ANZCA Bulletin June 2012 - final.pdf - Australian and New Zealand ...

ANZCA Trials Group meetsat the annual scientificmeeting in PerthPerth meetingOne of the important core activities forthe ANZCA Trials Group is the annualscientific meeting. This year, the Perthmeeting included two trials groupscientific sessions, the annual trials grouplunchtime meeting and a trials groupexecutive committee meeting.For the first time since the 2011 PalmCove research workshop, the newlyformed ANZCA Research Co-ordinators’– Special Interest Group (ARC-SIG) metat lunchtime on May 12 at the PerthExhibition and Conference Centre. The 11participants, led by Sofia Sidiropoulos,discussed terms of reference for futuremeetings and a program for the breakoutsessions for the forthcoming ANZCA TrialsGroup Strategic Research Workshop inPalm Cove on August 10-12.All co-ordinators were partiallysupported to attend by the NationalHealth and Medical Research Councilgrant for the Peri-operative IschaemicEvaluation-2 Trial (POISE-2 trial).Associate Professor David Storychaired the first ANZCA Trials Groupscientific session on Saturday morning.Professor Steve Webb, the chair of theAustralian and New Zealand IntensiveCare Society-Clinical Trials Group(ANZICS-CTG), opened the sessionwith a talk on what is new in intensivecare research. Professor Matthew Chanfollowed with a presentation on hiswork with the neuro-vision pilot study.Professor Julia Fleming wrapped up thesession with a presentation on intraguanethidinefor Raynaud’s syndrome:a pilot study. Both Professors Chan andFleming were recipients of the ANZCATrials Group Pilot Grant Scheme, andwere awarded grants of $5000 last year.The chair of the ANZCA Trials Group,Associate Professor Tim Short, chairedthe second session, “Methods andmadness in clinical trials”, on Tuesdayafternoon. Professor Paul Myles gave aninformative talk on equipoise in clinicalresearch. Professor Myles was followedby Dr Nolan Mc Donnell, who demystifiedthe mysterious with a presentationon superiority, non-inferiority andequivalence trials.The ANZCA Trials Group sessionsat the annual scientific meeting followan update/methodology/results formatand Professor Stephen Schug finishedthe session with a presentation onmeasurement tools in acute pain research:is there room for improvement?The annual ANZCA Trials Grouplunchtime meeting followed and wasattended by more than 30 participantsfrom Australia, New Zealand and HongKong, including research co-ordinatorsassociated with trials group research.Professor Tim Short chaired the meeting.Professor Myles opened the discussionon how future research could be betterfunded especially for investigatorinitiatedresearch, as well as updating theattendees on research activity associatedwith ANZCA multicentre research.Most of the lunchtime meeting wasassigned to a POISE-2 investigatormeeting, chaired by the national coordinatorfor Australia and New Zealand,Professor Kate Leslie. She informed themeeting that POISE-2 is engaged with 33sites across Australia, 10 are activated and27 patients have been recruited to date.Professor Leslie thanked the investigatorsand co-ordinators at the meeting fortheir hard work and persistence ingetting POISE-2 up and running in adifficult research environment. TheRoyal Adelaide Hospital (Dr TomPainter and Sue Lang, and colleagues)was identified as having made anoutstanding contribution to POISE-2,with 16 patients recruited to date. Thissite is also the largest contributor to theAspirin and Tranexamic Acid for CoronaryArtery Surgery Trial (ATACAS Trial).Congratulations to Tom and Sue andtheir colleagues!Pilot grantsThe ANZCA Trials Group is pleased toannounce that the first pilot grant of$A5000 for 2012 has been awarded toDr Ben Olesnicky, Royal North ShoreHospital, NSW, for his project “Effectof Analgesic Regime on OutcomesFollowing Major Hepatobiliary Surgery– A Comparison of Epidural Analgesiaand Intrathecal Morphine”.For more information of the ANZCAPilot Grant Scheme, which is open toapplicants all year, see: www.anzca.edu.au/fellows/Research/trials-group/pilotgrant-scheme.htmlPublicationsLeslie K, Myles PS, Chan MTV, Forbes A,Paech M, Peyton P, Silbert BS, WilliamsonE. Nitrous oxide and long-term morbidityand mortality in the ENIGMA Trial.Anesth Analg 2011; 112:387-393.Graham AM, Myles PS, Leslie K, Chan MT,Paech MJ, Peyton P, E I Dawlatly AA. Acost-benefit analysis of the ENIGMA trial.Anesthesiology 2011 Aug;115(2):265-72Myles PS; the ENIGMA Trial Investigators.Correspondence. Anesthesiology. 2012Mar; 116(3):736Leslie K. Myles P.S. Halliwell R. PaechM.J. Short T.G. Walker S. Beta-blockermanagement in high-risk patientspresenting for non-cardiac surgery: Beforeand after the POISE Trial. Anaesthesiaand Intensive Care 2012; 40(2): 319-327.46 ANZCA Bulletin June 2012