12.07.2015 Views

Bartonella quintana

Bartonella quintana

Bartonella quintana

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The best treatment for bacillary angiomatosis iserythromycin. The recommended treatment is as follows:• Erythromycin : 500 mg qid orally, for 3 monthes.Doxycycline is photosensitive and can be responsible burnafter exposition to the sun. Gentamicin is nephrotoxic, i.e.toxic for the kidneys and ototoxic, i.e. toxic for the audition.Erythromycin can be responsible for digestive disorders andmore rarely for allergic manifestations and medicamentoushepatitis.References1. Foucault C, Raoult D, Brouqui P. Randomized open trial ofgentamicin and doxycycline for eradication of <strong>Bartonella</strong><strong>quintana</strong> from blood in patients with chronic bacteremia.Antimicrob Agents Chemother 2003; 47:2204-7.2. Rolain JM, Brouqui P, Koehler JE, Maguina C, Dolan MJ,Raoult D. Recommendations for treatment of humaninfections caused by <strong>Bartonella</strong> species. Antimicrob AgentsChemother 2004; 48:1921-33.3. Raoult D, Fournier PE, Vandenesch F, et al. Outcome andtreatment of <strong>Bartonella</strong> endocarditis. Arch Intern Med 2003;163:226-30.Tableau 1. Therapeutic recommendations for the treatmentof B. <strong>quintana</strong> infectionsDisease Adults Children ReferenceTrench fever and Doxycycline 200 mg/d for 4Chronic weeks and Gentamicin 3 unknown 1 et 2bacteremias mg/kg/d for 2 weeksErythromycin 2A n g i o m a t o s e Erythromycine 2 g/d for 3g / d f o r 3bacillaire monthsmonths3Erythromycin 2Erythromycin 2 g/d for 4Hepatic peliosis g / d f o r 4monthsmonths3

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