The best treatment for bacillary angiomatosis iserythromycin. The recommended treatment is as follows:• Erythromycin : 500 mg qid orally, for 3 monthes.Doxycycline is photosensitive and can be responsible burnafter exposition to the sun. Gentamicin is nephrotoxic, i.e.toxic for the kidneys and ototoxic, i.e. toxic for the audition.Erythromycin can be responsible for digestive disorders andmore rarely for allergic manifestations and medicamentoushepatitis.References1. Foucault C, Raoult D, Brouqui P. Randomized open trial ofgentamicin and doxycycline for eradication of <strong>Bartonella</strong><strong>quintana</strong> from blood in patients with chronic bacteremia.Antimicrob Agents Chemother 2003; 47:2204-7.2. Rolain JM, Brouqui P, Koehler JE, Maguina C, Dolan MJ,Raoult D. Recommendations for treatment of humaninfections caused by <strong>Bartonella</strong> species. Antimicrob AgentsChemother 2004; 48:1921-33.3. Raoult D, Fournier PE, Vandenesch F, et al. Outcome andtreatment of <strong>Bartonella</strong> endocarditis. Arch Intern Med 2003;163:226-30.Tableau 1. Therapeutic recommendations for the treatmentof B. <strong>quintana</strong> infectionsDisease Adults Children ReferenceTrench fever and Doxycycline 200 mg/d for 4Chronic weeks and Gentamicin 3 unknown 1 et 2bacteremias mg/kg/d for 2 weeksErythromycin 2A n g i o m a t o s e Erythromycine 2 g/d for 3g / d f o r 3bacillaire monthsmonths3Erythromycin 2Erythromycin 2 g/d for 4Hepatic peliosis g / d f o r 4monthsmonths3
EndocarditisGentamicin 3 mg/kg/d for 3weeks and amoxicillin 12 g/unknown 4d for 6 weeks or doxycyclin200 mg/d for 6 weeksReferences1. Bass, J. W., J. M. Vincent, and D. A. Person. 1997. Theexpanding spectrum of <strong>Bartonella</strong> infections: I. Bartonellosisand trench fever. Pediat.Inf.Dis.J. 16:2-10.2. Foucault, C., D. Raoult, and P. Brouqui. 2003. Randomizedopen trial of gentamicin and doxycycline for eradication of<strong>Bartonella</strong> <strong>quintana</strong> from blood in patients with chronicbacteremia. Antimicrob.Agents Chemother. 47:2204-2207.3. Koehler, J. E. and J. W. Tappero. 1993. Bacillaryangiomatosis and bacillary peliosis in patients infected withhuman immunodeficiency virus. Clin.Infect.Dis. 17 :612-624.4. Raoult, D., P. E. Fournier, F. Vandenesch, J. L. Mainardi, S. J.Eykyn, J. Nash, E. James, C. Benoit-Lemercier, and T. J.Marrie. 2003. Outcome and treatment of bartonellaendocarditis. Arch.Intern.Med. 163:226-230.5. Rolain, J. M., P. Brouqui, J. E. Koehler, C. Maguina, M. J.Dolan, and D. Raoult. 2004. Recommendations for treatmentof human infections caused by <strong>Bartonella</strong> species.Antimicrob.Agents Chemother. 48:1921-1933.16. Is it possible to prevent thedisease ?The prevention of B. <strong>quintana</strong> infections in the homelesspopulation relies on the eradication of body lice infestation.Treatment of human body lice infestation, also calledPediculosis relies on the complete change of all wornclothes, or on the use of insecticides such as DDT. Thosesmethods do not prevent reinfestations in situation whenpromiscuity is prevalent, such as in homeless shelters.
- Page 1 and 2: Bartonella quintanaUpdate: 17-10-20
- Page 4 and 5: References1. Maurin M, Raoult D. Ba
- Page 7 and 8: chronic bacteremia, bacteria circul
- Page 9 and 10: References1. Koehler JE, Sanchez MA
- Page 11 and 12: References1. Maurin, M., F. Eb, J.
- Page 13 and 14: Cutaneous lesions of bacillary angi
- Page 15 and 16: 12. CultureBacteria of the genus Ba
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- Page 21 and 22: 16s-23 sAll Bartonella F QHVE1space
- Page 23 and 24: All Bartonella groELF BbHs233. CGTG
- Page 25 and 26: two serotypes of Bartonella hensela
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- Page 31 and 32: 51.Maurin M, Birtles R, Raoult D. C
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