#06-5558 Accrd Manual V7 - COLA

IMMUNOHEMATOLOGY & TRANSFUSION SERVICESTS 30 EAre anti-human globulin (AHG) reagents (Coombs serum) checked with positive and negative controls each dayof use and are the results documented?Test AHG routinely for IgG only. Anti-complement activity may be checked against complement-coated RBC’sif desired, but is not required. QC for AHG can be performedin one of the following ways:• React AHG with a presensitized reagent red blood cell which may be prepared commercially or by thelaboratory.• Use a known antibody which is demonstrated by the addition of AHG.• Add a presensitized reagent red blood cell to all negative antiglobulin tests to indicate that antiglobulinserum present in the test was not inactivated by unbound globulins or diluted by excess residual saline;therefore, negative results reflect true absence of reactivity. (Using green antiglobulin serum does notsubstitute for this control.)Recipient Testing for TransfusionTS 31RFor Allogenic Transfusions:Are pre-transfusion immunohematology specimens for testing of recipient’s blood obtained within 3 days of theanticipated transfusion if the patient’s history is not known or there is evidence of pregnancy or transfusionwithin the last 3 months in accordance with laboratory policies?> NOTE: The specimens used for this testing must accurately represent the patient’s serologic status at the timeof transfusion. If there is no evidence of recent immunologic stimulus, i.e. transfusion or pregnancy,the time frame between specimen collection and transfusion is not critical. The laboratory must documentand retain verification in the patient’s history records that the transfusion and pregnancy history wereverified. The laboratory must have a policy defining acceptable specimen collection dates for transfusionbased on the patient’s transfusion and/or pregnancy history. Time limits do not necessarily apply topatients receiving autologous transfusions unless they have a history of transfusion or pregnancy inthe past 3 months or allogenic transfusions are begun after the first specimen is obtained.The day the recipient’s specimen is obtained is day 0. The transfusion should be administered priorto the conclusion of day 3 and/or per established time limits for specimen use if there have been notransfusions and/or pregnancies in the prior three months. If the recipient’s transfusion or pregnancyhistory is unknown or the recipient has received one or more units since r the initial specimen wasdrawn, a new specimen must be obtained at the conclusion of day 3.68. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .FOR MORE INFORMATION CONTACT COLA PHONE 800.981.9883 | FAX 410.381.8611 | ON-LINE www.cola.org