Familial Nasopharyngeal Carcinoma 6

278 S. S. Lo, J. J. Lu, and L. KongTable 22.2. Detal caries secondary to radiation therapyRTOG-EORTC scoring criteria for late radiation-induced salivarygland morbidity (Nicolatou-Galitis et al. 2003)GradeCriteria0 None1 Slight dryness of mouth with good responseto stimulation2 Moderate dryness of mouth with poorresponse to stimulation3 Complete dryness of mouth with noresponse to stimulation4 FibrosisTable 22.3. CTCAE v3.0 scoring criteria for xerostomia( Koukourakis 2002; Eisbruch et al. 1999)GradeCriteria0 None1 Symptomatic (dry or thick saliva) withoutsignificant dietary alteration; unstimulatedsaliva flow >0.2 ml/min2 Symptomatic and significant oral intakealteration (e.g., copious water, other lubricants,diet limited to purees and/or soft, moist foods);unstimulated saliva 0.1–0.2 ml/min3 Symptoms leading to inability to adequatelyaliment orally; IV fluids, tube feedings, or TPNindicated; unstimulated saliva