Perioperative antibiotic prophylaxis in adults - Sistema Nazionale ...

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IndexSummary of the principal recommendationsGeneral principles of preventionList of principal recommendationsLocal implementation of the guidelineIntroductionBackgroundAims and recipients of antibiotic prophylaxisNeed for the guidelineNew features of the updated guidelineIssues addressed in the guidelineMethodsLiterature searchSelection criteria and tools for methodological assessmentLevels of evidence and grades of recommendationsExternal reviewNext update, diffusion, implementation and assessmentPerioperative antibiotic phophylaxis in adultsQuestion 1: What are the risk factors for surgical site infections and how do theyaffect the choice of antibiotic prophylaxis?Question 2: What are the benefits and risks of perioperative antibiotic prophylaxis?Question 3: In which operations has antibiotic prophylaxis been proved to reduce therisk of surgical site infections?Question 4: Which type of antibiotic is recommended for perioperative prophylaxis?How and when should it be administered?Implementation of the guidelineDevelopment of local guidelinesCompliance with measures for prevention recommended by the Centers for DiseaseControl and Prevention (CDC)
Implementation strategies most widely accredited in clinical studiesRecording of drugs administered and minimum data setKey points and core indicators for auditing application of the guidelineData set needed to audit perioperative antibiotic prophylaxisAnnexes1. Proposals for local implementation2. Recommendations for antibiotic prophylaxis in bacterial endocarditis3. Antibiotic prophylaxis in patients with prostheses or prosthetic devices4. CDC/NHSN criteria for the definition of SSI5. Classification of operations by duration >75 th percentile6. Micro-organisms most frequently associated with postoperative infections7. Auditing compliance with CDC rules for preventing SSIBibliography
Page 1 and 2: SNLG17Perioperative antibiotic prop
Page 3 and 4: Perioperative antibiotic prophylaxi
Page 5: In this regard, the website of the
Page 9 and 10: MULTIDISCIPLINARY PANELFulvio Calis
Page 11 and 12: Società Italiana di Ortopedia e Tr
Page 13: RCT: Randomised Clinical (controlle
Page 17 and 18: 1. Proper ventilation systems in th
Page 19 and 20: VI/B Clean-contaminated procedures
Page 21 and 22: # Radical prostatectomyRadical cyst
Page 23 and 24: I/A Antibiotic prophylaxis should b
Page 25 and 26: contact with the surgical field dur
Page 27 and 28: 3. Management of colonised or infec
Page 29 and 30: *measures strongly recommended and
Page 31 and 32: included (this issue has been marke
Page 33 and 34: possible, the evidence base for the
Page 35 and 36: The working group considered that t
Page 37 and 38: omission of more recent studies was
Page 39 and 40: particular circumstances. Nonethele
Page 41 and 42: Dirty:encountered or there is visib
Page 43 and 44: • the duration of surgery (when t
Page 45 and 46: colitis or diarrhoea. The prevalenc
Page 47 and 48: Where evidence of efficacy is avail
Page 49 and 50: (1-expected baseline risk) x expect
Page 51 and 52: Contamination of the operative site
Page 53 and 54: • exanthema (rash)Other less spec
Page 55 and 56: The steady increase in the frequenc
Page 57 and 58: impact is the same, preference shou
Page 59 and 60: II/A In most cases antibiotic proph
Page 61 and 62: For heart surgery performed with ex
Page 63 and 64: Implementation of the guidelineDeve
Page 65 and 66:
in the field, and the distribution
Page 67 and 68:
If the recommendations indicated in
Page 69 and 70:
- type of antibiotic, dosage and ro
Page 71 and 72:
diagnostic or surgical procedures a
Page 73 and 74:
RESPIRATORY TRACT PROCEDURES AND OP
Page 75 and 76:
- cephalexin § 2 g 30-60 minutes b
Page 77 and 78:
• Vascular graftsNo randomised co
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• infection of both superficial a
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- myocarditis, pericarditis- endoca
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Other CNS surgeryCaesarean sectionA
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2. Preparation of the surgical team
Page 87 and 88:
- For how many hours does the proto
Page 89 and 90:
11. Jobe BA, Grasley A, Deveney KE,
Page 91 and 92:
30. Scottish Intercollegiate Guidel
Page 93 and 94:
52. Wilcox MH, Cunniffe JG, Trundle
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71. Aznar R, Mateu M, Miro JM, Gate
Page 97 and 98:
93. Preclik G, Grune S, Leser HG, L
Page 99 and 100:
113. Sawaya GF, Grady D, Kerlikowsk
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133. Pitt HA, Postier RG, MacGowan
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153. Ballow CH, Schentag JJ. Trends
Page 105 and 106:
170. van Dijk-van Dam MS, Moll FL,
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188. Crowe MJ, Cooke EM. Review of
Page 109 and 110:
205. White A, Schneider T Improving
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