacity. In methods development, samples can beautomatically run against an array of up to 36 different pairs of buffers, while in quality control the buffer array can be switched for buffer capacity(large volume reservoir) enabling routine analysis of up to 96 samples. The P/ACE MDQ works with a range of sample vessels accommodating96-well plates or a 48-position tray that holds 2 mL vials, 0.5 mL tubes and PCR* reaction vials. The system’s built in software features assistin meeting GLP and CGMP compliance requirements. P/ACE MDQ is specially designed to meet industry’s demands for ruggedness and safety.<strong>Beckman</strong> <strong>Coulter</strong> validates system performance upon installation and provides a comprehensive compliance protocol.* PCR is covered by U.S. patents owned by Hoffmann-La Roche Inc.P/ACE MDQ Methods Development SystemPART NUMBERPART NUMBER149817 North America International 285400A CE-based analytical system configured optimally for the methodsdevelopment process, where a focus is placed on spectral analysis and theautomation of separation strategies. The system includes a P/ACE MDQconfigured with both a photo diode array and selectable-wavelength UV/Vis(200, 214, 254 and 280 nm filters included) detector, UV source optics,temperature-controlled sample storage module and 32 Karat Softwareconfigured on an IBM personal computer. Installation Qualification,Operation Qualification 1 (OQ1) and documentation to aid in softwarevalidation is also included.Starter chemistries: P/ACE MDQ Methods Development Kit, AmineCapillary Validation Pack and the Neutral Capillary Validation Pack.P/ACE MDQ Chiral SystemPART NUMBERPART NUMBER149833 North America International 285402A CE-based analytical system configured optimally for developing methodsfor the separation of enantiomers. The system includes a P/ACE MDQconfigured with a photo diode array detector, UV source optics, ambientsample storage module and 32 Karat software configured on an IBMpersonal computer. Installation Qualification, Operation Qualification 1(OQ1) and documentation to aid in software validation is also included.Starter chemistries: The Highly Sulfated Cyclodextrins chiral methodsdevelopment pack (strategy # 1), Neutral CD Chiral Methods DevelopmentKit (strategy #2), and Chiral Methods Development Guide.P/ACE MDQ Quality Control SystemPART NUMBERPART NUMBER149815 North America International 285401<strong>Beckman</strong> <strong>Coulter</strong>ContentsA CE-based analytical system configured optimally for the qualityassurance laboratory. With a focus on repetitive robust analyses, thesystem includes a P/ACE MDQ configured with a filter-based selectablewavelengthUV/Vis (200, 214, 254 and 280 nm included) detector,UV source optics, ambient sample storage module, and 32 Karat Softwareconfigured on an IBM personal computer. Installation Qualification,Operation Qualification 1 (OQ1), and documentation to aid in softwarevalidation are also included.Index6
P/ACE MDQP/ACE MDQ-LCQ CE-MS/MS SystemsPART NUMBERPART NUMBER149016These systems feature single-point control of both the ThermoFinniganLCQ and the <strong>Beckman</strong> <strong>Coulter</strong> P/ACE MDQ using the Xcalibur workstation. The P/ACE MDQ is configured with diode array detection,sample tray temperature control, and capillary temperature controlextended to an electrospray interface. The unique system interfaceemploys a liquid sheath make-up flow to sweep the analytes off thecapillary and into the mass spectrometer. The LCQ utilizes ion traptechnology to resolve the molecular ions and is capable of MS/MS—allowing these ions to be isolated and further fragmented to gainstructural information and higher confidence confirmation. Thesesystems have been optimized for capillary lengths and instrumentlevels—and configured for the following three applications (pleasecontact your local <strong>Beckman</strong> <strong>Coulter</strong> representative for a quotation onthe following systems):1) CE-MS/MS Protein Characterization System2) CE-MS/MS Pharmaceutical Analysis System3) CE-MS/MS Research SystemP/ACE MDQ Glycoprotein SystemPART NUMBERPART NUMBER149893 North America International 149872CE-based system for the separation and characterization of proteinsand associated carbohydrates. The system is ideal for peptide mapping,separation of proteins by molecular weight, accurate isoelectric point(pI) determination, oligosaccharide profiling and monosaccharideanalysis. System includes a P/ACE MDQ configured with a selectablewavelength UV/Vis (200, 214, 254 and 280 nm included) detector,UV source optics, laser-induced fluorescence detector, 488 nm argonion laser module, a temperature-controlled sample storage module,and 32 Karat Software configured on an IBM personal computer.Installation Qualification, Operation Qualification 1 (OQ1) anddocumentation to aid in software validation is also included.Starter chemistries: eCAP Carbohydrate Labeling and Analysis Kit,eCAP SDS 14-200 Kit, MDQ Methods Development kit, LIF and UVdetector test mix, and Glycoprotein Methods Development Guide.<strong>Beckman</strong> <strong>Coulter</strong>ContentsIndex7