Abstracts Poster Abstracts - Dr Falk

89Biliary atresia in Republic Sakha (Yakutia)E. Pavlova 1 , M. Ohlopkov 2 , V. Savina 2 , V. Nikolaev 21 Yakutsk Research Center, Russia2 Department of Surgery, National Center of Medicine of Republic Sakha (Yakutia),RussiaAim: To evaluate the clinical presentation, complications and outcome of infants withbiliary atresia.Methods: Retrospective chart analysis of medical records of infants with biliary atresiawas made for period 1999-2004.Results: A total of 9 patients were studied, 4 pts (44%) diagnostic over last year. Therewere 8 boys and 1 girl. The median age of presentation was 60 days (range 40-90days). Infection of cytomegalovirus was found in 8 patients (89%). In 44% cases (4 pts)was intrahepatic biliary atresia, in 64% cases - extrahepatic biliary atresia. All cases isnon-syndromic the biliary atresia. The same surgical team performed Kasai operationon 7 infants (hepatic portoenterostomy: 5 pts, hepatic portocholecystostomy: 2 pts). Themedian age at time of operation was 66 days after birth (range 47-106 days). 6 pts hadno drainage and 1 patient had good drainage. Among the 6 patients with no drainagehad died, 4 pts with biliary cirrhosis is on the waiting list for liver transplantation. Themedian age when the patient became jaundice-free was 2 months of age (range 1-3months). Complications included cholangitis (22%), portal hypertension (44%). The ageat surgery did not significantly influence the outcome of the patients.Conclusions: Incidence of biliary atresia increased over last 1 year and composed4:14000 live births in Yakutia. In 89% cases was founded association of biliary atresiawith cytomegalovirus infection. Liver transplantation is the complementary therapyoption in 60% patients.