<strong>ANZCA</strong> Trials Group meetsat the annual scientificmeeting in PerthPerth meetingOne of the important core activities forthe <strong>ANZCA</strong> Trials Group is the annualscientific meeting. This year, the Perthmeeting included two trials groupscientific sessions, the annual trials grouplunchtime meeting <strong>and</strong> a trials groupexecutive committee meeting.For the first time since the 2011 PalmCove research workshop, the newlyformed <strong>ANZCA</strong> Research Co-ordinators’– Special Interest Group (ARC-SIG) metat lunchtime on May 12 at the PerthExhibition <strong>and</strong> Conference Centre. The 11participants, led by Sofia Sidiropoulos,discussed terms of reference for futuremeetings <strong>and</strong> a program for the breakoutsessions for the forthcoming <strong>ANZCA</strong> TrialsGroup Strategic Research Workshop inPalm Cove on August 10-12.All co-ordinators were partiallysupported to attend by the NationalHealth <strong>and</strong> Medical Research Councilgrant for the Peri-operative IschaemicEvaluation-2 Trial (POISE-2 trial).Associate Professor David Storychaired the first <strong>ANZCA</strong> Trials Groupscientific session on Saturday morning.Professor Steve Webb, the chair of the<strong>Australian</strong> <strong>and</strong> <strong>New</strong> Zeal<strong>and</strong> IntensiveCare Society-Clinical Trials Group(ANZICS-CTG), opened the sessionwith a talk on what is new in intensivecare research. Professor Matthew Chanfollowed with a presentation on hiswork with the neuro-vision pilot study.Professor Julia Fleming wrapped up thesession with a presentation on intraguanethidinefor Raynaud’s syndrome:a pilot study. Both Professors Chan <strong>and</strong>Fleming were recipients of the <strong>ANZCA</strong>Trials Group Pilot Grant Scheme, <strong>and</strong>were awarded grants of $5000 last year.The chair of the <strong>ANZCA</strong> Trials Group,Associate Professor Tim Short, chairedthe second session, “Methods <strong>and</strong>madness in clinical trials”, on Tuesdayafternoon. Professor Paul Myles gave aninformative talk on equipoise in clinicalresearch. Professor Myles was followedby Dr Nolan Mc Donnell, who demystifiedthe mysterious with a presentationon superiority, non-inferiority <strong>and</strong>equivalence trials.The <strong>ANZCA</strong> Trials Group sessionsat the annual scientific meeting followan update/methodology/results format<strong>and</strong> Professor Stephen Schug finishedthe session with a presentation onmeasurement tools in acute pain research:is there room for improvement?The annual <strong>ANZCA</strong> Trials Grouplunchtime meeting followed <strong>and</strong> wasattended by more than 30 participantsfrom Australia, <strong>New</strong> Zeal<strong>and</strong> <strong>and</strong> HongKong, including research co-ordinatorsassociated with trials group research.Professor Tim Short chaired the meeting.Professor Myles opened the discussionon how future research could be betterfunded especially for investigatorinitiatedresearch, as well as updating theattendees on research activity associatedwith <strong>ANZCA</strong> multicentre research.Most of the lunchtime meeting wasassigned to a POISE-2 investigatormeeting, chaired by the national coordinatorfor Australia <strong>and</strong> <strong>New</strong> Zeal<strong>and</strong>,Professor Kate Leslie. She informed themeeting that POISE-2 is engaged with 33sites across Australia, 10 are activated <strong>and</strong>27 patients have been recruited to date.Professor Leslie thanked the investigators<strong>and</strong> co-ordinators at the meeting fortheir hard work <strong>and</strong> persistence ingetting POISE-2 up <strong>and</strong> running in adifficult research environment. TheRoyal Adelaide Hospital (Dr TomPainter <strong>and</strong> Sue Lang, <strong>and</strong> colleagues)was identified as having made anoutst<strong>and</strong>ing contribution to POISE-2,with 16 patients recruited to date. Thissite is also the largest contributor to theAspirin <strong>and</strong> Tranexamic Acid for CoronaryArtery Surgery Trial (ATACAS Trial).Congratulations to Tom <strong>and</strong> Sue <strong>and</strong>their colleagues!Pilot grantsThe <strong>ANZCA</strong> Trials Group is pleased toannounce that the first pilot grant of$A5000 for <strong>2012</strong> has been awarded toDr Ben Olesnicky, Royal North ShoreHospital, NSW, for his project “Effectof Analgesic Regime on OutcomesFollowing Major Hepatobiliary Surgery– A Comparison of Epidural Analgesia<strong>and</strong> Intrathecal Morphine”.For more information of the <strong>ANZCA</strong>Pilot Grant Scheme, which is open toapplicants all year, see: www.anzca.edu.au/fellows/Research/trials-group/pilotgrant-scheme.htmlPublicationsLeslie K, Myles PS, Chan MTV, Forbes A,Paech M, Peyton P, Silbert BS, WilliamsonE. Nitrous oxide <strong>and</strong> long-term morbidity<strong>and</strong> mortality in the ENIGMA Trial.Anesth Analg 2011; 112:387-393.Graham AM, Myles PS, Leslie K, Chan MT,Paech MJ, Peyton P, E I Dawlatly AA. Acost-benefit analysis of the ENIGMA trial.Anesthesiology 2011 Aug;115(2):265-72Myles PS; the ENIGMA Trial Investigators.Correspondence. Anesthesiology. <strong>2012</strong>Mar; 116(3):736Leslie K. Myles P.S. Halliwell R. PaechM.J. Short T.G. Walker S. Beta-blockermanagement in high-risk patientspresenting for non-cardiac surgery: Before<strong>and</strong> after the POISE Trial. Anaesthesia<strong>and</strong> Intensive Care <strong>2012</strong>; 40(2): 319-327.46 <strong>ANZCA</strong> <strong>Bulletin</strong> <strong>June</strong> <strong>2012</strong>
Events4th Annual Strategic ResearchWorkshop, Sea Temple, Palm Cove,Qld, August 10-12.Following a very successful workshopmeeting in Palm Cove in 2011, the <strong>ANZCA</strong>Trials Group is returning to Palm Covefor its 4th annual consecutive meetingthis year. The workshops bring togetherexperienced researchers as well as new<strong>and</strong> emerging researchers from Australia,<strong>New</strong> Zeal<strong>and</strong> <strong>and</strong> Hong Kong. Thesemeetings aim to present, mentor <strong>and</strong>encourage new ideas for multicentreresearch in anaesthesia, perioperative<strong>and</strong> pain medicine. Participants receiveupdates about existing research <strong>and</strong> areencouraged to engage in multicentretrials.We also encourage anaesthesiaresearch nurses <strong>and</strong> co-ordinators toattend.<strong>ANZCA</strong> Research Co-ordinators’ –Special Interest Group (ARC-SIG) hasinvited the <strong>Australian</strong> <strong>and</strong> <strong>New</strong> Zeal<strong>and</strong>Intensive Care Society-Clinical TrialsGroup (ANZICS-CTG) Research Coordinators– Special Interest Group chair,Rachael Parke, from Auckl<strong>and</strong>, to presentat one of the breakout sessions.Associate Professor Steve Webb, thechair of the ANZICS-CTG, is a guestspeaker along with biostatisticianDr Katherine Lee from the ClinicalEpidemiology <strong>and</strong> Biostatistical Unit,Murdoch Children’s Research InstituteMelbourne. There will also be a POISE-2trial investigators’ meeting.Participants are encouraged to bringalong their ideas for future multicentreresearch. Please contact spoustie@anzca.edu.au prior to the workshop with thetitle <strong>and</strong> a one-page summary of yourproposal(s).More information can be found at:www.anzca.edu.au/fellows/Research/anzca-trials-group-events.htmlStephanie Poustie<strong>ANZCA</strong> Trials GroupResearch Fellow <strong>and</strong> Co-ordinator8th ISHA 2013ISHA 2013History Matters!‘The Anaesthetist’ by HaroldCazneaux 19338th International Symposium onthe History of Anaesthesia,22–25 January 2013, University of Sydney, AustraliaSatellite meeting, Melbourne, January 29-30Geoffrey Kaye Museum of Anaesthetic History, <strong>Australian</strong>& <strong>New</strong> Zeal<strong>and</strong> College of AnaesthetistsThe University of Sydneywww.isha2013.comisha2013@asa.org.au47