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Familial Nasopharyngeal Carcinoma 6

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132 J-C. LinHwang CF, Cho CL, Huang CC, Wang JS, Shih YL, Su CY, ChangHW (2002) Loss of cyclin D1 and p16 expression correlateswith local recurrence in nasopharyngeal carcinoma followingradiotherapy. Ann Oncol 13:1246–1251Jahr S, Hentze H, Englisch S, Hardt D, Fackelmayer FO, Hesch RD,Knippers R (2001) DNA fragments in the blood plasma ofcancer patients: quantitations and evidence for their originfrom apoptotic and necrotic cells. Cancer Res 61:1659–1665Jian JJ, Cheng SH, Prosnitz LR, Tsai SY, Tsai MJ, Huang AT(1998) T classification and clivus margin as risk factors fordetermining locoregional control by radiotherapy ofnasopharyngeal carcinoma. Cancer 82:261–267Jian JJ, Cheng SH, Tsai SY, Yen KC, Chu NM, Chan KY, Tan TD,Cheng JC, Lin YC, Leu SY, Hsieh CI, Tsou MH, Lin CY, HuangAT (2002) Improvement of local control of T3 and T4nasopharyngeal carcinoma by hyperfractionated radiotherapyand concomitant chemotherapy. Int J Radiat OncolBiol Phys 53:344–352Jiong L, Berrino F, Coebergh JW (1998) Variation in survivalfor adults with nasopharyngeal cancer in Europe, 1978–1989. Eur J Cancer 34:2162–2166Johansen LV, Grau C, Overgaard J (2001) Squamous cell carcinomaof the nasopharynx – an analysis of treatment resultsin 149 consecutive patients. Acta Oncol 40:801–809Kalogera-Fountzila A, Karanikolas D, Katodritis N, Samantas E,Sarafopoulos A, Ikonomou I, Zamboglou N, Tselis N,Dimitriadis AS, Fountzila G (2006) Prognostic factors andsignificance of the revised 6th edition of the AJCC classificationin patients with locally advanced nasopharyngeal carcinoma.Strahlenther Onkol 182:458–466Kam MK, Teo PM, Chau RM, Cheung KY, Choi PH, Kwan WH,Leung SF, Zee B, Chan AT (2004) Treatment of nasopharyngealcarcinoma with Intensity-modulated radiotherapy:the Hong Kong experience. Int J Radiat Oncol Biol Phys60:1440–1450Khademi B, Mahmoodi J, Omidvari S, Mohammadianpanah M(2006) Treatment results of nasopharyngeal carcinoma: a15-year single institutional experience. J Egypt Natl CancerInst 18:147–155Kim JH, Lee JK (2005) Prognostic value of tumor volume innasopharyngeal carcinoma. Yonsei Med J 46:221–227King AD, Lam WW, Leung SF, Chan YL, Teo P, Metreweli C(1999) MRI of local disease in nasopharyngeal carcinoma:tumor extent vs tumor stage. Br J Radiol 72:734–741King AD, Teo P, Lam WW, Leung SF, Metreweli C (2000)Paranasopharyngeal space involvement in nasopharyngealcancer: detection by CT and MRI. Clin Oncol (R CollRadiol) 12:397–402Krishna SM, James S, Balaram P (2006) Expression of VEGF asprognosticator in primary nasopharyngeal cancer and itsrelation to EBV status. Virus Res 115:85–90Kwong DL, Pow EH, Sham JS, McMillan AS, Leung LH, LeungWK, Chua DT, Cheng AC, Wu PM, Au GK (2004a) Intensitymodulatedradiotherapy for early-stage nasopharyngealcarcinoma: a prospective study on disease control andpreservation of salivary function. Cancer 101:1584–1593Kwong DL, Sham JS, Au GK, Chua DT, Kwong PW, Cheng AC,Wu PM, Law MW, Kwok CC, Yau CC, Wan KY, Chan RT,Choy DD (2004b) Concurrent and adjuvant chemotherapyfor nasopharyngeal carcinoma: a factorial study. J ClinOncol 22:2643–2653Kwong DL, Sham JS, Leung LH, Cheng AC,Kwong PW, Lui WM,Yau CC, Wu PM, Wei W, Au G (2006) Preliminary results ofradiation dose escalation for locally advanced nasopharyngealcarcinoma. Int J Radiat Oncol Biol Phys 64:374–381Lam WWM, Chan YL, Leung SF, Metreweli C (1997)Retropharyngeal lymphadenopathy in nasopharyngealcarcinoma. Head Neck 19:176–181Langendijk JA, Leemans CR, Buter J, Berkhof J, Slotman BJ(2004) The additional value of chemotherapy to radiotherapyin locally advanced nasopharyngeal carcinoma: ameta-analysis of the published literature. J Clin Oncol22:4604–4612Le QT, Jones CD, Yau TK, Shirazi HA, Wong PH, Thomas EN,Patterson BK, Lee AW, Zehnder JL (2005) A comparisonstudy of different PCR assays in measuring circulatingplasma Epstein–Barr virus DNA levels in patients withnasopharyngeal carcinoma. Clin Cancer Res 11:5700–5707Lee AW, Foo W, Law SC, Poon YF, SK O, Tung SY, Sze WM,Chappell R, Lau WH, Ho JH (1999) Staging of nasopharyngealcarcinoma: from Ho’s to the new UICC system. Int JCancer 84:179–187Lee AW, Sze WM, Yau TK, Yeung RMW, Chappell R, Fowler JF(2001) Retrospective analysis of treating nasopharyngealcarcinoma with accelerated fractionation (6 fractions perweek) in comparison with conventional fractionation (5fractions per week): report on 3-year tumor control andnormal tissue toxicity. Radiother Oncol 58:121–130Lee AW, Au JS, Teo PM, Leung TW, Chua DT, Sze WM, Zee BC,Law SC, Leung SF, Tung SY, Kwong DL, Lau WH (2004)Staging of nasopharyngeal carcinoma: suggestions forimproving the current UICC/AJCC staging system. ClinOncol 16:269–276Lee AW, Lau WH, Tung SY, Chua DT, Chappell R, Xu L, Siu L,Sze WM, Leung TW, Sham JS, Ngan RK, Law SC, Yau TK, AuJS, O’Sullivan B, Pang ES, SK O, Au GK, Lau JT; Hong Kong<strong>Nasopharyngeal</strong> Cancer Study Group (2005a) Preliminaryresults of a randomized study on therapeutic gain by concurrentchemotherapy for regionally-advanced nasopharyngealcarcinoma: NPC-9901 trial by the Hong Kong<strong>Nasopharyngeal</strong> Cancer Study Group. J Clin Oncol 23:6966–6975Lee AW, Sze WM, Au JS, Leung SF, Leung TW, Chua DT, Zee BC,Law SC, Teo PM, Tung SY, Kwong DL, Lau WH (2005b)Treatment results for nasopharyngeal carcinoma in themodern era: the Hong Kong experience. Int J Radiat OncolBiol Phys 61:1107–1116Lee AW, Tung SY, Chan AT, Chappell R, Fu YT, Lu TX, Tan T,Chua DT, O’sullivan B, Xu SL, Pang ES, Sze WM, Leung TW,Kwan WH, Chan PT, Liu XF, Tan EH, Sham JS, Siu L, LauWH (2006) Preliminary results of a randomized study(NPC-9902 trial) on therapeutic gain by concurrent chemotherapyand/or accelerated fractionation for locallyadvanced nasopharyngeal carcinoma. Int J Radiat OncolBiol Phys 66:142–151Lee CC, Ho HC, Lee MS, Hsiao SH, Hwang JH, Hung SK, Chou P(2008) Primary tumor volume of nasopharyngeal carcinoma:significance for survival. Auris Nasus Larynx 35:376–380Lee JT, Ko CY (2005) Has survival improved for nasopharyngealcarcinoma in the United States? Otolaryngol HeadNeck Surg 132:303–308Lee N, Xia P, Quivey JM, Sultanem K, Poon I, Akazawa C,Akazawa P, Weinberg V, Fu KK (2002) Intensity-modulatedradiotherapy in the treatment of nasopharyngeal carcinoma:an update of the UCSF experience. Int J Radiat OncolBiol Phys 53:12–22

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