p/ace™ mdq detectors - Beckman Coulter

P/ACE MDQ AND CEQ SYSTEMSP/ACE MDQ DNA SystemPART NUMBERPART NUMBER149892 North America International 149874A CE-based system for the analysis of nucleic acids. The system providesclear advantages over traditional electrophoresis for DNA quantitation(viral load, gene expression), mutation analysis, and size polymorphismsanalysis (VNTR, STR, microsatellites, RFLP, RAPD). System includesa P/ACE MDQ configured with a laser-induced fluorescence detector,488 nm argon ion laser module, an ambient sample storage module, and32 Karat Software configured on an IBM personal computer. InstallationQualification, Operation Qualification 1 (OQ1) and documentation to aidin software validation is also included.Starter chemistries: eCAP dsDNA 1000 kit, eCAP dsDNA 20,000 kit,EnhanCE DNA intercalator, LIF detector test mix, and Nucleic AcidsMethods Development Guide.CEQ 2000XL DNA ANALYSIS S Y STEMThe CEQ 2000XL DNA Analysis System is a fully automated, high-throughput sequencing and fragment analysis system. Capillaryelectrophoresis technology and laser-induced fluorescence detection have been combined to provide a very easy to use microplatebasedsystem. The CEQ is designed to handle all aspects of the DNA analysis process from sample denaturation through automaticbase or allele calling, with no user intervention, following an easy ten minute setup.KEY FEATURES OF THE CEQ 2000XL• Linear Polyacrylamide Gel matrix inside a coated capillary array provides the best read length/cycle time and the highest accuracyof any CE-based sequencer.• Eight capillary array to eliminate plate cleaning, gel casting, and tedious DNA sample loading.• 96-well microplate format.• Automated: loading of separation gel, sample denaturation, and sample loading.• Automatically switches between sequencing applications and fragment analysis on the same plate.For Sequencing:• Longer reads and faster cycle times (>700 bases in less than 100 minutes at better than 98% accuracy).• Short reads and faster cycle times (>500 bases in less than 45 minutes at better than 98% accuracy).• Dideoxy-terminator cycle sequencing kits with four “WellRED” fluorescence dyes (one-tube chemistry).• Raw data and analyzed data available in most popular formats.• Confidence values and call scores provided with each base determined.For Fragment Analysis:• Automated allele determination.• Precisely sized microsatellite amplification products to a S.D. of ≤0.27 bases.PART NUMBER285501 WorldwideThe CEQ 2000XL DNA analysis system is a fully automated, highperformancesequencing and fragment analysis system, employing aneight-capillary array to increase sample throughput, and specializedlaser-induced fluorescence detection optics with WellRED dyes(infrared emission) for unsurpassed performance in dideoxy terminatorcycle sequencing. Sample introduction is done directly from a 96-wellmicroplate, compatible with most forms of sample prep automation.The CEQ 2000XL handles all aspects of the DNA analysis process,from sample denaturation through automatic base or allele calling withno user intervention. This system includes the CEQ 2000XL instrument,software for both sequencing and fragment analysis, an IBMworkstation, installation and basic training.Beckman CoulterContentsIndex9