Epigenetics - LSUHSC Human Development Center
Epigenetics - LSUHSC Human Development Center
Epigenetics - LSUHSC Human Development Center
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DNA methylation turns genes on or off• Non-methylated or hypomethylatedDNA sequences are usuallyexpressed• Highly methylated(hypermethylated) DNA sequencesare usually not expressedGeneHypo-MethylationHyper-MethylationTherefore,↑ DNA methylation, ↓gene expression↓ DNA methylation, ↑ gene expression