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CME/CE: PharmacologyAntibiotic Resistance • NPPA18Questions1. A new beta-lactamaseinhibitor, Ro 48-1220, has beenshown, in clinical trials, toimprove the activity of whichcephalosporin?a. Cetazidime (Fortax)b. Ceftriaxone (Rocephin)c. Cefotaxime (Claforan)d. Cefotetan (Cefotan)2. Which recently FDA approvedantibiotic cannot be used totreat pneumonia?a. Daptomycin (Cubicin)b. Tigecycline (Tigacil)c. Doripenem (Doribax)d. Telavancin (Vabativ)3. All but which one of thefollowing resistant organismshave been identified by the WHOas most concerning?a. Staphylococcus aureusb. Klebsiella pneumoniac. Streptococcus pneumoniad. Enterococcus faecium4. The Infectious DiseasesSociety of America haschallenged pharmaceuticalcompanies with developingwhich number of newantimicrobial agents by 2020?a. 5b. 10c. 15d. 205. Of the recently FDA-approvedantibiotics, which one can cause‘red man syndrome’ if infused toorapidly?a. Daptomycin (Cubicin)b. Tigecycline (Tigacil)c. Doripenem (Doribax)d. Telavancin (Vabativ)6. Which antibiotic is the onlyone recently approved by theFDA that has coverage forPseudomonas aeruginosa?a. Daptomycin (Cubicin)b. Tigecycline (Tigacil)c. Doripenem (Doribax)d. Telavancin (Vabativ)7. After mass production ofpenicillin began in 1943, bywhich year had resistancedeveloped?a. 1946b. 1947c. 1948d. 19498. A newly discovered betalactamaserenders Klebsiellaand E coli resistant to all of thefollowing antibiotic classesexcept:a. Aminoglycosidesb. Cephalosporinsc. Carbapenemsd. Fluoroquinolones9. Appropriate hand hygieneadherence typically occurs whatpercentage of the time whenproviders exit patient rooms?a. 69%b. 51%c. 48.4%d. 32%10. When examining an increasein MDRO infections in longtermcare facilities, one recentstudy isolated MRSA in whatpercentage of cultures?a. 1%b. 6%c. 11%d. 18%Evaluation1. The content was appropriatefor my needs.a. strongly disagreeb. disagreec. neutrald. agreee. strongly agree2. The educational objectiveswere achieved.a. strongly disagreeb. disagreec. neutrald. agreee. strongly agree3. The information provided waspractical and can be applied tomy professional needs.a. strongly disagreeb. disagreec. neutrald. agreee. strongly agree4. The information in the articlewas fair, balanced, free ofcommercial bias and supportedby scientific evidence.a. strongly disagreeb. disagreec. neutrald. agreee. strongly agreeRegistration & Answer FormThis activity has been planned and implemented in accordance with the Essential Areasand policies of the Accreditation Council for Continuing Medical Education through thejoint sponsorship of Wayne State University School of Medicine and ADVANCE for NPs& PAs. The Wayne State University School of Medicine is accredited by the ACCME toprovide continuing medical education for physicians.The Wayne State University School of Medicine designates this educational activityfor a maximum of 1 AMA PRA Category 1 Credit(s). Physicians should only claim creditcommensurate with the extent of their participation in the activity.This activity also is approved for 2 CE contact hours. The issuer of CE contact hoursis Merion Publications (a division of Merion Matters), which is approved as a provider ofcontinuing education in nursing by three agencies. For details on CE provider numbers,visit the CE Test Center on our website, www.advanceweb.com/NPPA.For PAs:To obtain CME credit, send the completed answer form and registrant informationto Wayne State University School of Medicine, Attn PA, University Health Center 9A,4201 Saint Antoine St., Detroit, MI 48201. Include a check for $10 payable to WayneState University. Or fax the completed form and credit card information to (313) 577-7554. Note: Discover and American Express NOT accepted. For online payment, visithttp://www.med.wayne.edu/cme/calendarReg.html. Test takers who earn a passingscore will receive a CME certificate by mail, or if paying online can receive an onlinetranscript once registered at http://www.med.wayne.edu/cme/calendarTran.html. Forquestions about CME, call Wayne State University at (313) 577-1453. CME form mustbe postmarked or received within 6 months of the last day of the month of this issue.For NPs:To obtain CE contact hours, take this test online at www.advanceweb.com/NPPA andreceive instant test results and a printable CE certificate upon passage. Or fax thecompleted form and credit card information to (610) 278-1426. Or send the completedanswer form and registrant information to Merion Matters CE Program for NPs, 2900Horizon Dr., King of Prussia, PA 19406. Include a check for $10 payable to MerionMatters. This activity is eligible for CE credit for 2 calendar years after publication.Antibiotic Resistance February 2012Test NPPA18EvaluationA B C D A B C D A B C D E1.2.3.4.5.6.7.8.9.10.1.2.3.4.Registrant Information (Please print)Subscriber No. (see mailing label) ____ ____ ____ ____ ____ ____ ____ ____ ____Required for Florida NPs: License No. ___________________________________________E-mail Address ______________________________________________________________Name ______________________________________________________________________Address ❏ Work ❏ Home ___________________________________________________City ____________________________________ State ______ Zip Code _______________Phone No. ❏ Work ❏ Home _________________________________________________Payment: $10❏ For PAs: Check Payable to Wayne State University❏ For NPs: Check Payable to Merion Matters❏ For PAs or NPs: Credit Card No. ________________________ Exp. Date___________Cardholder Name ________________________________________________________Signature _______________________________________________________________❏ American Express (NPs only) ❏ Visa ❏ MasterCard ❏ Discover (NPs only)Statement of CompletionI attest to having completed the CME/CE activity.Signature _____________________________________________ Date _________________Profession ❏ Nurse Practitioner ❏ Physician AssistantADVANCE for NPs & PAs29