Analytical Chem istry - DePauw University

13. Kinetic Methods .. . . . . . . . . . . . . . . . . . . . . . . . . . . 88113A Kinetic Methods Versus Equilibrium Methods . . . . . . . . . . . . . . . .88213B Chemical Kinetics ......................................88313B.1 Theory and Practice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88313B.2 Classifying Chemical Kinetic Methods ..............................88613B.3 Making Kinetic Measurements ....................................89613B.4 Quantitative Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89813B.5 Characterization Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90113B.6 Evaluation of Chemical Kinetic Methods ............................904Accuracy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90513C Radiochemistry ........................................90813C.1 Theory and Practice ............................................90913C.2 Instrumentation ...............................................90913C.3 Quantitative Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91013C.4 Characterization Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91413C.5 Evaluation ...................................................91513D Flow Injection Analysis ..................................91613D.1 Theory and Practice ............................................91613D.2 Instrumentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92013D.3 Quantitative Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92413D.4 Evaluation ...................................................92813E Key Terms ............................................92913F Summary .............................................92913G Problems .............................................93013H Solutions to Practice Exercises .............................93914. Developing a Standard Method................94114A Optimizing the Experimental Procedure .....................94214A.1 Response Surfaces . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94214A.2 Searching Algorithms for Response Surfaces ..........................94314A.3 Mathematical Models of Response Surfaces . . . . . . . . . . . . . . . . . . . . . . . . . . 95014B Verifying the Method ....................................96014B.1 Single Operator Characteristics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96014B.2 Blind Analysis of Standard Samples . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96114B.3 Ruggedness Testing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96114B.4 Equivalency Testing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96414C Validating the Method as a Standard Method .................96514C.1 Two-Sample Collaborative Testing .................................96514C.2 Collaborative Testing and Analysis of Variance ........................97014C.3 What is a Reasonable Result for a Collaborative Study? .................97614D Using Excel and R for an Analysis of Variance .................97714D.1 Excel .......................................................977