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Program Book - Keck School of Medicine of USC - University of ...

Program Book - Keck School of Medicine of USC - University of ...

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Vascular Access Surveillance• Observational studies vs RandomizedControlled Trials• Obs-comparing against historical controls• Introduce bias• RCT reduce bias and causalityRefVascular Access SurveillanceObservational StudiesSurveillancemethodThrombosis rate (per graft years)Historical Surveillance % ReductionSchwab DVP 0.61 0.20 67Besarab Static VP 0.50 0.28 64Safa CM 0.48 0.17 64Allon CM 0.70 0.28 60Cayco CM 0.49 0.29 41McCarley Flow Monitoring 0.71 0.16 77Vascular Access SurveillanceRandomized Controlled Trials• Total <strong>of</strong> 12 RCT• AVG-8• AVF-4• Sample sizes ranged from 51-189 pts• Followup ranged from 6-28 months• They differ in sample sizes, method <strong>of</strong> surveillance,recruitment criteria72

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