Epigenetics - LSUHSC Human Development Center
Epigenetics - LSUHSC Human Development Center
Epigenetics - LSUHSC Human Development Center
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Turning on of abnormallyinactivated tumor suppressorgenes5-aza-2′-deoxycytidine (also calledDecitabine) has both a hypomethylatingeffect at low doses when incorporated intoDNA and a cytotoxic effect at higher dosesas a result of interfering with translationwhen incorporated into RNA.Used for chemotherapy for leukemias.