Abstracts Poster Abstracts - Dr Falk

76Epidemiological analysis of HBV, HCV infections in patients withdermatological diseasesMariana Malczyk, V. LunguGastroenterology Department - Algomed Clinic Timisoara, RomaniaIntroduction: Detection of HBV, HCV infections in a group of patients withdermatological diseases, assessing the prevalence of HBsAg and HCV Ab andepidemiological analysis of the risk factors.Methods: We investigated a group of 322 patients with dermatological diseases, andanother group of 302 patients without dermatological diseases concerning theseroprevalence of HBsAg and HCV Ab. We used the enzyme immunoassay (ELISA)for detection of HBsAg and HCV Ab and the Epiinfo program for the analysis ofepidemiological factors (sexual, parenteral, surgical, transfusional). As a epidemiologicalmethods we used descriptive analysis and case-control study.Results: The seroprevalence of HBsAg was 11.8% in the case lot and 5.5% in thecontrol lot (p < 0.001, OR: 2.13). The mean of age was 45 and the difference betweenmale and female was insignificant. The seroprevalence of HCV Ab was 12.4% in thecase lot and 1.6% in the control lot (p < 0.0001, OR: 7.62). The analysis ofepidemiological factors in HBV, HCV infections, showed an association of 2 factors inup to 60% of cases. Sexual risk was present in 13.2% of HBV-positive cases and 11%of HCV Ab-positive cases. Parenteral risk was present in 21% of HBV-positive subjectsand 31% in HCV Ab-positive subjects. Surgical risk was positive in 18% of HBV casesand 40% of HCV Ab-positive cases. Concerning the transfusion, just 17.5% of HCV Abpositivesubjects had a history of transfusion.Discussion/Conclusion: Our study shows an increased prevalence of HBV and HCVinfection in patients with dermatological disorders compared with the general population(p < 0.0001). This situation asks for a continuous monitoring of these infections, theimprovement of sexual educations methods and further studies on this subject.