Bartonella quintana

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References1. Maurin M, Raoult D. Bartonella (Rochalimaea) quintanainfections. Clin Microbiol Rev 1996;9:273-92.2. Alsmark CM, Frank AC, Karlberg EO, Legault BA, Ardell DH,Canback B et al. The louse-borne human pathogenBartonella quintana is a genomic derivative of the zoonoticagent Bartonella henselae. Proc.Natl.Acad.Sci.U.S.A 2004;101:9716-21.4. Frequency / risk factorsBody lice infestation is the condition allowing thetransmission of B. quintana. Cold weather, poverty, lack ofhygiene are risk factors for body louse infestation. B.quintana infection develops when those conditions aregathered, which is the case during wars, in refugee camps,and in the homeless population.The frequency of B. quintana infection in the generalpopulation is unknown. Many epidemiological studies havebeen performed in the homeless population. In Marseilles,France, a study performed among 930 homelessdemonstrated that 7.5% of them have previously been incontact with the bacterium (presence of antibodies), and that5.3% of them were bacteremic (presence of bacterium in
circulating blood). The transmission of B. quintana by thehuman body louse is probably not the only way. Thebacterium has been detected in cat flies, and in patients withchronic adenopathy, suggesting a transmission mode closeto the cat scratch disease.Références1. Raoult D, Ndihokubwayo JB, Tissot-Dupont H, et al. Outbreakof epidemic typhus associated with trench fever in Burundi.Lancet 1998; 352:353-8.2. Foucault C, Barrau K, Brouqui P, Raoult D. Bartonellaquintana bacteremia among homeless people. Clin Infect Dis2002; 35:684-9.3. Brouqui P, Stein A, Tissot-Dupont H, Gallian P, Badiaga S,Rolain JM, Mege JL, La Scola B, Berbis P, and Raoult D.Ectoparasitism and Vector-Borne Diseases in 930 HomelessPeople from Marseilles. Medicine (Baltimore) 2005;84(1):1-8.4. Rolain JM, Franc M, Davoust B, Raoult D. Moleculardetection of Bartonella quintana, B. koehlerae, B. henselae,B. clarridgeiae, Rickettsia felis, and Wolbachia pipientis in catfleas, France. Emerg.Infect.Dis. 2003; 9(3):338-42.5. Raoult D, Drancourt M, Carta A, Gastaut JA. Bartonella(Rochalimaea) quintana isolation in patient with chronicadenopathy, lymphopenia, and a cat. Lancet 1994; 343:977.5. Clinical features (body lice)B. quintana infection must be evoked in subjects infested byhuman body lice. Pediculosis is frequently denied and canthus not be searched be questioning the patient. Body licemust be searched in clothes (T-shirts, underwear, socks) andis the best way to diagnose pediculosis. The simplest way isto look for scratching lesions, typically retrieved in the neck,the thorax and the ankles.Picture 3 Body lice in clothes
Page 1 and 2: Bartonella quintanaUpdate: 17-10-20
Page 7 and 8: chronic bacteremia, bacteria circul
Page 9 and 10: References1. Koehler JE, Sanchez MA
Page 11 and 12: References1. Maurin, M., F. Eb, J.
Page 13 and 14: Cutaneous lesions of bacillary angi
Page 15 and 16: 12. CultureBacteria of the genus Ba
Page 17 and 18: nodes of patients with cat scratch
Page 19 and 20: EndocarditisGentamicin 3 mg/kg/d fo
Page 21 and 22: 16s-23 sAll Bartonella F QHVE1space
Page 23 and 24: All Bartonella groELF BbHs233. CGTG
Page 25 and 26: two serotypes of Bartonella hensela
Page 27 and 28: 12.Rolain JM, Arnoux D, Parzy D, Sa
Page 29 and 30: 31.Lepidi H, Fournier PE, Raoult D.
Page 31 and 32: 51.Maurin M, Birtles R, Raoult D. C
Page 33: • Heparinized blood• Blood cult

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